| Gene symbol | Annotation |
| A1CF | mRNA processing; gene expression; cytidine to uridine editing; mRNA modification; protein stabilization | |
| A2ML1 | regulation of endopeptidase activity; negative regulation of peptidase activity | |
| A4GALT | lipid biosynthetic process; plasma membrane organization; glycosphingolipid biosynthetic process | |
| A4GNT | glycoprotein biosynthetic process; carbohydrate metabolic process; protein O-linked glycosylation | |
| AAAS | transmembrane transport; carbohydrate metabolic process; nucleocytoplasmic transport; learning; hexose transport; fertilization; regulation of glucose transport; glucose transport; viral reproduction; cytokine-mediated signaling pathway; small molecule metabolic process; regulation of nucleocytoplasmic transport | |
| AACS | liver development; cellular response to cholesterol; cellular response to testosterone stimulus; cellular response to glucose stimulus; adipose tissue development; white fat cell differentiation; response to ethanol; response to starvation; response to drug; response to oleic acid; positive regulation of insulin secretion; response to purine-containing compound; response to organic nitrogen; response to nutrient; fatty acid metabolic process; lipid metabolic process | |
| AADACL2 | metabolic process | |
| AADACL3 | metabolic process | |
| AADACL4 | metabolic process | |
| AADAT | glutamate metabolic process; 2-oxoglutarate metabolic process; lysine catabolic process; tryptophan catabolic process; biosynthetic process; tryptophan catabolic process to kynurenine; cellular nitrogen compound metabolic process; small molecule metabolic process; kynurenine metabolic process | |
| AAMP | cell differentiation; smooth muscle cell migration; positive regulation of endothelial cell migration; multicellular organismal development; angiogenesis | |
| AAR2 | - | |
| AARS | tRNA modification; neuromuscular process controlling balance; skin development; negative regulation of neuron apoptosis; response to amino acid stimulus; endoplasmic reticulum unfolded protein response; cerebellar Purkinje cell layer development; gene expression; tRNA processing; protein folding; alanyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; hair follicle development | |
| AARS2 | tRNA aminoacylation for protein translation; alanyl-tRNA aminoacylation; gene expression | |
| AASDHPPT | macromolecule biosynthetic process; pantothenate metabolic process; small molecule metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process | |
| AASS | cellular nitrogen compound metabolic process; protein tetramerization; small molecule metabolic process; lysine catabolic process; L-lysine catabolic process | |
| AATF | negative regulation of superoxide anion generation; cell adhesion; negative regulation of reactive oxygen species metabolic process; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; negative regulation of amyloid precursor protein biosynthetic process; ribosome biogenesis; embryonic cleavage; response to DNA damage stimulus; anti-apoptosis; induction of apoptosis by extracellular signals; regulation of mitotic cell cycle; apoptotic process | |
| ABCA1 | negative regulation of cholesterol storage; phospholipid efflux; endosome transport; positive regulation of cAMP biosynthetic process; intracellular cholesterol transport; Cdc42 protein signal transduction; cholesterol efflux; high-density lipoprotein particle assembly; response to laminar fluid shear stress; apolipoprotein A-I-mediated signaling pathway; lipoprotein metabolic process; cholesterol homeostasis; reverse cholesterol transport; cellular lipid metabolic process; small molecule metabolic process; phospholipid translocation; interleukin-1 beta secretion; phospholipid homeostasis; response to low-density lipoprotein particle stimulus; platelet dense granule organization; cellular response to lipopolysaccharide; cellular response to retinoic acid; transport; positive regulation of cholesterol efflux; peptide secretion; protein lipidation; lipid metabolic process; anion transport; phagocytosis, engulfment; lysosome organization; G-protein coupled receptor signaling pathway; steroid metabolic process; c | |
| ABCA10 | transport | |
| ABCA12 | cellular homeostasis; transport; lipid transport | |
| ABCA2 | regulation of transcription from RNA polymerase II promoter; ATP catabolic process; lipid metabolic process; transport; regulation of intracellular cholesterol transport; response to drug; cholesterol homeostasis; response to steroid hormone stimulus | |
| ABCA3 | transport; response to drug; transmembrane transport | |
| ABCA4 | visual perception; phospholipid transfer to membrane; transport; phototransduction, visible light; photoreceptor cell maintenance; response to stimulus; transmembrane transport | |
| ABCA5 | reverse cholesterol transport; transport; high-density lipoprotein particle remodeling; negative regulation of macrophage derived foam cell differentiation; cholesterol efflux | |
| ABCA6 | transport | |
| ABCA7 | phagocytosis; phospholipid efflux; transmembrane transport | |
| ABCA8 | transport; transmembrane transport | |
| ABCA9 | transport | |
| ABCB1 | stem cell proliferation; G2/M transition of mitotic cell cycle; transport; response to drug; transmembrane transport | |
| ABCB10 | transmembrane transport; transport | |
| ABCB4 | response to drug; cellular lipid metabolic process; transport; lipid metabolic process; small molecule metabolic process; response to glucocorticoid stimulus; transmembrane transport | |
| ABCB5 | regulation of membrane potential; transmembrane transport | |
| ABCB6 | cellular iron ion homeostasis; heme transport; cadmium ion transmembrane transport; transmembrane transport; transport; detoxification of cadmium ion; porphyrin-containing compound biosynthetic process | |
| ABCC1 | ATP catabolic process; prostanoid metabolic process; transport; leukotriene biosynthetic process; response to drug; small molecule metabolic process; transmembrane transport | |
| ABCC10 | transmembrane transport | |
| ABCC11 | transmembrane transport | |
| ABCC12 | transmembrane transport | |
| ABCC2 | transport; transmembrane transport; organic anion transport | |
| ABCC3 | transport; transmembrane transport; small molecule metabolic process; bile acid and bile salt transport; bile acid metabolic process; organic anion transport | |
| ABCC4 | transmembrane transport; platelet degranulation; ion transport; blood coagulation; platelet activation | |
| ABCC6 | transmembrane transport; response to stimulus; response to drug; visual perception; transport | |
| ABCC8 | potassium ion transport; synaptic transmission; response to pH; response to zinc ion; response to lipopolysaccharide; response to insulin stimulus; response to drug; positive regulation of potassium ion transport; carbohydrate metabolic process; energy reserve metabolic process; small molecule metabolic process; potassium ion transmembrane transport; transmembrane transport; regulation of insulin secretion; negative regulation of insulin secretion | |
| ABCC9 | potassium ion import; transmembrane transport; defense response to virus; synaptic transmission; potassium ion transport | |
| ABCD1 | transmembrane transport; small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; ATP catabolic process; peroxisome organization; peroxisomal membrane transport; peroxisomal long-chain fatty acid import | |
| ABCD2 | transmembrane transport; very long-chain fatty acid metabolic process; positive regulation of fatty acid beta-oxidation | |
| ABCD3 | transmembrane transport; response to drug; ATP catabolic process | |
| ABCD4 | transmembrane transport | |
| ABCG1 | regulation of transcription, DNA-dependent; reverse cholesterol transport; amyloid precursor protein catabolic process; cholesterol homeostasis; positive regulation of cholesterol biosynthetic process; lipoprotein metabolic process; response to high density lipoprotein particle stimulus; phospholipid homeostasis; detection of hormone stimulus; cholesterol metabolic process; lipid metabolic process; transmembrane transport; small molecule metabolic process; glycoprotein transport; regulation of cholesterol esterification; high-density lipoprotein particle remodeling; low-density lipoprotein particle remodeling; response to lipid; phospholipid efflux; positive regulation of cholesterol efflux; cholesterol efflux; response to organic substance; negative regulation of macrophage derived foam cell differentiation; intracellular cholesterol transport; phospholipid transport; negative regulation of cholesterol storage | |
| ABCG2 | urate metabolic process; heme transport; cellular iron ion homeostasis; transport; transmembrane transport; response to drug | |
| ABCG4 | cholesterol efflux; transmembrane transport | |
| ABCG5 | response to ionizing radiation; cholesterol efflux; intestinal cholesterol absorption; response to drug; cholesterol homeostasis; small molecule metabolic process; sterol transport; negative regulation of intestinal phytosterol absorption; excretion; response to nutrient; negative regulation of intestinal cholesterol absorption; transmembrane transport; lipid metabolic process; ATP catabolic process | |
| ABCG8 | small molecule metabolic process; cholesterol homeostasis; phospholipid transport; negative regulation of intestinal phytosterol absorption; excretion; lipid metabolic process; ATP catabolic process; sterol transport; intestinal cholesterol absorption; cholesterol efflux; negative regulation of intestinal cholesterol absorption; transmembrane transport | |
| ABHD1 | - | |
| ABHD12 | - | |
| ABHD12B | - | |
| ABHD14A | - | |
| ABHD15 | - | |
| ABHD16B | - | |
| ABHD2 | response to wounding; negative regulation of cell migration | |
| ABHD6 | regulation of endocannabinoid signaling pathway; long term synaptic depression; negative regulation of cell migration | |
| ABHD8 | - | |
| ABI1 | peptidyl-tyrosine phosphorylation; actin polymerization or depolymerization; somitogenesis; cellular component movement; transmembrane receptor protein tyrosine kinase signaling pathway; negative regulation of cell proliferation | |
| ABI2 | peptidyl-tyrosine phosphorylation; cell migration; actin polymerization or depolymerization; cytoskeleton organization; cellular component movement | |
| ABL1 | DNA damage response, signal transduction resulting in induction of apoptosis; axon guidance; DNA damage induced protein phosphorylation; protein modification process; regulation of transcription, DNA-dependent; mismatch repair; regulation of transcription involved in S phase of mitotic cell cycle; blood coagulation; regulation of response to DNA damage stimulus; regulation of actin cytoskeleton reorganization; regulation of cell motility; negative regulation of protein serine/threonine kinase activity; positive regulation of oxidoreductase activity; positive regulation of muscle cell differentiation; positive regulation of apoptotic process; signal transduction in response to DNA damage; muscle cell differentiation; regulation of cell adhesion; regulation of endocytosis; actin cytoskeleton organization; peptidyl-tyrosine phosphorylation; regulation of autophagy | |
| ABL2 | axon guidance; regulation of actin cytoskeleton reorganization; regulation of cell motility; cellular response to retinoic acid; positive regulation of oxidoreductase activity; regulation of cell adhesion; regulation of endocytosis; peptidyl-tyrosine phosphorylation; positive regulation of neuron projection development; regulation of autophagy; signal transduction; protein phosphorylation; protein modification process | |
| ABLIM1 | positive regulation of transcription from RNA polymerase II promoter; cytoskeleton organization; organ morphogenesis; visual perception; axon guidance | |
| ABLIM3 | positive regulation of transcription from RNA polymerase II promoter; axon guidance; cytoskeleton organization | |
| ABRA | positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of Rho protein signal transduction; protein transport; protein import into nucleus, translocation | |
| ABRACL | - | |
| ABTB1 | - | |
| ABTB2 | regulation of cell growth | |
| ACAA2 | acetyl-CoA metabolic process; anti-apoptosis; cholesterol biosynthetic process; fatty acid beta-oxidation; fatty acid metabolic process; lipid metabolic process | |
| ACACA | lipid homeostasis; tissue homeostasis; acetyl-CoA metabolic process; energy reserve metabolic process; fatty acid biosynthetic process; response to organic cyclic compound; triglyceride biosynthetic process; positive regulation of cellular metabolic process; long-chain fatty-acyl-CoA biosynthetic process; protein homotetramerization; small molecule metabolic process; multicellular organismal protein metabolic process; cellular lipid metabolic process; response to drug | |
| ACACB | fatty acid biosynthetic process; acetyl-CoA metabolic process; protein homotetramerization; regulation of fatty acid oxidation; small molecule metabolic process; cellular lipid metabolic process; positive regulation of cellular metabolic process; carnitine shuttle; energy reserve metabolic process | |
| ACAD10 | - | |
| ACAD11 | fatty acid beta-oxidation using acyl-CoA dehydrogenase | |
| ACAD8 | small molecule metabolic process; cellular nitrogen compound metabolic process; branched chain family amino acid catabolic process; lipid metabolic process; regulation of transcription, DNA-dependent | |
| ACADL | small molecule metabolic process; oxidation-reduction process; regulation of cholesterol metabolic process; protein homotetramerization; negative regulation of fatty acid oxidation; negative regulation of fatty acid biosynthetic process; cellular lipid metabolic process; cellular lipid catabolic process; long-chain fatty acid catabolic process; carnitine catabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; fatty acid metabolic process; temperature homeostasis | |
| ACADM | carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA dehydrogenase; cellular lipid metabolic process; small molecule metabolic process; carnitine biosynthetic process; medium-chain fatty acid metabolic process; medium-chain fatty acid catabolic process; oxidation-reduction process | |
| ACADS | small molecule metabolic process; butyrate catabolic process; cellular lipid metabolic process; protein homotetramerization; response to starvation; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation; fatty acid metabolic process; response to glucocorticoid stimulus | |
| ACADSB | small molecule metabolic process; cellular nitrogen compound metabolic process; branched chain family amino acid catabolic process; acyl-CoA metabolic process; fatty acid metabolic process; lipid metabolic process | |
| ACADVL | negative regulation of fatty acid oxidation; regulation of cholesterol metabolic process; negative regulation of fatty acid biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; very long-chain fatty acid catabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; endoplasmic reticulum unfolded protein response; energy derivation by oxidation of organic compounds; activation of signaling protein activity involved in unfolded protein response; fatty acid beta-oxidation; fatty acid metabolic process; temperature homeostasis | |
| ACAP1 | lipid metabolic process; intracellular signal transduction; regulation of ARF GTPase activity; protein transport | |
| ACAP3 | filopodium assembly; regulation of ARF GTPase activity; signal transduction | |
| ACAT2 | lipid metabolic process | |
| ACBD4 | - | |
| ACBD5 | transport | |
| ACBD6 | - | |
| ACCS | biosynthetic process | |
| ACE | regulation of systemic arterial blood pressure by renin-angiotensin; proteolysis; sensory perception of pain; regulation of vasodilation; neutrophil mediated immunity; regulation of renal output by angiotensin; angiotensin catabolic process in blood; blood vessel remodeling; kidney development; response to hypoxia; mononuclear cell proliferation; hormone catabolic process; regulation of smooth muscle cell migration; response to nutrient levels; response to lipopolysaccharide; regulation of blood pressure; hemopoietic stem cell differentiation; heart contraction; positive regulation of neurogenesis; positive regulation of inflammatory response; arachidonic acid secretion; regulation of vasoconstriction; peptide catabolic process; positive regulation of apoptotic process; eating behavior | |
| ACE2 | proteolysis; regulation of systemic arterial blood pressure by renin-angiotensin; angiotensin-mediated drinking behavior; regulation of cytokine production; response to virus; regulation of vasoconstriction; receptor biosynthetic process; regulation of cell proliferation; regulation of vasodilation; angiotensin catabolic process in blood; interspecies interaction between organisms; entry of virus into host cell; virion attachment, binding of host cell surface receptor; regulation of inflammatory response; positive regulation of reactive oxygen species metabolic process | |
| ACER1 | small molecule metabolic process; sphingolipid biosynthetic process; regulation of lipid metabolic process; sphingolipid metabolic process; ceramide catabolic process | |
| ACER2 | negative regulation of protein glycosylation in Golgi; sphingosine biosynthetic process; small molecule metabolic process; negative regulation of cell adhesion mediated by integrin; response to retinoic acid; sphingolipid biosynthetic process; positive regulation of cell proliferation; ceramide metabolic process; sphingolipid metabolic process; lipid metabolic process; negative regulation of cell-matrix adhesion | |
| ACIN1 | erythrocyte differentiation; ATP catabolic process; apoptotic process; apoptotic chromosome condensation; cellular component disassembly involved in apoptosis; positive regulation of monocyte differentiation | |
| ACKR2 | - | |
| ACLY | energy reserve metabolic process; ATP catabolic process; lipid biosynthetic process; positive regulation of cellular metabolic process; triglyceride biosynthetic process; coenzyme A metabolic process; citrate metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; cellular carbohydrate metabolic process; small molecule metabolic process | |
| ACMSD | small molecule metabolic process; cellular nitrogen compound metabolic process; tryptophan catabolic process; quinolinate metabolic process | |
| ACO1 | regulation of translation; intestinal absorption; regulation of gene expression; response to iron(II) ion; post-embryonic development; metabolic process; cellular iron ion homeostasis; citrate metabolic process; tricarboxylic acid cycle | |
| ACO2 | generation of precursor metabolites and energy; small molecule metabolic process; isocitrate metabolic process; citrate metabolic process; tricarboxylic acid cycle | |
| ACOT11 | fatty acid metabolic process; response to temperature stimulus; response to cold; intracellular signal transduction | |
| ACOT12 | acetyl-CoA metabolic process; lipid metabolic process; fatty acid metabolic process; acyl-CoA metabolic process | |
| ACOT13 | protein homotetramerization | |
| ACOT7 | lipid metabolic process | |
| ACOT9 | acyl-CoA metabolic process | |
| ACOX2 | small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; bile acid metabolic process; bile acid biosynthetic process; fatty acid metabolic process | |
| ACOX3 | fatty acid metabolic process; small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase | |
| ACP2 | skeletal system development; autophagic cell death; dephosphorylation; response to organic substance; lysosome organization | |
| ACPP | - | |
| ACPT | - | |
| ACR | response to biotic stimulus; activation of adenylate cyclase activity; penetration of zona pellucida; acrosome reaction; single fertilization; acrosome matrix dispersal; proteolysis; response to steroid hormone stimulus | |
| ACRBP | - | |
| ACRC | - | |
| ACRV1 | multicellular organismal development | |
| ACSBG1 | lipid metabolic process; myelination; response to glucocorticoid stimulus; long-chain fatty acid metabolic process; ovarian follicle atresia; very long-chain fatty acid metabolic process | |
| ACSBG2 | fatty acid metabolic process; multicellular organismal development; spermatogenesis; lipid metabolic process; cell differentiation | |
| ACSF2 | fatty acid metabolic process; lipid metabolic process | |
| ACSF3 | lipid metabolic process; fatty acid metabolic process; fatty acid biosynthetic process; malonate catabolic process | |
| ACSL1 | small molecule metabolic process; cellular lipid metabolic process; regulation of fatty acid oxidation; long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; fatty acid metabolic process | |
| ACSL4 | lipid metabolic process; positive regulation of cell growth; long-chain fatty-acyl-CoA biosynthetic process; cellular lipid metabolic process; small molecule metabolic process; embryonic process involved in female pregnancy; dendritic spine development; triglyceride biosynthetic process; response to nutrient; fatty acid metabolic process; response to interleukin-15 | |
| ACSL5 | long-chain fatty-acyl-CoA biosynthetic process; response to cholesterol; small molecule metabolic process; positive regulation of triglyceride biosynthetic process; fatty acid metabolic process; cellular lipid metabolic process; fatty acid transport; triglyceride biosynthetic process; cellular response to insulin stimulus; response to nutrient; positive regulation of plasma membrane long-chain fatty acid transport; response to glucose stimulus; response to sucrose stimulus | |
| ACSL6 | fatty acid metabolic process; acyl-CoA metabolic process; neuroblast proliferation; triglyceride biosynthetic process; long-chain fatty-acyl-CoA biosynthetic process; cellular lipid metabolic process; small molecule metabolic process | |
| ACSM3 | regulation of blood pressure; fatty acid biosynthetic process; lipid metabolic process | |
| ACSM6 | fatty acid metabolic process; lipid metabolic process | |
| ACSS1 | acetyl-CoA biosynthetic process; ethanol oxidation; propionate biosynthetic process; acetate biosynthetic process; small molecule metabolic process; xenobiotic metabolic process | |
| ACSS2 | acetyl-CoA biosynthetic process; small molecule metabolic process; lipid biosynthetic process; xenobiotic metabolic process; ethanol oxidation | |
| ACSS3 | - | |
| ACTA1 | muscle contraction; skeletal muscle fiber development; skeletal muscle thin filament assembly; response to steroid hormone stimulus; response to mechanical stimulus; response to extracellular stimulus; response to lithium ion; cell growth; muscle filament sliding; skeletal muscle fiber adaptation | |
| ACTA2 | glomerular mesangial cell development; vascular smooth muscle contraction; response to virus; regulation of blood pressure; muscle contraction | |
| ACTG2 | muscle contraction | |
| ACTL6A | chromatin remodeling; regulation of transcription from RNA polymerase II promoter; signal transduction; neural retina development; DNA repair; DNA recombination; nervous system development; regulation of growth; histone H4 acetylation; histone H2A acetylation | |
| ACTL6B | chromatin organization; nervous system development; chromatin remodeling; regulation of transcription from RNA polymerase II promoter | |
| ACTL7A | - | |
| ACTL7B | - | |
| ACTL8 | - | |
| ACTL9 | - | |
| ACTN1 | cell junction assembly; platelet degranulation; blood coagulation; platelet activation; regulation of apoptotic process; focal adhesion assembly; actin filament bundle assembly; negative regulation of cellular component movement | |
| ACTN2 | muscle filament sliding; regulation of apoptotic process; focal adhesion assembly; protein homotetramerization; platelet degranulation; cell adhesion; synaptic transmission; blood coagulation; microspike assembly; platelet activation | |
| ACTR10 | microtubule-based movement | |
| ACTR1A | mitotic cell cycle; G2/M transition of mitotic cell cycle; vesicle-mediated transport | |
| ACTR1B | - | |
| ACTR2 | cellular component movement | |
| ACTRT1 | - | |
| ACTRT2 | - | |
| ACTRT3 | - | |
| ACVR1 | positive regulation of bone mineralization; BMP signaling pathway; regulation of ossification; negative regulation of signal transduction; embryo development; heart development; mesoderm development; determination of left/right symmetry; germ cell development; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein serine/threonine kinase signaling pathway; protein phosphorylation; acute inflammatory response; neural crest cell migration; mesoderm formation; gastrulation with mouth forming second; in utero embryonic development; urogenital system development; patterning of blood vessels; G1/S transition of mitotic cell cycle; negative regulation of apoptotic process; positive regulation of osteoblast differentiation; positive regulation of transcription, DNA-dependent; regulation of skeletal muscle tissue development; smooth muscle cell differentiation; pharyngeal system development; cellular response to glucocorticoid stimulus; negative regulation of activin receptor signal | |
| ACVR1B | protein phosphorylation; protein autophosphorylation; positive regulation of erythrocyte differentiation; positive regulation of activin receptor signaling pathway; activin receptor signaling pathway; negative regulation of cell growth; peptidyl-threonine phosphorylation; transmembrane receptor protein serine/threonine kinase signaling pathway; signal transduction; induction of apoptosis; regulation of transcription, DNA-dependent; G1/S transition of mitotic cell cycle | |
| ACVR2A | mesoderm development; determination of left/right symmetry; BMP signaling pathway; positive regulation of bone mineralization; response to organic substance; anterior/posterior pattern specification; spermatogenesis; transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of protein phosphorylation; gastrulation with mouth forming second; regulation of BMP signaling pathway; activin receptor signaling pathway; Sertoli cell proliferation; regulation of nitric-oxide synthase activity; embryonic skeletal system development; positive regulation of follicle-stimulating hormone secretion; positive regulation of osteoblast differentiation; positive regulation of erythrocyte differentiation; penile erection; sperm ejaculation; positive regulation of activin receptor signaling pathway | |
| ACVR2B | insulin secretion; positive regulation of activin receptor signaling pathway; lung development; positive regulation of bone mineralization; BMP signaling pathway; pancreas development; activation of protein kinase activity; organ growth; odontogenesis of dentin-containing tooth; positive regulation of osteoblast differentiation; embryonic foregut morphogenesis; skeletal system morphogenesis; palate development; post-embryonic development; gastrulation with mouth forming second; kidney development; regulation of transcription, DNA-dependent; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; determination of left/right symmetry; anterior/posterior pattern specification; pattern specification process; mesoderm development; heart development; response to glucose stimulus | |
| ACVRL1 | wound healing, spreading of epidermal cells; positive regulation of BMP signaling pathway; negative regulation of cell migration; negative regulation of cell growth; negative regulation of endothelial cell migration; negative regulation of cell proliferation; regulation of blood pressure; blood circulation; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein serine/threonine kinase signaling pathway; signal transduction; negative regulation of cell adhesion; protein phosphorylation; regulation of transcription, DNA-dependent; regulation of DNA replication; blood vessel endothelial cell proliferation involved in sprouting angiogenesis; blood vessel maturation; positive regulation of endothelial cell proliferation; negative regulation of endothelial cell proliferation; regulation of endothelial cell proliferation; in utero embryonic development; angiogenesis; positive regulation of endothelial cell differentiation; regulation of blood vessel endothelial cell migration; neg | |
| ACY1 | metabolic process; cellular amino acid metabolic process; proteolysis | |
| ACY3 | interspecies interaction between organisms; metabolic process | |
| ADAD1 | cell differentiation; spermatid development; RNA processing; spermatogenesis; multicellular organismal development | |
| ADAD2 | RNA processing | |
| ADAL | hypoxanthine salvage; inosine biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; nucleotide metabolic process; adenosine catabolic process | |
| ADAM10 | Notch receptor processing; PMA-inducible membrane protein ectodomain proteolysis; constitutive protein ectodomain proteolysis; response to tumor necrosis factor; positive regulation of cell migration; positive regulation of cell growth; positive regulation of T cell chemotaxis; positive regulation of cell proliferation; cell-cell signaling; integrin-mediated signaling pathway; Notch signaling pathway; epidermal growth factor receptor signaling pathway; negative regulation of cell adhesion; membrane protein ectodomain proteolysis; proteolysis; monocyte activation; protein phosphorylation; in utero embryonic development | |
| ADAM11 | proteolysis; integrin-mediated signaling pathway | |
| ADAM12 | epidermal growth factor receptor signaling pathway; myoblast fusion; proteolysis; cell adhesion | |
| ADAM15 | cell adhesion; cell-matrix adhesion; collagen catabolic process; tissue regeneration; proteolysis; cardiac epithelial to mesenchymal transition; angiogenesis | |
| ADAM17 | response to hypoxia; membrane protein intracellular domain proteolysis; wound healing, spreading of epidermal cells; cell adhesion mediated by integrin; T cell differentiation in thymus; regulation of mast cell apoptosis; positive regulation of chemokine production; negative regulation of interleukin-8 production; response to lipopolysaccharide; positive regulation of cyclin-dependent protein kinase activity involved in G1/S; epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; positive regulation of transforming growth factor beta receptor signaling pathway; cell adhesion; epidermal growth factor receptor signaling pathway; Notch signaling pathway; positive regulation of cell proliferation; positive regulation of T cell chemotaxis; B cell differentiation; positive regulation of cell growth; positive regulation of leukocyte chemotaxis; PMA-inducible membrane protein ectodomain proteolysis; positive regulation of cellular component movement; positive regul | |
| ADAM18 | multicellular organismal development; proteolysis; cell differentiation; spermatogenesis | |
| ADAM19 | proteolysis | |
| ADAM2 | adult behavior; visual learning; fusion of sperm to egg plasma membrane; cell adhesion; proteolysis | |
| ADAM20 | single fertilization; proteolysis | |
| ADAM23 | central nervous system development; cell adhesion; proteolysis | |
| ADAM29 | proteolysis; spermatogenesis | |
| ADAM30 | proteolysis | |
| ADAM33 | integrin-mediated signaling pathway; proteolysis | |
| ADAM7 | proteolysis | |
| ADAMDEC1 | negative regulation of cell adhesion; proteolysis; immune response | |
| ADAMTS1 | heart trabecula formation; ovulation from ovarian follicle; kidney development; proteolysis; integrin-mediated signaling pathway; negative regulation of cell proliferation | |
| ADAMTS10 | integrin-mediated signaling pathway; proteolysis | |
| ADAMTS12 | proteolysis | |
| ADAMTS14 | collagen catabolic process; proteolysis | |
| ADAMTS15 | proteolysis | |
| ADAMTS16 | proteolysis | |
| ADAMTS17 | proteolysis | |
| ADAMTS18 | proteolysis | |
| ADAMTS19 | proteolysis | |
| ADAMTS2 | lung development; collagen catabolic process; collagen fibril organization; protein processing; metabolic process; spermatogenesis; skin development; proteolysis | |
| ADAMTS4 | skeletal system development; proteolysis | |
| ADAMTS5 | proteolysis | |
| ADAMTS6 | proteolysis | |
| ADAMTS8 | negative regulation of cell proliferation; proteolysis | |
| ADAMTS9 | proteolysis; glycoprotein catabolic process; multicellular organismal development; positive regulation of melanocyte differentiation; regulation of developmental pigmentation | |
| ADAMTSL1 | - | |
| ADAMTSL2 | negative regulation of transforming growth factor beta receptor signaling pathway | |
| ADAMTSL3 | - | |
| ADAMTSL4 | positive regulation of apoptotic process; extracellular matrix organization | |
| ADAP2 | heart development; regulation of ARF GTPase activity; positive regulation of GTPase activity | |
| ADAR | negative regulation of apoptotic process; adenosine to inosine editing; mRNA processing; gene expression; base conversion or substitution editing; mRNA modification; cytokine-mediated signaling pathway; gene silencing by RNA; type I interferon-mediated signaling pathway | |
| ADARB1 | adenosine to inosine editing; RNA processing; mRNA processing; gene expression; base conversion or substitution editing; mRNA modification | |
| ADARB2 | RNA processing; mRNA processing | |
| ADAT1 | RNA processing; tRNA processing | |
| ADCK1 | - | |
| ADCK2 | - | |
| ADCK3 | cell death | |
| ADCK4 | - | |
| ADCY1 | transmembrane transport; cAMP biosynthetic process; cellular response to glucagon stimulus; nerve growth factor receptor signaling pathway; small molecule metabolic process; response to drug; intracellular signal transduction; activation of protein kinase A activity; response to lithium ion; fibroblast growth factor receptor signaling pathway; circadian rhythm; long-term memory; axonogenesis; synaptic transmission; activation of phospholipase C activity; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; energy reserve metabolic process | |
| ADCY2 | activation of protein kinase A activity; energy reserve metabolic process; cellular response to glucagon stimulus; transmembrane transport; nerve growth factor receptor signaling pathway; small molecule metabolic process; intracellular signal transduction; fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of phospholipase C activity; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; inhibition of adenylate cyclase activity by G-protein signaling pathway | |
| ADCY3 | fibroblast growth factor receptor signaling pathway; sensory perception of smell; synaptic transmission; activation of phospholipase C activity; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; female meiosis; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; small molecule metabolic process; intracellular signal transduction; nerve growth factor receptor signaling pathway; response to stimulus; transmembrane transport; cellular response to glucagon stimulus; activation of protein kinase A activity | |
| ADCY4 | water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; signal transduction; epidermal growth factor receptor signaling pathway; activation of phospholipase C activity; small molecule metabolic process; intracellular signal transduction; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; inhibition of adenylate cyclase activity by G-protein signaling pathway; cellular response to glucagon stimulus; transmembrane transport; nerve growth factor receptor signaling pathway | |
| ADCY5 | activation of adenylate cyclase activity by G-protein signaling pathway; energy reserve metabolic process; cAMP biosynthetic process; GTP catabolic process; water transport; signal transduction; epidermal growth factor receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of phospholipase C activity; fibroblast growth factor receptor signaling pathway; activation of protein kinase A activity; intracellular signal transduction; small molecule metabolic process; nerve growth factor receptor signaling pathway; transmembrane transport; cellular response to glucagon stimulus; synaptic transmission | |
| ADCY6 | fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of phospholipase C activity; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; activation of protein kinase A activity; epidermal growth factor receptor signaling pathway; signal transduction; water transport; intracellular signal transduction; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; small molecule metabolic process; nerve growth factor receptor signaling pathway; transmembrane transport; cellular response to glucagon stimulus | |
| ADCY7 | positive regulation of cAMP biosynthetic process; cellular response to glucagon stimulus; cellular response to ethanol; transmembrane transport; nerve growth factor receptor signaling pathway; small molecule metabolic process; intracellular signal transduction; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; synaptic transmission; inhibition of adenylate cyclase activity by G-protein signaling pathway; energy reserve metabolic process; cAMP biosynthetic process; GTP catabolic process; water transport; signal transduction; epidermal growth factor receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; activation of phospholipase C activity | |
| ADCY8 | signal transduction; cellular response to glucagon stimulus; transmembrane transport; nerve growth factor receptor signaling pathway; small molecule metabolic process; intracellular signal transduction; activation of protein kinase A activity; cAMP-mediated signaling; fibroblast growth factor receptor signaling pathway; learning or memory; activation of phospholipase C activity; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; synaptic transmission; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process | |
| ADCY9 | small molecule metabolic process; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of phospholipase C activity; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; intracellular signal transduction; nerve growth factor receptor signaling pathway; cellular response to glucagon stimulus; transmembrane transport | |
| ADCYAP1 | nerve growth factor receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; female pregnancy; cell-cell signaling; activation of adenylate cyclase activity; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; negative regulation of cell cycle | |
| ADCYAP1R1 | cell surface receptor signaling pathway; positive regulation of inositol phosphate biosynthetic process; negative regulation of cell death; nerve growth factor receptor signaling pathway; development of primary female sexual characteristics; response to ethanol; response to drug; multicellular organismal response to stress; response to estradiol stimulus; positive regulation of cAMP biosynthetic process; cell differentiation; cAMP-mediated signaling; positive regulation of calcium ion transport into cytosol; spermatogenesis; multicellular organismal development; activation of phospholipase C activity; activation of adenylate cyclase activity; transmembrane receptor protein tyrosine kinase signaling pathway | |
| ADD1 | actin cytoskeleton organization; endoplasmic reticulum unfolded protein response; positive regulation of protein binding; barbed-end actin filament capping; actin filament bundle assembly; apoptotic process; cellular component disassembly involved in apoptosis; activation of signaling protein activity involved in unfolded protein response | |
| ADD2 | barbed-end actin filament capping; positive regulation of protein binding; hemopoiesis; actin cytoskeleton organization; ion transport; actin filament bundle assembly | |
| ADD3 | response to drug | |
| ADGRA2 | regulation of chemotaxis; sprouting angiogenesis; G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; central nervous system development; endothelial cell migration; regulation of angiogenesis | |
| ADGRA3 | neuropeptide signaling pathway; G-protein coupled receptor signaling pathway | |
| ADGRB2 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; negative regulation of angiogenesis | |
| ADGRB3 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; negative regulation of angiogenesis | |
| ADGRD1 | neuropeptide signaling pathway; G-protein coupled receptor signaling pathway | |
| ADGRE1 | neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; cell adhesion | |
| ADGRE5 | cell-cell signaling; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; cell surface receptor signaling pathway; cell adhesion; immune response; inflammatory response; cellular component movement | |
| ADGRF1 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADGRF2 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADGRF4 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADGRG1 | neuropeptide signaling pathway; cell-cell signaling; brain development; G-protein coupled receptor signaling pathway; cell adhesion | |
| ADGRG2 | spermatogenesis; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway | |
| ADGRG3 | neuropeptide signaling pathway | |
| ADGRG4 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADGRG5 | neuropeptide signaling pathway; G-protein coupled receptor signaling pathway | |
| ADGRG7 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADGRL1 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; brain development | |
| ADGRL2 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADGRL4 | G-protein coupled receptor signaling pathway; neuropeptide signaling pathway | |
| ADH6 | response to ethanol; small molecule metabolic process; xenobiotic metabolic process; ethanol oxidation | |
| ADH7 | retinoid metabolic process; ethanol oxidation; xenobiotic metabolic process; response to bacterium; negative regulation of signal transduction; fatty acid omega-oxidation; small molecule metabolic process; response to ethanol; oxidation-reduction process | |
| ADIPOR2 | fatty acid oxidation; hormone-mediated signaling pathway; lipid metabolic process | |
| ADNP | response to inorganic substance; positive regulation of synapse assembly; response to carbohydrate stimulus; short-term memory; negative regulation of gene expression; regulation of protein ADP-ribosylation; positive regulation of neuron projection development; positive regulation of cGMP biosynthetic process; nitric oxide homeostasis; negative regulation of synaptic transmission; negative regulation of neuron apoptosis; cellular response to extracellular stimulus; positive regulation of axon extension; estrous cycle phase; negative regulation of protein binding; activation of protein kinase activity; neuroprotection; positive regulation of peptidyl-tyrosine phosphorylation | |
| ADNP2 | positive regulation of cell growth; cellular response to oxidative stress; negative regulation of cell death; cellular response to retinoic acid; neuron differentiation | |
| ADORA1 | negative regulation of acute inflammatory response; induction of apoptosis by extracellular signals; negative regulation of neurotrophin production; positive regulation of protein dephosphorylation; negative regulation of renal sodium excretion; negative regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of apoptotic process; positive regulation of potassium ion transport; positive regulation of epidermal growth factor-activated receptor activity; negative regulation of blood pressure; positive regulation of blood pressure; negative regulation of heart contraction; negative regulation of vasodilation; negative regulation of hormone secretion; regulation of synaptic plasticity; cognition; regulation of respiratory gaseous exchange by neurological system process; response to hypoxia; temperature homeostasis; activation of MAPKK activity; negative regulation of lipid catabolic process; negative regulation of cell proliferation; negative regulation of glutamate secretion; negative regula | |
| ADPGK | glycolysis; carbohydrate metabolic process | |
| ADPRHL2 | - | |
| ADPRM | - | |
| ADRA1A | activation of phospholipase C activity; apoptotic process; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; intracellular protein kinase cascade; cell-cell signaling; aging; negative regulation of cell proliferation; response to hormone stimulus; negative regulation of synaptic transmission, GABAergic; negative regulation of Rho protein signal transduction; response to drug; positive regulation of action potential; positive regulation of vasoconstriction; calcium ion transport into cytosol; positive regulation of ERK1 and ERK2 cascade; smooth muscle contraction; response to stress; signal transduction; positive regulation of protein kinase C signaling cascade; positive regulation of cardiac muscle contraction | |
| ADRA1B | cell proliferation; G-protein coupled receptor signaling pathway; locomotory behavior; adult heart development; multicellular organismal development; cell-cell signaling; intracellular protein kinase cascade; G-protein signaling, coupled to cAMP nucleotide second messenger; cell growth; visual learning; blood vessel remodeling; response to amphetamine; vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure; positive regulation of heart rate by epinephrine-norepinephrine; positive regulation of the force of heart contraction by epinephrine-norepinephrine; organ growth; glucose homeostasis; response to morphine; negative regulation of glycogen catabolic process; positive regulation of glycogen catabolic process; behavioral response to cocaine | |
| ADRA2A | intestinal absorption; epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; glucose homeostasis; fear response; positive regulation of potassium ion transport; positive regulation of MAP kinase activity; small molecule metabolic process; positive regulation of epidermal growth factor-activated receptor activity; negative regulation of calcium ion-dependent exocytosis; negative regulation of insulin secretion; regulation of insulin secretion; negative regulation of lipid catabolic process; positive regulation of membrane protein ectodomain proteolysis; activation of MAPK activity by adrenergic receptor signaling pathway; activation of phospholipase C activity by adrenergic receptor signaling pathway; inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway; negative regulation of adrenergic receptor signaling pathway; positive regulation of wound healing; negative regulation of insulin secretion involved in cellular response to glu | |
| ADRB1 | Rho protein signal transduction; positive regulation of heart rate by epinephrine-norepinephrine; diet induced thermogenesis; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; positive regulation of the force of heart contraction by norepinephrine; glycogen catabolic process; positive regulation of cell growth involved in cardiac muscle cell development; regulation of inhibitory postsynaptic membrane potential; positive regulation of calcium ion transport via voltage-gated calcium channel activity; brown fat cell differentiation; positive regulation of saliva secretion; negative regulation of smooth muscle contraction; fear response; wound healing; negative regulation of multicellular organism growth; negative regulation of urine volume; heat generation; positive regulation of cAMP biosynthetic process; sensory perception of pain; response to cold; memory; aging; activation of adenylate cyclase activity; activation of adenylate cyclase activity by G-protein | |
| ADRB3 | G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; receptor-mediated endocytosis; energy reserve metabolic process; generation of precursor metabolites and energy; carbohydrate metabolic process; desensitization of G-protein coupled receptor protein signaling pathway by arrestin; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; diet induced thermogenesis; activation of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity; aging; response to cold; heat generation; negative regulation of multicellular organism growth; eating behavior; positive regulation of MAPK cascade; brown fat cell differentiation | |
| ADRBK1 | response to organic cyclic compound; peptidyl-threonine phosphorylation; nerve growth factor receptor signaling pathway; cardiac muscle contraction; negative regulation of striated muscle contraction; follicle-stimulating hormone signaling pathway; regulation of the force of heart contraction; response to hydrogen peroxide; termination of G-protein coupled receptor signaling pathway; positive regulation of catecholamine secretion; receptor internalization; peptidyl-serine phosphorylation; fibroblast growth factor receptor signaling pathway; aging; heart development; tachykinin receptor signaling pathway; G-protein coupled acetylcholine receptor signaling pathway; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; response to oxidative stress; negative regulation of the force of heart contraction by chemical signal; desensitization of G-protein coupled receptor protein signaling pathway | |
| ADRBK2 | termination of G-protein coupled receptor signaling pathway; receptor internalization; signal transduction; protein phosphorylation | |
| ADRM1 | proteasome assembly; positive regulation of endopeptidase activity; transcription elongation from RNA polymerase II promoter | |
| ADSL | purine nucleotide biosynthetic process; response to hypoxia; purine base metabolic process; AMP biosynthetic process; response to nutrient; aerobic respiration; purine ribonucleoside monophosphate biosynthetic process; small molecule metabolic process; protein tetramerization; nucleobase-containing small molecule metabolic process | |
| ADTRP | - | |
| AEBP1 | muscle organ development; cell adhesion; proteolysis; regulation of transcription, DNA-dependent; skeletal system development | |
| AEN | response to DNA damage stimulus; apoptotic process; response to ionizing radiation; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis | |
| AFAP1 | - | |
| AFAP1L1 | - | |
| AFAP1L2 | positive regulation of interleukin-8 production; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of protein tyrosine kinase activity; regulation of interleukin-6 production; regulation of mitotic cell cycle; inflammatory response | |
| AFF1 | regulation of transcription, DNA-dependent | |
| AFF2 | mRNA processing; brain development; learning or memory; regulation of RNA splicing | |
| AFF3 | regulation of transcription, DNA-dependent; response to tumor necrosis factor; embryonic hindlimb morphogenesis | |
| AFF4 | regulation of transcription, DNA-dependent; spermatid development; transcription from RNA polymerase II promoter | |
| AFM | vitamin transport | |
| AFMID | small molecule metabolic process; tryptophan catabolic process; cellular nitrogen compound metabolic process; tryptophan catabolic process to kynurenine | |
| AFP | ovulation from ovarian follicle; liver development; transport; response to organic substance; sexual reproduction; SMAD protein signal transduction; pancreas development; organ regeneration; progesterone metabolic process | |
| AFTPH | protein transport | |
| AGAP2 | axon guidance; small GTPase mediated signal transduction; regulation of ARF GTPase activity; negative regulation of protein catabolic process; negative regulation of neuron apoptosis; protein transport | |
| AGAP3 | regulation of ARF GTPase activity; signal transduction; small GTPase mediated signal transduction | |
| AGBL2 | proteolysis | |
| AGBL5 | proteolysis; protein branching point deglutamylation; protein deglutamylation | |
| AGFG1 | regulation of ARF GTPase activity; spermatogenesis; multicellular organismal development; transport; mRNA export from nucleus; cell differentiation | |
| AGGF1 | RNA processing; positive regulation of endothelial cell proliferation; vasculogenesis; positive regulation of angiogenesis; multicellular organismal development; cell adhesion | |
| AGK | ceramide biosynthetic process; metabolic process; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway | |
| AGL | glucose metabolic process; glycogen biosynthetic process; carbohydrate metabolic process; glycogen catabolic process; response to nutrient; response to hormone stimulus; small molecule metabolic process; response to glucocorticoid stimulus | |
| AGMAT | small molecule metabolic process; cellular nitrogen compound metabolic process; putrescine biosynthetic process; spermidine biosynthetic process; agmatine biosynthetic process; polyamine metabolic process | |
| AGMO | membrane lipid metabolic process; fatty acid biosynthetic process; ether lipid metabolic process | |
| AGO2 | - | |
| AGO4 | - | |
| AGPAT3 | metabolic process; phospholipid biosynthetic process | |
| AGR3 | - | |
| AGRN | plasma membrane organization; clustering of voltage-gated sodium channels; positive regulation of neuron apoptosis; receptor clustering; multicellular organismal development; signal transduction; axon guidance; G-protein coupled acetylcholine receptor signaling pathway; synapse organization; neurotransmitter receptor metabolic process; synapse assembly; neuromuscular junction development; positive regulation of transcription from RNA polymerase II promoter; regulation of synaptic growth at neuromuscular junction; regulation of receptor activity; cell differentiation | |
| AGRP | neuropeptide signaling pathway; feeding behavior; adult feeding behavior; hormone-mediated signaling pathway; regulation of feeding behavior | |
| AGT | positive regulation of transcription, DNA-dependent; low-density lipoprotein particle remodeling; positive regulation of blood pressure; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of fatty acid biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; negative regulation of neuron apoptosis; positive regulation of MAPK cascade; positive regulation of catalytic activity; positive regulation of apoptotic process; hormone metabolic process; vasodilation; regulation of cell proliferation; positive regulation of multicellular organism growth; positive regulation of renal sodium excretion; regulation of renal sodium excretion; catenin import into nucleus; positive regulation of NAD(P)H oxidase activity; smooth muscle cell differentiation; positive regulation of reactive oxygen species metabolic process; positive regulation of branching involved in ureteric bud morphogenesis; cellular response to mechanical stimulus; ERK1 and ERK2 ca | |
| AGTPBP1 | neuromuscular process; cerebellar Purkinje cell layer development; mitochondrion organization; proteolysis; eye photoreceptor cell differentiation; cerebellar Purkinje cell differentiation; olfactory bulb development; C-terminal protein deglutamylation; protein side chain deglutamylation; neurotransmitter metabolic process; retina development in camera-type eye | |
| AGTR1 | positive regulation of reactive oxygen species metabolic process; cell chemotaxis; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; positive regulation of inflammatory response; regulation of inflammatory response; regulation of vasodilation; regulation of cell proliferation; low-density lipoprotein particle remodeling; regulation of renal sodium excretion; positive regulation of macrophage derived foam cell differentiation; Rho protein signal transduction; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; G-protein coupled receptor signaling pathway; regulation of systemic arterial blood pressure by renin-angiotensin; regulation of blood vessel size by renin-angiotensin; renin-angiotensin regulation of aldosterone production; kidney development; regulation of cell growth; positive regulation of cholesterol esterificati | |
| AGXT | glyoxylate metabolic process; response to cAMP; response to glucocorticoid stimulus; oxalic acid secretion; small molecule metabolic process; pyruvate biosynthetic process; L-alanine catabolic process; cellular nitrogen compound metabolic process; glycine biosynthetic process, by transamination of glyoxylate; glyoxylate catabolic process; protein targeting to peroxisome | |
| AGXT2 | pyrimidine base metabolic process; pyrimidine nucleoside catabolic process; glyoxylate metabolic process; nucleobase-containing small molecule metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process | |
| AHCTF1 | M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cytokinesis; protein transport; mRNA transport; nuclear pore complex assembly | |
| AHCY | sulfur amino acid metabolic process; xenobiotic metabolic process; methylation; cellular nitrogen compound metabolic process; small molecule metabolic process; one-carbon metabolic process | |
| AHCYL1 | regulation of anion transport; regulation of ion transmembrane transporter activity; regulation of mRNA 3'-end processing; positive regulation of sodium ion transport; one-carbon metabolic process; protein export from nucleus; mRNA polyadenylation | |
| AHCYL2 | one-carbon metabolic process | |
| AHDC1 | - | |
| AHNAK | nervous system development | |
| AHR | prostate gland development; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; xenobiotic metabolic process; apoptotic process; response to stress; cell cycle; response to xenobiotic stimulus; regulation of gene expression; response to organic cyclic compound; intracellular receptor mediated signaling pathway; circumferential growth involved in left ventricle morphogenesis; regulation of B cell proliferation; response to estradiol stimulus; embryonic hemopoiesis; post-embryonic hemopoiesis; positive regulation of growth rate; camera-type eye development; T cell homeostasis; positive regulation of cell size; positive regulation of transcription, DNA-dependent; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; negative regulation of systemic arterial blood pressure; glomerulus morphogenesis; cellular response to glucocorticoid stimulus; common bile duct development; kidney | |
| AHRR | regulation of transcription, DNA-dependent | |
| AHSA1 | positive regulation of ATPase activity; response to stress; protein folding | |
| AHSA2 | response to stress | |
| AHSP | protein stabilization; hemopoiesis; hemoglobin metabolic process; protein folding | |
| AIFM1 | neuron apoptosis; cell redox homeostasis; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptosis in response to endoplasmic reticulum stress; DNA fragmentation involved in apoptotic nuclear change | |
| AIFM2 | induction of apoptosis; apoptotic mitochondrial changes; chromosome condensation | |
| AIG1 | - | |
| AIM1 | - | |
| AIM1L | - | |
| AIP | xenobiotic metabolic process; protein targeting to mitochondrion; negative regulation of cyclic-nucleotide phosphodiesterase activity; protein maturation by protein folding; regulation of protein kinase A signaling cascade; signal transduction | |
| AIPL1 | retina homeostasis; response to stimulus; negative regulation of apoptotic process; regulation of cGMP metabolic process; protein farnesylation; phototransduction, visible light; visual perception; protein folding | |
| AIRE | regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; humoral immune response; immune response | |
| AJUBA | glycerophospholipid biosynthetic process; focal adhesion assembly; positive regulation of MAP kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of GTPase activity; wound healing, spreading of epidermal cells; gene silencing by miRNA; cellular protein localization; negative regulation of kinase activity; negative regulation of transcription from RNA polymerase II promoter; cell cycle; cell adhesion; calcium-dependent cell-cell adhesion; lamellipodium assembly; regulation of cell migration; positive regulation of cellular biosynthetic process; positive regulation of kinase activity; positive regulation of protein complex assembly | |
| AK5 | ADP biosynthetic process; dADP biosynthetic process; signal transduction; nucleotide biosynthetic process; pyrimidine ribonucleotide biosynthetic process; nucleobase-containing small molecule interconversion; nucleobase-containing small molecule metabolic process; ATP metabolic process; small molecule metabolic process | |
| AK7 | cell projection organization; nucleobase-containing compound metabolic process | |
| AK9 | - | |
| AKAP1 | blood coagulation; negative regulation of cardiac muscle hypertrophy; cellular response to insulin stimulus; negative regulation of protein dephosphorylation; negative regulation of NFAT protein import into nucleus; cellular response to chemical stimulus | |
| AKAP10 | signal transduction; termination of G-protein coupled receptor signaling pathway; protein localization; blood coagulation | |
| AKAP11 | regulation of protein kinase A signaling cascade; intracellular protein kinase cascade | |
| AKAP12 | positive regulation of cAMP biosynthetic process; protein targeting; signal transduction; G-protein coupled receptor signaling pathway; positive regulation of protein kinase A signaling cascade | |
| AKAP13 | regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; small GTPase mediated signal transduction; apoptotic process | |
| AKAP3 | cellular component movement; transmembrane receptor protein serine/threonine kinase signaling pathway; single fertilization; acrosome reaction; protein localization | |
| AKAP4 | single fertilization; cellular component movement; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; sperm motility; cell projection organization; protein localization | |
| AKAP5 | regulation of insulin secretion; energy reserve metabolic process; protein targeting; signal transduction; synaptic transmission; positive regulation of protein kinase A signaling cascade; positive regulation of cAMP biosynthetic process; small molecule metabolic process | |
| AKAP6 | positive regulation of protein phosphatase type 2B activity; regulation of protein kinase A signaling cascade; protein targeting | |
| AKAP7 | RNA metabolic process; regulation of protein kinase A signaling cascade; ion transport; protein localization; intracellular signal transduction | |
| AKAP8 | signal transduction; mitotic chromosome condensation; mitosis | |
| AKAP9 | G2/M transition of mitotic cell cycle; mitotic cell cycle; transport; signal transduction; synaptic transmission | |
| AKNA | regulation of transcription, DNA-dependent | |
| AKNAD1 | - | |
| AKR1A1 | aldehyde catabolic process; glucose metabolic process; cellular aldehyde metabolic process; D-glucuronate catabolic process; L-ascorbic acid biosynthetic process | |
| AKR1D1 | androgen metabolic process; bile acid biosynthetic process; bile acid catabolic process; small molecule metabolic process; cholesterol catabolic process; digestion; oxidation-reduction process; bile acid metabolic process; C21-steroid hormone metabolic process | |
| AKT3 | signal transduction; protein phosphorylation; mitochondrial genome maintenance | |
| AKTIP | protein transport; endosome to lysosome transport; early endosome to late endosome transport; positive regulation of protein binding; lysosome organization; endosome organization; apoptotic process; positive regulation of protein phosphorylation | |
| ALAD | protein homooligomerization; small molecule metabolic process; heme biosynthetic process; porphyrin-containing compound metabolic process | |
| ALAS1 | tetrapyrrole biosynthetic process; porphyrin-containing compound metabolic process; heme biosynthetic process; biosynthetic process; cellular lipid metabolic process; small molecule metabolic process | |
| ALAS2 | oxygen homeostasis; response to hypoxia; porphyrin-containing compound metabolic process; heme biosynthetic process; cellular iron ion homeostasis; biosynthetic process; erythrocyte differentiation; tetrapyrrole biosynthetic process; hemoglobin biosynthetic process; small molecule metabolic process | |
| ALB | small molecule metabolic process; platelet degranulation; lipid metabolic process; transport; response to stress; response to nutrient; sodium-independent organic anion transport; blood coagulation; bile acid metabolic process; platelet activation; response to platinum ion; negative regulation of programmed cell death; negative regulation of apoptotic process; lipoprotein metabolic process; hemolysis by symbiont of host erythrocytes; bile acid and bile salt transport; response to organic substance; cellular response to starvation; transmembrane transport; maintenance of mitochondrion location; response to mercury ion; positive regulation of circadian sleep/wake cycle, non-REM sleep | |
| ALCAM | motor axon guidance; axon guidance; signal transduction; cell adhesion | |
| ALDH16A1 | - | |
| ALDH18A1 | cellular nitrogen compound metabolic process; small molecule metabolic process; cellular amino acid biosynthetic process; proline biosynthetic process | |
| ALDH1A1 | positive regulation of Ras GTPase activity; ethanol oxidation; cellular aldehyde metabolic process; xenobiotic metabolic process; small molecule metabolic process | |
| ALDH1A2 | pituitary gland development; blood vessel development; kidney development; liver development; regulation of endothelial cell proliferation; heart morphogenesis; vitamin A metabolic process; positive regulation of cell proliferation; midgut development; embryonic camera-type eye development; pancreas development; response to estradiol stimulus; response to vitamin A; response to cytokine stimulus; embryonic forelimb morphogenesis; hindbrain development; forebrain development; lung development; neuron differentiation; neural tube development; retinoic acid metabolic process; retinal metabolic process; neural crest cell development; negative regulation of cell proliferation; determination of bilateral symmetry; anterior/posterior pattern specification; proximal/distal pattern formation; cellular response to retinoic acid; face development; positive regulation of gene expression; retinoic acid receptor signaling pathway; positive regulation of apoptotic process; 9-cis-retinoic acid biosynthetic process; embryonic | |
| ALDH1B1 | carbohydrate metabolic process | |
| ALDH1L1 | 10-formyltetrahydrofolate catabolic process; biosynthetic process | |
| ALDH1L2 | 10-formyltetrahydrofolate catabolic process; biosynthetic process | |
| ALDH2 | ethanol oxidation; xenobiotic metabolic process; synaptic transmission; neurotransmitter biosynthetic process; small molecule metabolic process; alcohol metabolic process; carbohydrate metabolic process | |
| ALDH3A2 | oxidation-reduction process; cellular aldehyde metabolic process | |
| ALDH4A1 | proline catabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process; proline biosynthetic process; proline metabolic process | |
| ALDH6A1 | small molecule metabolic process; valine metabolic process; branched chain family amino acid catabolic process; thymine metabolic process; cellular nitrogen compound metabolic process | |
| ALDH8A1 | retinoic acid metabolic process; retinal metabolic process; 9-cis-retinoic acid biosynthetic process | |
| ALDH9A1 | small molecule metabolic process; kidney development; liver development; cellular aldehyde metabolic process; cellular nitrogen compound metabolic process; neurotransmitter biosynthetic process; hormone metabolic process; carnitine biosynthetic process; oxidation-reduction process | |
| ALDOA | platelet activation; ATP biosynthetic process; striated muscle contraction; actin filament organization; blood coagulation; regulation of cell shape; small molecule metabolic process; fructose 1,6-bisphosphate metabolic process; platelet degranulation; carbohydrate metabolic process; fructose metabolic process; glucose metabolic process; gluconeogenesis; glycolysis; muscle cell homeostasis; protein homotetramerization | |
| ALDOB | carbohydrate metabolic process; fructose metabolic process; vacuolar proton-transporting V-type ATPase complex assembly; small molecule metabolic process; positive regulation of ATPase activity; fructose 1,6-bisphosphate metabolic process; NADH oxidation; glycolysis; gluconeogenesis; glucose metabolic process; fructose catabolic process | |
| ALDOC | organ regeneration; small molecule metabolic process; response to hypoxia; carbohydrate metabolic process; fructose metabolic process; glucose metabolic process; gluconeogenesis; protein heterotetramerization; protein homotetramerization; fructose 1,6-bisphosphate metabolic process; response to organic cyclic compound; response to organic nitrogen; aging; apoptotic process; glycolysis | |
| ALG11 | cellular protein metabolic process; biosynthetic process; protein N-linked glycosylation via asparagine; post-translational protein modification; dolichol-linked oligosaccharide biosynthetic process | |
| ALG2 | protein N-linked glycosylation via asparagine; protein glycosylation in endoplasmic reticulum; post-translational protein modification; cellular protein metabolic process; biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; response to calcium ion | |
| ALG9 | GPI anchor biosynthetic process; cellular protein metabolic process; post-translational protein modification; dolichol-linked oligosaccharide biosynthetic process; protein N-linked glycosylation via asparagine | |
| ALK | signal transduction; activation of MAPK activity; transmembrane receptor protein tyrosine kinase signaling pathway; cell proliferation; phosphorylation; NIK/NF-kappaB cascade; regulation of apoptotic process; protein autophosphorylation; neuron development; positive regulation of NF-kappaB transcription factor activity | |
| ALKBH2 | oxidative DNA demethylation; DNA demethylation; oxidative demethylation; DNA dealkylation involved in DNA repair; DNA repair | |
| ALKBH7 | - | |
| ALKBH8 | tRNA methylation; response to DNA damage stimulus | |
| ALMS1 | triglyceride metabolic process; calcium-mediated signaling; epithelial cell proliferation; cilium assembly; glucose homeostasis; cholesterol homeostasis; G2/M transition of mitotic cell cycle; mitotic cell cycle; lipid metabolic process; sensory perception of sound; spermatid development; apoptotic process; regulation of fat cell differentiation; retinal rod cell development; developmental growth | |
| ALOX12 | anti-apoptosis; positive regulation of mitochondrial depolarization; cellular component movement; positive regulation of cell proliferation; positive regulation of endothelial cell migration; positive regulation of gene expression; leukotriene biosynthetic process; fatty acid oxidation; positive regulation of cell growth; negative regulation of cell killing; positive regulation of cell killing; superoxide anion generation; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of endothelial cell differentiation; positive regulation of cell adhesion; reactive oxygen species metabolic process | |
| ALOX12B | leukotriene biosynthetic process; lipid metabolic process; epidermis development | |
| ALOXE3 | leukotriene biosynthetic process | |
| ALPI | phosphorylation | |
| ALPK1 | protein phosphorylation | |
| ALPK2 | protein phosphorylation | |
| ALPK3 | heart development; multicellular organismal development; protein phosphorylation | |
| ALPL | skeletal system development; biomineral tissue development; response to lipopolysaccharide; response to vitamin D; response to antibiotic; response to glucocorticoid stimulus; cellular response to organic cyclic compound; cementum mineralization | |
| ALS2 | positive regulation of Rac GTPase activity; neuron projection morphogenesis; regulation of endosome size; positive regulation of protein kinase activity; regulation of Rho protein signal transduction; positive regulation of Rac protein signal transduction; positive regulation of protein serine/threonine kinase activity; cell death; axonogenesis; endosome organization; in utero embryonic development | |
