"Drug activity data of 118 'Mechanism of Action' drugs" Mechanism of action Drug NSC No. ME:LOXIMVI ME:MALME-3M ME:SK-MEL-2 ME:SK-MEL-5 ME:SK-MEL-28 LC:NCI-H23 ME:M14 ME:UACC-62 LC:NCI-H522 LC:A549/ATCC LC:EKVX LC:NCI-H322M LC:NCI-H460 LC:HOP-62 LC:HOP-92 CNS:SNB-19 CNS:SNB-75 CNS:U251 CNS:SF-268 CNS:SF-295 CNS:SF-539 CO:HT29 CO:HCC-2998 CO:HCT-116 CO:SW-620 CO:HCT-15 CO:KM12 OV:OVCAR-3 OV:OVCAR-4 OV:OVCAR-8 OV:IGROV1 OV:SK-OV-3 LE:CCRF-CEM LE:K-562 LE:MOLT-4 LE:SR RE:UO-31 RE:SN12C RE:A498 RE:CAKI-1 RE:RXF-393 RE:786-0 RE:ACHN RE:TK-10 ME:UACC-257 LC:NCI-H226 CO:COLO205 OV:OVCAR-5 LE:HL-60 LE:RPMI-8226 BR:MCF7 BR:MCF7/ADF-RES PR:PC-3 PR:DU-145 BR:MDA-MB-231/ATCC BR:HS578T BR:MDA-MB-435 BR:MDA-N BR:BT-549 BR:T-47D A2 Mitomycin 26980 6.54285 6.07549 5.77834 6.438135 5.72194 6.90796 6.40159 6.92035 6.177225 6.70863 5.26081 5.990695 7.75413 6.970185 5.40171 6.48873 6.372685 6.44383 6.27943 6.81383 6.65397 6.101185 6.15206 6.153235 6.309885 5.86996 5.5855 5.44192 5.43416 5.91205 5.4921 6.01668 6.64888 5.68723 6.62435 6.90543 5.61546 6.62222 6.14637 6.55416 5.58242 6.35124 6.82955 5.294375 5.83195 6.13349 5.94757 5.8314 6.7195 5.525155 6.71785 5.22548 5.54335 6.72576 5.07043 5.45696 5.664945 5.6831 5.613885 5.65978 A2 Porfiromycin 56410 5.817545 5.33731 4.85471 5.70779 4.861285 6.05217 6.182065 6.2239 5.149235 6.34561 4.66881 5.1687 7 6.441165 4.864365 5.61831 5.80833 5.82612 5.300955 6.28128 5.46823 5.465775 5.46312 5.45365 5.53024 5.259955 4.853285 5.0294 4.94665 5.15494 4.93901 4.9955 5.70109 4.77805 6.16626 6.63448 4.76919 6.060835 5.24486 5.73578 4.932985 5.75122 6.32652 4.87799 4.97921 5.08703 5.31908 4.99265 6.13311 5.08124 6.15684 4.51405 4.95101 6.591095 4.392485 4.75949 4.88399 4.905395 4.914535 5.03553 A6 Carmustine (BCNU) 409962 4.40145 4.0578 4.074825 4.098515 4.07481 4.0603 4.11591 4.6864 4.21775 3.99513 3.970805 3.77866 4.24084 4.0019 4.15819 4.18994 4.22387 4.26858 4.39397 4.3206 4.30183 4.071725 4.01208 4.1372 4.2472 4.166505 4.06488 4.05267 4.06825 4.075695 4.120355 3.97008 4.756625 4.33787 4.51698 4.82159 3.991605 4.117915 3.96246 4.13681 4.10409 4.405295 4.086635 4.04157 4.09841 4.00409 4.12606 3.99212 4.842675 4.24068 4.07802 4.02138 3.9817 3.69171 4.03743 3.9835 4.07794 4.09326 4.093075 3.93558 A6 Chlorozotocin 178248 4.02047 3.24679 3.097935 3.12388 2.90309 2.91706 3.09037 4.290725 2.90309 2.92216 2.90309 2.90309 3.516875 3.41585 3.49363 3.61027 3.45249 3.779565 3.978495 4.00879 4.04707 2.90309 2.90309 3.11997 2.95962 2.90309 2.90309 2.90309 2.90309 2.90309 2.90309 2.90309 3.42919 3.315135 3.96728 3.28717 2.90309 3.018525 2.90309 3.13041 2.90309 4.231265 3.46455 2.90309 2.90309 2.90309 2.90309 2.90309 3.57727 2.90309 2.90309 2.90309 2.90309 3.264245 2.90309 2.90309 3.09018 3.475245 3.39559 3.219855 A6 Clomesone 338947 4.32955 3.33044 3.2961 3.65128 3.30692 3.860375 3.69275 4.488885 3.67143 3.59814 3.47086 3.2774 4.01329 3.80728 3.836 3.93708 4.04251 4.13982 4.18371 4.34411 4.239315 3.33335 3.55072 3.75908 3.82384 3.697 3.57656 3.653705 3.383445 3.472395 3.36817 3.32416 3.896115 3.749565 4.020405 5.23725 3.262945 3.660485 3.27077 3.67863 3.82243 4.259275 3.823535 3.249655 3.80765 3.4757 3.29994 3.15418 4.02872 3.83902 3.70543 3.59003 3.33444 3.68151 3.49964 3.691855 3.003955 3.98783 4.00233 3.674795 A6 Lomustine (CCNU) 79037 4.99879 4.1155 4.09856 4.19847 4.14139 4.13882 4.22347 4.85028 4.5228 4.23157 4.03312 4.090615 4.49644 4.088255 4.284105 4.2431 4.398775 4.44135 4.615395 4.47376 4.6618 4.21249 4.11322 4.36655 4.46376 4.52626 4.125935 4.12501 4.13576 4.21498 4.19097 4.054585 4.85815 4.64631 4.71651 5.01316 4.08089 4.28079 4.099385 4.32471 4.189735 4.56131 4.165975 4.11268 4.16329 4.17487 4.18992 4.04294 4.809555 4.750115 4.29629 4.22503 4.16718 4.12049 4.304055 3.92932 5.20372 4.249515 5.27857 4.44571 A6 Mitozolamide 353451 4.731115 3.74116 3.56866 3.77366 3.615655 3.793535 3.693065 4.60519 3.795525 3.76463 3.56178 3.73257 4.32452 4.26041 3.85334 3.98081 4.340585 4.33093 4.46766 4.509935 4.4291 3.81196 3.799285 3.89396 3.790935 3.720205 3.80173 3.72596 3.825315 3.81631 3.68599 3.8009 4.33174 4.12845 4.47996 4.19436 3.651375 3.946815 3.697855 3.9211 3.78677 4.491845 4.27474 3.65889 3.77257 3.725775 3.771795 3.556145 4.43563 3.775235 3.87884 3.782515 3.75687 3.99778 3.65897 3.621605 3.76498 3.854145 3.99801 3.602995 A6 PCNU 95466 4.33081 3.64687 3.578815 3.67647 3.40596 3.57831 3.506665 4.779115 3.634405 3.81766 2.90309 3.25923 4.09355 3.80423 3.62698 3.95497 4.126415 4.27169 4.37035 4.65021 4.293095 3.133975 3.14472 3.69978 3.78643 3.52329 3.56408 3.03849 2.90309 4.157885 3.50421 3.193175 4.04538 3.659225 4.23779 4.9526 3.12418 3.64734 3.65588 3.56692 3.616435 4.223365 3.33637 3.367195 3.460845 3.356235 3.605155 3.039855 4.12834 3.67489 3.46447 3.57617 2.99223 3.45534 3.51376 3.48949 3.712225 3.62613 3.63048 3.59435 A6 Semustine (MeCCNU) 95441 4.709235 4.34633 4.331 4.39817 4.34495 4.274105 4.39454 4.969365 4.32937 4.21672 4.092725 3.94134 4.41195 4.241385 4.40833 4.43885 4.41488 4.51967 4.575 4.56525 4.55002 4.269145 4.3448 4.38694 4.493745 4.350315 4.255275 4.35866 4.33397 4.31126 4.40211 4.03334 4.59333 4.352 4.46685 4.976345 4.28483 4.360185 4.25634 4.340715 4.369485 4.506915 4.31397 4.225315 4.32669 4.199555 4.344315 4.23392 4.38598 4.43635 4.34616 4.30776 4.33332 4.010215 4.303455 4.22446 4.430675 4.346035 4.3441 4.3144 A7 Asaley 167780 5.588755 5.598635 5.60337 5.46394 5.22577 5.35069 5.54795 5.751415 5.77378 4.83439 4.72548 4.661255 5.465335 5.26533 5.7995 4.86167 4.8975 5.11878 5.37966 5.18218 5.55292 4.76997 4.83524 4.7864 5.10449 4.99057 4.68642 5.38939 4.7542 5.086545 4.86254 4.7786 6.1655 5.29867 6.3916 5.97853 5.164445 5.4972 4.72911 6.006 5.67488 5.64394 5.60434 4.79285 5.44832 4.78924 5.45753 4.78529 6.43045 5.52674 5.36727 4.721655 4.7942 5.22155 5.18739 5.409305 5.47429 5.56995 5.26979 5.6445 A7 Busulfan 750 5.22467 3 3 3.300685 3 3.121875 3.094875 3.36012 3.49494 3.27941 3 3 3.640135 3.26719 3.160135 3 3.38785 3.29419 3.368645 3.37927 3.32853 3 3 3.13238 3 3 3 3 3 3 3 3.08828 3.56412 3.091125 3.84908 4.17631 3 3.13702 3 3.54028 3.16424 3.319465 3.45214 3 3.34224 3 3 3 3.671605 3.036895 3.33767 3 3 3.12019 3 3 3 3 3 3.21072 A7 Carboplatin 241240 4.15379 4.13384 3.60206 3.9297 3.65134 4.194805 3.93966 4.365015 4.21979 3.95315 3.60206 3.60206 4.469725 3.80921 3.8471 3.75397 3.98431 4.171085 4.24976 4.171195 4.07922 3.60206 3.60206 3.60206 3.60206 3.60206 3.60206 4.214025 4.11085 3.60206 4.24698 3.60206 4.10206 3.60206 4.02451 4.19357 3.687845 3.7641 3.60206 4.03466 4.05232 4.01779 4.06251 3.60206 3.905925 3.95644 3.60206 3.60206 4.570165 3.60206 3.80814 3.638665 3.60206 3.82943 3.60206 3.903115 3.66874 3.640325 4.0081 3.60206 A7 Chlorambucil 3088 4.39983 4.068685 3.82189 4.009325 3.94697 4.553385 4.2007 4.690955 4.60168 4.23883 3.75583 3.71598 4.79481 4.461415 4.02233 4.01741 4.151545 4.38379 4.48307 4.401905 4.677475 3.88206 3.94446 3.96494 4.03232 4.02214 3.868055 3.866795 3.85847 4.07602 3.89862 3.92312 5.22221 3.94444 5.31299 5.32211 4.11693 4.46474 3.8758 4.75566 4.54058 4.532025 4.80915 3.75167 3.964555 4.00002 3.92682 3.99425 5.17458 4.16386 4.44105 4.151105 3.99846 4.21055 3.793715 3.78546 3.939235 3.973275 3.985005 4.24797 A7 Cisplatin 119875 5.75486 5.73754 5.07841 5.4124 5.138155 5.98138 5.550535 