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This example output shows the ensembles that differ between cell lines with either Wildtype or Mutant copies of p53. It was generated using LeFEMiner and the following inputs:
  • Step 1: File defining samples as WildType or Mutant available here.
  • Step 2: The signature file contains classification data
  • Step 3: Gene expression of 50 NCI60 cell lines available here.
  • Step 4: Gene Symbol
  • Step 5: GO Biological Process, GO Molecular Function, GO Cellular Compartment and MSigDB Curated Gene Sets.
  • Step 6: Gene ensembles from size 2 to 50.

Number of Genes:0
Number of Categories Within Size Range:0
Number of Samples:0
Gene Expression File:
Signature File:
Customer Category File:
Identifier Type:
Category Size Range:
Signature File Interpretation:
Execution Time:

You can view rest of the results at: Results Archive

Help in understanding the table below can be found at the Understanding Your Results page.

Category Rank Category Name Category Size Median Category p-Value(see note) False Discovery Rate Original Category Order Top 5 most Important Genes with Importance Scores Importance Score Distribution (click to enlarge)

You can view rest of the results at: Results Archive


LeFE™ is a development of the Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology (LMP), Center for Cancer Research (CCR), National Cancer Institute (NCI). Please email us with any problems, questions or feedback on the tool.

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