| ALS2CL | regulation of Rho protein signal transduction; endosome organization | |
| ALS2CR11 | - | |
| ALX1 | positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; brain development; multicellular organismal development; regulation of transcription, DNA-dependent; cartilage condensation; negative regulation of transcription from RNA polymerase II promoter | |
| ALX3 | multicellular organismal development | |
| ALX4 | muscle organ development; hair follicle development; skeletal system development; palate development; pattern specification process; embryonic hindlimb morphogenesis; embryonic digit morphogenesis; regulation of apoptotic process; embryonic forelimb morphogenesis; limb morphogenesis; anterior/posterior pattern specification; post-embryonic development; positive regulation of transcription from RNA polymerase II promoter; digestive tract development; embryonic skeletal system morphogenesis | |
| AMBN | odontogenesis of dentin-containing tooth; bone mineralization; cell proliferation; cell adhesion | |
| AMBRA1 | cell differentiation; nervous system development; multicellular organismal development; autophagy | |
| AMDHD2 | N-acetylglucosamine metabolic process; carbohydrate metabolic process | |
| AMER1 | - | |
| AMER3 | - | |
| AMH | preantral ovarian follicle growth; urogenital system development; positive regulation of NF-kappaB transcription factor activity; response to drug; cell differentiation; response to organic cyclic compound; positive regulation of gene expression; aging; sex differentiation; sex determination; gonadal mesoderm development; cell-cell signaling; Mullerian duct regression | |
| AMHR2 | Mullerian duct regression; signal transduction; transforming growth factor beta receptor signaling pathway; sex differentiation | |
| AMIGO1 | axonal fasciculation; nervous system development; multicellular organismal development; heterophilic cell-cell adhesion; homophilic cell adhesion; cell adhesion; cell differentiation; myelination; positive regulation of axonogenesis | |
| AMIGO2 | cell adhesion; negative regulation of programmed cell death; heterophilic cell-cell adhesion; homophilic cell adhesion; anti-apoptosis | |
| AMOT | chemotaxis; gastrulation with mouth forming second; in utero embryonic development; cell-cell junction assembly; negative regulation of angiogenesis; vasculogenesis; regulation of cell migration; cellular protein localization; positive regulation of stress fiber assembly; positive regulation of cell size; positive regulation of blood vessel endothelial cell migration; negative regulation of vascular permeability; hippo signaling cascade; cell migration involved in gastrulation; positive regulation of embryonic development; actin cytoskeleton organization | |
| AMOTL2 | - | |
| AMPD1 | nucleotide metabolic process; purine-containing compound salvage; purine base metabolic process; IMP biosynthetic process; nucleobase-containing small molecule metabolic process; small molecule metabolic process | |
| AMPD2 | purine base metabolic process; purine nucleotide metabolic process; IMP biosynthetic process; purine-containing compound salvage; small molecule metabolic process; nucleobase-containing small molecule metabolic process | |
| AMPD3 | nucleobase-containing small molecule metabolic process; small molecule metabolic process; purine-containing compound salvage; purine base metabolic process; IMP biosynthetic process; AMP catabolic process; nucleotide metabolic process | |
| AMPH | positive regulation of GTPase activity; positive regulation of endocytosis; endocytosis; synaptic transmission; learning; synaptic vesicle endocytosis | |
| AMT | glycine catabolic process | |
| AMZ1 | proteolysis | |
| ANAPC11 | mitotic cell cycle; mitosis; mitotic cell cycle spindle assembly checkpoint; protein ubiquitination; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; cell cycle checkpoint | |
| ANAPC5 | cell cycle checkpoint; G2/M transition of mitotic cell cycle; protein K11-linked ubiquitination; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; mitotic anaphase; mitotic cell cycle; ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; mitotic cell cycle spindle assembly checkpoint; protein ubiquitination; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division | |
| ANGEL1 | - | |
| ANGEL2 | - | |
| ANGPT1 | positive regulation of receptor internalization; negative regulation of endothelial cell apoptosis; positive regulation of ERK1 and ERK2 cascade; positive regulation of protein kinase B signaling cascade; positive chemotaxis; leukocyte migration; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of blood vessel endothelial cell migration; Tie receptor signaling pathway; heparin biosynthetic process; cell differentiation; regulation of satellite cell proliferation; positive regulation of endothelial cell migration; blood coagulation; multicellular organismal development; activation of transmembrane receptor protein tyrosine kinase activity; signal transduction; negative regulation of cell adhesion; anti-apoptosis; sprouting angiogenesis; regulation of endothelial cell proliferation; positive regulation of protein ubiquitination; protein localization at cell surface; negative regulation of apoptotic process; negative regulation of vascular permeability | |
| ANGPT2 | maternal process involved in female pregnancy; negative regulation of positive chemotaxis; leukocyte migration; Tie receptor signaling pathway; negative regulation of blood vessel endothelial cell migration; response to hypoxia; signal transduction; multicellular organismal development; germ cell development; blood coagulation; response to radiation; response to mechanical stimulus; response to glucose stimulus; negative regulation of cell-substrate adhesion; response to organic cyclic compound; response to activity; negative regulation of angiogenesis; cell differentiation; organ regeneration; positive regulation of angiogenesis | |
| ANGPTL1 | signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway | |
| ANGPTL2 | signal transduction; multicellular organismal development | |
| ANGPTL3 | lipid homeostasis; cell-matrix adhesion; negative regulation of catalytic activity; cholesterol homeostasis; positive regulation of cell migration; lipid storage; negative regulation of phospholipase activity; response to hormone stimulus; phospholipid catabolic process; positive regulation of angiogenesis; cholesterol metabolic process; integrin-mediated signaling pathway; signal transduction; phospholipid metabolic process; fatty acid metabolic process; glycerol metabolic process; artery morphogenesis; acylglycerol homeostasis; positive regulation of lipid catabolic process; negative regulation of lipoprotein lipase activity; phospholipid homeostasis; triglyceride homeostasis | |
| ANGPTL5 | signal transduction | |
| ANK1 | maintenance of epithelial cell apical/basal polarity; axon guidance; signal transduction; cytoskeleton organization; exocytosis | |
| ANK2 | axon guidance; signal transduction | |
| ANK3 | establishment of protein localization; signal transduction | |
| ANKAR | - | |
| ANKEF1 | - | |
| ANKFN1 | - | |
| ANKFY1 | - | |
| ANKH | inorganic diphosphate transport; skeletal system development; regulation of bone mineralization; locomotory behavior; transport | |
| ANKLE2 | - | |
| ANKMY1 | - | |
| ANKMY2 | - | |
| ANKRD11 | tissue homeostasis; skeletal system morphogenesis; head morphogenesis; bone development; multicellular organism growth; in utero embryonic development | |
| ANKRD12 | - | |
| ANKRD13B | - | |
| ANKRD13D | - | |
| ANKRD16 | - | |
| ANKRD17 | interspecies interaction between organisms | |
| ANKRD2 | muscle organ development; muscle contraction | |
| ANKRD22 | - | |
| ANKRD26 | - | |
| ANKRD27 | early endosome to late endosome transport | |
| ANKRD34A | - | |
| ANKRD34B | - | |
| ANKRD35 | - | |
| ANKRD44 | - | |
| ANKRD46 | - | |
| ANKRD50 | - | |
| ANKRD53 | - | |
| ANKRD55 | - | |
| ANKRD7 | male gonad development | |
| ANKRD9 | - | |
| ANKS1A | substrate-dependent cell migration; ephrin receptor signaling pathway; neuron remodeling | |
| ANKS3 | - | |
| ANKS4B | - | |
| ANKS6 | - | |
| ANKZF1 | - | |
| ANLN | regulation of exit from mitosis; mitosis; cell cycle; septin ring assembly; cytokinesis | |
| ANO10 | cell death; ion transport | |
| ANO3 | ion transport | |
| ANO4 | ion transport | |
| ANO5 | ion transport | |
| ANO6 | phosphatidylserine exposure on blood platelet; ion transport; activation of blood coagulation via clotting cascade | |
| ANO7 | ion transport | |
| ANO9 | ion transport | |
| ANP32E | negative regulation of catalytic activity | |
| ANPEP | angiogenesis; interspecies interaction between organisms; negative regulation of renal sodium excretion; cell differentiation; metabolic process; multicellular organismal development; cellular aromatic compound metabolic process; proteolysis | |
| ANTXR1 | actin cytoskeleton reorganization; substrate adhesion-dependent cell spreading | |
| ANXA10 | - | |
| ANXA4 | negative regulation of coagulation; signal transduction; anti-apoptosis | |
| ANXA7 | cellular calcium ion homeostasis; hemostasis; cell proliferation; regulation of cell shape; response to salt stress; cellular water homeostasis; social behavior | |
| ANXA9 | cell-cell adhesion | |
| AOAH | lipid metabolic process; inflammatory response; lipopolysaccharide metabolic process; negative regulation of inflammatory response | |
| AOC1 | - | |
| AOC2 | catecholamine metabolic process; visual perception; amine metabolic process | |
| AOX1 | inflammatory response; reactive oxygen species metabolic process | |
| AP1AR | protein transport | |
| AP1B1 | intracellular protein transport; post-Golgi vesicle-mediated transport; regulation of defense response to virus by virus; cellular membrane organization; viral reproduction; endocytosis | |
| AP1G1 | intracellular protein transport; viral reproduction; endocytosis; post-Golgi vesicle-mediated transport; cellular membrane organization; regulation of defense response to virus by virus | |
| AP1M1 | cellular membrane organization; regulation of defense response to virus by virus; interspecies interaction between organisms; endosome to melanosome transport; melanosome organization; vesicle-mediated transport; viral reproduction; post-Golgi vesicle-mediated transport; intracellular protein transport | |
| AP2M1 | negative regulation of epidermal growth factor receptor signaling pathway; vesicle-mediated transport; nerve growth factor receptor signaling pathway; cellular membrane organization; viral reproduction; axon guidance; synaptic transmission; epidermal growth factor receptor signaling pathway; intracellular protein transport; transport; regulation of defense response to virus by virus | |
| AP2S1 | vesicle-mediated transport; regulation of endocytosis; negative regulation of epidermal growth factor receptor signaling pathway; clathrin coat assembly; viral reproduction; protein transport; axon guidance; synaptic transmission; epidermal growth factor receptor signaling pathway; intracellular protein transport; transport; regulation of defense response to virus by virus; nerve growth factor receptor signaling pathway | |
| AP3B1 | antigen processing and presentation, exogenous lipid antigen via MHC class Ib; endocytosis; blood coagulation; antigen processing and presentation; melanosome organization; protein targeting to lysosome; positive regulation of NK T cell differentiation; intracellular protein transport | |
| AP3M1 | protein targeting to lysosome; intracellular protein transport; vesicle-mediated transport | |
| AP3M2 | intracellular protein transport; vesicle-mediated transport | |
| AP3S1 | transport; intracellular protein transport; insulin receptor signaling pathway; vesicle-mediated transport | |
| AP4B1 | intracellular protein transport; vesicle-mediated transport; transport | |
| AP4E1 | intracellular protein transport; vesicle-mediated transport | |
| AP4M1 | intracellular protein transport; vesicle-mediated transport | |
| AP5M1 | intracellular protein transport; vesicle-mediated transport | |
| APAF1 | apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; induction of apoptosis by intracellular signals; nervous system development; defense response; activation of cysteine-type endopeptidase activity involved in apoptotic process; intrinsic apoptotic signaling pathway; regulation of apoptotic process | |
| APBA1 | in utero embryonic development; protein complex assembly; intracellular protein transport; cell adhesion; synaptic transmission; nervous system development; locomotory behavior; axon cargo transport; regulation of gene expression; glutamate secretion; gamma-aminobutyric acid secretion; multicellular organism growth | |
| APBA2 | nervous system development; protein transport | |
| APBB1IP | blood coagulation; signal transduction; platelet activation | |
| APBB2 | intracellular signal transduction; regulation of transcription, DNA-dependent; cell cycle arrest; negative regulation of cell growth; negative regulation of S phase of mitotic cell cycle | |
| APBB3 | intracellular signal transduction | |
| APC | axis specification; negative regulation of canonical Wnt receptor signaling pathway; cell migration; response to DNA damage stimulus; negative regulation of microtubule depolymerization; cell cycle arrest; mitotic metaphase/anaphase transition; mitotic cell cycle spindle assembly checkpoint; cell adhesion; establishment or maintenance of cell polarity; axonogenesis; negative regulation of cell proliferation; anterior/posterior pattern specification; dorsal/ventral pattern formation; proximal/distal pattern formation; cellular component disassembly involved in apoptosis; positive regulation of cell migration; positive regulation of epithelial cell differentiation; pancreas development; positive regulation of microtubule polymerization; cytoplasmic microtubule organization; neuron projection development; positive regulation of pseudopodium assembly; regulation of microtubule-based process; T cell differentiation in thymus; regulation of cell cycle; chromosome organization; regulation of nitrogen compound metabo | |
| APC2 | negative regulation of catenin import into nucleus; negative regulation of canonical Wnt receptor signaling pathway; Wnt receptor signaling pathway | |
| APCDD1 | negative regulation of Wnt receptor signaling pathway; hair follicle development | |
| APCS | protein folding; chaperone-mediated protein complex assembly; acute-phase response | |
| APEH | proteolysis | |
| APEX2 | DNA repair; DNA recombination; cell cycle | |
| API5 | apoptotic process; anti-apoptosis | |
| APLF | response to DNA damage stimulus; double-strand break repair; single strand break repair | |
| APLNR | regulation of body fluid levels; G-protein coupled receptor signaling pathway | |
| APLP1 | extracellular matrix organization; organ morphogenesis; cell death; nervous system development; inhibition of adenylate cyclase activity by G-protein signaling pathway; cell adhesion; apoptotic process; endocytosis; regulation of translation; mRNA polyadenylation; negative regulation of cAMP biosynthetic process; forebrain development; cellular response to norepinephrine stimulus | |
| APMAP | - | |
| APOA1 | high-density lipoprotein particle assembly; glucocorticoid metabolic process; positive regulation of cholesterol esterification; negative regulation of very-low-density lipoprotein particle remodeling; lipid storage; platelet activation; regulation of intestinal cholesterol absorption; cholesterol transport; adrenal gland development; Cdc42 protein signal transduction; cholesterol efflux; phospholipid efflux; high-density lipoprotein particle remodeling; cholesterol metabolic process; high-density lipoprotein particle clearance; lipoprotein metabolic process; lipoprotein biosynthetic process; cholesterol homeostasis; blood vessel endothelial cell migration; reverse cholesterol transport; cellular lipid metabolic process; small molecule metabolic process; negative regulation of interleukin-1 beta secretion; protein stabilization; positive regulation of hydrolase activity; negative regulation of hydrolase activity; steroid metabolic process; cholesterol import; transmembrane transport; positive regulation of tr | |
| APOA4 | high-density lipoprotein particle remodeling; very-low-density lipoprotein particle remodeling; chylomicron remodeling; phospholipid efflux; cholesterol efflux; regulation of cholesterol transport; regulation of intestinal cholesterol absorption; chylomicron assembly; removal of superoxide radicals; protein-lipid complex assembly; lipid homeostasis; positive regulation of lipoprotein lipase activity; phosphatidylcholine metabolic process; positive regulation of fatty acid biosynthetic process; small molecule metabolic process; multicellular organismal lipid catabolic process; reverse cholesterol transport; negative regulation of plasma lipoprotein particle oxidation; hydrogen peroxide catabolic process; cholesterol homeostasis; lipoprotein metabolic process; response to stilbenoid; positive regulation of cholesterol esterification; cholesterol metabolic process; leukocyte cell-cell adhesion; response to lipid hydroperoxide; lipid transport; transport; lipid metabolic process; innate immune response in mucosa; | |
| APOB | very-low-density lipoprotein particle assembly; response to carbohydrate stimulus; low-density lipoprotein particle remodeling; response to lipopolysaccharide; sperm motility; cholesterol transport; lipid catabolic process; positive regulation of cholesterol storage; positive regulation of lipid storage; positive regulation of macrophage derived foam cell differentiation; response to selenium ion; post-embryonic development; triglyceride catabolic process; low-density lipoprotein particle clearance; lipoprotein metabolic process; lipoprotein biosynthetic process; lipoprotein catabolic process; cholesterol homeostasis; lipoprotein transport; small molecule metabolic process; regulation of cholesterol biosynthetic process; artery morphogenesis; leukocyte migration; cellular response to tumor necrosis factor; cellular response to prostaglandin stimulus; fertilization; in utero embryonic development; lipid metabolic process; triglyceride mobilization; transport; response to virus; receptor-mediated endocytosis; n | |
| APOBEC2 | DNA demethylation; mRNA modification; cytidine deamination; mRNA processing | |
| APOBEC3G | interspecies interaction between organisms; negative regulation of viral genome replication; cytidine deamination; negative regulation of retroviral genome replication; negative regulation of transposition; response to virus; innate immune response; positive regulation of defense response to virus by host; viral reproduction; negative regulation of viral reproduction; base conversion or substitution editing; DNA cytosine deamination | |
| APOC3 | triglyceride homeostasis; negative regulation of fatty acid biosynthetic process; negative regulation of lipid metabolic process; negative regulation of receptor-mediated endocytosis; negative regulation of lipid catabolic process; negative regulation of lipoprotein lipase activity; negative regulation of cholesterol import; negative regulation of high-density lipoprotein particle clearance; cholesterol homeostasis; negative regulation of very-low-density lipoprotein particle clearance; negative regulation of very-low-density lipoprotein particle remodeling; negative regulation of triglyceride catabolic process; cholesterol metabolic process; small molecule metabolic process; reverse cholesterol transport; lipoprotein metabolic process; chylomicron remnant clearance; very-low-density lipoprotein particle assembly; high-density lipoprotein particle remodeling; phospholipid efflux; cholesterol efflux; Cdc42 protein signal transduction; triglyceride catabolic process; negative regulation of low-density lipoprote | |
| APOL1 | transport; lipid transport; steroid metabolic process; chloride transport; cholesterol metabolic process; cytolysis; killing of cells of other organism; lipoprotein metabolic process; innate immune response | |
| APOL3 | positive regulation of I-kappaB kinase/NF-kappaB cascade; transport; lipid transport; inflammatory response; signal transduction; lipoprotein metabolic process | |
| APOL5 | lipid transport; lipoprotein metabolic process; lipid metabolic process; transport | |
| APOPT1 | positive regulation of release of cytochrome c from mitochondria; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of smooth muscle cell apoptosis; induction of apoptosis by intracellular signals | |
| APP | cell adhesion; axon cargo transport; locomotory behavior; mating behavior; blood coagulation; axonogenesis; Notch signaling pathway; regulation of epidermal growth factor-activated receptor activity; G2 phase of mitotic cell cycle; cell death; adult locomotory behavior; visual learning; regulation of gene expression; axon midline choice point recognition; neuron remodeling; dendrite development; platelet activation; extracellular matrix organization; forebrain development; neuron projection development; ionotropic glutamate receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; endocytosis; smooth endoplasmic reticulum calcium ion homeostasis; neuron apoptosis; synaptic growth at neuromuscular junction; neuromuscular process controlling balance; regulation of synapse structure and activity; collateral sprouting in absence of injury; positive regulation of transcription from RNA polymerase II promoter; positive regulation of mitotic cell cycle; negativ | |
| APPBP2 | intracellular transport; intracellular protein transport | |
| APPL1 | regulation of glucose import; regulation of establishment of protein localization in plasma membrane; cell cycle; regulation of apoptotic process; insulin receptor signaling pathway; apoptotic process; cell proliferation; signal transduction | |
| APPL2 | cell proliferation; signal transduction; cell cycle | |
| APRT | adenine salvage; purine base metabolic process; purine ribonucleoside salvage; lactation; grooming behavior; nucleoside metabolic process; purine-containing compound salvage; small molecule metabolic process; nucleobase-containing small molecule metabolic process | |
| AQP1 | renal water transport; cGMP biosynthetic process; potassium ion transport; water transport; cell volume homeostasis; carbon dioxide transport; cellular response to hydrogen peroxide; ammonium transport; cellular response to inorganic substance; cellular response to mechanical stimulus; cellular response to copper ion; cellular response to mercury ion; cellular response to retinoic acid; cellular response to cAMP; cellular response to hypoxia; cellular response to salt stress; cellular hyperosmotic response; cellular response to dexamethasone stimulus; cellular response to nitric oxide; potassium ion transmembrane transport; maintenance of symbiont-containing vacuole via substance secreted by host; cellular homeostasis; transmembrane transport; multicellular organismal water homeostasis; positive regulation of fibroblast proliferation; positive regulation of saliva secretion; positive regulation of angiogenesis; negative regulation of apoptotic process; response to drug; odontogenesis; carbon dioxide transmemb | |
| AQP11 | protein homooligomerization; water transport; ion transport; glycerol transport; urea transport; endosomal lumen acidification; kidney development | |
| AQP5 | water transport; excretion; carbon dioxide transport; pancreatic juice secretion; odontogenesis; saliva secretion; camera-type eye morphogenesis; transmembrane transport | |
| AQP8 | water transport; canalicular bile acid transport; transmembrane transport; cellular response to cAMP; transport | |
| AQR | nuclear mRNA splicing, via spliceosome; RNA splicing | |
| AR | regulation of transcription, DNA-dependent; positive regulation of NF-kappaB transcription factor activity; negative regulation of integrin biosynthetic process; positive regulation of integrin biosynthetic process; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase III promoter; male sex differentiation; regulation of developmental growth; organ formation; male genitalia morphogenesis; negative regulation of epithelial cell proliferation; regulation of catalytic activity; transcription, DNA-dependent; activation of prostate induction by androgen receptor signaling pathway; morphogenesis of an epithelial fold; lateral sprouting involved in mammary gland duct morphogenesis; regulation of prostatic bud formation; prostate gland growth; prostate gland epithelium morphogenesis; epithelial cell differentiation involved in prostate gland development; tertiary branching involved in mammary | |
| ARAP1 | regulation of cellular component movement; negative regulation of stress fiber assembly; positive regulation of filopodium assembly; regulation of small GTPase mediated signal transduction; positive regulation of Cdc42 GTPase activity; regulation of ARF GTPase activity; actin filament reorganization involved in cell cycle; regulation of cell shape; signal transduction; small GTPase mediated signal transduction | |
| ARAP2 | signal transduction; regulation of small GTPase mediated signal transduction; regulation of ARF GTPase activity; small GTPase mediated signal transduction | |
| ARAP3 | negative regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; negative regulation of Rac protein signal transduction; negative regulation of cell migration; positive regulation of Rho GTPase activity; regulation of ARF GTPase activity; vesicle-mediated transport; regulation of cell shape; small GTPase mediated signal transduction; signal transduction; cytoskeleton organization | |
| ARC | learning; anterior/posterior pattern specification; regulation of neuronal synaptic plasticity; cell migration; regulation of cell morphogenesis; endoderm development; multicellular organismal development; cytoskeleton organization; endocytosis | |
| ARCN1 | transport; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; cellular membrane organization; vesicle-mediated transport; COPI coating of Golgi vesicle | |
| AREL1 | - | |
| ARF1 | cellular copper ion homeostasis; GTP catabolic process; post-Golgi vesicle-mediated transport; small GTPase mediated signal transduction; protein transport; viral reproduction; cellular membrane organization; vesicle-mediated transport; COPI coating of Golgi vesicle; regulation of defense response to virus by virus; retrograde vesicle-mediated transport, Golgi to ER | |
| ARFGAP1 | cellular membrane organization; endoplasmic reticulum unfolded protein response; vesicle-mediated transport; regulation of ARF GTPase activity; COPI coating of Golgi vesicle; protein transport; activation of signaling protein activity involved in unfolded protein response; retrograde vesicle-mediated transport, Golgi to ER | |
| ARFGAP2 | regulation of ARF GTPase activity; protein transport; vesicle-mediated transport | |
| ARFGAP3 | vesicle-mediated transport; protein secretion; intracellular protein transport; regulation of ARF GTPase activity | |
| ARFGEF2 | exocytosis; intracellular signal transduction; regulation of ARF protein signal transduction; vesicle-mediated transport | |
| ARFIP2 | ruffle organization; actin cytoskeleton organization; lamellipodium assembly; small GTPase mediated signal transduction; cellular component movement | |
| ARFRP1 | Golgi to plasma membrane protein transport; GTP catabolic process; signal transduction; small GTPase mediated signal transduction; gastrulation; protein localization in Golgi apparatus; retrograde transport, endosome to Golgi | |
| ARGFX | - | |
| ARHGAP10 | apoptotic process; regulation of small GTPase mediated signal transduction; filopodium assembly; regulation of apoptotic process; small GTPase mediated signal transduction; signal transduction; cytoskeleton organization | |
| ARHGAP11A | signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction | |
| ARHGAP12 | signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction | |
| ARHGAP15 | signal transduction; small GTPase mediated signal transduction; regulation of cell shape; positive regulation of Rac GTPase activity; regulation of small GTPase mediated signal transduction | |
| ARHGAP17 | small GTPase mediated signal transduction; signal transduction; calcium ion-dependent exocytosis; regulation of small GTPase mediated signal transduction; actin filament organization | |
| ARHGAP19 | small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; signal transduction | |
| ARHGAP21 | signal transduction | |
| ARHGAP22 | regulation of small GTPase mediated signal transduction; cell differentiation; multicellular organismal development; small GTPase mediated signal transduction; signal transduction; regulation of transcription, DNA-dependent; angiogenesis | |
| ARHGAP24 | regulation of small GTPase mediated signal transduction; multicellular organismal development; angiogenesis; signal transduction; cell differentiation; small GTPase mediated signal transduction | |
| ARHGAP25 | signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction | |
| ARHGAP28 | signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction | |
| ARHGAP29 | regulation of small GTPase mediated signal transduction; positive regulation of Rho GTPase activity; small GTPase mediated signal transduction; Rho protein signal transduction | |
| ARHGAP30 | regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction | |
| ARHGAP31 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction | |
| ARHGAP32 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction | |
| ARHGAP33 | protein transport; signal transduction | |
| ARHGAP36 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction | |
| ARHGAP39 | regulation of small GTPase mediated signal transduction; axon guidance; small GTPase mediated signal transduction; signal transduction | |
| ARHGAP4 | cytoskeleton organization; apoptotic process; signal transduction; small GTPase mediated signal transduction; Rho protein signal transduction; induction of apoptosis by extracellular signals; positive regulation of Rho GTPase activity; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction | |
| ARHGAP6 | regulation of GTPase activity; regulation of small GTPase mediated signal transduction; negative regulation of stress fiber assembly; negative regulation of focal adhesion assembly; signal transduction; actin filament polymerization; positive regulation of phospholipase activity; Rho protein signal transduction; actin filament organization; activation of phospholipase C activity; small GTPase mediated signal transduction; positive regulation of Rho GTPase activity | |
| ARHGAP9 | small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity; signal transduction | |
| ARHGDIB | Rho protein signal transduction; regulation of small GTPase mediated signal transduction; actin cytoskeleton organization; multicellular organismal development; small GTPase mediated signal transduction; negative regulation of cell adhesion; immune response; cellular component movement | |
| ARHGDIG | regulation of protein localization; regulation of small GTPase mediated signal transduction; regulation of catalytic activity; negative regulation of cell adhesion; small GTPase mediated signal transduction; Rho protein signal transduction | |
| ARHGEF1 | Rho protein signal transduction; cell proliferation; regulation of Rho protein signal transduction; termination of G-protein coupled receptor signaling pathway; negative regulation of axonogenesis; nerve growth factor receptor signaling pathway; regulation of axonogenesis | |
| ARHGEF10 | positive regulation of GTP catabolic process; spindle assembly involved in mitosis; positive regulation of stress fiber assembly; centrosome duplication; regulation of Rho protein signal transduction; myelination in peripheral nervous system | |
| ARHGEF10L | positive regulation of Rho GTPase activity; regulation of Rho protein signal transduction; positive regulation of transcription via sterol regulatory element binding; positive regulation of stress fiber assembly | |
| ARHGEF11 | Rho protein signal transduction; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; termination of G-protein coupled receptor signaling pathway; cytokinesis; regulation of cell growth; apoptotic process; cellular component movement; striated muscle contraction; G-protein coupled receptor signaling pathway; small GTPase mediated signal transduction; regulation of Rho protein signal transduction; actin cytoskeleton organization; establishment of cell polarity; induction of apoptosis by extracellular signals; axon guidance | |
| ARHGEF12 | regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; termination of G-protein coupled receptor signaling pathway; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; axon guidance; small GTPase mediated signal transduction; G-protein coupled receptor signaling pathway; apoptotic process | |
| ARHGEF15 | negative regulation of synapse maturation; positive regulation of stress fiber assembly; regulation of catalytic activity; regulation of Rho protein signal transduction | |
| ARHGEF16 | regulation of Rho protein signal transduction; activation of Cdc42 GTPase activity; activation of Rac GTPase activity; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction; apoptotic process; induction of apoptosis by extracellular signals; cell chemotaxis; positive regulation of establishment of protein localization in plasma membrane; small GTPase mediated signal transduction | |
| ARHGEF17 | nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction; regulation of Rho protein signal transduction; actin cytoskeleton organization; induction of apoptosis by extracellular signals; small GTPase mediated signal transduction; apoptotic process | |
| ARHGEF18 | apoptotic process; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; regulation of Rho protein signal transduction; actin cytoskeleton organization; induction of apoptosis by extracellular signals; regulation of cell shape; small GTPase mediated signal transduction | |
| ARHGEF19 | regulation of actin cytoskeleton organization; wound healing; regulation of Rho protein signal transduction; positive regulation of Rho GTPase activity | |
| ARHGEF2 | cell cycle; establishment of mitotic spindle orientation; mitosis; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals; regulation of Rho protein signal transduction; intracellular signal transduction; regulation of cell proliferation; nerve growth factor receptor signaling pathway; negative regulation of neurogenesis; regulation of small GTPase mediated signal transduction; positive regulation of NF-kappaB transcription factor activity; cell division; negative regulation of microtubule depolymerization; actin filament organization; apoptotic process; intracellular protein transport; cell morphogenesis | |
| ARHGEF3 | nerve growth factor receptor signaling pathway; apoptotic process; small GTPase mediated signal transduction; Rho protein signal transduction; induction of apoptosis by extracellular signals; regulation of small GTPase mediated signal transduction; regulation of Rho protein signal transduction | |
| ARHGEF37 | regulation of Rho protein signal transduction | |
| ARHGEF38 | regulation of Rho protein signal transduction | |
| ARHGEF4 | lamellipodium assembly; apoptotic process; nerve growth factor receptor signaling pathway; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals; filopodium assembly; intracellular signal transduction; regulation of small GTPase mediated signal transduction; regulation of Rho protein signal transduction | |
| ARHGEF40 | regulation of Rho protein signal transduction | |
| ARHGEF6 | induction of apoptosis by extracellular signals; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of GTPase activity; regulation of Rho protein signal transduction; cell junction assembly; small GTPase mediated signal transduction; JNK cascade; apoptotic process | |
| ARHGEF7 | nervous system development; apoptotic process; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; regulation of Rho protein signal transduction; signal transduction; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals | |
| ARID1A | chromatin organization; intracellular estrogen receptor signaling pathway; nervous system development; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; nucleosome disassembly; positive regulation of transcription, DNA-dependent; chromatin-mediated maintenance of transcription; androgen receptor signaling pathway; nucleosome mobilization; glucocorticoid receptor signaling pathway | |
| ARID1B | nervous system development; chromatin modification; regulation of transcription, DNA-dependent; chromatin-mediated maintenance of transcription | |
| ARID2 | nucleosome disassembly; chromatin modification; regulation of transcription, DNA-dependent | |
| ARID3A | regulation of transcription, DNA-dependent | |
| ARID3C | regulation of transcription, DNA-dependent | |
| ARID4A | negative regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| ARID4B | regulation of transcription, DNA-dependent | |
| ARID5A | negative regulation of transcription, DNA-dependent | |
| ARID5B | post-embryonic development; nitrogen compound metabolic process; negative regulation of transcription, DNA-dependent; fat cell differentiation; multicellular organism growth; adrenal gland development; fibroblast migration; fat pad development; adipose tissue development; face morphogenesis; female gonad development; male gonad development; liver development; kidney development; platelet-derived growth factor receptor signaling pathway; cell development; muscle organ morphogenesis; skeletal system morphogenesis; positive regulation of sequence-specific DNA binding transcription factor activity; palate development | |
| ARIH1 | ubiquitin-dependent protein catabolic process; protein ubiquitination; cytokine-mediated signaling pathway | |
| ARIH2 | protein polyubiquitination; multicellular organismal development; protein K63-linked ubiquitination; hemopoietic stem cell proliferation; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; developmental cell growth | |
| ARL11 | small GTPase mediated signal transduction | |
| ARL2 | maintenance of protein location in nucleus; tight junction assembly; centrosome organization; negative regulation of GTPase activity; regulation of microtubule polymerization; acetylcholine transport; GTP catabolic process; positive regulation of cell-substrate adhesion; tubulin complex assembly; cell cycle; small GTPase mediated signal transduction; positive regulation of microtubule polymerization | |
| ARL3 | cilium morphogenesis; photoreceptor cell development; protein transport; small GTPase mediated signal transduction; cell cycle; kidney development; cytokinesis | |
| ARL4C | GTP catabolic process; transport; endocytic recycling; small GTPase mediated signal transduction | |
| ARL5A | small GTPase mediated signal transduction | |
| ARL6IP5 | negative regulation of transport; L-glutamate transport | |
| ARL8A | cell division; small GTPase mediated signal transduction; mitosis; chromosome segregation; cell cycle; GTP catabolic process | |
| ARMC12 | - | |
| ARMC3 | - | |
| ARMC4 | - | |
| ARMC5 | - | |
| ARMC6 | - | |
| ARMC9 | - | |
| ARMCX1 | - | |
| ARMCX2 | - | |
| ARMCX3 | - | |
| ARMCX5 | - | |
| ARNT | response to hypoxia; positive regulation of hormone biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of glycolysis; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; embryonic placenta development; positive regulation of endothelial cell proliferation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation vascular endothelial growth factor production; cell differentiation; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of protein sumoylation; mRNA transcription from RNA polymerase II promoter; positive regulation of erythrocyte differentiation | |
| ARNT2 | positive regulation of cell proliferation; response to hypoxia; in utero embryonic development; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; response to estradiol stimulus; central nervous system development | |
| ARNTL | positive regulation of transcription from RNA polymerase II promoter; circadian rhythm | |
| ARNTL2 | circadian rhythm; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; entrainment of circadian clock | |
| ARPC1A | regulation of actin filament polymerization; actin cytoskeleton organization | |
| ARPC1B | cellular component movement; regulation of actin filament polymerization | |
| ARPP21 | cellular response to heat | |
| ARRB1 | regulation of transcription, DNA-dependent; G-protein coupled receptor internalization; positive regulation of ERK1 and ERK2 cascade; positive regulation of transcription from RNA polymerase II promoter; histone H4 acetylation; positive regulation of GTPase activity; proteasomal ubiquitin-dependent protein catabolic process; stress fiber assembly; negative regulation of catalytic activity; positive regulation of histone acetylation; positive regulation of Rho protein signal transduction; negative regulation of interleukin-8 production; negative regulation of interleukin-6 production; negative regulation of protein ubiquitination; transcription from RNA polymerase II promoter; post-Golgi vesicle-mediated transport; blood coagulation; negative regulation of signal transduction; protein transport; cellular membrane organization; protein ubiquitination; platelet activation; negative regulation of NF-kappaB transcription factor activity | |
| ARRDC1-AS1 | - | |
| ARRDC2 | - | |
| ARRDC3 | signal transduction | |
| ARSD | - | |
| ARSF | - | |
| ARSG | sulfur compound metabolic process | |
| ARSH | - | |
| ARSI | - | |
| ARSJ | - | |
| ARSK | - | |
| ARV1 | sphingolipid metabolic process; lipid metabolic process | |
| ARVCF | multicellular organismal development; cell adhesion | |
| ARX | positive regulation of organ growth; cell proliferation in forebrain; axon guidance; regulation of cell proliferation; embryonic olfactory bulb interneuron precursor migration; cell differentiation; cerebral cortex GABAergic interneuron migration; cerebral cortex tangential migration; olfactory bulb development; globus pallidus development; nervous system development; multicellular organismal development; neuron migration | |
| ASAH2 | glycosphingolipid metabolic process; ceramide metabolic process; lipid metabolic process; sphingolipid metabolic process; small molecule metabolic process; signal transduction; apoptotic process | |
| ASAP2 | regulation of ARF GTPase activity; positive regulation of catalytic activity | |
| ASAP3 | regulation of ARF GTPase activity | |
| ASB11 | intracellular signal transduction | |
| ASB14 | intracellular signal transduction | |
| ASB15 | intracellular signal transduction | |
| ASB17 | intracellular signal transduction | |
| ASB2 | signal transduction; intracellular signal transduction | |
| ASB4 | intracellular signal transduction | |
| ASB5 | intracellular signal transduction | |
| ASB9 | protein ubiquitination; intracellular signal transduction; positive regulation of protein catabolic process | |
| ASCC2 | regulation of transcription, DNA-dependent | |
| ASCC3 | regulation of transcription, DNA-dependent | |
| ASCL3 | regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent | |
| ASCL4 | regulation of transcription from RNA polymerase II promoter; skin development | |
| ASGR1 | receptor-mediated endocytosis; cellular response to extracellular stimulus | |
| ASGR2 | endocytosis; cell surface receptor signaling pathway; glycoprotein metabolic process; bone mineralization; regulation of protein stability; lipid homeostasis | |
| ASH1L | DNA packaging; chromatin modification; cell-cell signaling; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| ASH2L | histone H3-K4 methylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; response to DNA damage stimulus; positive regulation of cell proliferation; chromatin modification; hemopoiesis; response to estrogen stimulus; positive regulation of transcription from RNA polymerase II promoter | |
| ASIC1 | ion transport; sodium ion transport; calcium ion transport; signal transduction; response to pH; transport | |
| ASIC3 | transport; ion transport; signal transduction; sensory perception; sodium ion transmembrane transport | |
| ASIC5 | ion transport | |
| ASIP | signal transduction; cell-cell signaling; adult feeding behavior; generation of precursor metabolites and energy; hormone-mediated signaling pathway; melanosome transport; melanosome organization; regulation of molecular function, epigenetic; melanin biosynthetic process; pigmentation; genetic imprinting | |
| ASL | response to acid; cellular response to tumor necrosis factor; cellular response to glucagon stimulus; cellular response to hypoxia; aging; midgut development; arginine catabolic process; internal protein amino acid acetylation; liver development; kidney development; arginine biosynthetic process via ornithine; argininosuccinate metabolic process; cellular response to dexamethasone stimulus; urea cycle; response to drug; response to lipopolysaccharide; small molecule metabolic process; response to steroid hormone stimulus; response to growth hormone stimulus; diaphragm development; cellular response to ammonium ion; cellular response to cAMP; cellular response to interferon-gamma; cellular nitrogen compound metabolic process; ammonia assimilation cycle; response to amine stimulus; response to zinc ion; post-embryonic development; cellular amino acid biosynthetic process; locomotory behavior; response to nutrient | |
| ASNA1 | transport; arsenite transport; detoxification of arsenic-containing substance | |
| ASNSD1 | glutamine metabolic process; cellular amino acid biosynthetic process; asparagine biosynthetic process | |
| ASPH | face morphogenesis; palate development; peptidyl-aspartic acid hydroxylation; limb morphogenesis; peptidyl-amino acid modification; pattern specification process; muscle contraction; negative regulation of cell proliferation | |
| ASPHD1 | peptidyl-amino acid modification | |
| ASPM | negative regulation of asymmetric cell division; cell cycle; mitosis; forebrain neuroblast division; negative regulation of neuron differentiation; cell division; maintenance of centrosome location | |
| ASPN | bone mineralization; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of tooth mineralization | |
| ASPRV1 | skin development; protein processing; proteolysis | |
| ASPSCR1 | intracellular protein transport; glucose homeostasis; regulation of glucose import | |
| ASTE1 | DNA repair | |
| ASTL | proteolysis | |
| ASTN1 | cell migration; neuron cell-cell adhesion; cell adhesion | |
| ASTN2 | - | |
| ASUN | cell division; cell cycle; mitosis; regulation of mitotic cell cycle; sperm motility; regulation of fertilization | |
| ASXL1 | regulation of transcription, DNA-dependent; chromatin modification | |
| ATAD2 | regulation of transcription, DNA-dependent | |
| ATE1 | protein arginylation | |
| ATF5 | negative regulation of astrocyte differentiation; negative regulation of neurogenesis; anti-apoptosis; regulation of transcription from RNA polymerase II promoter | |
| ATF6 | response to stress; protein folding; response to unfolded protein; activation of signaling protein activity involved in unfolded protein response; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; endoplasmic reticulum unfolded protein response; signal transduction | |
| ATF7IP | regulation of RNA polymerase II transcriptional preinitiation complex assembly; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; interspecies interaction between organisms; negative regulation of transcription from RNA polymerase II promoter; DNA methylation | |
| ATF7IP2 | regulation of transcription, DNA-dependent | |
| ATG16L1 | protein homooligomerization; autophagic vacuole assembly; protein transport; autophagy | |
| ATG16L2 | protein transport; autophagy | |
| ATG2A | - | |
| ATG2B | - | |
| ATG4A | autophagy; proteolysis; protein transport | |
| ATG7 | response to starvation; cardiac muscle cell development; negative regulation of apoptotic process; protein modification by small protein conjugation; positive regulation of protein modification process; regulation of protein ubiquitination; neuron projection development; protein catabolic process; neurological system process; cerebral cortex development; pyramidal neuron development; liver development; protein modification process; protein lipidation; cellular amino acid metabolic process; autophagy; cellular membrane fusion; organelle organization; adult walking behavior; post-embryonic development; protein transport; cerebellar Purkinje cell layer development; central nervous system neuron axonogenesis | |
| ATHL1 | carbohydrate metabolic process | |
| ATIC | purine base metabolic process; nucleobase-containing compound metabolic process; purine nucleotide biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; organ regeneration; small molecule metabolic process; nucleobase-containing small molecule metabolic process | |
| ATL1 | axonogenesis; protein homooligomerization; cell death; GTP catabolic process; endoplasmic reticulum organization | |
| ATL2 | GTP catabolic process; ER to Golgi vesicle-mediated transport; endoplasmic reticulum organization; Golgi organization; protein homooligomerization | |
| ATM | cell cycle checkpoint; double-strand break repair via homologous recombination; response to hypoxia; somitogenesis; pre-B cell allelic exclusion; DNA repair; double-strand break repair; DNA damage response, signal transduction resulting in induction of apoptosis; cell death; heart development; brain development; female gamete generation; signal transduction; reciprocal meiotic recombination; mitotic cell cycle spindle assembly checkpoint; cell cycle arrest; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; DNA damage induced protein phosphorylation; response to DNA damage stimulus; peptidyl-serine phosphorylation; response to ionizing radiation; replicative senescence; cellular response to gamma radiation; histone mRNA catabolic process; regulation of cell cycle; protein autophosphorylation; positive regulation of neuron apoptosis; positive regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of apoptotic process; positi | |
| ATN1 | neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; central nervous system development; cell death; toxin metabolic process; cell migration; maintenance of cell polarity; regulation of neuron differentiation | |
| ATOH1 | apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation; positive regulation of auditory receptor cell differentiation; auditory receptor cell fate determination; auditory receptor cell fate specification; inner ear morphogenesis; cerebral cortex development; central nervous system development; axon guidance; multicellular organismal development; neuron migration; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; brain development | |
| ATP10A | transmembrane transport; cation transport; phospholipid translocation; regulation of cell shape; ion transmembrane transport | |
| ATP10B | phospholipid translocation; cation transport | |
| ATP10D | ion transmembrane transport; cation transport; phospholipid translocation; transmembrane transport | |
| ATP11A | cation transport; phospholipid translocation | |
| ATP11B | cation transport; transmembrane transport; phospholipid translocation; ion transmembrane transport; aminophospholipid transport; ion transport | |
| ATP11C | cation transport; transmembrane transport; phospholipid translocation; ion transmembrane transport | |
| ATP12A | transmembrane transport; ion transmembrane transport; proton transport; potassium ion transport; ATP biosynthetic process | |
| ATP13A2 | cation transport | |
| ATP13A3 | cation transport | |
| ATP13A4 | cation transport; ATP biosynthetic process | |
| ATP13A5 | ATP biosynthetic process; cation transport | |
| ATP1A2 | transmembrane transport; reduction of cytosolic calcium ion concentration; negative regulation of striated muscle contraction; negative regulation of heart contraction; locomotion; ion transmembrane transport; regulation of vasoconstriction; visual learning; adult locomotory behavior; regulation of blood pressure; regulation of striated muscle contraction; regulation of smooth muscle contraction; sodium ion transport; neurotransmitter uptake; regulation of the force of heart contraction; regulation of respiratory gaseous exchange by neurological system process; ATP biosynthetic process; potassium ion transport; ATP hydrolysis coupled proton transport | |
| ATP1A3 | ion transmembrane transport; transmembrane transport; response to drug; ionotropic glutamate receptor signaling pathway; visual learning; adult locomotory behavior; memory; sodium ion transport; potassium ion transport; ATP biosynthetic process | |
| ATP1A4 | regulation of cellular pH; transmembrane transport; ion transmembrane transport; sperm motility; sodium ion transport; potassium ion transport; ATP biosynthetic process; ATP hydrolysis coupled proton transport | |
| ATP1B1 | sodium ion transport; transmembrane transport; leukocyte migration; ion transmembrane transport; blood coagulation; potassium ion transport; transport; ATP biosynthetic process; response to hypoxia | |
| ATP1B4 | transport; ATP metabolic process; monovalent inorganic cation transport; sodium ion transport; potassium ion transport; regulation of transcription, DNA-dependent | |
| ATP2A1 | positive regulation of fast-twitch skeletal muscle fiber contraction; elevation of endoplasmic reticulum calcium ion concentration; reduction of endoplasmic reticulum calcium ion concentration; ion transmembrane transport; response to endoplasmic reticulum stress; negative regulation of striated muscle contraction; elevation of mitochondrial calcium ion concentration; maintenance of mitochondrion location; apoptosis in response to endoplasmic reticulum stress; calcium ion import; relaxation of skeletal muscle; transmembrane transport; blood coagulation; apoptotic mitochondrial changes; ATP catabolic process; ATP biosynthetic process; calcium ion transport; regulation of striated muscle contraction; cation transport | |
| ATP2A2 | blood coagulation; sarcoplasmic reticulum calcium ion transport; transmembrane transport; ion transmembrane transport; epidermis development; cell adhesion; cation transport; transport; ATP biosynthetic process | |
| ATP2A3 | ATP biosynthetic process; transport; cation transport; calcium ion transport; blood coagulation; ion transmembrane transport; transmembrane transport | |
| ATP2B1 | cation transport; blood coagulation; ion transmembrane transport; transmembrane transport; calcium ion transmembrane transport; transport; ATP biosynthetic process | |
| ATP2B2 | brain development; inner ear morphogenesis; serotonin metabolic process; locomotion; ion transmembrane transport; neuron differentiation; cerebellar granule cell differentiation; cerebellar Purkinje cell differentiation; cerebellar Purkinje cell layer morphogenesis; cerebellum development; regulation of cell size; locomotory behavior; sensory perception of sound; blood coagulation; lactation; organelle organization; calcium ion transport; cation transport; transport; ATP biosynthetic process; ATP catabolic process; neural retina development; cell morphogenesis; otolith mineralization; cGMP metabolic process; regulation of synaptic plasticity; synapse organization; neuromuscular process controlling balance; detection of mechanical stimulus involved in sensory perception of sound; cytosolic calcium ion homeostasis; positive regulation of calcium ion transport; transmembrane transport; auditory receptor cell stereocilium organization; inner ear receptor cell differentiation; calcium ion transmembrane transport; | |
| ATP2B3 | ion transmembrane transport; blood coagulation; cation transport; transport; ATP biosynthetic process; transmembrane transport; calcium ion transmembrane transport | |
| ATP2B4 | transport; neural retina development; ATP biosynthetic process; cation transport; blood coagulation; ion transmembrane transport; transmembrane transport; calcium ion transmembrane transport | |
| ATP2C1 | transmembrane transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; cation transport; ion transmembrane transport; Golgi calcium ion transport; Golgi calcium ion homeostasis; actin cytoskeleton reorganization; cellular manganese ion homeostasis; calcium-dependent cell-cell adhesion; epidermis development; signal transduction; cellular calcium ion homeostasis; manganese ion transport; calcium ion transport; ATP biosynthetic process | |
| ATP5B | ADP biosynthetic process; angiogenesis; generation of precursor metabolites and energy; ATP catabolic process; regulation of intracellular pH; small molecule metabolic process; mitochondrial ATP synthesis coupled proton transport; respiratory electron transport chain; proton transport; ATP hydrolysis coupled proton transport; negative regulation of cell adhesion involved in substrate-bound cell migration; receptor-mediated endocytosis; ion transport; transport; ATP biosynthetic process; lipid metabolic process | |
| ATP5C1 | proton transport; respiratory electron transport chain; ATP biosynthetic process; mitochondrial ATP synthesis coupled proton transport; ion transport; oxidative phosphorylation; ATP catabolic process; small molecule metabolic process | |
| ATP5G2 | ATP hydrolysis coupled proton transport; ATP synthesis coupled proton transport; ion transport; transport | |
| ATP5G3 | transport; ion transport; aging; ATP synthesis coupled proton transport; ATP hydrolysis coupled proton transport; response to ethanol | |
| ATP5J | ATP catabolic process; small molecule metabolic process; transport; ion transport; respiratory electron transport chain; mitochondrial ATP synthesis coupled proton transport | |
| ATP5S | ion transport; ATP biosynthetic process; proton transport | |
| ATP5SL | - | |
| ATP6AP1 | ATP hydrolysis coupled proton transport; ion transport; aging; cell death; proton transport | |
| ATP6V0A1 | transmembrane transport; transferrin transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; ion transport | |
| ATP6V0A2 | cellular iron ion homeostasis; ion transport; immune response; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; transferrin transport; transmembrane transport | |
| ATP6V0A4 | regulation of pH; ossification; ion transport; cellular iron ion homeostasis; transmembrane transport; transferrin transport; proton transport; ATP hydrolysis coupled proton transport; excretion; insulin receptor signaling pathway; sensory perception of sound | |
| ATP6V0B | transferrin transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; transmembrane transport; proton transport; ion transport | |
| ATP6V0C | ion transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; interspecies interaction between organisms; transmembrane transport | |
| ATP6V0D1 | transmembrane transport; brain development; ion transmembrane transport; transferrin transport; endoplasmic reticulum unfolded protein response; proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; activation of signaling protein activity involved in unfolded protein response; cellular iron ion homeostasis; ATP catabolic process | |
| ATP6V0D2 | transmembrane transport; transferrin transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; ion transport; cellular iron ion homeostasis | |
| ATP6V1B1 | calcium ion homeostasis; transmembrane transport; ATP metabolic process; inner ear morphogenesis; ossification; cellular iron ion homeostasis; regulation of pH; excretion; sensory perception of sound; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; ion transmembrane transport; pH reduction | |
| ATP6V1B2 | ATP metabolic process; transmembrane transport; proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; ion transport; transferrin transport | |
| ATP6V1C1 | ATP catabolic process; transmembrane transport; ion transmembrane transport; transferrin transport; proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; transport | |
| ATP6V1C2 | transmembrane transport; ion transmembrane transport; transferrin transport; proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; ATP catabolic process | |
| ATP6V1E1 | ion transport; cellular iron ion homeostasis; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; transmembrane transport; insulin receptor signaling pathway | |
| ATP6V1E2 | ion transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; transmembrane transport | |
| ATP6V1G1 | transmembrane transport; ion transmembrane transport; transferrin transport; cellular iron ion homeostasis; proton transport; insulin receptor signaling pathway | |
| ATP7A | neuroprotection; extracellular matrix organization; pigmentation; positive regulation of catalytic activity; serotonin metabolic process; norepinephrine biosynthetic process; dopamine metabolic process; norepinephrine metabolic process; epinephrine metabolic process; T-helper cell differentiation; ion transmembrane transport; hair follicle morphogenesis; collagen fibril organization; hindlimb morphogenesis; skin development; ATP metabolic process; elastic fiber assembly; lung alveolus development; negative regulation of metalloenzyme activity; positive regulation of metalloenzyme activity; neuron projection morphogenesis; dendrite morphogenesis; cartilage development; positive regulation of oxidoreductase activity; elastin biosynthetic process; transmembrane transport; copper ion export; central nervous system neuron development; blood vessel development; in utero embryonic development; release of cytochrome c from mitochondria; blood vessel remodeling; regulation of oxidative phosphorylation; ATP catabolic p | |
| ATP7B | copper ion export; transmembrane transport; sequestering of calcium ion; response to copper ion; ion transmembrane transport; cellular copper ion homeostasis; metal ion transport; intracellular copper ion transport; copper ion import; lactation; cellular zinc ion homeostasis; copper ion transport; ATP biosynthetic process; ATP catabolic process | |
| ATP8A1 | aminophospholipid transport; ion transmembrane transport; phospholipid translocation; transmembrane transport; cation transport | |
| ATP8A2 | phospholipid transport; negative regulation of cell proliferation; cation transport | |
| ATP8B1 | bile acid metabolic process; cation transport; ATP catabolic process; bile acid and bile salt transport; ion transmembrane transport; phospholipid translocation; negative regulation of transcription, DNA-dependent; transmembrane transport | |
| ATP8B2 | phospholipid transport; cation transport; ion transmembrane transport; ATP catabolic process; transmembrane transport | |
| ATP8B4 | phospholipid transport; cation transport | |
| ATP9A | cation transport; phospholipid translocation | |
| ATP9B | cation transport; aminophospholipid transport; phospholipid translocation; establishment of protein localization in Golgi | |
| ATR | protein autophosphorylation; cellular response to gamma radiation; replicative senescence; positive regulation of DNA damage response, signal transduction by p53 class mediator; regulation of protein binding; cellular response to UV; peptidyl-serine phosphorylation; negative regulation of DNA replication; multicellular organismal development; response to DNA damage stimulus; protein phosphorylation; DNA repair; DNA replication; DNA damage checkpoint; cell cycle checkpoint; cell cycle | |
| ATRIP | cell cycle checkpoint; DNA damage checkpoint; DNA replication; DNA repair | |
| ATRN | inflammatory response; response to oxidative stress; regulation of multicellular organism growth; pigmentation | |
| ATRNL1 | G-protein coupled receptor signaling pathway | |
| ATRX | regulation of transcription, DNA-dependent; DNA duplex unwinding; forebrain development; DNA recombination; DNA methylation; DNA repair | |
| ATXN1 | RNA processing; cell death; adult locomotory behavior; visual learning; negative regulation of phosphorylation; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nuclear export; regulation of excitatory postsynaptic membrane potential | |
| ATXN2 | regulation of translation; cell death; RNA metabolic process; cytoplasmic mRNA processing body assembly; stress granule assembly; negative regulation of multicellular organism growth; neuron projection morphogenesis; homeostasis of number of cells; RNA transport; neuromuscular process; cerebellar Purkinje cell differentiation | |
| ATXN2L | - | |
| ATXN7L2 | - | |
| ATXN7L3 | positive regulation of transcription, DNA-dependent; histone deubiquitination; chromatin modification | |
| AUH | small molecule metabolic process; cellular nitrogen compound metabolic process; branched chain family amino acid catabolic process; mRNA catabolic process | |
| AUP1 | - | |
| AURKA | response to estradiol stimulus; regulation of protein stability; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell projection organization; mitosis; spindle organization; positive regulation of mitosis; protein phosphorylation; mitotic cell cycle; cell division; phosphatidylinositol-mediated signaling; protein autophosphorylation; regulation of centrosome cycle; cell cycle | |
| AURKAIP1 | positive regulation of proteolysis; negative regulation of mitosis | |
| AUTS2 | - | |
| AVEN | apoptotic process; anti-apoptosis | |
| AVIL | nervous system development; positive regulation of neuron projection development; actin filament capping; cilium morphogenesis; cytoskeleton organization; response to stress | |
| AVL9 | - | |
| AVPI1 | activation of MAPK activity; cell cycle | |
| AVPR1A | positive regulation of glutamate secretion; myotube differentiation; calcium-mediated signaling; telencephalon development; positive regulation of cell growth; positive regulation of prostaglandin biosynthetic process; positive regulation of cellular pH reduction; social behavior; positive regulation of renal sodium excretion; response to stress; cellular response to water deprivation; maternal behavior; sperm ejaculation; penile erection; positive regulation of vasoconstriction; response to corticosterone stimulus; negative regulation of transmission of nerve impulse; response to inorganic substance; regulation of systemic arterial blood pressure by vasopressin; maternal aggressive behavior; positive regulation of systemic arterial blood pressure; generation of precursor metabolites and energy; G-protein coupled receptor signaling pathway; activation of phospholipase C activity; elevation of cytosolic calcium ion concentration; negative regulation of female receptivity; grooming behavior; blood circulation; | |
| AVPR1B | activation of phospholipase C activity; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor signaling pathway; regulation of systemic arterial blood pressure by vasopressin; response to stress; positive regulation of heart rate; positive regulation of glutamate secretion; positive regulation of cellular pH reduction; hyperosmotic salinity response; positive regulation of blood pressure; elevation of cytosolic calcium ion concentration | |
| AVPR2 | interferon-gamma production; transmembrane transport; negative regulation of renal sodium excretion; negative regulation of urine volume; response to cytokine stimulus; telencephalon development; positive regulation of gene expression; hemostasis; excretion; positive regulation of cell proliferation; I-kappaB kinase/NF-kappaB cascade; activation of adenylate cyclase activity; G-protein signaling, coupled to cAMP nucleotide second messenger; water transport; positive regulation of systemic arterial blood pressure | |
| AWAT1 | lipid biosynthetic process | |
| AXDND1 | - | |
| AXIN1 | cellular response to organic cyclic compound; protein polyubiquitination; in utero embryonic development; optic placode formation; positive regulation of protein phosphorylation; nucleocytoplasmic transport; apoptotic process; signal transduction; activation of JUN kinase activity; olfactory placode formation; tail morphogenesis; negative regulation of transcription elongation from RNA polymerase II promoter; erythrocyte homeostasis; positive regulation of peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; activation of protein kinase activity; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of protein ubiquitination; cytoplasmic microtubule organization; regulation of catenin import into nucleus; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway involve | |
| AXL | secretion by cell; erythrocyte homeostasis; substrate adhesion-dependent cell spreading; ovulation cycle; apoptotic cell clearance; protein kinase B signaling cascade; negative regulation of neuron apoptosis; innate immune response; negative regulation of lymphocyte activation; vagina development; natural killer cell differentiation; negative regulation of tumor necrosis factor production; cellular response to extracellular stimulus; platelet activation; cell differentiation; forebrain cell migration; spermatogenesis; enzyme linked receptor protein signaling pathway; signal transduction; inflammatory response; blood vessel remodeling; neuron migration | |
| AZIN2 | spermatogenesis; agmatine biosynthetic process; small molecule metabolic process; positive regulation of catalytic activity; cellular nitrogen compound metabolic process; polyamine biosynthetic process; polyamine metabolic process; ornithine metabolic process | |
| AZU1 | induction of positive chemotaxis; defense response to Gram-negative bacterium; positive regulation of phagocytosis; positive regulation of fractalkine biosynthetic process; positive regulation of interleukin-1 beta biosynthetic process; macrophage chemotaxis; positive regulation of cell adhesion; positive regulation of MHC class II biosynthetic process; cellular extravasation; positive regulation of tumor necrosis factor biosynthetic process; monocyte activation; glial cell migration; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; inflammatory response; chemotaxis; anti-apoptosis; proteolysis; microglial cell activation; regulation of vascular permeability | |
| B2M | viral reproduction; immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; cytokine-mediated signaling pathway; interferon-gamma-mediated signaling pathway; regulation of immune response; regulation of defense response to virus by virus; antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I | |
| B3GALNT1 | oligosaccharide biosynthetic process; protein glycosylation | |
| B3GALT1 | protein glycosylation; oligosaccharide biosynthetic process; lipid glycosylation | |
| B3GALT5 | protein glycosylation | |
| B3GAT1 | metabolic process; carbohydrate metabolic process | |
| B3GAT2 | - | |
| B3GNT2 | protein glycosylation; cellular protein metabolic process; post-translational protein modification; O-glycan processing; sensory perception of smell; axon guidance | |
