| Gene symbol | Annotations |
| ACVR2A | mesoderm development; determination of left/right symmetry; BMP signaling pathway; positive regulation of bone mineralization; response to organic substance; anterior/posterior pattern specification; spermatogenesis; transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of protein phosphorylation; gastrulation with mouth forming second; regulation of BMP signaling pathway; activin receptor signaling pathway; Sertoli cell proliferation; regulation of nitric-oxide synthase activity; embryonic skeletal system development; positive regulation of follicle-stimulating hormone secretion; positive regulation of osteoblast differentiation; positive regulation of erythrocyte differentiation; penile erection; sperm ejaculation; positive regulation of activin receptor signaling pathway | |
| ADNP | response to inorganic substance; positive regulation of synapse assembly; response to carbohydrate stimulus; short-term memory; negative regulation of gene expression; regulation of protein ADP-ribosylation; positive regulation of neuron projection development; positive regulation of cGMP biosynthetic process; nitric oxide homeostasis; negative regulation of synaptic transmission; negative regulation of neuron apoptosis; cellular response to extracellular stimulus; positive regulation of axon extension; estrous cycle phase; negative regulation of protein binding; activation of protein kinase activity; neuroprotection; positive regulation of peptidyl-tyrosine phosphorylation | |
| AKAP5 | regulation of insulin secretion; energy reserve metabolic process; protein targeting; signal transduction; synaptic transmission; positive regulation of protein kinase A signaling cascade; positive regulation of cAMP biosynthetic process; small molecule metabolic process | |
| AKAP8 | signal transduction; mitotic chromosome condensation; mitosis | |
| ANXA1 | cell surface receptor signaling pathway; keratinocyte differentiation; insulin secretion; peptide cross-linking; response to organic cyclic compound; response to X-ray; response to peptide hormone stimulus; endocrine pancreas development; positive regulation of vesicle fusion; positive regulation of prostaglandin biosynthetic process; response to estradiol stimulus; gliogenesis; regulation of cell proliferation; response to drug; positive regulation of apoptotic process; negative regulation of apoptotic process; alpha-beta T cell differentiation; arachidonic acid secretion; negative regulation of protein secretion; response to glucocorticoid stimulus; estrous cycle phase; cellular response to hydrogen peroxide; hepatocyte differentiation; response to interleukin-1; cell cycle; inflammatory response; cellular component movement; anti-apoptosis; lipid metabolic process; negative regulation of acute inflammatory response; signal transduction | |
| ANXA2 | angiogenesis; skeletal system development; body fluid secretion; collagen fibril organization; positive regulation of vesicle fusion; fibrinolysis; positive regulation of binding; cellular response to acid | |
| ANXA4 | negative regulation of coagulation; signal transduction; anti-apoptosis | |
| AP2M1 | negative regulation of epidermal growth factor receptor signaling pathway; vesicle-mediated transport; nerve growth factor receptor signaling pathway; cellular membrane organization; viral reproduction; axon guidance; synaptic transmission; epidermal growth factor receptor signaling pathway; intracellular protein transport; transport; regulation of defense response to virus by virus | |
| ATXN2 | regulation of translation; cell death; RNA metabolic process; cytoplasmic mRNA processing body assembly; stress granule assembly; negative regulation of multicellular organism growth; neuron projection morphogenesis; homeostasis of number of cells; RNA transport; neuromuscular process; cerebellar Purkinje cell differentiation | |
| BCAR1 | cell adhesion; regulation of cell growth; actin filament organization; insulin receptor signaling pathway; cell migration; signal transduction; cell division; B cell receptor signaling pathway; G-protein coupled receptor signaling pathway; epidermal growth factor receptor signaling pathway; integrin-mediated signaling pathway; T cell receptor signaling pathway; antigen receptor-mediated signaling pathway; hepatocyte growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; vascular endothelial growth factor receptor signaling pathway; platelet-derived growth factor receptor signaling pathway; regulation of apoptotic process; cellular response to hepatocyte growth factor stimulus; positive regulation of cell migration; platelet activation; cell chemotaxis; blood coagulation; cell proliferation | |
| CASP2 | luteolysis; execution phase of apoptosis; apoptotic signaling pathway; cellular response to mechanical stimulus; nerve growth factor receptor signaling pathway; positive regulation of neuron apoptosis; positive regulation of apoptotic process; protein processing; induction of apoptosis by extracellular signals; metabolic process; aging; brain development; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; proteolysis; neural retina development | |
| CASP7 | positive regulation of neuron apoptosis; release of cytochrome c from mitochondria; protein processing; response to UV; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; induction of apoptosis by intracellular signals; aging; heart development; cellular component disassembly involved in apoptosis; induction of apoptosis; apoptotic process; proteolysis | |
| CCNA2 | mitotic cell cycle G2/M transition DNA damage checkpoint; cell division; positive regulation of transcription, DNA-dependent; Ras protein signal transduction; mitosis; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity | |
| CCNB1 | cell division; digestive tract development; response to DDT; positive regulation of mitotic cell cycle; mitotic spindle stabilization; response to drug; tissue regeneration; positive regulation of histone phosphorylation; positive regulation of mRNA 3'-end processing; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of gene expression; response to mechanical stimulus; spermatogenesis; mitotic metaphase plate congression; protein complex assembly; negative regulation of protein phosphorylation; in utero embryonic development; oocyte maturation; mitotic cell cycle; mitotic prometaphase; G2/M transition of mitotic cell cycle; G1/S transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; cell cycle checkpoint; response to toxin; positive regulation of cardiac muscle cell proliferation; regulation of chromosome condensation; ventricular cardiac muscle cell development; mitotic cell cycle spindle checkpoint; cellular | |
