Gene DNA methylation values

This tool provides access to the DNA methylation data analyzed on the Illumina 450K methylation array.

The tool provides an Excel spreadsheet for each gene that includes:

  1. the estimated DNA methylation values in tabular and graphical forms (see below)
  2. the normalized data for those probes that fall within a gene of interest.

The data is queryable by gene or chromosomal location using Query Genomic Data under "DNA: Illumina 450K methylation" (http://discover.nci.nih.gov/cellminer/queryLoad.do).
The data may be obtained in toto at Download Data Sets under "DNA: Illumina 450K methylation" (http://discover.nci.nih.gov/cellminer/loadDownload.do).
A brief platform description is available in Data Set Metadata under "DNA: Illumina 450K methylation" (http://discover.nci.nih.gov/cellminer/datasets.do).
The gene methylation levels are measured as described in ...


Table 1: Gene methylation levels
Cell lines Methylation

BR:MCF7 0.114
BR:MDA_MB_231 -0.763
BR:HS578T -0.263
BR:BT_549 0.073
BR:T47D 0.151
CNS:SF_268 -0.282
CNS:SF_295 -1.216
CNS:SF_539 -1.208
CNS:SNB_19 -0.683
CNS:SNB_75 0.204
CNS:U251 -1.071
CO:COLO205 -0.522
CO:HCC_2998 0.415
CO:HCT_116 -0.162
CO:HCT_15 -0.643
CO:HT29 -1.675
CO:KM12 -0.565
CO:SW_620 0.098
LE:CCRF_CEM 0.028
LE:HL_60 0.385
LE:K_562 0.039
LE:MOLT_4 -1.073
LE:RPMI_8226 1.141
LE:SR 0.46
ME:LOXIMVI -0.212
ME:MALME_3M 0.082
ME:M14 0.129
ME:SK_MEL_2 0.62
ME:SK_MEL_28 1.57
ME:SK_MEL_5 0.24
ME:UACC_257 1.656
ME:UACC_62 0.327
ME:MDA_MB_435 0.1163
ME:MDA_N 0.013
LC:A549 -1.77
LC:EKVX -0.041
LC:HOP_62 -0.981
LC:HOP_92 0.211
LC:NCI_H226 -0.988
LC:NCI_H23 -0.108
LC:NCI_H322M 0.583
LC:NCI_H460 -0.33
LC:NCI_H522 0.174
OV:IGROV1 0.241
OV:OVCAR_3 0.494
OV:OVCAR_4 0.166
OV:OVCAR_5 1.174
OV:OVCAR_8 0.953
OV:SK_OV_3 -0.342
OV:NCI_ADR_RES -1.469
PR:PC_3 1.14
PR:DU_145 1.449
RE:786_0 0.652
RE:A498 0.461
RE:ACHN 0.38
RE:CAKI_1 1.279
RE:RXF_393 0.307
RE:SN12C -0.869
RE:TK_10 -0.006
RE:UO_31 -0.335