| B3GNT4 | protein glycosylation; O-glycan processing; post-translational protein modification; cellular protein metabolic process | |
| B3GNT8 | cellular protein metabolic process; post-translational protein modification; poly-N-acetyllactosamine biosynthetic process; O-glycan processing; protein glycosylation | |
| B4GALNT2 | lipid glycosylation; protein glycosylation; UDP-N-acetylgalactosamine metabolic process; negative regulation of cell-cell adhesion; UDP-N-acetylglucosamine metabolic process | |
| B4GALNT3 | - | |
| B4GALNT4 | - | |
| B4GALT1 | cellular protein metabolic process; post-translational protein modification; development of secondary sexual characteristics; branching morphogenesis of a tube; leukocyte migration; regulation of cellular component movement; regulation of acrosome reaction; positive regulation of epithelial cell proliferation involved in wound healing; positive regulation of apoptosis involved in mammary gland involution; angiogenesis involved in wound healing; extracellular matrix organization; mammary gland development; epithelial cell development; acute inflammatory response; carbohydrate metabolic process; lactose biosynthetic process; galactose metabolic process; protein glycosylation; cell adhesion; binding of sperm to zona pellucida; penetration of zona pellucida; negative regulation of cell proliferation; oligosaccharide biosynthetic process; protein N-linked glycosylation via asparagine | |
| B4GALT2 | post-translational protein modification; carbohydrate metabolic process; protein N-linked glycosylation via asparagine; cellular protein metabolic process | |
| B4GALT3 | cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; carbohydrate metabolic process | |
| B4GALT6 | protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process; carbohydrate metabolic process | |
| B4GALT7 | carbohydrate metabolic process; glycosaminoglycan biosynthetic process; proteoglycan metabolic process; protein modification process; fibril organization; negative regulation of fibroblast proliferation | |
| B9D2 | M phase of mitotic cell cycle; cilium assembly; mitotic cell cycle; cell projection organization; mitotic prometaphase | |
| BAALC | - | |
| BAAT | taurine metabolic process; small molecule metabolic process; organ regeneration; bile acid and bile salt transport; bile acid metabolic process; bile acid biosynthetic process; fatty acid metabolic process; liver development; bile acid conjugation; glycine metabolic process; acyl-CoA metabolic process; lipid metabolic process | |
| BACE1 | membrane protein ectodomain proteolysis; proteolysis; beta-amyloid metabolic process | |
| BACH1 | regulation of transcription involved in G1/S phase of mitotic cell cycle; regulation of transcription involved in G2/M-phase of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to hypoxia | |
| BACH2 | - | |
| BAG1 | response to nicotine; chaperone cofactor-dependent protein refolding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron apoptosis; response to drug; neuron differentiation; response to lithium ion; cell surface receptor signaling pathway; response to stress; anti-apoptosis | |
| BAG2 | protein folding; protein metabolic process | |
| BAG3 | anti-apoptosis; brain development; spinal cord development; protein folding | |
| BAG4 | cellular response to tumor necrosis factor; protein folding; anti-apoptosis | |
| BAG5 | negative regulation of protein ubiquitination; protein folding; negative regulation of ubiquitin-protein ligase activity; negative regulation of protein refolding; neuron death; regulation of inclusion body assembly | |
| BAHD1 | heterochromatin assembly; negative regulation of transcription, DNA-dependent; chromatin modification | |
| BAIAP2 | regulation of actin cytoskeleton organization; response to bacterium; insulin receptor signaling pathway; signal transduction; axonogenesis; filopodium assembly | |
| BAIAP2L1 | filopodium assembly; signal transduction; response to bacterium; positive regulation of actin filament polymerization; positive regulation of actin cytoskeleton reorganization | |
| BAIAP3 | neurotransmitter secretion; G-protein coupled receptor signaling pathway | |
| BANK1 | B cell activation | |
| BAP1 | protein deubiquitination; ubiquitin-dependent protein catabolic process; negative regulation of cell proliferation; chromatin modification; monoubiquitinated histone H2A deubiquitination; regulation of cell cycle; protein K48-linked deubiquitination; regulation of cell growth; protein modification process; proteolysis | |
| BARD1 | DNA repair; response to DNA damage stimulus; cell cycle arrest; spermatogenesis; protein ubiquitination; negative regulation of mRNA 3'-end processing; regulation of phosphorylation; positive regulation of apoptotic process; negative regulation of apoptotic process; positive regulation of protein catabolic process; negative regulation of protein export from nucleus; protein K6-linked ubiquitination; tissue homeostasis | |
| BARHL2 | cell fate determination; regulation of transcription from RNA polymerase II promoter; nervous system development; neuron differentiation; regulation of axon extension; positive regulation of translation; neuron migration | |
| BARX2 | positive regulation of transcription from RNA polymerase II promoter; catagen; myotube differentiation; cartilage condensation; negative regulation of transcription from RNA polymerase II promoter | |
| BATF | regulation of transcription, DNA-dependent | |
| BAZ1A | chromatin remodeling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; DNA-dependent DNA replication | |
| BAZ1B | ATP-dependent chromatin remodeling; heart morphogenesis; double-strand break repair; chromatin assembly or disassembly; nucleosome disassembly; transcription, DNA-dependent; chromatin-mediated maintenance of transcription; regulation of transcription, DNA-dependent; response to DNA damage stimulus; histone phosphorylation; DNA replication-dependent nucleosome disassembly; regulation of gene expression, epigenetic | |
| BAZ2B | regulation of transcription, DNA-dependent; transcription, DNA-dependent | |
| BBOX1 | small molecule metabolic process; carnitine biosynthetic process; cellular nitrogen compound metabolic process | |
| BBS10 | chaperone-mediated protein complex assembly; response to stimulus; photoreceptor cell maintenance; cellular protein metabolic process; nonmotile primary cilium assembly; retina homeostasis | |
| BBS12 | cellular protein metabolic process; chaperone-mediated protein complex assembly | |
| BBS2 | brain morphogenesis; photoreceptor cell maintenance; fat cell differentiation; Golgi to plasma membrane protein transport; negative regulation of multicellular organism growth; protein localization to organelle; leptin-mediated signaling pathway; melanosome transport; negative regulation of appetite; adult behavior; cerebral cortex development; hippocampus development; striatum development; protein localization; sperm axoneme assembly; response to stimulus; cilium morphogenesis; regulation of cilium beat frequency involved in ciliary motility | |
| BBS4 | adult behavior; regulation of cilium beat frequency involved in ciliary motility; nonmotile primary cilium assembly; microtubule anchoring at centrosome; protein localization to organelle; leptin-mediated signaling pathway; cell cycle cytokinesis; regulation of cytokinesis; melanosome transport; negative regulation of appetite; intracellular transport; cilium assembly; fat cell differentiation; photoreceptor cell maintenance; microtubule cytoskeleton organization; positive regulation of flagellum assembly; retinal rod cell development; cilium morphogenesis; convergent extension involved in gastrulation; pigment granule aggregation in cell center; maintenance of protein location in nucleus; centrosome organization; response to stimulus; sensory processing; brain morphogenesis; hippocampus development; cerebral cortex development; neural tube closure; retina homeostasis; heart looping; spermatid development; sensory perception of smell; dendrite development; regulation of lipid metabolic process; striatum devel | |
| BBS7 | determination of left/right symmetry; heart looping; visual perception; cilium morphogenesis; pigment granule aggregation in cell center; melanosome transport; fat cell differentiation; response to stimulus; digestive tract morphogenesis | |
| BCAM | cell adhesion; cell-matrix adhesion; signal transduction | |
| BCAN | cell adhesion; hippocampus development; regulation of neuronal synaptic plasticity | |
| BCAP29 | intracellular protein transport; apoptotic process; vesicle-mediated transport | |
| BCAR3 | signal transduction; small GTPase mediated signal transduction; response to drug | |
| BCAS1 | - | |
| BCAS2 | RNA splicing, via transesterification reactions; mRNA processing; RNA splicing | |
| BCAS3 | - | |
| BCAS4 | - | |
| BCDIN3D | - | |
| BCHE | synaptic transmission, cholinergic; response to nutrient; metabolic process; choline metabolic process; response to drug; response to alkaloid; cocaine metabolic process; negative regulation of synaptic transmission; response to glucocorticoid stimulus; response to folic acid; learning | |
| BCKDHB | response to cAMP; branched chain family amino acid catabolic process; response to nutrient; cellular nitrogen compound metabolic process; small molecule metabolic process; response to glucocorticoid stimulus | |
| BCKDK | peptidyl-histidine phosphorylation; cellular amino acid catabolic process; branched chain family amino acid catabolic process; phosphorylation | |
| BCL11A | B cell differentiation; negative regulation of dendrite development; regulation of dendrite development; positive regulation of collateral sprouting; hemopoiesis; T cell differentiation; negative regulation of collateral sprouting; positive regulation of transcription from RNA polymerase II promoter; protein sumoylation; negative regulation of protein homooligomerization; negative regulation of neuron projection development; negative regulation of axon extension; positive regulation of neuron projection development; negative regulation of gene expression; regulation of transcription, DNA-dependent | |
| BCL11B | alpha-beta T cell differentiation; positive regulation of transcription from RNA polymerase II promoter; skin development; positive T cell selection; regulation of keratinocyte proliferation; keratinocyte development; epithelial cell morphogenesis; negative regulation of cell proliferation; regulation of lipid metabolic process; striatal medium spiny neuron differentiation; central nervous system neuron differentiation; post-embryonic camera-type eye development; T cell differentiation in thymus; negative regulation of apoptotic process; odontogenesis of dentin-containing tooth; axonogenesis; regulation of transcription, DNA-dependent; thymus development; T cell receptor V(D)J recombination | |
| BCL2L1 | positive regulation of apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptosis; innate immune response; positive regulation of anti-apoptosis; response to cycloheximide; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; cellular process regulating host cell cycle in response to virus; cellular response to amino acid stimulus; germ cell development; cellular response to alkaloid; cellular response to gamma radiation; mitotic cell cycle G2/M transition checkpoint; negative regulation of establishment of protein localization in plasma membrane; negative regulation of release of cytochrome c from mitochondria; negative regulation of intrinsic apoptotic signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; growth; cytokinesis; ovarian follicle development; in utero embryonic development; release of cytochrome c from mitochondria; apoptotic process; anti-apoptosis; spermat | |
| BCL2L11 | ear development; positive regulation of cell cycle; regulation of organ growth; nerve growth factor receptor signaling pathway; regulation of developmental pigmentation; spleen development; thymus development; post-embryonic organ morphogenesis; cellular process regulating host cell cycle in response to virus; positive regulation of release of cytochrome c from mitochondria; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of apoptotic process; male gonad development; apoptotic process; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; cell-matrix adhesion; in utero embryonic development; positive regulation of neuron apoptosis; spermatogenesis; myeloid cell homeostasis; kidney development; B cell apoptosis; induction of apoptosis by extracellular signals; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; post-embryonic development; mammary gland development; positive regulation o | |
| BCL2L12 | apoptotic process | |
| BCL2L13 | activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; regulation of apoptotic process | |
| BCL6B | negative regulation of transcription from RNA polymerase II promoter | |
| BCL7A | negative regulation of transcription, DNA-dependent | |
| BCL9 | regulation of transforming growth factor beta receptor signaling pathway; Wnt receptor signaling pathway | |
| BCL9L | positive regulation of epithelial to mesenchymal transition; regulation of transcription, DNA-dependent; regulation of cell morphogenesis; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter | |
| BCLAF1 | induction of apoptosis; positive regulation of apoptotic process; positive regulation of intrinsic apoptotic signaling pathway; regulation of DNA-dependent transcription in response to stress; negative regulation of transcription, DNA-dependent; positive regulation of transcription initiation, DNA-dependent; positive regulation of response to DNA damage stimulus | |
| BCO2 | retinal metabolic process; retinoic acid metabolic process; carotene metabolic process | |
| BCOR | heart development; chromatin modification; negative regulation of histone H3-K4 methylation; negative regulation of histone H3-K36 methylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of bone mineralization; histone H2A monoubiquitination; odontogenesis; negative regulation of transcription, DNA-dependent; palate development; specification of axis polarity; negative regulation of tooth mineralization | |
| BCORL1 | regulation of transcription, DNA-dependent; chromatin modification | |
| BCR | regulation of Rho protein signal transduction; inner ear morphogenesis; regulation of cell cycle; regulation of small GTPase mediated signal transduction; neuromuscular process controlling balance; positive regulation of phagocytosis; negative regulation of inflammatory response; positive regulation of GTPase activity; negative regulation of neutrophil degranulation; signal transduction; small GTPase mediated signal transduction; brain development; actin cytoskeleton organization; negative regulation of cell migration; response to lipopolysaccharide; protein phosphorylation | |
| BCS1L | mitochondrial respiratory chain complex III assembly; mitochondrial respiratory chain complex IV assembly; mitochondrial respiratory chain complex I assembly; mitochondrion organization | |
| BDKRB1 | elevation of cytosolic calcium ion concentration; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of blood pressure; response to lipopolysaccharide; negative regulation of cell growth; sensory perception of pain; cell migration; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; inflammatory response; positive regulation of leukocyte migration; negative regulation of protein phosphorylation | |
| BDKRB2 | transmembrane receptor protein tyrosine kinase signaling pathway; arachidonic acid secretion; regulation of vascular permeability; regulation of vasoconstriction; blood circulation; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; inflammatory response; smooth muscle contraction; cell surface receptor signaling pathway | |
| BDNF | dendrite development; inner ear development; regulation of synaptic plasticity; regulation of retinal cell programmed cell death; positive regulation of neuron differentiation; negative regulation of neuron apoptosis; fear response; response to drug; mechanoreceptor differentiation; nerve development; regulation of metabolic process; glutamate secretion; neuron recognition; feeding behavior; learning or memory; axon target recognition; axon guidance; negative regulation of neuroblast proliferation; nervous system development; anti-apoptosis; ureteric bud development | |
| BDP1 | transcription from RNA polymerase III promoter; gene expression; regulation of transcription, DNA-dependent | |
| BECN1 | cellular defense response; autophagic vacuole assembly; cytokinesis; autophagy; anti-apoptosis; negative regulation of cell proliferation; response to virus; positive regulation of macroautophagy; cell cycle | |
| BEND2 | - | |
| BEND3 | - | |
| BEND5 | - | |
| BEND6 | - | |
| BEST1 | ion transport; chloride transport; visual perception; transepithelial chloride transport; response to stimulus | |
| BEST2 | ion transport; chloride transport; sensory perception of smell; membrane depolarization | |
| BEST3 | ion transmembrane transport; negative regulation of ion transport | |
| BEST4 | ion transport | |
| BEX5 | - | |
| BFSP2 | lens fiber cell development; response to stimulus; cell maturation; intermediate filament cytoskeleton organization; visual perception | |
| BHLHE40 | circadian regulation of gene expression; regulation of neuronal synaptic plasticity; negative regulation of sequence-specific DNA binding transcription factor activity; entrainment of circadian clock by photoperiod; response to light stimulus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| BHLHE41 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; circadian rhythm; cell proliferation; organ morphogenesis; negative regulation of myotube differentiation; negative regulation of transcription by competitive promoter binding; cell differentiation | |
| BHMT | sulfur amino acid metabolic process; protein methylation; methionine biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process; regulation of homocysteine metabolic process | |
| BHMT2 | methionine biosynthetic process | |
| BICC1 | multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway | |
| BICD2 | microtubule anchoring at microtubule organizing center; transport; minus-end-directed organelle transport along microtubule | |
| BIN1 | positive regulation of endocytosis; interspecies interaction between organisms; multicellular organismal development; cell proliferation; muscle cell differentiation; positive regulation of GTPase activity | |
| BIN2 | - | |
| BIRC2 | regulation of RIG-I signaling pathway; regulation of cysteine-type endopeptidase activity; NIK/NF-kappaB cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; regulation of innate immune response; regulation of cell differentiation; regulation of inflammatory response; regulation of cell cycle; negative regulation of apoptotic process; regulation of cell proliferation; regulation of toll-like receptor signaling pathway; cell surface receptor signaling pathway; cellular component disassembly involved in apoptosis; anti-apoptosis; apoptotic process; placenta development; protein polyubiquitination; regulation of nucleotide-binding oligomerization domain containing signaling pathway | |
| BIRC3 | anti-apoptosis; regulation of cysteine-type endopeptidase activity; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of inflammatory response; regulation of innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; regulation of RIG-I signaling pathway; NIK/NF-kappaB cascade; regulation of toll-like receptor signaling pathway; cell surface receptor signaling pathway | |
| BIRC5 | G2/M transition of mitotic cell cycle; establishment of chromosome localization; positive regulation of mitotic cell cycle; cell division; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cytokinesis; protein phosphorylation; anti-apoptosis; chromosome segregation; positive regulation of cell proliferation; protein complex localization; positive regulation of exit from mitosis; spindle checkpoint; regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of transcription, DNA-dependent; mitosis | |
| BLK | B cell receptor signaling pathway; positive regulation of insulin secretion; intracellular protein kinase cascade | |
| BLM | G2 phase of mitotic cell cycle; telomere maintenance; double-strand break repair via homologous recombination; DNA strand renaturation; ATP catabolic process; DNA replication; DNA repair; DNA recombination; response to DNA damage stimulus; response to X-ray; replication fork processing; G2/M transition DNA damage checkpoint; regulation of cyclin-dependent protein kinase activity; cellular metabolic process; positive regulation of transcription, DNA-dependent; negative regulation of DNA recombination; negative regulation of mitotic recombination; alpha-beta T cell differentiation; positive regulation of alpha-beta T cell proliferation; replication fork protection; regulation of binding; protein oligomerization; negative regulation of cell division; chromosome organization | |
| BLNK | inflammatory response; intracellular signal transduction; B cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; humoral immune response | |
| BLOC1S6 | - | |
| BLZF1 | regulation of cell growth; Golgi to plasma membrane protein transport; vesicle-mediated transport; protein transport; cell proliferation; Golgi organization; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| BMF | positive regulation of protein homooligomerization; regulation of apoptotic process; positive regulation of release of cytochrome c from mitochondria; apoptotic process; activation of pro-apoptotic gene products; induction of apoptosis by intracellular signals | |
| BMP1 | positive regulation of cartilage development; small molecule metabolic process; cell differentiation; multicellular organismal development; lipoprotein metabolic process; lipid metabolic process; proteolysis; ossification; cartilage condensation; skeletal system development | |
| BMP10 | Notch signaling pathway; atrial cardiac muscle tissue morphogenesis; positive regulation of transcription, DNA-dependent; sarcomere organization; growth; ventricular cardiac muscle tissue morphogenesis; ventricular cardiac muscle cell development; cardiac muscle cell proliferation; positive regulation of cardiac muscle cell proliferation; heart trabecula formation; pathway-restricted SMAD protein phosphorylation; activin receptor signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; multicellular organismal development; adult heart development; negative regulation of endothelial cell migration; positive regulation of cardiac muscle hypertrophy; negative regulation of cardiac muscle hypertrophy; BMP signaling pathway; negative regulation of cell migration; negative regulation of cell growth | |
| BMP15 | granulosa cell development; female gamete generation; ovarian follicle development | |
| BMP2 | positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cell cycle; positive regulation of ossification; positive regulation of osteoblast differentiation; positive regulation of neuron differentiation; positive regulation of fat cell differentiation; cell fate commitment; cardiac muscle tissue morphogenesis; ovulation cycle; regulation of odontogenesis of dentin-containing tooth; positive regulation of odontogenesis; odontogenesis of dentin-containing tooth; growth; positive regulation of astrocyte differentiation; mesenchymal cell differentiation; inner ear development; positive regulation of neurogenesis; oxidation-reduction process; pericardium development; corticotropin hormone secreting cell differentiation; thyroid-stimulating hormone-secreting cell differentiation; cardiac epithelial to mesenchymal transition; pathway-r | |
| BMP2K | regulation of bone mineralization; regulation of catalytic activity | |
| BMP4 | positive regulation of cardiac muscle fiber development; positive chemotaxis; branching morphogenesis of a tube; smooth muscle tissue development; positive regulation of smooth muscle cell proliferation; intermediate mesodermal cell differentiation; lung alveolus development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of striated muscle tissue development; negative regulation of mitosis; negative regulation of cell cycle; positive regulation of ossification; positive regulation of osteoblast differentiation; negative regulation of myoblast differentiation; negative regulation of MAP kinase activity; steroid hormone mediated signaling pathway; negative regulation of apoptotic process; positive regulation of apoptotic process; odontogenesis; negative regulation of cell death; specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway; ne | |
| BMP5 | growth; cartilage development; male genitalia development; cell differentiation; pattern specification process; ossification; skeletal system development | |
| BMP6 | positive regulation of osteoblast differentiation; SMAD protein signal transduction; cartilage development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation; positive regulation of endothelial cell differentiation; growth; positive regulation of aldosterone biosynthetic process; male genitalia development; BMP signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; multicellular organismal development; immune response; inflammatory response; positive regulation of bone mineralization; endochondral ossification; positive regulation of endothelial cell proliferation; kidney development; eye development; skeletal system development | |
| BMP7 | anatomical structure formation involved in morphogenesis; embryonic skeletal joint morphogenesis; branching morphogenesis of a tube; mesenchymal cell differentiation; neuron projection morphogenesis; negative regulation of neurogenesis; cartilage development; positive regulation of osteoblast differentiation; embryonic camera-type eye morphogenesis; cell development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of mitosis; negative regulation of cell cycle; negative regulation of Notch signaling pathway; pathway-restricted SMAD protein phosphorylation; SMAD protein signal transduction; branching involved in salivary gland morphogenesis; mesenchyme development; negative regulation of cell death; negative regulation of prostatic bud formation; regulation of branching involved in prostate gland morphogenesis; monocyte aggregation; cellular response to hypoxia; neg | |
| BMPER | regulation of pathway-restricted SMAD protein phosphorylation; endothelial cell activation; blood vessel endothelial cell proliferation involved in sprouting angiogenesis; regulation of endothelial cell migration; positive regulation of ERK1 and ERK2 cascade; negative regulation of BMP signaling pathway; ureteric bud development | |
| BMPR1B | skeletal system development; positive regulation of osteoblast differentiation; positive regulation of cell differentiation; ovulation cycle; limb morphogenesis; BMP signaling pathway; positive regulation of bone mineralization; transmembrane receptor protein serine/threonine kinase signaling pathway; protein phosphorylation; eye development; ovarian cumulus expansion; cartilage condensation | |
| BMPR2 | positive regulation of BMP signaling pathway; vascular endothelial growth factor receptor signaling pathway; lung alveolus development; negative regulation of vasoconstriction; positive regulation of osteoblast differentiation; regulation of cell proliferation; retina development in camera-type eye; BMP signaling pathway; positive regulation of bone mineralization; negative regulation of cell growth; regulation of lung blood pressure; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of endothelial cell migration; anterior/posterior pattern specification; cellular response to starvation; brain development; transmembrane receptor protein serine/threonine kinase signaling pathway; transcription from RNA polymerase II promoter; negative regulation of systemic arterial blood pressure; positive regulation of endothelial cell proliferation; mesoderm formation; positive regulation of epithelial cell migration | |
| BMX | intracellular signal transduction; protein autophosphorylation; mesoderm development; signal transduction; cell adhesion; response to stress; apoptotic process; protein phosphorylation; cellular component disassembly involved in apoptosis | |
| BNC1 | epidermis development; positive regulation of cell proliferation; regulation of transcription, DNA-dependent | |
| BNC2 | regulation of transcription, DNA-dependent | |
| BNIP3L | induction of apoptosis; negative regulation of survival gene product expression; mitochondrial protein catabolic process; negative regulation of apoptotic process; interspecies interaction between organisms; defense response to virus | |
| BNIPL | apoptotic process; induction of apoptosis; negative regulation of cell proliferation; regulation of growth rate | |
| BOC | cell adhesion; muscle cell differentiation; positive regulation of myoblast differentiation; positive regulation of muscle cell differentiation | |
| BOK | oligodendrocyte differentiation; signal transduction by p53 class mediator resulting in induction of apoptosis; male gonad development; cell proliferation; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; apoptotic process; brain development | |
| BOLL | multicellular organismal development; regulation of translation; meiosis; spermatogenesis; cell differentiation; positive regulation of translational initiation | |
| BORA | regulation of mitosis; regulation of protein localization; regulation of mitotic spindle organization; cell division; cell cycle | |
| BORCS5 | - | |
| BPGM | carbohydrate metabolic process; glycolysis; respiratory gaseous exchange; erythrocyte development | |
| BPHL | response to toxin; cellular amino acid metabolic process | |
| BPIFA1 | innate immune response | |
| BPIFA3 | - | |
| BPIFB2 | - | |
| BPIFB4 | - | |
| BPIFB6 | - | |
| BPIFC | - | |
| BPTF | positive regulation of transcription, DNA-dependent; brain development; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; chromatin remodeling; regulation of transcription, DNA-dependent | |
| BRAF | protein phosphorylation; activation of MAPKK activity; anti-apoptosis; small GTPase mediated signal transduction; synaptic transmission; fibroblast growth factor receptor signaling pathway; organ morphogenesis; positive regulation of gene expression; negative regulation of apoptotic process; response to peptide hormone stimulus; negative regulation of neuron apoptosis; nerve growth factor receptor signaling pathway; response to cAMP; positive regulation of ERK1 and ERK2 cascade; positive regulation of peptidyl-serine phosphorylation | |
| BRAP | protein ubiquitination; negative regulation of signal transduction; Ras protein signal transduction; MAPK cascade | |
| BRAT1 | response to ionizing radiation | |
| BRCA1 | positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of centriole replication; positive regulation of histone H3-K4 methylation; negative regulation of histone H3-K4 methylation; negative regulation of histone H3-K9 methylation; positive regulation of histone H3-K9 methylation; protein autoubiquitination; positive regulation of histone H4-K20 methylation; positive regulation of cell cycle arrest; cellular response to indole-3-methanol; protein K6-linked ubiquitination; regulation of cell motility; positive regulation of histone H3-K9 acetylation; positive regulation of histone H4-K16 acetylation; substrate adhesion-dependent cell spreading; regulation of transcription from RNA polymerase III promoter; DNA damage response, signal transduction resulting in induction of apoptosis; response to nutrient; brain development; centrosome cycle; chromosome segregation; cell cycle; DNA damage response, signal transduction by p53 cl | |
| BRCA2 | response to estradiol stimulus; regulation of cytokinesis; cell cycle cytokinesis; negative regulation of mammary gland epithelial cell proliferation; multicellular organism growth; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; chordate embryonic development; histone H3 acetylation; histone H4 acetylation; positive regulation of transcription, DNA-dependent; positive regulation of mitotic cell cycle; replication fork protection; chromosome organization; centrosome duplication; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; mammary gland development; homologous chromosome orientation involved in meiotic metaphase I plate congression; double-strand break repair via homologous recombination; oocyte maturation; inner cell mass cell proliferation; DNA repair; nucleotide-excision repair; double-strand break repair; DNA recombination; cell cycle; regulation of S phase of mitotic cell cycle; male me | |
| BRD1 | chromatin modification; histone H3 acetylation | |
| BRD3 | - | |
| BRD4 | regulation of transcription involved in G1 phase of mitotic cell cycle; positive regulation of G2/M transition of mitotic cell cycle; histone H4-K12 acetylation; inner cell mass cell proliferation; protein phosphorylation; chromosome segregation; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of DNA binding; histone H3-K14 acetylation; interspecies interaction between organisms | |
| BRD7 | Wnt receptor signaling pathway; negative regulation of cell proliferation; cell cycle; positive regulation of histone acetylation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; negative regulation of G1/S transition of mitotic cell cycle | |
| BRD8 | regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; chromatin modification; cell surface receptor signaling pathway; regulation of growth; histone H2A acetylation; histone H4 acetylation; signal transduction | |
| BRDT | chromatin remodeling; regulation of transcription, DNA-dependent | |
| BRF2 | regulation of transcription, DNA-dependent; transcription from RNA polymerase III promoter; gene expression; transcription initiation, DNA-dependent | |
| BRICD5 | - | |
| BRINP1 | cell death; cell cycle arrest; negative regulation of cell cycle | |
| BRINP2 | nervous system development; negative regulation of cell cycle | |
| BRINP3 | negative regulation of cell cycle; nervous system development | |
| BRIP1 | double-strand break repair; nucleobase-containing compound metabolic process; DNA damage checkpoint; regulation of transcription from RNA polymerase II promoter | |
| BRIX1 | ribosome biogenesis | |
| BRMS1 | positive regulation of protein deacetylation; positive regulation of anoikis; negative regulation of transcription, DNA-dependent; negative regulation of NF-kappaB transcription factor activity; apoptotic process; negative regulation of anti-apoptosis | |
| BRPF1 | positive regulation of transcription, DNA-dependent; histone H3 acetylation; chromatin modification | |
| BRPF3 | blood coagulation; histone H3 acetylation; platelet activation; chromatin modification; platelet degranulation | |
| BRS3 | glucose metabolic process; regulation of blood pressure; adult feeding behavior; bombesin receptor signaling pathway | |
| BRSK1 | nervous system development; axonogenesis; response to DNA damage stimulus; response to UV; response to ionizing radiation; establishment of cell polarity; neuron differentiation; neurotransmitter secretion; cell cycle; G2/M transition DNA damage checkpoint; centrosome duplication; protein phosphorylation | |
| BRWD1 | regulation of transcription from RNA polymerase II promoter; cytoskeleton organization; regulation of cell shape | |
| BRWD3 | regulation of cell shape; cytoskeleton organization | |
| BSCL2 | cell death | |
| BSDC1 | - | |
| BSG | response to cAMP; pyruvate metabolic process; cell surface receptor signaling pathway; leukocyte migration; decidualization; response to mercury ion; small molecule metabolic process; response to peptide hormone stimulus; odontogenesis of dentin-containing tooth; lactate transmembrane transport; blood coagulation; embryo implantation | |
| BSN | synaptic transmission | |
| BSND | chloride transport | |
| BSPRY | calcium ion transport; ion transport | |
| BST1 | humoral immune response; multicellular organismal development | |
| BST2 | cell proliferation; defense response to virus; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; B cell activation; humoral immune response; signal transduction; cell-cell signaling; multicellular organismal development | |
| BTAF1 | negative regulation of transcription, DNA-dependent | |
| BTBD10 | - | |
| BTBD11 | - | |
| BTBD16 | - | |
| BTBD17 | - | |
| BTBD2 | - | |
| BTBD3 | - | |
| BTBD7 | - | |
| BTBD8 | - | |
| BTBD9 | cell adhesion | |
| BTF3L4 | - | |
| BTG3 | negative regulation of cell proliferation; negative regulation of mitotic cell cycle | |
| BTG4 | cell cycle arrest; negative regulation of mitotic cell cycle; neuron differentiation; negative regulation of cell proliferation | |
| BTN1A1 | negative regulation of cellular metabolic process; negative regulation of activated T cell proliferation; negative regulation of cytokine secretion | |
| BTN2A1 | lipid metabolic process | |
| BTN3A1 | lipid metabolic process | |
| BTN3A2 | - | |
| BTNL9 | - | |
| BTRC | mammary gland epithelial cell proliferation; protein destabilization; regulation of I-kappaB kinase/NF-kappaB cascade; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; positive regulation of circadian rhythm; negative regulation of sequence-specific DNA binding transcription factor activity; cellular response to organic cyclic compound; interspecies interaction between organisms; positive regulation of proteolysis; negative regulation of smoothened signaling pathway; regulation of proteasomal protein catabolic process; branching involved in mammary gland duct morphogenesis; regulation of cell cycle; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein ubiquitination; mitotic cell cycle; protein dephosphorylation; ubiquitin-dependent prot | |
| BUB1 | regulation of chromosome segregation; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; protein phosphorylation; apoptotic process; regulation of sister chromatid cohesion; mitotic cell cycle checkpoint; mitotic cell cycle spindle assembly checkpoint; cell proliferation; embryo development; interspecies interaction between organisms; cell division; spindle assembly checkpoint | |
| BUB1B | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell proliferation; mitotic metaphase/anaphase transition; mitotic cell cycle spindle assembly checkpoint; mitotic cell cycle checkpoint; M phase of mitotic cell cycle; protein localization to kinetochore; phosphatidylinositol-mediated signaling; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; spindle organization; cell cycle; apoptotic process; protein phosphorylation; mitotic cell cycle; mitotic prometaphase; mitosis; cell cycle checkpoint | |
| BVES | regulation of Rac GTPase activity; substrate adhesion-dependent cell spreading; positive regulation of locomotion; vesicle-mediated transport; epithelial cell-cell adhesion; regulation of Cdc42 GTPase activity; multicellular organismal development; muscle organ development; cell adhesion; regulation of cell shape; positive regulation of receptor recycling | |
| BYSL | ribosome biogenesis; female pregnancy; cell adhesion | |
| BZRAP1 | - | |
| C10orf10 | - | |
| C10orf120 | - | |
| C10orf2 | protein homooligomerization; protein hexamerization; cell death; DNA replication; transcription from mitochondrial promoter; DNA unwinding involved in replication; mitochondrial DNA replication | |
| C10orf35 | - | |
| C10orf76 | - | |
| C10orf82 | - | |
| C10orf88 | - | |
| C10orf90 | mitotic cell cycle G2/M transition DNA damage checkpoint; protein stabilization; response to DNA damage stimulus; response to UV; response to ionizing radiation; negative regulation of cell growth | |
| C11orf40 | - | |
| C11orf53 | - | |
| C11orf65 | - | |
| C11orf70 | - | |
| C11orf84 | - | |
| C11orf87 | - | |
| C12orf10 | pigmentation | |
| C12orf29 | - | |
| C12orf4 | - | |
| C12orf40 | - | |
| C12orf50 | - | |
| C12orf60 | - | |
| C12orf65 | translational termination | |
| C14orf105 | - | |
| C14orf159 | - | |
| C14orf180 | - | |
| C14orf2 | - | |
| C14orf28 | - | |
| C14orf37 | - | |
| C14orf39 | regulation of sequence-specific DNA binding transcription factor activity; multicellular organismal development | |
| C14orf79 | - | |
| C14orf93 | - | |
| C15orf32 | - | |
| C15orf39 | - | |
| C15orf40 | - | |
| C15orf54 | - | |
| C15orf59 | - | |
| C16orf45 | - | |
| C16orf46 | - | |
| C16orf59 | - | |
| C16orf62 | - | |
| C16orf71 | - | |
| C16orf78 | - | |
| C16orf91 | - | |
| C17orf47 | - | |
| C17orf53 | - | |
| C17orf74 | - | |
| C17orf80 | - | |
| C17orf98 | - | |
| C18orf25 | - | |
| C19orf18 | - | |
| C19orf44 | - | |
| C19orf45 | - | |
| C19orf53 | - | |
| C19orf70 | - | |
| C19orf73 | - | |
| C1D | maturation of 5.8S rRNA; negative regulation of transcription, DNA-dependent; apoptotic process | |
| C1GALT1C1 | post-translational protein modification; cellular protein metabolic process; O-glycan processing | |
| C1orf100 | - | |
| C1orf101 | - | |
| C1orf106 | - | |
| C1orf111 | - | |
| C1orf116 | - | |
| C1orf127 | - | |
| C1orf131 | - | |
| C1orf141 | - | |
| C1orf168 | - | |
| C1orf189 | - | |
| C1orf21 | - | |
| C1orf216 | - | |
| C1orf222 | - | |
| C1orf50 | - | |
| C1orf64 | - | |
| C1orf87 | - | |
| C1orf95 | - | |
| C1QA | complement activation; complement activation, classical pathway; cell-cell signaling; innate immune response | |
| C1QB | response to glucocorticoid stimulus; innate immune response; response to organic substance; aging; complement activation; complement activation, classical pathway; brain development | |
| C1QBP | blood coagulation; immune response; blood coagulation, intrinsic pathway; interspecies interaction between organisms | |
| C1QC | immune response; complement activation; complement activation, classical pathway; negative regulation of granulocyte differentiation; innate immune response; negative regulation of macrophage differentiation | |
| C1QL3 | - | |
| C1QL4 | - | |
| C1QTNF1 | protein homooligomerization | |
| C1QTNF3 | negative regulation of gluconeogenesis | |
| C1QTNF4 | - | |
| C1QTNF6 | - | |
| C1S | proteolysis; complement activation; response to cAMP; complement activation, classical pathway; glial cell differentiation; innate immune response | |
| C20orf141 | - | |
| C20orf194 | - | |
| C20orf27 | - | |
| C20orf96 | - | |
| C21orf2 | regulation of cell shape; cytoskeleton organization | |
| C21orf33 | - | |
| C21orf91 | - | |
| C22orf29 | - | |
| C22orf31 | - | |
| C22orf42 | - | |
| C2CD2 | - | |
| C2CD2L | - | |
| C2CD3 | - | |
| C2CD4A | - | |
| C2CD5 | - | |
| C2orf15 | - | |
| C2orf16 | - | |
| C2orf40 | G1 to G0 transition; cyclin catabolic process; cellular senescence | |
| C2orf42 | - | |
| C2orf44 | - | |
| C2orf49 | embryonic morphogenesis | |
| C2orf54 | - | |
| C2orf57 | - | |
| C2orf66 | - | |
| C2orf70 | - | |
| C2orf76 | - | |
| C2orf83 | transport | |
| C3 | complement activation; regulation of immune response; positive regulation of phagocytosis; positive regulation of angiogenesis; innate immune response; positive regulation vascular endothelial growth factor production; G-protein coupled receptor signaling pathway; signal transduction; complement activation, classical pathway; positive regulation of type IIa hypersensitivity; positive regulation of activation of membrane attack complex; inflammatory response; immune response; complement activation, alternative pathway | |
| C3AR1 | chemotaxis; complement receptor mediated signaling pathway; positive regulation of neutrophil chemotaxis; inflammatory response; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; blood circulation; regulation of blood pressure; positive regulation vascular endothelial growth factor production; positive regulation of macrophage chemotaxis; positive regulation of cell migration; positive regulation of angiogenesis; tolerance induction to nonself antigen | |
| C3orf14 | - | |
| C3orf17 | - | |
| C3orf20 | - | |
| C3orf22 | - | |
| C3orf30 | - | |
| C3orf58 | - | |
| C3orf62 | - | |
| C3orf67 | - | |
| C3orf70 | - | |
| C4orf17 | - | |
| C4orf22 | - | |
| C4orf26 | - | |
| C5 | negative regulation of dopamine secretion; activation of MAPK activity; in utero embryonic development; leukocyte migration involved in inflammatory response; cellular calcium ion homeostasis; induction of apoptosis; chemotaxis; response to stress; inflammatory response; complement activation; complement activation, alternative pathway; complement activation, classical pathway; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; positive regulation vascular endothelial growth factor production; negative regulation of norepinephrine secretion; negative regulation of macrophage chemotaxis; positive regulation of chemokine secretion; positive regulation of chemotaxis; positive regulation of angiogenesis; innate immune response; glucose homeostasis; cytolysis | |
| C5AR2 | - | |
| C5orf15 | - | |
| C5orf22 | - | |
| C5orf28 | - | |
| C5orf42 | - | |
| C5orf51 | - | |
| C6 | innate immune response; cytolysis; complement activation, classical pathway; complement activation; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; positive regulation of activation of membrane attack complex; in utero embryonic development; positive regulation of angiogenesis | |
| C6orf106 | - | |
| C6orf118 | - | |
| C6orf201 | - | |
| C6orf203 | - | |
| C6orf58 | - | |
| C7orf25 | - | |
| C7orf34 | - | |
| C7orf43 | - | |
| C7orf50 | - | |
| C7orf62 | - | |
| C8A | complement activation, classical pathway; innate immune response; cytolysis; complement activation, alternative pathway; complement activation; immune response | |
| C8B | immune response; complement activation; complement activation, alternative pathway; complement activation, classical pathway; cytolysis; innate immune response | |
| C8orf31 | - | |
| C8orf33 | - | |
| C8orf34 | signal transduction | |
| C8orf44 | - | |
| C9 | hemolysis by symbiont of host erythrocytes; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; complement activation, alternative pathway; complement activation, classical pathway; blood coagulation; cytolysis; innate immune response | |
| C9orf116 | - | |
| C9orf131 | - | |
| C9orf135 | - | |
| C9orf3 | proteolysis; leukotriene biosynthetic process | |
| C9orf43 | - | |
| C9orf47 | - | |
| C9orf64 | - | |
| C9orf72 | cell death | |
| C9orf78 | - | |
| C9orf84 | - | |
| C9orf85 | - | |
| C9orf9 | - | |
| C9orf91 | - | |
| CA1 | one-carbon metabolic process | |
| CA10 | brain development | |
| CA11 | - | |
| CA12 | one-carbon metabolic process | |
| CA14 | - | |
| CA2 | morphogenesis of an epithelium; response to stress; one-carbon metabolic process; carbon dioxide transport; response to pH; response to organic substance; response to zinc ion; secretion; positive regulation of bone resorption; positive regulation of osteoclast differentiation; response to estrogen stimulus; odontogenesis of dentin-containing tooth; positive regulation of cellular pH reduction; kidney development | |
| CA3 | response to oxidative stress; one-carbon metabolic process | |
| CA5B | one-carbon metabolic process; metabolic process | |
| CA9 | secretion; one-carbon metabolic process; morphogenesis of an epithelium | |
| CAAP1 | apoptotic process | |
| CAB39 | protein heterooligomerization; regulation of fatty acid oxidation; insulin receptor signaling pathway; cell cycle arrest; positive regulation of protein phosphorylation | |
| CABIN1 | negative regulation of cell death; chromatin modification; cell surface receptor signaling pathway | |
| CABLES1 | nervous system development; blood coagulation; regulation of cell division; regulation of cell cycle | |
| CABP1 | negative regulation of catalytic activity | |
| CABP4 | visual perception; signal transduction; phototransduction; photoreceptor cell morphogenesis; retinal cone cell development; retinal bipolar neuron differentiation | |
| CABP7 | - | |
| CACFD1 | synaptic vesicle endocytosis | |
| CACHD1 | ion transport; calcium ion transport | |
| CACNA1D | small molecule metabolic process; axon guidance; transmembrane transport; regulation of insulin secretion; regulation of calcium ion transport via voltage-gated calcium channel activity; calcium ion transport; ion transport; energy reserve metabolic process | |
| CACNA1F | cellular calcium ion homeostasis; axon guidance; ion transport; regulation of calcium ion transport via voltage-gated calcium channel activity; transmembrane transport; retina development in camera-type eye; dendrite morphogenesis; detection of light stimulus involved in visual perception; response to stimulus; visual perception | |
| CACNA1S | striated muscle contraction; transmembrane transport; muscle cell development; regulation of calcium ion transport via voltage-gated calcium channel activity; skeletal muscle adaptation; neuromuscular junction development; myoblast fusion; axon guidance; endoplasmic reticulum organization; extraocular skeletal muscle development; muscle contraction; skeletal system development; calcium ion transport; ion transport | |
| CACNA2D1 | calcium ion transport; regulation of calcium ion transport via voltage-gated calcium channel activity; ion transport | |
| CACNA2D2 | energy reserve metabolic process; neuromuscular junction development; ion transport; rhythmic synaptic transmission; muscle fiber development; regulation of insulin secretion; regulation of multicellular organism growth; small molecule metabolic process; positive regulation of organ growth | |
| CACNB2 | ion transport; calcium ion transmembrane transport; regulation of calcium ion transport via voltage-gated calcium channel activity; visual perception; neuromuscular junction development; axon guidance; synaptic transmission; calcium ion transport; transport | |
| CACNG3 | ion transport; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; calcium ion transport; synaptic transmission; regulation of calcium ion transport via voltage-gated calcium channel activity | |
| CACNG4 | ion transport; transport; synaptic transmission; membrane depolarization; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; regulation of calcium ion transport via voltage-gated calcium channel activity | |
| CACNG5 | regulation of calcium ion transport via voltage-gated calcium channel activity; transport; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ion transmembrane transport | |
| CACNG8 | calcium ion transport; synaptic transmission; ion transport; regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | |
| CACUL1 | - | |
| CAD | response to amine stimulus; drug metabolic process; peptidyl-threonine phosphorylation; response to caffeine; organ regeneration; response to testosterone stimulus; small molecule metabolic process; pyrimidine nucleoside biosynthetic process; protein autophosphorylation; nucleobase-containing small molecule metabolic process; carbamoyl phosphate biosynthetic process; embryo development; female pregnancy; nitrogen compound metabolic process; glutamine catabolic process; glutamine metabolic process; cellular amino acid metabolic process; pyrimidine nucleotide biosynthetic process; 'de novo' pyrimidine base biosynthetic process; pyrimidine base metabolic process | |
| CADM1 | positive regulation of natural killer cell mediated cytotoxicity; positive regulation of cytokine secretion; activated T cell proliferation; detection of stimulus; cell-cell junction organization; susceptibility to natural killer cell mediated cytotoxicity; adherens junction organization; cell differentiation; T cell mediated cytotoxicity; apoptotic process; cell adhesion; homophilic cell adhesion; heterophilic cell-cell adhesion; multicellular organismal development; spermatogenesis; cell recognition; cell junction assembly | |
| CADPS | positive regulation of calcium ion-dependent exocytosis; synaptic vesicle priming; exocytosis; protein transport; vesicle organization; catecholamine secretion | |
| CALB1 | metanephric connecting tubule development; metanephric distal convoluted tubule development; metanephric collecting duct development; retina development in camera-type eye; regulation of synaptic plasticity; metanephric ureteric bud development; retina layer formation; locomotory behavior; learning or memory | |
| CALCA | endothelial cell migration; positive regulation of interleukin-8 production; positive regulation of macrophage differentiation; negative regulation of osteoclast differentiation; positive regulation of interleukin-1 alpha production; activation of protein kinase activity; negative regulation of neurological system process; receptor internalization; positive regulation of cAMP biosynthetic process; negative regulation of ossification; positive regulation of adenylate cyclase activity; negative regulation of blood pressure; positive regulation of ossification; negative regulation of bone resorption; positive regulation of cell adhesion; negative regulation of transcription, DNA-dependent; positive regulation of vasodilation; negative regulation of smooth muscle contraction; response to pain; regulation of inflammatory response; detection of temperature stimulus involved in sensory perception of pain; cytosolic calcium ion homeostasis; elevation of cytosolic calcium ion concentration involved in G-protein signal | |
| CALCOCO1 | transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; intracellular steroid hormone receptor signaling pathway; Wnt receptor signaling pathway; signal transduction | |
| CALCOCO2 | response to interferon-gamma; viral reproduction | |
| CALCR | protein localization in plasma membrane; response to glucocorticoid stimulus; positive regulation of adenylate cyclase activity; receptor internalization; positive regulation of cAMP biosynthetic process; protein transport; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity; activation of adenylate cyclase activity; activation of adenylate cyclase activity by G-protein signaling pathway | |
| CALCRL | cAMP biosynthetic process; cellular response to sucrose stimulus; negative regulation of inflammatory response; positive regulation of smooth muscle cell proliferation; positive regulation of cAMP biosynthetic process; angiogenesis; calcium ion transport; regulation of muscle contraction; G-protein signaling, coupled to cyclic nucleotide second messenger; activation of adenylate cyclase activity by G-protein signaling pathway; heart development; protein transport; receptor internalization | |
| CALD1 | cellular component movement; muscle contraction; positive regulation of protein binding; actin filament bundle assembly | |
| CALHM1 | ion transport | |
| CALHM2 | - | |
| CALML3 | - | |
| CALML5 | signal transduction; epidermis development | |
| CALML6 | - | |
| CALN1 | - | |
| CALR | antigen processing and presentation of exogenous peptide antigen via MHC class I; glucocorticoid receptor signaling pathway; cellular protein metabolic process; regulation of apoptotic process; post-translational protein modification; negative regulation of intracellular steroid hormone receptor signaling pathway; response to drug; regulation of meiosis; cellular senescence; protein localization to nucleus; response to testosterone stimulus; cardiac muscle cell differentiation; negative regulation of neuron differentiation; positive regulation of DNA replication; positive regulation of cell cycle; negative regulation of transcription, DNA-dependent; negative regulation of retinoic acid receptor signaling pathway; positive regulation of phagocytosis; protein stabilization; sequestering of calcium ion; protein maturation by protein folding; cellular response to organic substance; cellular response to lithium ion; endoplasmic reticulum unfolded protein response; response to estradiol stimulus; negative regulatio | |
| CALR3 | cell differentiation; spermatogenesis; protein folding | |
| CALU | platelet degranulation; blood coagulation; platelet activation | |
| CAMK1D | positive regulation of respiratory burst; inflammatory response; nervous system development; positive regulation of neuron projection development; positive regulation of CREB transcription factor activity; regulation of apoptotic process; positive regulation of phagocytosis; regulation of dendrite development; regulation of granulocyte chemotaxis; positive regulation of neutrophil chemotaxis | |
| CAMK1G | - | |
| CAMK2A | positive regulation of NF-kappaB transcription factor activity; cytokine-mediated signaling pathway; synaptic transmission; protein phosphorylation; interferon-gamma-mediated signaling pathway | |
| CAMK2B | response to cadmium ion; protein autophosphorylation; regulation of long-term neuronal synaptic plasticity; cell differentiation; regulation of synaptic transmission, cholinergic; induction of apoptosis in response to chemical stimulus; positive regulation of neuron projection development; neuromuscular process controlling balance; regulation of synapse structural plasticity; regulation of calcium ion transport; interferon-gamma-mediated signaling pathway; activation of meiosis involved in egg activation; regulation of dendritic spine development; positive regulation of dendritic spine morphogenesis; positive regulation of synapse maturation; peptidyl-serine phosphorylation; cytokine-mediated signaling pathway; G1/S transition of mitotic cell cycle; inhibitory G-protein coupled receptor phosphorylation; protein phosphorylation; signal transduction; synaptic transmission; multicellular organismal development; nervous system development; regulation of skeletal muscle adaptation | |
| CAMK2D | regulation of cellular localization; interferon-gamma-mediated signaling pathway; regulation of ryanodine-sensitive calcium-release channel activity; cardiac muscle contraction; protein autophosphorylation; cytokine-mediated signaling pathway; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; calcium ion transport; positive regulation of cardiac muscle hypertrophy; regulation of heart contraction; synaptic transmission; protein phosphorylation; regulation of cell growth; G1/S transition of mitotic cell cycle | |
| CAMK2G | interferon-gamma-mediated signaling pathway; regulation of calcium ion transport; cell differentiation; insulin secretion; protein phosphorylation; synaptic transmission; multicellular organismal development; nervous system development; regulation of skeletal muscle adaptation; cytokine-mediated signaling pathway | |
| CAMK2N1 | negative regulation of phosphorylation; negative regulation of catalytic activity | |
| CAMK4 | myeloid dendritic cell cytokine production; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of osteoclast differentiation; myeloid dendritic cell differentiation; regulation of T cell differentiation in thymus; fibroblast growth factor receptor signaling pathway; long-term memory; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; inflammatory response; protein phosphorylation; synaptic transmission | |
| CAMKK1 | synaptic transmission | |
| CAMKK2 | MAPK cascade; calcium-mediated signaling; regulation of protein kinase activity; positive regulation of transcription, DNA-dependent; protein autophosphorylation; protein phosphorylation | |
| CAMKV | - | |
| CAMLG | receptor recycling; defense response; signal transduction; epidermal growth factor receptor signaling pathway | |
| CAMSAP3 | negative regulation of phosphatase activity; epithelial cell-cell adhesion; regulation of microtubule cytoskeleton organization; zonula adherens maintenance; microtubule anchoring | |
| CAMTA1 | regulation of transcription, DNA-dependent | |
| CAMTA2 | cardiac muscle hypertrophy in response to stress; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter | |
| CAND1 | negative regulation of catalytic activity; regulation of transcription, DNA-dependent; protein ubiquitination; cell differentiation | |
| CAND2 | positive regulation of transcription, DNA-dependent | |
| CAPG | barbed-end actin filament capping; protein complex assembly; cell projection assembly | |
| CAPN12 | proteolysis | |
| CAPN15 | - | |
| CAPN3 | regulation of I-kappaB kinase/NF-kappaB cascade; myofibril assembly; negative regulation of protein sumoylation; response to calcium ion; response to drug; negative regulation of apoptotic process; cellular response to calcium ion; sarcomere organization; positive regulation of proteolysis; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; muscle cell homeostasis; regulation of catalytic activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of release of sequestered calcium ion into cytosol; muscle structure development; response to muscle activity; autolysis; protein complex assembly; proteolysis; apoptotic process; signal transduction; muscle organ development; positive regulation of satellite cell activation involved in skeletal muscle regeneration; protein localization in membrane; cellular response to salt stress | |
| CAPN6 | microtubule bundle formation; proteolysis; regulation of cytoskeleton organization | |
| CAPN7 | proteolysis | |
| CAPRIN1 | positive regulation of dendrite morphogenesis; positive regulation of dendritic spine morphogenesis; cell differentiation; negative regulation of translation | |
| CAPRIN2 | negative regulation of translation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of dendritic spine morphogenesis; positive regulation of dendrite morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of growth; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein binding; negative regulation of cell growth; cell differentiation | |
| CAPS2 | - | |
| CAPZA2 | protein complex assembly; cellular component movement; blood coagulation; actin cytoskeleton organization; innate immune response; actin filament capping | |
| CAPZA3 | actin filament capping; spermatid development; actin cytoskeleton organization | |
| CAPZB | blood coagulation; cellular component movement; cytoskeleton organization; regulation of cell morphogenesis; cell projection organization; lamellipodium assembly; actin cytoskeleton organization; actin filament capping | |
| CARD11 | positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cytokine production; signal transduction; positive regulation of B cell proliferation; T cell costimulation; positive regulation of T cell proliferation; regulation of apoptotic process; thymic T cell selection; positive regulation of interleukin-2 biosynthetic process; regulation of B cell differentiation; regulation of T cell differentiation; regulation of immune response; T cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity | |
| CARD14 | activation of NF-kappaB-inducing kinase activity; positive regulation of protein phosphorylation; regulation of apoptotic process | |
| CARD16 | regulation of apoptotic process | |
| CARD6 | regulation of apoptotic process | |
| CARD8 | positive regulation of interleukin-1 beta secretion; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of apoptotic process | |
| CARF | - | |
| CARKD | - | |
| CARM1 | regulation of intracellular estrogen receptor signaling pathway; regulation of growth plate cartilage chondrocyte proliferation; histone H3-R2 methylation; pathogenesis; positive regulation of cell proliferation; histone H3-R17 methylation; regulation of transcription, DNA-dependent; endochondral bone morphogenesis; response to cAMP; positive regulation of fat cell differentiation; interspecies interaction between organisms; small molecule metabolic process; cellular lipid metabolic process; peptidyl-arginine N-methylation; histone methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; intracellular steroid hormone receptor signaling pathway; negative regulation of protein binding; chromatin modification | |
| CARNMT1 | - | |
| CARS | tRNA aminoacylation for protein translation; cysteinyl-tRNA aminoacylation; gene expression | |
| CASC1 | - | |
| CASC5 | nucleosome assembly; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; acrosome assembly; chromosome segregation; attachment of spindle microtubules to kinetochore; negative regulation of phosphatase activity; CenH3-containing nucleosome assembly at centromere; cell division; spindle assembly checkpoint | |
| CASK | negative regulation of cell-matrix adhesion; cell adhesion; negative regulation of keratinocyte proliferation; negative regulation of wound healing; negative regulation of cellular response to growth factor stimulus | |
| CASKIN1 | signal transduction | |
| CASKIN2 | - | |
| CASP1 | activation of cysteine-type endopeptidase activity involved in apoptotic process; proteolysis; cellular response to organic substance; cellular response to mechanical stimulus; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; signal transduction; apoptotic process | |
| CASP10 | innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; induction of apoptosis by extracellular signals; induction of apoptosis; apoptotic process; proteolysis | |
| CASP2 | luteolysis; execution phase of apoptosis; apoptotic signaling pathway; cellular response to mechanical stimulus; nerve growth factor receptor signaling pathway; positive regulation of neuron apoptosis; positive regulation of apoptotic process; protein processing; induction of apoptosis by extracellular signals; metabolic process; aging; brain development; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; proteolysis; neural retina development | |
| CASP3 | induction of apoptosis by extracellular signals; B cell homeostasis; release of cytochrome c from mitochondria; DNA fragmentation involved in apoptotic nuclear change; proteolysis; apoptotic process; induction of apoptosis; cellular component disassembly involved in apoptosis; response to DNA damage stimulus; sensory perception of sound; nerve growth factor receptor signaling pathway; negative regulation of activated T cell proliferation; negative regulation of cyclin-dependent protein kinase activity; cell fate commitment; positive regulation of neuron apoptosis; negative regulation of apoptotic process; T cell homeostasis; regulation of apoptotic process; heart development; negative regulation of phosphorylation; response to tumor necrosis factor; negative regulation of B cell proliferation; nuclear fragmentation involved in apoptotic nuclear change; keratinocyte differentiation; protein processing; response to wounding; response to UV; activation of cysteine-type endopeptidase activity involved in apoptoti | |
| CASP5 | proteolysis; apoptotic process; regulation of apoptotic process; cellular response to mechanical stimulus | |
| CASP7 | positive regulation of neuron apoptosis; release of cytochrome c from mitochondria; protein processing; response to UV; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; induction of apoptosis by intracellular signals; aging; heart development; cellular component disassembly involved in apoptosis; induction of apoptosis; apoptotic process; proteolysis | |
| CASP8 | macrophage differentiation; response to estradiol stimulus; response to cold; activation of pro-apoptotic gene products; induction of apoptosis by intracellular signals; induction of apoptosis by extracellular signals; metabolic process; heart development; response to cobalt ion; cellular component disassembly involved in apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; proteolysis; neural tube formation; angiogenesis; response to lipopolysaccharide; response to tumor necrosis factor; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; response to ethanol; response to antibiotic; protein heterooligomerization; proteolysis involved in cellular protein catabolic process; nucleotide-binding oligomerization domain containing signaling pathway; cellular response to mechanical stimulus; extrinsic apoptotic | |
| CASP9 | phosphatidylinositol-mediated signaling; proteolysis; apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; response to DNA damage stimulus; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; induction of apoptosis by intracellular signals; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; response to UV; regulation of apoptotic process; positive regulation of neuron apoptosis; cellular response to dexamethasone stimulus; nerve growth factor receptor signaling pathway | |
| CASQ2 | striated muscle contraction; heart development | |
| CASR | calcium ion import; ossification; detection of calcium ion; cellular calcium ion homeostasis; G-protein coupled receptor signaling pathway; chemosensory behavior; anatomical structure morphogenesis; calcium-mediated signaling | |
| CASS4 | cell adhesion | |
| CAST | negative regulation of endopeptidase activity | |
| CASZ1 | regulation of transcription, DNA-dependent | |
| CATIP | - | |
| CATSPER1 | ciliary or flagellar motility; cell differentiation; sperm motility; ion transport; fusion of sperm to egg plasma membrane; spermatogenesis; transmembrane transport; multicellular organismal development | |
| CATSPER3 | ion transport; multicellular organismal development; spermatogenesis; cell differentiation; transmembrane transport | |
| CATSPER4 | transmembrane transport; cell differentiation; spermatogenesis; multicellular organismal development; ion transport | |
| CATSPERB | spermatogenesis; cell differentiation; multicellular organismal development | |
| CATSPERD | - | |
| CATSPERG | cell differentiation; spermatogenesis; multicellular organismal development | |
| CAV2 | mitochondrion organization; caveola assembly; positive regulation of dopamine receptor signaling pathway; protein oligomerization; skeletal muscle fiber development; vesicle docking; vesicle fusion; negative regulation of endothelial cell proliferation; vesicle organization; negative regulation of cell proliferation; synaptic transmission; regulation of mitosis; endoplasmic reticulum organization | |
| CAV3 | endocytosis; negative regulation of protein kinase activity; triglyceride metabolic process; regulation of ventricular cardiomyocyte membrane repolarization; negative regulation of sarcomere organization; regulation of cardiac muscle contraction; regulation of calcium ion transport via voltage-gated calcium channel activity; negative regulation of nitric-oxide synthase activity; regulation of skeletal muscle contraction; muscle cell homeostasis; elevation of cytosolic calcium ion concentration; muscle organ development; regulation of heart contraction; protein localization; negative regulation of cardiac muscle hypertrophy; cell growth; cell differentiation; positive regulation of microtubule polymerization; membrane raft organization; T-tubule organization; regulation of membrane potential; glucose homeostasis; cholesterol homeostasis; negative regulation of MAP kinase activity; negative regulation of MAPK cascade; negative regulation of cell size | |
| CBARP | - | |
| CBFA2T2 | negative regulation of neuron projection development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; epithelial cell differentiation; positive regulation of neuron projection development | |
