The search term entered will be sent as a query to the
GeneCards server. The GeneCards search engine will process
the query and return GeneCards which have a matching field.
The returned gene names will be searched against the gene names
on the chip and highlight them. A comma-delimited list of id
numbers alone is provided, suitable for entry into local analysis
programs. For example, one can generate a dendogram of genes
related to the given pathway.
The gene synonym search terms are used to search the list of
gene synonyms. A radio button list of genes is shown on a new web page.
From there, two particular genes are chosen and the synonyms are shown on
a new web page. Any number of gene/disorder synonyms can be chosen
and new terms can be entered in a text entry box. The PubMed search is
conducted using a Boolean expression based on the synonyms chosen.
The drug synonym search term is used to search a list of
DTP/NCI drug synonyms.
A radio button list of drugs is shown on a new web page. From there,
one particular drug is chosen from the list and these synonyms are shown
on a new web page. Any number of drug synonyms can be chosen and new
terms can be entered in a text entry box. The PubMed search is conducted
using a Boolean expression based on the synonyms chosen.
At the top of the page, a link is provided to download all the abstracts.
A listing of relevant abstracts and sentences follows with a link to each
single complete abstract. Currently, relevance is determined by empirical
means, related to cancer. At the end of the page, a summary is shown
which shows the number of relevant abstracts and sentences extracted.
The default gene set is the list of Human OncoChip Genes
represented in the
NCI/DCS Human OncoGene set.
"MedMiner: an Internet Text-Mining Tool for Biomedical Information,
with Application to Gene Expression Profiling," L. Tanabe, U. Scherf,
L. H. Smith, J. K. Lee, L. Hunter and J. N. Weinstein,
BioTechniques 27(6), December 1999.
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