| CD46 | complement activation, classical pathway; single fertilization; interspecies interaction between organisms; innate immune response | |
| CDH1 | cellular component disassembly involved in apoptosis; apoptotic process; cellular response to indole-3-methanol; cellular response to lithium ion; regulation of immune response; positive regulation of transcription, DNA-dependent; cell-cell junction organization; positive regulation of transcription factor import into nucleus; response to drug; adherens junction organization; cell junction assembly; neuron projection development; negative regulation of cell-cell adhesion; pituitary gland development; cell-cell adhesion; response to organic substance; response to toxin; synapse assembly; homophilic cell adhesion; cell adhesion | |
| CDH2 | striated muscle cell differentiation; positive regulation of muscle cell differentiation; negative regulation of canonical Wnt receptor signaling pathway; regulation of axonogenesis; blood vessel morphogenesis; cell-cell junction organization; positive regulation of MAPK cascade; muscle cell differentiation; regulation of Rho protein signal transduction; adherens junction organization; regulation of protein localization; regulation of myelination; cell migration; calcium-dependent cell-cell adhesion; synapse assembly; heterophilic cell-cell adhesion; cell adhesion; cell junction assembly; homophilic cell adhesion | |
| CDH3 | cell-cell junction organization; cell adhesion; homophilic cell adhesion; visual perception; cell junction assembly; adherens junction organization; response to stimulus | |
| CDK1 | protein localization to kinetochore; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of protein import into nucleus, translocation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; organ regeneration; chromosome condensation; cell migration; response to activity; response to amine stimulus; response to organic cyclic compound; regulation of Schwann cell differentiation; positive regulation of gene expression; response to toxin; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; response to copper ion; cellular response to hydrogen peroxide; positive regulation of cardiac muscle cell proliferation; ventricular cardiac muscle cell development; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic | |
| CDK4 | cell division; regulation of cell cycle; positive regulation of fibroblast proliferation; response to drug; regulation of gene expression; positive regulation of cell proliferation; cell cycle; protein phosphorylation; mitotic cell cycle; S phase of mitotic cell cycle; signal transduction; G1/S transition of mitotic cell cycle; G1 phase of mitotic cell cycle | |
| CDK5 | negative regulation of transcription, DNA-dependent; positive regulation of protein kinase activity; negative regulation of cell cycle; regulated secretory pathway; positive regulation of neuron apoptosis; receptor clustering; regulation of apoptotic process; synaptic transmission, glutamatergic; serine phosphorylation of STAT3 protein; receptor catabolic process; negative regulation of synaptic plasticity; negative regulation of protein ubiquitination; neuron projection development; cortical actin cytoskeleton organization; dendrite morphogenesis; regulation of cell migration; positive regulation of calcium ion-dependent exocytosis; protein autophosphorylation; negative regulation of protein export from nucleus; behavioral response to cocaine; regulation of synaptic plasticity; synaptic vesicle endocytosis; axon extension; oligodendrocyte differentiation; cell division; neuron apoptosis; regulation of excitatory postsynaptic membrane potential; regulation of dendritic spine morphogenesis; regulation of cell | |
| CDK6 | hemopoiesis; gliogenesis; cell dedifferentiation; negative regulation of cell differentiation; negative regulation of myeloid cell differentiation; regulation of erythrocyte differentiation; negative regulation of osteoblast differentiation; negative regulation of cell cycle; positive regulation of fibroblast proliferation; generation of neurons; negative regulation of epithelial cell proliferation; cell division; regulation of cell motility; negative regulation of cellular senescence; dentate gyrus development; lateral ventricle development; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; mitotic cell cycle; positive regulation of cell-matrix adhesion; type B pancreatic cell development; protein phosphorylation; cell cycle; cell cycle arrest; negative regulation of cell proliferation; response to virus; regulation of gene expression; astrocyte development | |
| CDK7 | transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; mRNA capping; protein phosphorylation; cell cycle arrest; cell proliferation; gene expression; viral reproduction; androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; cell division; termination of RNA polymerase I transcription; regulation of cyclin-dependent protein kinase activity; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; mitotic cell cycle; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; transcription from RNA polymerase II promoter; nucleotide-ex | |
| CDKN2A | senescence-associated heterochromatin focus assembly; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cyclin-dependent protein kinase activity; positive regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of phosphorylation; protein stabilization; positive regulation of smooth muscle cell apoptosis; positive regulation of protein sumoylation; negative regulation of immature T cell proliferation in thymus; regulation of protein export from nucleus; somatic stem cell division; negative regulation of ubiquitin-protein ligase activity; protein K63-linked ubiquitination; positive regulation of cell cycle arrest; cellular senescence; replicative senescence; positive regulation of macrophage apoptosis; positive regulation of cellular senescence; activation of cysteine-type endopeptidase activity involved in apoptotic proce | |
