HTS384_NSC

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CellMiner Address: https://discover.nci.nih.gov/cellminer/
CellMiner Database Version: 2.14.1
Human Genome Version: HG-19
Date: 04-22-2025
Table 2: HTS384 NCI-60 Drug List

NSC	Drug name	FDA status	Mechanism of action	PubChem SID
740	Methotrexate	FDA approved	Df\|DHFR	126941
750	Busulfan	FDA approved	A7\|AlkAg	-
752	6-Thioguanine	FDA approved	Ds\|IMPDH2\|IMPDH	-
755	6-Mercaptopurine	FDA approved	Ds\|PPAT	-
762	Nitrogen mustard	FDA approved	A7\|AlkAg	-
1390	Allopurinol	FDA approved	AM\|XDH	-
3053	Actinomycin D	FDA approved	Db	-
3088	Chlorambucil	FDA approved	A7\|AlkAg	-
6396	Thiotepa	FDA approved	A7\|AlkAg	-
8806	Melphalan	FDA approved	A7\|AlkAg	-
9706	Triethylenemelamine	FDA approved	A7\|AlkAg	5799
13875	Altretamine	FDA approved	Db\|AlkAg	-
14229	Acrichine	FDA approved	Db\|AP	-
18509	Aminolevulinic acid	FDA approved	AM	-
19893	Fluorouracil	FDA approved	Ds\|Rs\|TYMS	-
24559	Mithramycin	FDA approved	Db\|Rs	-
25154	Pipobroman	FDA approved	A7\|AlkAg	-
26271	Cyclophosphamide	FDA approved	A7\|AlkAg	-
26980	Mitomycin	FDA approved	A2\|AlkAg	5746
27640	Floxuridine	FDA approved	Ds\|TYMS	-
32065	Hydroxyurea	FDA approved	AM\|Dr	-
34462	Uracil Mustard	FDA approved	A7\|AlkAg	6194
36405	Chelerythrine	Clinical trial	BCL2\|PK:PRKCA,STK	72311
38721	Mitotane	FDA approved	A7\|Ho\|AlkAg\|anti-Ho\|CYP11A1	-
45388	Dacarbazine	FDA approved	A7\|AlkAg	-
45923	Methoxsalen	FDA approved	Db	-
49842	Vinblastine	FDA approved	TUBB\|Tu-frag	-
62343	3-Bromopyruvate (acid)	Clinical trial	Mito\|HK2	-
63878	Cytarabine	FDA approved	Ds	-
66847	Thalidomide	FDA approved	Ang\|Immunomodulatory	-
67574	Vincristine	FDA approved	TUBB\|Tu-frag	249332
71423	Megestrol Acetate	FDA approved	Ho\|PGR	11683
75520	tfdu	FDA approved	TYMS	-
77213	Procarbazine	FDA approved	A7\|AlkAg	9703
79037	Lomustine	FDA approved	A6\|AlkAg	-
82151	Daunorubicin	FDA approved	TOP2	-
85998	Streptozocin	FDA approved	A7\|AlkAg	-
92859	Arsenic trioxide	FDA approved	Apo	261004
102816	Azacitidine	FDA approved	DNMT	-
105014	Cladribine	FDA approved	Ds\|ADA	-
109724	Ifosfamide	FDA approved	A7\|AlkAg	-
118218	Fludarabine	FDA approved	Ds\|AM\|Dr\|STAT1	-
119875	Cisplatin	FDA approved	A7\|AlkAg	-
122758	Isotretinoin	FDA approved	Ho\|RXR\|Differentiator	-
122819	Teniposide	FDA approved	TOP2	-
123127	Doxorubicin	FDA approved	TOP2	-
125066	Bleomycin	FDA approved	Db	-
125973	Paclitaxel	FDA approved	TUBB\|Tu-stab	-
127716	Decitabine	FDA approved	AM\|DNMT	-
130181	Tirapazamine	Clinical trial	DDI	-
138783	Bendamustine	FDA approved	A2\|A6\|AlkAg	77082
141540	Etoposide	FDA approved	TOP2	-
142784	Tempol	Clinical trial	RP\|FRS	-
169780	Dexrazoxane	FDA approved	TOP2\|NonCan:Cardioprotective	-
180973	Tamoxifen	FDA approved	Ho\|SERM	-
218321	Pentostatin	FDA approved	Ds\|AM\|ADA	-
221019	Wortmannin	Clinical trial	PK:PIK3	312145
226080	Rapamycin	FDA approved	PK:STK,MTOR	-
241240	Carboplatin	FDA approved	A7\|AlkAg	-
246131	Valrubicin	FDA approved	TOP2	-
256439	Idarubicin	FDA approved	TOP2	-
256942	Epirubicin	FDA approved	TOP2	-
266046	Oxaliplatin	FDA approved	A7\|AlkAg	-
279836	Mitoxantrone	FDA approved	TOP2	4212
296961	Amifostine	FDA approved	RP	-
312887	Fludarabine	FDA approved	Ds\|AM\|Dr\|STAT1	-
330507	Tanespimycin	Clinical trial	HSP90	-
350625	tic10	Clinical trial	-	-
362856	Temozolomide	FDA approved	A7\|AlkAg	-
369100	Imiquimod	FDA approved	AM\|TLR7\|ImmuneResMod	-
409962	Carmustine	FDA approved	A7\|AlkAg	-
606869	Clofarabine	FDA approved	Ds	354624
608210	Vinorelbine	FDA approved	TUBB\|Tu-frag	25136944
609699	Topotecan	FDA approved	TOP1	-
613327	Gemcitabine	FDA approved	Ds	60750
616348	Irinotecan	FDA approved	TOP1	-
628503	Docetaxel	FDA approved	TUBB\|Tu-stab	148124
637037	O-6-Benzylguanine	Clinical trial	DDR\|MGMT	4578
639186	Raltitrexed	FDA approved	Ds\|DHFR\|TYMS	135400182
639966	Perifosine	Clinical trial	PK:STK,AKT,AKT1,AKT2,AKT3	148177
649890	Alvocidib	Clinical trial	CCNT1\|PK:STK,CDK,CDK1,CDK2,CDK4,CDK6,CDK7,CDK8,CDK9	-
673596	7-Ethyl-10-hydroxycamptothecin	FDA approved	TOP1	104842
678515	FAU	Clinical trial	Db	-
679828	PD-98059	Clinical trial	PK:STK,MAP2K,MAP2K1,MAP2K2	-
683863	Irofulven	FDA approved	Apo\|AlkAg\|RDI	148189
683864	Temsirolimus	FDA approved	PK:STK,MTOR	-
686288	Aminoflavone	Clinical trial	Db\|DDI	389710
698215	XK-469	Clinical trial	TOP2	3246729
701554	Seliciclib	Clinical trial	PK:STK,CDK,CDK2,CDK7,CDK9	160355
701852	Vorinostat	FDA approved	HDAC	-
702294	Estramustine	FDA approved	A7\|TUBB\|AlkAg	54611422
703081	SL-0101	Clinical trial	RPS6	14825856
707545	Alvespimycin	Clinical trial	HSP90	-
710464	AFP464	Clinical trial	Db\|DDI	399587
712807	Capecitabine	FDA approved	Ds\|TYMS	400633
713563	Exemestane	FDA approved	Ho\|CYP19A1	60198
715055	Gefitinib	FDA approved	PK:YK,EGFR	-
718781	Erlotinib	FDA approved	PK:YK,EGFR	-
719276	Fulvestrant	FDA approved	AM\|Ho\|ESR\|SERM	104741
719344	Anastrozole	FDA approved	Ho\|CYP19A1	-
719345	Letrozole	FDA approved	Ho\|CYP19A1	-
719627	Celecoxib	FDA approved	AM\|PTGS2\|COX2\|NonCan:NSAID	-
721517	Zoledronate	FDA approved	AM\|NonCan:Anti-bone resorp	68740
721782	D-1MT	Clinical trial	AM\|INDO\|IDO1\|PK:ROS1	405012
722134	Sonolisib	Clinical trial	PK:PIK3	-
727859	(R)-(-)-Gossypol acetic acid	Clinical trial	Apo\|BCL2	24203396
732517	Dasatinib	FDA approved	BCR-ABL\|PK:YK,PDGFR,KIT	-
733504	Everolimus	FDA approved	PK:STK,MTOR	-
