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'Omic' and Hypothesis-driven Research in the Molecular
Pharmacology of Cancer
Weinstein JN
Curr Opin Pharmacol 2002 Aug;2(4):361-5
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(Registraction required) |
Abstract: Given the layered, evolutionary complexity of biological systems, it will not be
possible to understand them comprehensively on the basis of hypothesis-driven research
alone. Likewise, it will not be possible to do so solely through 'omic' studies of
genes, proteins and other molecules in aggregate. The two modes of research are
complementary and synergistic. The twin complexities of cancer biology and drug
discovery demand such synergy as a basis for the next generation of oncopharmacomic
research.
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