| CRK | insulin receptor signaling pathway; platelet activation; regulation of Rho GTPase activity; regulation of actin cytoskeleton organization; regulation of Rac protein signal transduction; nerve growth factor receptor signaling pathway; ephrin receptor signaling pathway; blood coagulation; regulation of transcription from RNA polymerase II promoter; activation of MAPKK activity | |
| CTNNB1 | negative regulation of transcription, DNA-dependent; positive regulation of osteoblast differentiation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to cadmium ion; regulation of fibroblast proliferation; determination of dorsal/ventral asymmetry; cell maturation; synaptic vesicle transport; thymus development; oocyte development; embryonic foregut morphogenesis; regulation of smooth muscle cell proliferation; negative regulation of oligodendrocyte differentiation; positive regulation of anti-apoptosis; regulation of angiogenesis; positive regulation of fibroblast growth factor receptor signaling pathway; negative regulation of osteoclast differentiation; canonical Wnt receptor signaling pathway; positive regulation of endothelial cell differentiation; bone resorption; myoblast differentiation; canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis; canonical Wnt receptor signaling pathway inv | |
| CTTN | - | |
| DSG1 | apoptotic process; cellular component disassembly involved in apoptosis; cell-cell junction assembly; homophilic cell adhesion; cell-cell adhesion; calcium-dependent cell-cell adhesion; protein stabilization | |
| ENAH | actin polymerization or depolymerization; T cell receptor signaling pathway; neural tube closure; cellular component movement; axon guidance; intracellular transport | |
| EP300 | positive regulation of sequence-specific DNA binding transcription factor activity; response to ethanol; positive regulation of translation; positive regulation of axon extension; positive regulation of cell size; innate immune response; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; digestive tract development; positive regulation of protein secretion; negative regulation of transcription from RNA polymerase II promoter; response to glucocorticoid stimulus; response to calcium ion; regulation of angiotensin metabolic process; positive regulation of sarcomere organization; regulation of androgen receptor signaling pathway; protein-DNA complex assembly; cellular response to hydrogen peroxide; response to fatty acid; nervous system development; N-terminal peptidyl-lysine acetylation; histone acetylation; response to organic cyclic compound; positive regulation of glycoprotein biosynthetic process; organ morphogenesis; response to glucose stimulus; skele | |
| ERBB2 | positive regulation of transcription from RNA polymerase III promoter; positive regulation of protein phosphorylation; negative regulation of immature T cell proliferation in thymus; regulation of microtubule-based process; response to progesterone stimulus; positive regulation of Rho GTPase activity; mammary gland development; positive regulation of cell growth; signal transduction by phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase cascade; glial cell differentiation; cell proliferation; motor axon guidance; liver development; wound healing; regulation of transcription, DNA-dependent; protein phosphorylation; signal transduction; cell surface receptor signaling pathway; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; epidermal growth factor receptor signaling pathway; nervous system development; axon guidance; peripheral nervous system development; heart development; skeletal muscl | |
| ESR1 | uterus development; vagina development; prostate epithelial cord elongation; regulation of branching involved in prostate gland morphogenesis; mammary gland branching involved in pregnancy; mammary gland alveolus development; epithelial cell proliferation involved in mammary gland duct elongation; positive regulation of ERK1 and ERK2 cascade; cellular response to estrogen stimulus; antral ovarian follicle growth; epithelial cell development; osteoblast development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; signal transduction; androgen metabolic process; gene expression; negative regulation of gene expression; intracellular estrogen receptor signaling pathway; response to estradiol stimulus; regulation of apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; Sertoli cell proliferation; steroid hormone mediated signaling pathway; negative regulation of sequence-specific DNA binding transcription factor activity; neuroprotection; response to estrogen stimul | |
| EXOC4 | membrane biogenesis; protein targeting to membrane; vesicle docking involved in exocytosis; synaptic transmission; establishment of cell polarity; oligodendrocyte differentiation; positive regulation of calcium-mediated signaling; regulation of protein transport; Golgi to transport vesicle transport | |
| EZR | actin filament bundle assembly; establishment or maintenance of apical/basal cell polarity; epithelial cell differentiation; membrane to membrane docking; regulation of cell shape; axon guidance; leukocyte cell-cell adhesion; cytoskeletal anchoring at plasma membrane | |
| FADD | cellular response to mechanical stimulus; positive regulation of apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; extrinsic apoptotic signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; interspecies interaction between organisms; innate immune response; induction of apoptosis by extracellular signals; induction of apoptosis via death domain receptors; activation of pro-apoptotic gene products; positive regulation of interleukin-8 production; positive regulation of transcription from RNA polymerase II promoter; defense response to virus; positive regulation of type I interferon-mediated signaling pathway; necrotic cell death; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; positive regulation of tumor necrosis factor production | |