737754	Pazopanib	FDA approved	PK:YK,PDGFR,FGFR,KIT,VEGFR	11525740
741078	Selumetinib	FDA approved	PK:STK,YK,MAP2K,MAP2K1,MAP2K2	10127622
741899	BML-277	Clinical trial	PK:CHEK,CHEK2	9969021
743414	Imatinib	FDA approved	BCR-ABL\|PK:YK	-
745750	Lapatinib	FDA approved	PK:STK,YK,MET,EGFR,ERBB2,KIT,RAF,VEGFR	208908
747599	Nilotinib	FDA approved	BCR-ABL\|PK:YK	644241
747971	Sorafenib	FDA approved	PK:YK,PDGFR,BRAF,KIT,VEGFR,Multikinase	216239
747972	Lenalidomide	FDA approved	FT\|Immunomodulatory	216326
747973	Ixabepilone	FDA approved	TUBB\|Tu-stab	6445540
747974	Raloxifene	FDA approved	Ho\|SERM	5035
749226	Abiraterone	FDA approved	Ho\|CYP17A1	132971
750690	Sunitinib	FDA approved	PK:YK,PDGFR,KIT,VEGFR,Multikinase	5329102
750691	Afatinib	FDA approved	PK:YK,EGFR	10184653
751249	Dactolisib	Clinical trial	PK:STK,PIK3,MTOR	11977753
751297	Y-27632	Clinical trial	RHO	-
752493	Iniparib	Clinical trial	PARP\|PARP1\|PARP2	-
752840	Veliparib	Clinical trial	PARP\|PARP1\|PARP2	-
753686	Olaparib	FDA approved	PARP\|PARP1	-
754143	Depsipeptide	FDA approved	HDAC	5352062
754230	Pralatrexate	FDA approved	Df\|CTNNB1\|DHFR	148121
754344	Rigosertib	Clinical trial	RAS\|Tu-stab\|PK:STK,PLK1	-
754345	JNJ-28312141	Clinical trial	PK:YK,CSF1R	-
754346	AMG-458	Clinical trial	PK:YK,MET	-
754348	PF-03084014 diastereomer 1	Clinical trial	PSM\|APH1\|Gamma secretase	-
754349	Amuvatinib	Clinical trial	RAD51\|PK:YK,PDGFR,KIT,FLT3,Multikinase	-
754350	CB-64D	Clinical trial	Sig2Rec	-
754352	Adavosertib	Clinical trial	PK:STK,YK,WEE1	-
754353	Buparlisib	Clinical trial	PK:PIK3	-
754354	GSK-461364	Clinical trial	PK:STK,PLK1	-
754355	Niraparib	FDA approved	PARP\|PARP1\|PARP2	-
754356	PF-562271	Clinical trial	PK:YK,FAK	-
754357	RAF-265	Clinical trial	GTPase\|PK:BRAF	-
754358	TDP-665759	Clinical trial	Apo\|MDM2	-
754359	AEG-40730	Clinical trial	Apo\|IAP	-
754360	MI-219	Clinical trial	Apo\|MDM2	-
754361	Astex FGF inhibitor	Clinical trial	PK:YK,FGFR	-
754362	SB-590885	Clinical trial	GTPase\|PK:YK,BRAF	-
754364	Targegen B-Raf/PDGFR inhibitor Cpd 6	Clinical trial	GTPase\|PK:YK,PDGFR,BRAF	-
754365	XR-11576	Clinical trial	TOP2\|TOP1	-
754366	XR-5944	Clinical trial	TOP2\|TOP1	-
754367	XR-5000	Clinical trial	TOP2\|TOP1	-
755384	Pemetrexed	FDA approved	Df\|AM\|GARTF\|DHFR\|TYMS	-
755385	Pictilisib	Clinical trial	PK:PIK3	-
755386	Ispinesib	Clinical trial	TUBB\|CC\|CDH16\|KIF11\|Kinesin\|PK:YK	-
755387	Sepantronium bromide	Clinical trial	Apo\|BIRC5	-
755389	Bosutinib	FDA approved	STAT\|BCR-ABL\|STAT5A/B\|PK:YK,LYN,SRC,HCK	-
755400	Masitinib	FDA approved	PK:YK,PDGFR,FGFR,KIT,FGFR3	-
755401	Golotimod	FDA approved	STAT\|STAT3	-
755605	Enzalutamide	FDA approved	Ho\|AR	-
755606	Cediranib	FDA approved	PK:YK,VEGF,VEGFR,KDR	-
755761	XAV-939	Clinical trial	Wnt\|PK:YK,TNKS	-
755762	Luminespib	Clinical trial	HSP90	-
755763	Pimasertib	Clinical trial	PK:STK,YK,MAP2K,MAP2K1,MAP2K2	-
755765	GW-5074	Clinical trial	GTPase\|PK:RAF,RAF1	-
755766	H-89	Clinical trial	Protein kinase A\|PK:STK,AKT1	-
755769	LY-294002	Clinical trial	PK:PIK3	-
755770	PD-0325901	Clinical trial	PK:STK,MAP2K,MAP2K1	-
755771	Salirasib	Clinical trial	GTPase\|RAS\|PK:YK,MTOR	-
755772	SB-203580	Clinical trial	PK:STK,MAPK14,PDK1	-
755773	1,9-Pyrazoleanthrone	Clinical trial	PK:STK,MAPK14,MAPK8	-
755774	Staurosporine	Clinical trial	PK:PRKCA,SRC,Multikinase	-
755775	Foretinib	Clinical trial	PK:YK,MET,AXL,VEGFR,KDR,RON,Multikinase	-
755892	Hydrastinine HCl	Clinical trial	NonCan:Antihemorrhagic	-
755926	PF-03084014 diastereomer 1	Clinical trial	PSM\|APH1\|Gamma secretase	-
755927	WZ-4002	Clinical trial	PK:YK,EGFR	-
755980	Lenvatinib	FDA approved	PK:YK,PDGFR,FGFR,VEGFR,KDR,RET	-
755981	WP-1034	Clinical trial	STAT\|PK:YK,JAK	-
755982	Semagacestat	Clinical trial	PSM\|APH1\|Gamma secretase	-
755983	BI-2536	Clinical trial	PK:STK,PLK1	-
755984	Pralatrexate	FDA approved	Df\|CTNNB1\|DHFR	-
755985	Nelarabine	FDA approved	Ds	3011155
755986	Vismodegib	FDA approved	SMO\|PK:YK	-
756641	ICG-001	Clinical trial	Apo\|Wnt\|CTNNB1	-
756642	Entinostat	Clinical trial	HDAC	-
756643	KX-01	FDA approved	PK:YK,SRC	-
756644	Rucaparib	FDA approved	PARP\|PARP1	-
756645	Crizotinib	FDA approved	PK:YK,MET,ALK	54613769
756646	IWR-1	Clinical trial	Wnt\|CTNNB1	-
756647	Quizartinib	FDA approved	PK:YK,PDGFR,FLT,KIT,FLT3	-
756648	AZD-1480	Clinical trial	PK:YK,JAK,JAK1,JAK2	-
756649	SB-431542	Clinical trial	TGFB1\|PK:STK,GSK3B	-
756650	RO-4929097	Clinical trial	PSM\|APH1\|Gamma secretase	-
756652	Linsitinib	Clinical trial	PK:YK,IGF1R	-
756653	SB-239063	Clinical trial	PK:STK,MAPK14	-
756654	ZM-336372	Clinical trial	GTPase\|PK:BRAF,RAF,RAF1	-
756655	Bortezomib	FDA approved	PSM	-
756656	MK-2206	FDA approved	PK:STK,AKT,AKT1,AKT2,AKT3	-
756657	OSU-03012	Clinical trial	PK:STK,PDK1	-
756658	OSU-03013	Clinical trial	PK:STK,PDK1	-
756659	Intedanib	FDA approved	PK:YK,PDGFR,FGFR,VEGFR,FLT3	-
756660	Quercetin	Clinical trial	TOP2\|AO\|NonCan:COMT	-
756662	sr 13654	Clinical trial	BIRC5\|PK:YK	-
756663	Obatoclax	Clinical trial	Apo\|BCL2	-
756874	NU-6027	Clinical trial	PK:STK,ATR	-
756875	(+/-)-Nutlin-3	Clinical trial	Apo\|MDM2	-
756876	(-)-Nutlin-3	Clinical trial	Apo\|MDM2	-
756879	Lificguat	Clinical trial	HYP\|HIF1\|EPAS1	-
757148	AZD-7762	Clinical trial	PK:STK,CHEK,CHEK1,CHEK2	-
757149	Volasertib	Clinical trial	PK:STK,PLK1	-
757333	SGI-1776	Clinical trial	PK:STK,PIM1	-
757334	Cpd-401	Clinical trial	STAT\|STAT3	-
757437	Salinomycin	FDA approved	Apo\|Ab\|CD133	-