| CBFA2T3 | cell proliferation; cell differentiation; granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter | |
| CBL | regulation of transcription, DNA-dependent; cell surface receptor signaling pathway; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; positive regulation of phosphatidylinositol 3-kinase cascade; protein ubiquitination; regulation of signaling; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of apoptotic process; positive regulation of receptor-mediated endocytosis | |
| CBLB | positive regulation of protein catabolic process; negative regulation of T cell receptor signaling pathway; T cell activation; intracellular signal transduction; regulation of signaling; response to hormone stimulus; response to gravity; cell surface receptor signaling pathway; signal transduction; immune response; NLS-bearing substrate import into nucleus; positive regulation of T cell anergy; negative regulation of alpha-beta T cell proliferation | |
| CBLC | regulation of signaling; negative regulation of epidermal growth factor-activated receptor activity; cell surface receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of MAP kinase activity; protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| CBLL1 | cell-cell adhesion; negative regulation of cell adhesion; protein ubiquitination; positive regulation of cell migration; positive regulation of endocytosis | |
| CBLN1 | synaptic transmission; nervous system development | |
| CBLN2 | - | |
| CBR3 | phylloquinone catabolic process | |
| CBR4 | fatty acid biosynthetic process; protein homotetramerization; antibiotic metabolic process | |
| CBS | regulation of cGMP metabolic process; cartilage development involved in endochondral bone morphogenesis; response to nutrient levels; cellular nitrogen compound metabolic process; homocysteine catabolic process; regulation of JUN kinase activity; small molecule metabolic process; homocysteine metabolic process; regulation of blood vessel size; response to folic acid; maternal process involved in female pregnancy; hydrogen sulfide biosynthetic process; L-cysteine catabolic process; cerebellum morphogenesis; sulfur amino acid metabolic process; endochondral ossification; blood vessel remodeling; cysteine biosynthetic process from serine; L-serine metabolic process; L-serine catabolic process; superoxide metabolic process; cellular amino acid biosynthetic process; cysteine biosynthetic process via cystathionine; transsulfuration | |
| CBX2 | cell differentiation; chromatin modification; negative regulation of transcription from RNA polymerase II promoter; development of primary sexual characteristics; negative regulation of transcription, DNA-dependent | |
| CBX5 | blood coagulation; negative regulation of transcription, DNA-dependent; interspecies interaction between organisms | |
| CBX6 | regulation of transcription, DNA-dependent; chromatin modification; negative regulation of transcription from RNA polymerase II promoter | |
| CBX8 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; chromatin modification; histone ubiquitination | |
| CC2D1A | regulation of transcription, DNA-dependent; signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| CC2D2B | - | |
| CCAR1 | gene expression; RNA splicing; cell cycle; apoptotic process; regulation of transcription, DNA-dependent; nuclear mRNA splicing, via spliceosome | |
| CCAR2 | positive regulation of apoptotic process; apoptotic process; negative regulation of catalytic activity | |
| CCBE1 | lymphangiogenesis; multicellular organismal development; venous blood vessel morphogenesis; sprouting angiogenesis | |
| CCBL2 | cellular amino acid metabolic process; kynurenine metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; biosynthetic process; tryptophan catabolic process | |
| CCDC102A | - | |
| CCDC102B | - | |
| CCDC110 | - | |
| CCDC114 | - | |
| CCDC115 | - | |
| CCDC116 | - | |
| CCDC117 | - | |
| CCDC120 | - | |
| CCDC125 | - | |
| CCDC13 | - | |
| CCDC130 | response to virus | |
| CCDC138 | - | |
| CCDC141 | - | |
| CCDC148 | - | |
| CCDC151 | - | |
| CCDC153 | - | |
| CCDC157 | - | |
| CCDC158 | - | |
| CCDC170 | - | |
| CCDC171 | - | |
| CCDC172 | - | |
| CCDC178 | - | |
| CCDC18 | - | |
| CCDC181 | - | |
| CCDC185 | - | |
| CCDC186 | - | |
| CCDC189 | - | |
| CCDC191 | - | |
| CCDC22 | - | |
| CCDC27 | - | |
| CCDC28B | - | |
| CCDC34 | - | |
| CCDC36 | - | |
| CCDC38 | - | |
| CCDC40 | axonemal dynein complex assembly; epithelial cilium movement involved in determination of left/right asymmetry; flagellar cell motility; ciliary cell motility | |
| CCDC47 | post-embryonic development; calcium ion homeostasis; embryo development; ER overload response | |
| CCDC50 | - | |
| CCDC62 | - | |
| CCDC65 | - | |
| CCDC68 | - | |
| CCDC69 | - | |
| CCDC7 | - | |
| CCDC70 | - | |
| CCDC73 | - | |
| CCDC77 | - | |
| CCDC80 | positive regulation of cell-substrate adhesion; extracellular matrix organization | |
| CCDC81 | - | |
| CCDC83 | - | |
| CCDC86 | interspecies interaction between organisms | |
| CCDC87 | - | |
| CCDC88A | regulation of neuron projection development; microtubule cytoskeleton organization; regulation of protein phosphorylation; regulation of cell proliferation; regulation of DNA replication; nervous system development; cellular membrane organization; cell migration; lamellipodium assembly; activation of protein kinase B activity; regulation of actin cytoskeleton organization; TOR signaling cascade | |
| CCDC88B | microtubule cytoskeleton organization | |
| CCDC9 | - | |
| CCDC91 | protein transport | |
| CCDC93 | - | |
| CCDC96 | - | |
| CCDC97 | - | |
| CCER1 | - | |
| CCIN | cell differentiation; spermatogenesis; multicellular organismal development | |
| CCKAR | positive regulation of somatostatin secretion; positive regulation of calcium ion transport via voltage-gated calcium channel activity; response to glucocorticoid stimulus; response to steroid hormone stimulus; regulation of hormone secretion; regulation of potassium ion transport; response to nutrient; cellular response to hormone stimulus; response to starvation; axonogenesis; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; reduction of food intake in response to dietary excess; neuron migration; gastric acid secretion; temperature homeostasis; digestion; feeding behavior; response to heat; insulin secretion; pancreatic juice secretion; forebrain development; pancreas development; organ regeneration; actin cytoskeleton reorganization; response to lipopolysaccharide; response to radiation | |
| CCKBR | cell proliferation; positive regulation of cell proliferation; positive regulation of synaptic transmission, GABAergic; response to insulin stimulus; regulation of sensory perception of pain; positive regulation of synaptic transmission, glutamatergic; estrous cycle phase; ERK1 and ERK2 cascade; positive regulation of somatostatin secretion; sensory perception; digestion; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; cell surface receptor signaling pathway; apoptotic process; behavioral defense response; histamine secretion; feeding behavior | |
| CCL17 | chemotaxis; inflammatory response; immune response; G-protein coupled receptor signaling pathway; cell-cell signaling; multicellular organismal development | |
| CCL23 | cell-cell signaling; G-protein coupled receptor signaling pathway; inflammatory response; negative regulation of cell proliferation; negative regulation of C-C chemokine binding; immune response; signal transduction; monocyte chemotaxis; cellular calcium ion homeostasis; chemotaxis | |
| CCL24 | cytoskeleton organization; positive regulation of cell migration; positive regulation of inflammatory response; positive regulation of angiogenesis; positive regulation of Rac GTPase activity; positive regulation of actin filament polymerization; signal transduction; positive regulation of endothelial cell proliferation; immune response; chemotaxis; inflammatory response; eosinophil chemotaxis; cell-cell signaling; regulation of cell shape | |
| CCM2 | multicellular organismal development; integrin-mediated signaling pathway; vasculogenesis; stress-activated MAPK cascade; endothelial tube morphogenesis | |
| CCM2L | - | |
| CCNA1 | male meiosis I; spermatogenesis; cell division; regulation of cyclin-dependent protein kinase activity; G1/S transition of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; mitotic cell cycle; mitosis | |
| CCNB1IP1 | organ growth; blastocyst formation; apoptotic process; meiotic metaphase I; spermatid development; chiasma assembly | |
| CCNB2 | growth; T cell homeostasis; thymus development; regulation of G2/M transition of mitotic cell cycle; cell division; mitosis; in utero embryonic development; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; cell cycle checkpoint | |
| CCNB3 | cell division; cell cycle; meiosis; regulation of cyclin-dependent protein kinase activity; regulation of G2/M transition of mitotic cell cycle | |
| CCND1 | mitotic cell cycle G1/S transition DNA damage checkpoint; positive regulation of cyclin-dependent protein kinase activity; response to vitamin E; Leydig cell differentiation; positive regulation of mammary gland epithelial cell proliferation; regulation of phosphorylation; response to drug; response to estrogen stimulus; fat cell differentiation; response to ethanol; regulation of catalytic activity; cell division; response to corticosterone stimulus; response to calcium ion; canonical Wnt receptor signaling pathway; mammary gland alveolus development; response to UV-A; cellular response to organic substance; organ regeneration; re-entry into mitotic cell cycle; liver development; positive regulation of protein phosphorylation; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; G1 phase of mitotic cell cycle; response to DNA damage stimulus; lactation; positive regulation of cell proliferation; endoplasmic reticulum unfolded protein response; negative regulation of epith | |
| CCND2 | response to estradiol stimulus; response to cAMP; cell division; positive regulation of epithelial cell proliferation; positive regulation of cyclin-dependent protein kinase activity; regulation of neuron differentiation; ovarian follicle development; liver development; positive regulation of protein phosphorylation; spermatogenesis; response to ethanol; response to peptide hormone stimulus; response to testosterone stimulus; cellular response to insulin stimulus; response to organic cyclic compound | |
| CCNE2 | mitotic cell cycle; cell cycle checkpoint; regulation of cyclin-dependent protein kinase activity; G1/S transition of mitotic cell cycle; cell division | |
| CCNF | re-entry into mitotic cell cycle; placenta development; cell cycle; mitosis; negative regulation of centrosome duplication; protein ubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division | |
| CCNJ | - | |
| CCNL1 | regulation of transcription, DNA-dependent; RNA processing; regulation of cyclin-dependent protein kinase activity | |
| CCNL2 | regulation of cyclin-dependent protein kinase activity; regulation of transcription, DNA-dependent; RNA processing | |
| CCNT1 | cell division; regulation of cyclin-dependent protein kinase activity; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; protein phosphorylation; cell cycle; gene expression; viral reproduction; interspecies interaction between organisms; positive regulation of viral transcription | |
| CCNT2 | cell division; transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of cyclin-dependent protein kinase activity; cell cycle; gene expression; viral reproduction; interspecies interaction between organisms | |
| CCP110 | G2/M transition of mitotic cell cycle; mitotic cell cycle; centriole replication; centrosome duplication; regulation of cytokinesis | |
| CCPG1 | cell cycle | |
| CCR2 | cellular defense response; immune response; inflammatory response; chemotaxis; cellular calcium ion homeostasis; negative regulation of type 2 immune response; positive regulation of T-helper 1 type immune response; dendritic cell chemotaxis; blood vessel remodeling; regulation of vascular endothelial growth factor production; T-helper 17 cell chemotaxis; positive regulation of T cell extravasation; positive regulation of immune complex clearance by monocytes and macrophages; positive regulation of monocyte chemotaxis; chemokine-mediated signaling pathway; positive regulation of T cell activation; positive regulation of inflammatory response; positive regulation of alpha-beta T cell proliferation; innate immune response; interspecies interaction between organisms; astrocyte cell migration; negative regulation of eosinophil degranulation; positive regulation of tumor necrosis factor biosynthetic process; negative regulation of adenylate cyclase activity; monocyte extravasation; positive regulation of interleuk | |
| CCR3 | eosinophil chemotaxis; cellular defense response; inflammatory response; cell adhesion; chemotaxis; mast cell chemotaxis; positive regulation of endothelial cell proliferation; G-protein signaling, coupled to cAMP nucleotide second messenger; elevation of cytosolic calcium ion concentration; interspecies interaction between organisms; positive regulation of angiogenesis; ERK1 and ERK2 cascade | |
| CCR4 | inflammatory response; chemotaxis; elevation of cytosolic calcium ion concentration; immune response; tolerance induction; neuron migration | |
| CCR5 | signaling; calcium ion transport; calcium-mediated signaling; entry into host cell; interspecies interaction between organisms; response to cholesterol; cellular response to lipopolysaccharide; elevation of cytosolic calcium ion concentration; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; initiation of viral infection; chemotaxis; inflammatory response; immune response; cellular defense response; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; viral reproduction; cell-cell signaling; MAPK cascade; dendritic cell chemotaxis | |
| CCR6 | elevation of cytosolic calcium ion concentration; dendritic cell chemotaxis; cellular component movement; chemotaxis; immune response; humoral immune response; cellular defense response; signal transduction; innate immune response | |
| CCR7 | positive regulation of interleukin-12 production; positive regulation of JNK cascade; cell maturation; positive regulation of cell adhesion; positive regulation of protein kinase activity; dendritic cell chemotaxis; positive regulation of glycoprotein biosynthetic process; positive regulation of actin filament polymerization; positive regulation of pseudopodium assembly; G-protein coupled receptor signaling pathway; immune response; inflammatory response; chemotaxis; positive regulation of humoral immune response; positive regulation of hypersensitivity; positive regulation of dendritic cell antigen processing and presentation; myeloid dendritic cell chemotaxis; regulation of interleukin-1 beta secretion; T cell costimulation; ruffle organization; positive regulation of cell-matrix adhesion; response to lipopolysaccharide; immunological synapse formation; negative thymic T cell selection; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; r | |
| CCR9 | elevation of cytosolic calcium ion concentration; cellular defense response; G-protein coupled receptor signaling pathway; chemotaxis; immune response | |
| CCRL2 | - | |
| CCS | intracellular copper ion transport; superoxide metabolic process; removal of superoxide radicals; metal ion transport; copper ion transmembrane transport; oxidation-reduction process | |
| CCSER2 | - | |
| CCT2 | protein folding; chaperone-mediated protein complex assembly; 'de novo' posttranslational protein folding; cellular protein metabolic process | |
| CCT3 | 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding | |
| CCT4 | 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding | |
| CCT5 | 'de novo' posttranslational protein folding; cellular protein metabolic process; response to virus; protein folding | |
| CCT6B | spermatogenesis; protein transport; protein folding; chaperone-mediated protein complex assembly | |
| CCT8 | cellular protein metabolic process; 'de novo' posttranslational protein folding; protein folding | |
| CD101 | cell surface receptor signaling pathway | |
| CD109 | - | |
| CD14 | Toll signaling pathway; phagocytosis; apoptotic process; inflammatory response; cell surface receptor signaling pathway; response to heat; positive regulation of tumor necrosis factor production; innate immune response; positive regulation of cytokine secretion; cellular response to lipopolysaccharide; cellular response to lipoteichoic acid | |
| CD151 | cell junction assembly; hemidesmosome assembly; cell adhesion | |
| CD163 | acute-phase response; inflammatory response | |
| CD163L1 | - | |
| CD164 | immune response; cell adhesion; heterophilic cell-cell adhesion; negative regulation of cell adhesion; signal transduction; multicellular organismal development; muscle organ development; negative regulation of cell proliferation; hemopoiesis | |
| CD164L2 | - | |
| CD180 | inflammatory response; innate immune response | |
| CD1A | antigen processing and presentation; immune response | |
| CD1B | immune response; antigen processing and presentation | |
| CD1C | antigen processing and presentation; immune response; T cell activation involved in immune response | |
| CD1D | detection of bacterium; heterotypic cell-cell adhesion; antigen processing and presentation; T cell selection; interspecies interaction between organisms; positive regulation of innate immune response; antigen processing and presentation, endogenous lipid antigen via MHC class Ib; positive regulation of T cell proliferation | |
| CD1E | antigen processing and presentation; immune response | |
| CD200R1 | regulation of immune response; interspecies interaction between organisms | |
| CD22 | cell adhesion | |
| CD226 | regulation of immune response; positive regulation of Fc receptor mediated stimulatory signaling pathway; positive regulation of natural killer cell mediated cytotoxicity; cell recognition; signal transduction; cell adhesion; positive regulation of immunoglobulin mediated immune response; positive regulation of mast cell activation; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; cytokine production | |
| CD244 | signal transduction; blood coagulation; leukocyte migration | |
| CD247 | viral reproduction; cell surface receptor signaling pathway; T cell costimulation; interspecies interaction between organisms; regulation of defense response to virus by virus; regulation of immune response; T cell receptor signaling pathway | |
| CD248 | - | |
| CD28 | cytokine biosynthetic process; positive regulation of T cell proliferation; T cell activation; regulatory T cell differentiation; positive regulation of viral genome replication; positive regulation of interleukin-2 biosynthetic process; positive regulation of anti-apoptosis; positive regulation of mitosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of isotype switching to IgG isotypes; regulation of defense response to virus by virus; positive regulation of alpha-beta T cell proliferation; negative thymic T cell selection; positive regulation of translation; positive regulation of inflammatory response to antigenic stimulus; immune response; T cell costimulation; humoral immune response; cell surface receptor signaling pathway; induction of apoptosis by extracellular signals; viral reproduction | |
| CD2AP | substrate-dependent cell migration, cell extension; protein complex assembly; cell cycle; mitosis; signal transduction; cell division | |
| CD2BP2 | assembly of spliceosomal tri-snRNP; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; negative regulation of phosphatase activity | |
| CD300C | cellular defense response | |
| CD300LG | - | |
| CD36 | cholesterol transport; positive regulation of blood coagulation; platelet activation; cGMP-mediated signaling; lipid storage; plasma membrane long-chain fatty acid transport; positive regulation of cholesterol storage; positive regulation of macrophage derived foam cell differentiation; negative regulation of gene expression; defense response to Gram-positive bacterium; blood coagulation; positive regulation of interleukin-6 production; positive regulation of interleukin-12 production; positive regulation of tumor necrosis factor production; plasma lipoprotein particle clearance; low-density lipoprotein particle clearance; response to stilbenoid; antigen processing and presentation of exogenous peptide antigen via MHC class I; lipoprotein transport; negative regulation of transcription factor import into nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptotic cell clearance; positive regulation of MAPK cascade; negative regulation of growth of symbiont in host; cellular lipid metabolic pr | |
| CD3E | positive regulation of interferon-gamma production; T cell costimulation; induction of apoptosis by extracellular signals; positive regulation of alpha-beta T cell proliferation; response to nutrient; positive regulation of interleukin-4 production; T cell differentiation in thymus; positive regulation of T cell proliferation; T cell activation; regulation of apoptotic process; negative thymic T cell selection; positive regulation of interleukin-2 biosynthetic process; G-protein coupled receptor signaling pathway; signal complex assembly; transmembrane receptor protein tyrosine kinase signaling pathway; cell surface receptor signaling pathway; protein complex assembly; positive regulation of T cell anergy; T cell receptor signaling pathway; positive regulation of calcium-mediated signaling; regulation of immune response; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of smoothened signaling pathway | |
| CD3EAP | transmembrane receptor protein tyrosine kinase signaling pathway; rRNA transcription | |
| CD40 | positive regulation of MAP kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of Cdc42 GTPase activity; positive regulation of tyrosine phosphorylation of Stat1 protein; B cell proliferation; positive regulation of Rac GTPase activity; positive regulation of interleukin-12 production; positive regulation of B cell proliferation; platelet activation; signal transduction; inflammatory response; cellular calcium ion homeostasis; protein complex assembly; immune response-regulating cell surface receptor signaling pathway; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of isotype switching to IgG isotypes; regulation of immune response; regulation of immunoglobulin secretion; positive regulation of NF-kappaB transcription factor activity; defense response to virus; cellular response to mechanical stimulus; positive regulation of protein kinase C signaling cascade; positive regulati | |
| CD40LG | platelet activation; positive regulation of MHC class II biosynthetic process; B cell differentiation; positive regulation of B cell proliferation; positive regulation of interferon-gamma production; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; B cell proliferation; isotype switching; immune response; inflammatory response; anti-apoptosis; positive regulation of immune response to tumor cell; positive regulation of endothelial cell apoptosis; leukocyte cell-cell adhesion; regulation of immunoglobulin secretion; regulation of immune response | |
| CD47 | integrin-mediated signaling pathway; leukocyte migration; positive regulation of T cell activation; positive regulation of cell-cell adhesion; positive regulation of cell proliferation; blood coagulation; cell adhesion | |
| CD48 | defense response; signal transduction; blood coagulation; T cell activation; mast cell activation; leukocyte migration | |
| CD5 | cell proliferation; cell recognition; induction of apoptosis by extracellular signals; T cell costimulation | |
| CD55 | respiratory burst; complement activation, classical pathway; elevation of cytosolic calcium ion concentration; innate immune response | |
| CD58 | leukocyte migration; cell-cell adhesion; blood coagulation; cell adhesion | |
| CD5L | apoptotic process; cellular defense response | |
| CD6 | cell adhesion | |
| CD68 | - | |
| CD7 | homeostasis of number of cells within a tissue; T cell activation; transmembrane receptor protein tyrosine kinase signaling pathway; immune response | |
| CD79A | cell surface receptor signaling pathway; B cell differentiation; B cell proliferation; B cell activation; B cell receptor signaling pathway | |
| CD83 | defense response; positive regulation of CD4-positive, alpha-beta T cell differentiation; humoral immune response; negative regulation of interleukin-4 production; response to organic cyclic compound; positive regulation of interleukin-10 production; positive regulation of interleukin-2 production; signal transduction | |
| CD9 | paranodal junction assembly; platelet degranulation; cellular component movement; cell adhesion; brain development; blood coagulation; negative regulation of cell proliferation; response to water deprivation; oligodendrocyte development; platelet activation; fusion of sperm to egg plasma membrane | |
| CD96 | cell adhesion; regulation of immune response; immune response | |
| CD99L2 | cell adhesion | |
| CDAN1 | - | |
| CDC14A | cell proliferation; cell division; cell cycle | |
| CDC16 | cell division; cell cycle checkpoint; mitotic cell cycle; mitosis; regulation of mitosis; mitotic cell cycle spindle assembly checkpoint; cell proliferation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination | |
| CDC20B | - | |
| CDC23 | mitotic cell cycle spindle assembly checkpoint; cell cycle checkpoint; protein K11-linked ubiquitination; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell division; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of mitotic metaphase/anaphase transition; protein ubiquitination; regulation of exit from mitosis; mitotic metaphase/anaphase transition; mitotic metaphase plate congression; mitosis; cell cycle; ubiquitin-dependent protein catabolic process; mitotic cell cycle; G1 phase of mitotic cell cycle | |
| CDC25A | mitotic cell cycle; G2/M transition of mitotic cell cycle; cell cycle checkpoint; regulation of cyclin-dependent protein kinase activity; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; cell division; cellular response to UV; response to radiation; cell proliferation; mitosis; DNA replication | |
| CDC25B | mitosis; protein phosphorylation; oocyte maturation; mitotic cell cycle; G2/M transition of mitotic cell cycle; female meiosis I; positive regulation of cell proliferation; peptidyl-tyrosine dephosphorylation; positive regulation of protein kinase activity; positive regulation of mitotic cell cycle; cell division; positive regulation of cell cycle cytokinesis | |
| CDC25C | DNA replication; regulation of cell cycle; cell division; interspecies interaction between organisms; peptidyl-tyrosine dephosphorylation; cell proliferation; traversing start control point of mitotic cell cycle; regulation of mitosis; mitotic cell cycle; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; cell cycle checkpoint | |
| CDC26 | cell cycle checkpoint; mitotic cell cycle; mitosis; mitotic cell cycle spindle assembly checkpoint; regulation of mitotic metaphase/anaphase transition; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination | |
| CDC37 | regulation of type I interferon-mediated signaling pathway; regulation of cyclin-dependent protein kinase activity; regulation of interferon-gamma-mediated signaling pathway; protein targeting | |
| CDC42BPA | protein phosphorylation; intracellular signal transduction; actin cytoskeleton reorganization; actomyosin structure organization; cell migration | |
| CDC42BPB | actomyosin structure organization; actin cytoskeleton reorganization; protein phosphorylation; cytoskeleton organization; establishment or maintenance of cell polarity; intracellular signal transduction; signal transduction; cell migration | |
| CDC42BPG | intracellular signal transduction; protein phosphorylation; actin cytoskeleton reorganization | |
| CDC42EP1 | positive regulation of pseudopodium assembly; regulation of cell shape | |
| CDC42EP2 | positive regulation of Rho GTPase activity; positive regulation of protein complex assembly; actin filament organization; regulation of cell shape; positive regulation of pseudopodium assembly; positive regulation of actin filament polymerization; actin cytoskeleton organization | |
| CDC45 | DNA strand elongation involved in DNA replication; G1/S transition of mitotic cell cycle; DNA replication checkpoint; cell cycle checkpoint; regulation of transcription involved in G1/S phase of mitotic cell cycle; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; DNA-dependent DNA replication initiation | |
| CDC6 | traversing start control point of mitotic cell cycle; DNA replication; mitosis; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; DNA replication checkpoint; cell cycle checkpoint; negative regulation of DNA replication; negative regulation of cell proliferation; cell division; regulation of mitotic anaphase; positive regulation of cell cycle cytokinesis; positive regulation of chromosome segregation | |
| CDC7 | phosphorylation; positive regulation of cell proliferation; DNA replication; cell division; mitotic cell cycle; M/G1 transition of mitotic cell cycle; regulation of S phase; G1/S transition of mitotic cell cycle; cell cycle checkpoint | |
| CDC73 | histone H2B ubiquitination; cell cycle; histone monoubiquitination; protein destabilization; negative regulation of fibroblast proliferation; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of epithelial cell proliferation | |
| CDCA2 | cell division; mitosis; cell cycle | |
| CDCA3 | cell division; mitosis; cell cycle | |
| CDCA5 | cell division; G1/S transition of mitotic cell cycle; double-strand break repair; cell cycle; mitotic sister chromatid cohesion; interphase of mitotic cell cycle; mitosis; mitotic chromosome condensation; mitotic metaphase plate congression; regulation of cohesin localization to chromatin | |
| CDCA7L | regulation of transcription, DNA-dependent; positive regulation of cell proliferation | |
| CDCP2 | - | |
| CDH1 | cellular component disassembly involved in apoptosis; apoptotic process; cellular response to indole-3-methanol; cellular response to lithium ion; regulation of immune response; positive regulation of transcription, DNA-dependent; cell-cell junction organization; positive regulation of transcription factor import into nucleus; response to drug; adherens junction organization; cell junction assembly; neuron projection development; negative regulation of cell-cell adhesion; pituitary gland development; cell-cell adhesion; response to organic substance; response to toxin; synapse assembly; homophilic cell adhesion; cell adhesion | |
| CDH10 | cell-cell adhesion; homophilic cell adhesion; cell junction assembly; adherens junction organization; cell-cell junction organization | |
| CDH11 | cell-cell junction organization; skeletal system development; ossification; cell adhesion; homophilic cell adhesion; cell-cell adhesion; cell junction assembly; adherens junction organization | |
| CDH12 | cell-cell junction organization; adherens junction organization; cell junction assembly; cell-cell adhesion; homophilic cell adhesion | |
| CDH15 | cell adhesion; homophilic cell adhesion; cell junction assembly; adherens junction organization; muscle cell differentiation; cell-cell junction organization; positive regulation of muscle cell differentiation | |
| CDH16 | homophilic cell adhesion; cell adhesion | |
| CDH18 | cell-cell junction organization; adherens junction organization; cell junction assembly; homophilic cell adhesion; cell adhesion | |
| CDH19 | cell adhesion; homophilic cell adhesion; cell-cell adhesion | |
| CDH2 | striated muscle cell differentiation; positive regulation of muscle cell differentiation; negative regulation of canonical Wnt receptor signaling pathway; regulation of axonogenesis; blood vessel morphogenesis; cell-cell junction organization; positive regulation of MAPK cascade; muscle cell differentiation; regulation of Rho protein signal transduction; adherens junction organization; regulation of protein localization; regulation of myelination; cell migration; calcium-dependent cell-cell adhesion; synapse assembly; heterophilic cell-cell adhesion; cell adhesion; cell junction assembly; homophilic cell adhesion | |
| CDH20 | cell-cell adhesion; homophilic cell adhesion | |
| CDH22 | cell adhesion; homophilic cell adhesion | |
| CDH24 | homophilic cell adhesion; cell junction assembly; cell-cell adhesion; cell-cell junction organization; adherens junction organization | |
| CDH26 | homophilic cell adhesion; cell adhesion | |
| CDH3 | cell-cell junction organization; cell adhesion; homophilic cell adhesion; visual perception; cell junction assembly; adherens junction organization; response to stimulus | |
| CDH4 | cell junction assembly; homophilic cell adhesion; heterophilic cell-cell adhesion; axon guidance; adherens junction organization; cell-cell junction organization; positive regulation of axon extension; cell adhesion | |
| CDH5 | blood vessel maturation; regulation of establishment of cell polarity; cell-cell junction organization; adherens junction organization; cell junction assembly; negative regulation of cell proliferation; homophilic cell adhesion; cell adhesion | |
| CDH6 | homophilic cell adhesion; cell adhesion; cell junction assembly; adherens junction organization; cell-cell junction organization | |
| CDH7 | cell-cell junction organization; adherens junction organization; cell junction assembly; cell-cell adhesion; homophilic cell adhesion | |
| CDH8 | cell-cell junction organization; adherens junction organization; cell junction assembly; homophilic cell adhesion; cell adhesion | |
| CDH9 | adherens junction organization; cell-cell junction organization; cell-cell adhesion; cell junction assembly; homophilic cell adhesion | |
| CDHR1 | cell adhesion; homophilic cell adhesion; photoreceptor cell maintenance | |
| CDHR2 | cell adhesion; negative regulation of cell growth; homophilic cell adhesion | |
| CDHR5 | cell adhesion; calcium-dependent cell-cell adhesion; homophilic cell adhesion | |
| CDK1 | protein localization to kinetochore; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of protein import into nucleus, translocation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; organ regeneration; chromosome condensation; cell migration; response to activity; response to amine stimulus; response to organic cyclic compound; regulation of Schwann cell differentiation; positive regulation of gene expression; response to toxin; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; response to copper ion; cellular response to hydrogen peroxide; positive regulation of cardiac muscle cell proliferation; ventricular cardiac muscle cell development; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic | |
| CDK12 | mRNA processing; RNA splicing; regulation of MAP kinase activity; phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation | |
| CDK13 | protein phosphorylation; mRNA processing; alternative nuclear mRNA splicing, via spliceosome; phosphorylation of RNA polymerase II C-terminal domain; interspecies interaction between organisms; hemopoiesis; regulation of mitosis; multicellular organismal development; positive regulation of cell proliferation; RNA splicing | |
| CDK14 | G2/M transition of mitotic cell cycle; cell cycle; regulation of canonical Wnt receptor signaling pathway; cell division; Wnt receptor signaling pathway | |
| CDK2 | phosphorylation; positive regulation of cell proliferation; blood coagulation; Ras protein signal transduction; meiosis; traversing start control point of mitotic cell cycle; histone phosphorylation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mitotic cell cycle G1/S transition DNA damage checkpoint; positive regulation of transcription, DNA-dependent; centrosome duplication; cell division; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of gene silencing; mitosis; cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; potassium ion transport; protein phosphorylation; DNA repair; regulation of DNA replication; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2 phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; cellular response t | |
| CDK20 | cell division; multicellular organismal development | |
| CDK3 | G1/S transition of mitotic cell cycle; mitosis; cell proliferation; G0 to G1 transition; cell division | |
| CDK4 | cell division; regulation of cell cycle; positive regulation of fibroblast proliferation; response to drug; regulation of gene expression; positive regulation of cell proliferation; cell cycle; protein phosphorylation; mitotic cell cycle; S phase of mitotic cell cycle; signal transduction; G1/S transition of mitotic cell cycle; G1 phase of mitotic cell cycle | |
| CDK5R1 | G-protein coupled acetylcholine receptor signaling pathway; neuron projection development; neuron differentiation; cerebral cortex radially oriented cell migration; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; phosphorylation; embryo development; cell proliferation; brain development; axonal fasciculation; positive regulation of protein serine/threonine kinase activity; axon guidance; regulation of microtubule cytoskeleton organization; neuron cell-cell adhesion; protein phosphorylation; neuron migration; regulation of cyclin-dependent protein kinase activity; regulation of actin cytoskeleton organization; ionotropic glutamate receptor signaling pathway; positive regulation of neuron apoptosis; regulation of neuron differentiation; negative regulation of transcription, DNA-dependent; ephrin receptor signaling pathway; regulation of dendritic spine morphogenesis | |
| CDK5R2 | regulation of cyclin-dependent protein kinase activity | |
| CDK5RAP2 | mitotic cell cycle; regulation of spindle checkpoint; brain development; chromosome segregation; neurogenesis; negative regulation of centriole replication; microtubule cytoskeleton organization; microtubule bundle formation; regulation of neuron differentiation; centrosome organization; negative regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; establishment of mitotic spindle orientation; G2/M transition of mitotic cell cycle | |
| CDK5RAP3 | regulation of cyclin-dependent protein kinase activity; brain development; regulation of neuron differentiation | |
| CDK7 | transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; mRNA capping; protein phosphorylation; cell cycle arrest; cell proliferation; gene expression; viral reproduction; androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; cell division; termination of RNA polymerase I transcription; regulation of cyclin-dependent protein kinase activity; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; mitotic cell cycle; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; transcription from RNA polymerase II promoter; nucleotide-ex | |
| CDK8 | protein phosphorylation; gene expression; regulation of transcription, DNA-dependent | |
| CDK9 | cellular response to cytokine stimulus; negative regulation of cell cycle arrest; positive regulation of viral transcription; replication fork arrest; regulation of histone modification; viral reproduction; gene expression; cell cycle; protein phosphorylation; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of DNA repair; cell proliferation | |
| CDKAL1 | RNA modification | |
| CDKL2 | sex differentiation; signal transduction; protein phosphorylation | |
| CDKL4 | - | |
| CDKL5 | neuron migration; protein phosphorylation; positive regulation of Rac GTPase activity; positive regulation of axon extension; protein autophosphorylation; positive regulation of dendrite morphogenesis; regulation of dendrite development | |
| CDKN1A | negative regulation of cyclin-dependent protein kinase activity; negative regulation of cell growth; positive regulation of programmed cell death; negative regulation of apoptotic process; response to drug; regulation of protein import into nucleus, translocation; cellular response to extracellular stimulus; organ regeneration; positive regulation of B cell proliferation; negative regulation of phosphorylation; positive regulation of anti-apoptosis; response to arsenic-containing substance; positive regulation of fibroblast proliferation; response to corticosterone stimulus; response to hyperoxia; cellular response to ionizing radiation; cellular senescence; stress-induced premature senescence; regulation of DNA biosynthetic process; positive regulation of reactive oxygen species metabolic process; response to organic cyclic compound; cell cycle checkpoint; regulation of cyclin-dependent protein kinase activity; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; S phase of mitotic cell cyc | |
| CDKN2A | senescence-associated heterochromatin focus assembly; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cyclin-dependent protein kinase activity; positive regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of phosphorylation; protein stabilization; positive regulation of smooth muscle cell apoptosis; positive regulation of protein sumoylation; negative regulation of immature T cell proliferation in thymus; regulation of protein export from nucleus; somatic stem cell division; negative regulation of ubiquitin-protein ligase activity; protein K63-linked ubiquitination; positive regulation of cell cycle arrest; cellular senescence; replicative senescence; positive regulation of macrophage apoptosis; positive regulation of cellular senescence; activation of cysteine-type endopeptidase activity involved in apoptotic proce | |
| CDO1 | small molecule metabolic process; oxidation-reduction process; response to glucocorticoid stimulus; response to ethanol; response to amino acid stimulus; taurine biosynthetic process; cellular nitrogen compound metabolic process; response to glucagon stimulus; L-cysteine catabolic process; response to organic nitrogen; lactation; inflammatory response; cysteine metabolic process; sulfur amino acid catabolic process; sulfur amino acid biosynthetic process; sulfur amino acid metabolic process; response to cAMP | |
| CDON | muscle cell differentiation; positive regulation of muscle cell differentiation; cell adhesion | |
| CDRT4 | - | |
| CDS1 | CDP-choline pathway; phosphatidylinositol biosynthetic process; signal transduction; phototransduction; phospholipid biosynthetic process; CDP-diacylglycerol biosynthetic process | |
| CDT1 | regulation of DNA-dependent DNA replication initiation; S phase of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; DNA replication checkpoint; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; regulation of S phase of mitotic cell cycle | |
| CDX2 | regulation of transcription, DNA-dependent; labyrinthine layer development; positive regulation of cell differentiation; somatic stem cell maintenance; anterior/posterior pattern specification; organ morphogenesis; pattern specification process; transcription from RNA polymerase II promoter; placenta development; trophectodermal cell differentiation; blastocyst development; blood vessel development; negative regulation of transcription from RNA polymerase II promoter | |
| CEACAM1 | cell migration; integrin-mediated signaling pathway; homophilic cell adhesion; angiogenesis | |
| CEACAM7 | - | |
| CEACAM8 | immune response | |
| CEBPZ | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| CECR1 | purine ribonucleoside monophosphate biosynthetic process; hypoxanthine salvage; inosine biosynthetic process; multicellular organismal development; adenosine catabolic process | |
| CECR5 | metabolic process | |
| CECR6 | - | |
| CELA1 | Wnt receptor signaling pathway; post-embryonic development; inflammatory response; proteolysis; negative regulation of transcription from RNA polymerase II promoter; exocrine pancreas development; multicellular organism growth; regulation of cell proliferation; regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; pancreas morphogenesis | |
| CELF1 | embryo development; mRNA processing; regulation of RNA splicing; mRNA splice site selection; germ cell development; RNA interference | |
| CELF2 | RNA processing; mRNA processing; regulation of heart contraction | |
| CELF3 | RNA splicing; sperm motility; positive regulation of nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome; spermatogenesis; regulation of alternative nuclear mRNA splicing, via spliceosome | |
| CELF6 | mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome | |
| CELSR1 | neuropeptide signaling pathway; Rho protein signal transduction; G-protein coupled receptor signaling pathway; multicellular organismal development; central nervous system development; homophilic cell adhesion; cell adhesion; hair follicle development; anterior/posterior pattern specification; neural tube closure; neuron migration; establishment of planar polarity; locomotory behavior; inner ear morphogenesis; planar cell polarity pathway involved in neural tube closure; lateral sprouting involved in lung morphogenesis; protein localization involved in establishment of planar polarity; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; establishment of body hair planar orientation; apical protein localization; regulation of actin cytoskeleton organization; establishment of planar polarity of embryonic epithelium; wound healing | |
| CELSR2 | spermatogenesis; multicellular organismal development; neuron migration; Wnt receptor signaling pathway; neuropeptide signaling pathway; neural plate anterior/posterior regionalization; regulation of cell-cell adhesion; dendrite morphogenesis; regulation of transcription, DNA-dependent; cell adhesion; homophilic cell adhesion; G-protein coupled receptor signaling pathway | |
| CELSR3 | neuropeptide signaling pathway; multicellular organismal development; G-protein coupled receptor signaling pathway; homophilic cell adhesion; cell adhesion; neuron migration; axonal fasciculation | |
| CEMIP | - | |
| CENPB | regulation of transcription, DNA-dependent | |
| CENPE | mitotic cell cycle spindle assembly checkpoint; mitotic metaphase; M phase of mitotic cell cycle; positive regulation of attachment of spindle microtubules to kinetochore; kinetochore assembly; cell division; mitotic metaphase plate congression; mitotic chromosome movement towards spindle pole; microtubule-based movement; mitotic cell cycle; positive regulation of protein kinase activity; positive regulation of mitotic metaphase/anaphase transition; establishment of protein localization; blood coagulation; multicellular organismal development; regulation of mitosis; mitotic prometaphase; regulation of developmental process | |
| CENPF | multicellular organismal development; mitotic cell cycle spindle assembly checkpoint; protein transport; chromosome segregation; DNA replication; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle; G2 phase of mitotic cell cycle; cell proliferation; muscle organ development; kinetochore assembly; metaphase plate congression; cell division; negative regulation of transcription, DNA-dependent; response to drug; cell differentiation; regulation of striated muscle tissue development; regulation of G2/M transition of mitotic cell cycle | |
| CENPJ | cell division; centriole replication; mitotic cell cycle; regulation of centriole replication; microtubule polymerization; microtubule nucleation; G2/M transition of mitotic cell cycle | |
| CENPL | mitotic prometaphase; M phase of mitotic cell cycle; mitotic cell cycle | |
| CENPN | mitotic cell cycle; mitotic prometaphase; nucleosome assembly; CenH3-containing nucleosome assembly at centromere; M phase of mitotic cell cycle | |
| CENPO | nucleosome assembly; mitotic prometaphase; mitotic cell cycle; M phase of mitotic cell cycle; CenH3-containing nucleosome assembly at centromere; cell division; chromosome segregation | |
| CENPQ | mitotic prometaphase; CenH3-containing nucleosome assembly at centromere; nucleosome assembly; mitotic cell cycle; M phase of mitotic cell cycle | |
| CENPT | M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle | |
| CEP104 | - | |
| CEP112 | - | |
| CEP126 | - | |
| CEP128 | - | |
| CEP131 | cell differentiation; spermatogenesis; multicellular organismal development; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| CEP135 | centriole-centriole cohesion; centriole replication; G2/M transition of mitotic cell cycle; mitotic cell cycle | |
| CEP152 | centrosome duplication; G2/M transition of mitotic cell cycle; mitotic cell cycle | |
| CEP164 | cell division; mitosis; DNA repair; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| CEP250 | regulation of centriole-centriole cohesion; centriole-centriole cohesion; G2/M transition of mitotic cell cycle; protein localization; mitotic cell cycle | |
| CEP41 | cilium assembly; protein polyglutamylation; G2/M transition of mitotic cell cycle; mitotic cell cycle | |
| CEP70 | G2/M transition of mitotic cell cycle; mitotic cell cycle | |
| CEP72 | gamma-tubulin complex localization; spindle organization; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| CEP83 | - | |
| CEP85 | - | |
| CEP85L | - | |
| CEP89 | - | |
| CEP97 | - | |
| CEPT1 | lipid metabolic process; phospholipid biosynthetic process | |
| CER1 | negative regulation of Wnt receptor signaling pathway; cellular response to BMP stimulus; negative regulation of mesoderm development; negative regulation of BMP signaling pathway by extracellular sequestering of BMP; bone mineralization; negative regulation of activin receptor signaling pathway; BMP signaling pathway; growth plate cartilage chondrocyte proliferation; ureteric bud development | |
| CERCAM | cell adhesion; leukocyte cell-cell adhesion; lipopolysaccharide biosynthetic process; cellular component movement | |
| CERKL | anti-apoptosis; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway | |
| CERS4 | sphingolipid metabolic process; lipid biosynthetic process; sphingolipid biosynthetic process; small molecule metabolic process; ceramide biosynthetic process | |
| CERS5 | ceramide biosynthetic process; lipid biosynthetic process; sphingolipid biosynthetic process; sphingolipid metabolic process; small molecule metabolic process | |
| CERS6 | sphingolipid metabolic process; ceramide biosynthetic process; small molecule metabolic process; sphingolipid biosynthetic process; lipid biosynthetic process | |
| CES2 | catabolic process | |
| CES3 | - | |
| CES4A | - | |
| CES5A | - | |
| CETN2 | spermatogenesis; cell division; regulation of cytokinesis; centriole replication; mitosis; nucleotide-excision repair; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| CFAP100 | - | |
| CFAP126 | - | |
| CFAP157 | - | |
| CFAP206 | - | |
| CFAP221 | - | |
| CFAP43 | - | |
| CFAP44 | - | |
| CFAP45 | - | |
| CFAP46 | - | |
| CFAP52 | - | |
| CFAP53 | - | |
| CFAP58 | - | |
| CFAP61 | - | |
| CFAP69 | - | |
| CFAP70 | - | |
| CFAP77 | - | |
| CFH | complement activation, alternative pathway; complement activation | |
| CFHR5 | complement activation, alternative pathway | |
| CFI | proteolysis; complement activation, classical pathway; innate immune response | |
| CFP | defense response to bacterium; complement activation, alternative pathway; innate immune response; complement activation; immune response | |
| CFTR | transmembrane transport; positive regulation of vasodilation; response to estrogen stimulus; response to peptide hormone stimulus; response to drug; response to cytokine stimulus; cellular response to hormone stimulus; lung development; transepithelial chloride transport; cholesterol transport; iodide transport; bicarbonate transport; respiratory gaseous exchange; water transport; chloride transport; ion transport; transport; cholesterol biosynthetic process | |
| CGA | cellular nitrogen compound metabolic process; cellular response to hormone stimulus; luteinizing hormone secretion; signal transduction; thyroid gland development; small molecule metabolic process; negative regulation of organ growth; follicle-stimulating hormone secretion; developmental growth; gonad development; peptide hormone processing; thyroid hormone generation; cell-cell signaling | |
| CGN | - | |
| CGNL1 | - | |
| CGREF1 | cell adhesion; cell cycle arrest; negative regulation of cell proliferation; cell cycle; response to stress | |
| CH25H | cholesterol metabolic process; lipid metabolic process; fatty acid biosynthetic process; bile acid biosynthetic process; bile acid metabolic process; sterol biosynthetic process; small molecule metabolic process | |
| CHAD | regulation of cell growth | |
| CHAF1A | regulation of transcription, DNA-dependent; DNA replication; DNA repair; DNA replication-dependent nucleosome assembly; protein complex assembly; cell cycle; chromatin assembly | |
| CHAF1B | DNA replication; DNA repair; cell cycle; protein complex assembly; regulation of transcription, DNA-dependent; DNA replication-dependent nucleosome assembly; chromatin assembly | |
| CHAMP1 | attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; protein localization to kinetochore; protein localization to microtubule; sister chromatid biorientation | |
| CHCHD6 | - | |
| CHCHD7 | - | |
| CHD1 | regulation of transcription from RNA polymerase II promoter; chromatin remodeling | |
| CHD1L | chromatin remodeling; response to DNA damage stimulus; ATP catabolic process; DNA repair | |
| CHD2 | regulation of transcription from RNA polymerase II promoter | |
| CHD3 | regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; spindle organization; chromatin modification; centrosome organization | |
| CHD4 | regulation of transcription from RNA polymerase II promoter; chromatin modification | |
| CHD5 | regulation of transcription, DNA-dependent; chromatin modification | |
| CHD6 | regulation of transcription, DNA-dependent; chromatin remodeling; nervous system development | |
| CHDH | alcohol metabolic process | |
| CHEK2 | G2/M transition of mitotic cell cycle; DNA damage checkpoint; replicative senescence; cell cycle checkpoint; double-strand break repair; regulation of transcription, DNA-dependent; apoptotic process; response to DNA damage stimulus; cell cycle; spindle assembly involved in mitosis; signal transduction involved in intra-S DNA damage checkpoint; cell division; protein autophosphorylation; positive regulation of transcription, DNA-dependent; cellular protein catabolic process; signal transduction in response to DNA damage; regulation of protein catabolic process; response to gamma radiation; DNA damage response, signal transduction resulting in induction of apoptosis; DNA damage induced protein phosphorylation | |
| CHERP | RNA processing; cellular calcium ion homeostasis; nervous system development; negative regulation of cell proliferation; release of sequestered calcium ion into cytosol; positive regulation of NFAT protein import into nucleus | |
| CHGA | regulation of blood pressure | |
| CHI3L1 | positive regulation of protein kinase B signaling cascade; interleukin-8 secretion; cellular response to tumor necrosis factor; cellular response to interleukin-1; response to interleukin-6; response to interleukin-1; positive regulation of ERK1 and ERK2 cascade; cartilage development; response to tumor necrosis factor; carbohydrate metabolic process; lung development; positive regulation of peptidyl-threonine phosphorylation; response to mechanical stimulus; activation of NF-kappaB-inducing kinase activity; inflammatory response; chitin catabolic process; positive regulation of angiogenesis | |
| CHI3L2 | chitin catabolic process; carbohydrate metabolic process | |
| CHIA | chitin metabolic process; apoptotic process; cell wall chitin metabolic process; chitin catabolic process; immune response; digestion; response to fungus; carbohydrate metabolic process; production of molecular mediator involved in inflammatory response; response to acid; polysaccharide catabolic process; positive regulation of chemokine secretion | |
| CHID1 | innate immune response; chitin catabolic process; carbohydrate metabolic process | |
| CHIT1 | polysaccharide catabolic process; carbohydrate metabolic process; chitin catabolic process; immune response; response to bacterium | |
| CHKA | phosphatidylcholine biosynthetic process; choline metabolic process; phospholipid biosynthetic process; signal transduction; CDP-choline pathway; lipid metabolic process; phosphatidylethanolamine biosynthetic process; lipid transport | |
| CHKB | phosphatidylethanolamine biosynthetic process; CDP-choline pathway; muscle organ development; phospholipid biosynthetic process | |
| CHL1 | nervous system development; multicellular organismal development; signal transduction; axon guidance; cell differentiation; cell adhesion | |
| CHM | intracellular protein transport; response to stimulus; protein geranylgeranylation; visual perception; blood vessel development | |
| CHMP2A | endosome transport; cellular membrane organization; protein transport | |
| CHMP7 | cellular membrane organization; endosome transport; late endosome to vacuole transport; protein transport | |
| CHN2 | acrosome assembly; small GTPase mediated signal transduction; positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction | |
| CHODL | muscle organ development | |
| CHORDC1 | chaperone-mediated protein folding; regulation of response to stress; regulation of centrosome duplication; negative regulation of Rho-dependent protein serine/threonine kinase activity | |
| CHP2 | - | |
| CHPF | - | |
| CHPF2 | - | |
| CHPT1 | phospholipid biosynthetic process; regulation of cell growth; platelet activating factor biosynthetic process; CDP-choline pathway; phosphatidylcholine biosynthetic process; lipid metabolic process | |
| CHRDL1 | nervous system development; multicellular organismal development; BMP signaling pathway; ossification; cell differentiation | |
| CHRDL2 | cartilage development; ossification; multicellular organismal development; cell differentiation | |
| CHRM2 | synaptic transmission; response to virus; regulation of heart contraction; nervous system development; activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway; regulation of smooth muscle contraction | |
| CHRM3 | G-protein coupled receptor signaling pathway; regulation of insulin secretion; positive regulation of smooth muscle contraction; small molecule metabolic process; cell proliferation; digestion; nervous system development; G-protein coupled acetylcholine receptor signaling pathway; signal transduction; protein modification process; energy reserve metabolic process; regulation of vascular smooth muscle contraction | |
| CHRM5 | inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway; regulation of phosphatidylinositol dephosphorylation; transmission of nerve impulse; cell proliferation; G-protein coupled acetylcholine receptor signaling pathway; dopamine transport | |
| CHRNA1 | neuromuscular process; neuron homeostasis; musculoskeletal movement; skeletal muscle tissue growth; muscle cell homeostasis; regulation of membrane potential; regulation of action potential in neuron; neuromuscular synaptic transmission; synaptic transmission; signal transduction; ion transport; transport; skeletal muscle contraction; neuromuscular junction development | |
| CHRNA4 | sensory perception of pain; regulation of inhibitory postsynaptic membrane potential; membrane depolarization; cognition; neurological system process; regulation of membrane potential; B cell activation; behavioral response to nicotine; response to nicotine; regulation of dopamine secretion; locomotory behavior; regulation of action potential; response to hypoxia; DNA repair; ion transport; calcium ion transport; response to oxidative stress; signal transduction; synaptic transmission; synaptic transmission, cholinergic | |
| CHRNA6 | regulation of dopamine secretion; transport; synaptic transmission; ion transmembrane transport; membrane depolarization; signal transduction; cation transport | |
| CHRNA7 | positive regulation of cell proliferation; negative regulation of tumor necrosis factor production; response to nicotine; response to chemical stimulus; positive regulation of angiogenesis; cognition; synaptic transmission; memory; signal transduction; cellular calcium ion homeostasis; calcium ion transport; ion transport; response to hypoxia; activation of MAPK activity | |
| CHRNB1 | signal transduction; neurological system process; muscle fiber development; regulation of membrane potential; behavioral response to nicotine; ion transmembrane transport; neuromuscular synaptic transmission; synaptic transmission, cholinergic; muscle contraction; cation transport; postsynaptic membrane organization | |
| CHRNB2 | response to nicotine; behavioral response to nicotine; B cell activation; social behavior; regulation of dopamine metabolic process; membrane depolarization; ion transmembrane transport; positive regulation of dopamine secretion; positive regulation of synaptic transmission, dopaminergic; regulation of synaptic transmission, dopaminergic; positive regulation of B cell proliferation; response to cocaine; regulation of circadian sleep/wake cycle, REM sleep; regulation of circadian sleep/wake cycle, non-REM sleep; response to ethanol; negative regulation of action potential; regulation of dendrite morphogenesis; neurological system process; cognition; regulation of synapse assembly; synaptic transmission involved in micturition; calcium ion transport; lateral geniculate nucleus development; central nervous system projection neuron axonogenesis; conditioned taste aversion; response to hypoxia; ion transport; cation transport; smooth muscle contraction; signal transduction; synaptic transmission; synaptic transmis | |
| CHRNB3 | synaptic transmission, cholinergic; ion transport; synaptic transmission; transport; signal transduction | |
| CHRNB4 | regulation of neurotransmitter secretion; synaptic transmission involved in micturition; behavioral response to nicotine; locomotory behavior; synaptic transmission, cholinergic; synaptic transmission; signal transduction; regulation of smooth muscle contraction; ion transport; regulation of action potential | |
| CHRND | transport; cation transport; muscle contraction; signal transduction; synaptic transmission; ion transmembrane transport; regulation of membrane potential; skeletal muscle tissue growth; musculoskeletal movement; neuromuscular process | |
| CHRNG | ion transmembrane transport; regulation of membrane potential; synaptic transmission; signal transduction; muscle contraction; cation transport; transport | |
| CHST14 | carbohydrate biosynthetic process; dermatan sulfate proteoglycan metabolic process | |
| CHST15 | hexose biosynthetic process | |
| CHST2 | metabolic process; multicellular organismal development; inflammatory response; sulfur compound metabolic process; N-acetylglucosamine metabolic process; carbohydrate metabolic process | |
| CHST3 | chondroitin sulfate biosynthetic process; T cell homeostasis; positive regulation of cellular component movement; carbohydrate metabolic process; sulfur compound metabolic process; peripheral nervous system axon regeneration | |
| CHST4 | cellular component movement; protein sulfation; N-acetylglucosamine metabolic process; carbohydrate metabolic process; sulfur compound metabolic process; inflammatory response; immune response; cell adhesion; cell-cell signaling | |
| CHST5 | sulfur compound metabolic process; protein sulfation; N-acetylglucosamine metabolic process; carbohydrate metabolic process | |
| CHST6 | sulfur compound metabolic process; N-acetylglucosamine metabolic process; carbohydrate metabolic process; keratan sulfate biosynthetic process | |
| CHST8 | hormone biosynthetic process; proteoglycan biosynthetic process; carbohydrate biosynthetic process; sulfur compound metabolic process; central nervous system development | |
| CHST9 | hormone biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; carbohydrate biosynthetic process; metabolic process; sulfur compound metabolic process | |
| CHSY1 | negative regulation of ossification; response to nutrient levels; chondroitin sulfate biosynthetic process | |
| CHSY3 | - | |
| CHUK | toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; odontogenesis of dentin-containing tooth; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; T cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; mammary gland alveolus development; nucleotide-binding oligomerization domain containing signaling pathway; I-kappaB phosphorylation; osteoclast differentiation; morphogenesis of an epithelial sheet; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; protein phosphorylation; inflammatory response; immune response; | |
| CIART | - | |
| CIB2 | integrin-mediated signaling pathway | |
| CIB3 | - | |
| CIC | regulation of transcription, DNA-dependent | |
| CIDEB | DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis; apoptotic process | |
| CIITA | negative regulation of transcription, DNA-dependent; cytokine-mediated signaling pathway; positive regulation of MHC class II biosynthetic process; positive regulation of MHC class I biosynthetic process; response to interferon-gamma; negative regulation of collagen biosynthetic process; immune response; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to antibiotic; interferon-gamma-mediated signaling pathway | |
| CILP | negative regulation of insulin-like growth factor receptor signaling pathway | |
| CILP2 | - | |
| CIPC | - | |
| CIR1 | regulation of transcription, DNA-dependent; mRNA processing; RNA splicing; negative regulation of transcription, DNA-dependent | |
| CIRBP | response to UV; response to cold; negative regulation of translation; stress granule assembly; positive regulation of translation; mRNA stabilization | |
| CIT | cytokinesis; intracellular signal transduction; cell cycle; mitotic sister chromatid segregation; cell division; negative regulation of dendrite morphogenesis; mitosis; mitotic metaphase/anaphase transition; multicellular organismal development; spermatogenesis; nervous system development; dendrite development; cell differentiation; generation of neurons; cell cycle cytokinesis | |
| CKAP2 | positive regulation of transcription from RNA polymerase II promoter; cell cycle; cytokinesis after mitosis; apoptotic process | |
| CKAP2L | - | |
| CKAP5 | G2/M transition of mitotic cell cycle; RNA transport; establishment or maintenance of microtubule cytoskeleton polarity; spindle organization; mitotic cell cycle; M phase of mitotic cell cycle; mitotic prometaphase; centrosome organization; cell division | |
| CKMT2 | creatine metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; muscle contraction | |
| CLASRP | RNA splicing; mRNA processing | |
| CLCA1 | cellular response to hypoxia; chloride transport; calcium ion transport; ion transport; transport | |
| CLCA2 | cell adhesion; transport; chloride transport; ion transmembrane transport | |
| CLCA4 | chloride transport; transport | |
| CLCC1 | - | |
| CLCF1 | positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of immunoglobulin production; negative regulation of neuron apoptosis; positive regulation of isotype switching to IgE isotypes; positive regulation of astrocyte differentiation; negative regulation of apoptotic process; positive regulation of B cell proliferation; B cell differentiation; cytokine-mediated signaling pathway; positive regulation of cell proliferation; JAK-STAT cascade; cell surface receptor signaling pathway | |
| CLCN1 | transmembrane transport; neuronal action potential propagation; muscle contraction; chloride transport; ion transport; transport | |
| CLCN3 | transport; ion transport; chloride transport; regulation of pH; endosomal lumen acidification; transmembrane transport | |
| CLCN4 | transport; ion transport; chloride transport; transmembrane transport | |
| CLCN5 | transport; ion transport; chloride transport; endocytosis; excretion; transmembrane transport | |
| CLCN6 | transmembrane transport; ion transport; chloride transport; cell volume homeostasis; signal transduction | |
| CLCN7 | ion transport; chloride transport; response to pH; transmembrane transport; transport | |
| CLDN1 | cell adhesion; interspecies interaction between organisms; calcium-independent cell-cell adhesion | |
| CLDN11 | calcium-independent cell-cell adhesion; cell adhesion; axon ensheathment; spermatogenesis | |
| CLDN14 | tight junction assembly; cell-cell junction organization; cell junction assembly; calcium-independent cell-cell adhesion; protein complex assembly | |
| CLDN15 | tight junction assembly; cell-cell junction organization; cell junction assembly; calcium-independent cell-cell adhesion | |
| CLDN16 | cellular metal ion homeostasis; ion transport; excretion; magnesium ion transport; calcium-independent cell-cell adhesion | |
| CLDN2 | calcium-independent cell-cell adhesion | |
| CLDN3 | response to hypoxia; calcium-independent cell-cell adhesion | |
| CLDN5 | calcium-independent cell-cell adhesion | |
| CLDN7 | calcium-independent cell-cell adhesion | |
| CLDN8 | calcium-independent cell-cell adhesion | |
| CLDND1 | - | |
| CLEC10A | innate immune response; endocytosis | |
| CLEC12A | - | |
| CLEC12B | - | |
| CLEC14A | - | |
| CLEC1A | defense response; cell surface receptor signaling pathway | |
| CLEC2B | - | |
| CLEC4A | innate immune response; cell surface receptor signaling pathway; cell adhesion | |
| CLEC4E | immune response; positive regulation of cytokine secretion | |
| CLEC6A | positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; positive regulation of cytokine secretion; defense response to fungus | |
| CLECL1 | - | |
| CLGN | binding of sperm to zona pellucida; single fertilization; protein complex assembly; protein folding | |
| CLHC1 | - | |
| CLIC2 | signal transduction; transport; ion transport; chloride transport | |
| CLIC3 | signal transduction; chloride transport; ion transport | |
| CLIC4 | ion transport; cellular response to calcium ion; regulation of cytoskeleton organization; establishment or maintenance of apical/basal cell polarity; chloride transport; negative regulation of cell migration; keratinocyte differentiation; cell differentiation | |
| CLIC6 | ion transport | |
| CLIP1 | M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; microtubule bundle formation; mitosis; transport; positive regulation of microtubule polymerization | |
| CLIP2 | - | |
| CLIP4 | - | |
| CLK2 | negative regulation of gluconeogenesis; protein phosphorylation; response to ionizing radiation; regulation of RNA splicing; protein autophosphorylation | |
| CLLU1 | - | |
| CLMN | - | |
| CLMP | - | |
| CLOCK | cellular response to ionizing radiation; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; entrainment of circadian clock; photoperiodism; circadian rhythm; DNA damage checkpoint; regulation of transcription from RNA polymerase II promoter; signal transduction | |
