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Cellminer is described in (Shankavaram et al., 2009). If you wish to cite the tool, please cite the application URL, http://discover.nci.nih.gov/cellminer. If you would like to cite any data sets listed below, use the corresponding citation information below.
Public data sets citations
- DNA: BAC aCGH
- DNA: Mutation
- DNA: Chromosomal aberrations: spectral karyotyping
- DNA: Bisulfite sequencing of E-cadherin promoter
- DNA: Roche NimbleGen 385K aCGH
- RNA: Affymetrix HuEx 1.0
- RNA: Affymetrix HG-U133 Plus 2.0
- RNA: microRNA expression
- RNA: Affymetrix HG-U133
- RNA: Affymetrix HG-U95
- RNA: ABC Transporter (RT-PCR)
- RNA: ABC-Tox Chip
- RNA: Transporter Array
- RNA: Oncochip
- Protein: Lysate array
- Drug: A118
- Drug: A1429
- Drug: A4463
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel
Kimberly J. Bussey, Koei Chin, Samir Lababidi, Mark Reimers, William C. Reinhold, Wen-Lin Kuo, Fuad Gwadry, Ajay, Hosein Kouros-Mehr, Jane Fridlyand, Ajay Jain, Colin Collins, Satoshi Nishizuka, Giovanni Tonon, Anna Roschke, Kristen Gehlhaus, Ilan Kirsch, Dominic A. Scudiero, Joe W. Gray and John N. Weinstein
Mol Cancer Ther. 2006 Apr;5(4):853-67.
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
Ogechi N. Ikediobi, Helen Davies, Graham Bignell, Sarah Edkins, Claire Stevens, Sarah O’Meara, Thomas Santarius, Tim Avis, Syd Barthorpe, Lisa Brackenbury, Gemma Buck, Adam Butler, Jody Clements, Jennifer Cole, Ed Dicks, Simon Forbes, Kristian Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jonathan Hinton, Chris Hunter, Andy Jenkinson, David Jones, Vivienne Kosmidou, Richard Lugg, Andrew Menzies, Tatiana Mironenko, Adrian Parker, Janet Perry, Keiran Raine, David Richardson, Rebecca Shepherd, Alex Small, Raffaella Smith, Helen Solomon, Philip Stephens, Jon Teague, Calli Tofts, Jennifer Varian, Tony Webb, Sofie West, Widaa, Andy Yates, William Reinhold ,John N. Weinstein, Michael R. Stratton, P. Andrew Futreal, Richard Wooster
Mol Cancer Ther. 2006;5:2606-2612
Karyotypic Complexity of the NCI-60 Drug-Screening Panel
Anna V. Roschke, Giovanni Tonon, Kristen S. Gehlhaus, Nicolas McTyre, Kimberly J. Bussey, Samir Lababidi, Dominic A. Scudiero, John N. Weinstein and Ilan R. Kirsch
Cancer Research 63, 8634-8647, December 15, 2003
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells.
William C. Reinhold, Mark A. Reimers, Alika K. Maunakea, Sohyoung Kim, Samir Lababidi, Uwe Scherf, Uma T. Shankavaram, Micah S. Ziegler, Claudia Stewart, Hosein Kouros-Mehr, Hengmi Cui, Douglas Dolginow, Dominic A. Scudiero, Yves G. Pommier, David J. Munroe, Andrew P. Feinberg and John N. Weinstein
Mol Cancer Ther. 2007 Feb;6(2):391-403. Epub 2007 Feb 1.
Exon array analyses across the NCI-60 reveals potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.
William C. Reinhold, Jean-Louis Mergny, Hongfang Liu, Michael Ryan, Thomas D. Pfister, Robert Kinders, Ralph Parchment, James Doroshow, John N. Weinstein and Yves Pommier
Cancer Res. 2010 Mar 15; 70(6):2191-2203
Exon array analyses across the NCI-60 reveals potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.
William C. Reinhold, Jean-Louis Mergny, Hongfang Liu, Michael Ryan, Thomas D. Pfister, Robert Kinders, Ralph Parchment, James Doroshow, John N. Weinstein and Yves Pommier
Cancer Res. 2010 Mar 15; 70(6):2191-2203
Exon array analyses across the NCI-60 reveals potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.
William C. Reinhold, Jean-Louis Mergny, Hongfang Liu, Michael Ryan, Thomas D. Pfister, Robert Kinders, Ralph Parchment, James Doroshow, John N. Weinstein and Yves Pommier
Cancer Res; 2010 March 15, 70(6); 2191–2203
Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity.
Thomas D. Pfister, William C. Reinhold, Keli Agama, Shalu Gupta, Sonny A. Khin, Robert J. Kinders, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow, and Yves Pommier
Mol Cancer Ther 2009;8(7):1878–84
MicroRNA expression profiles for the NCI-60 cancer cell panel.
Blower PE, Verducci JS, Lin S, Zhou J, Chung JH, Dai Z, Liu CG, Reinhold W, Lorenzi PL, Kaldjian EP, Croce CM,Weinstein JN, Sadee W.