757438	PLX-4720	Clinical trial	GTPase\|PK:BRAF	-
757439	Neratinib	FDA approved	PK:YK,EGFR,ERBB2	-
757440	Deforolimius	Clinical trial	PK:STK,MTOR	-
757441	Axitinib	FDA approved	PK:YK,PDGFR,VEGFR	6450551
757444	Barasertib	Clinical trial	PK:STK,AURK	-
758005	Sapitinib	Clinical trial	PK:YK,EGFR,ERBB2	-
758006	BLZ-945	Clinical trial	PK:CSF1R	-
758007	Tivozanib	FDA approved	PK:YK,MET,PDGFR,FGFR,KIT,VEGFR,FLT3,KDR	-
758242	Tivantinib	Clinical trial	PK:YK,MET	-
758243	BMS-754807	Clinical trial	PK:YK,IGF1R	-
758244	tepotinib	FDA approved	PK:YK,MET	-
758245	ENMD-2076	Clinical trial	PK:STK,AURK,KDR	-
758246	Trametinib	FDA approved	PK:STK,MAP2K,MAP2K1,MAP2K2	-
758247	Palbociclib	FDA approved	PK:STK,CDK,CDK4,CDK6	-
758248	RO-5126766	Clinical trial	GTPase\|PK:STK,YK,BRAF,MAP2K,RAF,MAP2K1,MAP2K2	-
758249	Pracinostat	Clinical trial	HDAC	-
758250	SNS-314	Clinical trial	PK:STK,AURK	-
758251	Amonafide	Clinical trial	TOP2	-
758252	Carfilzomib	FDA approved	PSM	-
758253	Homoharringtonine	FDA approved	Apo\|Ang\|Pi	-
758254	Ixazomib citrate	FDA approved	PSM	-
758256	PKI-587	Clinical trial	PK:STK,PIK3,MTOR	-
758257	LY-2606368	Clinical trial	PK:STK,CHEK,CHEK1	-
758484	Ezatiostat	Clinical trial	GSTP1\|PK:STK,ROS1	-
758485	BX-912	Clinical trial	PK:STK,PDK1	-
758486	HPI-1	Clinical trial	SMO\|Hg-Smo	-
758487	Ponatinib	FDA approved	BCR-ABL\|PK:YK	-
758488	Lexibulin	Clinical trial	TUBB\|Tu-frag\|Tu-stab	-
758489	Indibulin	Clinical trial	TUBB\|Tu-frag\|PK:PTK	-
758490	Picoplatin	Clinical trial	A7\|CC\|AlkAg\|IDNARep	-
758591	SGX-523	Clinical trial	PK:YK,MET	-
758773	Varbulin	Clinical trial	TUBB\|Tu-frag	-
758774	Belinostat	FDA approved	HDAC	-
758871	AZD-8055	Clinical trial	PK:STK,MTOR	-
758872	Saracatinib	Clinical trial	PK:YK,FYN,LYN,FGFR,SRC,BLK,LCK,YES1	-
758873	ABT-737	Clinical trial	Apo\|BCL2	-
759094	ENMD-2076 Precursor	Clinical trial	PK:STK,AURK	-
759095	JNJ-38877605	Clinical trial	PK:YK,MET	-
759096	Triapine	Clinical trial	Dr\|CC	-
759224	Idelalisib	FDA approved	PK:PIK3	-
759498	CYC-116	Clinical trial	PK:STK,AURK	-
759657	Quisinostat	Clinical trial	HDAC	-
759658	6-(4-pyrimidinyl)-1H-indazole derivative	Clinical trial	PK:STK,PDK1	-
759659	Navitoclax	Clinical trial	Apo\|BCL2	-
759660	OSI-027	Clinical trial	PK:STK,MTOR	-
759661	Dovitinib	Clinical trial	PK:YK,MET,PDGFR,EGFR,FGFR,KIT,VEGFR,FGFR1,FGFR3,FLT3	-
759675	KW-2449	Clinical trial	BCR-ABL\|PK:STK,AURK,FLT,FLT3	-
759676	PI-103	Clinical trial	PK:PIK3,MTOR	-
759677	Alisertib	Clinical trial	PK:STK,AURK	-
759905	4SC-202	Clinical trial	HDAC	-
760143	Mocetinostat	Clinical trial	HDAC	-
760144	AT-9283	Clinical trial	PK:STK,AURK	-
760444	Tipifarnib	Clinical trial	FT\|PK:YK	-
760536	PF-04691502	Clinical trial	PK:PIK3	-
760764	Voreloxin	FDA approved	TOP2	-
760765	BMS-690514	Clinical trial	PK:YK,EGFR,ERBB2,VEGFR	-
760766	Vandetanib	FDA approved	PK:STK,YK,PDGFR,EGFR,VEGFR,RET	-
760841	Tandutinib	Clinical trial	PK:YK,PDGFR,FLT,KIT,FLT3	-
760842	BIM-46187	Clinical trial	Apo\|GTPase\|CASP	-
760843	Motesanib	Clinical trial	PK:YK,PDGFR,KIT,VEGFR,KDR,RET	-
761068	Cabozantinib	FDA approved	PK:YK,MET,AXL,KIT,VEGFR,FLT3,RET	-
761069	AMG-900	Clinical trial	PK:STK,AURK	-
761070	VE-821	Clinical trial	PK:STK,ATR	-
761188	Rabusertib	Clinical trial	PK:STK,CHEK,CHEK1	-
761189	Teglarinad	Clinical trial	Apo\|NAMPT	-
761190	Panobinostat	FDA approved	HDAC	-
761192	Pevonedistat	Clinical trial	NFkB\|NEDD8	-
761193	Silmitasertib	Clinical trial	CK2\|PK:STK	-
761194	CUDC-305	Clinical trial	HSP90	-
761215	TAK-733	Clinical trial	PK:STK,MAP2K,MAP2K1,MAP2K2	-
761216	Galunisertib	Clinical trial	TGFB1\|PK:GSK3B	-
761217	Avagacestat	Clinical trial	PSM\|APH1\|Gamma secretase	-
761266	Motexafin	Clinical trial	Dr\|TXNRD\|PK:ROS1	-
761385	Sonidegib	FDA approved	SMO\|Hg-Smo	-
761387	CCT-128930	Clinical trial	PK:STK,AKT,AKT1,AKT2,AKT3	-
761388	Plerixafor	FDA approved	CXCR4	-
761431	Vemurafenib	FDA approved	PK:YK,BRAF	42611257
761432	Cabazitaxel	FDA approved	TUBB\|Tu-stab	9854073
761690	CP-91149	Clinical trial	PYGL	-
761691	SCH-1473759	Clinical trial	PK:STK,AURK	-
761692	MK-8033	Clinical trial	PK:YK,MET	-
761693	Vertex ATR inhibitor Cpd 45	Clinical trial	PK:STK,ATR	-
761759	TAK-960 analog	Clinical trial	PK:STK,PLK1	-
761760	BMS-536924	Clinical trial	PK:YK,IGF1R	-
761879	ITRI-260	Clinical trial	PK:YK,FLT,FLT3	-
761910	Ibrutinib	FDA approved	PK:YK,BTK	-
761931	KHK-Indazole	Clinical trial	PK:YK,IGF1R	-
762151	TAK-901	Clinical trial	PK:STK,AURK	-
762152	ONX-0914	Clinical trial	PSM	-
762153	ST-3595	Clinical trial	HDAC	-
762154	Des-fluoro-TAK-960	Clinical trial	PK:STK,PLK1	-
762381	CGI Diphenylurea PK inhibitor	Clinical trial	PK:YK,EPHA4,PDGFR,VEGFR	-
762382	CH-5132799	Clinical trial	PK:PIK3	-
762418	TAK Plk inhibitor	Clinical trial	PK:STK,PLK1	-
762419	CT-32228	Clinical trial	AGPAT2\|PK:YK,VEGFR	-
762521	RO-4987655	Clinical trial	PK:STK,MAP2K	-
762598	BAL-27862	Clinical trial	TUBB\|Tu-frag	-
762672	BMS-299897	Clinical trial	PSM\|APH1\|Gamma secretase	-
762673	SB-1317	Clinical trial	PK:STK,CDK,ERK,FLT,JAK,FLT3	-
762829	MK-0752	Clinical trial	PSM\|APH1\|Gamma secretase	-
763094	JZL-184	Clinical trial	MGLL	-
763371	Ruxolitinib	FDA approved	PK:YK,JAK,JAK1,JAK2	-
763443	(+)-Nutlin-3	Clinical trial	Apo\|MDM2	-
763444	PF-477736	Clinical trial	PK:STK,CHEK,CHEK1	-
763525	Pluripotin	Clinical trial	GTPase\|RAS\|RASA1\|PK:STK,MAP3K	-
763526	Crenolanib	Clinical trial	PK:YK,PDGFR,KIT,VEGFR,TEK,FLT3	-