| FASLG | induction of apoptosis; apoptotic process; activation of pro-apoptotic gene products; response to growth factor stimulus; activation of cysteine-type endopeptidase activity involved in apoptotic process; inflammatory cell apoptosis; signal transduction; induction of apoptosis via death domain receptors; negative regulation of angiogenesis; cellular chloride ion homeostasis; response to lipopolysaccharide; cellular response to stress; positive regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of neuron apoptosis; positive regulation of epidermal growth factor receptor signaling pathway; retinal cell programmed cell death; endosomal lumen acidification; induction of necroptosis of activated-T cells; induction of necroptosis by extracellular signals; necrotic cell death; immune response; cell-cell signaling; positive regulation of cell proliferation; induction of apoptosis by extracellular signals | |
| FN1 | angiogenesis; leukocyte migration; substrate adhesion-dependent cell spreading; platelet activation; peptide cross-linking; cell migration; regulation of cell shape; blood coagulation; cell adhesion; acute-phase response; platelet degranulation; response to wounding | |
| GRB2 | cell differentiation; fibroblast growth factor receptor signaling pathway; cell-cell signaling; platelet activation; epidermal growth factor receptor signaling pathway; T cell costimulation; receptor internalization; Ras protein signal transduction; negative regulation of epidermal growth factor receptor signaling pathway; signal transduction in response to DNA damage; regulation of MAPK cascade; interspecies interaction between organisms; axon guidance; nerve growth factor receptor signaling pathway; anatomical structure formation involved in morphogenesis; aging; leukocyte migration; protein heterooligomerization; blood coagulation; branching involved in embryonic placenta morphogenesis; cellular response to ionizing radiation; insulin receptor signaling pathway; positive regulation of reactive oxygen species metabolic process | |
| GSK3B | positive regulation of protein complex assembly; cell differentiation; negative regulation of protein binding; positive regulation of Rac GTPase activity; regulation of microtubule-based process; intracellular signal transduction; negative regulation of apoptotic process; negative regulation of glycogen biosynthetic process; positive regulation of protein catabolic process; positive regulation of protein export from nucleus; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; negative regulation of NFAT protein import into nucleus; canonical Wnt receptor signaling pathway; superior temporal gyrus development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of type B pancreatic cell development; negative regulation of glycogen (starch) synthase activity; negative regulation of protein complex assembly; epithelial to mesenchymal transition; positive regulation of cell-matrix adhesion; carbohydrate metabolic process; glycogen metabolic pro | |
| GSTP1 | response to toxin; response to reactive oxygen species; negative regulation of acute inflammatory response; negative regulation of protein kinase activity; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; response to amino acid stimulus; negative regulation of MAP kinase activity; negative regulation of MAPK cascade; negative regulation of JUN kinase activity; small molecule metabolic process; response to ethanol; negative regulation of fibroblast proliferation; xenobiotic metabolic process; negative regulation of necrotic cell death; regulation of ERK1 and ERK2 cascade; negative regulation of ERK1 and ERK2 cascade; negative regulation of leukocyte proliferation; cellular response to lipopolysaccharide; cellular response to epidermal growth factor stimulus; cellular response to glucocorticoid stimulus; cellular response to cell-matrix adhesion; negative regulation of monocyte chemotactic prote | |
| GTF2B | viral reproduction; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; interspecies interaction between organisms | |
| HRAS | positive regulation of transcription from RNA polymerase II promoter; leukocyte migration; positive regulation of DNA replication; negative regulation of neuron apoptosis; social behavior; positive regulation of Rac protein signal transduction; regulation of synaptic transmission, GABAergic; mitotic cell cycle G1/S transition checkpoint; actin cytoskeleton organization; positive regulation of JNK cascade; nerve growth factor receptor signaling pathway; regulation of long-term neuronal synaptic plasticity; positive regulation of epithelial cell proliferation; striated muscle cell differentiation; positive regulation of ERK1 and ERK2 cascade; cellular senescence; positive regulation of MAPK cascade; cell surface receptor signaling pathway; organ morphogenesis; chemotaxis; apoptotic process; endocytosis; positive regulation of protein phosphorylation; activation of MAPKK activity; cell cycle arrest; signal transduction; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction | |
| HSPA4 | protein import into mitochondrial outer membrane; response to stress; response to unfolded protein; response to heat; positive regulation of protein binding; chaperone-mediated protein complex assembly | |
| HSPD1 | isotype switching to IgG isotypes; protein stabilization; positive regulation of T cell activation; chaperone-mediated protein complex assembly; protein maturation; MyD88-dependent toll-like receptor signaling pathway; B cell cytokine production; protein refolding; positive regulation of T cell mediated immune response to tumor cell; ATP catabolic process; 'de novo' protein folding; activation of cysteine-type endopeptidase activity involved in apoptotic process; response to unfolded protein; cell death; positive regulation of interferon-alpha production; positive regulation of interferon-gamma production; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; positive regulation of interleukin-6 production; interspecies interaction between organisms; B cell proliferation; T cell activation; B cell activation; positive regulation of macrophage activation; positive regulation of apoptotic process; negative regulation of apoptotic process | |
| IRF9 | type I interferon-mediated signaling pathway; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; cell surface receptor signaling pathway; response to virus; cytokine-mediated signaling pathway; type I interferon biosynthetic process; interferon-gamma-mediated signaling pathway | |