| CLPB | cellular response to heat | |
| CLPTM1 | regulation of T cell differentiation in thymus; cell differentiation; multicellular organismal development | |
| CLPTM1L | apoptotic process | |
| CLRN1 | equilibrioception; sensory perception of light stimulus; response to stimulus; photoreceptor cell maintenance; sensory perception of sound | |
| CLRN3 | - | |
| CLSPN | DNA repair; G2/M transition DNA damage checkpoint; activation of protein kinase activity; DNA replication; DNA damage checkpoint; mitotic cell cycle DNA replication checkpoint; cell cycle checkpoint; apoptotic process; cellular component disassembly involved in apoptosis; cell cycle; peptidyl-serine phosphorylation | |
| CLSTN2 | homophilic cell adhesion; cell adhesion | |
| CLSTN3 | cell adhesion; homophilic cell adhesion | |
| CLTB | vesicle-mediated transport; intracellular protein transport | |
| CLTC | vesicle-mediated transport; cellular membrane organization; axon guidance; transferrin transport; epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; receptor internalization; mitosis; receptor-mediated endocytosis; post-Golgi vesicle-mediated transport; intracellular protein transport; nerve growth factor receptor signaling pathway | |
| CLUAP1 | - | |
| CLVS2 | lysosome organization | |
| CLYBL | cellular aromatic compound metabolic process | |
| CMA1 | interleukin-1 beta biosynthetic process; proteolysis; regulation of inflammatory response | |
| CMAS | lipopolysaccharide biosynthetic process | |
| CMBL | - | |
| CMPK2 | dTDP biosynthetic process; pyrimidine nucleotide biosynthetic process; cellular response to lipopolysaccharide | |
| CMTM1 | chemotaxis | |
| CMTR1 | mRNA capping; mRNA methylation | |
| CMTR2 | - | |
| CNBD2 | - | |
| CNBP | cholesterol biosynthetic process; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter | |
| CNDP1 | proteolysis; metabolic process | |
| CNFN | keratinization | |
| CNGA1 | transport; ion transport; visual perception; response to stimulus; transmembrane transport | |
| CNGA2 | response to stimulus; ion transmembrane transport; sensory perception of smell | |
| CNGA3 | transport; ion transport; cation transport; signal transduction; visual perception; ion transmembrane transport; retinal cone cell development; response to stimulus; transmembrane transport | |
| CNGB1 | visual perception; photoreceptor cell maintenance; ion transport; transport; phototransduction; sensory perception of smell; response to stimulus | |
| CNGB3 | transport; cation transport; signal transduction; visual perception; ion transmembrane transport; response to stimulus | |
| CNIH2 | synaptic transmission, glutamatergic; intracellular signal transduction; regulation of membrane potential; localization within membrane; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | |
| CNIH4 | intracellular signal transduction | |
| CNKSR1 | Ras protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; Rho protein signal transduction | |
| CNKSR2 | regulation of signal transduction | |
| CNKSR3 | negative regulation of ERK1 and ERK2 cascade; negative regulation of peptidyl-serine phosphorylation; positive regulation of sodium ion transport; regulation of signal transduction | |
| CNN1 | actomyosin structure organization; regulation of smooth muscle contraction | |
| CNN2 | actomyosin structure organization; cellular response to mechanical stimulus; negative regulation of cell migration; regulation of actin filament-based process; wound healing; regulation of cell proliferation; negative regulation of phagocytosis; hemopoiesis; positive regulation of gene expression; cytoskeleton organization | |
| CNN3 | smooth muscle contraction; actomyosin structure organization; negative regulation of ATPase activity | |
| CNNM3 | ion transport | |
| CNNM4 | response to stimulus; ion transport; biomineral tissue development; visual perception | |
| CNOT1 | nuclear-transcribed mRNA poly(A) tail shortening; regulation of transcription, DNA-dependent; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; RNA metabolic process | |
| CNOT10 | mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; RNA metabolic process; gene expression; nuclear-transcribed mRNA poly(A) tail shortening | |
| CNOT11 | - | |
| CNOT2 | mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; nuclear-transcribed mRNA poly(A) tail shortening; regulation of transcription from RNA polymerase II promoter; gene expression; RNA metabolic process | |
| CNOT4 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; nuclear-transcribed mRNA poly(A) tail shortening; regulation of transcription, DNA-dependent; gene expression; RNA metabolic process; protein autoubiquitination; mRNA metabolic process | |
| CNP | RNA metabolic process; synaptic transmission; axonogenesis; adult locomotory behavior; cyclic nucleotide catabolic process; response to toxin; microtubule cytoskeleton organization | |
| CNPPD1 | regulation of cyclin-dependent protein kinase activity | |
| CNPY2 | - | |
| CNPY3 | innate immune response | |
| CNPY4 | - | |
| CNR1 | behavior; response to nutrient; aging; positive regulation of fever generation; spermatogenesis; memory; positive regulation of neuron projection development; regulation of lipid metabolic process; sensory perception of pain; G-protein signaling, coupled to cyclic nucleotide second messenger; regulation of penile erection; regulation of feeding behavior; maternal process involved in female pregnancy; regulation of synaptic transmission, glutamatergic; negative regulation of nitric-oxide synthase activity; regulation of insulin secretion; positive regulation of blood pressure; negative regulation of blood pressure; negative regulation of action potential; response to ethanol; response to morphine; negative regulation of ion transport; positive regulation of apoptotic process; response to cocaine; response to nicotine; negative regulation of dopamine secretion; negative regulation of mast cell activation; response to lipopolysaccharide; regulation of synaptic transmission, GABAergic; negative regulation of fatt | |
| CNR2 | response to amphetamine; immune response; G-protein signaling, coupled to cyclic nucleotide second messenger; sensory perception of pain; negative regulation of synaptic transmission, GABAergic; response to lipopolysaccharide; negative regulation of mast cell activation; negative regulation of action potential; negative regulation of inflammatory response; negative regulation of nitric-oxide synthase activity; behavior | |
| CNRIP1 | - | |
| CNST | positive regulation of Golgi to plasma membrane protein transport; negative regulation of phosphatase activity | |
| CNTF | regulation of retinal cell programmed cell death; negative regulation of photoreceptor cell differentiation; positive regulation of JAK-STAT cascade; neuroprotection; negative regulation of neuron apoptosis; positive regulation of MAPK cascade; positive regulation of tyrosine phosphorylation of Stat3 protein; growth; positive regulation of cell growth; cell differentiation; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of cell proliferation; nervous system development; multicellular organismal development; signal transduction; astrocyte activation; muscle organ morphogenesis; neuron development; positive regulation of axon regeneration; regulation of resting membrane potential; membrane hyperpolarization; ciliary neurotrophic factor-mediated signaling pathway; positive regulation of hormone secretion | |
| CNTFR | signal transduction; ciliary neurotrophic factor-mediated signaling pathway; skeletal muscle organ development; negative regulation of neuron apoptosis; positive regulation of cell proliferation; sex differentiation; nervous system development; brainstem development; suckling behavior | |
| CNTLN | - | |
| CNTN1 | cell adhesion; Notch signaling pathway; axon guidance | |
| CNTN2 | regulation of axon diameter; cell-matrix adhesion; neuron migration; learning; adult walking behavior; regulation of cell morphogenesis involved in differentiation; positive regulation of protein processing; central nervous system myelination; cerebral cortex GABAergic interneuron migration; neuron projection development; receptor internalization; cellular protein localization; clustering of voltage-gated potassium channels; negative regulation of neuron differentiation; regulation of neuronal synaptic plasticity; regulation of astrocyte differentiation; positive regulation of adenosine receptor signaling pathway; establishment of protein localization to juxtaparanode region of axon; cell adhesion; microtubule cytoskeleton organization; axon guidance; axonal fasciculation | |
| CNTN3 | nervous system development; cell adhesion | |
| CNTN4 | axonal fasciculation; axonogenesis; nervous system development; neuron cell-cell adhesion; cell adhesion; regulation of synaptic plasticity; negative regulation of neuron differentiation; neuron projection development; brain development; axon guidance | |
| CNTN6 | cell adhesion; Notch signaling pathway; central nervous system development; axon guidance | |
| CNTNAP1 | neuromuscular process controlling balance; neuromuscular process controlling posture; neuron projection morphogenesis; paranodal junction assembly; axon cargo transport; axon guidance; signal transduction; cell adhesion; cytoskeleton organization; protein localization to paranode region of axon | |
| CNTNAP2 | cell adhesion; signal transduction; behavior; brain development; protein localization to juxtaparanode region of axon; thalamus development; limbic system development; cerebral cortex development; neuron projection development; cellular protein localization; clustering of voltage-gated potassium channels; superior temporal gyrus development; vocalization behavior; striatum development; neuron recognition; transmission of nerve impulse | |
| CNTRL | G2/M transition of mitotic cell cycle; cell division; mitotic cell cycle | |
| CNTROB | centrosome separation; cytokinesis; cell cycle; centriole replication | |
| COA4 | - | |
| COA6 | - | |
| COA7 | - | |
| COASY | small molecule metabolic process; coenzyme A biosynthetic process; vitamin metabolic process; water-soluble vitamin metabolic process; pantothenate metabolic process; biosynthetic process; coenzyme biosynthetic process | |
| COBL | neural tube closure | |
| COBLL1 | - | |
| COCH | sensory perception of sound | |
| COG1 | protein transport; Golgi organization; intra-Golgi vesicle-mediated transport | |
| COG2 | protein glycosylation; intracellular protein transport; protein transport; intra-Golgi vesicle-mediated transport; Golgi organization; oligosaccharide biosynthetic process | |
| COG4 | retrograde vesicle-mediated transport, Golgi to ER; Golgi organization; protein transport; Golgi vesicle prefusion complex stabilization | |
| COG5 | protein transport; intra-Golgi vesicle-mediated transport | |
| COG6 | intra-Golgi vesicle-mediated transport; protein transport | |
| COG7 | protein stabilization; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; protein glycosylation; protein localization to organelle; protein localization in Golgi apparatus | |
| COG8 | protein transport | |
| COL10A1 | skeletal system development | |
| COL11A1 | cartilage condensation; extracellular matrix organization; ventricular cardiac muscle tissue morphogenesis; detection of mechanical stimulus involved in sensory perception of sound; embryonic skeletal system morphogenesis; cell adhesion; visual perception; proteoglycan metabolic process; heart morphogenesis; chondrocyte development; ossification; collagen fibril organization; inner ear morphogenesis; sensory perception of sound | |
| COL12A1 | skeletal system development; cell adhesion; collagen fibril organization | |
| COL14A1 | extracellular matrix organization; cell-cell adhesion; collagen fibril organization | |
| COL15A1 | signal transduction; cell adhesion; multicellular organismal development; cell differentiation; angiogenesis | |
| COL16A1 | cell adhesion; integrin-mediated signaling pathway; female pregnancy; cellular response to amino acid stimulus | |
| COL17A1 | hemidesmosome assembly; cell junction assembly; epidermis development; cell-matrix adhesion | |
| COL18A1 | visual perception; cell adhesion; negative regulation of cell proliferation; organ morphogenesis | |
| COL19A1 | skeletal system development; cell adhesion; multicellular organismal development; muscle organ development; skeletal muscle tissue development; cell-cell adhesion; cell differentiation; extracellular matrix organization | |
| COL1A1 | protein localization to nucleus; collagen biosynthetic process; platelet activation; response to corticosteroid stimulus; positive regulation of cell migration; collagen fibril organization; positive regulation of canonical Wnt receptor signaling pathway; tooth mineralization; response to hydrogen peroxide; response to peptide hormone stimulus; skin morphogenesis; positive regulation of transcription, DNA-dependent; embryonic skeletal system development; leukocyte migration; response to cAMP; face morphogenesis; bone trabecula formation; cartilage development involved in endochondral bone morphogenesis; protein heterotrimerization; cellular response to amino acid stimulus; cellular response to mechanical stimulus; cellular response to retinoic acid; cellular response to growth factor stimulus; negative regulation of cell-substrate adhesion; skeletal system development; blood vessel development; osteoblast differentiation; intramembranous ossification; endochondral ossification; axon guidance; response to nutr | |
| COL22A1 | cell adhesion | |
| COL23A1 | protein homotrimerization | |
| COL24A1 | cell adhesion | |
| COL25A1 | - | |
| COL27A1 | cell adhesion | |
| COL28A1 | cell adhesion | |
| COL2A1 | heart morphogenesis; chondrocyte differentiation; notochord development; endochondral ossification; proteoglycan metabolic process; axon guidance; central nervous system development; visual perception; sensory perception of sound; regulation of gene expression; collagen fibril organization; inner ear morphogenesis; tissue homeostasis; ossification; cartilage condensation; skeletal system development; otic vesicle development; cartilage development involved in endochondral bone morphogenesis; bone development; embryonic skeletal joint morphogenesis; limb bud formation; palate development; cartilage development; negative regulation of apoptotic process | |
| COL3A1 | platelet activation; cellular response to amino acid stimulus; negative regulation of immune response; digestive tract development; skin development; fibril organization; wound healing; response to cytokine stimulus; collagen biosynthetic process; collagen fibril organization; peptide cross-linking; response to radiation; heart development; axon guidance; integrin-mediated signaling pathway; transforming growth factor beta receptor signaling pathway; cell-matrix adhesion; blood vessel development; skeletal system development | |
| COL4A1 | axon guidance; angiogenesis; neuromuscular junction development; epithelial cell differentiation; cellular response to amino acid stimulus | |
| COL4A2 | transcription, DNA-dependent; axon guidance; negative regulation of angiogenesis; extracellular matrix organization; cellular response to transforming growth factor beta stimulus | |
| COL4A3 | activation of cysteine-type endopeptidase activity involved in apoptotic process; glomerular basement membrane development; induction of apoptosis; cell adhesion; cell surface receptor signaling pathway; axon guidance; sensory perception of sound; blood circulation; cell proliferation; negative regulation of cell proliferation; response to glucose stimulus; negative regulation of angiogenesis | |
| COL4A3BP | cell proliferation; transport; sphingolipid biosynthetic process; ceramide metabolic process; sphingolipid metabolic process; response to endoplasmic reticulum stress; protein phosphorylation; ER to Golgi ceramide transport; small molecule metabolic process; lipid homeostasis; mitochondrion morphogenesis; lipid transport; heart morphogenesis; in utero embryonic development; cell morphogenesis; muscle contraction; immune response; endoplasmic reticulum organization; signal transduction | |
| COL4A4 | axon guidance; glomerular basement membrane development | |
| COL4A5 | axon guidance | |
| COL4A6 | cell adhesion; extracellular matrix organization; cellular response to amino acid stimulus | |
| COL5A1 | cell migration; blood vessel development; heart morphogenesis; cell adhesion; axon guidance; collagen fibril organization; collagen biosynthetic process; wound healing, spreading of epidermal cells; fibril organization; skin development; integrin biosynthetic process; eye morphogenesis; regulation of cellular component organization | |
| COL5A2 | collagen fibril organization; axon guidance; skeletal system development; skin development; eye morphogenesis; cellular response to amino acid stimulus | |
| COL5A3 | collagen fibril organization; skin development; cell adhesion; cell-matrix adhesion | |
| COL6A1 | cell adhesion; axon guidance; protein heterotrimerization; cellular response to amino acid stimulus | |
| COL6A2 | response to glucose stimulus; protein heterotrimerization; extracellular matrix organization; cell-cell adhesion; axon guidance | |
| COL6A3 | cell adhesion; axon guidance; muscle organ development; response to glucose stimulus | |
| COL7A1 | cell adhesion; epidermis development | |
| COL8A2 | epithelial cell proliferation; camera-type eye morphogenesis; extracellular matrix organization; cell-cell adhesion; angiogenesis | |
| COL9A1 | organ morphogenesis; axon guidance; cell adhesion; growth plate cartilage development; chondrocyte differentiation; tissue homeostasis | |
| COL9A2 | skeletal system development; axon guidance | |
| COLEC10 | - | |
| COLGALT2 | - | |
| COLQ | neurotransmitter catabolic process; acetylcholine catabolic process in synaptic cleft; asymmetric protein localization | |
| COMMD9 | - | |
| COMP | anti-apoptosis; skeletal system development; growth plate cartilage development; apoptotic process; cell adhesion; organ morphogenesis; limb development | |
| COPA | vesicle-mediated transport; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; cellular membrane organization; pancreatic juice secretion; COPI coating of Golgi vesicle | |
| COPB1 | vesicle-mediated transport; COPI coating of Golgi vesicle; interspecies interaction between organisms; cellular membrane organization; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport | |
| COPB2 | intra-Golgi vesicle-mediated transport; intracellular protein transport; COPI coating of Golgi vesicle; vesicle-mediated transport; cellular membrane organization; retrograde vesicle-mediated transport, Golgi to ER | |
| COPG1 | COPI coating of Golgi vesicle; vesicle-mediated transport; cellular membrane organization; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport | |
| COPS2 | transcription from RNA polymerase II promoter; signal transduction; cullin deneddylation | |
| COPS3 | cullin deneddylation; response to light stimulus; in utero embryonic development; signal transduction | |
| COPS4 | cullin deneddylation | |
| COPS5 | proteolysis; regulation of cell cycle; regulation of JNK cascade; positive regulation of transcription from RNA polymerase II promoter; cullin deneddylation; translational initiation; translation; transcription from RNA polymerase II promoter; protein deneddylation | |
| COPS6 | interspecies interaction between organisms; cullin deneddylation | |
| COPS7A | cullin deneddylation | |
| COPS7B | cullin deneddylation | |
| COPS8 | cullin deneddylation | |
| COPZ1 | intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; intra-Golgi vesicle-mediated transport; cellular membrane organization; vesicle-mediated transport; COPI coating of Golgi vesicle | |
| COQ10A | - | |
| COQ10B | - | |
| COQ3 | metabolic process; ubiquinone biosynthetic process; glycerol metabolic process | |
| COQ6 | ubiquinone biosynthetic process | |
| CORIN | regulation of systemic arterial blood pressure by atrial natriuretic peptide; proteolysis; peptide hormone processing | |
| CORO1A | positive regulation of cell migration; cellular component movement; phagocytosis; actin filament organization; calcium ion transport; phagolysosome assembly; regulation of cell shape; actin cytoskeleton organization; homeostasis of number of cells within a tissue; leukocyte chemotaxis; regulation of actin filament polymerization; cell-substrate adhesion; uropod organization; response to cytokine stimulus; positive regulation of T cell proliferation; T cell homeostasis; innate immune response; negative regulation of actin nucleation; positive chemotaxis | |
| CORO1B | actin cytoskeleton organization | |
| CORO2A | intracellular signal transduction; actin cytoskeleton organization | |
| CORO2B | actin cytoskeleton organization | |
| CORO6 | actin cytoskeleton organization | |
| COX15 | mitochondrial electron transport, cytochrome c to oxygen; heme a biosynthetic process; respiratory gaseous exchange; respiratory chain complex IV assembly; cellular respiration; oxidation-reduction process | |
| COX7B2 | - | |
| COX8C | - | |
| CP | transmembrane transport; cellular iron ion homeostasis; copper ion transport; ion transport | |
| CPA1 | proteolysis | |
| CPA2 | vacuolar protein catabolic process; proteolysis | |
| CPA5 | metabolic process; proteolysis | |
| CPA6 | proteolysis | |
| CPAMD8 | - | |
| CPB1 | proteolysis | |
| CPB2 | negative regulation of fibrinolysis; response to drug; response to heat; metabolic process; blood coagulation; proteolysis | |
| CPD | proteolysis; cellular response to interleukin-2 | |
| CPE | cardiac left ventricle morphogenesis; protein modification process; proteolysis; neuropeptide signaling pathway; metabolic process; insulin processing; protein localization in membrane | |
| CPEB1 | mRNA processing; regulation of translation | |
| CPEB2 | regulation of translation | |
| CPEB3 | - | |
| CPED1 | - | |
| CPN1 | proteolysis; response to glucocorticoid stimulus; metabolic process | |
| CPN2 | regulation of catalytic activity; protein stabilization | |
| CPNE1 | vesicle-mediated transport; lipid metabolic process | |
| CPNE2 | - | |
| CPNE3 | lipid metabolic process; vesicle-mediated transport | |
| CPNE4 | - | |
| CPNE5 | - | |
| CPNE7 | transport; lipid metabolic process | |
| CPNE8 | - | |
| CPO | proteolysis | |
| CPPED1 | - | |
| CPQ | tissue regeneration; proteolysis; peptide metabolic process | |
| CPS1 | small molecule metabolic process; anion homeostasis; cellular response to fibroblast growth factor stimulus; positive regulation of vasodilation; nitric oxide metabolic process; response to steroid hormone stimulus; homocysteine metabolic process; response to growth hormone stimulus; hepatocyte differentiation; carbamoyl phosphate biosynthetic process; cellular response to cAMP; cellular response to glucagon stimulus; cellular response to oleic acid; response to dexamethasone stimulus; response to starvation; response to amino acid stimulus; glycogen catabolic process; glutamine catabolic process; nitrogen compound metabolic process; midgut development; response to toxin; response to zinc ion; citrulline biosynthetic process; urea cycle; triglyceride catabolic process; response to food; response to lipopolysaccharide; cellular nitrogen compound metabolic process; response to drug | |
| CPSF1 | mRNA cleavage; gene expression; RNA splicing; mRNA export from nucleus; mRNA processing; mRNA polyadenylation; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; termination of RNA polymerase II transcription; mRNA 3'-end processing | |
| CPSF2 | transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; gene expression; mRNA export from nucleus; mRNA 3'-end processing; RNA splicing; histone mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription | |
| CPSF3 | RNA splicing; mRNA polyadenylation; gene expression; mRNA export from nucleus; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; termination of RNA polymerase II transcription; mRNA processing; histone mRNA 3'-end processing; mRNA 3'-end processing; mRNA cleavage | |
| CPSF4 | mRNA processing; interspecies interaction between organisms; virus-host interaction; modulation by virus of host cellular process; viral infectious cycle; modification by virus of host mRNA processing | |
| CPSF6 | mRNA polyadenylation; protein tetramerization; mRNA processing | |
| CPSF7 | termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA processing; RNA splicing; gene expression; mRNA 3'-end processing; protein tetramerization | |
| CPT1A | protein homooligomerization; regulation of insulin secretion; regulation of fatty acid oxidation; small molecule metabolic process; cellular lipid metabolic process; eating behavior; response to drug; response to organic cyclic compound; carnitine shuttle; transport; triglyceride metabolic process; fatty acid beta-oxidation; glucose metabolic process; long-chain fatty acid metabolic process; positive regulation of fatty acid beta-oxidation | |
| CPT1B | fatty acid beta-oxidation; regulation of fatty acid oxidation; small molecule metabolic process; cellular lipid metabolic process; carnitine shuttle; transport; fatty acid metabolic process | |
| CPT1C | carnitine metabolic process; lipid metabolic process; fatty acid metabolic process | |
| CPT2 | fatty acid metabolic process; regulation of fatty acid oxidation; small molecule metabolic process; cellular lipid metabolic process; carnitine shuttle; transport; fatty acid beta-oxidation | |
| CPTP | - | |
| CPXCR1 | - | |
| CPXM1 | cell adhesion; proteolysis | |
| CPXM2 | cell adhesion; proteolysis | |
| CPZ | proteolysis; Wnt receptor signaling pathway | |
| CR2 | complement receptor mediated signaling pathway; innate immune response; immune response; complement activation, classical pathway | |
| CRACR2B | store-operated calcium entry | |
| CRAT | small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; transport; fatty acid metabolic process | |
| CRB1 | cellular membrane organization; eye photoreceptor cell development; cell-cell signaling; establishment or maintenance of cell polarity | |
| CRB2 | - | |
| CRBN | negative regulation of protein homooligomerization; negative regulation of ion transmembrane transport; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; proteolysis; positive regulation of protein homodimerization activity | |
| CREB3 | transcription, DNA-dependent; positive regulation of calcium ion transport; chemotaxis; reactivation of latent virus; positive regulation of cell migration; induction of positive chemotaxis; regulation of cell proliferation; positive regulation of transcription, DNA-dependent; negative regulation of cell cycle; interspecies interaction between organisms | |
| CREB3L3 | response to unfolded protein | |
| CREB5 | transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent | |
| CREBBP | histone acetylation; N-terminal peptidyl-lysine acetylation; germ-line stem cell maintenance; regulation of S phase; homeostatic process; embryonic digit morphogenesis; response to hypoxia; cellular lipid metabolic process; small molecule metabolic process; interspecies interaction between organisms; innate immune response; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of smoothened signaling pathway; cell proliferation; Notch signaling pathway; signal transduction; protein complex assembly; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; gene expression | |
| CREBRF | - | |
| CREBZF | transcription, DNA-dependent; regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of gene expression, epigenetic; response to virus | |
| CREM | cell differentiation; spermatogenesis; multicellular organismal development; signal transduction; regulation of transcription, DNA-dependent | |
| CRHR2 | G-protein signaling, coupled to cAMP nucleotide second messenger; cellular response to corticotropin-releasing hormone stimulus | |
| CRIM1 | nervous system development; regulation of cell growth; insulin-like growth factor receptor signaling pathway | |
| CRIPAK | negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of protein kinase activity; response to estrogen stimulus; regulation of cytoskeleton organization | |
| CRIPT | establishment of protein localization; cytoplasmic microtubule organization | |
| CRISP2 | - | |
| CRISPLD2 | - | |
| CRMP1 | nucleobase-containing compound metabolic process; pyrimidine base catabolic process; nervous system development; axon guidance | |
| CRNKL1 | RNA processing; RNA splicing; nuclear mRNA splicing, via spliceosome; spliceosome assembly | |
| CROCC | centrosome organization; cell projection organization; cell cycle; protein localization | |
| CROT | cellular lipid metabolic process; small molecule metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; transport; fatty acid beta-oxidation; fatty acid metabolic process | |
| CRTAC1 | - | |
| CRTAM | detection of tumor cell; T cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of cytokine secretion; regulation of immune response; detection of stimulus; activated T cell proliferation | |
| CRTC1 | regulation of transcription, DNA-dependent; positive regulation of CREB transcription factor activity; interspecies interaction between organisms; positive regulation of transcription from RNA polymerase II promoter; protein homotetramerization | |
| CRTC2 | gluconeogenesis; regulation of transcription, DNA-dependent; positive regulation of CREB transcription factor activity; protein homotetramerization; interspecies interaction between organisms; glucose homeostasis | |
| CRTC3 | regulation of transcription, DNA-dependent; positive regulation of CREB transcription factor activity; protein homotetramerization; interspecies interaction between organisms | |
| CRX | visual perception; regulation of transcription, DNA-dependent; multicellular organismal development; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; response to stimulus; retina development in camera-type eye | |
| CRY2 | regulation of circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; photoreactive repair; DNA repair; regulation of transcription, DNA-dependent; protein import into nucleus; blue light signaling pathway; protein-chromophore linkage; response to stimulus | |
| CRYAB | protein folding; protein homooligomerization; negative regulation of intracellular transport; muscle contraction; anti-apoptosis | |
| CRYBA2 | - | |
| CRYGA | eye development; visual perception; lens development in camera-type eye | |
| CRYGD | visual perception; cellular response to reactive oxygen species; response to stimulus | |
| CRYGS | morphogenesis of an epithelium; lens development in camera-type eye | |
| CRYL1 | fatty acid metabolic process | |
| CRYZ | visual perception; xenobiotic catabolic process; protein homotetramerization | |
| CS | cellular carbohydrate metabolic process; small molecule metabolic process; citrate metabolic process; tricarboxylic acid cycle; acetyl-CoA metabolic process; carbohydrate metabolic process; oxaloacetate metabolic process | |
| CSDC2 | regulation of transcription, DNA-dependent; mRNA processing; histone mRNA 3'-end processing | |
| CSDE1 | male gonad development; regulation of transcription, DNA-dependent | |
| CSF1 | innate immune response; homeostasis of number of cells within a tissue; branching involved in mammary gland duct morphogenesis; mammary gland fat development; mammary duct terminal end bud growth; positive regulation of protein kinase activity; positive regulation of cell-matrix adhesion; developmental process involved in reproduction; inflammatory response; cell proliferation; positive regulation of cell proliferation; positive regulation of gene expression; regulation of macrophage derived foam cell differentiation; positive regulation of macrophage derived foam cell differentiation; hemopoiesis; cell differentiation; macrophage differentiation; regulation of ossification; osteoclast differentiation; positive regulation of cell migration; positive regulation of cellular protein metabolic process; positive regulation of mononuclear cell proliferation; positive regulation of multicellular organism growth; monocyte activation; odontogenesis; positive regulation of odontogenesis of dentin-containing tooth; posi | |
| CSF1R | positive regulation of protein tyrosine kinase activity; positive regulation of ERK1 and ERK2 cascade; cellular response to cytokine stimulus; positive regulation of protein serine/threonine kinase activity; positive regulation of chemokine secretion; positive regulation of cell motility; regulation of actin cytoskeleton reorganization; ruffle organization; regulation of cell shape; positive regulation of protein phosphorylation; mammary gland duct morphogenesis; inflammatory response; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; multicellular organismal development; cell proliferation; positive regulation of cell proliferation; phosphatidylinositol-mediated signaling; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; hemopoiesis; monocyte differentiation; macrophage differentiation; osteoclast differentiation; positive regulation of cell migration; cellular response to macrophage colony-stimulating factor stimulus; protein autophosphorylation; p | |
| CSF2RB | signal transduction; respiratory gaseous exchange; cellular response to interleukin-3; interleukin-5-mediated signaling pathway | |
| CSF3 | immune response; multicellular organismal development; positive regulation of cell proliferation; cytokine-mediated signaling pathway; granulocyte differentiation | |
| CSF3R | signal transduction; cell adhesion; defense response | |
| CSGALNACT2 | proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process | |
| CSK | protein phosphorylation; epidermal growth factor receptor signaling pathway; blood coagulation; negative regulation of cell proliferation; platelet activation; T cell costimulation; T cell receptor signaling pathway; peptidyl-tyrosine dephosphorylation | |
| CSMD2 | - | |
| CSMD3 | - | |
| CSN2 | negative regulation of catalytic activity; calcium ion transport | |
| CSN3 | lactation | |
| CSNK1D | signal transduction; positive regulation of canonical Wnt receptor signaling pathway; spindle assembly; rhythmic process; regulation of circadian rhythm; circadian regulation of gene expression; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; Wnt receptor signaling pathway; protein phosphorylation; DNA repair; positive regulation of protein phosphorylation; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| CSNK1E | negative regulation of Wnt receptor signaling pathway; cellular protein localization; G2/M transition of mitotic cell cycle; mitotic cell cycle; DNA repair; protein phosphorylation; signal transduction; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of canonical Wnt receptor signaling pathway | |
| CSNK1G2 | sphingolipid biosynthetic process; small molecule metabolic process; protein autophosphorylation; Wnt receptor signaling pathway; signal transduction; sphingolipid metabolic process; protein phosphorylation | |
| CSNK2A2 | mitotic cell cycle spindle checkpoint; regulation of transcription, DNA-dependent; apoptotic process; axon guidance; Wnt receptor signaling pathway; regulation of cell cycle | |
| CSPG4 | multicellular organismal development; angiogenesis; neuron remodeling; cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; tissue remodeling; neuron fate commitment; intracellular signal transduction | |
| CSPP1 | positive regulation of cell division; positive regulation of cell cycle cytokinesis | |
| CSRNP3 | negative regulation of phosphatase activity; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter | |
| CST9L | - | |
| CSTF2T | mRNA processing | |
| CSTF3 | gene expression; mRNA 3'-end processing; RNA splicing; mRNA processing; RNA processing; mRNA polyadenylation; termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA cleavage | |
| CSTL1 | - | |
| CTAGE5 | positive regulation of catalytic activity | |
| CTBP1 | protein phosphorylation; negative regulation of cell proliferation; viral genome replication; cell differentiation; positive regulation of histone deacetylation; regulation of transcription by chromatin organization; negative regulation of histone acetylation; interspecies interaction between organisms; negative regulation of transcription, DNA-dependent; white fat cell differentiation; regulation of cell cycle; oxidation-reduction process; negative regulation of histone H4 acetylation; negative regulation of transcription from RNA polymerase II promoter | |
| CTBP2 | negative regulation of cell proliferation; viral genome replication; cell differentiation; negative regulation of transcription, DNA-dependent; white fat cell differentiation; oxidation-reduction process | |
| CTBS | carbohydrate metabolic process; chitin catabolic process; oligosaccharide catabolic process | |
| CTC1 | positive regulation of DNA replication; telomere maintenance | |
| CTCF | positive regulation of gene expression; chromosome segregation; chromatin modification; nucleosome positioning; regulation of histone methylation; maintenance of DNA methylation; regulation of histone acetylation; regulation of gene expression, epigenetic; regulation of molecular function, epigenetic; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of gene expression by genetic imprinting; regulation of centromeric sister chromatid cohesion | |
| CTCFL | cell cycle; regulation of gene expression by genetic imprinting; positive regulation of gene expression; chromatin modification; histone methylation; DNA methylation involved in gamete generation; positive regulation of transcription, DNA-dependent; regulation of histone H3-K4 methylation | |
| CTDNEP1 | nuclear envelope organization; positive regulation of triglyceride biosynthetic process; protein localization to nucleus; protein dephosphorylation | |
| CTDSP1 | negative regulation of neuron differentiation; regulation of transcription from RNA polymerase II promoter; protein dephosphorylation; negative regulation of neurogenesis | |
| CTDSPL2 | - | |
| CTGF | positive regulation of cell death; organ senescence; response to fatty acid; positive regulation of ERK1 and ERK2 cascade; positive regulation of G0 to G1 transition; extracellular matrix constituent secretion; positive regulation of cardiac muscle contraction; response to glucose stimulus; cytosolic calcium ion transport; positive regulation of stress fiber assembly; response to mineralocorticoid stimulus; positive regulation of gene expression; positive regulation of cell activation; response to organic cyclic compound; lung development; response to estradiol stimulus; positive regulation of collagen biosynthetic process; response to anoxia; intracellular signal transduction; response to amino acid stimulus; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to peptide hormone stimulus; cellular lipid metabolic process; small molecule metabolic process; positive regulation of cell differentiation; positive regulation of JNK cascade; positive regulation of cel | |
| CTH | small molecule metabolic process; negative regulation of cell proliferation; glutathione metabolic process; cysteine metabolic process; sulfur amino acid catabolic process; cellular amino acid biosynthetic process; sulfur amino acid metabolic process; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; cysteine biosynthetic process; transsulfuration; negative regulation of cell growth; cellular nitrogen compound metabolic process; protein homotetramerization; hydrogen sulfide biosynthetic process | |
| CTHRC1 | cell migration; positive regulation of protein binding; Wnt receptor signaling pathway, planar cell polarity pathway; inner ear receptor stereocilium organization; negative regulation of canonical Wnt receptor signaling pathway; cochlea morphogenesis; establishment of planar polarity involved in neural tube closure | |
| CTNNA1 | negative regulation of apoptotic process; male gonad development; aging; negative regulation of neuroblast proliferation; establishment or maintenance of cell polarity; response to organic cyclic compound; gap junction assembly; axon regeneration; cell junction assembly; adherens junction organization; regulation of cell proliferation; odontogenesis of dentin-containing tooth; cell adhesion; ovarian follicle development; cellular response to indole-3-methanol; positive regulation of muscle cell differentiation; positive regulation of smoothened signaling pathway; cell-cell junction organization; response to estrogen stimulus; apical junction assembly; muscle cell differentiation | |
| CTNNA2 | dendrite morphogenesis; multicellular organismal development; axonogenesis; cell-cell adhesion; radial glia guided migration of Purkinje cell; muscle cell differentiation; prepulse inhibition; regulation of synapse structural plasticity; positive regulation of muscle cell differentiation; brain morphogenesis | |
| CTNNA3 | cell-cell adhesion | |
| CTNNAL1 | Rho protein signal transduction; cell adhesion | |
| CTNNB1 | negative regulation of transcription, DNA-dependent; positive regulation of osteoblast differentiation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to cadmium ion; regulation of fibroblast proliferation; determination of dorsal/ventral asymmetry; cell maturation; synaptic vesicle transport; thymus development; oocyte development; embryonic foregut morphogenesis; regulation of smooth muscle cell proliferation; negative regulation of oligodendrocyte differentiation; positive regulation of anti-apoptosis; regulation of angiogenesis; positive regulation of fibroblast growth factor receptor signaling pathway; negative regulation of osteoclast differentiation; canonical Wnt receptor signaling pathway; positive regulation of endothelial cell differentiation; bone resorption; myoblast differentiation; canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis; canonical Wnt receptor signaling pathway inv | |
| CTNNBL1 | somatic diversification of immunoglobulins; positive regulation of apoptotic process | |
| CTNND2 | morphogenesis of a branching structure; regulation of transcription, DNA-dependent; cell adhesion; neuron cell-cell adhesion; regulation of synaptic plasticity; learning; multicellular organismal development; signal transduction | |
| CTPS1 | small molecule metabolic process; nucleobase-containing small molecule metabolic process; nucleobase-containing compound metabolic process; pyrimidine nucleotide biosynthetic process; CTP biosynthetic process; glutamine metabolic process; nucleobase-containing small molecule interconversion; response to drug | |
| CTPS2 | pyrimidine nucleotide metabolic process; glutamine metabolic process; pyrimidine nucleotide biosynthetic process; nucleobase-containing small molecule interconversion; small molecule metabolic process; nucleobase-containing small molecule metabolic process | |
| CTR9 | histone H2B ubiquitination; histone monoubiquitination | |
| CTSA | glycosphingolipid metabolic process; proteolysis; sphingolipid metabolic process; small molecule metabolic process; positive regulation of catalytic activity; intracellular protein transport | |
| CTSB | response to glucose stimulus; proteolysis; autophagy; skeletal muscle tissue development; response to wounding; response to mechanical stimulus; response to organic cyclic compound; response to amine stimulus; regulation of apoptotic process; response to peptide hormone stimulus; response to ethanol; regulation of catalytic activity; negative regulation of cell death; response to interleukin-4; cellular response to thyroid hormone stimulus | |
| CTSD | cell death; proteolysis | |
| CTSE | digestion; proteolysis; antigen processing and presentation of exogenous peptide antigen via MHC class II | |
| CTSW | proteolysis; immune response | |
| CTTN | - | |
| CTTNBP2 | brain development | |
| CTTNBP2NL | - | |
| CTU2 | tRNA thio-modification; tRNA processing; tRNA wobble uridine modification | |
| CUBN | in utero embryonic development; tissue homeostasis; lipid metabolic process; receptor-mediated endocytosis; lipoprotein metabolic process; protein homotrimerization; lipoprotein transport; response to nutrient; steroid metabolic process; cholesterol metabolic process; cobalamin transport; small molecule metabolic process; vitamin D metabolic process; hemoglobin import | |
| CUL2 | interspecies interaction between organisms; protein catabolic process; induction of apoptosis by intracellular signals; negative regulation of cell proliferation; cell cycle arrest; ubiquitin-dependent protein catabolic process; G1/S transition of mitotic cell cycle | |
| CUL3 | positive regulation of cell proliferation; cyclin catabolic process; anaphase; proteasomal ubiquitin-dependent protein catabolic process; G1/S transition of mitotic cell cycle; mitotic anaphase; stress fiber assembly; cytokinesis; in utero embryonic development; trophectodermal cellular morphogenesis; cell morphogenesis; induction of apoptosis by intracellular signals; Wnt receptor signaling pathway; cell cycle arrest; gastrulation; negative regulation of Rho protein signal transduction; protein ubiquitination; cell migration | |
| CUL4A | ubiquitin-dependent protein catabolic process; cell cycle arrest; DNA repair; G1/S transition of mitotic cell cycle; regulation of mitotic cell cycle; negative regulation of cell proliferation; induction of apoptosis by intracellular signals; interspecies interaction between organisms; positive regulation of S phase of mitotic cell cycle; regulation of protein metabolic process | |
| CUL4B | DNA repair; ubiquitin-dependent protein catabolic process; cell cycle | |
| CUL5 | cell proliferation; cell cycle arrest; response to osmotic stress; interspecies interaction between organisms; ubiquitin-dependent protein catabolic process; negative regulation of cell proliferation; induction of apoptosis by intracellular signals; viral reproduction; cytosolic calcium ion homeostasis; calcium ion transmembrane transport; G1/S transition of mitotic cell cycle | |
| CUL7 | ubiquitin-dependent protein catabolic process; interspecies interaction between organisms; endoplasmic reticulum unfolded protein response; activation of signaling protein activity involved in unfolded protein response; vasculogenesis; proteolysis | |
| CUL9 | ubiquitin-dependent protein catabolic process | |
| CUTC | copper ion transport; copper ion homeostasis; protein tetramerization | |
| CUX1 | auditory receptor cell differentiation; negative regulation of transcription from RNA polymerase II promoter; retrograde transport, vesicle recycling within Golgi; regulation of transcription from RNA polymerase II promoter; transport; intra-Golgi vesicle-mediated transport; multicellular organismal development; lung development | |
| CUX2 | negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| CUZD1 | substrate-dependent cell migration, cell attachment to substrate; cell cycle; cell adhesion; hormone-mediated signaling pathway; cell proliferation; trypsinogen activation; cell division | |
| CWC27 | nuclear mRNA splicing, via spliceosome; protein folding | |
| CWH43 | GPI anchor biosynthetic process | |
| CXCL8 | negative regulation of cell proliferation; calcium-mediated signaling; regulation of cell adhesion; neutrophil chemotaxis; endoplasmic reticulum unfolded protein response; receptor internalization; intracellular signal transduction; neutrophil activation; cellular response to fibroblast growth factor stimulus; regulation of retroviral genome replication; negative regulation of G-protein coupled receptor protein signaling pathway; embryonic digestive tract development; induction of positive chemotaxis; cellular response to lipopolysaccharide; cellular response to interleukin-1; cellular response to tumor necrosis factor; positive regulation of neutrophil chemotaxis; G-protein coupled receptor signaling pathway; signal transduction; cell cycle arrest; activation of signaling protein activity involved in unfolded protein response; immune response; inflammatory response; chemotaxis; cellular component movement; response to molecule of bacterial origin; angiogenesis | |
| CXCR4 | regulation of chemotaxis; myelin maintenance; activation of MAPK activity; response to hypoxia; dendritic cell chemotaxis; apoptotic process; inflammatory response; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; response to virus; viral reproduction; interspecies interaction between organisms; initiation of viral infection; calcium-mediated signaling; entry into host cell; positive regulation of oligodendrocyte differentiation | |
| CXCR6 | viral genome replication; G-protein coupled receptor signaling pathway | |
| CXorf21 | - | |
| CXorf22 | - | |
| CXorf23 | - | |
| CXorf36 | - | |
| CXorf57 | - | |
| CXorf65 | - | |
| CXXC1 | endoplasmic reticulum unfolded protein response; positive regulation of transcription, DNA-dependent; histone H3-K4 methylation; activation of signaling protein activity involved in unfolded protein response; regulation of transcription, DNA-dependent | |
| CYB561A3 | - | |
| CYB561D1 | transport; electron transport chain | |
| CYB561D2 | electron transport chain; transport | |
| CYB5D1 | - | |
| CYB5R1 | sterol biosynthetic process | |
| CYB5R4 | generation of precursor metabolites and energy; oxidation-reduction process; cell development; response to antibiotic; glucose homeostasis; insulin secretion; superoxide metabolic process; detection of oxygen | |
| CYC1 | transport; respiratory electron transport chain; response to glucagon stimulus; small molecule metabolic process | |
| CYFIP1 | cell differentiation; ruffle organization; regulation of cell shape; axon extension; nervous system development; multicellular organismal development; lamellipodium assembly | |
| CYHR1 | - | |
| CYLC1 | multicellular organismal development; spermatogenesis; cell differentiation | |
| CYLC2 | multicellular organismal development; spermatogenesis; cell differentiation | |
| CYLD | positive regulation of extrinsic apoptotic signaling pathway; protein K63-linked deubiquitination; translation; proteolysis; ubiquitin-dependent protein catabolic process; induction of apoptosis; cell cycle; regulation of mitotic cell cycle; Wnt receptor signaling pathway; negative regulation of type I interferon production; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; negative regulation of NF-kappaB import into nucleus; innate immune response; nucleotide-binding oligomerization domain containing signaling pathway; regulation of microtubule cytoskeleton organization; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of NF-kappaB transcription factor activity | |
| CYP11A1 | response to L-ascorbic acid; response to insecticide; Leydig cell differentiation; response to vitamin E; hippocampus development; cerebellum development; phthalate metabolic process; phenol-containing compound metabolic process; dibenzo-p-dioxin metabolic process; biphenyl metabolic process; response to acid; organic acid metabolic process; C21-steroid hormone biosynthetic process; progesterone biosynthetic process; estrogen biosynthetic process; xenobiotic metabolic process; response to nutrient; mating behavior; steroid metabolic process; cholesterol metabolic process; response to salt stress; response to gamma radiation; Schwann cell differentiation; vitamin D metabolic process; response to genistein; cellular response to transforming growth factor beta stimulus; cellular response to peptide hormone stimulus; cellular response to follicle-stimulating hormone stimulus; cellular response to tumor necrosis factor; cellular response to interleukin-1; cellular response to cAMP; cellular response to cadmium ion | |
| CYP1A1 | insecticide metabolic process; drug metabolic process; dibenzo-p-dioxin catabolic process; response to food; response to lipopolysaccharide; developmental process; response to vitamin A; small molecule metabolic process; vitamin D metabolic process; response to drug; 9-cis-retinoic acid biosynthetic process; camera-type eye development; cellular lipid metabolic process; oxidation-reduction process; response to organic cyclic compound; response to iron(III) ion; flavonoid metabolic process; coumarin metabolic process; embryo development ending in birth or egg hatching; response to herbicide; response to nematode; response to virus; response to wounding; amine metabolic process; cell proliferation; xenobiotic metabolic process; porphyrin-containing compound metabolic process; response to hypoxia; response to antibiotic; response to arsenic-containing substance; digestive tract development; hydrogen peroxide biosynthetic process; response to hyperoxia; maternal process involved in parturition; hepatocyte differe | |
| CYP1A2 | methylation; hydrogen peroxide biosynthetic process; monocarboxylic acid metabolic process; drug catabolic process; exogenous drug catabolic process; small molecule metabolic process; cellular respiration; heterocycle metabolic process; oxidation-reduction process; oxidative demethylation; oxidative deethylation; lung development; dibenzo-p-dioxin metabolic process; drug metabolic process; monoterpenoid metabolic process; regulation of gene expression; alkaloid metabolic process; post-embryonic development; toxin biosynthetic process; xenobiotic metabolic process; porphyrin-containing compound metabolic process; cellular aromatic compound metabolic process; steroid catabolic process | |
| CYP1B1 | retina vasculature development in camera-type eye; oxidation-reduction process; small molecule metabolic process; endothelial cell migration; response to organic substance; response to toxin; toxin metabolic process; estrogen metabolic process; visual perception; xenobiotic metabolic process; endothelial cell-cell adhesion; cellular aromatic compound metabolic process; angiogenesis | |
| CYP20A1 | - | |
| CYP24A1 | oxidation-reduction process; osteoblast differentiation; vitamin metabolic process; xenobiotic metabolic process; steroid metabolic process; vitamin D receptor signaling pathway; response to vitamin D; small molecule metabolic process; vitamin D catabolic process; vitamin D metabolic process | |
| CYP26A1 | vitamin metabolic process; xenobiotic metabolic process; metabolic process; retinoic acid catabolic process; small molecule metabolic process; negative regulation of retinoic acid receptor signaling pathway | |
| CYP26C1 | oxidation-reduction process; vitamin metabolic process; negative regulation of retinoic acid receptor signaling pathway; xenobiotic metabolic process; organelle fusion; central nervous system development; anterior/posterior pattern specification; small molecule metabolic process; retinoic acid catabolic process; neural crest cell development | |
| CYP27A1 | small molecule metabolic process; bile acid metabolic process; cholesterol metabolic process; xenobiotic metabolic process; bile acid biosynthetic process | |
| CYP27B1 | vitamin D biosynthetic process; vitamin D catabolic process; decidualization; response to estrogen stimulus; positive regulation of keratinocyte differentiation; small molecule metabolic process; response to tumor necrosis factor; vitamin D metabolic process; calcium ion homeostasis; G1 to G0 transition; positive regulation of vitamin D receptor signaling pathway; vitamin metabolic process; xenobiotic metabolic process; calcium ion transport; steroid metabolic process; negative regulation of cell proliferation; positive regulation of vitamin D 24-hydroxylase activity; response to interferon-gamma; negative regulation of calcidiol 1-monooxygenase activity; response to vitamin D; response to lipopolysaccharide; negative regulation of cell growth; bone mineralization; regulation of bone mineralization | |
| CYP2C18 | xenobiotic metabolic process; small molecule metabolic process | |
| CYP2C9 | oxidative demethylation; oxidation-reduction process; small molecule metabolic process; cellular amide metabolic process; exogenous drug catabolic process; monocarboxylic acid metabolic process; urea metabolic process; drug metabolic process; monoterpenoid metabolic process; steroid metabolic process; drug catabolic process; xenobiotic metabolic process | |
| CYP2J2 | epoxygenase P450 pathway; small molecule metabolic process; linoleic acid metabolic process; regulation of heart contraction; xenobiotic metabolic process; icosanoid metabolic process | |
| CYP2R1 | small molecule metabolic process; vitamin D metabolic process; response to ionizing radiation; response to cesium ion; steroid metabolic process; vitamin metabolic process; xenobiotic metabolic process | |
| CYP2U1 | xenobiotic metabolic process; small molecule metabolic process | |
| CYP2W1 | xenobiotic metabolic process; small molecule metabolic process | |
| CYP39A1 | bile acid catabolic process; bile acid metabolic process; digestion; xenobiotic metabolic process; cholesterol catabolic process; bile acid biosynthetic process; small molecule metabolic process | |
| CYP3A5 | small molecule metabolic process; drug catabolic process; alkaloid catabolic process; steroid metabolic process; xenobiotic metabolic process; oxidative demethylation | |
| CYP46A1 | xenobiotic metabolic process; nervous system development; cholesterol catabolic process; bile acid biosynthetic process; bile acid metabolic process; small molecule metabolic process | |
| CYP4B1 | xenobiotic metabolic process; small molecule metabolic process | |
| CYP4F11 | small molecule metabolic process; xenobiotic metabolic process; inflammatory response; oxidation-reduction process | |
| CYP4F22 | - | |
| CYP4V2 | response to stimulus; fatty acid omega-oxidation; visual perception | |
| CYP7B1 | prostate gland epithelium morphogenesis; small molecule metabolic process; bile acid biosynthetic process; xenobiotic metabolic process; memory; circadian rhythm; cholesterol metabolic process; bile acid metabolic process; positive regulation of epithelial cell proliferation; response to drug; cell death; negative regulation of intracellular estrogen receptor signaling pathway; response to cAMP | |
| CYP8B1 | small molecule metabolic process; bile acid metabolic process; xenobiotic metabolic process; bile acid biosynthetic process | |
| CYR61 | positive regulation of cell-substrate adhesion; positive regulation of cell migration; extracellular matrix organization; positive regulation of phospholipase activity; anatomical structure morphogenesis; cell proliferation; chemotaxis; ventricular septum development; positive regulation of ceramide biosynthetic process; reactive oxygen species metabolic process; regulation of ERK1 and ERK2 cascade; positive regulation of cartilage development; labyrinthine layer blood vessel development; chorio-allantoic fusion; chondroblast differentiation; atrial septum morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of cell growth; intussusceptive angiogenesis; atrioventricular valve morphogenesis; apoptosis involved in heart morphogenesis; negative regulation of apoptotic process; positive regulation of apoptotic process; positive regulation of osteoblast proliferation; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regul | |
| CYTH1 | regulation of ARF protein signal transduction; vesicle-mediated transport; regulation of cell adhesion | |
| CYTH2 | regulation of ARF protein signal transduction; endocytosis; regulation of cell adhesion; actin cytoskeleton organization | |
| CYTH4 | regulation of ARF protein signal transduction; regulation of cell adhesion | |
| CYTIP | regulation of cell adhesion | |
| CYYR1 | - | |
| D2HGDH | response to cobalt ion; 2-oxoglutarate metabolic process; response to manganese ion; response to calcium ion; response to zinc ion; small molecule metabolic process; cellular protein metabolic process; response to magnesium ion | |
| DAB1 | multicellular organismal development; nervous system development; cell differentiation | |
| DAB2 | pinocytosis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; negative regulation of canonical Wnt receptor signaling pathway; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; negative regulation of cell growth; cell proliferation; cell morphogenesis involved in differentiation; excretion; in utero embryonic development; receptor-mediated endocytosis; negative regulation of protein binding; positive regulation of protein phosphorylation | |
| DAB2IP | negative regulation of Ras protein signal transduction; negative regulation of fibroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of epithelial cell proliferation; regulation of small GTPase mediated signal transduction; apoptosis in response to endoplasmic reticulum stress; negative regulation of catenin import into nucleus; cellular response to tumor necrosis factor; positive regulation of JUN kinase activity; negative regulation of MAP kinase activity; negative regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; activation of JUN kinase activity; positive regulation of signal transduction; negative regulation of epithelial cell migration; negative regulation of epithelial to mesenchymal transition; negative regulation of NF-kappaB transcription factor activity; | |
| DACH1 | negative regulation of cell migration; negative regulation of transcription by competitive promoter binding; multicellular organismal development; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| DACH2 | development of primary female sexual characteristics; multicellular organismal development; regulation of transcription, DNA-dependent | |
| DACT1 | multicellular organismal development; Wnt receptor signaling pathway | |
| DAG1 | negative regulation of protein kinase B signaling cascade; interspecies interaction between organisms; negative regulation of MAPK cascade; microtubule anchoring; negative regulation of cell migration; virus-host interaction; cytoskeletal anchoring at plasma membrane; NLS-bearing substrate import into nucleus; membrane protein ectodomain proteolysis | |
| DAGLA | platelet activation; lipid catabolic process; cell death; blood coagulation | |
| DAGLB | blood coagulation; lipid catabolic process; platelet activation | |
| DALRD3 | arginyl-tRNA aminoacylation | |
| DAO | small molecule metabolic process; D-alanine catabolic process; proline catabolic process; cellular nitrogen compound metabolic process; D-serine catabolic process; glyoxylate metabolic process | |
| DAPK1 | induction of apoptosis; apoptotic process; protein phosphorylation; regulation of N-methyl-D-aspartate selective glutamate receptor activity; protein autophosphorylation; regulation of apoptotic process; regulation of autophagy; induction of apoptosis by extracellular signals; intracellular protein kinase cascade; signal transduction; anti-apoptosis | |
| DAPK2 | anoikis; protein autophosphorylation; regulation of apoptotic process; induction of apoptosis; protein phosphorylation; regulation of autophagy; intracellular protein kinase cascade | |
| DAPK3 | regulation of smooth muscle contraction; regulation of actin cytoskeleton reorganization; regulation of cell motility; positive regulation of canonical Wnt receptor signaling pathway; protein autophosphorylation; regulation of apoptotic process; neuron differentiation; chromatin modification; regulation of autophagy; intracellular protein kinase cascade; regulation of mitosis; induction of apoptosis; protein phosphorylation; regulation of transcription, DNA-dependent; cytokinesis | |
| DARS | translation; gene expression; protein complex assembly; tRNA aminoacylation for protein translation; aspartyl-tRNA aminoacylation | |
| DARS2 | mitochondrial asparaginyl-tRNA aminoacylation; tRNA aminoacylation; gene expression; tRNA aminoacylation for protein translation | |
| DAW1 | - | |
| DAZAP1 | multicellular organismal development; spermatogenesis; cell differentiation | |
| DBH | sensory perception of taste; small molecule metabolic process; cellular response to nicotine; cellular response to manganese ion; bone development; leukocyte migration; response to pain; behavioral response to ethanol; response to copper ion; octopamine metabolic process; positive regulation of vasoconstriction; cytokine production; response to peptide hormone stimulus; regulation of apoptotic process; maternal behavior; fear response; glucose homeostasis; catecholamine biosynthetic process; norepinephrine biosynthetic process; dopamine catabolic process; blood vessel remodeling; visual learning; response to iron ion; response to ozone; multicellular organismal aging; response to organic cyclic compound; response to estradiol stimulus; cellular nitrogen compound metabolic process; social behavior; regulation of cell proliferation; homoiothermy; locomotory behavior; response to amphetamine; memory; synaptic transmission; leukocyte mediated immunity | |
| DBN1 | actin filament organization; multicellular organismal development; nervous system development; cell differentiation; regulation of neuronal synaptic plasticity; regulation of dendrite development | |
| DBNL | endocytosis; apoptotic process; cellular component disassembly involved in apoptosis; activation of JUN kinase activity; Rac protein signal transduction | |
| DBR1 | RNA splicing, via transesterification reactions; nuclear mRNA splicing, via spliceosome | |
| DBX2 | - | |
| DCAF11 | protein ubiquitination | |
| DCAF12L2 | - | |
| DCAF15 | - | |
| DCAF16 | protein ubiquitination | |
| DCAF4L2 | - | |
| DCAF5 | protein ubiquitination | |
| DCAF8 | protein ubiquitination | |
| DCAKD | coenzyme A biosynthetic process | |
| DCC | response to amphetamine; negative regulation of dendrite development; positive regulation of ERK1 and ERK2 cascade; negative regulation of collateral sprouting; regulation of apoptotic process; negative regulation of neuron projection development; positive regulation of neuron projection development; axon guidance; axonogenesis; multicellular organismal development; induction of apoptosis; apoptotic process | |
| DCDC1 | intracellular signal transduction | |
| DCDC2 | neuron migration; nervous system development; cellular defense response; intracellular signal transduction | |
| DCHS2 | cell adhesion; homophilic cell adhesion | |
| DCLK1 | intracellular signal transduction; central nervous system development; protein phosphorylation; multicellular organismal development; nervous system development; response to virus; endosome transport; cell differentiation | |
| DCLK2 | intracellular signal transduction | |
| DCLK3 | - | |
| DCLRE1A | cell cycle; DNA repair; mitosis; cell division | |
| DCLRE1B | telomere maintenance; cell cycle checkpoint; DNA repair; telomeric loop formation; protection from non-homologous end joining at telomere; telomeric 3' overhang formation | |
| DCN | kidney development; placenta development; skeletal muscle tissue development; aging; response to mechanical stimulus; organ morphogenesis; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; response to lipopolysaccharide; wound healing | |
| DCPS | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; RNA metabolic process; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; deadenylation-dependent decapping of nuclear-transcribed mRNA; gene expression; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | |
| DCST1 | - | |
| DCST2 | - | |
| DCSTAMP | osteoclast differentiation | |
| DCT | cell development; developmental pigmentation; ventricular zone neuroblast division; epidermis development; melanin biosynthetic process from tyrosine; positive regulation of neuroblast proliferation | |
| DCTN1 | G2/M transition of mitotic cell cycle; endoplasmic reticulum unfolded protein response; cell death; nervous system development; mitosis; transport; mitotic cell cycle; activation of signaling protein activity involved in unfolded protein response | |
| DCTN4 | - | |
| DCUN1D2 | - | |
| DCX | central nervous system development; response to electrical stimulus; dendrite morphogenesis; axon extension; intracellular signal transduction; cell differentiation; central nervous system projection neuron axonogenesis; brain development; axon guidance; nervous system development; multicellular organismal development; neuron migration | |
| DCXR | NADP metabolic process; D-xylose metabolic process; carbohydrate metabolic process; xylulose metabolic process; glucose metabolic process; protein homotetramerization; oxidation-reduction process | |
| DDB1 | cell cycle checkpoint; interspecies interaction between organisms; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; Wnt receptor signaling pathway; nucleotide-excision repair; DNA repair; nucleotide-excision repair, DNA damage removal | |
| DDHD1 | lipid catabolic process | |
| DDHD2 | lipid catabolic process | |
| DDI1 | proteolysis | |
| DDIAS | cell cycle arrest; cell cycle; apoptotic process | |
| DDIT4L | negative regulation of signal transduction | |
| DDO | hormone metabolic process; insemination; grooming behavior; aspartate catabolic process; aspartate metabolic process | |
| DDOST | response to cytokine stimulus; translation; protein glycosylation; protein N-linked glycosylation; SRP-dependent cotranslational protein targeting to membrane; gene expression; protein N-linked glycosylation via asparagine; innate immune response; cellular protein metabolic process; post-translational protein modification; T cell activation | |
| DDR2 | chondrocyte proliferation; positive regulation of extracellular matrix disassembly; positive regulation of sequence-specific DNA binding transcription factor activity; protein autophosphorylation; positive regulation of protein kinase activity; positive regulation of osteoblast differentiation; collagen-activated tyrosine kinase receptor signaling pathway; regulation of bone mineralization; peptidyl-tyrosine phosphorylation; positive regulation of fibroblast migration; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; positive regulation of fibroblast proliferation; cell adhesion; endochondral bone growth; ossification; regulation of extracellular matrix disassembly | |
| DDX1 | regulation of translational initiation; nucleic acid phosphodiester bond hydrolysis; DNA duplex unwinding; multicellular organismal development; mRNA processing; regulation of transcription, DNA-dependent; double-strand break repair; spliceosome assembly | |
| DDX17 | RNA processing; positive regulation of transcription from RNA polymerase II promoter; regulation of skeletal muscle cell differentiation; positive regulation of intracellular estrogen receptor signaling pathway | |
| DDX18 | - | |
| DDX20 | RNA processing; positive regulation of apoptotic process; ncRNA metabolic process; RNA metabolic process; gene expression; RNA splicing; induction of apoptosis; mRNA processing; negative regulation of transcription from RNA polymerase II promoter; spliceosomal snRNP assembly; assembly of spliceosomal tri-snRNP | |
| DDX24 | RNA metabolic process | |
| DDX26B | - | |
| DDX28 | - | |
| DDX39A | nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; RNA splicing | |