763527	JZL-195	Clinical trial	MGLL	-
763564	EMD-534085	Clinical trial	CDH16\|KIF11\|Kinesin\|PK:YK	-
763579	AT-13387	Clinical trial	HSP90	-
763758	SEN-450	Clinical trial	SMO	-
763929	Orantinib	Clinical trial	PK:YK,PDGFR,FGFR,VEGFR,KDR	-
763931	PF-04217903	Clinical trial	PK:MET	-
763932	Regorafenib	FDA approved	GTPase\|PK:STK,YK,PDGFR,FGFR,KIT,MAP2K,RAF,VEGFR,KDR,RET,Multikinase	-
764036	Dinaciclib	Clinical trial	PK:STK,CDK,CDK1,CDK2,CDK5,CDK9	-
764037	BP-1-102	Clinical trial	STAT\|IL6\|STAT3	-
764039	AZD-5363	Clinical trial	PK:STK,AKT,AKT1,AKT2,AKT3	-
764040	Alectinib	FDA approved	PK:YK,ALK	-
764041	TAE-684	Clinical trial	PK:YK,ALK	-
764042	ARRY-162	FDA approved	PK:STK,MAP2K,MAP2K1,MAP2K2	-
764043	(+)-JQ1	Clinical trial	BRD	-
764090	BMS-777607	Clinical trial	PK:MET,RON	-
764091	Apitolisib	Clinical trial	PK:PIK3,MTOR	-
764092	GSK-2126458	Clinical trial	PK:PIK3	-
764134	Dabrafenib	FDA approved	PK:BRAF	-
764135	BMS-599626	Clinical trial	PK:YK,EGFR,ERBB2	-
764136	Abexinostat	Clinical trial	HDAC	-
764237	Linifanib	Clinical trial	PK:YK,CSF1R,PDGFR,VEGFR,FLT3,KDR	-
764238	6-Bromoindirubin-3'-Acetoxime	Clinical trial	PK:GSK3A	-
764239	AZD-4547	Clinical trial	PK:YK,FGFR,FGFR1,FGFR2,FGFR3	-
764276	t-dcyd	Clinical trial	-	-
764334	delanzomib	Clinical trial	PSM	-
764481	Brivanib	Clinical trial	PK:YK,FGFR,VEGFR,FGFR1,FGFR2,FGFR3,KDR	-
764487	NVP-BGJ398	FDA approved	PK:FGFR,FGFR1,FGFR2,FGFR3,FGFR4	-
764488	Orteronel	Clinical trial	CYP17A1	-
764515	PP-242	Clinical trial	PK:MTOR	-
764516	ZSTK-474	Clinical trial	PK:PIK3	-
764517	UNC-0638	Clinical trial	EHMT2\|EHMT1/2	-
764579	Inolitazone hydrochloride	Clinical trial	PPARG	-
764580	MK-2461	Clinical trial	PK:MET,FGFR	-
764581	ARRY-380	FDA approved	PK:ERBB2	-
764582	10058-F4	Clinical trial	MYC	-
764608	BAL-101553	Clinical trial	Tu-frag	-
764609	10074-G5	Clinical trial	MYC	-
764658	INK-128	Clinical trial	PK:MTOR	-
764659	SCH-900776	Clinical trial	PK:STK,CHEK,CHEK1	-
764755	Cerulenin	Clinical trial	FAS\|FASN\|HMGCS1/2	-
764756	C-75	Clinical trial	FAS\|FASN	-
764757	SM-406	Clinical trial	IAP	-
764764	ONX-0801	Clinical trial	TYMS	-
764765	ARQ-680	Clinical trial	PK:BRAF	-
764820	Gandotinib	Clinical trial	PK:JAK,JAK2,JAK3	-
764821	Alectinib	FDA approved	PK:YK,ALK	-
764823	Varlitinib	Clinical trial	PK:YK,EGFR,ERBB2	-
765395	MPC-3100	Clinical trial	HSP90	-
765396	BMN-673	FDA approved	PARP1\|PARP2	-
765435	Ganetespib	Clinical trial	HSP90	-
765436	YK-4-279	Clinical trial	ERG\|ETV	-
765632	LY-2109761	Clinical trial	TGFB1\|PK:GSK3B	-
765672	S-49076	Clinical trial	PK:MET,AXL,FGFR,MERTK	-
765694	Bosutinib	FDA approved	STAT\|BCR-ABL\|STAT5A/B\|PK:YK,LYN,SRC,HCK	-
765695	PD 184352	Clinical trial	PK:MAP2K	-
765775	Gemcitabine elaidate	Clinical trial	Ds	-
765776	AZD-3514	Clinical trial	AR	-
765865	ASP-3026	Clinical trial	PK:ALK	-
765866	Refametinib	Clinical trial	PK:MAP2K,MAP2K1,MAP2K2	-
765888	Dacomitinib	FDA approved	PK:EGFR,ERBB2	-
765889	ABT-348	Clinical trial	PK:AURK,VEGFR	-
765898	GDC-0152	Clinical trial	IAP	-
765949	AEE-788	Clinical trial	PK:EGFR,ERBB2,VEGF,VEGFR	-
765974	BYL-719	FDA approved	PK:PIK3	-
766254	Oprozomib	Clinical trial	PSM	-
766255	CT-GSK183	Clinical trial	PK:IGF1R,ALK	-
766270	ABT-199	FDA approved	BCL2	-
766271	PHA-665752	Clinical trial	PK:MET	-
766288	AMG-208	Clinical trial	PK:MET	-
766811	Odanacatib	Clinical trial	CTSB	-
766819	Sotrastaurin	Clinical trial	PK:PRKCA	-
766820	LY-2228820	Clinical trial	PK:MAPK14	-
766821	BMS-911543	Clinical trial	PK:JAK,JAK1,JAK2,JAK3	-
766824	CEP-14083	Clinical trial	PK:ALK	-
766887	OSI-930	Clinical trial	PK:PDGFR,KIT,VEGFR,Multikinase	-
766888	BBOA	Clinical trial	AEMD	-
766906	MLN-2480	Clinical trial	PK:BRAF,RAF,RAF1	-
766907	Ixazomib	FDA approved	PSM	-
766908	PD 173074	Clinical trial	PK:PDGFR,FGFR,SRC,VEGFR,FGFR1,FGFR3	-
766991	GSK-690693	Clinical trial	PK:AKT,AKT1,AKT2,AKT3	-
766992	BAY 61-3606	Clinical trial	PK:SYK	-
767006	AEW-541	Clinical trial	PK:YK,IGF1R	-
767048	BMS-387032	Clinical trial	PK:CDK,CDK2,CDK7,CDK9	-
767123	Saridegib	Clinical trial	SMO	-
767124	Enzastaurin	Clinical trial	PK:PRKCA,STK,PIK3,AKT	-
767125	BMN-673	FDA approved	PARP1\|PARP2	-
767126	LEQ-506	Clinical trial	SMO	-
767128	Birinapant	Clinical trial	IAP	-
767470	MLN-0905	Clinical trial	PK:PLK1	-
767533	BMN-673 enantiomer	Clinical trial	PARP1	-
767598	Momelotinib	Clinical trial	PK:JAK,JAK1,JAK2,JAK3	-
767599	I-BET-151	Clinical trial	BRD	-
767600	Fedratinib	FDA approved	PK:FLT,JAK,FLT3,JAK2,RET	-
767601	VX-944	Clinical trial	IMPDH2\|IMPDH1\|IMPDH	-
767745	Pelitrexol	Clinical trial	GARTF	-
767746	ADW-742	Clinical trial	PK:IGF1R,KIT	-
767896	LY-2940680	Clinical trial	SMO	-
767897	BPR1J-097	Clinical trial	PK:FLT,FLT3	-
767898	ipatasertib	Clinical trial	PK:AKT,AKT1,AKT2,AKT3	-
767951	GSK-1904529A	Clinical trial	PK:IGF1R	-
767952	rocilinostat	Clinical trial	HDAC	-
767953	R-1530	Clinical trial	PK:PDGFR,CDK,FGFR,VEGFR,KDR,Multikinase	-
767954	EMD-1204831	Clinical trial	PK:MET	-
768011	XL-541	Clinical trial	GEMIN2	-
768068	Cobimetinib (isomer 1)	FDA approved	PK:MAP2K,MAP2K1	-
768069	Cobimetinib (isomer 1)	FDA approved	PK:MAP2K,MAP2K1	-
768070	enantiomer of PF-4176340	Clinical trial	PK:AKT	-
768071	enantiomer of PF-4176340	Clinical trial	PK:AKT	-
768072	TAK-960	Clinical trial	PK:PLK1	-
768073	LY-2835219	FDA approved	PK:PIM1,CDK,CDK4,CDK6	-
768112	SAR-402674	Clinical trial	TOP1	-