| IRS1 | response to peptide hormone stimulus; positive regulation of phosphatidylinositol 3-kinase activity; glucose homeostasis; positive regulation of phosphorylation; protein localization to nucleus; cellular response to insulin stimulus; response to insulin stimulus; positive regulation of fatty acid beta-oxidation; mammary gland development; positive regulation of cell migration; lipid catabolic process; phosphatidylinositol 3-kinase cascade; positive regulation of glucose metabolic process; regulation of gene expression; insulin receptor signaling pathway; positive regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; positive regulation of mesenchymal cell proliferation; protein kinase B signaling cascade; negative regulation of somatostatin secretion; positive regulation of glucagon secretion; JAK-STAT cascade involved in growth hormone signaling pathway; protein heterooligomerization; phosphatidylinositol-mediated signaling; nerve growth fact | |
| JAK1 | response to antibiotic; intracellular signal transduction; type I interferon-mediated signaling pathway; cytokine-mediated signaling pathway; peptidyl-tyrosine phosphorylation; intracellular protein kinase cascade; enzyme linked receptor protein signaling pathway; interferon-gamma-mediated signaling pathway; protein phosphorylation; regulation of interferon-gamma-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway | |
| KLK3 | negative regulation of angiogenesis; proteolysis | |
| KRT18 | interspecies interaction between organisms; negative regulation of apoptotic process; Golgi to plasma membrane CFTR protein transport; tumor necrosis factor-mediated signaling pathway; anatomical structure morphogenesis; cell cycle | |
| KRT19 | cell differentiation involved in embryonic placenta development; response to estrogen stimulus; interspecies interaction between organisms; sarcomere organization | |
| KRT20 | apoptotic process; cellular response to stress; intermediate filament organization; regulation of protein secretion | |
| KRT7 | interphase; interspecies interaction between organisms; cytoskeleton organization; regulation of translation; DNA replication | |
| KRT8 | cytoskeleton organization; interspecies interaction between organisms | |
| MAP2K1 | toll-like receptor 4 signaling pathway; nerve growth factor receptor signaling pathway; vesicle transport along microtubule; response to axon injury; positive regulation of Ras protein signal transduction; positive regulation of cell differentiation; innate immune response; TRIF-dependent toll-like receptor signaling pathway; signal transduction; neuron projection morphogenesis; cell motility; response to glucocorticoid stimulus; stress-activated MAPK cascade; placenta blood vessel development; labyrinthine layer development; regulation of Golgi inheritance; cellular senescence; axon guidance; Ras protein signal transduction; small GTPase mediated signal transduction; regulation of early endosome to late endosome transport; MAPK cascade; epidermal growth factor receptor signaling pathway; regulation of stress-activated MAPK cascade; neuron differentiation; melanosome transport; positive regulation of Ras GTPase activity; mitosis; positive regulation of cell migration; keratinocyte differentiation; cell cycle | |
| MAP2K2 | MyD88-independent toll-like receptor signaling pathway; axon guidance; Ras protein signal transduction; small GTPase mediated signal transduction; epidermal growth factor receptor signaling pathway; protein phosphorylation; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; activation of MAPK activity; activation of MAPKK activity; MAPK cascade; Toll signaling pathway; toll-like receptor 3 signaling pathway; stress-activated MAPK cascade; ERK1 and ERK2 cascade; regulation of Golgi inheritance; positive regulation of cell motility; regulation of early endosome to late endosome transport; nerve growth factor receptor signaling pathway; innate immune response; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 2 signaling pathway; fibroblast growth factor receptor signaling pathway; regulation of stress-activated MAPK cascade; insulin receptor signaling pathway; toll-like receptor 1 signaling pathway | |
| MAPK1 | MAPK cascade; TRIF-dependent toll-like receptor signaling pathway; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of translation; negative regulation of cell differentiation; innate immune response; interspecies interaction between organisms; response to estrogen stimulus; response to exogenous dsRNA; T cell receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; mammary gland epithelial cell proliferation; regulation of stress-activated MAPK cascade; response to lipopolysaccharide; lipopolysaccharide-mediated signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; activation of MAPKK activity; activation of MAPK activity; MAPK import into nucleus; regulation of early endosome to late endosome transport; regulation of Golgi inheritance; caveolin-mediated endocytosis; ERK1 and ERK2 | |
| MCC | signal transduction; negative regulation of epithelial cell migration; Wnt receptor signaling pathway; negative regulation of epithelial cell proliferation; negative regulation of canonical Wnt receptor signaling pathway | |
| MCM7 | cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; DNA-dependent DNA replication initiation; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA unwinding involved in replication; DNA strand elongation involved in DNA replication; response to DNA damage stimulus; cell proliferation; regulation of phosphorylation; DNA replication | |
| MGMT | response to drug; cellular response to ionizing radiation; cellular response to organic cyclic compound; mammary gland epithelial cell differentiation; negative regulation of cell death; response to folic acid; positive regulation of DNA repair; response to ethanol; DNA repair; DNA methylation; DNA dealkylation involved in DNA repair; response to toxin; methylation; cellular response to oxidative stress; regulation of cysteine-type endopeptidase activity involved in apoptotic process; DNA ligation | |