5.784585 5.52435 5.32778 4.943765 5.040055 6.11622 5.593315 5.28546 5.32508 5.50978 5.62449 6.05623 5.92509 5.712955 4.963395 5.1063 5.1906 5.20551 5.03838 4.90482 5.45923 5.76648 5.1967 5.65768 5.07786 5.81575 5.08895 5.77467 6.15103 5.24592 5.18793 5.00676 5.6295 5.26167 5.7323 5.704275 4.91054 5.195575 5.138265 4.84675 5.123795 6.29571 5.19095 5.47088 5.22787 5.179875 5.65766 4.740675 5.13424 5.15693 5.18072 5.20942 4.810845 A7 Cyclodisone 348948 4.83864 4.21104 4.30074 4.417795 4.11037 4.38566 4.29948 4.9562 4.348835 4.422235 4.189225 4.118555 4.89378 4.46741 4.35589 4.46843 4.56995 4.66285 4.7812 4.92064 4.914295 4.238085 4.40087 4.43288 4.31555 4.30111 4.29366 4.339895 4.319965 4.2879 4.308175 4.16088 4.72706 4.20452 4.977775 4.31764 4.21989 4.30083 4.27191 4.399555 4.42738 4.876815 4.82105 4.06981 4.29644 4.32117 4.32921 4.10179 4.972975 4.36348 4.316135 4.27955 3.96934 4.292125 3.99445 4.21879 4.405325 4.459825 4.43786 4.27817 A7 Diaminocyclohexyl-Pt-II 271674 5.54434 5.98983 4.718245 5.91555 5.40148 5.59878 5.29955 5.626535 5.61901 5.98385 4.721345 4.923035 6.27314 4.724935 4.87363 4.93812 4.835575 5.24711 5.40664 5.52122 5.433415 6.12514 5.09592 6.19868 6.37858 5.7657 5.16858 5.30818 5.35234 5.65059 5.39189 4.590465 6.017155 5.817345 6.35639 5.94335 5.151225 5.69465 4.90773 6.08628 5.25383 6.23367 6.21113 4.74796 5.049175 5.75522 5.7353 5.35249 6.077395 6.37134 5.78816 5.58403 5.52795 5.16152 4.772325 5.05948 6.01503 5.73918 4.93436 5.59635 A7 Dianhydrogalactitol 132313 4.65496 4.08721 3.82391 4.21294 3.82391 4.63271 4.81604 4.973865 4.13314 4.64003 3.82391 3.82391 5.420225 4.77561 3.82391 4.04345 4.34864 4.47651 4.42548 4.873665 4.37016 3.82391 3.99671 4.25041 3.82391 4.00179 3.82391 3.88954 3.82391 4.06216 3.82391 4.13509 5.05458 3.890355 5.23086 5.715355 3.85332 4.611615 3.82391 4.67708 3.992195 5.101245 5.3469 3.998295 3.902 3.96636 3.82391 3.88108 5.2747 3.902695 4.90423 4.19363 4.38402 5.0299 3.84713 4.02884 4.336585 4.551115 4.52982 4.646025 A7 Diaziridinylbenzoquinone 182986 5.60611 5.249655 5.207575 5.42889 4.86943 5.73808 5.597765 6.29253 5.45907 5.72817 5.22325 4.74165 6.79421 6.07567 5.29237 5.363165 5.354975 5.57458 5.535445 5.94859 5.82013 5.15437 5.17369 5.45364 5.340685 5.07794 5.03446 5.289635 5.317895 5.41142 5.248365 5.3016 5.90345 5.29893 5.83878 6.27073 5.263085 5.84989 5.41167 5.85522 5.35327 5.82599 6.150555 4.46715 5.33642 5.407915 5.13024 5.146045 6.39323 5.39785 5.65426 5.35112 NA NA NA NA NA NA NA NA A7 Fluorodopan 73754 3.52105 3.47298 3.32135 3.384085 3.37147 3.464185 3.43197 3.49273 3.86595 3.25237 3.317755 3.26001 3.710065 3.28443 3.88863 3.21913 3.36151 3.40326 3.48834 3.364365 3.462265 3.368365 3.44127 3.38367 3.48988 3.37424 3.31629 3.32045 3.46658 3.39682 3.347 3.26235 4.09172 3.349385 4.23216 4.099365 3.2466 3.38608 3.30275 3.46699 3.566645 3.35369 3.66952 3.31987 3.29326 3.20089 3.38805 3.28227 4.17373 3.52867 3.5697 3.33898 3.43245 3.26263 3.297435 3.14825 3.3895 3.3967 3.50527 3.55249 A7 Hepsulfam 329680 3.84696 3.34351 3.30313 3.50793 3.26381 3.5575 3.749495 4.308455 3.5395 3.86586 3.34251 3.22639 4.79919 3.960145 3.51587 3.56662 3.93722 3.71468 3.91334 4.0673 3.91659 3.33051 3.43159 3.52777 3.48069 3.426475 3.40305 3.433095 3.370305 3.54198 3.39425 3.35582 4.26207 3.46674 4.614605 4.500525 3.5407 3.87562 3.44441 4.21865 3.484655 3.83508 4.230785 3.190785 3.41067 3.48155 3.406405 3.24717 4.618785 3.51832 3.92808 3.54054 3.569465 3.88717 3.337185 3.23556 3.38702 3.37545 3.819725 3.672945 A7 Iproplatin 256927 4.72537 4.727765 4.37873 4.681215 4.427675 4.56066 4.37508 4.54171 4.75155 4.43718 4.18446 4.502465 5.02113 4.29757 4.29334 4.23809 3.97704 4.58348 4.40027 4.30491 4.33135 4.82764 4.010305 4.72751 4.64535 4.43125 4.019795 4.64876 4.540515 4.4719 4.52317 4.5769 5.27161 4.4963 4.93255 4.91457 3.798105 4.49571 3.77966 4.52934 4.557555 4.451735 4.871905 3.74675 4.031065 4.20013 4.57264 4.1877 4.79756 4.481995 4.67851 4.23423 3.98151 4.41424 4.198775 3.97337 4.58436 4.68119 4.41299 4.299285 A7 Mechlorethamine 762 5.62412 5.89173 5.0067 5.323755 5.04459 5.91527 5.29577 5.64094 6.17557 5.674395 5.15095 5.01438 6.876455 5.23678 6.1151 4.79265 4.874865 5.56341 5.504685 5.47829 5.81819 5.27636 5.23671 5.37607 5.63231 5.56973 5.176095 5.170425 5.05414 4.939995 5.17264 5.08629 6.67897 5.11507 6.56103 6.806045 5.10014 6.11371 5.154085 6.30023 5.672105 5.78095 6.65571 5.09158 5.205655 5.03051 5.27258 5.158565 6.70756 5.79073 5.71265 5.11051 5.365375 6.11354 4.84769 4.296595 5.12913 5.146365 5.22906 6.50511 A7 Melphalan 8806 4.74759 4.51915 4.27896 4.43541 4.27918 4.623305 4.67815 4.94934 4.48936 4.56699 4.26497 4.14588 5.082775 4.79237 4.42134 4.30761 4.43498 4.57577 4.72923 4.752425 4.81525 4.17641 4.33475 4.415055 4.4416 4.42204 4.17602 4.32065 4.37989 4.45474 4.29433 4.48575 5.65107 4.31619 5.66124 5.77899 4.35231 4.85864 3.916255 4.84301 4.49079 4.83196 4.948145 4.22652 4.37632 4.3454 4.37204 4.3216 5.61294 4.370455 4.93023 4.31834 4.472245 4.370835 4.219915 4.259795 4.389635 4.35817 4.47116 4.87131 A7 Piperazine mustard 344007 4.10381 3.90024 3.468005 3.667835 3.42757 4.13316 3.889735 4.914915 4.00001 3.90987 3.648535 3.04374 5.18451 4.206285 3.84887 3.73183 3.903105 3.992135 4.21318 4.34301 4.43267 3.56969 3.4941 3.68278 3.706665 3.68477 3.25571 3.73146 3.73952 3.878315 3.5539 3.69993 5.061 3.71736 5.11821 4.97775 3.7906 4.53066 3.687185 4.771125 3.83435 4.354655 5.02106 3.391735 3.6753 3.758395 3.82311 3.65418 5.21132 3.830605 4.27091 3.85009 3.61905 4.21767 3.373235 3.54241 3.51497 3.742605 3.80895 4.17218 A7 Piperazinedione 135758 6.66624 5.9233 5.50518 5.90325 5.5103 6.6553 6.81625 7 5.95141 6.58163 5.43171 5.20964 7 6.69686 5.834545 5.85122 6.061035 6.45612 6.45977 6.81094 6.343755 5.60443 5.763005 6.026 5.766035 5.74202 5.39474 5.585965 5.57969 5.97107 5.35164 5.82511 7 5.65076 7 7 5.73717 6.74477 5.64113 6.51439 5.875975 7 7 5.354725 5.52327 5.75869 5.69416 5.703385 7 5.58245 7 5.880275 5.8834 7 5.65339 5.296015 5.972885 6.1368 5.78908 6.65317 A7 Pipobroman 25154 4.25505 4.0094 3.9777 4.12989 4.00803 4.20731 4.19308 4.728805 4.146745 4.25852 3.96037 3.96456 4.96627 4.18633 3.95623 4.053455 4.11617 4.23056 4.316315 4.21333 4.17905 4.04019 4.069195 4.147465 4.05927 4.08224 4.06738 3.98742 4.08305 4.046875 4.00664 3.97933 4.695645 3.84962 4.82558 5.175325 3.92125 4.31272 4.07561 4.18972 4.129915 4.167845 4.524985 3.62829 4.03724 4.10758 4.04283 4.013375 4.81614 3.93414 4.25778 4.11144 3.99258 4.16661 3.92761 3.756675 4.02962 4.064895 4.11696 3.809275 A7 Spiromustine 172112 4.0254 3.60206 3.60206 3.60206 3.60206 4.072045 NA 4.18796 4.24087 3.76483 3.60206 3.60206 4.118445 3.79921 4.19041 3.65687 3.60356 3.656265 4.06377 3.96783 4.09594 3.60206 3.60206 3.64719 3.680505 3.60206 3.60206 3.60206 3.60206 3.60206 3.60206 3.60206 4.3745 3.60206 4.482955 NA 3.60206 3.96455 3.60206 4.385305 4.141025 NA NA NA 3.60206 3.60206 3.60206 3.60206 4.50751 3.86548 3.99809 3.60206 NA NA NA NA NA NA NA NA A7 Teroxirone 296934 4.85672 4.48022 4.403095 4.57458 4.471465 5.094125 4.93876 5.86844 5.23765 5.20218 4.38643 4.52135 5.93845 4.804005 4.50809 4.6772 4.90786 5.294365 4.84648 5.33578 5.288685 4.76828 4.72267 4.91166 4.54945 4.86223 4.505825 4.858435 4.46621 4.59857 4.53667 4.6774 5.66241 4.59857 6.02224 5.90245 