768508	GSK-2636771	Clinical trial	PK:PIK3,MTOR	-
768509	SNX-5422	Clinical trial	HSP90	-
768536	BAM7	Clinical trial	BCL2	-
768539	IDH1-Comp 301	Clinical trial	IDH1	-
768593	CEP-9722	Clinical trial	PARP1	-
771532	GDC-0349	Clinical trial	PK:MTOR,PIM3	-
771644	ARQ-621	Clinical trial	CDH16\|KIF11	-
771649	ARN-509	FDA approved	AR	-
771650	AT-13148	Clinical trial	PK:AKT,AKT1,AKT2,AKT3	-
771651	VX-322	Clinical trial	PK:FLT,KIT,FLT3	-
771652	SAR-125844	Clinical trial	PK:MET	-
771750	LY-2874455	Clinical trial	PK:FGFR,VEGFR,FGFR1,FGFR2,FGFR3,FGFR4	-
771751	CUDC-907	Clinical trial	HDAC\|PK:PIK3	-
771858	TAK-441	Clinical trial	SMO	-
772196	Lestaurtinib	Clinical trial	PK:YK,FLT,NTRK,FLT3,JAK2	-
772197	LY-2801653	Clinical trial	PK:MET,AXL,FLT3,MERTK,MST1R,Multikinase	-
772198	LY-2090314	Clinical trial	PK:GSK3A,GSK3B	-
772254	ARRY-520 Isomer A	Clinical trial	CDH16	-
772255	ARRY-520 Isomer A	Clinical trial	CDH16	-
772290	Pelitrexol isomer A	Clinical trial	GARTF	-
772291	Pelitrexol isomer B	Clinical trial	GARTF	-
772351	XL-888	Clinical trial	HSP90	-
772469	IPI-145	FDA approved	PK:PIK3	-
772498	r406	Clinical trial	PK:SYK	-
772499	Vatalanib	Clinical trial	CYP19A1\|PK:YK,PDGFR,KIT,VEGFR,KDR	-
772563	ARRY-704	Clinical trial	PK:MAP2K,MAP2K1,MAP2K2	-
772564	IDH-C227	Clinical trial	IDH1	-
772595	KPT-185	Clinical trial	XPO1	-
772868	LCL-161	Clinical trial	IAP	-
772885	PF-4942847	Clinical trial	HSP90	-
772886	Apatinib	Clinical trial	PK:VEGFR	-
772887	XL-019	Clinical trial	PK:JAK,JAK2	-
772920	ONX-0805	Clinical trial	PK:JAK,JAK2	-
772991	PKM2 (9)	Clinical trial	PKM	-
772992	Fostamatinib	Clinical trial	Ds\|Rs\|PK:YK,SYK	-
773094	R-547	Clinical trial	PK:CDK,CDK1,CDK2,CDK4	-
773095	BGT-226	Clinical trial	PK:PIK3	-
773096	IDH-C35	Clinical trial	IDH1	-
773174	LDHA Inhibitor-33	Clinical trial	LDHA	-
773230	AZD-2461	Clinical trial	PARP1\|PARP2	-
773260	KPT-251	Clinical trial	XPO1	-
773261	GSK-921	Clinical trial	CDH16\|KIF11	-
773262	VX-689	Clinical trial	PK:AURK	-
773264	R-306465	Clinical trial	HDAC	-
773265	B-7100	Clinical trial	HSP90	-
773394	AT-7519	Clinical trial	RNA polymerase I\|PK:CDK,CDK1,CDK2,CDK4,CDK6	-
774651	Cilengitide	Clinical trial	Ang\|ITG	-
774769	NMS-E628	FDA approved	PK:ROS1,ALK	-
774829	I-BET-762	Clinical trial	BRD	-
774830	Milciclib	Clinical trial	PK:CDK,CDK1,CDK2,CDK4,CDK5,Multikinase	-
774831	Rebastinib	Clinical trial	BCR-ABL\|PK:LYN,FGFR,SRC,VEGFR,TEK	-
774901	AZD-2858	Clinical trial	Wnt\|PK:GSK3A	-
774911	BAY-1000394	Clinical trial	PK:CDK	-
775018	LDHA Cmp 35	Clinical trial	LDHA	-
775306	P-529	Clinical trial	PK:PIK3,AKT,FGFR,MTOR,VEGFR	-
775351	Pomalidomide	FDA approved	Immunomodulatory	-
775636	SCH-772984	Clinical trial	PK:ERK,MAP3K,MAPK1	-
775637	AMD-070	Clinical trial	CXCR4	-
775665	VX-702	Clinical trial	PK:MAPK14	-
775727	Torin2	Clinical trial	PK:MTOR	-
775771	BMS-863233	Clinical trial	PK:CDC7,CDK7,CDK9	-
775772	PF-04449913	FDA approved	SMO	-
776017	Telatinib	Clinical trial	PK:PDGFR,KIT,VEGFR,KDR	-
776043	CEP-32496	Clinical trial	PK:BRAF	-
776066	AZD-1208	Clinical trial	PK:PIM1,PIM2,PIM3	-
776422	LDK-378	FDA approved	PK:ALK	-
776762	EXEL-7647	Clinical trial	PK:EGFR,ERBB2,SRC,VEGFR	-
776786	P505-15	Clinical trial	PK:SYK	-
776787	AZD-3463	Clinical trial	PK:IGF1R,ALK	-
776790	MK-0429	Clinical trial	ITG	-
776821	CCT-241533	Clinical trial	PK:CHEK,CHEK2	-
776996	PI-103	Clinical trial	PK:PIK3,MTOR	-
777109	E-7438	FDA approved	EZH2	-
777194	Daporinad	Clinical trial	NAMPT\|PK:YK	-
777425	GDC-0032	Clinical trial	PK:PIK3	-
777445	GSK-1070916	Clinical trial	PK:AURK	-
777446	Talmapimod	Clinical trial	PK:MAPK14	-
777447	VTX-2337	Clinical trial	TLR8	-
777448	PFI-1	Clinical trial	BRD	-
777571	BIX-01294	Clinical trial	EHMT2\|EHMT1/2	-
777572	AZD-8186	Clinical trial	PI3KB\|PK:PIK3	-
777573	E-7820	Clinical trial	Ang\|ITG	-
777586	5-aza-T-dCyd	Clinical trial	-	-
777638	AZD-6738	Clinical trial	PK:ATR	-
777639	LGK-974	Clinical trial	Wnt\|PORCN	-
777671	BRD-4770	Clinical trial	EHMT2\|EHMT1/2	-
777718	VE-822	Clinical trial	PK:ATR	-
777877	PF-4989216	Clinical trial	PK:PIK3	-
777878	TABRECTA	FDA approved	PK:MET	-
777879	AM-5992	Clinical trial	PK:CDK,FLT,FLT3	-
778304	Encorafenib	FDA approved	PK:BRAF	-
778305	Afuresertib	Clinical trial	PK:AKT,AKT1,AKT2,AKT3	-
778364	Defactinib	Clinical trial	PK:FAK	-
778365	EPZ-5676	Clinical trial	DOT1L	-
778366	EXEL-2280	Clinical trial	PK:IGF1R,AURK,FGFR,SRC	-
778367	ARRY-614	Clinical trial	PK:MAPK14	-
778368	GSK-2141795	Clinical trial	PK:AKT	-
778448	Ombrabulin	Clinical trial	TUBB\|Tu-frag	-
778590	Cobimetinib (isomer 1)	FDA approved	PK:MAP2K,MAP2K1	-
778746	FH-535	Clinical trial	PPARG	-
778747	OTX-015	Clinical trial	BRD	-
778809	TAK-632	Clinical trial	PK:BRAF	-
778810	VS-5584	Clinical trial	PK:PIK3,MTOR	-
778909	LEE-011	FDA approved	PK:CDK,CDK4,CDK6	-
779217	osimertinib	FDA approved	PK:EGFR	-
779218	CEP-28122	Clinical trial	PK:ALK	-
779404	RG-7388	Clinical trial	MDM2	-
779405	CO-1686	FDA approved	PK:EGFR	-
779407	GNE-617	Clinical trial	NAMPT	-
779408	Deltarasin	Clinical trial	PDE6D	-
780019	PD183805	Clinical trial	PK:EGFR,ERBB2	-
780020	spebrutinib	Clinical trial	PK:BTK	-
780041	GSK-126	Clinical trial	EZH2	-
780042	CP-724714	Clinical trial	PK:ERBB2	-
780043	EPZ-004777	Clinical trial	DOT1L	-
780108	PF-06463922	FDA approved	PK:ROS1,ALK	-
780163	SOMCL-12-81	Clinical trial	PK:ALK	-
780203	selinexor	FDA approved	XPO1	-
780204	TAS-116	Clinical trial	HSP90	-