| MLH1 | reciprocal meiotic recombination; spindle midzone assembly involved in meiosis; cellular response to organic cyclic compound; pachytene; nuclear-transcribed mRNA poly(A) tail shortening; resolution of meiotic recombination intermediates; response to hypoxia; ATP catabolic process; mismatch repair; double-strand break repair via nonhomologous end joining; cell cycle; male meiosis chromosome segregation; spermatogenesis; DNA damage response, signal transduction resulting in induction of apoptosis; oogenesis; negative regulation of mitotic recombination; isotype switching; meiotic metaphase I plate congression; response to drug; somatic hypermutation of immunoglobulin genes; response to toxin | |
| MSH2 | somatic hypermutation of immunoglobulin genes; positive regulation of helicase activity; negative regulation of DNA recombination; isotype switching; negative regulation of reciprocal meiotic recombination; maintenance of DNA repeat elements; negative regulation of neuron apoptosis; response to amino acid stimulus; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; response to drug; intra-S DNA damage checkpoint; B cell differentiation; B cell mediated immunity; somatic recombination of immunoglobulin gene segments; ATP catabolic process; DNA repair; postreplication repair; response to organic cyclic compound; meiotic mismatch repair; in utero embryonic development; oxidative phosphorylation; response to UV-B; response to X-ray; male gonad development; determination of adult lifespan; spermatogenesis; germ cell development; cell cycle arrest; meiotic gene conversion; double-strand break repair; mismatch repair | |
| MSH6 | meiotic mismatch repair; positive regulation of helicase activity; determination of adult lifespan; induction of apoptosis by intracellular signals; DNA damage response, signal transduction resulting in induction of apoptosis; response to UV; reciprocal meiotic recombination; mismatch repair; DNA repair; ATP catabolic process; somatic hypermutation of immunoglobulin genes; somatic recombination of immunoglobulin gene segments; maintenance of DNA repeat elements; isotype switching; negative regulation of DNA recombination | |
| MSN | cellular component movement; leukocyte cell-cell adhesion; membrane to membrane docking; leukocyte migration; regulation of lymphocyte migration | |
| MVP | protein transport; response to drug; mRNA transport | |
| NCAM1 | interferon-gamma-mediated signaling pathway; positive regulation of calcium-mediated signaling; homotypic cell-cell adhesion; cytokine-mediated signaling pathway; axon guidance; cell adhesion | |
| NME1 | nervous system development; nucleobase-containing small molecule metabolic process; response to cAMP; positive regulation of epithelial cell proliferation; small molecule metabolic process; positive regulation of DNA binding; regulation of apoptotic process; response to drug; cell differentiation; nucleotide metabolic process; negative regulation of cell proliferation; lactation; endocytosis; CTP biosynthetic process; UTP biosynthetic process; GTP biosynthetic process; nucleoside diphosphate phosphorylation; negative regulation of myeloid leukocyte differentiation; nucleobase-containing small molecule interconversion | |
| PARP1 | protein poly-ADP-ribosylation; DNA damage response, detection of DNA damage; regulation of growth rate; cellular response to insulin stimulus; protein autoprocessing; protein ADP-ribosylation; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; base-excision repair; DNA repair; telomere maintenance | |
| PCNA | regulation of DNA replication; intracellular protein transport; mismatch repair; nucleotide-excision repair, DNA gap filling; base-excision repair, gap-filling; base-excision repair; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; DNA strand elongation involved in DNA replication; DNA replication; telomere maintenance; telomere maintenance via recombination; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; S phase of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell proliferation; translesion synthesis; positive regulation of deoxyribonuclease activity; heart development; telomere maintenance via semi-conservative replication; response to lipid; response to cadmium ion; phosphatidylinositol-mediated signaling | |
| PGR | negative regulation of gene expression; mammary gland development; tertiary branching involved in mammary gland duct morphogenesis; steroid hormone mediated signaling pathway; regulation of epithelial cell proliferation; progesterone receptor signaling pathway; gene expression; cell-cell signaling; signal transduction; epithelial cell maturation; ovulation from ovarian follicle | |
| PRKCA | energy reserve metabolic process; fibroblast growth factor receptor signaling pathway; positive regulation of lipopolysaccharide-mediated signaling pathway; platelet activation; mRNA metabolic process; RNA metabolic process; positive regulation of cardiac muscle hypertrophy; positive regulation of endothelial cell migration; gene expression; induction of apoptosis by extracellular signals; negative regulation of glial cell apoptosis; blood coagulation; synaptic transmission; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; apoptotic process; protein phosphorylation; positive regulation of endothelial cell proliferation; histone H3-T6 phosphorylation; positive regulation of dense core granule biogenesis; regulation of platelet aggregation; response to interleukin-1; positive regulation of ERK1 and ERK2 cascade; regulation of insulin secretion; nerve growth factor receptor signaling pathway; positive regulation of mitotic cell cycle; positive regul | |
| PRKCB | apoptotic process; signal transduction; protein phosphorylation; regulation of transcription from RNA polymerase II promoter; synaptic transmission; blood coagulation; positive regulation of NF-kappaB transcription factor activity; positive regulation of B cell receptor signaling pathway; B cell receptor signaling pathway; negative regulation of insulin receptor signaling pathway; positive regulation of angiogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; lipoprotein transport; B cell activation; intracellular signal transduction; histone H3-T6 phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; platelet activation; chromatin modification; negative regulation of glucose transport | |