4.52013 5.37836 4.8516 5.292625 4.72794 5.12498 5.98724 4.39056 4.734265 4.5588 4.78155 4.366385 6.105785 4.846145 5.29699 4.76964 4.61967 5.05328 4.34599 4.425915 4.747765 4.5216 4.70398 4.720715 A7 Tetraplatin 363812 6.033375 6.70863 5.23656 6.46833 5.888925 5.909335 5.73874 6.250655 6.39314 6.15128 4.8758 5.183225 6.40877 5.31156 5.215635 5.397505 5.242695 5.79523 5.85206 6.00152 5.85206 6.517375 6.055255 6.661755 6.743685 6.159425 5.739625 5.6813 5.54364 5.87978 6.102025 5.003585 6.56652 6.27094 6.903565 6.24542 5.63711 6.04875 5.37725 6.15802 5.61882 6.735235 6.00389 5.193495 5.54272 5.98384 6.26871 5.700835 6.49272 7.0142 6.21678 5.82379 5.9858 5.48543 4.471495 5.451685 5.985155 6.087815 5.59054 5.94928 A7 Thiotepa 6396 4.399925 3.80185 3.6796 3.91724 3.72079 4.4378 4.13672 4.873885 3.96464 4.2874 3.55091 3.62366 5.28829 4.48089 3.81433 3.880645 3.98424 4.22418 4.42117 4.49834 4.45406 3.81692 3.87306 3.91479 3.823695 3.83542 3.7829 3.75652 3.72338 3.938275 3.77809 3.9016 5.03805 3.79282 5.16864 5.159605 3.96211 4.451465 3.86472 4.51067 3.922605 4.41489 4.82209 3.4815 3.84564 3.885275 3.805635 3.84482 5.18193 3.705645 4.466685 3.9995 3.75954 4.38398 3.580515 3.42727 3.814745 3.84253 3.80378 3.741315 A7 Triethylenemelamine 9706 5.49618 4.904545 4.74009 5.17079 4.82588 5.54915 5.31844 5.72766 5.296885 5.29211 4.62273 4.71684 6.38258 5.66573 4.91107 5.09747 5.253375 5.40834 5.54785 5.555915 5.56919 4.84195 4.923755 4.99784 4.923395 4.882975 4.808085 4.75631 4.77103 5.058415 4.81198 5.03707 6.12676 4.971615 6.32915 6.339775 5.10147 5.57649 4.92612 5.63356 5.02676 5.51222 6.07076 4.54978 4.88865 4.97628 4.83902 4.93178 6.219125 4.83744 5.62404 5.22304 4.84497 5.43273 4.6642 4.60427 4.86355 4.857625 4.7837 5.09055 A7 Uracil mustard 34462 4.86274 4.37033 4.03085 4.26535 4.13087 4.8651 4.69077 5.14307 4.90127 4.61669 4.02987 3.95266 5.4713 4.841935 4.59917 4.324905 4.56507 4.82041 4.869305 4.80155 4.923445 4.14579 4.13753 4.28475 4.26032 4.26727 4.0552 4.0572 4.08996 4.2966 4.0924 4.24961 5.63377 4.334015 5.77502 5.843475 4.34945 5.01888 4.11117 5.44485 4.717415 4.98714 5.50669 3.97048 4.239595 4.24357 4.16649 4.33344 5.772725 4.35928 4.75422 4.566495 4.26397 4.662135 4.04838 4.048075 4.19475 4.22775 4.2162 5.077 A7 Yoshi-864 102627 3.0623 2.76817 2.64116 2.8205 2.61596 2.89733 2.837655 3.407895 2.71503 3.12944 2.648435 2.67373 3.72987 3.16803 2.81749 2.78954 2.77203 3.004655 3.0804 3.32868 2.815105 2.738635 2.769355 2.8647 2.820725 2.72767 2.72305 2.69029 2.63751 2.71121 2.60495 2.65028 3.480935 2.71813 3.656265 3.74798 2.607795 3.222425 2.76758 3.213675 2.7154 3.044135 3.342475 2.636975 2.71683 2.65857 2.76391 2.65776 3.61244 2.82238 3.183455 2.75255 2.91427 3.157585 2.537825 2.58694 2.64408 2.604045 2.82446 2.94026 T1 Camptothecin 94600 7.63805 6.768895 6.46891 7.52587 6.685125 7.66723 7.68451 8 7.74759 7.899025 6.939955 6.769625 8 8 7.21967 7.835875 7.46352 8 8 8 8 7.256995 6.68834 7.71354 7.492425 6.85542 6.88388 6.74523 6.637095 7.59498 6.68315 7.675975 8 7.22152 8 8 7.57459 7.94061 7.6173 8 7.62289 7.67047 7.93415 5.87847 7.196695 7.885415 6.57351 6.98894 8 7.56446 8 8 7.19132 8 6.02817 6.08842 7.18153 6.83799 6.93993 7.64661 T1 "Camptothecin,7-Cl" 249910 8 6.51306 6.09356 8 6.47178 8 8 8 8 8 6.22565 6.689205 8 8 7.222065 8 7.91538 8 8 8 8 7.225785 6.28319 7.79635 7.560355 6.71926 6.6752 6.52188 6.251545 7.97166 6.49863 7.789595 8 7.56757 8 8 8 8 7.76747 8 8 8 8 4.96522 6.63235 8 6.30273 7.26071 8 8 8 8 7.66964 8 5.079945 5.34493 7.007225 7.161265 7.866975 8 T1 "Camptothecin,9-MeO" 176323 8 6.915375 6.667135 7.86767 6.2461 8 7.39988 8 7.68033 7.871285 6.50537 6.70702 8 8 7.33473 8 7.905465 8 8 8 8 7.021645 5.415075 7.74369 7.413045 6.71072 6.73609 6.565945 6.61384 7.758455 6.66214 7.861725 8 7.14986 7.70852 8 7.987625 8 6.95571 8 7.59655 7.35105 8 5.826615 6.73912 7.72184 6.441905 7.081145 8 7.94542 6 5.777145 5.81497 6 5.22074 4.89413 6.632305 6 5.30613 4 T1 "Camptothecin,9-NH2 (RS)" 629971 8 6.76238 6.46151 7.6 6.73353 8 8 8 8 7.28872 6.06002 6.88068 8 8 7.48317 8 7.968995 8 8 8 8 6.931665 6.50871 7.88036 7.75957 6.61633 6.52632 6.49236 6.45488 7.56458 6.42667 7.56538 8 7.54808 8 8 8 8 6.90988 8 7.53267 8 8 5.43343 6.93296 8 6.09517 6.97582 8 7.33109 8 7.92865 6.937635 7.958745 5.677445 5.43773 7.21726 6.740935 7.17536 7.85988 T1 "Camptothecin,9-NH2 (S)" 603071 8 6.96265 6.66624 7.92172 6.7811 8 8 8 7.86124 7.677135 6.02211 6.91538 8 8 7.43433 8 8 8 8 8 8 7.14185 6.85223 7.81553 7.647325 6.77182 6.57891 6.803665 6.56221 7.89893 6.65679 7.91933 8 7.367965 8 8 7.966625 8 7.21215 8 7.341065 8 8 5.94495 7.175675 8 6.5703 6.74409 8 6.80103 8 8 7.12226 8 6.5841 5.3951 6.96619 6.96649 6.86219 8 T1 "Camptothecin,10-OH" 107124 8.08003 7.244505 6.353855 7.61545 6.784195 7.927995 NA 8.12494 8.12494 7.21423 7.052995 6.97418 7.78629 8.12494 7.31171 8.12494 7.85439 8.12494 8.12494 7.65481 8.12494 6.80213 7.13059 7.806605 7.58857 6.6025 6.93271 7.25071 6.83604 7.964795 6.3009 7.64213 8.12494 7.22837 8.12494 NA 7.784315 8.049125 6.94298 8.12494 7.333295 NA NA NA 7.38615 8.0964 6.49621 7.547745 7.64571 6.593195 8.12494 7.71949 NA NA NA NA NA NA NA NA T1 "Camptothecin,11-formyl (RS)" 606172 6.30135 5.44353 4.84646 5.69798 4.63039 5.71895 5.94571 6.39569 5.57015 5.54933 4.77585 5.09745 6.30268 6.63278 5.04356 5.51533 5.97095 6.26776 6.4085 5.490685 6.30275 5.3058 5.33521 5.8822 5.98799 5.216305 4.0626 5.29139 5.46068 5.79389 5.12955 5.68548 7.30815 5.68115 6.91243 7.886575 5.65811 6.35906 5.38306 5.76249 5.657815 6.24493 6.18649 4.37998 5.23595 5.80054 4.95075 5.33625 5.899 5.5655 6.72754 5.87629 5.29931 6.30961 4.71276 4.56866 5.2293 5.4084 5.34111 6.38462 T1 "Camptothecin,11-HOMe (RS)" 606173 5.737875 5.343765 4.743615 5.51061 4.1049 5.682755 5.44451 6.1211 5.786295 5.21867 4.775135 5.14354 5.96426 6.24736 4.787645 5.715375 5.66108 6.15162 6.001615 5.497325 5.84889 5.029145 5.08347 5.313705 5.12401 4.80669 5.02928 5.34224 4.6236 5.582185 4.912375 5.645225 6.7312 5.36705 6.492185 7.18993 5.418665 5.813895 5.106915 5.52676 5.139055 5.701995 5.54446 4.02137 4.9138 5.799005 4.846825 5.047055 5.589875 5.149575 NA NA NA NA NA NA NA NA NA NA T1 "Camptothecin,20-ester (S)" 606497 7.05706 5.81491 5.57527 6.56913 5.457 7.24984 6.72736 7.483615 6.67526 6.764975 5.41617 5.93555 7.504015 7.34171 5.878125 6.92618 6.52452 7.2369 7.12126 7.22783 7.297715 6.08082 5.89576 6.511185 6.4308 5.73741 5.840335 5.661235 5.570005 6.580055 5.726755 6.649225 7.922565 6.224035 7.63741 8 6.66587 7.193905 6.2293 7.30118 6.577505 7.309055 7.370705 5.074085 6.18987 6.76581 5.80618 6.31238 7.20739 6.624905 7.15923 6.94336 6.12987 7.332695 5.172975 4.587695 5.864535 5.86829 5.97931 6.692835 T1 "Camptothecin,20-ester (S)" 606985 8.05049 6.708305 6.30761 7.72766 6.070135 7.719175 7.747585 8.104115 7.440995 7.32606 6.7851 6.662425 8.483025 7.02419 7.01292 7.894225 7.73825 7.92964 8.161775 8.60464 7.42247 6.95605 6.7581 7.284715 7.348345 6.717435 7.65799 6.511135 6.59155 7.39794 6.874335 7.65033 8.93458 6.770385 8.858115 9.90406 7.78695 8.145685 7.890725 8.13109 6.82938 8.249825 8.32268 6.142185 7.06585 7.81985 6.55901 7.137945 8.117275 7.5084 7.60085 7.76082 6.76499 8.27122 6.18569 6 6.88497 6.91207 6.3379 7.37028 T1 "Camptothecin,20-ester (S)" 610456 7.443025 6.40915 5.758955 6.90559 5.99675 