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GoMiner: A Resource for Biological Interpretation
of Genomic and Proteomic Data
Zeeberg BR, Feng W, Wang G, Wang MD, Fojo AT, Sunshine M,
Narasimhan S, Kane DW, Reinhold WC, Lababidi S, Bussey KJ, Riss J, Barrett JC,
Weinstein JN
Genome Biol, 4(4):R28
Abstract:
We have developed GoMiner, a program package that organizes lists of 'interesting'
genes (for example, under- and overexpressed genes from a microarray experiment) for
biological interpretation in the context of the Gene Ontology. GoMiner provides quantitative
and statistical output files and two useful visualizations. The first is a tree-like structure
analogous to that in the AmiGO browser and the second is a compact, dynamically interactive
'directed acyclic graph'. Genes displayed in GoMiner are linked to major public bioinformatics
resources.
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