| DDX3X | interspecies interaction between organisms | |
| DDX3Y | - | |
| DDX4 | sperm motility; multicellular organismal development | |
| DDX41 | nuclear mRNA splicing, via spliceosome; RNA processing; apoptotic process; multicellular organismal development; RNA splicing | |
| DDX42 | regulation of anti-apoptosis; protein localization | |
| DDX43 | - | |
| DDX46 | RNA splicing; mRNA processing | |
| DDX47 | rRNA processing; mRNA processing; apoptotic process; RNA splicing | |
| DDX49 | - | |
| DDX51 | rRNA processing | |
| DDX53 | - | |
| DDX55 | - | |
| DDX56 | rRNA processing | |
| DDX58 | innate immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of interferon-beta production; positive regulation of interferon-alpha production; negative regulation of type I interferon production; detection of virus; positive regulation of defense response to virus by host; positive regulation of transcription factor import into nucleus | |
| DDX59 | - | |
| DDX60 | response to virus | |
| DEAF1 | regulation of mammary gland epithelial cell proliferation; germ cell development; embryonic skeletal system development; nervous system development; neural tube closure; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; anatomical structure morphogenesis; multicellular organismal development | |
| DECR1 | fatty acid beta-oxidation; cellular lipid metabolic process; small molecule metabolic process; protein homotetramerization | |
| DEDD | induction of apoptosis; spermatogenesis; induction of apoptosis via death domain receptors; negative regulation of transcription, DNA-dependent; regulation of apoptotic process | |
| DEF6 | - | |
| DEFA4 | killing of cells of other organism; defense response to bacterium; innate immune response; defense response to fungus | |
| DEFB112 | defense response to bacterium | |
| DEFB115 | defense response to bacterium | |
| DEFB116 | defense response to bacterium | |
| DEFB125 | defense response to bacterium | |
| DEFB126 | defense response to bacterium | |
| DEFB128 | defense response to bacterium | |
| DEFB129 | defense response to bacterium | |
| DEGS1 | sphingolipid biosynthetic process; unsaturated fatty acid biosynthetic process; sphingolipid metabolic process; small molecule metabolic process | |
| DEK | viral genome replication; chromatin modification; signal transduction; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter | |
| DENND1A | synaptic vesicle endocytosis | |
| DENND1B | - | |
| DENND2A | - | |
| DENND2C | - | |
| DENND2D | - | |
| DENND3 | - | |
| DENND4C | - | |
| DENND5A | - | |
| DENND6A | - | |
| DEPDC1B | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction | |
| DEPDC4 | intracellular signal transduction | |
| DEPDC5 | intracellular signal transduction | |
| DEPDC7 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction | |
| DEPTOR | negative regulation of protein kinase activity; negative regulation of TOR signaling cascade; intracellular signal transduction; regulation of apoptotic process; negative regulation of cell size | |
| DERL3 | ER-associated protein catabolic process; endoplasmic reticulum unfolded protein response | |
| DES | regulation of heart contraction; muscle filament sliding; muscle contraction; cytoskeleton organization | |
| DESI2 | - | |
| DFNB31 | sensory perception of sound; retina homeostasis; sensory perception of light stimulus; inner ear receptor stereocilium organization | |
| DFNB59 | sensory perception of sound | |
| DGAT1 | small molecule metabolic process; long-chain fatty-acyl-CoA metabolic process; triglyceride biosynthetic process; triglyceride metabolic process; lipid storage; insulin secretion; cellular lipid metabolic process; very-low-density lipoprotein particle assembly; diacylglycerol metabolic process; glycerolipid metabolic process | |
| DGAT2 | glycerol metabolic process; lipid biosynthetic process; triglyceride biosynthetic process; lipid storage; low-density lipoprotein particle clearance; long-chain fatty-acyl-CoA metabolic process; cellular triglyceride homeostasis; cholesterol homeostasis; cellular lipid metabolic process; small molecule metabolic process; diacylglycerol metabolic process; fatty acid homeostasis; fat pad development; cellular response to oleic acid; regulation of plasma lipoprotein particle levels | |
| DGCR2 | organ morphogenesis; cell adhesion | |
| DGCR8 | primary miRNA processing | |
| DGKA | platelet activation; intracellular signal transduction; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation | |
| DGKD | response to organic substance; endocytosis; signal transduction; epidermal growth factor receptor signaling pathway; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; multicellular organismal development; blood coagulation; protein transport; cell growth; second-messenger-mediated signaling; platelet activation; diacylglycerol metabolic process; protein homooligomerization | |
| DGKE | phospholipid biosynthetic process; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation; intracellular signal transduction; platelet activation | |
| DGKG | intracellular signal transduction; signal transduction; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation; platelet activation; neuron development | |
| DGKH | activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation; platelet activation; intracellular signal transduction; protein oligomerization | |
| DGKI | positive regulation of Ras protein signal transduction; negative regulation of catalytic activity; intracellular signal transduction; regulation of Rap GTPase activity; platelet activation; blood coagulation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway | |
| DGKQ | activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; G-protein coupled receptor signaling pathway; protein kinase C signaling cascade; thrombin receptor signaling pathway; intracellular signal transduction; response to ATP; platelet activation; cAMP-mediated signaling; blood coagulation | |
| DGKZ | lipid phosphorylation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation; cell migration; platelet activation; mitotic cell cycle G1/S transition DNA damage checkpoint; intracellular signal transduction; negative regulation of mitotic cell cycle; negative regulation of Ras protein signal transduction | |
| DHCR7 | cell differentiation; blood vessel development; cholesterol biosynthetic process; post-embryonic development; lung development; multicellular organism growth; regulation of cell proliferation; small molecule metabolic process; regulation of cholesterol biosynthetic process | |
| DHDH | D-xylose catabolic process; carbohydrate metabolic process | |
| DHODH | 'de novo' pyrimidine base biosynthetic process; pyrimidine nucleotide biosynthetic process; UMP biosynthetic process; positive regulation of apoptotic process; small molecule metabolic process; pyrimidine nucleoside biosynthetic process; nucleobase-containing small molecule metabolic process; regulation of mitochondrial fission; pyrimidine base metabolic process | |
| DHRS1 | - | |
| DHRS13 | - | |
| DHRS2 | oxidation-reduction process; negative regulation of cell proliferation; response to toxin; negative regulation of apoptotic process; cellular response to oxidative stress; myeloid dendritic cell differentiation; C21-steroid hormone metabolic process | |
| DHRS3 | retinol metabolic process; visual perception | |
| DHRS7 | - | |
| DHRS7B | - | |
| DHTKD1 | tricarboxylic acid cycle; glycolysis | |
| DHX15 | mRNA processing; RNA splicing | |
| DHX30 | - | |
| DHX32 | - | |
| DHX33 | positive regulation of transcription from RNA polymerase I promoter | |
| DHX36 | - | |
| DHX37 | - | |
| DHX38 | RNA splicing; mRNA 3'-end processing; mRNA export from nucleus; gene expression; nuclear mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter | |
| DHX40 | - | |
| DHX57 | - | |
| DHX58 | innate immune response | |
| DHX8 | nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing | |
| DHX9 | gene expression; CRD-mediated mRNA stabilization; cellular response to heat; RNA splicing; nuclear mRNA splicing, via spliceosome | |
| DIAPH1 | cellular component organization; sensory perception of sound; cytoskeleton organization; cellular response to histamine; regulation of release of sequestered calcium ion into cytosol; protein localization to microtubule; regulation of microtubule-based process; neuron projection development; actin filament polymerization; actin cytoskeleton organization; regulation of cell shape | |
| DIAPH2 | cytokinesis; multicellular organismal development; female gamete generation; cellular component organization; actin cytoskeleton organization; actin filament polymerization; cell differentiation; oogenesis | |
| DIAPH3 | cellular component organization; actin cytoskeleton organization | |
| DICER1 | defense response to virus; spindle assembly; cardiac muscle cell development; intestinal epithelial cell development; regulation of enamel mineralization; branching morphogenesis of a tube; nerve development; spleen development; positive regulation of transcription from RNA polymerase II promoter; regulation of neuron differentiation; digestive tract development; neuron projection morphogenesis; regulation of cell differentiation; negative regulation of transcription from RNA polymerase II promoter; regulation of viral genome replication; negative regulation of apoptotic process; regulation of odontogenesis of dentin-containing tooth; cerebral cortex development; positive regulation of gene expression; gene silencing by RNA; multicellular organism growth; negative regulation of Schwann cell proliferation; targeting of mRNA for destruction involved in RNA interference; production of siRNA involved in RNA interference; zygote asymmetric cell division; lung development; positive regulation of Schwann cell differ | |
| DIDO1 | transcription, DNA-dependent; apoptotic process | |
| DIO1 | thyroid hormone generation; hormone biosynthetic process; small molecule metabolic process; cellular nitrogen compound metabolic process | |
| DIP2B | - | |
| DIP2C | - | |
| DIRAS1 | signal transduction; small GTPase mediated signal transduction | |
| DIRAS3 | regulation of cyclin-dependent protein kinase activity; GTP catabolic process; regulation of gene expression by genetic imprinting; signal transduction; small GTPase mediated signal transduction | |
| DIS3 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; rRNA processing; gene expression; RNA metabolic process; mRNA metabolic process; CUT catabolic process; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; rRNA catabolic process | |
| DIS3L | rRNA catabolic process | |
| DIS3L2 | - | |
| DISC1 | microtubule cytoskeleton organization; positive regulation of neuroblast proliferation; multicellular organismal development; neuron migration; nervous system development; positive regulation of Wnt receptor signaling pathway | |
| DISP1 | dorsal/ventral pattern formation; embryonic pattern specification; peptide transport; determination of left/right symmetry; regulation of protein secretion; diaphragm development; protein homotrimerization; smoothened signaling pathway; patched ligand maturation | |
| DISP2 | smoothened signaling pathway | |
| DKK2 | multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway; positive regulation of canonical Wnt receptor signaling pathway | |
| DKK3 | adrenal gland development; negative regulation of aldosterone biosynthetic process; negative regulation of transcription, DNA-dependent; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of cortisol biosynthetic process; anatomical structure morphogenesis; multicellular organismal development | |
| DKKL1 | signal transduction; anatomical structure morphogenesis; positive regulation of fat cell differentiation | |
| DLC1 | actin cytoskeleton organization; negative regulation of cell migration; hindbrain morphogenesis; regulation of cell shape; negative regulation of cell proliferation; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; negative regulation of stress fiber assembly; activation of phospholipase C activity; signal transduction; negative regulation of Rho protein signal transduction; neural tube closure; regulation of actin cytoskeleton organization; cellular response to insulin stimulus; small GTPase mediated signal transduction; positive regulation of Rho GTPase activity; heart morphogenesis; forebrain development; regulation of small GTPase mediated signal transduction; focal adhesion assembly; positive regulation of protein dephosphorylation | |
| DLD | small molecule metabolic process; cell redox homeostasis; sperm capacitation; dihydrolipoamide metabolic process; regulation of membrane potential; cellular nitrogen compound metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; lipoate metabolic process; branched chain family amino acid catabolic process; gastrulation; lysine catabolic process; proteolysis; mitochondrial electron transport, NADH to ubiquinone; 2-oxoglutarate metabolic process; pyruvate metabolic process; tricarboxylic acid cycle; aging | |
| DLEC1 | negative regulation of cell proliferation | |
| DLG1 | mitotic cell cycle G1/S transition checkpoint; tight junction assembly; cortical actin cytoskeleton organization; cell-cell adhesion; axon guidance; synaptic transmission; establishment or maintenance of cell polarity; actin filament organization; endothelial cell proliferation; interspecies interaction between organisms; negative regulation of mitotic cell cycle; protein localization in plasma membrane | |
| DLG2 | synaptic transmission; negative regulation of phosphatase activity; sensory perception of pain; receptor clustering; neuronal ion channel clustering | |
| DLG3 | synaptic transmission; axon guidance; negative regulation of cell proliferation; negative regulation of phosphatase activity | |
| DLG5 | regulation of apoptotic process; intracellular signal transduction; cell-cell adhesion; negative regulation of cell proliferation; signal transduction | |
| DLGAP1 | synaptic transmission | |
| DLGAP3 | cell-cell signaling | |
| DLGAP4 | cell-cell signaling | |
| DLGAP5 | mitotic chromosome movement towards spindle pole; M phase of mitotic cell cycle; cell cycle; positive regulation of mitotic metaphase/anaphase transition; cell proliferation; cell-cell signaling | |
| DLK1 | multicellular organismal development; embryo development; post-embryonic development; embryonic skeletal system development | |
| DLK2 | regulation of fat cell differentiation | |
| DLL1 | negative regulation of neuron differentiation; negative regulation of myeloid cell differentiation; somite specification; cell-cell signaling; inner ear development; regulation of neurogenesis; proximal tubule development; multicellular organismal development; loop of Henle development; neuronal stem cell maintenance; Notch receptor processing; cell fate determination; negative regulation of auditory receptor cell differentiation; determination of left/right symmetry; compartment pattern specification; hemopoiesis; cell differentiation; regulation of cell adhesion; Notch signaling pathway | |
| DLL3 | somitogenesis; negative regulation of astrocyte differentiation; paraxial mesoderm development; skeletal system development; negative regulation of Notch signaling pathway; positive regulation of neurogenesis; negative regulation of neurogenesis; cell differentiation; multicellular organismal development; compartment pattern specification; central nervous system development; tissue development | |
| DLST | cellular nitrogen compound metabolic process; generation of precursor metabolites and energy; tricarboxylic acid cycle; 2-oxoglutarate metabolic process; lysine catabolic process; NADH metabolic process; metabolic process; small molecule metabolic process | |
| DLX1 | cell differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of oligodendrocyte differentiation; embryonic skeletal system development; negative regulation of neuron apoptosis; odontogenesis of dentin-containing tooth; cerebral cortex GABAergic interneuron fate commitment; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; forebrain neuron differentiation; hippocampus development; proximal/distal pattern formation; multicellular organismal development | |
| DLX3 | blood vessel development; placenta development; regulation of transcription, DNA-dependent; multicellular organismal development | |
| DLX5 | cell proliferation; axon guidance; nervous system development; multicellular organismal development; endochondral ossification; osteoblast differentiation; skeletal system development; epithelial cell differentiation; palate development; embryonic limb morphogenesis; specification of segmental identity, mandibular segment; inner ear morphogenesis; ear development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of osteoblast differentiation; anatomical structure formation involved in morphogenesis; positive regulation of epithelial cell proliferation; positive regulation of canonical Wnt receptor signaling pathway; bone morphogenesis; face morphogenesis; head development; olfactory pit development | |
| DMAP1 | chromatin modification; histone H4 acetylation; histone H2A acetylation; regulation of growth; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor import into nucleus; negative regulation of transcription, DNA-dependent | |
| DMC1 | pachytene; ovarian follicle development; female gamete generation; cell cycle; oocyte maturation; DNA metabolic process; spermatid development; male meiosis I; spermatogenesis; reciprocal meiotic recombination; meiosis | |
| DMD | neuron projection morphogenesis; muscle organ development; skeletal muscle tissue development; olfactory nerve structural organization; muscle filament sliding; peptide biosynthetic process; neurotransmitter receptor metabolic process; muscle cell homeostasis; regulation of transcription, DNA-dependent | |
| DMGDH | choline metabolic process; glycine catabolic process; glycine metabolic process | |
| DMKN | - | |
| DMPK | muscle cell apoptosis; regulation of sodium ion transport; protein phosphorylation; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction; regulation of myotube differentiation; regulation of heart contraction; nuclear envelope organization; cellular calcium ion homeostasis | |
| DMRT1 | intracellular signal transduction; male gonad development; sex differentiation; sex determination; multicellular organismal development; cell differentiation; regulation of transcription, DNA-dependent | |
| DMRT3 | multicellular organismal development; sex differentiation; cell differentiation; regulation of transcription, DNA-dependent | |
| DMRTA1 | cell differentiation; sex differentiation; regulation of transcription, DNA-dependent | |
| DMTF1 | cell cycle; regulation of transcription, DNA-dependent | |
| DMWD | meiosis | |
| DMXL1 | - | |
| DMXL2 | - | |
| DNAAF1 | axonemal dynein complex assembly; cilium morphogenesis | |
| DNAH14 | microtubule-based movement | |
| DNAH2 | microtubule-based movement; ciliary or flagellar motility | |
| DNAH3 | microtubule-based movement; ciliary or flagellar motility | |
| DNAH5 | microtubule-based movement; ciliary or flagellar motility; metabolic process | |
| DNAH6 | microtubule-based movement | |
| DNAH7 | microtubule-based movement; ciliary or flagellar motility | |
| DNAH8 | microtubule-based movement; ciliary or flagellar motility | |
| DNAH9 | spermatogenesis; cell projection organization; cellular component movement; microtubule-based movement | |
| DNAI2 | cilium assembly; cell projection organization | |
| DNAJA3 | apoptotic process; negative regulation of protein kinase activity; embryo development; protein folding; mitochondrial DNA replication; negative regulation of transcription from RNA polymerase II promoter; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic process; positive regulation of T cell proliferation; response to interferon-gamma; T cell differentiation in thymus; cell death; positive regulation of protein ubiquitination; negative regulation of NF-kappaB transcription factor activity; skeletal muscle acetylcholine-gated channel clustering; regulation of catalytic activity; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptotic process; activation-induced cell death of T cells; protein stabilization; response to heat; negative regulation of interferon-gamma-mediated signaling pathway; negative regulation of cell pro | |
| DNAJA4 | response to heat; protein folding | |
| DNAJB11 | protein folding; activation of signaling protein activity involved in unfolded protein response; mRNA modification; endoplasmic reticulum unfolded protein response | |
| DNAJB12 | protein folding | |
| DNAJB2 | positive regulation of protein ubiquitination; negative regulation of protein deubiquitination; negative regulation of inclusion body assembly; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ER-associated protein catabolic process; negative regulation of cell growth; negative regulation of cell proliferation; response to unfolded protein; protein folding | |
| DNAJB4 | response to heat; response to unfolded protein; protein folding | |
| DNAJB5 | negative regulation of transcription from RNA polymerase II promoter; protein folding; response to unfolded protein | |
| DNAJB8 | protein folding | |
| DNAJB9 | protein folding; endoplasmic reticulum unfolded protein response; ER-associated protein catabolic process; activation of signaling protein activity involved in unfolded protein response | |
| DNAJC11 | protein folding | |
| DNAJC12 | protein folding | |
| DNAJC13 | - | |
| DNAJC16 | protein folding; cell redox homeostasis | |
| DNAJC17 | protein folding | |
| DNAJC2 | G2 phase of mitotic cell cycle; DNA replication; chromatin modification; negative regulation of cell growth; positive regulation of transcription, DNA-dependent; 'de novo' cotranslational protein folding | |
| DNAJC21 | protein folding | |
| DNAJC25 | protein folding | |
| DNAJC28 | - | |
| DNAJC6 | post-Golgi vesicle-mediated transport; cellular membrane organization | |
| DNALI1 | single fertilization; cellular component movement | |
| DNASE1 | apoptotic process; DNA catabolic process | |
| DNASE1L2 | DNA catabolic process; DNA metabolic process | |
| DNHD1 | microtubule-based movement | |
| DNM1 | GTP catabolic process; receptor-mediated endocytosis; endocytosis; endosome organization | |
| DNM1L | dynamin polymerization involved in mitochondrial fission; apoptotic process; mitochondrial fragmentation involved in apoptosis; positive regulation of intrinsic apoptotic signaling pathway; peroxisome fission; positive regulation of mitochondrial fission; membrane fission involved in mitochondrial fission; positive regulation of protein secretion; cellular component disassembly involved in apoptosis | |
| DNM2 | endocytosis; synaptic vesicle transport; positive regulation of transcription, DNA-dependent; positive regulation of apoptotic process; transferrin transport; receptor internalization; cellular membrane organization; signal transduction; post-Golgi vesicle-mediated transport; regulation of transcription, DNA-dependent; GTP catabolic process; G2/M transition of mitotic cell cycle | |
| DNMBP | regulation of Rho protein signal transduction; intracellular signal transduction | |
| DNMT1 | regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; C-5 methylation of cytosine; cellular response to amino acid stimulus; negative regulation of histone H3-K9 methylation; chromatin modification; positive regulation of histone H3-K4 methylation; maintenance of DNA methylation; positive regulation of gene expression; gene silencing; DNA methylation | |
| DNMT3A | S-adenosylmethioninamine metabolic process; methylation-dependent chromatin silencing; regulation of gene expression by genetic imprinting; spermatogenesis; DNA methylation on cytosine within a CG sequence; chromatin modification; DNA methylation involved in embryo development; DNA methylation involved in gamete generation; hypermethylation of CpG island; S-adenosylhomocysteine metabolic process; cellular response to amino acid stimulus; C-5 methylation of cytosine; DNA methylation; negative regulation of transcription from RNA polymerase II promoter | |
| DNMT3B | positive regulation of histone H3-K4 methylation; negative regulation of histone H3-K9 methylation; positive regulation of gene expression; protein complex localization; response to drug; DNA methylation involved in embryo development; positive regulation of neuron differentiation; S-adenosylmethioninamine metabolic process; S-adenosylhomocysteine metabolic process; negative regulation of gene expression, epigenetic; C-5 methylation of cytosine; cellular response to amino acid stimulus; DNA methylation on cytosine within a CG sequence; response to ionizing radiation; regulation of gene expression by genetic imprinting; methylation-dependent chromatin silencing; DNA methylation; negative regulation of transcription from RNA polymerase II promoter | |
| DNPEP | peptide metabolic process; proteolysis | |
| DNTT | DNA modification | |
| DNTTIP1 | - | |
| DOCK11 | regulation of catalytic activity; blood coagulation | |
| DOCK2 | chemotaxis; regulation of defense response to virus by virus; alpha-beta T cell proliferation; negative thymic T cell selection; positive thymic T cell selection; actin cytoskeleton organization; viral reproduction; membrane raft polarization; establishment of T cell polarity; immunological synapse formation | |
| DOCK7 | multicellular organismal development; microtubule cytoskeleton organization; nervous system development; axonogenesis; cell differentiation; neuron projection development; activation of Rac GTPase activity; positive regulation of peptidyl-serine phosphorylation; establishment of neuroblast polarity | |
| DOCK8 | blood coagulation | |
| DOK2 | blood coagulation; signal transduction; cell surface receptor signaling pathway; leukocyte migration; Ras protein signal transduction | |
| DOK3 | Ras protein signal transduction | |
| DOK5 | nervous system development; transmembrane receptor protein tyrosine kinase signaling pathway; MAPK cascade | |
| DOK6 | - | |
| DOK7 | positive regulation of protein tyrosine kinase activity | |
| DOLK | protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification; dolichyl monophosphate biosynthetic process; dolichyl diphosphate biosynthetic process; dolichol-linked oligosaccharide biosynthetic process | |
| DOPEY1 | endoplasmic reticulum organization; protein transport; Golgi to endosome transport | |
| DOPEY2 | endoplasmic reticulum organization; Golgi to endosome transport; multicellular organismal development; protein transport | |
| DOT1L | regulation of transcription regulatory region DNA binding; regulation of JAK-STAT cascade; histone lysine methylation; chromatin modification | |
| DPAGT1 | metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein N-linked glycosylation; UDP-N-acetylglucosamine metabolic process; protein N-linked glycosylation via asparagine; dolichol biosynthetic process; post-translational protein modification; cellular protein metabolic process; protein oligomerization | |
| DPCD | - | |
| DPEP1 | cellular response to calcium ion; cellular lactam catabolic process; cellular response to nitric oxide; homocysteine metabolic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of cell migration; antibiotic metabolic process; cellular response to drug; glutathione metabolic process; proteolysis | |
| DPEP2 | proteolysis; prostanoid metabolic process; leukotriene biosynthetic process; small molecule metabolic process | |
| DPF2 | induction of apoptosis by extracellular signals; induction of apoptosis; apoptotic process; regulation of transcription, DNA-dependent | |
| DPH1 | peptidyl-diphthamide biosynthetic process from peptidyl-histidine; cell proliferation; translation | |
| DPH6 | - | |
| DPM1 | cellular protein metabolic process; post-translational protein modification; protein O-linked mannosylation; protein mannosylation; GDP-mannose metabolic process; dolichol metabolic process; protein N-linked glycosylation via asparagine; GPI anchor biosynthetic process; C-terminal protein lipidation; dolichol-linked oligosaccharide biosynthetic process | |
| DPP10 | proteolysis | |
| DPP4 | endothelial cell migration; response to hypoxia; regulation of T cell mediated immunity; proteolysis; cell adhesion; positive regulation of cell proliferation; negative regulation of extracellular matrix disassembly; T cell costimulation; regulation of cell-cell adhesion mediated by integrin; T cell activation; establishment of localization | |
| DPP7 | proteolysis | |
| DPP8 | proteolysis; immune response | |
| DPPA3 | embryonic cleavage | |
| DPPA5 | multicellular organismal development | |
| DPY19L4 | - | |
| DPYD | pyrimidine base metabolic process; pyrimidine base catabolic process; thymine catabolic process; uracil catabolic process; thymidine catabolic process; UMP biosynthetic process; small molecule metabolic process; pyrimidine nucleoside catabolic process; nucleobase-containing small molecule metabolic process; purine base catabolic process | |
| DPYS | nucleobase-containing small molecule metabolic process; pyrimidine base metabolic process; pyrimidine base catabolic process; thymine catabolic process; uracil catabolic process; beta-alanine metabolic process; small molecule metabolic process; pyrimidine nucleoside catabolic process; protein homotetramerization | |
| DPYSL2 | spinal cord development; synaptic vesicle transport; cytoskeleton organization; signal transduction; multicellular organismal development; nervous system development; axon guidance; brain development; positive regulation of glutamate secretion; pyrimidine base catabolic process; olfactory bulb development; cell differentiation; response to cocaine; response to drug; regulation of neuron differentiation; nucleobase-containing compound metabolic process; response to amphetamine | |
| DPYSL3 | pyrimidine base catabolic process; axon guidance; positive regulation of neuron projection development; negative regulation of neuron projection development; negative regulation of cell migration; response to axon injury; actin filament bundle assembly; protein homooligomerization; positive regulation of filopodium assembly; actin crosslink formation; cellular response to cytokine stimulus | |
| DPYSL4 | axon guidance; pyrimidine base catabolic process; nervous system development | |
| DQX1 | - | |
| DRAM1 | apoptotic process; autophagy | |
| DRAXIN | - | |
| DRC1 | - | |
| DRC7 | ciliary or flagellar motility; spermatogenesis; cell differentiation | |
| DRD1 | positive regulation of release of sequestered calcium ion into cytosol; negative regulation of circadian sleep/wake cycle, sleep; dopamine metabolic process; eating behavior; positive regulation of potassium ion transport; regulation of ion transport; glucose import; sensitization; behavioral response to cocaine; regulation of long-term neuronal synaptic plasticity; long term synaptic depression; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; regulation of dopamine uptake; response to drug; positive regulation of synaptic transmission, glutamatergic; prepulse inhibition; activation of phospholipase C activity by dopamine receptor signaling pathway; long-term synaptic potentiation; mating behavior; synaptic transmission, dopaminergic; response to amphetamine; negative regulation of protein kinase activity; protein import into nucleus; adult walking behavior; locomotory behavior; grooming behavior; regulation of dopamine metabolic process; behav | |
| DRD2 | positive regulation of renal sodium excretion; positive regulation of G-protein coupled receptor protein signaling pathway; regulation of phosphoprotein phosphatase activity; pigmentation; regulation of MAPK cascade; response to morphine; regulation of potassium ion transport; response to drug; dopamine metabolic process; negative regulation of circadian sleep/wake cycle, sleep; response to cocaine; positive regulation of multicellular organism growth; regulation of synaptic transmission, GABAergic; release of sequestered calcium ion into cytosol; positive regulation of ERK1 and ERK2 cascade; negative regulation of dopamine receptor signaling pathway; activation of phospholipase C activity by dopamine receptor signaling pathway; prepulse inhibition; positive regulation of growth hormone secretion; negative regulation of synaptic transmission, glutamatergic; negative regulation of calcium ion transport via voltage-gated calcium channel activity; negative regulation of protein kinase B signaling cascade; positi | |
| DRD3 | response to drug; response to morphine; regulation of circadian sleep/wake cycle, sleep; response to ethanol; negative regulation of blood pressure; positive regulation of mitosis; positive regulation of transcription from RNA polymerase II promoter; acid secretion; behavioral response to cocaine; negative regulation of oligodendrocyte differentiation; visual learning; arachidonic acid secretion; negative regulation of protein secretion; musculoskeletal movement, spinal reflex action; regulation of dopamine uptake; negative regulation of protein kinase B signaling cascade; prepulse inhibition; negative regulation of dopamine receptor signaling pathway; positive regulation of dopamine receptor signaling pathway; response to cocaine; cellular calcium ion homeostasis; dopamine metabolic process; G-protein coupled receptor internalization; regulation of blood volume by renin-angiotensin; response to amphetamine; synaptic transmission, dopaminergic; negative regulation of transcription from RNA polymerase II promo | |
| DRD4 | fear response; regulation of neurotransmitter secretion; behavioral response to cocaine; behavioral response to ethanol; arachidonic acid secretion; negative regulation of protein secretion; regulation of calcium-mediated signaling; positive regulation of dopamine uptake; negative regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of inhibitory postsynaptic membrane potential; positive regulation of sodium:hydrogen antiporter activity; regulation of dopamine metabolic process; activation of MAPK activity; behavioral fear response; synaptic transmission, dopaminergic; response to amphetamine; cellular calcium ion homeostasis; negative regulation of adenylate cyclase activity; inhibition of adenylate cyclase activity by dopamine receptor signaling pathway; dopamine receptor signaling pathway; adult locomotory behavior; dopamine metabolic process; social behavior; response to histamine; positive regulation of kinase activity; negative regulation of cAMP biosynthetic proces | |
| DRG2 | signal transduction | |
| DRP2 | central nervous system development | |
| DSC1 | cell adhesion; homophilic cell adhesion | |
| DSC2 | cell adhesion; homophilic cell adhesion | |
| DSC3 | protein stabilization; cell adhesion; homophilic cell adhesion | |
| DSCAM | positive regulation of axon extension involved in axon guidance; cell adhesion; negative regulation of cell adhesion; nervous system development; dendrite morphogenesis; positive regulation of phosphorylation; dendrite self-avoidance; post-embryonic retina morphogenesis in camera-type eye; locomotory behavior | |
| DSCAML1 | homophilic cell adhesion; central nervous system development; dendrite self-avoidance; dorsal/ventral pattern formation; brain development; embryonic skeletal system morphogenesis; axonogenesis; negative regulation of cell adhesion; cell fate determination | |
| DSCC1 | post-translational protein acetylation; maintenance of mitotic sister chromatid cohesion; cell cycle; regulation of DNA replication | |
| DSEL | - | |
| DSG1 | apoptotic process; cellular component disassembly involved in apoptosis; cell-cell junction assembly; homophilic cell adhesion; cell-cell adhesion; calcium-dependent cell-cell adhesion; protein stabilization | |
| DSG2 | homophilic cell adhesion; execution phase of apoptosis; cellular component disassembly involved in apoptosis; apoptotic process; cell adhesion | |
| DSG3 | apoptotic process; cellular component disassembly involved in apoptosis; cell adhesion; homophilic cell adhesion | |
| DSG4 | homophilic cell adhesion; cell adhesion | |
| DSP | cellular component disassembly involved in apoptosis; skin development; wound healing; adherens junction organization; keratinocyte differentiation; peptide cross-linking; cell-cell adhesion; epidermis development; apoptotic process | |
| DSPP | multicellular organismal development; biomineral tissue development; cellular response to cell-matrix adhesion; skeletal system development; ossification | |
| DST | cell motility; intracellular transport; intermediate filament cytoskeleton organization; hemidesmosome assembly; cytoplasmic microtubule organization; regulation of microtubule polymerization or depolymerization; maintenance of cell polarity; response to wounding; retrograde axon cargo transport; axonogenesis; cell adhesion; cell cycle arrest; cytoskeleton organization; microtubule cytoskeleton organization; integrin-mediated signaling pathway | |
| DSTYK | - | |
| DTNA | neuromuscular synaptic transmission; synaptic transmission; signal transduction; striated muscle contraction | |
| DTNBP1 | actin cytoskeleton reorganization; regulation of dopamine receptor signaling pathway; platelet dense granule organization; response to stimulus; neuron projection morphogenesis; post-Golgi vesicle-mediated transport; organelle organization; blood coagulation; cellular membrane organization; neuron projection development | |
| DTX1 | transcription from RNA polymerase II promoter; negative regulation of neuron differentiation; negative regulation of T cell differentiation; glial cell differentiation; regulation of Notch signaling pathway; cell surface receptor signaling pathway; transcription, DNA-dependent | |
| DTX3L | histone monoubiquitination; response to DNA damage stimulus; chromatin modification | |
| DUOX1 | hydrogen peroxide catabolic process; hormone biosynthetic process; hydrogen peroxide biosynthetic process; superoxide anion generation; response to oxidative stress; cytokine-mediated signaling pathway; cuticle development; oxidation-reduction process; response to cAMP | |
| DUOX2 | bone mineralization; response to oxidative stress; multicellular organism growth; fertilization; response to virus; cytokine-mediated signaling pathway; hydrogen peroxide catabolic process; inner ear development; oxidation-reduction process; thyroid hormone metabolic process; cuticle development; adenohypophysis morphogenesis; response to cAMP; hormone biosynthetic process; thyroid gland development | |
| DUOXA1 | protein transport | |
| DUOXA2 | protein transport | |
| DUPD1 | protein dephosphorylation | |
| DUS3L | tRNA processing | |
| DUSP10 | negative regulation of respiratory burst involved in inflammatory response; negative regulation of JNK cascade; regulation of innate immune response; negative regulation of JUN kinase activity; negative regulation of stress-activated MAPK cascade; response to organic substance; JNK cascade; response to stress; protein dephosphorylation; regulation of adaptive immune response; inactivation of MAPK activity; response to lipopolysaccharide | |
| DUSP13 | protein dephosphorylation; meiosis; spermatogenesis | |
| DUSP16 | protein dephosphorylation; dephosphorylation; MAPK export from nucleus; MAPK phosphatase export from nucleus, leptomycin B sensitive; inactivation of MAPK activity | |
| DUSP21 | peptidyl-tyrosine dephosphorylation | |
| DUSP22 | multicellular organismal development; positive regulation of JNK cascade; inactivation of MAPK activity; regulation of cell proliferation; cell proliferation; protein dephosphorylation; apoptotic process; transforming growth factor beta receptor signaling pathway | |
| DUSP27 | protein dephosphorylation | |
| DUSP3 | toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; peptidyl-tyrosine dephosphorylation; TRIF-dependent toll-like receptor signaling pathway; negative regulation of MAPK cascade; innate immune response; positive regulation of mitotic cell cycle; negative regulation of JNK cascade; nerve growth factor receptor signaling pathway; negative regulation of T cell receptor signaling pathway; negative regulation of T cell activation; stress-activated MAPK cascade; negative regulation of ERK1 and ERK2 cascade; inactivation of MAPK activity; in utero embryonic development | |
| DUSP4 | TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; response to organic substance; Toll signaling pathway; protein dephosphorylation; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; endoderm formation; inactivation of MAPK activity; MAPK cascade; innate immune response; nerve growth factor receptor signaling pathway; stress-activated MAPK cascade | |
| DUSP5 | inactivation of MAPK activity; endoderm formation; protein dephosphorylation; peptidyl-tyrosine dephosphorylation; negative regulation of transcription, DNA-dependent | |
| DUSP6 | inactivation of MAPK activity; Toll signaling pathway; negative regulation of protein phosphorylation; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; response to organic cyclic compound; dorsal/ventral pattern formation; MyD88-independent toll-like receptor signaling pathway; cell differentiation; regulation of endodermal cell fate specification; peptidyl-tyrosine dephosphorylation; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; regulation of fibroblast growth factor receptor signaling pathway; response to drug; response to growth factor stimulus; positive regulation of apoptotic process; innate immune response; nerve growth factor receptor signaling pathway; stress-activated MAPK cascade; response to nitrosative stress; regulation of heart growth; negative regulation of ERK1 and ERK2 cascade | |
| DUSP7 | toll-like receptor signaling pathway; inactivation of MAPK activity; stress-activated MAPK cascade; nerve growth factor receptor signaling pathway; innate immune response; negative regulation of MAP kinase activity; TRIF-dependent toll-like receptor signaling pathway; peptidyl-tyrosine dephosphorylation; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; Toll signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway | |
| DUT | small molecule metabolic process; DNA replication; pyrimidine base metabolic process; nucleobase-containing compound metabolic process; nucleotide metabolic process; dUTP metabolic process; pyrimidine nucleoside biosynthetic process; nucleobase-containing small molecule metabolic process | |
| DUXA | - | |
| DVL1 | positive regulation of neuron projection development; social behavior; protein localization to nucleus; negative regulation of protein binding; cytoplasmic microtubule organization; positive regulation of Wnt receptor signaling pathway; intracellular signal transduction; convergent extension involved in neural plate elongation; neural tube development; dendrite morphogenesis; positive regulation of canonical Wnt receptor signaling pathway; planar cell polarity pathway involved in neural tube closure; cochlea morphogenesis; skeletal muscle acetylcholine-gated channel clustering; prepulse inhibition; Wnt receptor signaling pathway, planar cell polarity pathway; canonical Wnt receptor signaling pathway; convergent extension; synapse organization; protein localization to microtubule; receptor clustering; positive regulation of transcription, DNA-dependent; collateral sprouting; axon extension; heart development; neuromuscular junction development; regulation of neurotransmitter levels; negative regulation of prot | |
| DYM | - | |
| DYNC1H1 | G2/M transition of mitotic cell cycle; mitotic cell cycle; transport; microtubule-based movement; mitotic spindle organization; cytoplasmic mRNA processing body assembly; stress granule assembly | |
| DYNC1I1 | transport; vesicle transport along microtubule | |
| DYNC1LI2 | transport | |
| DYNC2LI1 | multicellular organismal development; determination of left/right symmetry; cell projection organization; cilium assembly | |
| DYNLL1 | interspecies interaction between organisms; microtubule-based process; apoptotic process; transport; regulation of transcription, DNA-dependent; mitotic cell cycle; G2/M transition of mitotic cell cycle; anatomical structure morphogenesis; actin cytoskeleton organization; female gamete generation; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; negative regulation of phosphorylation | |
| DYNLRB2 | microtubule-based movement; transport | |
| DYNLT3 | transport; cell cycle; mitosis; regulation of mitotic cell cycle; cell division | |
| DYRK1A | mitotic cell cycle; protein phosphorylation; nervous system development; peptidyl-tyrosine phosphorylation; protein autophosphorylation | |
| DYRK1B | positive regulation of transcription, DNA-dependent; protein phosphorylation; myoblast fusion | |
| DYRK3 | protein phosphorylation; erythrocyte differentiation | |
| DYRK4 | protein phosphorylation | |
| DYSF | - | |
| DYX1C1 | regulation of intracellular estrogen receptor signaling pathway; neuron migration; nervous system development; regulation of proteasomal protein catabolic process | |
| DZIP1 | germ cell development; spermatogenesis; cell differentiation; multicellular organismal development | |
| DZIP1L | - | |
| DZIP3 | protein polyubiquitination | |
| E2F2 | mitotic cell cycle; regulation of cell cycle; apoptotic process; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; G1 phase of mitotic cell cycle | |
| E2F6 | regulation of transcription involved in G1/S phase of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; cell cycle | |
| E2F7 | negative regulation of cell proliferation; cell cycle | |
| E2F8 | cell cycle | |
| E4F1 | regulation of growth; interspecies interaction between organisms; cell cycle; cell division; regulation of cell cycle process; regulation of mitotic cell cycle, embryonic; embryo development; mitotic cell cycle arrest; cell proliferation; regulation of transcription, DNA-dependent; DNA replication; negative regulation of transcription from RNA polymerase II promoter; mitosis | |
| EAF1 | regulation of transcription, DNA-dependent | |
| EAPP | positive regulation of cell proliferation; positive regulation of transcription elongation from RNA polymerase II promoter; negative regulation of transcription elongation from RNA polymerase II promoter | |
| EBF1 | multicellular organismal development; positive regulation of transcription, DNA-dependent | |
| EBF2 | multicellular organismal development; regulation of transcription, DNA-dependent | |
| EBNA1BP2 | ribosome biogenesis | |
| ECD | transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of glycolysis | |
| ECE2 | proteolysis; cell-cell signaling; peptide hormone processing; cardioblast differentiation; heart development; brain development | |
| ECEL1 | intracellular signal transduction; metabolic process; neuropeptide signaling pathway; proteolysis | |
| ECHDC1 | - | |
| ECHDC2 | lipid metabolic process; fatty acid metabolic process | |
| ECHS1 | small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation; fatty acid metabolic process | |
| ECI1 | fatty acid metabolic process; fatty acid beta-oxidation; cellular lipid metabolic process; small molecule metabolic process | |
| ECM1 | negative regulation of bone mineralization; positive regulation of angiogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; biomineral tissue development; negative regulation of peptidase activity; ossification; positive regulation of endothelial cell proliferation; signal transduction | |
| ECT2L | regulation of Rho protein signal transduction | |
| EDA2R | cell differentiation; tumor necrosis factor-mediated signaling pathway; positive regulation of JNK cascade; positive regulation of NF-kappaB transcription factor activity; embryo development; epidermis development | |
| EDAR | apoptotic process; hair follicle development; signal transduction; multicellular organismal development; epidermis development; cell differentiation; positive regulation of NF-kappaB import into nucleus; odontogenesis of dentin-containing tooth; pigmentation; salivary gland cavitation | |
| EDARADD | hair follicle development; odontogenesis of dentin-containing tooth; cell differentiation; signal transduction; trachea gland development; multicellular organismal development | |
| EDC4 | RNA metabolic process; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; gene expression | |
| EDDM3B | spermatid development | |
| EDEM1 | activation of signaling protein activity involved in unfolded protein response; response to unfolded protein; protein folding; post-translational protein modification; cellular protein metabolic process; endoplasmic reticulum unfolded protein response; ER-associated protein catabolic process; protein N-linked glycosylation via asparagine | |
| EDEM3 | response to unfolded protein; protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification; proteasomal ubiquitin-dependent protein catabolic process; protein folding; glycoprotein catabolic process | |
| EDIL3 | cell adhesion; multicellular organismal development; positive regulation of cell-substrate adhesion | |
| EDN3 | regulation of vasoconstriction; peptide hormone secretion; neuron differentiation; vein smooth muscle contraction; melanocyte differentiation; regulation of cell migration; neutrophil chemotaxis; vasoconstriction; positive regulation of MAP kinase activity; positive regulation of mitosis; positive regulation of hormone secretion; negative regulation of hormone secretion; regulation of neurotransmitter secretion; inositol phosphate-mediated signaling; regulation of developmental pigmentation; positive regulation of heart rate; artery smooth muscle contraction; neural crest cell migration; positive regulation of leukocyte chemotaxis; regulation of systemic arterial blood pressure by endothelin; signal transduction; cell surface receptor signaling pathway; cell-cell signaling; multicellular organismal development; blood circulation; positive regulation of cell proliferation | |
| EDNRA | fibroblast proliferation; artery smooth muscle contraction; response to morphine; penile erection; negative regulation of apoptotic process; positive regulation of odontogenesis; vasoconstriction; specification of segmental identity, mandibular segment; response to lipopolysaccharide; negative regulation of cAMP biosynthetic process; sensory perception of pain; glucose transport; positive regulation of cell proliferation; smooth muscle cell proliferation; regulation of epithelial cell proliferation; positive regulation of inflammatory response; positive regulation of release of sequestered calcium ion into cytosol; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; positive regulation of calcium ion transport; maternal process involved in parturition; head development; positive regulation of ERK1 and ERK2 cascade; cellular response to mechanical stimulus; positive regulation of neutrophil chemotaxis; positive regulation of kidney development; neur | |
| EEA1 | synaptic vesicle to endosome fusion; vesicle fusion; endocytosis; early endosome to late endosome transport | |
| EEF1A2 | response to inorganic substance; anti-apoptosis; translation | |
| EEF1D | translation; translational elongation; signal transduction; gene expression; positive regulation of I-kappaB kinase/NF-kappaB cascade; cellular protein metabolic process | |
| EEF1E1 | positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of apoptotic process; gene expression; negative regulation of cell proliferation; tRNA aminoacylation for protein translation | |
| EEFSEC | selenocysteine incorporation; translational elongation; GTP catabolic process | |
| EEPD1 | DNA repair | |
| EFCAB1 | - | |
| EFCAB13 | - | |
| EFCAB2 | - | |
| EFCAB6 | regulation of transcription, DNA-dependent | |
| EFEMP1 | regulation of transcription, DNA-dependent; epidermal growth factor receptor signaling pathway; visual perception; peptidyl-tyrosine phosphorylation; negative regulation of chondrocyte differentiation | |
| EFEMP2 | blood coagulation | |
| EFHC1 | - | |
| EFHD1 | neuron projection development | |
| EFNA3 | cell-cell signaling; ephrin receptor signaling pathway | |
| EFNA4 | cell-cell signaling | |
| EFNB3 | cell differentiation; ephrin receptor signaling pathway; interspecies interaction between organisms; axon choice point recognition; nervous system development; adult walking behavior; multicellular organismal development; cell-cell signaling | |
| EFS | cell adhesion; intracellular signal transduction | |
| EFTUD2 | nuclear mRNA splicing, via spliceosome; GTP catabolic process; gene expression; RNA splicing; mRNA processing | |
| EGFLAM | positive regulation of cell-substrate adhesion; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; extracellular matrix organization | |
| EGFR | positive regulation of catenin import into nucleus; negative regulation of protein catabolic process; negative regulation of epidermal growth factor receptor signaling pathway; positive regulation of phosphorylation; activation of phospholipase A2 activity by calcium-mediated signaling; negative regulation of apoptotic process; positive regulation of MAP kinase activity; positive regulation of nitric oxide biosynthetic process; positive regulation of DNA repair; positive regulation of DNA replication; protein autophosphorylation; positive regulation of fibroblast proliferation; digestive tract morphogenesis; positive regulation of epithelial cell proliferation; regulation of peptidyl-tyrosine phosphorylation; regulation of nitric-oxide synthase activity; protein insertion into membrane; positive regulation of protein kinase B signaling cascade; morphogenesis of an epithelial fold; response to UV-A; positive regulation of cell migration; cell morphogenesis; ossification; embryonic placenta development; hair fo | |
| EGR1 | BMP signaling pathway; T cell differentiation; cytokine-mediated signaling pathway; response to glucose stimulus; learning or memory; transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; regulation of protein sumoylation; response to insulin stimulus; negative regulation of canonical Wnt receptor signaling pathway; positive regulation of glomerular metanephric mesangial cell proliferation; glomerular mesangial cell proliferation; cellular response to mycophenolic acid; cellular response to heparin; cellular response to gamma radiation; interleukin-1-mediated signaling pathway; type I interferon-mediated signaling pathway; regulation of long-term neuronal synaptic plasticity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent | |
| EGR2 | rhombomere 5 formation; regulation of neuronal synaptic plasticity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; fat cell differentiation; myelination; brain segmentation; response to insulin stimulus; regulation of ossification; rhombomere 3 formation; facial nerve structural organization; Schwann cell differentiation; motor axon guidance; rhythmic behavior; learning or memory; peripheral nervous system development; brain development; protein export from nucleus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; rhombomere 3 development | |
| EGR4 | regulation of transcription, DNA-dependent; positive regulation of cell proliferation | |
| EHBP1 | - | |
| EHD1 | intracellular protein transport; endocytic recycling; low-density lipoprotein particle clearance; endocytosis; blood coagulation; positive regulation of cholesterol storage; cholesterol homeostasis; protein homooligomerization | |
| EHMT1 | peptidyl-lysine dimethylation; histone lysine methylation; negative regulation of transcription, DNA-dependent; histone H3-K9 methylation; histone H3-K27 methylation; peptidyl-lysine monomethylation; histone methylation; chromatin modification; embryo development; DNA methylation; negative regulation of transcription from RNA polymerase II promoter | |
| EID2B | muscle organ development; cell differentiation; regulation of transcription, DNA-dependent; multicellular organismal development | |
| EIF1AD | - | |
| EIF2AK1 | protein autophosphorylation; response to stress; negative regulation of cell proliferation; response to external stimulus; regulation of eIF2 alpha phosphorylation by heme; negative regulation of translation; negative regulation of translational initiation by iron; negative regulation of hemoglobin biosynthetic process; protoporphyrinogen IX metabolic process | |
| EIF2AK3 | skeletal system development; ossification; chondrocyte development; protein phosphorylation; activation of cysteine-type endopeptidase activity involved in apoptotic process; response to stress; lactation; negative regulation of translational initiation in response to stress; negative regulation of myelination; endocrine pancreas development; endoplasmic reticulum unfolded protein response; bone mineralization; insulin secretion; calcium-mediated signaling; regulation of fatty acid metabolic process; positive regulation of protein binding; negative regulation of translation; positive regulation of signal transduction; SREBP-mediated signaling pathway; endoplasmic reticulum organization; activation of signaling protein activity involved in unfolded protein response; response to unfolded protein; ER overload response; response to endoplasmic reticulum stress; fat cell differentiation; protein homooligomerization; protein autophosphorylation; virus-infected cell apoptosis; insulin-like growth factor receptor sig | |
| EIF2AK4 | negative regulation of translation; endoplasmic reticulum unfolded protein response; regulation of translational initiation in response to stress; protein phosphorylation; regulation of translational initiation; cellular response to starvation | |
| EIF2B1 | translation; translational initiation; regulation of translational initiation; response to heat; response to glucose stimulus; gene expression; oligodendrocyte development; response to peptide hormone stimulus; cellular metabolic process; cellular protein metabolic process; cellular response to stimulus | |
| EIF2B2 | ovarian follicle development; gene expression; response to heat; cellular metabolic process; cellular protein metabolic process; cellular response to stimulus; response to peptide hormone stimulus; myelination; oligodendrocyte development; response to glucose stimulus; central nervous system development; regulation of translational initiation; translational initiation; translation | |
| EIF2B4 | translational initiation; cellular protein metabolic process; cellular metabolic process; response to peptide hormone stimulus; myelination; negative regulation of translational initiation in response to stress; cellular response to stimulus; ovarian follicle development; translation; regulation of translation; response to heat; response to glucose stimulus; gene expression; oligodendrocyte development; negative regulation of translational initiation | |
| EIF2D | intracellular protein transport; translational initiation | |
| EIF2S1 | activation of signaling protein activity involved in unfolded protein response; endoplasmic reticulum unfolded protein response; regulation of translational initiation in response to stress; cellular protein metabolic process; protein autophosphorylation; gene expression; regulation of translation; translational initiation; translation | |
| EIF3A | cellular protein metabolic process; formation of translation initiation complex; translation; translational initiation; gene expression | |
| EIF3B | gene expression; translation; translational initiation; regulation of translational initiation; cellular protein metabolic process | |
| EIF3D | formation of translation initiation complex; translation; translational initiation; gene expression; cellular protein metabolic process | |
| EIF3H | gene expression; translation; cellular protein metabolic process; regulation of translational initiation; translational initiation | |
| EIF3L | translational initiation | |
| EIF3M | translational initiation | |
| EIF4A1 | organ regeneration; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cellular protein metabolic process; cytokine-mediated signaling pathway; nuclear-transcribed mRNA poly(A) tail shortening; translation; translational initiation; gene expression; RNA metabolic process; mRNA metabolic process | |
| EIF4E | translation; positive regulation of mitotic cell cycle; interspecies interaction between organisms; cellular protein metabolic process; cytokine-mediated signaling pathway; mRNA metabolic process; RNA metabolic process; gene expression; insulin receptor signaling pathway; regulation of translation; translational initiation; mRNA export from nucleus; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; G1/S transition of mitotic cell cycle | |
| EIF4E2 | translation; regulation of translation; cytokine-mediated signaling pathway | |
| EIF4EBP1 | cellular protein metabolic process; G1/S transition of mitotic cell cycle; translation; translational initiation; insulin receptor signaling pathway; gene expression; negative regulation of protein complex assembly; TOR signaling cascade; positive regulation of mitotic cell cycle; negative regulation of translational initiation | |
| EIF4G1 | interspecies interaction between organisms; gene expression; cellular protein metabolic process; cytokine-mediated signaling pathway; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; nuclear-transcribed mRNA poly(A) tail shortening; translation; translational initiation; regulation of translational initiation; cell death; insulin receptor signaling pathway; RNA metabolic process | |
| EIF4G2 | translation; translational initiation; regulation of translational initiation; cell cycle arrest; cell death; RNA metabolic process; cytokine-mediated signaling pathway | |
| EIF4G3 | interspecies interaction between organisms; cytokine-mediated signaling pathway; RNA metabolic process; regulation of translational initiation; translation | |
| EIF5A2 | positive regulation of translational elongation; translational frameshifting; spermatogenesis; mRNA transport; positive regulation of cell proliferation; peptidyl-lysine modification to hypusine; polyamine homeostasis; protein transport; post-translational protein modification; cellular protein metabolic process; positive regulation of translational termination | |
| EIF5B | regulation of translational initiation; translational initiation; translation; gene expression; cellular protein metabolic process | |
| ELAC1 | tRNA 3'-trailer cleavage; tRNA processing | |
| ELAVL1 | mRNA stabilization; multicellular organismal development; gene expression; RNA metabolic process; mRNA metabolic process; positive regulation of translation; 3'-UTR-mediated mRNA stabilization | |
| ELAVL3 | cell differentiation; nervous system development; multicellular organismal development | |
| ELAVL4 | mRNA processing; RNA processing | |
| ELF1 | negative regulation of T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of cytokine production | |
| ELF2 | positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter | |
| ELF3 | extracellular matrix organization; regulation of transcription, DNA-dependent; blastocyst development; transcription from RNA polymerase II promoter; inflammatory response; multicellular organismal development; epidermis development; anatomical structure morphogenesis; embryo development; epithelial cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; mammary gland involution | |
| ELF5 | ectoderm development; transcription from RNA polymerase II promoter; mammary gland epithelial cell differentiation; cell proliferation | |
| ELFN2 | negative regulation of phosphatase activity | |
| ELL | positive regulation of viral transcription; positive regulation of transcription elongation, DNA-dependent; viral reproduction; negative regulation of phosphatase activity; gene expression; transcription elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; in utero embryonic development | |
| ELL3 | positive regulation of transcription elongation, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; spermatogenesis; regulation of transcription, DNA-dependent; transcription elongation, DNA-dependent | |
| ELMO1 | regulation of defense response to virus by virus; cellular component movement; viral reproduction; Rac protein signal transduction; actin cytoskeleton organization; apoptotic process; phagocytosis, engulfment | |
| ELMO3 | phagocytosis; apoptotic process | |
| ELMOD3 | phagocytosis | |
| ELN | respiratory gaseous exchange; blood circulation; cell proliferation; organ morphogenesis | |
| ELOVL4 | fatty acid biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; very long-chain fatty acid biosynthetic process; long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; fatty acid elongation, saturated fatty acid; detection of visible light | |
| ELOVL7 | long-chain fatty-acyl-CoA biosynthetic process; very long-chain fatty acid biosynthetic process; cellular lipid metabolic process; small molecule metabolic process; fatty acid elongation, polyunsaturated fatty acid; triglyceride biosynthetic process; fatty acid elongation, saturated fatty acid; fatty acid biosynthetic process | |
| ELSPBP1 | single fertilization | |
| EMC1 | - | |
| EMCN | - | |
| EMILIN1 | extracellular matrix organization; positive regulation of cell-substrate adhesion; cell adhesion | |
| EMILIN2 | cell adhesion | |
| EMILIN3 | - | |
| EML1 | - | |
| EML2 | visual perception; sensory perception of sound | |
| EML3 | - | |
| EML4 | microtubule-based process; mitosis | |
| EMP1 | multicellular organismal development; cell proliferation; epidermis development; cell growth | |
| EMP2 | cell proliferation | |
| EMSY | DNA repair; regulation of transcription, DNA-dependent; chromatin modification | |
| EN1 | skeletal system development; multicellular organismal development; anatomical structure morphogenesis; dorsal/ventral pattern formation; proximal/distal pattern formation; midbrain development; hindbrain development; midbrain-hindbrain boundary development; embryonic forelimb morphogenesis; neuron development; pigmentation; positive regulation of transcription from RNA polymerase II promoter | |
| ENAM | odontogenesis; bone mineralization | |
| ENC1 | multicellular organismal development; nervous system development | |
| ENDOG | response to tumor necrosis factor; response to antibiotic; positive regulation of apoptotic process; in utero embryonic development; DNA fragmentation involved in apoptotic nuclear change | |
| ENDOU | female pregnancy; immune response; proteolysis | |
| ENGASE | metabolic process | |
| ENKUR | - | |
| ENO1 | negative regulation of transcription, DNA-dependent; small molecule metabolic process; negative regulation of cell growth; response to virus; glycolysis; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process; negative regulation of transcription from RNA polymerase II promoter | |
| ENO2 | carbohydrate metabolic process; glucose metabolic process; gluconeogenesis; glycolysis; small molecule metabolic process | |
| ENO3 | glucose metabolic process; small molecule metabolic process; skeletal muscle tissue regeneration; response to drug; aging; glycolysis; gluconeogenesis; carbohydrate metabolic process | |
| ENOX1 | transport; electron transport chain; rhythmic process | |
| ENPEP | glomerulus development; angiogenesis; angiotensin catabolic process in blood; regulation of systemic arterial blood pressure by renin-angiotensin; proteolysis; cell-cell signaling; metabolic process; cell proliferation; cell migration | |
| ENPP1 | 3'-phosphoadenosine 5'-phosphosulfate metabolic process; bone remodeling; negative regulation of insulin receptor signaling pathway; negative regulation of glucose import; phosphate-containing compound metabolic process; negative regulation of fat cell differentiation; immune response; riboflavin metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process; generation of precursor metabolites and energy; nucleoside triphosphate catabolic process; negative regulation of ossification; negative regulation of cell growth; regulation of bone mineralization; inorganic diphosphate transport; cellular phosphate ion homeostasis; sequestering of triglyceride; biomineral tissue development; negative regulation of protein autophosphorylation; cellular response to insulin stimulus; small molecule metabolic process; negative regulation of glycogen biosynthetic process | |
| ENPP2 | phosphate-containing compound metabolic process; phosphatidylcholine catabolic process; regulation of cell migration; lipid catabolic process; G-protein coupled receptor signaling pathway; immune response; chemotaxis; cellular component movement | |
| ENPP3 | inorganic diphosphate transport; phosphate-containing compound metabolic process; immune response; nucleoside triphosphate catabolic process | |
| ENPP5 | cell communication | |
| ENPP6 | choline metabolic process; lipid catabolic process | |
| ENPP7 | sphingolipid metabolic process; sphingomyelin metabolic process; glycosphingolipid metabolic process; negative regulation of DNA replication; negative regulation of cell proliferation; small molecule metabolic process | |
| ENTHD1 | - | |
| ENTHD2 | - | |
| ENTPD2 | platelet activation; purine ribonucleoside diphosphate catabolic process; G-protein coupled receptor signaling pathway | |
| ENTPD4 | UDP catabolic process | |
| ENTPD5 | ATP metabolic process; 'de novo' posttranslational protein folding; glycolysis; protein N-linked glycosylation; metabolic process; cell proliferation; regulation of phosphatidylinositol 3-kinase cascade; cell growth | |
| ENTPD6 | response to magnesium ion; response to calcium ion | |
| ENTPD7 | - | |
| ENTPD8 | nucleoside diphosphate biosynthetic process; nucleoside monophosphate biosynthetic process | |
| EOGT | - | |
| EOMES | blastocyst development; mesodermal to mesenchymal transition involved in gastrulation; cell differentiation involved in embryonic placenta development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of cell differentiation; cerebral cortex neuron differentiation; brain development; multicellular organismal development; CD8-positive, alpha-beta T cell differentiation involved in immune response; trophectodermal cell differentiation; mesoderm formation; endoderm formation; endodermal cell fate specification | |
| EP300 | positive regulation of sequence-specific DNA binding transcription factor activity; response to ethanol; positive regulation of translation; positive regulation of axon extension; positive regulation of cell size; innate immune response; positive regulation of proteolysis; positive regulation of transcription from RNA polymerase II promoter; digestive tract development; positive regulation of protein secretion; negative regulation of transcription from RNA polymerase II promoter; response to glucocorticoid stimulus; response to calcium ion; regulation of angiotensin metabolic process; positive regulation of sarcomere organization; regulation of androgen receptor signaling pathway; protein-DNA complex assembly; cellular response to hydrogen peroxide; response to fatty acid; nervous system development; N-terminal peptidyl-lysine acetylation; histone acetylation; response to organic cyclic compound; positive regulation of glycoprotein biosynthetic process; organ morphogenesis; response to glucose stimulus; skele | |