7.27196 7.28991 7.79431 6.925865 7.105635 5.91234 6.33856 8 7.94865 5.93695 7.28434 6.94438 7.588245 7.41804 7.58703 7.520845 6.538305 6.33855 6.982635 6.85392 6.31309 6.20122 6.04551 5.84135 6.832545 6.317885 6.810225 8 6.454665 8 8 7.153405 7.46682 6.69699 7.55618 6.57078 7.5315 7.639905 5.455765 6.6314 7.01069 6.00808 6.478025 7.50393 6.69477 7.54174 7.417215 6.621555 7.56746 5.412935 4.835825 6.36242 5.964315 6.314875 7.186845 T1 "Camptothecin,20-ester (S)" 618939 7.702925 6.3 6.03693 7.48416 6.49311 7.46823 7.26162 8.14668 6.384 7.37378 6.04881 6.59415 8.06569 7.631105 7.00106 7.7491 7.12534 7.91869 7.78302 7.66424 7.70016 6.91753 6.839025 7.5302 7.04966 6.66234 6.6958 6.45206 6.30588 7.33356 6.615805 7.11708 8.69824 7.11467 8.4563 8.67223 7.5555 7.48007 6.68921 7.675515 6.85706 7.58741 8.05857 5.65909 6.86255 7.34673 6.404235 6.60651 7.98033 8.33354 8.06861 7.37555 7.011895 7.884665 5.484895 5.372695 6.711505 6.76312 7.270925 7.692325 T2 Amonafide 308847 5.53792 5.495635 5.35161 5.46522 5.16955 5.411025 5.42921 5.46724 5.404215 5.77406 5.192275 5.31782 6.01365 5.56442 5.44946 5.35181 5.25778 5.38993 5.212025 5.466995 5.34536 5.44817 5.44166 5.73826 5.76056 5.49188 5.315085 5.29804 5.31693 5.56979 5.39297 5.30132 5.53108 5.5346 6.09872 5.84838 5.35682 5.45821 5.44609 5.82335 5.39077 5.62578 6.110815 5.383905 5.328075 5.56503 5.6807 5.24817 5.576225 5.34805 5.81394 5.47144 5.66769 5.512845 5.28177 5.307985 5.47237 5.6183 5.369 5.25247 T2 Amsacrine 249992 6.703275 6.17951 5.415295 6.44821 5.524925 6.856085 6.6207 6.62916 6.21282 7.60206 5.55666 5.40503 7.60206 7.16393 6.2031 6.48301 6.33704 6.79451 6.308335 6.96374 6.69288 5.69458 5.86917 6.07437 6.23195 6.13276 5.82163 5.51799 5.396875 6.23219 5.530705 6.34551 7.379405 6.06302 7.60206 7.60206 6.08606 6.86616 6.47751 7.11219 5.66316 6.83791 7.41187 5.526255 5.49759 6.95295 5.52414 5.732465 7.558215 6.4209 7.026725 5.325005 6.498425 7.427165 5.45626 5.56657 5.361645 5.41719 5.946165 6.101305 T2 Anthrapyrazole-derivative 355644 7.00512 6.39169 5.77794 6.84017 5.77712 6.97037 6.203435 6.94076 6.97265 7.61349 5.72135 6.414145 8 7.67888 6.707745 7.49058 7.513375 7.84972 7.02696 7.35973 7.388325 6.277415 6.61012 6.743755 6.61046 5.65573 6.40696 5.892325 5.96155 6.67747 6.15499 6.84731 7.50164 6.4845 7.58526 7.426935 5.82841 7.44165 6.8157 7.13873 6.23864 7.093945 7.035355 5.822635 5.791275 7.669445 6.2529 5.99834 7.21059 6.95503 7.40892 4.77179 6.25489 7.19385 6.01368 6.479675 6.03459 5.93287 6.54426 6.20892 T2 Bisantrene 337766 7.24278 6.781445 6.74721 6.57282 6.530675 6.887665 6.55998 6.94704 7.15786 7.54679 6.71701 6.914765 7.60206 7.07093 7.128855 7.09832 7.22888 7.15279 7.08203 6.346025 6.95166 7.04242 6.741825 7.15661 6.948305 4.78402 6.95105 6.782785 6.7455 6.47726 6.61256 6.767695 7.60206 7.07488 7.60206 6.93593 4.67023 7.09759 6.42391 6.10909 6.47606 7.032915 6.518165 6.047275 6.57706 7.13633 7.21816 6.45171 7.232515 7.04318 7.35452 3.94222 7.038855 7.13108 5.18294 7.11963 6.809455 6.90415 6.683595 6.61112 T2 Daunorubicin 82151 7.6018 7.26218 6.58208 7.18791 6.57608 7.18766 6.77042 7.14954 7.254545 7.240745 6.1612 6.44532 8.30103 7.627605 7.13677 7.40551 7.05513 7.57692 7.10699 7.18522 7.26399 7.09281 6.732855 7.6139 7.66457 6.103375 6.85337 6.747905 6.422155 7.24177 7.02184 6.82967 8.033835 7.362715 8.30103 8.30103 6.285415 7.44565 6.78539 7.017305 6.86563 7.57341 7.492955 6.39489 6.68602 7.44034 6.79955 6.665035 8.068485 7.57497 8.30103 5.207335 7.094955 7.006385 6.656925 6.81452 6.66057 6.77795 6.72565 7.18364 T2 Deoxydoxorubicin 267469 7.89985 7.33091 6.822015 7.39037 6.87176 7.42215 7.12442 7.47155 7.22459 7.98156 6.80166 6.837215 9 7.63139 7.48214 7.454515 7.2712 7.65327 7.30061 7.47685 7.46386 7.38131 6.99341 7.746485 7.67678 6.81018 7.05515 6.91739 7.16088 7.3565 7.33526 7.213125 7.83652 7.57388 8.64769 8.64382 6.72469 7.53571 6.86668 8.03908 6.91438 7.56089 7.80854 6.74148 6.93724 7.44935 6.96184 6.93196 7.934355 7.71594 8.270715 5.56212 7.14851 7.61634 6.633995 6.76007 6.88146 6.96411 6.97389 7.22919 T2 Doxorubicin 123127 7.30854 7.148295 6.51598 7.130645 6.47513 6.94782 6.631485 7.149525 7.19364 7.039205 6.19914 6.28299 8.60206 7.228665 7.026575 7.21116 7.03994 7.27969 6.9707 6.99374 7.124235 6.676575 6.56379 7.11139 7.0465 5.84093 6.504315 6.29347 6.13308 6.81925 6.89075 6.587055 7.39052 7.028795 8.00555 7.78565 6.12831 7.02061 6.7949 6.75929 6.549425 7.22922 7.12049 6.2593 6.55784 7.30286 6.57343 6.145145 7.250365 7.269345 7.72946 4.73697 6.57545 6.90791 6.33764 6.523315 6.50742 6.52207 6.45805 6.96347 T2 Etoposide 141540 5.69324 4.997045 4.83747 5.3915 4.74434 5.426545 5.99769 5.61028 5.42365 5.66868 4.72 4.13385 6.496605 5.88986 5.377145 5.473435 5.133245 5.7157 5.31629 5.504175 5.76125 4.76774 4.91635 4.955575 5.24646 4.78153 4.81435 4.484695 3.80608 5.18567 4.58669 5.06078 6.279545 5.11107 6.6539 6.51567 4.47409 5.49062 5.0291 5.663555 4.81436 5.94798 6.236885 5.56573 4.50391 5.61243 4.59834 4.75481 6.51662 5.73197 5.94109 4.21581 6.203675 6.05452 5.75726 6.088605 4.5491 5.94281 5.60674 6.076605 T2 Menogaril 269148 6.0027 5.96324 5.635175 5.95207 5.26135 6.09718 6.00549 5.989465 5.95572 7.01715 5.1423 5.60673 7.73575 6.763995 5.98964 6.4099 6.208145 6.42039 5.99235 6.53014 5.95054 5.68428 5.64656 6.22147 6.189505 5.76764 5.73741 5.631805 5.29211 5.978985 5.67722 6.300215 6.77571 5.98182 7.92446 7.289825 5.75184 6.2702 5.909985 6.95871 5.78374 6.56701 6.965575 5.12728 4.97766 6.17924 5.66535 5.567745 6.86791 6.29231 7.03168 4.94986 6.24956 6.43232 5.60913 5.251125 5.76073 5.67923 5.71374 6.0452 T2 Mitoxantrone 301739 7.56475 6.91978 6.38716 7.30392 6.348535 6.98249 6.957645 7.480275 7.3327 7.96278 6.85691 6.56788 8.60206 7.7516 7.51577 7.609245 7.90948 7.98727 7.4243 7.66295 8.03055 6.700765 6.63497 7.29866 7.16512 6.509 6.37426 6.337805 6.315675 7.38203 6.63765 7.17806 8.14177 7.00007 8.60206 8.11662 6.57193 8.29657 7.259845 8.11674 7.141755 7.69552 7.97673 6.37817 5.683625 7.57021 6.632345 6.54779 7.77384 6.57926 8.60206 5.41161 6.954635 7.466075 6.64297 7.22234 6.326905 6.50333 7.14945 7.254 T2 Oxanthrazole (piroxantrone) 349174 6.05404 5.840685 5.59283 6.00831 5.39656 5.8978 5.47152 6.052295 5.88897 6.38671 5.485705 5.46476 6.81304 6.46943 6.262785 6.344125 6.12376 6.23615 5.865035 6.09148 5.98014 5.49089 5.43538 5.78505 5.958605 5.24613 5.53086 5.333225 5.41166 5.7831 5.569375 5.76198 6.28417 5.92331 6.59784 6.53557 5.155905 6.526355 5.63076 6.10528 5.551425 6.14093 6.162425 5.183095 5.2141 6.38202 5.73355 5.29314 6.2305 5.91928 6.321435 4.54831 5.403915 5.945335 5.384415 6.13513 5.513035 5.44589 6.15812 5.53141 T2 Teniposide 122819 6.76244 6.18809 6.010515 6.407825 5.828735 6.33676 6.23591 6.53179 6.24462 6.80984 6.07452 5.33735 7.901195 6.858515 6.92574 6.720035 6.24627 6.78019 6.324875 6.78951 6.5279 5.84531 6.203765 6.04541 6.438285 5.761345 6.134605 5.81005 5.26794 6.21827 5.599305 6.17124 7.2667 6.15513 7.77599 8.58685 5.38403 6.48476 6.287335 7.05074 6.155715 6.59096 6.63749 5.83345 5.66774 6.09525 6.38913 5.75264 7.27573 6.83111 7.29338 4.60206 5.921125 6.455605 5.8649 6.38031 5.904725 5.98971 6.27722 6.79117 T2 Zorubicin (Rubidazone) 164011 7.131035 6.85852 6.34938 6.5627 6.24076 6.66285 6.627235 6.60845 6.648955 6.66449 6.10595 6.00856 7.53109 6.73285 