780205	dimethylfasudil	Clinical trial	RHO	-
780249	AZD-6738	Clinical trial	PK:ATR	-
780250	AZD-6738 ( R,S-isomer)	Clinical trial	PK:ATR	-
780290	SAR-260301 (enantiomer 1)	Clinical trial	PI3KB	-
780291	SAR-260301 (enantiomer 1)	Clinical trial	PI3KB	-
780404	AZ-505	Clinical trial	SETD8\|SMYD2	-
780812	BMS-906024	Clinical trial	APH1\|Gamma secretase	-
780965	MK-0731	Clinical trial	CDH16\|KIF11	-
781008	maritoclax	Clinical trial	MCL1	-
781009	MI-773	Clinical trial	MDM2	-
781016	BAY-87-2243	Clinical trial	HIF1	-
781148	CEP-37440	Clinical trial	PK:ALK,FAK	-
781343	GDC-0994	Clinical trial	PK:ERK,MAP3K,MAPK1	-
781344	NMS-1286937	Clinical trial	PK:PLK1	-
781409	AGI-6780	Clinical trial	IDH2	-
781417	RN-486	Clinical trial	PK:BTK	-
781468	CUDC-427	Clinical trial	IAP	-
781469	BMS-833923	Clinical trial	SMO	-
781470	PF-03758309	Clinical trial	PK:PAK4	-
781514	AMG-925	Clinical trial	PK:CDK,CDK4,CDK6,FLT3	-
781515	AMG-232	Clinical trial	MDM2	-
781516	entosplenitib	Clinical trial	PK:SYK	-
781556	JNJ-42756493	FDA approved	PK:FGFR,FGFR1,FGFR2,FGFR3,FGFR4	-
781626	Pacritinib	Clinical trial	PK:YK,JAK,JAK2	-
781627	GSK-2606414	Clinical trial	PK:EIF2AK3	-
781652	ningetinib	Clinical trial	PK:MET	-
781761	LY-3009120	Clinical trial	PK:BRAF,RAF1	-
782006	PTC-691	Clinical trial	PK:RET	-
782007	AZ-628	Clinical trial	PK:BRAF	-
782017	H-89	Clinical trial	Protein kinase A\|PK:STK,AKT1	-
782121	volitinib	Clinical trial	PK:MET	-
782122	AMG-511	Clinical trial	PK:PIK3	-
782125	JNJ-54302833	Clinical trial	FASN	-
782153	MG-132	Clinical trial	PSM	-
782164	CX-5461	Clinical trial	RNA polymerase I	-
782310	CPI-169	Clinical trial	EZH2	-
782351	tofacitinib	FDA approved	PK:JAK,JAK1,JAK3	-
782362	PWT-33597	Clinical trial	PK:PIK3,MTOR	-
782363	CH-5183284	Clinical trial	PK:PDGFR,FGFR,VEGFR,FGFR1,FGFR2,FGFR3	-
782457	VBY-825	Clinical trial	CTSB	-
782549	Defactinib	Clinical trial	PK:FAK	-
782579	PCI-27483	Clinical trial	F7	-
782762	E-3810	Clinical trial	PK:PDGFR,FGFR,VEGFR	-
782763	cs-1730	Clinical trial	BRD	-
783015	CGM-097	Clinical trial	MDM2	-
783102	VS-4718	Clinical trial	PK:FAK	-
783107	E-7449	Clinical trial	PARP1\|PARP2	-
783249	JNJ-26483327	Clinical trial	PK:EGFR,ERBB2,SRC,VEGFR,RET,Multikinase	-
783272	JNJ-47117096	Clinical trial	PK:MELK	-
783294	VT-464	Clinical trial	CYP17A1	-
783296	poziotinib	Clinical trial	PK:EGFR,ERBB2,Multikinase	-
783332	EPZ-5687	Clinical trial	EZH2	-
783333	SGI-1027	Clinical trial	DNMT	-
783334	RG-108	Clinical trial	DNMT	-
783360	IM-25	Clinical trial	DNMT	-
783415	CB-839	Clinical trial	GLS	-
783916	pyridoclax	Clinical trial	MCL1	-
783917	GSK-2879552	Clinical trial	KDM1A	-
784284	P-1446	Clinical trial	PK:CDK,CDK1,CDK2,CDK4,CDK7,CDK9	-
784415	Danusertib	Clinical trial	BCR-ABL\|PK:YK,AURK,FGFR,RET	-
784590	altiratinib	Clinical trial	PK:MET,NTRK,VEGFR,TEK,KDR	-
784591	CCT-251545	Clinical trial	Wnt\|PK:CDK19	-
784722	aldoxorubicin	Clinical trial	TOP2	-
784815	AZD-3147	Clinical trial	PK:MTOR	-
784817	A-1210477	Clinical trial	MCL1	-
784856	CPI-0610	Clinical trial	BRD	-
785004	MLN-7243	Clinical trial	UB-activating	-
785117	PQR-309	Clinical trial	PK:PIK3,MTOR	-
785222	BMS-983970	Clinical trial	APH1\|Gamma secretase	-
785299	EPZ-015666	Clinical trial	PRMT5	-
785300	BLU-9931	Clinical trial	PK:FGFR,FGFR1,FGFR2,FGFR3,FGFR4	-
785306	TAS-115	Clinical trial	PK:MET,VEGFR	-
785345	Bet-BAY-002	Clinical trial	BRD	-
785497	INCB-024360	FDA approved	IDO1	-
785570	LOXO-101	FDA approved	PK:NTRK	-
785657	RX-3117	Clinical trial	DNMT	-
786098	BAY-1143572	Clinical trial	PK:CDK,CDK9	-
786099	AZD-8835	Clinical trial	PK:PIK3	-
786100	CB-5083	Clinical trial	VCP	-
786959	AZD-9496	Clinical trial	SERD	-
787025	BAY-1161909	Clinical trial	IDUA	-
787026	BAY-1217389	Clinical trial	IDUA	-
787027	EGF-816	Clinical trial	PK:EGFR	-
787038	AC-710	Clinical trial	PK:CSF1R,PDGFR,FLT3	-
787039	MI-503	Clinical trial	KMT2A	-
787047	AZD-3965	Clinical trial	SLC16A1\|SLC16A7	-
787048	azd5582	Clinical trial	IAP	-
787081	SR 9243	Clinical trial	NR1H1/2	-
787137	AMG-319	Clinical trial	PK:PIK3	-
787251	lomeguatrib	Clinical trial	MGMT	-
787252	TAE-226	Clinical trial	PK:IGF1R,FAK	-
787253	LY-3039478	Clinical trial	NOTCH	-
787269	SW-033291	Clinical trial	HPGD	-
787312	PT-2385	Clinical trial	EPAS1	-
787326	GDC-0810	Clinical trial	SERD	-
787457	brigatinib	FDA approved	PK:YK,IGF1R,ALK,EGFR	-
787780	sabutoclax	Clinical trial	MCL1	-
787827	CFG-920	Clinical trial	CYP17A1	-
787846	gilteritinib	FDA approved	PK:AXL,FLT3	-
787880	OTS-964	Clinical trial	PK:PBK	-
787960	UMI-77	Clinical trial	MCL1	-
787962	KU-55933	Clinical trial	PK:ATM	-
788120	enasidenib	FDA approved	IDH1\|IDH2	-
788121	AZD-3759	Clinical trial	PK:EGFR	-
788186	Bafetinib	Clinical trial	BCR-ABL\|PK:YK,FYN,LYN	-
788203	sitravatinib	Clinical trial	PK:PDGFR,AXL,NTRK,KDR,RET	-
788365	PF-06747775	Clinical trial	PK:EGFR	-
788794	A-911	Clinical trial	PK:CDK,CDK9	-
788900	napabucasin	Clinical trial	CTNNB1\|STAT3	-
788948	Vistonuridine	FDA approved	TUBB\|FU-Antidote	-
788992	OICR-9429	Clinical trial	WDR5	-
789040	CBL-0137	Clinical trial	-	-
789041	GSK-295	Clinical trial	CENP	-
789042	LOR-253	Clinical trial	KLF4\|MYC\|MTF1	-
789043	ARV-825	Clinical trial	BRD	-
789044	CCT-271850	Clinical trial	IDUA	-
789099	LY-3154567	Clinical trial	NAMPT	-
789102	ivosidenib	FDA approved	IDH1	-
789223	AMG-337	Clinical trial	PK:MET	-
789300	PLX-3397	FDA approved	PK:CSF1R,KIT,FLT3	-
789722	Litronesib	Clinical trial	TUBB\|CDH16\|KIF11	-