| EP400 | regulation of transcription, DNA-dependent; chromatin modification; histone H4 acetylation; histone H2A acetylation | |
| EPAS1 | multicellular organismal development; angiogenesis; embryonic placenta development; blood vessel remodeling; regulation of heart rate; transcription from RNA polymerase II promoter; response to oxidative stress; mitochondrion organization; signal transduction; visual perception; response to hypoxia; myoblast cell fate commitment; cell maturation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; surfactant homeostasis; norepinephrine metabolic process; lung development; erythrocyte differentiation; cell differentiation; hemopoiesis | |
| EPB41 | blood circulation; actin cytoskeleton organization; cortical actin cytoskeleton organization; positive regulation of protein binding | |
| EPB41L1 | synaptic transmission; cortical actin cytoskeleton organization | |
| EPB41L3 | cortical actin cytoskeleton organization | |
| EPB41L4A | - | |
| EPB41L4B | - | |
| EPB41L5 | - | |
| EPB42 | erythrocyte maturation; peptide cross-linking; regulation of cell shape | |
| EPC1 | histone H2A acetylation; negative regulation of gene expression, epigenetic; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; chromatin modification; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of growth; histone H4 acetylation; positive regulation of transcription, DNA-dependent | |
| EPDR1 | cell-matrix adhesion | |
| EPG5 | autophagy | |
| EPHA1 | protein autophosphorylation; positive regulation of stress fiber assembly; positive regulation of angiogenesis; substrate adhesion-dependent cell spreading; activation of Rho GTPase activity; regulation of Rac GTPase activity; negative regulation of cell migration; positive regulation of cell migration; positive regulation of cell proliferation; cell surface receptor signaling pathway; cell adhesion; negative regulation of protein kinase activity; positive regulation of cell-matrix adhesion; peptidyl-tyrosine phosphorylation | |
| EPHA10 | - | |
| EPHA2 | activation of Rac GTPase activity; cell chemotaxis; mammary gland epithelial cell proliferation; regulation of cell adhesion mediated by integrin; tail morphogenesis; protein kinase B signaling cascade; regulation of blood vessel endothelial cell migration; regulation of angiogenesis; bone remodeling; ephrin receptor signaling pathway; axial mesoderm formation; negative regulation of protein kinase B signaling cascade; notochord cell development; osteoclast differentiation; keratinocyte differentiation; neuron differentiation; neural tube development; notochord formation; regulation of lamellipodium assembly; multicellular organismal development; cell adhesion; apoptotic process; osteoblast differentiation; vasculogenesis; skeletal system development; blood vessel development; lens fiber cell morphogenesis; branching involved in mammary gland duct morphogenesis; regulation of ERK1 and ERK2 cascade; response to growth factor stimulus; positive regulation of establishment of protein localization in plasma membr | |
| EPHA3 | cellular response to retinoic acid; fever generation; apoptotic process; cell adhesion; regulation of epithelial to mesenchymal transition; positive regulation of neuron projection development; cell migration; regulation of Rho GTPase activity; response to lipopolysaccharide; regulation of actin cytoskeleton organization; ephrin receptor signaling pathway; regulation of focal adhesion assembly; regulation of microtubule cytoskeleton organization; response to cytokine stimulus; fasciculation of motor neuron axon; fasciculation of sensory neuron axon | |
| EPHA5 | regulation of Rac GTPase activity; nervous system development; axon guidance; hippocampus development; positive regulation of CREB transcription factor activity; regulation of actin cytoskeleton organization; ephrin receptor signaling pathway; neuron development; dendritic spine morphogenesis; regulation of insulin secretion involved in cellular response to glucose stimulus; cAMP-mediated signaling | |
| EPHA7 | regulation of peptidyl-tyrosine phosphorylation; multicellular organismal development; axon guidance; brain development; phosphorylation; regulation of cell-cell adhesion; retinal ganglion cell axon guidance; regulation of protein autophosphorylation; regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of neuron apoptosis; ephrin receptor signaling pathway; branching morphogenesis of a nerve; negative chemotaxis; regulation of ERK1 and ERK2 cascade | |
| EPHA8 | positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of MAPK cascade; substrate-dependent cell migration; multicellular organismal development; nervous system development; axon guidance; neuron remodeling; regulation of cell adhesion; neuron projection development; regulation of cell adhesion mediated by integrin; ephrin receptor signaling pathway; protein autophosphorylation | |
| EPHB2 | ephrin receptor signaling pathway; commissural neuron axon guidance; dendritic spine morphogenesis; dendritic spine development; palate development; positive regulation of synapse assembly; regulation of body fluid levels; inner ear morphogenesis; corpus callosum development; peptidyl-tyrosine phosphorylation; phosphorylation; axonal fasciculation; axon guidance; nervous system development; multicellular organismal development; protein phosphorylation; urogenital system development; angiogenesis | |
| EPHB3 | angiogenesis; regulation of Cdc42 GTPase activity; multicellular organismal development; nervous system development; axon guidance; axonal fasciculation; cell migration; central nervous system projection neuron axonogenesis; corpus callosum development; regulation of cell-cell adhesion; retinal ganglion cell axon guidance; regulation of Rac GTPase activity; substrate adhesion-dependent cell spreading; protein autophosphorylation; ephrin receptor signaling pathway; thymus development; digestive tract morphogenesis; regulation of axonogenesis; positive regulation of synapse assembly; palate development; dendritic spine development; signal transduction; urogenital system development; dendritic spine morphogenesis | |
| EPHB4 | ephrin receptor signaling pathway; cell adhesion; multicellular organismal development; protein autophosphorylation; heart morphogenesis; cell migration involved in sprouting angiogenesis; angiogenesis | |
| EPHB6 | ephrin receptor signaling pathway | |
| EPHX1 | aromatic compound catabolic process; response to organic cyclic compound; response to toxin | |
| EPHX2 | regulation of blood pressure; reactive oxygen species metabolic process; positive regulation of vasodilation; aromatic compound catabolic process; drug metabolic process; response to toxin; xenobiotic metabolic process; cellular calcium ion homeostasis; inflammatory response | |
| EPHX4 | - | |
| EPN3 | - | |
| EPOR | signal transduction; decidualization; cellular response to erythropoietin; embryo development; heart development; brain development; elevation of cytosolic calcium ion concentration | |
| EPRS | gene expression; protein complex assembly; prolyl-tRNA aminoacylation; glutamyl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| EPS15 | cell proliferation; clathrin coat assembly; epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; endocytic recycling; vesicle organization; protein transport | |
| EPS15L1 | negative regulation of epidermal growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; endocytosis | |
| EPS8 | signal transduction; epidermal growth factor receptor signaling pathway; cell proliferation | |
| EPS8L1 | - | |
| EPS8L2 | - | |
| EPS8L3 | - | |
| EPSTI1 | - | |
| EPX | hydrogen peroxide catabolic process; response to oxidative stress | |
| EPYC | female pregnancy | |
| EQTN | - | |
| ERAL1 | ribosome biogenesis; ribosomal small subunit assembly | |
| ERAP2 | antigen processing and presentation of endogenous peptide antigen via MHC class I; antigen processing and presentation of peptide antigen via MHC class I; proteolysis; regulation of blood pressure | |
| ERBB2 | positive regulation of transcription from RNA polymerase III promoter; positive regulation of protein phosphorylation; negative regulation of immature T cell proliferation in thymus; regulation of microtubule-based process; response to progesterone stimulus; positive regulation of Rho GTPase activity; mammary gland development; positive regulation of cell growth; signal transduction by phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase cascade; glial cell differentiation; cell proliferation; motor axon guidance; liver development; wound healing; regulation of transcription, DNA-dependent; protein phosphorylation; signal transduction; cell surface receptor signaling pathway; enzyme linked receptor protein signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; epidermal growth factor receptor signaling pathway; nervous system development; axon guidance; peripheral nervous system development; heart development; skeletal muscl | |
| ERBB2IP | basal protein localization; establishment or maintenance of epithelial cell apical/basal polarity; intermediate filament cytoskeleton organization; cell cycle; cell growth; integrin-mediated signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; cell adhesion | |
| ERBB3 | endocardial cushion development; tongue development; positive regulation of protein tyrosine kinase activity; mammary gland involution; neuron apoptosis; negative regulation of secretion; positive regulation of glucose import; response to drug; negative regulation of cell adhesion; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; axonogenesis; peripheral nervous system development; heart development; skeletal muscle tissue development; circadian rhythm; negative regulation of signal transduction; Schwann cell differentiation; phosphatidylinositol 3-kinase cascade; positive regulation of phosphatidylinositol 3-kinase cascade; cranial nerve development; cellular response to insulin stimulus; wound healing; regulation of cell proliferation; odontogenesis; negative regulation of neuron apoptosis | |
| ERBB4 | positive regulation of STAT protein import into nucleus; telencephalon development; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; multicellular organismal development; nervous system development; heart development; lactation; cell proliferation; positive regulation of cell proliferation; negative regulation of cell proliferation; embryonic pattern specification; cell migration; peptidyl-tyrosine phosphorylation; apoptotic process; central nervous system morphogenesis; olfactory bulb interneuron differentiation; regulation of cell migration; positive regulation of cell migration; positive regulation of synaptic transmission, GABAergic; response to progesterone stimulus; response to drug; positive regulation of tyrosine phosphorylation of Stat5 protein; response to hydrogen peroxide; negative regulation of apoptotic process; surfactant homeostasis; positive regulation of protein phosphorylation; positive regulation of ERK1 and ERK2 cascade; cardiac muscle tissue regenera | |
| ERC1 | positive regulation of anti-apoptosis; retrograde transport, endosome to Golgi; multicellular organismal development; I-kappaB phosphorylation; positive regulation of NF-kappaB transcription factor activity; regulation of transcription, DNA-dependent; protein transport | |
| ERCC1 | post-embryonic hemopoiesis; multicellular organism growth; negative regulation of apoptotic process; isotype switching; oogenesis; embryonic organ development; chromosome organization; negative regulation of telomere maintenance; response to X-ray; multicellular organismal aging; pyrimidine dimer repair by nucleotide-excision repair; response to sucrose stimulus; UV protection; response to abiotic stimulus; nucleotide-excision repair, DNA damage removal; male gonad development; cell proliferation; response to nutrient; spermatogenesis; germ cell development; response to oxidative stress; mitotic recombination; DNA recombination; double-strand break repair; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; syncytium formation; replicative cell aging; DNA repair | |
| ERCC2 | hair cell differentiation; multicellular organism growth; nucleotide-excision repair, DNA incision; central nervous system myelin formation; UV protection; bone mineralization; extracellular matrix organization; spinal cord development; viral reproduction; gene expression; post-embryonic development; embryonic cleavage; negative regulation of apoptotic process; transcription from RNA polymerase I promoter; erythrocyte maturation; positive regulation of DNA binding; skin development; interspecies interaction between organisms; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; hair follicle maturation; positive regulation of viral transcription; hemopoietic stem cell differentiation; aging; cell proliferation; cell cycle checkpoint; nucleotide-excision repair, DNA damage removal; response to hypoxia; in utero embryonic development; nucleobase-containing compound metabolic process; DNA repair; transcription-coupled nucleotide-excision repai | |
| ERCC3 | transcription elongation from RNA polymerase II promoter; mRNA capping; protein phosphorylation; transcription initiation from RNA polymerase I promoter; induction of apoptosis; response to oxidative stress; protein localization; response to UV; UV protection; gene expression; viral reproduction; nucleotide-excision repair, DNA incision; hair cell differentiation; interspecies interaction between organisms; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; cell cycle checkpoint; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA damage removal; response to hypoxia; ATP catabolic process; DNA topological change; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase I promoter; transcription elongation | |
| ERCC4 | nucleotide-excision repair, DNA incision; negative regulation of telomere maintenance; telomere maintenance via telomere shortening; UV protection; response to UV; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair; DNA repair; double-strand break repair via homologous recombination; telomere maintenance; nucleotide-excision repair, DNA damage removal; resolution of meiotic recombination intermediates; meiotic mismatch repair; transcription-coupled nucleotide-excision repair | |
| ERCC6 | transcription-coupled nucleotide-excision repair; response to toxin; response to UV-B; response to X-ray; photoreceptor cell maintenance; DNA repair; response to superoxide; activation of JUN kinase activity; response to oxidative stress; nucleotide-excision repair; response to UV; base-excision repair; response to gamma radiation; regulation of transcription elongation, DNA-dependent; pyrimidine dimer repair; positive regulation of transcription elongation, DNA-dependent; activation of JNKK activity; transcription from RNA polymerase II promoter; DNA damage response, signal transduction resulting in induction of apoptosis | |
| ERCC6L | M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cell division | |
| ERCC6L2 | DNA repair | |
| ERCC8 | nucleotide-excision repair; DNA repair; response to oxidative stress; protein autoubiquitination; protein polyubiquitination; response to DNA damage stimulus; transcription-coupled nucleotide-excision repair; response to UV; positive regulation of DNA repair; proteasomal ubiquitin-dependent protein catabolic process; response to X-ray | |
| ERGIC1 | ER to Golgi vesicle-mediated transport; vesicle-mediated transport | |
| ERI2 | - | |
| ERICH3 | - | |
| ERICH6 | - | |
| ERLEC1 | ER-associated protein catabolic process | |
| ERLIN2 | ER-associated protein catabolic process | |
| ERMAP | - | |
| ERMP1 | ovarian follicle development; proteolysis | |
| ERO1A | oxidation-reduction process; chaperone mediated protein folding requiring cofactor; protein folding; protein modification process; protein thiol-disulfide exchange; transport; electron transport chain; response to temperature stimulus; brown fat cell differentiation; endoplasmic reticulum unfolded protein response | |
| ERO1B | electron transport chain; protein folding; protein thiol-disulfide exchange; transport; oxidation-reduction process | |
| ERP27 | - | |
| ERP44 | response to stress; protein folding; glycoprotein metabolic process; cell redox homeostasis; response to unfolded protein | |
| ESCO1 | regulation of DNA replication; cell cycle; post-translational protein acetylation | |
| ESD | metabolic process | |
| ESF1 | regulation of transcription, DNA-dependent | |
| ESPL1 | proteolysis; meiotic spindle organization; mitotic sister chromatid segregation; apoptotic process; cytokinesis; establishment of mitotic spindle localization; negative regulation of sister chromatid cohesion; homologous chromosome segregation; metabolic process; positive regulation of mitotic metaphase/anaphase transition; chromosome segregation | |
| ESR2 | negative regulation of transcription from RNA polymerase II promoter; ovarian follicle development; neuron migration; regulation of transcription, DNA-dependent; signal transduction; cell-cell signaling; brain development; negative regulation of signal transduction; gene expression; negative regulation of cell growth; intracellular estrogen receptor signaling pathway; intracellular receptor mediated signaling pathway; positive regulation of apoptotic process; steroid hormone mediated signaling pathway; negative regulation of epithelial cell proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; uterus development; vagina development; prostate gland epithelium morphogenesis; epithelial cell maturation involved in prostate gland development; negative regulation of androgen receptor signaling pathway | |
| ESRP2 | regulation of RNA splicing; mRNA processing | |
| ESRRG | gene expression; positive regulation of transcription, DNA-dependent | |
| ESX1 | negative regulation of transcription, DNA-dependent; blood vessel development; regulation of transcription from RNA polymerase II promoter; labyrinthine layer blood vessel development; labyrinthine layer morphogenesis; regulation of cell cycle | |
| ESYT1 | - | |
| ESYT2 | - | |
| ESYT3 | - | |
| ETAA1 | - | |
| ETFB | transport; respiratory electron transport chain; small molecule metabolic process | |
| ETFDH | transport; response to oxidative stress; electron transport chain; respiratory electron transport chain; fatty acid beta-oxidation using acyl-CoA dehydrogenase; small molecule metabolic process | |
| ETHE1 | sulfur amino acid metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; sulfur amino acid catabolic process; sulfide oxidation, using sulfide:quinone oxidoreductase | |
| ETS1 | response to laminar fluid shear stress; positive regulation of erythrocyte differentiation; positive regulation of angiogenesis; cellular response to hydrogen peroxide; PML body organization; pituitary gland development; positive regulation of cell migration; response to estradiol stimulus; negative regulation of cell cycle; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to antibiotic; cell motility; positive regulation of cellular component movement; angiogenesis involved in wound healing; estrous cycle phase; regulation of extracellular matrix disassembly; response to mechanical stimulus; response to wounding; negative regulation of cell proliferation; positive regulation of cell proliferation; female pregnancy; immune response; induction of apoptosis; anti-apoptosis; transcription from RNA polymerase II promoter; response to hypoxia; response to interleukin-1; hypothalamus development | |
| ETV4 | regulation of transcription, DNA-dependent; motor axon guidance; negative regulation of mammary gland epithelial cell proliferation; positive regulation of transcription, DNA-dependent; stem cell differentiation; regulation of branching involved in mammary gland duct morphogenesis | |
| ETV5 | regulation of transcription, DNA-dependent; cellular response to oxidative stress; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; male germ-line stem cell division; positive regulation of glial cell proliferation; regulation of branching involved in mammary gland duct morphogenesis | |
| ETV6 | regulation of transcription, DNA-dependent | |
| ETV7 | organ morphogenesis; transcription from RNA polymerase II promoter | |
| EVA1A | - | |
| EVA1C | - | |
| EVI2A | - | |
| EVI5 | cell cycle; multicellular organismal development; cell proliferation; cell division | |
| EVI5L | - | |
| EVL | protein homotetramerization; actin polymerization or depolymerization; organ morphogenesis; actin filament organization; axon guidance; nervous system development; cell surface receptor signaling pathway | |
| EVPL | keratinization; keratinocyte differentiation; peptide cross-linking; epidermis development | |
| EVX1 | regulation of transcription, DNA-dependent; multicellular organismal development; embryo development ending in birth or egg hatching; regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; positive regulation of transcription from RNA polymerase II promoter | |
| EVX2 | limb morphogenesis; multicellular organismal development | |
| EXD1 | nucleobase-containing compound metabolic process | |
| EXD2 | nucleobase-containing compound metabolic process | |
| EXO1 | DNA repair; isotype switching; humoral immune response mediated by circulating immunoglobulin; somatic hypermutation of immunoglobulin genes; mismatch repair; DNA recombination; meiosis | |
| EXOC2 | exocytosis; protein transport | |
| EXOC3L1 | exocytosis; peptide hormone secretion | |
| EXOC4 | membrane biogenesis; protein targeting to membrane; vesicle docking involved in exocytosis; synaptic transmission; establishment of cell polarity; oligodendrocyte differentiation; positive regulation of calcium-mediated signaling; regulation of protein transport; Golgi to transport vesicle transport | |
| EXOC6 | vesicle docking involved in exocytosis; protein transport | |
| EXOC7 | exocytosis; protein transport | |
| EXOC8 | protein transport; exocytosis | |
| EXOSC10 | nuclear polyadenylation-dependent rRNA catabolic process; maturation of 5.8S rRNA; histone mRNA catabolic process; nuclear retention of unspliced pre-mRNA at the site of transcription; nuclear mRNA surveillance; CUT catabolic process; cellular metabolic process; RNA processing; nucleobase-containing compound metabolic process; nuclear-transcribed mRNA catabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | |
| EXPH5 | positive regulation of exocytosis; positive regulation of protein secretion; intracellular protein transport; multivesicular body sorting pathway | |
| EXT1 | glycosaminoglycan biosynthetic process; cellular polysaccharide biosynthetic process; skeletal system development; olfactory bulb development; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparan sulfate proteoglycan biosynthetic process; mesoderm development; endoderm development; brain development; axon guidance; gastrulation; signal transduction; ossification | |
| EXTL1 | skeletal system development | |
| EXTL3 | activation of signaling protein activity involved in unfolded protein response; positive regulation of cell growth; endoplasmic reticulum unfolded protein response | |
| EYA1 | response to ionizing radiation; positive regulation of DNA repair; peptidyl-tyrosine dephosphorylation; protein sumoylation; histone dephosphorylation; chromatin modification; anatomical structure morphogenesis; sensory perception of sound; multicellular organismal development; regulation of transcription, DNA-dependent; double-strand break repair | |
| EYA2 | DNA repair; regulation of transcription, DNA-dependent; apoptotic process; histone dephosphorylation; chromatin modification; multicellular organismal development; striated muscle tissue development; mesodermal cell fate specification; peptidyl-tyrosine dephosphorylation | |
| EYA3 | double-strand break repair; regulation of transcription, DNA-dependent; visual perception; anatomical structure morphogenesis; response to ionizing radiation; chromatin modification; histone dephosphorylation; peptidyl-tyrosine dephosphorylation; positive regulation of DNA repair; multicellular organismal development | |
| EYA4 | DNA repair; chromatin modification; anatomical structure morphogenesis; visual perception; multicellular organismal development; regulation of transcription, DNA-dependent | |
| EYS | visual perception; response to stimulus | |
| EZH1 | peptidyl-lysine methylation; chromatin modification; anatomical structure morphogenesis; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| EZR | actin filament bundle assembly; establishment or maintenance of apical/basal cell polarity; epithelial cell differentiation; membrane to membrane docking; regulation of cell shape; axon guidance; leukocyte cell-cell adhesion; cytoskeletal anchoring at plasma membrane | |
| F10 | positive regulation of protein kinase B signaling cascade; proteolysis; cellular protein metabolic process; post-translational protein modification; positive regulation of cell migration; peptidyl-glutamic acid carboxylation; blood coagulation, extrinsic pathway; blood coagulation, intrinsic pathway; blood coagulation | |
| F11 | proteolysis; blood coagulation; blood coagulation, intrinsic pathway; regulation of blood coagulation; plasminogen activation; positive regulation of fibrinolysis | |
| F12 | positive regulation of fibrinolysis; Factor XII activation; proteolysis; blood coagulation; blood coagulation, intrinsic pathway; positive regulation of plasminogen activation; protein processing; protein autoprocessing; positive regulation of blood coagulation; zymogen activation; response to misfolded protein; plasma kallikrein-kinin cascade; innate immune response | |
| F13A1 | platelet degranulation; platelet activation; peptide cross-linking; blood coagulation | |
| F13B | blood coagulation | |
| F2 | peptidyl-glutamic acid carboxylation; platelet activation; regulation of blood coagulation; positive regulation of phosphatidylinositol 3-kinase cascade; negative regulation of platelet activation; response to wounding; positive regulation of cell proliferation; regulation of cell shape; positive regulation of blood coagulation; positive regulation of cell growth; positive regulation of collagen biosynthetic process; fibrinolysis; post-translational protein modification; cellular protein metabolic process; negative regulation of proteolysis; negative regulation of astrocyte differentiation; leukocyte migration; positive regulation of release of sequestered calcium ion into cytosol; cytosolic calcium ion homeostasis; negative regulation of fibrinolysis; positive regulation of reactive oxygen species metabolic process; blood coagulation, intrinsic pathway; blood coagulation; multicellular organismal development; cell surface receptor signaling pathway; acute-phase response; proteolysis; positive regulation of p | |
| F2R | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to wounding; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-8 secretion; positive regulation of collagen biosynthetic process; regulation of interleukin-1 beta production; response to lipopolysaccharide; positive regulation of cell migration; positive regulation of interleukin-6 secretion; positive regulation of blood coagulation; regulation of blood coagulation; platelet activation; death; positive regulation of phosphatidylinositol 3-kinase cascade; anatomical structure morphogenesis; positive regulation of Rho protein signal transduction; positive regulation of MAPK cascade; negative regulation of neuron apoptosis; thrombin receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; platelet dense granule organization; regulation of sensory perception of pain; positive regulation of calcium ion transport; elevation of cytosolic calcium ion concentra | |
| F2RL1 | interleukin-1 beta secretion; positive regulation of JNK cascade; negative regulation of JNK cascade; regulation of JNK cascade; positive regulation of transcription from RNA polymerase II promoter; positive regulation of vasodilation; innate immune response; positive regulation of eosinophil degranulation; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of I-kappaB kinase/NF-kappaB cascade; neutrophil activation; chemokine (C-C motif) ligand 2 secretion; positive regulation of Rho protein signal transduction; negative regulation of toll-like receptor 3 signaling pathway; positive regulation of toll-like receptor 3 signaling pathway; positive regulation of toll-like receptor 4 signaling pathway; leukocyte migration; positive regulation of chemotaxis; positive regulation of positive chemotaxis; defense response to virus; positive regulation of phagocytosis, engulfment; establishment of endothelial barrier; positive regulation of ERK1 and ERK2 cascade; leukocyte proliferation; positive regu | |
| F2RL2 | thrombin receptor signaling pathway; platelet activation; response to wounding; blood coagulation | |
| F2RL3 | signal transduction; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; blood coagulation; response to wounding; platelet activation; positive regulation of release of sequestered calcium ion into cytosol; platelet dense granule organization; thrombin receptor signaling pathway | |
| F3 | positive regulation of platelet-derived growth factor receptor signaling pathway; response to mechanical stimulus; response to wounding; response to temperature stimulus; blood coagulation, extrinsic pathway; blood coagulation; aging; activation of cysteine-type endopeptidase activity involved in apoptotic process; anti-apoptosis; activation of blood coagulation via clotting cascade; activation of plasma proteins involved in acute inflammatory response; positive regulation of endothelial cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of cell migration; response to estradiol stimulus; response to lipopolysaccharide; cellular response to hydrogen peroxide; response to low-density lipoprotein particle stimulus; positive regulation of protein kinase B signaling cascade; positive regulation of positive chemotaxis; positive regulation of angiogenesis; response to fluid shear stress | |
| F5 | platelet activation; blood circulation; blood coagulation; cell adhesion; platelet degranulation | |
| F7 | blood coagulation, extrinsic pathway; blood coagulation; anti-apoptosis; proteolysis; positive regulation of leukocyte chemotaxis; response to hormone stimulus; positive regulation of platelet-derived growth factor receptor signaling pathway; response to organic cyclic compound; peptidyl-glutamic acid carboxylation; positive regulation of blood coagulation; positive regulation of cell migration; organ regeneration; response to nutrient levels; response to vitamin K; response to estrogen stimulus; post-translational protein modification; cellular protein metabolic process; positive regulation of positive chemotaxis; positive regulation of protein kinase B signaling cascade; response to growth hormone stimulus; circadian rhythm | |
| F8 | platelet degranulation; acute-phase response; cell adhesion; blood coagulation; blood coagulation, intrinsic pathway; platelet activation | |
| F9 | blood coagulation, intrinsic pathway; blood coagulation, extrinsic pathway; peptidyl-glutamic acid carboxylation; post-translational protein modification; cellular protein metabolic process; proteolysis; blood coagulation | |
| FAAH2 | - | |
| FAAP100 | DNA repair | |
| FABP1 | small molecule metabolic process; cellular lipid metabolic process; positive regulation of fatty acid beta-oxidation; organ morphogenesis; positive regulation of cell proliferation; intestinal absorption; positive regulation of hydrolase activity | |
| FABP3 | fatty acid metabolic process; phosphatidylcholine biosynthetic process; negative regulation of cell proliferation; response to insulin stimulus; response to drug; response to fatty acid | |
| FABP4 | cytokine production; brown fat cell differentiation; cellular response to lithium ion; negative regulation of protein kinase activity; lipid metabolic process; triglyceride catabolic process; cholesterol homeostasis; small molecule metabolic process; negative regulation of transcription, DNA-dependent; positive regulation of inflammatory response; white fat cell differentiation | |
| FABP6 | bile acid and bile salt transport; negative regulation of cell proliferation; bile acid metabolic process; lipid metabolic process; small molecule metabolic process | |
| FADD | cellular response to mechanical stimulus; positive regulation of apoptotic process; positive regulation of extrinsic apoptotic signaling pathway; extrinsic apoptotic signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; interspecies interaction between organisms; innate immune response; induction of apoptosis by extracellular signals; induction of apoptosis via death domain receptors; activation of pro-apoptotic gene products; positive regulation of interleukin-8 production; positive regulation of transcription from RNA polymerase II promoter; defense response to virus; positive regulation of type I interferon-mediated signaling pathway; necrotic cell death; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; positive regulation of tumor necrosis factor production | |
| FAF2 | response to unfolded protein | |
| FAH | tyrosine catabolic process; aromatic amino acid family metabolic process; cellular nitrogen compound metabolic process; L-phenylalanine catabolic process; arginine catabolic process; small molecule metabolic process | |
| FAM102B | - | |
| FAM104B | - | |
| FAM107B | - | |
| FAM109A | endosome organization; retrograde transport, endosome to Golgi; receptor recycling | |
| FAM110A | - | |
| FAM110B | - | |
| FAM110C | - | |
| FAM111A | - | |
| FAM111B | - | |
| FAM114A1 | - | |
| FAM117B | - | |
| FAM118B | - | |
| FAM120A | - | |
| FAM120AOS | - | |
| FAM120B | cell differentiation; regulation of transcription, DNA-dependent | |
| FAM120C | - | |
| FAM122B | - | |
| FAM122C | - | |
| FAM124A | - | |
| FAM124B | - | |
| FAM126A | signal transduction | |
| FAM129A | response to stress; response to endoplasmic reticulum stress; positive regulation of translation; positive regulation of protein phosphorylation; negative regulation of protein phosphorylation | |
| FAM129B | negative regulation of apoptotic process | |
| FAM131A | - | |
| FAM131B | - | |
| FAM134B | sensory perception of pain | |
| FAM134C | - | |
| FAM135A | - | |
| FAM135B | - | |
| FAM13A | signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction | |
| FAM13B | regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction | |
| FAM13C | - | |
| FAM149A | - | |
| FAM151A | - | |
| FAM155A | - | |
| FAM160A2 | protein transport; endosome to lysosome transport; endosome organization; lysosome organization; early endosome to late endosome transport | |
| FAM160B1 | - | |
| FAM161A | visual perception; response to stimulus | |
| FAM161B | - | |
| FAM162B | - | |
| FAM163A | - | |
| FAM166A | - | |
| FAM167A | - | |
| FAM167B | - | |
| FAM170A | - | |
| FAM171A1 | - | |
| FAM171B | - | |
| FAM172A | - | |
| FAM174A | - | |
| FAM175B | - | |
| FAM179B | - | |
| FAM180A | - | |
| FAM181A | - | |
| FAM184A | - | |
| FAM186B | - | |
| FAM188A | apoptotic process | |
| FAM189B | - | |
| FAM193A | - | |
| FAM196A | - | |
| FAM198B | - | |
| FAM199X | - | |
| FAM19A3 | - | |
| FAM19A4 | - | |
| FAM208A | - | |
| FAM208B | - | |
| FAM209B | - | |
| FAM20A | - | |
| FAM210A | - | |
| FAM213A | regulation of osteoclast differentiation; oxidation-reduction process | |
| FAM217A | - | |
| FAM217B | - | |
| FAM219B | - | |
| FAM228A | - | |
| FAM229B | - | |
| FAM234A | - | |
| FAM234B | - | |
| FAM3B | apoptotic process; insulin secretion | |
| FAM43A | - | |
| FAM45A | - | |
| FAM46A | - | |
| FAM46C | - | |
| FAM46D | - | |
| FAM47A | - | |
| FAM49A | - | |
| FAM49B | - | |
| FAM50A | spermatogenesis | |
| FAM53A | - | |
| FAM53B | - | |
| FAM57B | - | |
| FAM63A | - | |
| FAM63B | - | |
| FAM65A | - | |
| FAM65C | - | |
| FAM71A | - | |
| FAM71B | - | |
| FAM71C | - | |
| FAM71F1 | - | |
| FAM73A | - | |
| FAM73B | - | |
| FAM78A | - | |
| FAM83A | - | |
| FAM83B | - | |
| FAM83E | - | |
| FAM83F | - | |
| FAM83G | - | |
| FAM83H | biomineral tissue development | |
| FAM84A | - | |
| FAM84B | - | |
| FAM8A1 | - | |
| FAM91A1 | - | |
| FAN1 | nucleotide-excision repair; double-strand break repair via homologous recombination; nucleotide-excision repair, DNA incision; DNA repair | |
| FANCA | DNA repair; protein complex assembly; male meiosis; male gonad development; female gonad development; regulation of cell proliferation | |
| FANCB | DNA repair | |
| FANCC | DNA repair; removal of superoxide radicals; germ cell development; protein complex assembly; myeloid cell homeostasis; nucleotide-excision repair | |
| FANCD2 | gamete generation; synapsis; cell cycle; DNA repair; response to gamma radiation | |
| FANCI | DNA repair; cell cycle | |
| FANCL | protein ubiquitination; DNA repair | |
| FANCM | DNA repair; replication fork processing; resolution of meiotic recombination intermediates | |
| FAP | proteolysis; metabolic process; negative regulation of extracellular matrix disassembly; endothelial cell migration; regulation of fibrinolysis | |
| FAR1 | small molecule metabolic process; cellular lipid metabolic process; wax biosynthetic process; lipid biosynthetic process; ether lipid biosynthetic process | |
| FARP1 | regulation of Rho protein signal transduction; negative regulation of phosphatase activity | |
| FARP2 | axon guidance; regulation of Rho protein signal transduction; neuron remodeling; Rac protein signal transduction | |
| FARS2 | tRNA processing; tRNA aminoacylation; tRNA aminoacylation for protein translation; phenylalanyl-tRNA aminoacylation; gene expression | |
| FARSA | tRNA aminoacylation for protein translation; phenylalanyl-tRNA aminoacylation; gene expression | |
| FASN | fatty acid biosynthetic process; pantothenate metabolic process; triglyceride biosynthetic process; positive regulation of cellular metabolic process; vitamin metabolic process; long-chain fatty-acyl-CoA biosynthetic process; fatty acid metabolic process; energy reserve metabolic process; water-soluble vitamin metabolic process; small molecule metabolic process; cellular lipid metabolic process | |
| FASTK | protein phosphorylation; apoptotic process; induction of apoptosis by extracellular signals; regulation of RNA splicing | |
| FASTKD1 | cellular respiration | |
| FASTKD2 | cellular respiration | |
| FASTKD5 | cellular respiration | |
| FAT2 | cell adhesion; homophilic cell adhesion; epithelial cell migration | |
| FAT4 | cell adhesion; homophilic cell adhesion | |
| FATE1 | - | |
| FAXDC2 | - | |
| FBLN1 | extracellular matrix organization; embryo implantation; interspecies interaction between organisms | |
| FBLN5 | protein localization at cell surface; elastic fiber assembly; extracellular matrix organization; regulation of removal of superoxide radicals; cell-matrix adhesion; cell adhesion | |
| FBLN7 | cell adhesion | |
| FBN1 | skeletal system development; heart development; negative regulation of BMP signaling pathway by extracellular sequestering of BMP; negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta | |
| FBN2 | embryonic limb morphogenesis; bone trabecula formation; positive regulation of osteoblast differentiation; negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta; positive regulation of bone mineralization; anatomical structure morphogenesis | |
| FBN3 | - | |
| FBXL13 | - | |
| FBXL16 | - | |
| FBXL17 | - | |
| FBXL18 | - | |
| FBXL2 | protein modification process; protein ubiquitination; proteolysis; interspecies interaction between organisms | |
| FBXL3 | protein ubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; rhythmic process; regulation of circadian rhythm | |
| FBXO11 | sensory perception of sound; protein ubiquitination; ubiquitin-dependent protein catabolic process; protein modification process; peptidyl-arginine N-methylation | |
| FBXO16 | - | |
| FBXO18 | - | |
| FBXO22 | protein ubiquitination; protein polyubiquitination; protein modification process; ubiquitin-dependent protein catabolic process; regulation of myotube differentiation; nucleocytoplasmic transport; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; cellular response to starvation | |
| FBXO24 | protein ubiquitination | |
| FBXO3 | protein ubiquitination; proteolysis | |
| FBXO30 | - | |
| FBXO31 | response to DNA damage stimulus; cell cycle; cyclin catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; mitotic cell cycle G1/S transition DNA damage checkpoint | |
| FBXO32 | muscle atrophy | |
| FBXO33 | - | |
| FBXO38 | - | |
| FBXO40 | muscle cell differentiation | |
| FBXO42 | - | |
| FBXO43 | meiosis | |
| FBXO44 | protein catabolic process | |
| FBXO47 | - | |
| FBXO48 | - | |
| FBXO5 | regulation of meiosis; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of transcription involved in G1/S phase of mitotic cell cycle; inhibition of mitotic anaphase-promoting complex activity; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell division; M phase of mitotic cell cycle; mitotic metaphase; mitotic cell cycle; oocyte maturation; G1/S transition of mitotic cell cycle; vesicle organization; microtubule polymerization; regulation of mitotic cell cycle; mitotic metaphase/anaphase transition; spindle assembly; spindle assembly involved in female meiosis I | |
| FBXO7 | cell death; protein ubiquitination; regulation of protein stability; ubiquitin-dependent protein catabolic process | |
| FBXO8 | ubiquitin-dependent protein catabolic process; regulation of ARF protein signal transduction | |
| FBXW12 | - | |
| FBXW2 | proteolysis; protein ubiquitination; protein modification process | |
| FBXW5 | centrosome duplication; proteasomal ubiquitin-dependent protein catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination | |
| FBXW7 | lipid homeostasis; regulation of lipid storage; negative regulation of hepatocyte proliferation; negative regulation of Notch signaling pathway; negative regulation of SREBP-mediated signaling pathway; positive regulation of epidermal growth factor-activated receptor activity; interspecies interaction between organisms; cellular response to UV; regulation of protein localization; negative regulation of DNA endoreduplication; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; negative regulation of triglyceride biosynthetic process; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; sister chromatid cohesion; response to DNA damage stimulus; vasculature development; protein stabilization; positive regulation of ERK1 and ERK2 cascade | |
| FBXW8 | labyrinthine layer blood vessel development; spongiotrophoblast layer development | |
| FCAMR | - | |
| FCAR | immune response | |
| FCER1A | positive regulation of type I hypersensitivity; positive regulation of interleukin-3 biosynthetic process; serotonin secretion; cell surface receptor signaling pathway; leukotriene biosynthetic process; positive regulation of mast cell degranulation; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of peptidyl-tyrosine phosphorylation; activation of JUN kinase activity; positive regulation of calcium-mediated signaling | |
| FCGBP | - | |
| FCGR2A | - | |
| FCGR2B | immune response; signal transduction; interspecies interaction between organisms; regulation of immune response | |
| FCGRT | female pregnancy; antigen processing and presentation; immune response | |
| FCHO1 | - | |
| FCN3 | complement activation, lectin pathway; signal transduction | |
| FCRL3 | - | |
| FCRL4 | - | |
| FCRL5 | - | |
| FCRLA | cell differentiation | |
| FCRLB | - | |
| FDCSP | - | |
| FDFT1 | farnesyl diphosphate metabolic process; steroid biosynthetic process; cholesterol biosynthetic process; isoprenoid biosynthetic process; cellular lipid metabolic process; small molecule metabolic process | |
| FDPS | cholesterol biosynthetic process; isoprenoid biosynthetic process; small molecule metabolic process; interspecies interaction between organisms | |
| FDX1 | electron transport chain; generation of precursor metabolites and energy; transport; regulation of catalytic activity; adrenal gland development; response to gonadotropin stimulus; cellular response to leptin stimulus; cellular response to epinephrine stimulus; cellular response to organic cyclic compound; NADPH oxidation; positive regulation of oxidoreductase activity | |
| FDX1L | electron transport chain; transport | |
| FDXR | steroid biosynthetic process; NADPH oxidation; oxidation-reduction process; electron transport chain; cholesterol metabolic process; transport; generation of precursor metabolites and energy | |
| FECH | protoporphyrinogen IX metabolic process; generation of precursor metabolites and energy; porphyrin-containing compound metabolic process; heme biosynthetic process; response to light stimulus; small molecule metabolic process | |
| FEM1B | protein ubiquitination; regulation of DNA damage checkpoint; induction of apoptosis; regulation of apoptotic process; regulation of ubiquitin-protein ligase activity; branching involved in prostate gland morphogenesis; epithelial cell maturation involved in prostate gland development | |
| FEM1C | - | |
| FER | positive regulation of NF-kappaB transcription factor activity; platelet-derived growth factor receptor signaling pathway; protein autophosphorylation; regulation of epidermal growth factor receptor signaling pathway; intracellular signal transduction; positive regulation of actin filament polymerization; negative regulation of mast cell activation involved in immune response; microtubule cytoskeleton organization; protein phosphorylation; chemotaxis; cell adhesion; positive regulation of cell proliferation; regulation of lamellipodium assembly; peptidyl-tyrosine phosphorylation; positive regulation of cell migration | |
| FER1L6 | - | |
| FERMT1 | cell adhesion; keratinocyte proliferation; keratinocyte migration; establishment of epithelial cell polarity | |
| FERMT2 | cell junction assembly; actin cytoskeleton organization; regulation of cell shape; cell adhesion | |
| FETUB | - | |
| FEZF1 | negative regulation of cell proliferation; multicellular organismal development; nervous system development; axon guidance; positive regulation of neuron differentiation; telencephalon development; olfactory bulb development; forebrain anterior/posterior pattern specification; cell differentiation; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; neuron migration | |
| FEZF2 | negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter; multicellular organismal development; nervous system development; axon guidance; axonal fasciculation; locomotory behavior; dendrite development; telencephalon development; dentate gyrus development; forebrain anterior/posterior pattern specification; cell differentiation; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent | |
| FFAR2 | G-protein coupled receptor signaling pathway | |
| FFAR4 | - | |
| FGA | protein polymerization; response to calcium ion; platelet activation; blood coagulation; signal transduction; platelet degranulation | |
| FGD1 | regulation of small GTPase mediated signal transduction; multicellular organismal development; nerve growth factor receptor signaling pathway; regulation of cell shape; induction of apoptosis by extracellular signals; filopodium assembly; regulation of Cdc42 GTPase activity; regulation of Rho protein signal transduction; actin cytoskeleton organization; organ morphogenesis; small GTPase mediated signal transduction; signal transduction; cytoskeleton organization; apoptotic process | |
| FGD3 | small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; apoptotic process; cytoskeleton organization; regulation of cell shape; induction of apoptosis by extracellular signals; actin cytoskeleton organization; regulation of Rho protein signal transduction; regulation of Cdc42 GTPase activity; filopodium assembly | |
| FGD6 | cytoskeleton organization; regulation of cell shape; actin cytoskeleton organization; regulation of Rho protein signal transduction; regulation of Cdc42 GTPase activity; filopodium assembly | |
| FGF13 | MAPK cascade; positive regulation of protein phosphorylation; signal transduction; cell-cell signaling; nervous system development | |
| FGF17 | nervous system development; signal transduction; cell-cell signaling; multicellular organismal development; positive regulation of cell proliferation; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway | |
| FGF18 | endochondral ossification; intramembranous ossification; chondrocyte development; signal transduction; cell-cell signaling; positive regulation of cell proliferation; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; anatomical structure morphogenesis; lung development; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of chondrocyte differentiation; positive regulation of ERK1 and ERK2 cascade; angiogenesis; ossification | |
| FGF3 | otic vesicle formation; organ induction; signal transduction; cell-cell signaling; multicellular organismal development; positive regulation of cell proliferation; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; anatomical structure morphogenesis; cell differentiation; tail morphogenesis; thymus development; semicircular canal morphogenesis; positive regulation of cell division; negative regulation of cardiac muscle tissue development | |
| FGF4 | positive regulation of cell proliferation; cartilage condensation; signal transduction; cell-cell signaling; multicellular organismal development; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; mesenchymal cell proliferation; positive regulation of gene expression; stem cell maintenance; embryonic hindlimb morphogenesis; odontogenesis of dentin-containing tooth; negative regulation of apoptotic process; positive regulation of ERK1 and ERK2 cascade; chondroblast differentiation; apoptosis involved in morphogenesis; cranial suture morphogenesis; positive regulation of cell division; positive regulation of transcription from RNA polymerase II promoter | |
| FGF5 | fibroblast growth factor receptor signaling pathway; cell-cell signaling; nervous system development; cell proliferation; positive regulation of cell proliferation; positive regulation of cell division; signal transduction involved in regulation of gene expression; glial cell differentiation; insulin receptor signaling pathway | |
| FGF7 | wound healing; lung development; hair follicle morphogenesis; actin cytoskeleton reorganization; protein localization at cell surface; fibroblast growth factor receptor signaling pathway; positive regulation of epithelial cell proliferation; ovarian follicle development; positive regulation of keratinocyte proliferation; mesenchymal cell proliferation; response to wounding; phospholipid biosynthetic process; epidermis development; phosphatidylcholine biosynthetic process; signal transduction; positive regulation of cell proliferation; insulin receptor signaling pathway; secretion by lung epithelial cell involved in lung growth; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; positive regulation of epithelial cell proliferation involved in lung morphogenesis; branching involved in salivary gland morphogenesis; positive regulation of cell division; positive regulation of keratinocyte migration; surfactant homeostasis; positive regulation of peptidyl-tyrosine | |
| FGF8 | mesonephros development; anatomical structure morphogenesis; outflow tract septum morphogenesis; multicellular organismal development; gastrulation; positive regulation of cell proliferation; insulin receptor signaling pathway; gonad development; fibroblast growth factor receptor signaling pathway; metanephros development; odontogenesis; positive regulation of cell division; negative regulation of cardiac muscle tissue development; bone development; neuroepithelial cell differentiation; dopaminergic neuron differentiation | |
| FGF9 | male gonad development; positive regulation of MAPK cascade; inner ear morphogenesis; positive regulation of vascular endothelial growth factor receptor signaling pathway; embryonic limb morphogenesis; male sex determination; negative regulation of Wnt receptor signaling pathway; positive regulation of gene expression; protein import into nucleus; positive regulation of smoothened signaling pathway; regulation of timing of cell differentiation; embryonic digestive tract development; embryonic skeletal system development; positive regulation of epithelial cell proliferation; positive regulation of cell division; positive regulation of canonical Wnt receptor signaling pathway; lung-associated mesenchyme development; positive regulation of cardiac muscle cell proliferation; insulin receptor signaling pathway; positive regulation of cell proliferation; cell-cell signaling; signal transduction; fibroblast growth factor receptor signaling pathway; chondrocyte differentiation; positive regulation of mesenchymal cell | |
| FGFBP3 | positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of vascular permeability | |
| FGFR1 | insulin receptor signaling pathway; positive regulation of MAP kinase activity; positive regulation of cell proliferation; axon guidance; protein phosphorylation; regulation of transcription, DNA-dependent; neuron migration; skeletal system development; MAPK cascade; regulation of cell differentiation; positive regulation of MAPK cascade; positive regulation of neuron differentiation; protein autophosphorylation; phosphatidylinositol-mediated signaling; skeletal system morphogenesis; chordate embryonic development; fibroblast growth factor receptor signaling pathway; positive regulation of phospholipase activity; positive regulation of phospholipase C activity; positive regulation of phosphatidylinositol 3-kinase cascade; cell migration; peptidyl-tyrosine phosphorylation | |
| FGFR1OP2 | response to wounding | |
| FGFR2 | lung development; prostate epithelial cord elongation; ventricular cardiac muscle tissue morphogenesis; positive regulation of cardiac muscle cell proliferation; limb bud formation; bone development; bone morphogenesis; branching involved in prostate gland morphogenesis; branching involved in salivary gland morphogenesis; bud elongation involved in lung branching; lung lobe morphogenesis; lung-associated mesenchyme development; positive regulation of epithelial cell proliferation involved in lung morphogenesis; prostate gland morphogenesis; positive regulation of cell division; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; fibroblast growth factor receptor signaling pathway involved in mammary gland specification; lateral sprouting from an epithelium; mammary gland bud formation; epithelial cell proliferation involved in salivary gland morphogenesis; branch elongation | |
| FGFR3 | peptidyl-tyrosine phosphorylation; positive regulation of phospholipase activity; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of cell proliferation; positive regulation of phosphatidylinositol 3-kinase activity; JAK-STAT cascade; endochondral bone growth; chondrocyte differentiation; endochondral ossification; skeletal system development; MAPK cascade; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of apoptotic process; positive regulation of MAPK cascade; protein autophosphorylation; negative regulation of developmental growth; bone morphogenesis; positive regulation of ERK1 and ERK2 cascade; bone maturation; chondrocyte proliferation | |
| FGFR4 | regulation of lipid metabolic process; glucose homeostasis; positive regulation of proteolysis; protein autophosphorylation; positive regulation of metalloenzyme activity; positive regulation of DNA biosynthetic process; regulation of cholesterol homeostasis; regulation of bile acid biosynthetic process; positive regulation of ERK1 and ERK2 cascade; phosphate ion homeostasis; cell migration; regulation of extracellular matrix disassembly; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of cell proliferation; peptidyl-tyrosine phosphorylation | |
| FGFRL1 | protein phosphorylation; negative regulation of cell proliferation; fibroblast growth factor receptor signaling pathway; ventricular septum morphogenesis; diaphragm development; heart valve morphogenesis; regulation of cell growth; skeletal system development | |
| FGG | signal transduction; response to calcium ion; protein polymerization; platelet activation; blood coagulation; platelet degranulation | |
| FGGY | neuron homeostasis; cell death; carbohydrate metabolic process | |
| FGL1 | signal transduction | |
| FGL2 | signal transduction | |
| FGR | defense response to Gram-positive bacterium; regulation of protein kinase activity; protein autophosphorylation; positive regulation of cytokine secretion; regulation of phagocytosis; regulation of innate immune response; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of mast cell degranulation; positive regulation of cell migration; peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; regulation of cell shape; blood coagulation; integrin-mediated signaling pathway; protein phosphorylation; immune response-regulating cell surface receptor signaling pathway; response to virus | |
| FH | tricarboxylic acid cycle; fumarate metabolic process; malate metabolic process; small molecule metabolic process; homeostasis of number of cells within a tissue | |
| FHL1 | muscle organ development; negative regulation of G2/M transition of mitotic cell cycle; organ morphogenesis; cell differentiation; negative regulation of cell growth; negative regulation of G1/S transition of mitotic cell cycle; multicellular organismal development | |
| FHL2 | androgen receptor signaling pathway; heart trabecula formation; ventricular cardiac muscle cell development; atrial cardiac muscle cell development; positive regulation of transcription, DNA-dependent; small molecule metabolic process; cellular lipid metabolic process; negative regulation of apoptotic process; response to hormone stimulus; osteoblast differentiation; negative regulation of transcription from RNA polymerase II promoter | |
| FHL3 | muscle organ development; actin cytoskeleton organization | |
| FHOD1 | cellular component organization; actin cytoskeleton organization; positive regulation of transcription from RNA polymerase II promoter; positive regulation of stress fiber assembly | |
| FHOD3 | cellular component organization; actin cytoskeleton organization | |
| FIBIN | - | |
| FIBP | fibroblast growth factor receptor signaling pathway | |
| FIG4 | locomotory behavior; neuron development; phosphatidylinositol metabolic process; pigmentation; positive regulation of neuron projection development; cell death; vacuole organization | |
| FIGF | cell differentiation; vascular endothelial growth factor receptor signaling pathway; positive regulation of interleukin-6 production; regulation of vascular endothelial growth factor receptor signaling pathway; platelet activation; positive chemotaxis; induction of positive chemotaxis; positive regulation of cell division; positive regulation of mast cell chemotaxis; response to interleukin-1; platelet degranulation; blood coagulation; multicellular organismal development; positive regulation of cell proliferation; response to hypoxia; angiogenesis | |
| FIGN | locomotory behavior | |
| FIGNL1 | negative regulation of apoptotic process; ATP metabolic process; osteoblast proliferation; osteoblast differentiation; regulation of cell cycle | |
| FILIP1 | - | |
| FILIP1L | - | |
| FIP1L1 | mRNA processing | |
| FIS1 | mitochondrial fission; mitochondrion degradation; release of cytochrome c from mitochondria; apoptotic process; elevation of cytosolic calcium ion concentration; mitochondrial fragmentation involved in apoptosis; elevation of mitochondrial calcium ion concentration; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; calcium-mediated signaling using intracellular calcium source; reduction of endoplasmic reticulum calcium ion concentration; peroxisome fission | |
| FITM2 | cellular triglyceride homeostasis; lipid particle organization; regulation of cell morphogenesis; positive regulation of sequestering of triglyceride; regulation of triglyceride biosynthetic process; cytoskeleton organization | |
| FIZ1 | regulation of transcription, DNA-dependent | |
| FKBP11 | protein peptidyl-prolyl isomerization; peptidyl-proline modification; protein folding | |
| FKBP5 | peptidyl-proline modification; protein folding; protein peptidyl-prolyl isomerization | |
| FKBP8 | peptidyl-proline modification; apoptotic process; protein folding; protein peptidyl-prolyl isomerization; intracellular signal transduction; interspecies interaction between organisms | |
| FLAD1 | FAD biosynthetic process; vitamin metabolic process; water-soluble vitamin metabolic process; riboflavin metabolic process; Mo-molybdopterin cofactor biosynthetic process; small molecule metabolic process | |
| FLCN | regulation of protein phosphorylation | |
| FLG | multicellular organismal development; keratinocyte differentiation | |
| FLG2 | - | |
| FLII | regulation of transcription, DNA-dependent; muscle contraction; multicellular organismal development | |
| FLNA | negative regulation of protein catabolic process; protein stabilization; positive regulation of transcription factor import into nucleus; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of sequence-specific DNA binding transcription factor activity; early endosome to late endosome transport; establishment of protein localization; spindle assembly involved in mitosis; receptor clustering; actin crosslink formation; cytoplasmic sequestering of protein; cell junction assembly; actin cytoskeleton reorganization; platelet activation; blood coagulation; inhibition of adenylate cyclase activity by dopamine receptor signaling pathway; platelet degranulation; protein localization at cell surface | |
| FLNB | actin cytoskeleton organization; cell differentiation; cytokine-mediated signaling pathway; muscle organ development; multicellular organismal development; signal transduction; cytoskeletal anchoring at plasma membrane | |
| FLNC | cell junction assembly; muscle fiber development | |
| FLOT2 | cell adhesion; epidermis development | |
| FLRT1 | cell adhesion | |
| FLRT2 | cell adhesion | |
| FLRT3 | cell adhesion | |
| FLT1 | positive regulation of angiogenesis; peptidyl-tyrosine phosphorylation; cell differentiation; positive regulation of cell migration; intracellular receptor mediated signaling pathway; positive regulation of vascular endothelial growth factor receptor signaling pathway; cellular response to vascular endothelial growth factor stimulus; vascular endothelial growth factor signaling pathway; positive regulation of MAP kinase activity; positive regulation of MAPK cascade; positive regulation of phosphatidylinositol 3-kinase activity; vascular endothelial growth factor receptor signaling pathway; protein autophosphorylation; blood vessel morphogenesis; embryonic morphogenesis; positive regulation of smooth muscle cell proliferation; positive regulation of phosphatidylinositol 3-kinase cascade; cell migration; activation of MAPKK activity; response to hypoxia; monocyte chemotaxis; chemotaxis; regulation of smooth muscle contraction; multicellular organismal development; female pregnancy; positive regulation of cell p | |
| FLT3 | hemopoiesis; lymphocyte differentiation; vascular endothelial growth factor signaling pathway; positive regulation of tyrosine phosphorylation of STAT protein; regulation of apoptotic process; positive regulation of MAP kinase activity; positive regulation of MAPK cascade; positive regulation of phosphatidylinositol 3-kinase activity; negative regulation of B cell differentiation; protein autophosphorylation; cellular response to cytokine stimulus; cytokine-mediated signaling pathway; peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; negative regulation of cell proliferation; positive regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; pro-T cell differentiation; pro-B cell differentiation; myeloid progenitor cell differentiation | |
| FLT4 | positive regulation of protein kinase C signaling cascade; peptidyl-tyrosine phosphorylation; positive regulation of MAPK cascade; negative regulation of apoptotic process; vascular endothelial growth factor signaling pathway; cellular response to vascular endothelial growth factor stimulus; positive regulation of JNK cascade; protein autophosphorylation; positive regulation of ERK1 and ERK2 cascade; regulation of blood vessel remodeling; blood vessel morphogenesis; vascular endothelial growth factor receptor signaling pathway; vasculature development; positive regulation vascular endothelial growth factor production; positive regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; sprouting angiogenesis; lymphangiogenesis; positive regulation of endothelial cell proliferation; positive regulation of protein phosphorylation; positive regulation of endothelial cell migration | |
| FLVCR2 | transmembrane transport; heme transport | |
| FMN2 | polar body extrusion after meiotic divisions; intracellular signal transduction; actin cytoskeleton organization; meiotic chromosome movement towards spindle pole; cellular component organization; establishment of meiotic spindle localization; oogenesis; multicellular organismal development; meiotic metaphase I | |
| FMNL1 | substrate-dependent cell migration; regulation of cell shape; cellular process; cellular component organization; cortical actin cytoskeleton organization | |
| FMNL3 | cellular component organization; regulation of cell shape; cytoskeleton organization; cell migration; actin cytoskeleton organization | |
| FMO1 | NADPH oxidation; small molecule metabolic process; response to lipopolysaccharide; response to osmotic stress; xenobiotic metabolic process; organic acid metabolic process; toxin metabolic process | |
| FMO2 | oxygen metabolic process; NADPH oxidation; small molecule metabolic process; drug metabolic process; toxin metabolic process; xenobiotic metabolic process; NADP metabolic process; organic acid metabolic process | |
| FMO3 | xenobiotic metabolic process; drug metabolic process; small molecule metabolic process | |
| FMO5 | oxidation-reduction process | |
| FMR1 | transport; central nervous system development; negative regulation of translational initiation; mRNA transport | |
| FMR1NB | - | |
| FN1 | angiogenesis; leukocyte migration; substrate adhesion-dependent cell spreading; platelet activation; peptide cross-linking; cell migration; regulation of cell shape; blood coagulation; cell adhesion; acute-phase response; platelet degranulation; response to wounding | |
| FN3KRP | - | |
| FNBP4 | - | |
| FNDC3A | spermatid development; fertilization; cell-cell adhesion; Sertoli cell development | |
| FNDC9 | - | |
| FNIP1 | regulation of protein phosphorylation | |
| FNTA | positive regulation of tubulin deacetylation; positive regulation of deacetylase activity; protein geranylgeranylation; protein farnesylation; transforming growth factor beta receptor signaling pathway; cellular component disassembly involved in apoptosis; apoptotic process | |
| FOCAD | - | |
| FOS | TRIF-dependent toll-like receptor signaling pathway; response to lipopolysaccharide; cellular response to reactive oxygen species; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; response to cytokine stimulus; cellular response to hormone stimulus; response to progesterone stimulus; response to drug; innate immune response; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of sequence-specific DNA binding transcription factor activity; stress-activated MAPK cascade; response to corticosterone stimulus; response to cAMP; cellular response to calcium ion; SMAD protein signal transduction; sleep; conditioned taste aversion; toll-like receptor signaling pathway; cellular response to extracellular stimulus; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; DNA me | |
| FOSL1 | regulation of transcription from RNA polymerase II promoter; response to cytokine stimulus; transcription from RNA polymerase II promoter; chemotaxis; cellular defense response; female pregnancy; learning; positive regulation of cell proliferation; negative regulation of cell proliferation; response to mechanical stimulus; response to virus; response to gravity; response to organic cyclic compound; cellular response to extracellular stimulus; response to progesterone stimulus; response to drug; response to hydrogen peroxide; positive regulation of cell cycle; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter during mitosis; response to corticosterone stimulus; response to cAMP | |
| FOSL2 | regulation of transcription from RNA polymerase II promoter; positive regulation of fibroblast proliferation; cell death | |
| FOXA3 | positive regulation of hepatocyte differentiation; cellular glucose homeostasis; regulation of transcription, DNA-dependent; spermatogenesis; brain development; negative regulation of cell proliferation; cellular response to starvation; embryo development; chromatin modification; neural plate anterior/posterior regionalization; endocrine pancreas development; response to nutrient levels; positive regulation of transcription from RNA polymerase II promoter; neuron fate specification; regulation of sequence-specific DNA binding transcription factor activity; epithelial tube branching involved in lung morphogenesis; lung epithelial cell differentiation; cell differentiation | |
| FOXF2 | extracellular matrix organization; palate development; regulation of sequence-specific DNA binding transcription factor activity; genitalia development; embryonic digestive tract development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; establishment of planar polarity of embryonic epithelium; tissue development; embryo development; pattern specification process; epithelial to mesenchymal transition | |
| FOXG1 | tissue development; axon midline choice point recognition; dorsal/ventral pattern formation; nonmotile primary cilium assembly; central nervous system neuron development; hindbrain development; regulation of sequence-specific DNA binding transcription factor activity; embryo development ending in birth or egg hatching; brain development; regulation of mitotic cell cycle; multicellular organismal development; regulation of transcription, DNA-dependent; positive regulation of neuroblast proliferation; inner ear morphogenesis; nose development; negative regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell cycle | |
| FOXJ3 | organ development; regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription, DNA-dependent; tissue development; pattern specification process; embryo development | |