6.89991 6.795165 6.531105 6.76567 6.5638 6.75029 6.528365 6.194595 6.264095 7.069255 6.89671 5.65309 6.39596 6.26806 5.848225 6.53058 6.599195 6.30665 7.20051 6.58599 7.39564 7.90309 5.59281 6.85165 6.38144 6.80482 6.611405 7.2582 7.082825 6.287095 6.28564 6.85847 6.31496 6.15368 7.25364 6.769865 7.257565 4.70564 6.678005 6.88973 6.26221 6.457075 6.44057 6.470305 6.51685 6.7218 Pi L-Asparaginase 109229 -0.06403 -1.23499 -0.04615 -0.821735 0.06238 -0.45346 -0.78553 -0.52028 -0.04036 0.022665 0.22549 -0.135085 -0.05195 0.18998 -0.51567 -0.64313 -0.81817 0.02818 -0.41212 -0.03227 -0.252295 -0.47529 -0.44004 -0.50415 -0.65746 -0.570225 -0.2058 -0.994275 -2.39794 0.11218 -1.20162 -0.22938 1.60206 -0.76131 1.60206 0.476895 -0.69544 0.41564 0.288645 0.015255 0.03518 -0.16797 -0.5782 -0.67837 -0.54362 -0.06868 -0.42062 -0.05137 0.39936 -0.27729 -0.12563 0.50584 -1.33751 -0.60297 -0.92963 -0.86781 -0.96131 -0.879715 -1.3059 -1.07733 Db Cyanomorpholinodoxorubicin 357704 10.84908 9.83001 10.1551 10.50587 9.82733 10.33113 10.10592 10.91147 10.35504 10.30187 9.46163 9.98104 11.00141 10.73411 10.031415 10.09409 10.637765 10.628135 10.219545 10.97752 10.45217 10.442465 10.08072 10.440935 10.021635 10.21509 10.26207 10.44516 10.37119 10.35773 10.0775 10.13344 10.44776 10.246255 10.566465 10.097 10.45416 10.46166 10.44393 10.43861 10.51841 10.594935 10.59654 9.43329 10.003895 10.57738 9.74499 10.12982 10.44465 10.432335 10.516395 10.0541 9.96027 10.237265 10.02469 10.22934 10.11606 10.073075 10.37642 10.045995 Db Hycanthone 142982 5.262385 5.236625 4.82198 4.88368 4.83803 4.90695 NA 4.83492 5.06728 5.12124 4.79356 5.03142 5.496635 4.92612 4.99963 4.85796 4.886695 4.93798 4.99921 5.15378 5.080795 5.15503 5.02704 5.37369 5.263835 5.03627 4.945715 5.049555 5.185415 5.20532 4.86532 4.87649 5.343035 5.45475 5.501385 NA 5.20041 5.1327 5.21519 5.52113 5.30227 NA NA NA 5.05584 5.00024 5.378 4.96578 5.010635 5.00824 5.2543 5.14104 NA NA NA NA NA NA NA NA Db Morpholino-adriamycin 354646 8.244845 7.770935 7.72914 7.80163 7.4387 7.59132 7.4189 8.01764 7.703335 8.12208 7.31382 7.929945 8.43911 7.569745 7.53879 7.598925 7.87992 7.79526 7.58401 7.80823 7.81615 7.96333 7.700145 8.51673 8.09443 7.7666 7.53297 7.62453 7.65615 8.127245 7.59795 7.362705 7.71078 8.04606 8.02399 8.30531 7.63912 7.69669 7.838 7.997025 7.65444 7.97843 8.32577 7.22451 7.6269 7.97991 7.82507 7.38298 7.628215 8.019225 7.53597 6.9612 7.47166 7.261715 7.33294 7.541715 7.312325 7.45462 7.44885 7.243255 Db N-N-Dibenzyl-daunomycin 268242 5.38113 4.61951 4.30103 4.39983 4.30103 4.56959 4.32186 4.72551 4.690095 5.35465 4.30103 4.68248 6.0147 4.33494 4.30103 4.62847 4.30103 4.870335 4.8841 4.610005 4.417425 4.75286 4.30103 5.6963 5.328645 5.010035 4.71439 4.33242 4.54782 5.16044 4.92082 4.30103 5.18347 5.42854 5.90498 6.02506 4.754265 4.96223 4.30103 5.20853 4.30103 5.60406 5.662085 4.73931 4.32087 4.85979 4.62398 4.30103 4.72243 5.1943 4.84918 4.8828 4.94431 4.77195 4.72874 4.746045 5.38745 4.7624 4.56124 5.00782 Db Pyrazoloacridine 366140 6.75499 6.09569 6.101615 6.3719 5.99227 6.374275 6.60971 6.27546 6.73938 6.60971 6.17871 6.52215 6.76886 6.63408 6.433625 6.478625 6.474365 6.69896 6.503 6.443605 6.61759 6.89125 6.53336 7.20412 6.97465 6.72166 6.53419 6.266285 6.44452 6.6902 6.511235 6.36887 6.80832 6.65567 6.72561 6.84932 6.599415 6.91245 6.15754 6.57082 6.63812 7.17106 7.20412 6.494805 5.81781 6.482145 6.88037 6.219645 6.44368 6.57561 6.5568 6.679805 7.08318 6.50141 6.57927 6.33357 6.812575 6.828145 6.01725 6.216355 Di 5-6-Dihydro-5-azacytidine 264880 5.66928 4.96889 6.0239 4.30717 4.28634 4.00348 5.160745 4.75388 5.22352 4.79685 3.30913 5.02644 5.15567 3.84673 3.163785 3.81391 4.533675 4.58363 4.86293 4.371665 4.68442 4.33305 4.4495 4.82182 4.83114 5.265635 4.86855 4.392135 3.90438 3.31047 5.222235 4.034545 5.03536 5.68864 5.10195 5.34796 3.801715 3.22739 5.23345 3.95728 5.05743 5.178715 6.08363 4.93792 4.36199 5.24568 3.81245 3.890955 6.11027 5.78484 4.96043 3.13383 3.382995 3.776345 3.986165 4.61123 5.178135 5.1798 5.04362 4.933975 Di alpha-2'-Deoxythioguanosine 71851 4.622035 3.64714 3.76623 3.503095 2.52703 3.72424 4.04288 4.25539 3.79296 3.60128 3.59563 3.41642 4.07296 3.868585 3.49773 2.78076 3.36282 3.50701 3.65685 3.94538 3.71921 3.77472 3.911365 3.93725 3.597105 3.84661 3.70449 3.942565 3.90514 3.92591 3.7027 4.25192 4.63924 4.18072 4.33 4.43824 3.857615 3.56477 3.668 3.94547 3.71515 3.923245 3.752645 4.027715 3.586495 3.397955 3.75874 3.850535 3.78296 4.55772 3.96448 4.28146 3.828015 4.09204 3.602615 3.325165 3.69371 3.72287 3.09968 3.94111 Di Azacytidine 102816 6.41456 6.07142 6.60206 5.80718 5.89531 5.55158 6.337855 6.350935 6.10684 6.02586 5.53694 6.07498 6.60206 6.314215 5.54715 5.6732 5.67486 6.02682 5.88541 5.83877 6.05805 6.00347 6.16641 6.60206 6.120245 5.98267 6.07927 6.08507 6.26851 6.24478 6.16516 5.649375 6.28435 6.1969 6.018515 6.10766 6.12698 6.22586 6.02143 6.601415 6.21027 6.00134 6.366145 5.932945 5.76244 6.05206 6.17231 5.43025 6.60206 6.60206 6.063835 5.93718 6.18234 6.548945 6.37146 6.09298 6.245345 6.18254 6.14906 6.60206 Di beta-2'-Deoxythioguanosine 71261 6.4486 5.915405 5.89644 5.49626 5.03742 5.94311 6.44944 6.42899 6.10945 5.428695 5.979 5.24761 6.2561 6.21888 5.638575 4.08095 5.419325 5.04798 6.12856 6.09513 6.174795 5.980055 5.836725 6.292585 5.79937 5.86085 5.7521 6.13194 6.16372 6.2782 5.3426 6.296725 6.551545 6.26302 6.43124 6.90309 6.122965 5.888745 5.40616 6.24642 6.197005 6.51394 6.0229 6.440945 5.35516 4.88543 5.68949 6.245085 5.6833 6.37419 6.26962 6.22943 6.15476 6.422305 6.204455 5.08475 6.31958 6.37929 5.39462 5.55614 Di Thioguanine 752 6.71275 5.91548 6.01804 5.409005 4.988395 5.98033 6.20088 6.18824 6.10444 5.362195 5.77759 5.02292 6.148805 6.08288 6.12792 4.09654 5.905835 5.3366 5.95357 5.94831 5.972545 5.9297 6.030315 6.162045 5.84336 5.98433 5.7839 6.09744 5.90647 6.0991 5.22764 6.178145 6.86849 6.37991 6.63393 6.8695 5.910755 5.899385 5.09093 6.20771 6.08942 6.06665 5.76478 6.013345 5.7701 5.34066 5.78964 6.13355 5.99786 6.36694 6.13484 6.11171 5.7606 6.09612 5.755775 5.3236 6.04005 6.062175 5.56788 5.845465 Df Aminopterin 132483 7.926655 4 4 6.34467 4.91942 6.50431 7.78835 7.299835 5.77764 5.87591 5.088975 6.26524 7.20681 6.12842 4.83983 6.65365 4 7.04764 6.43925 7.01098 5.22099 7.681785 6.2906 8 7.758435 7.36957 6.57485 5.12234 5.003645 7.13701 7.22724 4.33638 7.1735 8 7.128505 8 6.177085 6.244045 6.35862 7.506805 4 8 7.58153 5.29123 5.24609 4 5.331685 6.03285 4 4 6.99785 7.10222 8 7.23128 4 4 8 8 4.47797 4 Df Aminopterin-derivative 134033 8 6.41623 4.58074 6.7401 6.25195 6.73604 7.12884 7.04935 6.31591 7.46148 5.196655 7.094115 7.48476 6.76668 4.05844 6.35921 4.6809 7.35682 7.27722 7.15371 6.58496 7.846315 6.66129 8 7.98509 7.7362 7.08352 6.14975 4 7.31348 7.24456 5.49349 7.3094 8 7.758385 NA 6.54305 6.52177 6.83884 7.056975 4.18119 8 7.59677 7.09451 6.58637 4.665325 6.06484 6.72489 NA 4.86861 7.23762 7.54937 8 NA 4 4 8 8 4.58779 NA Df Aminopterin-derivative 184692 8 6.06383 4 8 4.71563 8 8 8 6.24746 8 4 5.924055 8 6.573555 5.19136 5.69915 5.15123 7.269165 8 7.19565 8 8 7.38071 8 8 8 7.133035 4.31154 4 8 8 4 7.894255 8 8 8 6.38114 8 5.55282 8 4 8 8 4.815 5.30082 4 4.77665 5.22011 7.5014 6.60625 8 7.69863 8 7.90258 4 NA 8 8 4.59528 4.68818 Df an-antifol 