| PRKCH | intracellular signal transduction; positive regulation of keratinocyte differentiation; positive regulation of B cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; positive regulation of glial cell proliferation; regulation of tight junction assembly; negative regulation of glial cell apoptosis; platelet activation; cell differentiation; positive regulation of macrophage derived foam cell differentiation; blood coagulation; signal transduction; protein phosphorylation | |
| PRKCI | actin filament organization; protein targeting to membrane; cytoskeleton organization; positive regulation of neuron projection development; protein phosphorylation; cellular membrane organization; vesicle-mediated transport; cellular response to insulin stimulus; cell junction assembly; negative regulation of glial cell apoptosis; establishment of apical/basal cell polarity; intracellular signal transduction; eye photoreceptor cell development; response to peptide hormone stimulus; negative regulation of neuron apoptosis; cell-cell junction organization; anti-apoptosis; establishment or maintenance of epithelial cell apical/basal polarity; positive regulation of endothelial cell apoptosis; positive regulation of establishment of protein localization in plasma membrane; tight junction assembly; response to interleukin-1; positive regulation of glial cell proliferation; positive regulation of NF-kappaB transcription factor activity; Golgi vesicle budding; nerve growth factor receptor signaling pathway; secreti | |
| PRSS8 | proteolysis; response to mineralocorticoid stimulus; response to peptide hormone stimulus; response to drug; positive regulation of sodium ion transport; hair follicle development | |
| PTPN11 | regulation of cell adhesion mediated by integrin; T cell costimulation; cytokine-mediated signaling pathway; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; blood coagulation; axon guidance; epidermal growth factor receptor signaling pathway; peptidyl-tyrosine dephosphorylation; ephrin receptor signaling pathway; leukocyte migration; interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway | |
| PTPN6 | JAK-STAT cascade involved in growth hormone signaling pathway; regulation of type I interferon-mediated signaling pathway; regulation of ERK1 and ERK2 cascade; regulation of G1/S transition of mitotic cell cycle; type I interferon-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; interferon-gamma-mediated signaling pathway; leukocyte migration; protein dephosphorylation; apoptotic process; positive regulation of cell proliferation; positive regulation of phosphatidylinositol 3-kinase cascade; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; cell differentiation; T cell costimulation; peptidyl-tyrosine dephosphorylation; negative regulation of peptidyl-tyrosine phosphorylation; cell proliferation; blood coagulation; G-protein coupled receptor signaling pathway | |
| RB1 | negative regulation of S phase of mitotic cell cycle; negative regulation of smoothened signaling pathway; positive regulation of macrophage differentiation; positive regulation of mitotic metaphase/anaphase transition; enucleate erythrocyte differentiation; myoblast differentiation; interspecies interaction between organisms; regulation of lipid kinase activity; negative regulation of sequence-specific DNA binding transcription factor activity; regulation of centromere complex assembly; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; digestive tract development; cell morphogenesis involved in neuron differentiation; negative regulation of epithelial cell proliferation; striated muscle cell differentiation; cell division; G1 phase; neuron apoptosis; protein localization to chromosome, centromeric region; regulation of cohesin localization to chromatin; negative regulation of transcri | |
| RELA | interspecies interaction between organisms; response to cobalamin; positive regulation of interleukin-12 biosynthetic process; innate immune response; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of insulin receptor signaling pathway; nerve growth factor receptor signaling pathway; regulation of inflammatory response; T cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; response to cAMP; defense response to virus; membrane protein intracellular domain proteolysis; cytokine-mediated signaling pathway; response to morphine; response to amino acid stimulus; positive regulation of chondrocyte differentiation; response to muramyl dipeptide; response to progesterone stimulus; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptotic process; response to hydrogen peroxide; response to drug; | |
| RIPK1 | positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; response to tumor necrosis factor; TRIF-dependent toll-like receptor signaling pathway; positive regulation of programmed cell death; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; negative regulation of extrinsic apoptotic signaling pathway; positive regulation of reactive oxygen species metabolic process; regulation of ATP:ADP antiporter activity; positive regulation of anti-apoptosis; positive regulation of necrotic cell death; protein autophosphorylation; positive regulation of NF-kappaB transcription factor activity; positive regulation of necroptosis; induction of necroptosis by extracellular signals; tumor necrosis factor-mediated signaling pathway; positive regulation of tumor necrosis factor production; positive regulation of interleukin-8 production; activation of pro-apoptotic gene products; induction of apoptosis by | |
| RNASEH2A | DNA replication; RNA catabolic process | |
| SMARCB1 | positive regulation of sequence-specific DNA binding transcription factor activity; blastocyst hatching; positive regulation of transcription from RNA polymerase II promoter; retroviral genome replication; interspecies interaction between organisms; positive regulation by host of viral transcription; cell differentiation; DNA integration; negative regulation of cell proliferation; nervous system development; cell cycle; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; nucleosome disassembly | |