789797	SW-044248	Clinical trial	TOP1	-
789925	ABL-001	FDA approved	BCR-ABL	-
789968	LY-3023414	Clinical trial	PK:PIK3,MTOR	-
789969	SB-202190	Clinical trial	PK:MAPK14	-
790182	alofanib	Clinical trial	PK:FGFR	-
790865	EPZ-020411	Clinical trial	PRMT6	-
791059	MGCD-265	Clinical trial	PK:MET,VEGFR	-
791163	RG-7602	Clinical trial	PK:CHEK1	-
791164	acalabrutinib	FDA approved	PK:BTK	-
791226	SAR-245409	Clinical trial	PK:PIK3	-
791227	XL-147	Clinical trial	PK:PIK3	-
791328	ARQ-092	Clinical trial	PK:AKT	-
791495	GDC-0339	Clinical trial	PK:PIM1,PIM2,PIM3	-
791496	APR-246	Clinical trial	Apo	-
791648	PF-2771	Clinical trial	CENP	-
791783	eFT-508	Clinical trial	MKNK1/2	-
791785	Sapacitabine	Clinical trial	Ds	-
791966	CFI-400945	Clinical trial	PK:PLK1	-
791967	TAK-659 (isomer 1)	Clinical trial	PK:SYK	-
791968	TAK-659 (isomer 1)	Clinical trial	PK:SYK	-
792847	INCB-047775	Clinical trial	PK:AKT	-
792848	olmutinib	FDA approved	PK:EGFR,BTK,JAK3	-
792849	itacitinib	Clinical trial	PK:JAK1	-
792955	GSK-2194069	Clinical trial	FAS\|FASN	-
792956	AZD-0156	Clinical trial	PK:ATM	-
792969	VX-984	Clinical trial	PK:PRKDC	-
792970	KPT-9274	Clinical trial	PK:PAK4	-
792971	CC-223	Clinical trial	PK:MTOR	-
792987	GDC-0084	Clinical trial	PK:PIK3,MTOR	-
792996	ARQ-087	Clinical trial	PK:FGFR	-
792997	ARQ-087_Peak 2	Clinical trial	-	-
793103	ABBV-075	Clinical trial	BRD	-
793148	RX-5902	Clinical trial	-	-
793149	BAY-876	Clinical trial	SLC2A1	-
793150	ensartinib	Clinical trial	PK:ALK	-
793151	CC-115	Clinical trial	PK:MTOR	-
793322	naquotinib	Clinical trial	PK:EGFR	-
793323	BGB-283	Clinical trial	PK:BRAF	-
793324	BAY-1125976	Clinical trial	PK:AKT,AKT2	-
793430	CPI-1205	Clinical trial	EZH2	-
793585	LY-3177833	Clinical trial	PK:CDC7,CDK7	-
793677	ASP-5878	Clinical trial	PK:FGFR	-
793679	CNDAC	Clinical trial	-	-
793726	CCT-245737	Clinical trial	PK:CHEK1	-
793727	CCT-251921	Clinical trial	PK:CDK,CDK19	-
794109	LGH-447	Clinical trial	PK:PIM1	-
794442	PQR-620	Clinical trial	PK:MTOR	-
794443	KPT-8602	Clinical trial	XPO1	-
794487	BAY-1436032	Clinical trial	IDH1	-
794589	NTRC-0066-0	Clinical trial	PK:TTK	-
794590	BAY-1082439	Clinical trial	PK:PIK3	-
794646	AMG-51	Clinical trial	PK:MET	-
795067	IPI-549	Clinical trial	-	-
795142	M2698	Clinical trial	PK:AKT,AKT1,AKT2,AKT3	-
795384	serabelisib	Clinical trial	-	-
795718	BLU-554	Clinical trial	PK:FGFR,FGFR4	-
795781	GSK-2795039	Clinical trial	-	-
796100	PF-06840003	Clinical trial	IDO1	-
796101	ABC-294640	Clinical trial	SPHK2	-
796433	PF-04136309	Clinical trial	-	-
797172	A-1331852	Clinical trial	-	-
797393	AT-265	Clinical trial	HSP90	-
797653	WT-161	Clinical trial	HDAC	-
797769	ABC-1183	Clinical trial	-	-
797770	CEP-40783	Clinical trial	-	-
797771	ulixertinib	Clinical trial	PK:ERK	-
797772	selonsertib	Clinical trial	PK:MAP3K5	-
797932	PLX-8394	Clinical trial	PK:BRAF	-
797933	tirabrutinib	Clinical trial	PK:BTK	-
797934	Plinabulin	Clinical trial	-	-
797937	Sulfatinib	FDA approved	PK:YK,FGFR,KDR	-
797938	AZD-5153	Clinical trial	-	-
798200	TP-0903	Clinical trial	PK:AXL	-
798201	VH-298	Clinical trial	VHL	-
798202	fenebrutinib	Clinical trial	PK:BTK	-
798303	BPTES	Clinical trial	GLS	-
798304	EC-330	Clinical trial	MDM2	-
798517	SAR-20347	Clinical trial	PK:TYK2	-
798799	GS-9901	Clinical trial	-	-
798846	S-63845	Clinical trial	-	-
799644	DDP-38003	Clinical trial	-	-
799645	Aurigene Cmp 4	Clinical trial	-	-
799771	BMS-988205	Clinical trial	IDO1	-
799908	GNE-140	Clinical trial	LDHA	-
800019	PF-06821497	Clinical trial	EZH2	-
800030	LXS-196	Clinical trial	PK:PRKCA	-
800283	H3B-6527	Clinical trial	PK:FGFR	-
800404	GSK-3326595	Clinical trial	PRMT5	-
800405	umbralisib	FDA approved	-	-
800522	TPX-0005	Clinical trial	PK:ROS1,ALK	-
800525	BAY-1895344	Clinical trial	PK:ATR	-
800729	GDC-0077	Clinical trial	-	-
800888	CFI-402257	Clinical trial	IDUA\|PK:TTK	-
800890	MSC-2530818	Clinical trial	PK:CDK	-
800892	evobrutinib	Clinical trial	PK:BTK	-
800893	milademetan	Clinical trial	MDM2	-
801082	BLU-285	FDA approved	-	-
801089	PRN-1371	Clinical trial	PK:FGFR	-
801230	BMS-986158	Clinical trial	-	-
801661	TAK-931	Clinical trial	PK:CDC7	-
801812	CPI-444	Clinical trial	-	-
801813	AZD-4205	Clinical trial	PK:JAK	-
801845	-	-	-	459278582
802004	-	-	-	459276951
802100	ON-123300	Clinical trial	PK:CDK,RET	-
802101	AZD-4635	Clinical trial	-	-
802450	BAY-1251152	Clinical trial	-	-
802451	LY-3200882	Clinical trial	-	-
802548	AZD-5069	Clinical trial	CXCR2	-
802820	FT-1518	Clinical trial	PK:MTOR	-
802821	PQR-530	Clinical trial	PK:MTOR	-
802822	nedisertib	Clinical trial	-	-
803014	tenalisib	Clinical trial	-	-
803247	CB-1158	Clinical trial	-	-
803248	MTX-211	Clinical trial	PK:EGFR	-
803408	EED-226	Clinical trial	EED	-
803409	BAY-1816032	Clinical trial	PK:BUB1	-
803410	LY-3214996	Clinical trial	PK:ERK	-
803552	SGN-2FF	Clinical trial	-	-
803600	AG-881	Clinical trial	IDH1\|IDH2	-
803601	LYC-55716	Clinical trial	-	-
803789	AZD-1390	Clinical trial	PK:ATM	-
803790	Aurigene Cpm 16	Clinical trial	-	-
804040	E-7046	Clinical trial	-	-
804041	AMG-176	Clinical trial	-	-
804253	pamiparib	Clinical trial	PARP1\|PARP2	-
804254	SHP-099	Clinical trial	PTPN11	-
804518	BAY-1163877	Clinical trial	PK:FGFR	-
804520	HDM-201	Clinical trial	MDM2	-
804521	S-222611	Clinical trial	PK:EGFR,ERBB2	-
804861	ASTX-660	Clinical trial	IAP	-
804862	EPZ-031686	Clinical trial	SMYD3	-
804962	FGF-401	Clinical trial	PK:FGFR	-