623017 8 4.27273 4 7.735535 8 8 NA 8 8 8 8 NA 8 7.69931 8 7.69462 5.844125 8 7.39793 8 8 8 8 NA 6 8 8 7.803365 5.117425 8 8 4.40306 7.159655 7.615995 7.7134 NA 6 7.101855 4 8 4 NA NA NA 6 4 6 6 8 8 8 6 NA NA NA NA NA NA NA NA Df an-antifol 633713 9.42818 8.70685 7 8.23854 8.33382 8.397015 7.646635 8.89029 7.79661 8.42189 7.65588 7.647595 9.34686 8.34815 7.56188 7.6663 7 7.843285 8.737335 8.47828 8.461265 8.992485 8.87953 9.5523 9.0627 8.98023 8.52683 7.17032 7 8.822955 7.603615 7.29672 8.82937 9.41951 8.45191 9.37231 8.274165 8.643795 7.66624 8.650175 7.53395 9.26763 8.74189 7.50825 7.80892 7 7.11642 8.706825 9.30989 7 8.44011 8.56461 7 8.02032 7 7 8.50679 8.89791 7 7 Df Baker's-soluble-antifolate 139105 7.33497 6.28173 4 8 5.512875 7.78269 7.0862 8 7.16591 8 4.035255 5.961995 8 5.659115 4 6.59973 6.034465 7.21896 7.45727 6.35302 7.575035 7.24076 5.375 7.42637 7.11403 4.43668 7.26421 4.9127 4.07078 6.02158 8 4 7.293235 8 7.36121 7.692485 4.000415 8 4.783905 4.50267 6.46748 7.388725 5.39983 4.414285 5.16988 4 6.25555 6.1617 7.39568 6.50146 7.563255 4 8 7.711985 4 4 7.61881 7.64842 4 4.874435 Df Methotrexate 740 9 5 5 7.20081 5 7.210485 7.41257 8.21716 5 8.180425 5 6.19167 8.358565 7.92279 5 5 7.10671 7.30381 7.315535 8.05058 7.86997 7.693035 7.02485 8.737435 7.147115 8.30274 7.65577 6.16131 5 7.313005 7.029055 7.00732 7.82777 8.50103 7.47463 8.41136 7.21865 8.175615 5.67008 8.279305 5.48814 7.946715 7.782095 5 5 5 6.23945 7.72072 7.833235 7.228875 7.87123 7.40719 8.762965 7.645565 5 5 7.58501 8.057845 5.22826 5.73482 Df Methotrexate-derivative 174121 9.30444 7 7 8.20389 7.08396 8.40302 8.43676 9.17605 7.16636 8.41607 7 7 9.3006 7.58677 7 7 7 8.22849 8.42881 8.38419 8.47891 9.00786 8.83944 9.35574 9.16642 8.81522 8.43389 7 7 8.02564 8.01409 7 9.37356 9.53297 8.32193 8.601565 8.34814 8.36548 7.27922 8.29104 7 9.15484 8.27356 7 7.46258 7 7.07734 7.733445 9.360615 8.117415 8.78663 8.4029 9.32014 8.0275 7 7.007635 8.608385 9.07879 7.036035 7 Df Trimetrexate 352122 9.578025 9.15876 6 9.751365 8.54058 9.21564 9.54902 9.6242 8.445335 10 7.12288 7.70434 9.832975 8.92569 7.632325 7.68411 6.7433 9.288285 9.16115 9.509865 9.62218 9.70524 8.07956 9.75927 9.434475 9.35692 8.72695 7.51412 6.4375 9.16511 9.52762 8.13727 9.5366 9.93702 9.56955 9.38526 8.52181 9.380815 8.13974 8.48566 8.30609 9.09443 9.38537 8.01018 8.003005 6.58333 8.49672 7.54668 9.08474 8.37171 8.8261 7.74232 9.36161 9.1313 6 6.61976 9.41164 9.702545 6 7.103445 Dr Guanazole 1895 2.42692 2.107605 2 2.400205 2 2.312995 2.485515 2.54983 2 2.37942 2 2 2.50988 2.30696 2.12437 2 2 2.40585 2.21332 2.71993 2.614085 2.34604 2.181035 2.18623 2 2 2 2 2 2.412235 2 2 2.67978 2.008095 2.49546 2.43929 2.112105 2.30725 2.34751 2.36494 2.119765 2.58616 2.72003 2 2 2.09265 2 2.29356 2.83147 2.4862 2.46959 2.593845 2.020165 2.247525 2 2 2 2.01818 2 2 Dr Hydroxyurea 32065 3.132375 2.99799 2.60206 3.28275 2.60206 3.11337 3.251775 3.51307 3.161265 3.27833 2.60206 2.60206 3.437945 3.01482 3.042795 2.75592 3.079695 3.22669 3.28494 3.34084 3.44203 3.32759 3.06196 3.015655 2.93966 3.11303 3.054405 2.90703 2.60206 3.27225 2.863605 2.70457 4.34364 3.06002 3.748215 3.64461 3.29104 3.113275 3.10996 3.50609 2.93662 3.57237 3.9438 2.60206 2.6999 3.09308 2.70479 3.236895 4.812635 3.65985 3.417025 3.40762 3.03652 3.09959 2.60206 2.84771 2.68004 2.71005 2.75423 2.90398 Dr Pyrazoloimidazole 51143 2.530925 2.554475 2 2.86021 2.08578 2.64052 2.73587 3.278255 2.42043 2.73216 2.519 2.35323 2.8376 2.423925 2.31896 2.34989 2.47365 2.79036 2.551275 3.37329 2.99364 2.610275 2.412115 2.493355 2.34619 2.39815 2.49816 2.32535 2.12674 2.77691 2.136165 2.25393 3.50623 2.42293 3.33369 3.04873 2.60847 2.663325 2.7241 3.36075 2.68929 3.02022 3.335395 2 2.177695 2.30808 2 2.43236 3.38347 2.81238 2.895575 3.11314 2.29612 2.51147 2 2 2.404955 2.36529 2.31468 2.48243 Ds Aphidicolin-glycinate 303812 5.60448 4.22609 4.173975 4.922785 4.205645 5.392185 5.3408 6.082095 4.20099 5.756325 4.25742 4.16175 6.59204 5.512915 4.745855 4.2853 4.504225 5.672265 4.96995 6.39848 5.89215 5.11236 4.20774 5.74237 4.29038 4.274935 4.241925 4.15334 4.07502 5.61733 4.29384 4.205275 6.11453 4.72732 5.79659 5.779865 5.37017 5.06871 5.15817 6.14609 5.103735 5.7903 6.78618 4.13271 4.226135 4.93409 4.25164 4.6692 6.64649 5.53829 5.438285 5.34158 5.47976 5.8151 4.194795 4.140595 4.45874 4.24606 4.202405 4.350955 Ds Cyclocytidine 145668 6.18865 5.749405 3 5.05939 5.33251 6.14469 6.56885 5.58418 3 6.54419 3 3 6.936 6.4417 4.62911 4.69032 3.03125 5.03438 5.08077 4.63978 4.48689 3.18939 3 6.42804 5.04706 3.536135 3 3 3 6.117885 3 3.92886 7 4.050105 7 7 5.31183 5.4426 4.72592 5.54746 3.51924 6.19033 6.51505 3 4.21226 3 3.3125 5.15468 5.91855 3.32738 6.225125 5.621135 5.7793 5.64545 4.131865 3 4.61338 5.190905 3 3 Ds Cytarabine (araC) 63878 6.72091 5.04772 3.30103 4.97543 3.30103 6.663955 6.840925 5.904075 3.30103 6.896835 3.30103 3.30103 7.28399 6.86757 5.29016 5.50398 3.30103 5.44811 5.61782 4.92001 4.523925 3.30103 3.30103 6.79239 4.17941 3.30103 3.30103 3.30103 3.30103 6.174885 3.30103 3.30103 7.30103 3.79032 7.30103 7.07069 5.57136 5.70015 5.175005 6.01952 3.30103 6.371995 6.6703 3.30103 3.30103 3.30103 3.30103 5.04239 6.7785 3.30103 6.909695 5.9022 3.64191 5.666245 3.30103 3.30103 3.805865 5.34402 3.30103 3.30103 Ds Floxuridine (FUdR) 27640 7.64789 5 5 6.72466 5.690805 6.50007 6.75048 7.4939 5.667475 8.01479 5 6.306185 9 7.471205 6.07354 5 7.27622 7.04903 7.85958 7.42273 8.51986 5.80968 9 7.04162 5 5.446575 5.00179 5.374685 5 6.8824 5.55271 5.71356 8.16918 6.073315 7.36838 7.47958 7.113995 6.875845 5.78971 7.35517 5.376155 7.244045 7.401085 5.346005 5.31585 5 5.766145 5.01651 6.724155 5.789585 8.41101 5.86844 6.56608 6.592635 5.18272 5 5.31103 5.87817 5.958685 6.12773 Ds Fluorouracil (5FU) 19893 5.17358 4.76348 3.14811 4.89205 4.62036 4.96418 4.455535 4.87203 4.47167 5.71142 3.08975 4.53755 5.957655 4.91329 3.83138 3.943585 3.74457 4.31325 4.27906 4.26307 6.11428 5.14435 6.180835 5.347575 4.63865 5.194845 4.91658 4.38285 4.06634 4.80855 4.80629 3.60069 4.61415 4.797865 4.90571 5.402675 5.18378 4.6469 5.25616 5.37944 4.18324 4.909025 4.93894 3.39545 3.93559 3.56937 5.12169 3.574025 4.92005 5.35116 5.78298 4.63276 4.3777 5.11768 2.98539 3.637935 4.92597 5.01712 3.84829 4.20051 Ds Ftorafur 148958 2.892805 2.54412 2.54356 3.45876 3.069 3.026945 2.75174 2.45055 2.30103 3.160145 2.30103 2.30103 3.43344 2.59041 2.30103 2.314675 2.30103 2.30103 2.471535 2.30103 3.29871 2.55372 2.74725 2.8318 2.82299 2.94298 2.73607 2.685145 2.386155 2.51692 2.615425 2.30103 3.02591 2.46324 2.30103 3.47247 3.03267 2.531955 2.30103 2.684925 2.95313 2.58514 2.488045 2.597255 2.40027 2.33301 2.89025 2.315245 2.9701 3.19385 3.240585 2.490395 2.5453 3.06055 2.30103 2.31318 2.86814 2.952735 2.3982 2.47403 Ds Thiopurine (6MP) 755 6.50511 5.49234 5.4628 5.06814 3.12494 5.45534 6.31598 5.696065 5.715275 4.51592 3.42245 5.22851 5.28952 5.69637 5.45374 3.84429 5.05263 4.9104 5.417585 5.41256 5.59214 5.38249 5.49612 5.58918 5.233875 5.37636 5.19386 6.2343 5.32135 5.57177 5.056945 6.1041 5.852585 6.511005 5.784585 5.919895 5.37469 4.54161 4.251965 5.60413 4.71168 5.74014 5.251665 5.61536 5.21136 4.02661 5.38419 5.33129 5.60266 5.79485 5.73844 5.494315 5.40044 5.67505 5.14387 4.84125 5.724725 5.716865 3.73744 