| STAT1 | type I interferon-mediated signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; response to cytokine stimulus; tumor necrosis factor-mediated signaling pathway; response to lipopolysaccharide; lipopolysaccharide-mediated signaling pathway; cytokine-mediated signaling pathway; negative regulation of angiogenesis; response to bacterium; response to virus; positive regulation of transcription from RNA polymerase II promoter; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; regulation of transcription from RNA polymerase II promoter; induction of apoptosis; regulation of type I interferon-mediated signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; renal tubule development; negative regulation of metanephric nephron tubule epithelial cell differentiation; JAK-STAT cascade; blood circulation; metanephric mesenchymal cell differentiation; negative regulation of transcription from | |
| STAT3 | temperature homeostasis; response to estradiol stimulus; intracellular receptor mediated signaling pathway; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; eye photoreceptor cell differentiation; nervous system development; sexual reproduction; cytokine-mediated signaling pathway; response to organic cyclic compound; astrocyte differentiation; radial glial cell differentiation; growth hormone receptor signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; interleukin-6-mediated signaling pathway; cell proliferation; eating behavior; nerve growth factor receptor signaling pathway; interspecies interaction between organisms; response to ethanol; positive regulation of Notch signaling pathway; signal transduction; acute-phase response; response to peptide hormone stimulus; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription | |
| STAT5A | peptidyl-tyrosine phosphorylation; regulation of epithelial cell differentiation; regulation of cell adhesion; lipid storage; positive regulation of B cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of mitotic cell cycle; taurine metabolic process; cytokine-mediated signaling pathway; regulation of steroid metabolic process; valine metabolic process; positive regulation of cell proliferation; lactation; female pregnancy; JAK-STAT cascade; fatty acid metabolic process; creatine metabolic process; positive regulation of inflammatory response; development of secondary male sexual characteristics; positive regulation of gamma-delta T cell differentiation; positive regulation of survival gene product expression; Peyer's patch development; negative regulation of apoptotic process; mammary gland epithelium development; epithelial cell differentiation involved in prostate gland development; prostate gland epithelium morphogenesis; positive regulation of | |
| STAT6 | positive regulation of transcription from RNA polymerase II promoter; positive regulation of isotype switching to IgE isotypes; regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; response to cytokine stimulus; cytokine-mediated signaling pathway; signal transduction; negative regulation of type 2 immune response; negative regulation of transcription from RNA polymerase II promoter | |
| TGFB1I1 | negative regulation of cell proliferation; ubiquitin-dependent SMAD protein catabolic process; transcription from RNA polymerase II promoter; cell adhesion; positive regulation of transcription, DNA-dependent; positive regulation of epithelial to mesenchymal transition; Wnt receptor signaling pathway; cell differentiation; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; androgen receptor signaling pathway | |
| TP53 | protein complex assembly; multicellular organismal development; apoptotic process; response to DNA damage stimulus; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; ER overload response; cell cycle arrest; Ras protein signal transduction; gastrulation; regulation of transcription, DNA-dependent; double-strand break repair; nucleotide-excision repair; base-excision repair; T cell lineage commitment; B cell lineage commitment; T cell proliferation involved in immune response; somitogenesis; in utero embryonic development; response to X-ray; cellular response to drug; multicellular organism growth; cellular response to UV; cellular protein localization; T cell differentiation in thymus; positive regulation of protein oligomerization; mitotic cell cycle G1/S transition DNA damage checkpoint; positive regulation of histone deacetylation; negative regulation | |
| TRADD | apoptotic process; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; signal transduction; induction of apoptosis by extracellular signals; activation of pro-apoptotic gene products; tumor necrosis factor-mediated signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of hair follicle development; extrinsic apoptotic signaling pathway | |
| TUBB2A | microtubule-based movement; protein folding; mitosis; neuron differentiation; 'de novo' posttranslational protein folding; protein polymerization; cellular protein metabolic process | |
| TYR | visual perception; cell proliferation; pigmentation; thymus development; melanin biosynthetic process from tyrosine; eye pigment biosynthetic process | |
| VASP | actin cytoskeleton organization; actin polymerization or depolymerization; axon guidance; neural tube closure; cell junction assembly; T cell receptor signaling pathway; protein homotetramerization | |
| VIL1 | regulation of actin nucleation; actin filament severing; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to hepatocyte growth factor stimulus; positive regulation of actin filament bundle assembly; positive regulation of cell migration; actin filament depolymerization; actin filament polymerization; negative regulation of endopeptidase activity; positive regulation of epithelial cell migration; response to bacterium; regulation of cell shape; epidermal growth factor receptor signaling pathway; cytoskeleton organization; protein complex assembly; actin filament capping; cytoplasmic actin-based contraction involved in cell motility; regulation of wound healing; cellular response to epidermal growth factor stimulus; regulation of lamellipodium morphogenesis | |
| XRCC6 | negative regulation of transcription, DNA-dependent; viral reproduction; provirus integration; initiation of viral infection; V(D)J recombination; DNA repair; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neurogenesis; response to ionizing radiation; double-strand break repair via nonhomologous end joining; double-strand break repair; telomere maintenance; DNA ligation | |
| YWHAG | protein targeting; regulation of signal transduction; regulation of neuron differentiation; negative regulation of protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of synaptic plasticity | |