805149	TP-3654	Clinical trial	PK:PIM1,PIM3	-
805500	SEL-120	Clinical trial	PK:CDK	-
805596	IDF-11774	Clinical trial	-	-
805746	CC-671	Clinical trial	PK:TTK	-
806387	CYC-065	Clinical trial	PK:CDK	-
806388	E-7090	Clinical trial	PK:FGFR	-
806595	PLX-51107	Clinical trial	-	-
806812	RG-6016	Clinical trial	-	-
807047	LXH-254	Clinical trial	PK:RAF	-
807055	AZD-5991	Clinical trial	-	-
807398	INCB-057643	Clinical trial	-	-
807626	JNJ-3887618	Clinical trial	-	-
807627	BMS-986195	Clinical trial	PK:BTK	-
808292	SGI-110	Clinical trial	DNMT	-
808507	PF-6459988	Clinical trial	PRMT5\|PK:EGFR	-
808789	RG-7741	Clinical trial	-	-
808790	AZD-0364	Clinical trial	PK:ERK	-
808792	CC-90003	Clinical trial	PK:ERK	-
809099	EPZ-011989	Clinical trial	EZH2	-
809100	RG-7112	Clinical trial	MDM2	-
809251	ETC-159	Clinical trial	-	-
809252	PF-06855800	Clinical trial	PRMT5	-
809694	BOS-172722	Clinical trial	-	-
809970	LOXO-195	Clinical trial	-	-
809971	S-64315	Clinical trial	-	-
809972	IACS-10759	Clinical trial	-	-
809973	BAY-2402234	Clinical trial	DHODH	-
810114	vecabrutinib	Clinical trial	PK:BTK	-
810341	PF-6459988	Clinical trial	PRMT5\|PK:EGFR	-
810717	CG-806	Clinical trial	PK:BTK	-
811429	BLU-667	FDA approved	PK:RET	-
811953	IACS-8968	Clinical trial	IDO1	-
812052	CH-7057288	Clinical trial	-	-
812172	ARS-1620	Clinical trial	KRAS	-
812415	ABBV-744	Clinical trial	-	-
812727	relacorilant	Clinical trial	-	-
812728	AZD-4320	Clinical trial	-	-
812901	PRN-1008	Clinical trial	PK:BTK	-
812902	-	-	-	440806897
812926	TAS-6417	Clinical trial	PK:EGFR	-
812927	PF-06873600	Clinical trial	PK:CDK	-
812928	IDH-305	Clinical trial	IDH1	-
813380	AZD-3229	Clinical trial	-	-
813381	valemetostat	Clinical trial	EZH2	-
813488	futibutinib	Clinical trial	PK:FGFR	-
813783	Trabectedin	FDA approved	A2	-
813859	RGX-104	Clinical trial	-	-
813862	Lapachone	Clinical trial	TOP2\|TOP1	-
814025	LSZ-102	Clinical trial	SERD	-
816024	-	-	-	440815726
816437	-	-	-	440816497
816554	-	-	-	440796500
816555	-	-	-	440795955
816556	-	-	-	440804240
816863	-	-	-	440815048
816987	-	-	-	440795760
817040	-	-	-	440810316
817041	-	-	-	440797093
817042	-	-	-	440798549
817043	-	-	-	440812305
818002	-	-	-	440798412
818003	-	-	-	440798565
818432	-	-	-	440798552
818433	-	-	-	440796328
818434	-	-	-	440798555
818435	-	-	-	440798527
818619	-	-	-	440807030
818620	-	-	-	440804300
818621	-	-	-	440808209
819210	-	-	-	440806890
819211	-	-	-	440812602
819558	-	-	-	440798408
820052	-	-	-	440809833
820283	-	-	-	440802431
820784	-	-	-	440799577
820832	-	-	-	440798529
820918	-	-	-	440798792
820919	-	-	-	440807423
821656	-	-	-	440810462
822744	-	-	-	440809732
823658	-	-	-	440812495
823659	-	-	-	440815776
823806	-	-	-	440802233
823807	-	-	-	440796275
824183	-	-	-	440814994
824184	-	-	-	440799266
824722	-	-	-	440801661
824723	-	-	-	440795818
825088	-	-	-	440807533
825089	-	-	-	440804121
825217	-	-	-	440799301
825254	-	-	-	440801555
825282	-	-	-	440802755
825286	-	-	-	440816002
825287	-	-	-	440813265
825331	-	-	-	440796129
825332	-	-	-	440804307
825519	-	-	-	440802469
825520	-	-	-	440805236
825521	-	-	-	440813474
825522	-	-	-	440807937
825523	-	-	-	440816160
825713	-	-	-	440800094
825775	-	-	-	440796922
825827	-	-	-	440800120
825956	-	-	-	440799812
826039	-	-	-	440800033
826040	-	-	-	440797119
826119	-	-	-	440797111
826275	-	-	-	440802518
826942	-	-	-	440813546
827275	-	-	-	440805393
827675	-	-	-	440808421
827676	-	-	-	440816625
827802	-	-	-	440813863
827886	-	-	-	440814015
828250	-	-	-	440802509
828251	-	-	-	440799695
828252	-	-	-	440807963
828316	-	-	-	440816194
828317	-	-	-	440796775
828318	-	-	-	440799724
828319	-	-	-	440796816
828583	-	-	-	440805582
828584	-	-	-	440797141
828717	-	-	-	440802545
828852	-	-	-	440811289
828853	-	-	-	440797285
828939	-	-	-	441612643
829066	-	-	-	441613449
829498	-	-	-	441613247
830173	-	-	-	441614055
830201	-	-	-	441612883
830202	-	-	-	441613877
830368	-	-	-	441612832
830911	-	-	-	441612801
830912	-	-	-	441613985
831147	-	-	-	441613338
831270	-	-	-	441613161
831271	-	-	-	441613761
831453	-	-	-	443699379
831868	-	-	-	443698476
832046	-	-	-	443698883
832261	-	-	-	443699440
832262	-	-	-	443699552
832263	-	-	-	443698610
832522	-	-	-	443699273
832523	-	-	-	443698716
832772	-	-	-	459277194
832937	-	-	-	459278590
832938	-	-	-	459277772
833292	-	-	-	459277627
833390	-	-	-	459277077
833745	-	-	-	459278422
833746	-	-	-	459278165
833899	-	-	-	459277050
833900	-	-	-	459278419
833901	-	-	-	459278703
833973	-	-	-	459278474
834160	-	-	-	459277646
834161	-	-	-	459278460
834196	-	-	-	459278740
834197	-	-	-	459278456
834374	-	-	-	459277103
834375	-	-	-	459277916
835418	-	-	-	459277475
835419	-	-	-	459278290
835563	-	-	-	459328201
835773	-	-	-	459636785
835774	-	-	-	459636828
835775	-	-	-	459636907
835776	-	-	-	459636991
835817	-	-	-	459636909
835818	-	-	-	459636738
836049	-	-	-	461477656
836050	-	-	-	461477664
836163	-	-	-	461483243
836407	-	-	-	461593900
836439	-	-	-	461650707
836440	-	-	-	461650696
836824	-	-	-	461650746
836941	-	-	-	461663123
836942	-	-	-	461663096
837081	-	-	-	461823403
837082	-	-	-	461823418
837396	-	-	-	462764937
837397	-	-	-	462764921
837398	-	-	-	462764928
837893	-	-	-	463821130
838377	-	-	-	464113151
838762	-	-	-	464868654
838763	-	-	-	464868809
839053	-	-	-	469398763
839102	-	-	-	469128523
839303	Triptolide	-	-	469691020
839697	-	-	-	470142021
839698	-	-	-	470142005
839699	-	-	-	470141998
839865	-	-	-	470142042
839866	-	-	-	470142011