5.624095 Rs Acivicin 163501 5.77186 5.53145 5.01723 5.61696 5.38153 5.364635 5.429355 5.536165 5.26537 6.060655 5.7643 5.1327 6.35303 5.731335 4.615605 5.36635 4.78846 5.6124 5.93384 5.883065 5.40708 6.053205 5.447805 6.171725 6.0526 6.09737 6.20903 5.49418 5.247035 5.620425 6.18311 4.888495 5.87239 5.54969 5.642615 6.1277 5.2777 5.33932 5.18978 5.52493 5.170995 5.43252 5.88543 5.48021 5.304565 5.209365 5.23901 5.21693 5.41132 5.41195 6.1825 5.33187 5.77048 5.642985 3.15132 5.48374 5.409395 5.414305 5.13073 5.17816 Rs Dichloroallyl-lawsone 126771 5.734455 4.93593 4.47787 5.244375 4.53049 4.68857 4.53223 5.50025 4.93919 5.3694 4.32057 4.49998 5.85011 4.91386 4.386455 4.923625 4.385565 5.65223 4.65737 5.50286 4.9351 5.465295 4.52533 5.88475 4.944725 6.11214 5.166385 4.825725 4.835575 5.27107 5.150885 4.389425 5.623065 5.75954 5.76818 5.97673 4.667065 4.83481 4.42622 4.720575 4.4694 5.254925 4.918905 4.43224 4.6317 4.4623 4.58549 4.36643 5.701865 5.69263 5.04012 4.596535 5.11897 4.665735 4.896275 4.36419 4.77248 4.80301 4.743845 4.64153 Rs DUP785 (brequinar) 368390 7.012605 4.7173 4.24016 6.025445 4.274685 4.33219 5.30897 6.74162 5.68278 6.570125 4.41729 4.237905 6.77327 6.61459 4.441995 5.94367 4.095465 6.650105 6.80305 6.90164 6.95128 6.42179 4.645325 7.08579 6.41149 7.30103 6.49457 5.63806 5.11752 6.66487 6.411945 4.1664 6.67233 6.967275 7.244195 6.36971 5.88314 5.82773 4.11638 6.50603 4.93075 6.944125 6.79082 4.23141 4.93957 4.57458 6.6854 4.042585 6.48854 6.56796 6.62721 5.79756 6.7825 6.453425 4.93628 4.680395 6.4308 6.53224 4.24132 4.43324 Rs L-Alanosine 153353 6.50183 4.178365 3.97916 5.87325 4.55746 5.74004 4.7333 5.499625 4.558145 6.696065 4.37261 4.930235 6.21104 5.09236 3.92262 6.12219 4.13303 6.16836 5.1102 5.305945 4.995345 4.93298 4.86268 6.01394 4.76088 5.69211 6.477725 4.86278 4.70196 4.969195 6.51392 4.23751 5.024475 4.84449 4.70264 4.95236 5.79582 4.76705 5.42076 5.34162 4.5117 5.821585 5.55535 4.6448 4.27407 4.21586 4.589695 5.340805 5.054215 4.72634 5.97621 4.68916 5.406045 3.917015 3.30103 4.92065 5.218415 5.162335 5.03814 3.77851 Rs N-phosphonoacetyl-L-aspartic-acid 224131 4.262325 2.43266 2.137205 4.09128 3.72188 2.40465 3.53903 4.09584 3.00622 4.35972 2.77004 2.14565 4.50995 3.53859 3.19879 4.273235 2.14318 4.41944 4.02261 4.40909 4.117165 3.788 2 4.66163 3.524095 3.79355 4.025745 3.26701 2.70757 4.062605 3.51502 2.007075 3.25341 4.149625 3.53773 3.642325 3.13094 3.145525 2.59499 3.46228 3.5824 4.35865 3.42173 3.051485 2.36859 2.53815 3.24 2 3.625495 3.597755 3.51706 3.1234 2.98354 3.06925 2.88859 2.387115 4.424705 3.89032 2.493135 2.38079 Rs Pyrazofurin 143095 6.30103 3.326495 4.12461 4.07986 3.21584 4.90858 4.190915 5.229 4.10501 6.30103 5.05269 5.87538 6.30103 5.84099 4.53377 6.30103 3.995415 6.07484 5.57592 6.30103 4.85438 6.23666 4.481425 6.30103 6.30103 6.30103 5.20157 4.66584 4.299365 6.30103 6.2095 3.83487 6.30103 6.30103 6.30103 6.30103 5.49061 5.993595 4.14119 6.30103 5.267435 6.30103 6.30103 3.92181 2.77237 3.85711 5.22392 3.79381 6.30103 6.30103 6.13585 5.539855 5.76451 6.30103 5.078935 4.04065 4.777135 5.61102 3.739675 4.95232 TU Colchicine 757 8 7.96804 8 8 8 7.91015 7.839285 8 8 7.36606 4 7.45196 7.61908 7.58254 8 7.49136 8 7.518225 7.35616 7.828645 8 7.59294 7.78318 7.78725 8 6.86853 8 7.80635 4.238885 7.601435 7.63886 7.71327 8 8 7.59855 7.64032 6.3833 7.28378 7.537185 7.11197 7.93464 7.34018 6.508095 4 4 7.51971 8 4.23913 8 8 7.942935 6.31205 7.634855 6.18133 6.462165 NA 8 8 7.685975 4.1059 TU Colchicine-derivative 33410 8 7.69209 8 8 4.68783 8 8 8 8 8 4.60106 8 8 8 8 7.81179 8 8 8 8 8 8 7.85279 8 8 7.832135 8 8 4.820535 8 8 7.80667 8 8 8 7.61791 7.18312 8 8 7.623 8 8 7.35572 6.88196 7.62217 7.54204 8 5.41292 8 8 8 6.75706 7.80217 7.58687 7.96591 7.900315 8 8 6.39816 4.23409 TU Dolastatin-10 376128 9.46744 9.556235 9.86686 10.140805 9.40343 9.39299 9.54391 9.41605 9.88483 9.58517 9.345225 9.629835 9.918135 9.42366 8.991865 9.241215 9.53097 9.40405 9.25098 9.637445 9.57381 10.41775 9.41914 9.66765 9.718245 9.27939 10.35187 10.10561 8.931315 9.352495 8.99453 9.67338 9.61027 9.940065 9.435395 10.39973 8.1525 9.30591 9.514045 9.61565 9.50149 9.391055 9.1665 8.630255 9.618105 9.57971 9.83628 9.22508 10.18281 9.48221 NA NA NA NA NA NA NA NA NA NA TU Halichondrin B 609395 9.22689 9.18455 8.91911 9.60708 8.58832 8.82006 8.87605 9.33951 9.656865 8.76299 8.3016 8.85276 9.393545 8.88249 8 8.6299 9.415965 9.08609 8.38703 9.39814 9.211115 9.4252 8.685585 9.294985 9.31691 8 9.32385 9.54633 8.073185 8.618705 8.755395 8.576215 9.30166 9.349545 9.12667 9.29565 8.23487 8.463395 8.968825 9.297785 9.22981 8.748955 8.371395 8.14196 9.38587 8.62528 9.26606 8 9.640545 9.11584 NA NA NA NA NA NA NA NA NA NA TU Maytansine 153858 8.89226 7.92825 7.75543 8.67346 7.62191 8.28824 8.02157 8.1926 8.54702 8.11158 8.07762 7.857365 8.53303 8.43465 8.53999 7.967225 8.35101 8.23584 8.22889 8.42955 7.80326 7.857455 8.56881 8.057705 8.29415 8.49655 8.06568 8.38744 8.16592 8.42933 8.50536 8.51737 8.54954 8.47066 8.50724 8.56059 7.940225 8.173215 8.14981 7.91826 7.92195 7.88972 8.24989 7.65706 8.118 8.294765 8.0382 7.84928 7.95684 8.39787 8.411045 8.22242 8.53438 8.03179 8.222765 8.23925 8.00668 7.96357 9.67809 8.122745 TU Trityl-cysteine 83265 6.06521 6.120735 6.38804 6.31625 4.87366 5.96167 6.50906 6.20064 6.41348 6.17539 6.22188 6.352045 6.35499 5.9125 4.87024 6.14242 6.09998 6.326195 6.01027 6.51686 6.46467 5.536335 6.29679 6.37742 6.25722 6.182535 6.194725 6.123715 5.36499 6.13494 5.84148 6.229575 6.32614 6.28903 6.11597 6.41318 4.66989 6.07724 5.93825 5.838735 6.34543 6.25772 4.78876 4.69146 6.06934 5.28722 6.311795 4.82797 6.36298 6.34543 6.33946 5.308455 6.15714 5.152135 6.4022 6.23198 6.66922 6.41196 5.93241 6.2413 TU Vinblastine-sulfate 49842 9.60206 9.60206 9.52556 9.60206 9.15739 9.504695 9.48267 9.60206 9.60206 8.793 8.00402 9.14282 9.60206 9.590345 9.064565 9.15317 9.60206 9.60206 9.13841 9.60206 9.60206 9.60206 9.21101 9.60206 9.60206 7.55309 9.60206 9.60206 6.405 8.89731 8.9645 9.60206 9.46722 9.60206 9.54935 9.60206 6.83573 9.11524 8.6368 8.29125 9.20294 9.36049 8.03202 7.77269 9.49692 9.31316 9.60206 5.603955 9.60206 9.48665 9.60206 6.559005 9.60206 9.60206 9.26707 9.60206 9.60206 9.60206 9.60206 5.60206 TU Vincristine-sulfate 67574 7 7 7 7 7 7 7 7 7 7 6.77781 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 6.12865 7 7 7 7 7 7 4.73333 7 7 7 3.97224 7 7 7 5.9849 7 7 7 7 7 7 7 3.68243 TU Taxol (Paclitaxel) 125973 7.5404 7.314775 7.2204 7.94079 7.31826 7.461235 7.466845 7.55137 7.81547 7.407155 6.53323 7.39313 7.8351 7.2008 6 7.30643 8.20873 7.573635 7.53196 7.05661 7.713495 8.034785 7.55095 8.207 7.51153 6.281935 7.896925 7.54343 6 7.50907 7.45607 7.37271 7.48643 7.51623 7.47477 7.630825 6 7.423895 6.550935 6.2547 7.34341 7.34083 6.12428 6.62953 7.10235 7.296905 7.65835 7.43593 7.74642 8.300865 7.81158 6 7.40785 7.40306 7.225955 7.8056 8.3025 8.364925 7.424305 7.010545 TU Taxol analog 600222 5.89147 4.93667 NA 5.926925 5.25225 5.774245 5.95925 5.687895 NA 5.57666 4.730635 5.622395 6.34323 5.71705 4.89772 5.33702 5.5886 5.75162 5.349785 5.424265 6.21224 6.45442 5.7164 6.26611 6.01464 4.4147 6.15099 5.724295 4.1 5.38306 6.118355 5.6214 6.12767 6.173405 5.711465 4.96912 4.07642 5.7222 7.001475 4.04948 5.59471 5.372375 4.931815 