Mol Cancer Ther 2007;6(5):1483-91
Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
Uma T. Shankavaram, William C. Reinhold, Satoshi Nishizuka, Sylvia Major, Daisaku Morita, Krishna K. Chary, Mark A. Reimers, Uwe Scherf, Ari Kahn, Douglas Dolginow, Jeffrey Cossman, Eric P. Kaldjian, Dominic A. Scudiero, Emanuel Petricoin, Lance Liotta, Jae K. Lee, John N. Weinstein
Mol Cancer Ther 2007;6(3):820-32
Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
Uma T. Shankavaram, William C. Reinhold, Satoshi Nishizuka, Sylvia Major, Daisaku Morita, Krishna K. Chary, Mark A. Reimers, Uwe Scherf, Ari Kahn, Douglas Dolginow, Jeffrey Cossman, Eric P. Kaldjian, Dominic A. Scudiero, Emanuel Petricoin, Lance Liotta, Jae K. Lee, John N. Weinstein
Mol Cancer Ther 2007;6(3):820-32
Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells
Gergely Szakács, Jean-Philippe Annereau, Samir Lababidi, Uma Shankavaram, Angela Arciello, Kimberly J. Bussey, William Reinhold, Yanping Guo, Gary D. Kruh, Mark Reimers, John N. Weinstein, and Michael M. Gottesman
2004 Cell PressPII:Section: Cancer Cell, Vol 6, 129-137, August 2004
Analysis of ATP-Binding Cassette Transporter Expression in Drug-Selected Cell Lines by a Microarray Dedicated to Multidrug Resistance
Jean-Philippe Annereau, Gergely Szakács, Charles J. Tucker, Angela Arciello, Carol Cardarelli, Jennifer Collins, Sherry Grissom, Barry R. Zeeberg, William Reinhold, John N. Weinstein, Yves Pommier, Richard S. Paules, and Michael M. Gottesman
Mol Pharmacol 66:1397-1405, 2004
Membrane Transporters and Channels: Role of the Transportome in Cancer Chemosensitivity and Chemoresistance
Ying Huang, Pascale Anderle, Kimberly J. Bussey, Catalin Barbacioru, Uma Shankavaram, Zunyan Dai, William C. Reinhold, Audrey Papp, John N. Weinstein and Wolfgang Sadée
Cancer Res. 2004 Jun 15;64(12):4294-301
Apoptotic Susceptibility of Cancer Cells Selected for Camptothecin Resistance: Gene Expression Profiling, Functional Analysis, and Molecular Interaction Mapping
William C. Reinhold, Hosein Kouros-Mehr, Kurt W. Kohn, Alika K. Maunakea, Samir Lababidi, Anna Roschke, Kristen Stover, Jes Alexander, Panayotis Pantazis, Lance Miller, Edison Liu, Ilan R. Kirsch, Yoshimasa Urasaki, Yves Pommier, and John N. Weinstein
Cancer Res 2003 Mar 1;63(5):1000-11
Proteomic Profiling of the NCI-60 Cancer Cell Lines Using New High-density Reverse-phase Lysate Microarrays
Satoshi Nishizuka, Lu Charboneau, Lynn Young, Sylvia Major, William C. Reinhold, Mark Waltham, Hosein Kouros-Mehr, Kimberly J. Bussey, Jae K. Lee, Virginia Espina, Peter J. Munson, Emanuel Petricoin III, Lance A. Liotta , and John N. Weinstein
Proc Natl Acad Sci USA 2003 November 25th; 100(24): 14229-14234 [first 52 anitbodies]
Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
Uma T. Shankavaram, William C. Reinhold, Satoshi Nishizuka, Sylvia Major, Daisaku Morita, Krishna K. Chary, Mark A. Reimers, Uwe Scherf, Ari Kahn, Douglas Dolginow, Jeffrey Cossman, Eric P. Kaldjian, Dominic A. Scudiero, Emanuel Petricoin, Lance Liotta, Jae K. Lee, John N. Weinstein
Mol Cancer Ther 2007;6(3):820-32 [entire set of anitbodies]
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel
Kimberly J. Bussey, Koei Chin, Samir Lababidi, Mark Reimers, William C. Reinhold, Wen-Lin Kuo, Fuad Gwadry, Ajay, Hosein Kouros-Mehr, Jane Fridlyand, Ajay Jain, Colin Collins, Satoshi Nishizuka, Giovanni Tonon, Anna Roschke, Kristen Gehlhaus, Ilan Kirsch, Dominic A. Scudiero, Joe W. Gray and John N. Weinstein
Mol Cancer Ther. 2006 Apr;5(4):853-67.
Analysis of ATP-Binding Cassette Transporter Expression in Drug-Selected Cell Lines by a Microarray Dedicated to Multidrug Resistance
Jean-Philippe Annereau, Gergely Szakács, Charles J. Tucker, Angela Arciello, Carol Cardarelli, Jennifer Collins, Sherry Grissom, Barry R. Zeeberg, William Reinhold, John N. Weinstein, Yves Pommier, Richard S. Paules, and Michael M. Gottesman
Mol Pharmacol 66:1397-1405, 2004
Pharmacogenomic analysis: correlating molecular substructure classes with microarray gene expression data
P E Blower, C Yang, M A Fligner, J S Verducci, L Yu, S Richman and J N Weinstein
The Pharmacogenomics Journal (Nature) 2002; 2:259-271.
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