5.00287 5.37645 5.951655 5.99085 5.78376 6.441375 6.46094 6.61223 4 5.636895 5.58614 5.924415 5.954145 6.814165 6.566815 NA 6.08473 TU Taxol analog 656178 6.0763 5.595465 6.434835 5.18157 NA 6.061215 5.58677 6.29385 6.196125 5.418845 5.250065 5.375645 5.99222 5.218195 4.64549 5.481415 6.29532 6.08248 5.401365 5.27445 6.3822 6.414895 5.7643 6.431185 6.34926 4.608065 6.253295 6.342795 4.04228 5.505035 5.72572 6.1152 6.342515 6.208165 6.11956 5.974615 4.33603 5.661485 5.23541 4.60529 4.60248 5.53806 4.29106 5.0701 6.164585 4 6.36278 5.40399 6.3868 6.28518 6.33429 4 6.05477 5.47463 5.37833 6.59804 6.74527 6.78302 5.89815 4 TU Taxol analog 658831 NA 5.396255 NA 5.722025 5.56943 5.43434 5.635085 5.446985 6.60979 5.139975 4.18855 NA 6.12148 5.29661 4.60888 5.30856 6.83448 5.78426 5.63449 4.67309 6.305565 5.922605 5.79462 6.28665 4.794465 4 5.91802 6.15123 4 5.197005 5.399305 5.51663 5.805155 6.01454 5.610665 5.61769 4.11966 5.451145 4.59289 NA 5.70302 5.307195 4.04983 4.19916 4 4 6.17695 4.684525 6.265795 6.313225 5.990745 4 5.89119 5.54032 4.17049 6.702675 6.69468 7.10817 5.58056 5.75534 TU Taxol analog 661746 7.10202 6.335975 6.84277 6.92968 6.44012 6.81908 6.849565 7.11943 NA 7.12352 5.991685 NA 7.45761 6.910775 5.61856 6.623465 7.015485 7.085375 6.794145 5 7.54977 7.556285 7.175155 7.697295 7.29741 6.53541 6.147885 6.91202 5.62368 7.187385 6.442095 6.380035 7.43458 7.443495 7.36928 6.772025 6.01217 6.840785 6.785845 6.28019 7.23806 7.06895 6.255875 6.52278 7.0986 6.0543 7.103215 6.78274 7.570335 7.627025 7.53775 5.8048 7.082675 6.574265 6.67724 7.7308 7.932655 7.877355 6.71268 6.93157 TU Taxol analog 664402 7.265545 6.78336 7.132735 7.36189 6.979965 7.125145 7.00777 7.31398 7.515 7.09151 5.72811 6.63526 7.01955 6.66792 6.27155 5.62906 7.25625 6.86448 6.775085 6.536875 7.232835 7.383 7.153675 7.491645 7.338405 5.85094 7.6548 NA 5 7.174795 7.321955 7.750785 7.40051 7.287215 7.343415 7.39269 6.40253 7.092745 NA 5.807515 6.7263 6.490065 5.47907 6.42017 6.89647 6.369365 7.352685 6.293635 7.74469 7.516335 7.50852 5 7.248065 6.97424 5.22706 7.31383 7.80047 7.657165 6.46598 5.866795 TU Taxol analog 664404 8.208255 7.87044 8.62128 8.59956 8.497555 8.494235 6.632685 8.3225 8.60832 8.19629 6.36887 7.51747 8.47619 7.655765 6.29416 6.21709 9 8.055935 8.31308 7.351755 8.691435 9 8.51807 8.77818 8.538725 6.262065 NA NA 5 8.260565 8.54469 8.364385 8.70283 8.74578 8.82827 8.766395 5.6058 8.281195 6.60758 6.423335 7.850495 7.422985 6.803375 7.41728 7.82412 7.41997 8.75 6.646395 8.954155 9 9 5.0648 8.551165 7.6339 5 8.74533 9 7.042845 6.60457 8.398675 TU Taxol analog 666608 7.051825 6.745645 7.440885 7.16436 6.878355 7.03956 7.3322 7.333705 7.28139 7.00068 5.27205 NA 7.15104 7.29553 5.64686 6.55464 7.22648 7.15991 7.62162 6.517305 7.47314 7.343235 7.3401 7.57632 7.51486 5.81272 7.291225 7.440555 6.074715 7.041195 7.33056 7.60493 7.542335 7.536945 7.578905 7.620735 5.62052 7.167195 6.33074 5.79757 6.66015 6.81474 5.82082 6.296255 7.08286 NA 7.10433 6.813805 7.97038 7.64124 8.014905 4.803875 7.25661 6.998325 7.32169 7.718145 8.002605 7.99388 7.092645 5.6651 TU Taxol analog 671867 8.08787 6.75261 7.09498 7.969075 5.751305 7.584135 8.140465 7.888135 8.03712 7.71344 4.90309 7.81966 8.118225 7.74308 7.83079 7.48713 6.39574 7.864615 6.693855 7.5684 8.52614 8.4748 7.5254 8.42185 8.198315 6.57152 8.136375 8.90309 4.990585 7.84177 8.459085 7.82128 8.30223 8.55988 8.32392 8.26608 6.071235 7.414055 NA 5.736505 7.479765 7.75407 6.383775 6.82186 7.59763 7.62815 7.885525 8.131325 8.90309 8.33964 8.58643 5.517735 7.77608 7.06217 7.370405 8.2614 8.646415 8.77122 7.872695 7.16919 TU Taxol analog 671870 6.19954 5.779485 5.62977 6.390805 5.80859 6.02285 6.260265 5.913765 6.254825 5.77012 5.131495 5.87962 6.090785 6.487305 5.670645 5.89586 6.11515 6.44204 5.92129 5.93626 6.3641 6.884815 6.10721 6.750685 6.45517 5.195265 6.786775 6.489 5.422505 5.85101 6.348265 5.99059 6.42486 6.67505 6.38617 6.86686 5.19049 5.67499 6.35327 5.272165 6.280415 5.785965 5.611635 5.56741 6.14448 5.76607 6.86818 6.073655 7.18058 7.043645 6.94807 4.60206 6.58941 5.73432 5.497815 6.65394 7.15514 7.199235 6.16301 4.60206 TU Taxol analog 673187 6.89012 6.92287 7.2255 6.93487 5.74095 6.38539 6.37589 6.558035 6.50957 6.285535 5.05583 6.26731 6.785115 6.17019 5.63388 6.463115 6.87259 6.90302 6.73234 5.839505 7.44779 7.40575 6.52751 7.228565 6.835085 4.820675 7.07868 7.21319 4.649055 6.563545 6.600735 6.54233 7.301065 7.10776 6.94286 7.091555 4.736575 6.512125 5.419385 4.84472 6.167145 5.93725 5.097605 5.0751 6.377145 6.36841 6.943155 6.476795 7.64407 7.72437 7.4682 4.60206 6.9207 6.170395 5.339255 7.21621 7.78192 7.898425 5.55091 5.689155 TU Taxol analog 673188 8.08245 7.89708 7.22394 7.63833 5.02336 6.90724 7.25259 7.70011 7.937175 7.08571 5.70049 7.45251 7.88136 6.90081 5.613815 7.513785 7.723665 8.06693 7.03164 6.7754 7.99207 8.16929 7.96902 8.21603 8.18677 5.833195 7.94643 8.25413 5.181715 7.741665 7.63272 7.799295 8.08709 8.066275 7.835865 7.9668 5.228395 6.27731 6.69486 5.41758 7.089885 7.0764 6.09594 6.38063 7.39885 6.96738 7.965565 7.65316 8.3288 8.22803 8.476255 5.00744 7.95112 7.40277 6.65979 8.27054 8.60206 8.60206 6.19446 8.030945 P90 Geldanamycin 330500 6.49676 6.695705 5.860705 6.39595 6.54099 6.95659 5.87997 6.65153 6.778645 5.9742 5.21252 5.68285 6.625675 6.47161 6.64979 5.621665 6.29445 6.32852 5.91886 5.91151 6.47945 6.79676 5.9849 6.51829 6.94688 5.20503 6.70348 6.653435 5.27189 5.81579 6.4838 6.478255 6.76101 6.93756 6.94156 6.82705 5.081445 6.42042 5.17247 5.1754 6.50001 5.88336 5.163635 5.39427 6.48094 5.31349 7.09431 5.94074 7.12295 6.655395 6.82455 5.14253 6.63768 6.52111 6.68312 5.839215 7.00076 6.72567 NA 6.680095 Uk 3-Hydropicolinaldehyde-thiosemicarbazone 95678 5.91558 5.58291 4.51154 5.948955 5.34665 6.260135 6.370795 6.19573 5.7595 5.511155 5.58851 5.54859 5.87571 5.915865 6.19273 5.57352 5.5604 5.65406 5.87705 6.18609 6.44154 5.62079 5.47385 5.62467 5.76855 5.75282 5.520695 5.739505 5.48891 6.07993 5.605305 5.34447 6.09937 5.65897 6.05118 6.38159 5.9262 5.96149 5.62905 6.0343 6.12691 6.485265 6.59117 5.35339 5.63184 5.46868 5.47619 5.54003 5.98641 6.021025 6.073475 6.08764 5.99326 6.31448 5.38168 4.46012 5.87514 5.772165 5.80064 5.46141 Uk 5-Hydroxypicolinaldehyde-thiosemicarbazone 107392 5.33372 5.16952 4.058305 5.17867 4.67257 5.05151 5.28299 5.42626 5.39486 4.388445 4.916045 5.078355 4.6335 5.302545 5.20492 4.85704 4.77045 5.21116 5.27544 4.559625 5.50939 4.54834 4.891415 5.14995 4.878575 5.0115 5.07914 5.54052 5.08184 5.46327 4.69971 4.59645 5.701475 5.20901 5.45574 5.81179 5.018405 5.24693 4.48402 4.97805 5.093665 5.3308 5.73748 3.947425 4.66087 4.629975 4.97821 4.52728 5.40113 5.02751 5.42617 5.37943 5.13498 5.489675 4.62028 3.518575 5.05652 5.032625 4.20976 5.298285 Uk Inosine-glycodialdehyde 118994 4.00344 3.49401 3.454 3.41959 3.41721 3.6028 3.275145 3.40504 3.831505 3.111425 3.43446 3.37124 3.17994 3.185665 3.58255 3.15291 3.21139 3.120685 3.363915 3.16562 3.16351 3.373355 3.407905 3.80382 3.85961 4.15802 3.47577 3.82694 3.47425 3.4298 3.77194 3.20656 4.10823 4.11276 3.97891 3.79125 3.36965 3.53049 3.15177 3.42879 3.54591 3.226365 3.29524 3.23599 3.42732 3.23693 3.48028 3.20905 4.478125 4.13468 4.121845 3.3559 3.40817 3.63009 3.93023 3.26803 3.62991 4.03794 3.36323 4.06288