| FOXK1 | negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; pattern specification process; muscle organ development; negative regulation of cell growth; embryo development; tissue development; positive regulation of transcription, DNA-dependent; cell differentiation; regulation of sequence-specific DNA binding transcription factor activity | |
| FOXL2NB | - | |
| FOXM1 | regulation of cell growth; regulation of reactive oxygen species metabolic process; G2/M transition of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; vasculogenesis; liver development; DNA repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; cell cycle; pattern specification process; positive regulation of cell proliferation; tissue development; positive regulation of double-strand break repair; negative regulation of cell aging; regulation of cell cycle arrest; regulation of sequence-specific DNA binding transcription factor activity; regulation of Ras protein signal transduction; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; regulation of cell proliferation; negative regulation of | |
| FOXN1 | transcription from RNA polymerase II promoter; organ morphogenesis; keratinocyte differentiation; thymus development; epithelial cell proliferation; regulation of sequence-specific DNA binding transcription factor activity; regulation of transcription from RNA polymerase II promoter; defense response; pattern specification process; epidermis development; embryo development | |
| FOXP1 | sarcomere organization; positive regulation of cardiac muscle cell differentiation; in utero embryonic development; regulation of sequence-specific DNA binding transcription factor activity; positive regulation of mesenchymal cell proliferation; pre-B cell differentiation; smooth muscle tissue development; positive regulation of immunoglobulin production; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; pattern specification process; ventral spinal cord development; heart development; skeletal muscle tissue development; embryo development; motor axon guidance; lung development; cardiac muscle cell differentiation; regulation of cardiac muscle cell proliferation; positive regulation of epithelial cell proliferation involved in lung morphogenesis; immunoglobulin V(D)J recombination | |
| FOXP2 | positive regulation of mesenchymal cell proliferation; negative regulation of transcription, DNA-dependent; pattern specification process; cerebellum development; skeletal muscle tissue development; post-embryonic development; embryo development; camera-type eye development; vocal learning; lung alveolus development; smooth muscle tissue development; regulation of sequence-specific DNA binding transcription factor activity; righting reflex; positive regulation of epithelial cell proliferation involved in lung morphogenesis; growth; putamen development; caudate nucleus development; cerebral cortex development | |
| FOXP3 | negative regulation of interleukin-2 production; positive regulation of mesenchymal cell proliferation; chromatin remodeling; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; positive regulation of transforming growth factor beta1 production; positive regulation of immature T cell proliferation in thymus; positive regulation of histone acetylation; positive regulation of peripheral T cell tolerance induction; negative regulation of T cell cytokine production; negative regulation of chronic inflammatory response; growth; myeloid cell homeostasis; T cell mediated immunity; negative regulation of histone acetylation; tolerance induction to self antigen; positive regulation of T cell anergy; regulation of immunoglobulin production; putamen development; negative regulation of interleukin-4 production; negative regulation of interleukin-5 production; negative regulation of interleukin-6 production; negative regulation of interleukin-10 production; negative regulation | |
| FOXP4 | pattern specification process; regulation of sequence-specific DNA binding transcription factor activity; heart development; tissue development; embryonic foregut morphogenesis | |
| FOXQ1 | pattern specification process; embryo development; positive regulation of transcription from RNA polymerase II promoter; hair follicle morphogenesis; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; DNA fragmentation involved in apoptotic nuclear change; regulation of sequence-specific DNA binding transcription factor activity | |
| FOXR1 | organ development; pattern specification process; embryo development; tissue development; regulation of sequence-specific DNA binding transcription factor activity | |
| FOXRED2 | ER-associated protein catabolic process | |
| FOXS1 | embryonic heart tube development; ventricular cardiac muscle tissue morphogenesis; positive regulation of multicellular organism growth; camera-type eye development; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of organ growth; vascular endothelial growth factor receptor signaling pathway; paraxial mesodermal cell fate commitment; embryonic viscerocranium morphogenesis; artery morphogenesis; regulation of blood vessel size; neuromuscular process controlling balance; collagen fibril organization; neural crest cell fate commitment; insulin receptor signaling pathway; multicellular organismal development; Notch signaling pathway; anti-apoptosis; regulation of transcription, DNA-dependent; blood vessel remodeling; lymphangiogenesis; somitogenesis; ureteric bud development; metanephros development; vasculogenesis; patterning of blood vessels; b | |
| FPGT | fucose metabolic process | |
| FPR1 | G-protein signaling, coupled to cAMP nucleotide second messenger; activation of MAPK activity; cellular component movement; chemotaxis; signal transduction; G-protein coupled receptor signaling pathway; nitric oxide mediated signal transduction | |
| FPR2 | cellular component movement; chemotaxis; inflammatory response; cell adhesion; G-protein coupled receptor signaling pathway | |
| FPR3 | cellular component movement; chemotaxis; signal transduction | |
| FRA10AC1 | - | |
| FREM2 | cell communication; morphogenesis of an epithelium; cell adhesion; homophilic cell adhesion; multicellular organismal development | |
| FRK | protein phosphorylation; negative regulation of cell proliferation; cell differentiation | |
| FRMD1 | - | |
| FRMD4A | - | |
| FRMD5 | - | |
| FRMD6 | - | |
| FRMD7 | regulation of neuron projection development; nervous system development | |
| FRMD8 | - | |
| FRMPD1 | - | |
| FRMPD2 | tight junction assembly | |
| FRMPD4 | positive regulation of synapse structural plasticity | |
| FRRS1 | electron transport chain; transport | |
| FRRS1L | - | |
| FRS2 | neuroblast proliferation; activation of phospholipase C activity; G-protein coupled receptor signaling pathway; activation of MAPKK activity; activation of MAPK activity; gastrulation with mouth forming second; organ induction; ventricular septum development; transmembrane receptor protein tyrosine phosphatase signaling pathway; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; insulin receptor signaling pathway; regulation of epithelial cell proliferation; nerve growth factor receptor signaling pathway; optic placode formation involved in camera-type eye formation; forebrain development; anterior/posterior axis specification, embryo; fibroblast growth factor receptor signaling pathway | |
| FRS3 | signal transduction; fibroblast growth factor receptor signaling pathway | |
| FRY | regulation of transcription, DNA-dependent | |
| FRYL | regulation of transcription, DNA-dependent | |
| FSCB | peptidyl-serine phosphorylation | |
| FSCN3 | - | |
| FSD1 | cell cycle; cell division; mitosis | |
| FSHR | activation of adenylate cyclase activity by G-protein signaling pathway; transcytosis; follicle-stimulating hormone signaling pathway; spermatogenesis, exchange of chromosomal proteins; regulation of chromosome organization; female gonad development; gonad development; female gamete generation; spermatogenesis; G-protein coupled receptor signaling pathway; male gonad development | |
| FSIP1 | - | |
| FSIP2 | - | |
| FST | hemopoietic progenitor cell differentiation; positive regulation of hair follicle development; negative regulation of follicle-stimulating hormone secretion; negative regulation of activin receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; signal transduction | |
| FSTL4 | - | |
| FSTL5 | - | |
| FTCD | folic acid-containing compound metabolic process; histidine catabolic process; cytoskeleton organization; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| FTMT | positive regulation of transferase activity; positive regulation of lyase activity; positive regulation of oxidoreductase activity; iron ion transport; cellular iron ion homeostasis; positive regulation of cell proliferation | |
| FTO | oxidative single-stranded DNA demethylation; DNA dealkylation involved in DNA repair; oxidative single-stranded RNA demethylation; temperature homeostasis; regulation of respiratory system process; adipose tissue development; regulation of white fat cell proliferation; regulation of multicellular organism growth; RNA repair; oxidative demethylation; DNA demethylation; regulation of lipid storage | |
| FTSJ3 | RNA methylation; rRNA processing | |
| FUBP3 | positive regulation of transcription, DNA-dependent; regulation of gene expression; transcription, DNA-dependent | |
| FUCA1 | carbohydrate metabolic process; fucose metabolic process; glycosaminoglycan catabolic process | |
| FUCA2 | carbohydrate metabolic process; fucose metabolic process | |
| FUK | metabolic process | |
| FURIN | negative regulation of nerve growth factor production; regulation of protein catabolic process; peptide biosynthetic process; post-translational protein modification; cellular protein metabolic process; nerve growth factor receptor signaling pathway; positive regulation of membrane protein ectodomain proteolysis; regulation of endopeptidase activity; positive regulation of transforming growth factor beta receptor signaling pathway; nerve growth factor processing; negative regulation of low-density lipoprotein particle receptor catabolic process; peptidyl-glutamic acid carboxylation; peptide hormone processing; nerve growth factor production; negative regulation of transforming growth factor beta1 production; secretion by cell; positive regulation of cell migration; viral assembly, maturation, egress, and release; signal peptide processing; proteolysis; transforming growth factor beta receptor signaling pathway; Notch signaling pathway; aging; cell proliferation; protein processing | |
| FUT1 | carbohydrate metabolic process; protein glycosylation; fucosylation; L-fucose catabolic process | |
| FUT2 | carbohydrate metabolic process; protein glycosylation; fucosylation; L-fucose catabolic process | |
| FUT8 | L-fucose catabolic process; in utero embryonic development; protein N-linked glycosylation; N-glycan processing; transforming growth factor beta receptor signaling pathway; integrin-mediated signaling pathway; respiratory gaseous exchange; oligosaccharide biosynthetic process; cell migration; protein N-linked glycosylation via asparagine; protein glycosylation in Golgi; N-glycan fucosylation; receptor metabolic process; post-translational protein modification; cellular protein metabolic process | |
| FXR1 | muscle organ development; negative regulation of translation; cell differentiation; apoptotic process; multicellular organismal development | |
| FXYD4 | ion transport | |
| FXYD5 | negative regulation of calcium-dependent cell-cell adhesion; microvillus assembly; ion transport | |
| FYCO1 | plus-end-directed vesicle transport along microtubule; transport | |
| FYN | intracellular protein kinase cascade; calcium ion transport; viral reproduction; leukocyte migration; T cell receptor signaling pathway; regulation of defense response to virus by virus; interspecies interaction between organisms; T cell costimulation; platelet activation; protein phosphorylation; multicellular organismal development; axon guidance; blood coagulation; learning; feeding behavior | |
| FYTTD1 | transport; mRNA export from nucleus | |
| FZD1 | planar cell polarity pathway involved in neural tube closure; negative regulation of canonical Wnt receptor signaling pathway; cellular response to peptide hormone stimulus; lung alveolus development; cellular response to growth factor stimulus; cellular response to vitamin D; cell-cell signaling; negative regulation of catenin import into nucleus; epithelial cell differentiation; negative regulation of BMP signaling pathway; neuron differentiation; embryo development; gonad development; brain development; axonogenesis; hard palate development; Wnt receptor signaling pathway, calcium modulating pathway; G-protein signaling, coupled to cGMP nucleotide second messenger; outflow tract morphogenesis; muscular septum morphogenesis; membranous septum morphogenesis; vasculature development; positive regulation of protein phosphorylation; response to drug; canonical Wnt receptor signaling pathway; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription, | |
| FZD10 | neuron differentiation; cellular response to retinoic acid; canonical Wnt receptor signaling pathway; positive regulation of JUN kinase activity; non-canonical Wnt receptor signaling pathway; negative regulation of Rho GTPase activity; regulation of actin cytoskeleton organization; positive regulation of Rac GTPase activity; embryo development; gonad development; vasculature development; brain development | |
| FZD3 | inner ear morphogenesis; cell proliferation in midbrain; neuron differentiation; facial nucleus development; gonad development; canonical Wnt receptor signaling pathway; commissural neuron axon guidance; establishment of planar polarity; neural tube closure; vasculature development; multicellular organismal development; G-protein signaling, coupled to cGMP nucleotide second messenger | |
| FZD4 | Wnt receptor signaling pathway; cellular response to retinoic acid; neuron differentiation; regulation of vascular endothelial growth factor receptor signaling pathway; locomotion involved in locomotory behavior; substrate adhesion-dependent cell spreading; extracellular matrix-cell signaling; progesterone secretion; positive regulation of transcription, DNA-dependent; positive regulation of sequence-specific DNA binding transcription factor activity; canonical Wnt receptor signaling pathway; retina vasculature morphogenesis in camera-type eye; cerebellum vasculature morphogenesis; retinal blood vessel morphogenesis; negative regulation of cell-substrate adhesion; embryo development; sensory perception of sound; brain development; Wnt receptor signaling pathway, calcium modulating pathway; vasculogenesis; blood vessel development | |
| FZD5 | anterior/posterior axis specification, embryo; post-embryonic camera-type eye development; embryonic camera-type eye development; neuron differentiation; embryonic axis specification; positive regulation of interferon-gamma production; T cell differentiation in thymus; Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of transcription from RNA polymerase II promoter; Spemann organizer formation; canonical Wnt receptor signaling pathway; labyrinthine layer blood vessel development; cellular response to molecule of bacterial origin; multicellular organismal development; apoptotic process; angiogenesis; gonad development; brain development; axonogenesis | |
| FZD6 | angiogenesis; establishment of planar polarity; neural tube closure; G-protein signaling, coupled to cGMP nucleotide second messenger; multicellular organismal development; axonogenesis; gonad development; cell proliferation in midbrain; non-canonical Wnt receptor signaling pathway; inner ear morphogenesis; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of canonical Wnt receptor signaling pathway | |
| FZD7 | satellite cell maintenance involved in skeletal muscle regeneration; T cell differentiation in thymus; somatic stem cell division; positive regulation of epithelial cell proliferation involved in wound healing; canonical Wnt receptor signaling pathway; mesenchymal to epithelial transition; cellular response to retinoic acid; positive regulation of JNK cascade; positive regulation of transcription, DNA-dependent; negative regulation of ectodermal cell fate specification; positive regulation of phosphorylation; non-canonical Wnt receptor signaling pathway; regulation of catenin import into nucleus; substrate adhesion-dependent cell spreading; neuron differentiation; stem cell maintenance; negative regulation of cell-substrate adhesion; gonad development; brain development; axonogenesis; multicellular organismal development; Wnt receptor signaling pathway, calcium modulating pathway; G-protein signaling, coupled to cGMP nucleotide second messenger; regulation of transcription, DNA-dependent; vasculature developm | |
| FZD9 | brain development; canonical Wnt receptor signaling pathway; B cell differentiation; embryo development; gonad development; learning or memory; vasculature development; nervous system development; neuroblast proliferation | |
| FZR1 | S phase of mitotic cell cycle; mitotic cell cycle; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; activation of anaphase-promoting complex activity; lens fiber cell differentiation; protein K11-linked ubiquitination; positive regulation of cell proliferation; phosphorylation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of cell aging; mitosis; DNA repair; G2/M transition DNA damage checkpoint; regulation of meiosis; positive regulation of protein catabolic process | |
| G2E3 | protein polyubiquitination; blastocyst development; protein modification process; multicellular organismal development; negative regulation of apoptotic process | |
| G3BP2 | regulation of small GTPase mediated signal transduction; transport; cytoplasmic sequestering of NF-kappaB; small GTPase mediated signal transduction; Ras protein signal transduction; mRNA transport | |
| G6PC3 | hexose transport; gluconeogenesis; carbohydrate metabolic process; transmembrane transport; glucose 6-phosphate metabolic process; small molecule metabolic process; dephosphorylation; glucose-6-phosphate transport; glucose transport | |
| GAA | heart morphogenesis; maltose metabolic process; cardiac muscle contraction; ventricular cardiac muscle tissue morphogenesis; neuromuscular process controlling balance; neuromuscular process controlling posture; muscle cell homeostasis; tongue morphogenesis; vacuolar sequestering; tissue development; locomotory behavior; lysosome organization; glucose metabolic process; sucrose metabolic process; glycogen catabolic process; carbohydrate metabolic process; diaphragm contraction; regulation of the force of heart contraction; muscle organ development | |
| GAB1 | epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; cell proliferation | |
| GAB3 | - | |
| GABARAPL1 | - | |
| GABBR2 | negative regulation of adenylate cyclase activity; synaptic transmission; gamma-aminobutyric acid signaling pathway; G-protein coupled receptor signaling pathway | |
| GABPB1 | regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter | |
| GABRA1 | chloride transport; transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; transmembrane transport | |
| GABRA2 | regulation of neurotransmitter levels; chloride transport; neurotransmitter transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; transmembrane transport | |
| GABRA4 | transmembrane transport; ion transmembrane transport; synaptic transmission; gamma-aminobutyric acid signaling pathway; chloride transport; transport | |
| GABRA6 | signal transduction; transport; chloride transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; synaptic transmission, GABAergic; transmembrane transport | |
| GABRB1 | synaptic transmission; transmembrane transport; ion transmembrane transport; signal transduction; chloride transport; transport | |
| GABRB2 | transport; chloride transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; transmembrane transport | |
| GABRE | gamma-aminobutyric acid signaling pathway; ion transport; transport | |
| GABRG1 | gamma-aminobutyric acid signaling pathway; ion transport; synaptic transmission | |
| GABRG2 | chloride transport; transmembrane transport; ion transmembrane transport; synaptic transmission; gamma-aminobutyric acid signaling pathway; transport | |
| GABRP | ion transport | |
| GABRR1 | transmembrane transport; ion transmembrane transport; synaptic transmission; gamma-aminobutyric acid signaling pathway; chloride transport; transport | |
| GAD2 | glutamate decarboxylation to succinate; synaptic transmission; neurotransmitter secretion; carboxylic acid metabolic process; neurotransmitter biosynthetic process; response to drug | |
| GADD45GIP1 | interspecies interaction between organisms; cell cycle | |
| GADL1 | carboxylic acid metabolic process | |
| GAK | cell cycle | |
| GAL3ST1 | spermatogenesis; sphingolipid metabolic process; protein N-linked glycosylation; glycosphingolipid metabolic process; galactosylceramide biosynthetic process; biosynthetic process; myelination; small molecule metabolic process | |
| GAL3ST2 | biosynthetic process | |
| GAL3ST4 | sulfur compound metabolic process; cell-cell signaling; biosynthetic process; glycoprotein metabolic process; oligosaccharide metabolic process; proteoglycan biosynthetic process | |
| GALC | carbohydrate metabolic process; sphingolipid metabolic process; galactosylceramide catabolic process; glycosphingolipid metabolic process; small molecule metabolic process | |
| GALK1 | small molecule metabolic process; carbohydrate phosphorylation; galactitol metabolic process; galactose catabolic process; galactose metabolic process; carbohydrate metabolic process | |
| GALM | hexose metabolic process; carbohydrate metabolic process | |
| GALNS | - | |
| GALNT1 | protein O-linked glycosylation via threonine; post-translational protein modification; cellular protein metabolic process; protein O-linked glycosylation; O-glycan processing; protein O-linked glycosylation via serine | |
| GALNT11 | cellular protein metabolic process; post-translational protein modification; O-glycan processing; carbohydrate metabolic process | |
| GALNT12 | post-translational protein modification; O-glycan processing; cellular protein metabolic process | |
| GALNT13 | O-glycan processing; cellular protein metabolic process; post-translational protein modification | |
| GALNT14 | O-glycan processing; post-translational protein modification; carbohydrate metabolic process; cellular protein metabolic process | |
| GALNT15 | - | |
| GALNT16 | - | |
| GALNT2 | immunoglobulin biosynthetic process; O-glycan processing; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine; post-translational protein modification; cellular protein metabolic process | |
| GALNT3 | cellular protein metabolic process; post-translational protein modification; protein O-linked glycosylation via threonine; protein O-linked glycosylation via serine; carbohydrate metabolic process; O-glycan processing | |
| GALNT5 | glycosaminoglycan biosynthetic process; cellular protein metabolic process; O-glycan processing; post-translational protein modification | |
| GALNT6 | protein O-linked glycosylation; O-glycan processing; post-translational protein modification; cellular protein metabolic process | |
| GALNT7 | post-translational protein modification; cellular protein metabolic process; O-glycan processing; protein O-linked glycosylation; carbohydrate metabolic process | |
| GALNT8 | post-translational protein modification; cellular protein metabolic process; O-glycan processing | |
| GALNT9 | cellular protein metabolic process; protein O-linked glycosylation; post-translational protein modification; O-glycan processing | |
| GALNTL6 | - | |
| GALR1 | activation of adenylate cyclase activity by G-protein signaling pathway; neuropeptide signaling pathway; negative regulation of adenylate cyclase activity; digestion | |
| GALR2 | activation of adenylate cyclase activity by G-protein signaling pathway; phosphatidylinositol metabolic process; inositol phosphate metabolic process; neuron projection development; feeding behavior; learning or memory; digestion; multicellular organismal development; synaptic transmission; elevation of cytosolic calcium ion concentration; G-protein signaling, coupled to cAMP nucleotide second messenger; cell surface receptor signaling pathway; muscle contraction | |
| GALR3 | negative regulation of adenylate cyclase activity; feeding behavior; learning or memory; synaptic transmission; neuropeptide signaling pathway | |
| GAMT | cellular nitrogen compound metabolic process; small molecule metabolic process; methylation; muscle contraction; creatine biosynthetic process; creatine metabolic process | |
| GAN | cell death | |
| GANAB | carbohydrate metabolic process; protein folding; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process | |
| GANC | carbohydrate metabolic process | |
| GAP43 | activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; response to wounding; nervous system development; multicellular organismal development; cell differentiation; regulation of growth; regulation of filopodium assembly | |
| GAPVD1 | regulation of protein transport; regulation of small GTPase mediated signal transduction; signal transduction; endocytosis | |
| GARNL3 | regulation of small GTPase mediated signal transduction | |
| GART | purine base metabolic process; purine nucleotide biosynthetic process; 'de novo' IMP biosynthetic process; biosynthetic process; purine base biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; response to organic substance; response to inorganic substance; small molecule metabolic process; organ development; nucleobase-containing small molecule metabolic process | |
| GAS2 | cellular component disassembly involved in apoptosis; apoptotic process; cell cycle; cell cycle arrest; regulation of cell shape | |
| GAS2L2 | cell cycle arrest; negative regulation of microtubule depolymerization; microtubule bundle formation | |
| GAS2L3 | cell cycle arrest | |
| GAS7 | actin filament bundle assembly; regulation of transcription, DNA-dependent; cell cycle arrest; multicellular organismal development; nervous system development; regulation of cell shape; actin filament polymerization; neuron differentiation; neuron projection morphogenesis | |
| GAS8 | negative regulation of cell proliferation; sperm motility | |
| GATA1 | eosinophil differentiation; basophil differentiation; blood coagulation; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; transcription from RNA polymerase II promoter; regulation of definitive erythrocyte differentiation; regulation of glycoprotein biosynthetic process; male gonad development; negative regulation of cell proliferation; cell-cell signaling; erythrocyte development; negative regulation of transcription regulatory region DNA binding; cellular response to thyroid hormone stimulus; dendritic cell differentiation; transcriptional activation by promoter-enhancer looping; cellular response to follicle-stimulating hormone stimulus; cellular response to cAMP; platelet aggregation; Sertoli cell development; positive regulation of peptidyl-tyrosine phosphorylation; platelet formation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of anti-apoptosis; negative regulation of apoptotic process; eosinophil fate co | |
| GATA2 | transcription, DNA-dependent; negative regulation of neural precursor cell proliferation; negative regulation of fat cell proliferation; semicircular canal development; definitive hemopoiesis; positive regulation of phagocytosis; homeostasis of number of cells within a tissue; neuron fate commitment; cell maturation; negative regulation of fat cell differentiation; negative regulation of myeloid cell differentiation; positive regulation of erythrocyte differentiation; negative regulation of macrophage differentiation; positive regulation of megakaryocyte differentiation; negative regulation of Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; embryonic placenta development; cell fate determination; urogenital system development; negative regulation of transcription from RNA polymerase II promoter; ventral spinal cord interneuron differentiation; cell differentiation in hindbrain; central nervous system neuron development; pituitary gland developm | |
| GATA3 | cardiac right ventricle morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell fate determination; kidney development; mesonephros development; aortic valve morphogenesis; nephric duct morphogenesis; sympathetic nervous system development; anatomical structure formation involved in morphogenesis; negative regulation of inflammatory response; T cell receptor signaling pathway; positive regulation of protein kinase B signaling cascade; pharyngeal system development; uterus development; mesenchymal to epithelial transition; ureteric bud formation; canonical Wnt receptor signaling pathway involved in metanephric kidney development; cellular response to interleukin-4; cellular response to tumor necrosis factor; positive regulation of ureteric bud formation; ventricular septum development; nephric duct formation; regulation of nephron tubule epithelial cell differentiation; lymphocyte migration; negative regulation of cell motility; negative regulation of endothelial cell apoptosi | |
| GATA5 | blood coagulation; positive regulation of transcription from RNA polymerase II promoter; intestinal epithelial cell differentiation | |
| GATA6 | cellular response to gonadotropin stimulus; response to estrogen stimulus; positive regulation of angiogenesis; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; organ formation; smooth muscle cell differentiation; blood coagulation; cellular response to hypoxia; lung saccule development; positive regulation of cell cycle arrest; response to growth factor stimulus; cardiac vascular smooth muscle cell differentiation; intestinal epithelial cell differentiation; Type II pneumocyte differentiation; Clara cell differentiation; response to cAMP; positive regulation of cardioblast differentiation; cardiac muscle cell differentiation; positive regulation of cardiac muscle cell proliferation; in utero embryonic development; response to toxin; male gonad development; endodermal cell fate determination; negative regulation of transcription from RNA polymerase II promoter; positive regulation of BMP signaling pathway; epithelial cell differentiatio | |
| GATAD2B | - | |
| GATB | translation; glutaminyl-tRNAGln biosynthesis via transamidation; mitochondrial translation | |
| GBA2 | lipid metabolic process; small molecule metabolic process; O-glycoside catabolic process; sphingolipid metabolic process; glucosylceramide catabolic process; glycosphingolipid metabolic process; bile acid metabolic process | |
| GBF1 | retrograde vesicle-mediated transport, Golgi to ER; COPI coating of Golgi vesicle; post-Golgi vesicle-mediated transport; cellular membrane organization; regulation of ARF protein signal transduction | |
| GBP4 | - | |
| GBP5 | cellular response to interferon-gamma | |
| GBP6 | - | |
| GBP7 | - | |
| GBX1 | regulation of transcription, DNA-dependent | |
| GC | steroid metabolic process; vitamin D metabolic process; small molecule metabolic process; vitamin transport | |
| GCC1 | protein targeting to Golgi | |
| GCC2 | recycling endosome to Golgi transport; Golgi ribbon formation; protein targeting to lysosome; regulation of protein exit from endoplasmic reticulum; Golgi to plasma membrane protein transport; retrograde transport, endosome to Golgi; late endosome to Golgi transport; microtubule anchoring; protein localization in Golgi apparatus; microtubule organizing center organization; protein transport; protein targeting to Golgi | |
| GCDH | acyl-CoA metabolic process; fatty-acyl-CoA biosynthetic process; small molecule metabolic process; cellular nitrogen compound metabolic process; fatty acid oxidation; lysine catabolic process | |
| GCFC2 | negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| GCH1 | response to pain; vasodilation; dopamine biosynthetic process; protein heterooligomerization; pteridine-containing compound biosynthetic process; small molecule metabolic process; negative regulation of blood pressure; nitric oxide metabolic process; tetrahydrofolate biosynthetic process; neuromuscular process controlling posture; protein homooligomerization; dihydrobiopterin metabolic process; positive regulation of nitric-oxide synthase activity; regulation of nitric-oxide synthase activity; response to lipopolysaccharide; response to interferon-gamma; regulation of lung blood pressure; regulation of blood pressure; induction of apoptosis; nitric oxide biosynthetic process; tetrahydrobiopterin biosynthetic process; protein complex assembly; GTP catabolic process; response to tumor necrosis factor | |
| GCHFR | small molecule metabolic process; protein complex assembly; nitric oxide biosynthetic process; negative regulation of biosynthetic process; neurotransmitter metabolic process; negative regulation of GTP cyclohydrolase I activity; protein heterooligomerization; regulation of nitric-oxide synthase activity; nitric oxide metabolic process | |
| GCKR | small molecule metabolic process; triglyceride homeostasis; transmembrane transport; urate metabolic process; positive regulation of glucokinase activity; negative regulation of glucokinase activity; glucose transport; regulation of glucose transport; positive regulation of gene expression; response to fructose stimulus; hexose transport; carbohydrate metabolic process; cellular glucose homeostasis; protein import into nucleus, translocation | |
| GCLM | negative regulation of neuron apoptosis; regulation of mitochondrial depolarization; response to nitrosative stress; regulation of blood vessel size; small molecule metabolic process; response to drug; positive regulation of glutamate-cysteine ligase activity; cellular nitrogen compound metabolic process; response to oxidative stress; xenobiotic metabolic process; glutathione biosynthetic process; glutamate metabolic process; cysteine metabolic process; sulfur amino acid metabolic process | |
| GCN1 | translation; regulation of translation | |
| GCNT1 | protein O-linked glycosylation; O-glycan processing; post-translational protein modification; cellular protein metabolic process | |
| GCNT2 | metabolic process; multicellular organismal development; glycosaminoglycan biosynthetic process | |
| GCNT3 | O-glycan processing; cellular protein metabolic process; protein O-linked glycosylation; carbohydrate metabolic process; post-translational protein modification | |
| GDA | nucleobase-containing compound metabolic process; purine base metabolic process; purine nucleotide catabolic process; nervous system development; nucleobase-containing small molecule metabolic process; small molecule metabolic process | |
| GDAP2 | response to retinoic acid | |
| GDF10 | cerebellum development; skeletal system development; transforming growth factor beta receptor signaling pathway; regulation of ossification; growth; ovulation cycle; positive regulation of osteoblast differentiation; response to transforming growth factor beta stimulus | |
| GDF15 | signal transduction; transforming growth factor beta receptor signaling pathway; cell-cell signaling | |
| GDF3 | formation of anatomical boundary; primitive streak formation; notochord development; growth; somite rostral/caudal axis specification; mesoderm development; endoderm development; response to dietary excess; in utero embryonic development; eye development; skeletal system development | |
| GDF5 | embryonic limb morphogenesis; cell-cell signaling; positive regulation of chondrocyte differentiation; post-embryonic hindlimb morphogenesis; forelimb morphogenesis; growth; regulation of multicellular organism growth; regulation of apoptotic process; cartilage development; transforming growth factor beta receptor signaling pathway | |
| GDF6 | positive regulation of pathway-restricted SMAD protein phosphorylation; pathway-restricted SMAD protein phosphorylation; positive regulation of transcription, DNA-dependent; positive regulation of neuron differentiation; growth; activin receptor signaling pathway; BMP signaling pathway | |
| GDF9 | regulation of progesterone secretion; negative regulation of cell growth; positive regulation of cell proliferation; female gamete generation; transforming growth factor beta receptor signaling pathway; oocyte growth | |
| GDI1 | signal transduction; regulation of small GTPase mediated signal transduction; protein transport; small GTPase mediated signal transduction | |
| GDI2 | small GTPase mediated signal transduction; protein transport; regulation of small GTPase mediated signal transduction; signal transduction | |
| GDNF | negative regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; mRNA stabilization; enteric nervous system development; sympathetic nervous system development; regulation of dopamine uptake; regulation of morphogenesis of a branching structure; positive regulation of ureteric bud formation; anti-apoptosis; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; positive regulation of branching involved in ureteric bud morphogenesis; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of monooxygenase activity; neuron projection development; peristalsis; postganglionic parasympathetic nervous system development; adult locomotory behavior; axon guidance; nervous system development; signal transduction; postsynaptic membrane organization; organ induction; neural crest cell migration; metanephros development; positive regulation of dopamine secretion; ureteric bud developmen | |
| GDPD2 | glycerol metabolic process; lipid metabolic process | |
| GDPD3 | lipid metabolic process; glycerol metabolic process | |
| GDPD4 | glycerol metabolic process; lipid metabolic process | |
| GDPD5 | glycerol metabolic process; lipid metabolic process; nervous system development | |
| GEM | GTP catabolic process; small GTPase mediated signal transduction; cell surface receptor signaling pathway; signal transduction; immune response | |
| GEMIN5 | RNA splicing; ncRNA metabolic process; RNA metabolic process; gene expression; protein complex assembly; nuclear mRNA splicing, via spliceosome; spliceosomal snRNP assembly | |
| GEN1 | DNA repair | |
| GET4 | transport; tail-anchored membrane protein insertion into ER membrane | |
| GFAP | regulation of neurotransmitter uptake; long-term synaptic potentiation; Bergmann glial cell differentiation; intermediate filament organization; intermediate filament-based process; neuron projection regeneration; extracellular matrix organization; response to wounding; positive regulation of Schwann cell proliferation; negative regulation of neuron projection development; astrocyte development | |
| GFER | spermatogenesis; cell proliferation; oxidation-reduction process | |
| GFI1B | chromatin modification; positive regulation of granulocyte differentiation; regulation of erythrocyte differentiation; negative regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation; multicellular organismal development; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; cell proliferation; regulation of transcription involved in G1 phase of mitotic cell cycle | |
| GFM1 | GTP catabolic process; mitochondrial translational elongation | |
| GFM2 | mitochondrial translational elongation; ribosome disassembly; mitochondrial translation; GTP catabolic process | |
| GFOD1 | - | |
| GFPT1 | protein N-linked glycosylation via asparagine; endoplasmic reticulum unfolded protein response; post-translational protein modification; cellular protein metabolic process; UDP-N-acetylglucosamine biosynthetic process; metabolic process; activation of signaling protein activity involved in unfolded protein response; glutamine metabolic process; carbohydrate biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; energy reserve metabolic process; fructose 6-phosphate metabolic process | |
| GFPT2 | post-translational protein modification; protein N-linked glycosylation via asparagine; carbohydrate biosynthetic process; metabolic process; fructose 6-phosphate metabolic process; UDP-N-acetylglucosamine biosynthetic process; energy reserve metabolic process; dolichol-linked oligosaccharide biosynthetic process; glutamine metabolic process; cellular protein metabolic process | |
| GFRA1 | cell surface receptor signaling pathway; nervous system development; axon guidance; glial cell-derived neurotrophic factor receptor signaling pathway | |
| GFRA3 | neuron development; sympathetic nervous system development; peripheral nervous system development; signal transduction; neuron migration; nervous system development | |
| GGA1 | intracellular protein transport; vesicle-mediated transport | |
| GGA2 | vesicle-mediated transport; intracellular protein transport | |
| GGA3 | vesicle-mediated transport; intracellular protein transport | |
| GGH | response to ethanol; response to drug; response to insulin stimulus; response to zinc ion; glutamine metabolic process | |
| GGN | cell differentiation; protein localization; spermatogenesis; gamete generation; multicellular organismal development | |
| GGPS1 | isoprenoid biosynthetic process; isoprenoid metabolic process; small molecule metabolic process; cholesterol biosynthetic process | |
| GGT5 | small molecule metabolic process; leukotriene biosynthetic process; metabolic process; inflammatory response; glutathione biosynthetic process; glutathione metabolic process; prostanoid metabolic process; cellular amino acid metabolic process | |
| GGT7 | leukotriene biosynthetic process; glutathione biosynthetic process; glutathione metabolic process | |
| GHDC | - | |
| GHITM | apoptotic process | |
| GHR | valine metabolic process; receptor internalization; taurine metabolic process; insulin-like growth factor receptor signaling pathway; hormone-mediated signaling pathway; JAK-STAT cascade; endocytosis; fatty acid metabolic process; creatine metabolic process; response to food; isoleucine metabolic process; oxaloacetate metabolic process; succinate metabolic process; 2-oxoglutarate metabolic process; citrate metabolic process; allantoin metabolic process; activation of MAPK activity; activation of JAK2 kinase activity; response to cycloheximide; creatinine metabolic process; positive regulation of JAK-STAT cascade; positive regulation of cell differentiation; multicellular organismal metabolic process; neuroprotection; response to peptide hormone stimulus; response to morphine; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of multicellular organism g | |
| GHRH | adenohypophysis development; positive regulation of hormone secretion; positive regulation of circadian sleep/wake cycle, non-REM sleep; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of transcription, DNA-dependent; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of multicellular organism growth; response to food; positive regulation of cAMP biosynthetic process; growth hormone secretion; cAMP-mediated signaling; negative regulation of cardiac muscle cell apoptosis; positive regulation of cell proliferation; cell-cell signaling; elevation of cytosolic calcium ion concentration; activation of adenylate cyclase activity by G-protein signaling pathway; positive regulation of growth hormone secretion | |
| GHRHR | water homeostasis; cAMP-mediated signaling; adenohypophysis development; hormone metabolic process; positive regulation of cAMP biosynthetic process; response to insulin stimulus; cellular response to insulin stimulus; determination of adult lifespan; positive regulation of cell proliferation; lactation; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein coupled receptor signaling pathway; positive regulation of multicellular organism growth; regulation of intracellular steroid hormone receptor signaling pathway; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of hormone secretion; cell maturation; multicellular organismal reproductive process; regulation of protein metabolic process; response to glucocorticoid stimulus; positive regulation of growth hormone secretion; somatotropin secreting cell development; response to estrogen stimulus | |
| GHSR | response to hormone stimulus; regulation of synapse assembly; negative regulation of inflammatory response; decidualization; negative regulation of insulin secretion; positive regulation of fatty acid metabolic process; G-protein coupled receptor signaling pathway; actin polymerization or depolymerization; adult feeding behavior; negative regulation of interleukin-6 biosynthetic process; hormone-mediated signaling pathway; growth hormone secretion; response to food; positive regulation of appetite; negative regulation of interleukin-1 beta production; cellular response to insulin stimulus; positive regulation of multicellular organism growth; negative regulation of tumor necrosis factor biosynthetic process; regulation of hindgut contraction; positive regulation of insulin-like growth factor receptor signaling pathway | |
| GIGYF1 | insulin-like growth factor receptor signaling pathway | |
| GIGYF2 | cell death | |
| GIMAP1 | T cell differentiation; B cell differentiation | |
| GIMAP2 | - | |
| GIMAP6 | - | |
| GIMAP7 | - | |
| GIMAP8 | - | |
| GIN1 | DNA integration | |
| GIP | positive regulation of cAMP-mediated signaling; response to drug; triglyceride homeostasis; positive regulation of glucagon secretion; long-term synaptic potentiation; digestive system development; regulation of insulin secretion; response to axon injury; small molecule metabolic process; response to peptide hormone stimulus; response to amino acid stimulus; response to starvation; positive regulation of insulin secretion; response to organic cyclic compound; positive regulation of glucose transport; response to selenium ion; response to glucose stimulus; response to carbohydrate stimulus; female pregnancy; signal transduction; energy reserve metabolic process | |
| GIPC1 | protein targeting; G-protein coupled receptor signaling pathway; synaptic transmission; glutamate secretion; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of protein stability; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; endothelial cell migration; regulation of synaptic plasticity | |
| GIPC3 | - | |
| GIPR | response to glucose stimulus; elevation of cytosolic calcium ion concentration; response to nutrient; response to axon injury; positive regulation of cAMP biosynthetic process; positive regulation of insulin secretion; response to calcium ion; activation of adenylate cyclase activity; activation of adenylate cyclase activity by G-protein signaling pathway; cell surface receptor signaling pathway; generation of precursor metabolites and energy; desensitization of G-protein coupled receptor protein signaling pathway; response to fatty acid | |
| GIT1 | regulation of G-protein coupled receptor protein signaling pathway; regulation of ARF GTPase activity | |
| GIT2 | regulation of G-protein coupled receptor protein signaling pathway; regulation of ARF GTPase activity | |
| GJA10 | gamete generation; response to light stimulus; detection of light stimulus involved in visual perception; transmembrane transport; synapse assembly; synaptic transmission; cell communication | |
| GJA4 | cell-cell signaling; blood vessel development; transport; calcium ion transport; cell-cell junction assembly; cell communication; response to pain | |
| GJA8 | visual perception; lens development in camera-type eye; transport; cell communication | |
| GJA9 | cell communication | |
| GJB1 | transport; cell-cell signaling; nervous system development; purine ribonucleotide transport; cellular membrane organization; gap junction assembly; protein oligomerization | |
| GJB3 | in utero embryonic development; placenta development; cell communication; sensory perception of sound; skin development | |
| GJB4 | cell communication; sensory perception of smell; olfactory behavior | |
| GJB6 | cell communication; sensory perception of sound; ear morphogenesis | |
| GJB7 | cell communication | |
| GJC1 | cell-cell junction assembly; vasculogenesis; visual perception; transport; synaptic transmission; muscle contraction; cardiac muscle tissue development; cell development; cellular membrane organization; gap junction assembly | |
| GJC2 | transmembrane transport; cell-cell signaling; response to toxin; cell death | |
| GK | carbohydrate metabolic process; triglyceride biosynthetic process; cellular lipid metabolic process; small molecule metabolic process; glycerol-3-phosphate biosynthetic process; glycerol metabolic process; triglyceride metabolic process | |
| GK2 | carbohydrate metabolic process; glycerol metabolic process; glycerol-3-phosphate metabolic process | |
| GKAP1 | signal transduction | |
| GKN1 | positive regulation of cell division; positive regulation of cell proliferation; digestion | |
| GKN2 | - | |
| GLB1 | galactose catabolic process; glycosphingolipid metabolic process; sphingolipid metabolic process; carbohydrate metabolic process; small molecule metabolic process | |
| GLB1L | carbohydrate metabolic process | |
| GLB1L2 | carbohydrate metabolic process | |
| GLCE | heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process | |
| GLDN | multicellular organismal development; nervous system development; cell differentiation | |
| GLG1 | regulation of chondrocyte differentiation; negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; bone morphogenesis | |
| GLI1 | digestive tract morphogenesis; negative regulation of canonical Wnt receptor signaling pathway; osteoblast differentiation; smoothened signaling pathway; multicellular organismal development; positive regulation of cell proliferation; regulation of smoothened signaling pathway; epidermal cell differentiation; positive regulation of DNA replication; positive regulation of smoothened signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter | |
| GLI2 | embryonic digestive tract development; developmental growth; neuron development; branching morphogenesis of a tube; notochord regression; head development; prostatic bud formation; mammary gland duct morphogenesis; smoothened signaling pathway involved in dorsal/ventral neural tube patterning; cellular response to organic cyclic compound; cochlea morphogenesis; spinal cord ventral commissure morphogenesis; specification of segmental identity, maxillary segment; proximal/distal pattern formation; epidermal cell differentiation; regulation of smoothened signaling pathway; positive regulation of cell proliferation; cell proliferation; heart development; hindgut morphogenesis; ventral midline development; axon guidance; pattern specification process; positive regulation of transcription, DNA-dependent; smoothened signaling pathway; apoptotic process; regulation of transcription, DNA-dependent; osteoblast development; morphogenesis of an epithelium; kidney development; in utero embryonic development; osteoblast di | |
| GLI3 | anatomical structure formation involved in morphogenesis; neuron fate commitment; embryonic skeletal system morphogenesis; oligodendrocyte differentiation; inner ear development; palate development; frontal suture morphogenesis; lambdoid suture morphogenesis; sagittal suture morphogenesis; mammary gland specification; smoothened signaling pathway involved in dorsal/ventral neural tube patterning; artery development; anterior semicircular canal development; lateral semicircular canal development; cell differentiation involved in kidney development; thymocyte apoptosis; negative regulation of canonical Wnt receptor signaling pathway; mammary gland development; lateral ganglionic eminence cell proliferation; subpallium development; optic nerve morphogenesis; smoothened signaling pathway involved in ventral spinal cord interneuron specification; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; forebrain dorsal/ventral pattern formation; cerebral cortex radial glia guided | |
| GLIS1 | transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter | |
| GLIS3 | transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter | |
| GLMP | intracellular receptor mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; regulation of RNA biosynthetic process | |
| GLRA1 | positive regulation of acrosome reaction; chloride transport; regulation of inhibitory postsynaptic membrane potential; righting reflex; synaptic transmission, glycinergic; transmembrane transport; negative regulation of transmission of nerve impulse; neuromuscular process controlling posture; regulation of respiratory gaseous exchange; regulation of membrane potential; ion transmembrane transport; adult walking behavior; visual perception; synaptic transmission; neuropeptide signaling pathway; ion transport; regulation of respiratory gaseous exchange by neurological system process; startle response; regulation of action potential; muscle contraction | |
| GLRA3 | synaptic transmission; ion transmembrane transport; transmembrane transport | |
| GLRA4 | ion transport | |
| GLRX5 | hemopoiesis; cell redox homeostasis | |
| GLS2 | cellular amino acid metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; glutamate secretion; cellular amino acid biosynthetic process; neurotransmitter secretion; synaptic transmission; glutamine metabolic process | |
| GLT1D1 | biosynthetic process | |
| GLT8D1 | - | |
| GLT8D2 | - | |
| GLTSCR1L | - | |
| GLUD2 | cellular amino acid metabolic process; glutamate metabolic process; glutamate biosynthetic process; glutamate catabolic process; oxidation-reduction process | |
| GLYAT | xenobiotic metabolic process; acyl-CoA metabolic process; response to toxin; small molecule metabolic process | |
| GLYATL1 | - | |
| GLYCTK | protein phosphorylation | |
| GLYR1 | pentose-phosphate shunt | |
| GMEB2 | transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| GMFB | protein phosphorylation; signal transduction; nervous system development; positive regulation of catalytic activity | |
| GML | negative regulation of cell proliferation; apoptotic process; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | |
| GMNN | organ morphogenesis; negative regulation of DNA replication; negative regulation of cell cycle; mitotic cell cycle; M/G1 transition of mitotic cell cycle; negative regulation of transcription, DNA-dependent; protein complex assembly | |
| GMPPA | dolichol-linked oligosaccharide biosynthetic process; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; GDP-mannose biosynthetic process; biosynthetic process | |
| GNA13 | patterning of blood vessels; in utero embryonic development; GTP catabolic process; cellular component movement; signal transduction; G-protein coupled receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; intracellular protein kinase cascade; activation of phospholipase D activity; regulation of cell migration; platelet activation; cell differentiation; regulation of cell shape; blood coagulation; Rho protein signal transduction | |
| GNAI1 | cell cycle; signal transduction; G-protein coupled receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; synaptic transmission; blood coagulation; cell division; platelet activation; GTP catabolic process | |
| GNAL | response to caffeine; sensory perception of smell; synaptic transmission; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by dopamine receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein coupled receptor signaling pathway; signal transduction; GTP catabolic process; response to amphetamine; cAMP biosynthetic process | |
| GNAO1 | locomotory behavior; negative regulation of calcium ion transport; positive regulation of GTPase activity; response to morphine; response to hydrogen peroxide; response to drug; response to cytokine stimulus; neuron projection development; forebrain development; response to organic cyclic compound; response to organic nitrogen; cellular process; regulation of heart contraction; aging; dopamine receptor signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; muscle contraction; GTP catabolic process | |
| GNAQ | activation of phospholipase C activity; glutamate receptor signaling pathway; heart development; forebrain neuron development; blood coagulation; behavior; post-embryonic development; neuron remodeling; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein coupled receptor signaling pathway; protein ADP-ribosylation; negative regulation of protein kinase activity; GTP catabolic process; regulation of action potential; skeletal system development; regulation of catenin import into nucleus; embryonic digit morphogenesis; positive regulation of GTPase activity; regulation of melanocyte differentiation; developmental pigmentation; protein stabilization; activation of phospholipase C activity by dopamine receptor signaling pathway; platelet activation | |
| GNAS | tissue homeostasis; activation of adenylate cyclase activity; G-protein coupled receptor signaling pathway; water transport; DNA methylation; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; endochondral ossification; embryonic hindlimb morphogenesis; embryonic cranial skeleton morphogenesis; regulation of insulin secretion; cartilage development; transmembrane transport; cellular response to glucagon stimulus; genetic imprinting; post-embryonic development; female pregnancy; activation of adenylate cyclase activity by dopamine receptor signaling pathway; multicellular organism growth; post-embryonic body morphogenesis; response to drug; skin development; small molecule metabolic process; positive regulation of osteoblast differentiation; intracellular transport; protein secretion; behavior; sensory perception of smell; sensory perception of chemical stimulus; blood coagulation; positive regulation of osteoclast differentiation | |
| GNAT2 | elevation of cytosolic calcium ion concentration; detection of light stimulus involved in visual perception; response to stimulus; retinal cone cell development; response to light intensity; rhodopsin mediated phototransduction; detection of visible light; visual perception; phototransduction; GTP catabolic process; G-protein coupled receptor signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; detection of chemical stimulus involved in sensory perception of bitter taste | |
| GNB1 | cellular response to glucagon stimulus; retina development in camera-type eye; sensory perception of taste; small molecule metabolic process; platelet activation; cell proliferation; blood coagulation; synaptic transmission; G-protein coupled acetylcholine receptor signaling pathway; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; signal transduction; GTP catabolic process; energy reserve metabolic process; Ras protein signal transduction | |
| GNB1L | G-protein coupled receptor signaling pathway; social behavior; intracellular signal transduction | |
| GNB2 | GTP catabolic process; cellular response to glucagon stimulus; small molecule metabolic process; synaptic transmission; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; energy reserve metabolic process | |
| GNB3 | cellular response to glucagon stimulus; small molecule metabolic process; regulation of blood pressure; G-protein coupled receptor signaling pathway; GTP catabolic process; energy reserve metabolic process; synaptic transmission | |
| GNB4 | cellular response to glucagon stimulus; small molecule metabolic process; energy reserve metabolic process | |
| GNB5 | G-protein coupled receptor signaling pathway; signal transduction; GTP catabolic process | |
| GNE | lipopolysaccharide biosynthetic process; cell adhesion; UDP-N-acetylglucosamine metabolic process; carbohydrate metabolic process; N-acetylneuraminate metabolic process | |
| GNGT1 | cellular response to hypoxia; eye photoreceptor cell development; G-protein coupled receptor signaling pathway; cardiac muscle cell apoptosis; protein localization; synaptic transmission; signal transduction; GTP catabolic process; phototransduction | |
| GNL2 | GTP catabolic process; ribosome biogenesis | |
| GNL3L | ribosome biogenesis | |
| GNPAT | metabolic process; paranodal junction assembly; ether lipid biosynthetic process; phospholipid biosynthetic process; cellular membrane organization; cerebellum morphogenesis; response to drug; myelination; response to starvation; cellular lipid metabolic process; small molecule metabolic process; response to fatty acid; synapse assembly; response to nutrient | |
| GNPTAB | protein secretion; cell differentiation; carbohydrate phosphorylation | |
| GNS | glycosaminoglycan catabolic process; keratan sulfate catabolic process | |
| GOLGA1 | protein targeting to Golgi | |
| GOLGA2 | Golgi localization; positive regulation of axonogenesis | |
| GOLGA3 | intra-Golgi vesicle-mediated transport | |
| GOLGA4 | protein targeting to Golgi; vesicle-mediated transport; Golgi to plasma membrane protein transport | |
| GOLGA5 | retrograde transport, vesicle recycling within Golgi; Golgi vesicle transport; Golgi organization | |
| GOLGA7B | - | |
| GOLGB1 | Golgi organization | |
| GOLIM4 | transport | |
| GOLM1 | - | |
| GON4L | regulation of transcription, DNA-dependent | |
| GOPC | ER to Golgi vesicle-mediated transport; Golgi to plasma membrane transport; spermatid nucleus differentiation; protein transport; cytoplasmic sequestering of CFTR protein; apical protein localization; regulation of catalytic activity; protein homooligomerization | |
| GORASP1 | mitotic cell cycle; protein transport; M phase of mitotic cell cycle; mitotic prophase; Golgi organization | |
| GORASP2 | organelle organization; Golgi organization | |
| GOSR1 | protein transport; ER to Golgi vesicle-mediated transport; vesicle-mediated transport; retrograde transport, endosome to Golgi; intra-Golgi vesicle-mediated transport | |
| GOT1 | polyamine metabolic process; glutamate metabolic process; cellular amino acid biosynthetic process; biosynthetic process; L-methionine salvage from methylthioadenosine; glutamate catabolic process to aspartate; glutamate catabolic process to 2-oxoglutarate; cellular response to insulin stimulus; cellular nitrogen compound metabolic process; small molecule metabolic process; response to glucocorticoid stimulus; fatty acid homeostasis; aspartate catabolic process; sulfur amino acid metabolic process; carbohydrate metabolic process; glucose metabolic process; gluconeogenesis; 2-oxoglutarate metabolic process; oxaloacetate metabolic process; glycerol biosynthetic process; aspartate metabolic process; aspartate biosynthetic process | |
| GP2 | - | |
| GP5 | negative regulation of platelet activation; platelet activation; blood coagulation, intrinsic pathway; blood coagulation; cell adhesion; cell-matrix adhesion | |
| GP6 | enzyme linked receptor protein signaling pathway; blood coagulation; platelet activation; leukocyte migration | |
| GPA33 | - | |
| GPAA1 | cellular protein metabolic process; post-translational protein modification; attachment of GPI anchor to protein; protein retention in ER lumen; C-terminal protein lipidation; protein complex assembly | |
| GPALPP1 | - | |
| GPAM | metabolic process; negative regulation of activation-induced cell death of T cells; glycerophospholipid metabolic process; acyl-CoA metabolic process; fatty acid metabolic process; interleukin-2 secretion; cellular lipid metabolic process; defense response to virus; fatty acid homeostasis; phospholipid homeostasis; response to activity; regulation of cytokine secretion; positive regulation of multicellular organism growth; response to fructose stimulus; response to glucose stimulus; phospholipid biosynthetic process; positive regulation of activated T cell proliferation; response to nutrient levels; positive regulation of triglyceride biosynthetic process; response to cadmium ion; triglyceride biosynthetic process; small molecule metabolic process; cellular response to insulin stimulus | |
| GPATCH2 | negative regulation of phosphatase activity | |
| GPATCH2L | - | |
| GPATCH4 | - | |
| GPATCH8 | - | |
| GPBP1L1 | regulation of transcription, DNA-dependent | |
| GPC1 | axon guidance | |
| GPC2 | neuron differentiation | |
| GPC3 | anatomical structure morphogenesis; mesenchymal cell proliferation involved in ureteric bud development | |
| GPC4 | cell proliferation; anatomical structure morphogenesis | |
| GPC5 | - | |
| GPC6 | - | |
| GPD1L | carbohydrate metabolic process; glycerol-3-phosphate catabolic process | |
| GPD2 | glycerol-3-phosphate metabolic process; gluconeogenesis; NADH metabolic process; cellular lipid metabolic process; small molecule metabolic process | |
| GPHA2 | - | |
| GPI | angiogenesis; small molecule metabolic process; glycolysis; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process; humoral immune response; hemostasis | |
| GPLD1 | positive regulation of apoptotic process; hematopoietic stem cell migration; positive regulation of cytolysis; phosphatidylcholine metabolic process; positive regulation of membrane protein ectodomain proteolysis; positive regulation of secretion; transepithelial transport; cellular response to calcium ion; cellular response to cholesterol; cellular response to triglyceride; cellular response to pH; hematopoietic stem cell migration to bone marrow; regulation of cellular response to insulin stimulus; positive regulation of endothelial cell migration; ossification; cell migration involved in sprouting angiogenesis; chondrocyte differentiation; complement receptor mediated signaling pathway; GPI anchor release; negative regulation of cell proliferation; insulin receptor signaling pathway; response to glucose stimulus; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of alkaline phosphatase activity; positive regulation of triglyceride biosynthetic p | |
| GPN3 | - | |
| GPNMB | cell adhesion; negative regulation of cell proliferation | |
| GPR1 | G-protein coupled receptor signaling pathway | |
| GPR101 | - | |
| GPR107 | - | |
| GPR108 | - | |
| GPR135 | - | |
| GPR137 | - | |
| GPR137B | - | |
| GPR139 | activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; G-protein coupled receptor signaling pathway; synaptic transmission | |
| GPR142 | - | |
| GPR146 | - | |
| GPR148 | - | |
| GPR149 | - | |
| GPR15 | G-protein coupled receptor signaling pathway | |
| GPR152 | - | |
| GPR153 | - | |
| GPR155 | intracellular signal transduction; transmembrane transport | |
| GPR156 | - | |
| GPR157 | - | |
| GPR158 | - | |
| GPR160 | - | |
| GPR161 | multicellular organismal development | |
| GPR162 | - | |
| GPR17 | G-protein coupled receptor signaling pathway | |
| GPR174 | - | |
| GPR176 | synaptic transmission; G-protein coupled receptor signaling pathway | |
| GPR179 | - | |
| GPR18 | G-protein coupled receptor signaling pathway | |
| GPR180 | - | |
| GPR182 | cell surface receptor signaling pathway; response to hypoxia | |
| GPR20 | G-protein coupled receptor signaling pathway | |
| GPR26 | activation of adenylate cyclase activity by G-protein signaling pathway | |
| GPR27 | G-protein coupled receptor signaling pathway; signal transduction | |
| GPR34 | intracellular protein transport; G-protein coupled receptor signaling pathway | |
| GPR35 | G-protein coupled receptor signaling pathway | |
| GPR37 | G-protein coupled receptor signaling pathway | |
| GPR37L1 | - | |
| GPR39 | G-protein coupled receptor signaling pathway | |
| GPR45 | - | |
| GPR50 | cell-cell signaling; G-protein coupled receptor signaling pathway | |
| GPR55 | G-protein coupled receptor signaling pathway; negative regulation of osteoclast differentiation; bone resorption; positive regulation of Rho protein signal transduction; activation of phospholipase C activity; positive regulation of ERK1 and ERK2 cascade | |
| GPR6 | G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration | |
| GPR61 | - | |
| GPR62 | - | |
| GPR63 | - | |
| GPR65 | immune response; G-protein coupled receptor signaling pathway; multicellular organismal development; response to acidity; positive regulation of cAMP biosynthetic process; actin cytoskeleton reorganization; activation of Rho GTPase activity; positive regulation of stress fiber assembly; apoptotic process | |
| GPR68 | inflammatory response; G-protein coupled receptor signaling pathway | |
| GPR75 | G-protein coupled receptor signaling pathway | |
| GPR78 | activation of adenylate cyclase activity by G-protein signaling pathway | |
| GPR84 | - | |
| GPR85 | signal transduction; G-protein coupled receptor signaling pathway | |
| GPR87 | - | |
| GPRASP1 | - | |
| GPRC5A | signal transduction; G-protein coupled receptor signaling pathway | |
| GPRC5C | G-protein coupled receptor signaling pathway | |
| GPRC5D | - | |
| GPRC6A | response to amino acid stimulus; calcium-mediated signaling | |
| GPRIN1 | neuron projection development | |
| GPRIN3 | - | |
| GPSM1 | cell differentiation; signal transduction; regulation of G-protein coupled receptor protein signaling pathway; multicellular organismal development; nervous system development | |
| GPSM2 | establishment of mitotic spindle orientation; signal transduction; G-protein coupled receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; lung epithelial cell differentiation | |
| GPT | cellular nitrogen compound metabolic process; cellular amino acid biosynthetic process; gluconeogenesis; small molecule metabolic process; nitrogen compound metabolic process; biosynthetic process | |
| GPX3 | response to drug; response to molecule of fungal origin; glutathione metabolic process; response to oxidative stress; female pregnancy; response to selenium ion; response to organic cyclic compound; hydrogen peroxide catabolic process; response to corticosterone stimulus; response to lipid hydroperoxide; protein homotetramerization; oxidation-reduction process | |
| GPX4 | oxidation-reduction process; multicellular organismal development; response to oxidative stress; phospholipid metabolic process | |
| GRAMD1A | - | |
| GRAMD1C | - | |
| GRAMD2 | - | |
| GRAMD4 | apoptotic process | |
| GRASP | protein localization; signal transduction | |
| GRB10 | negative regulation of Wnt receptor signaling pathway; response to insulin stimulus; insulin receptor signaling pathway; negative regulation of phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; signal transduction; negative regulation of glucose import; insulin-like growth factor receptor signaling pathway; positive regulation of phosphorylation; negative regulation of glycogen biosynthetic process; negative regulation of insulin receptor signaling pathway | |
| GRB14 | intracellular signal transduction; leukocyte migration; signal transduction; negative regulation of insulin receptor signaling pathway; blood coagulation | |
| GRB7 | signal transduction; epidermal growth factor receptor signaling pathway; blood coagulation; negative regulation of translation; positive regulation of cell migration; stress granule assembly; leukocyte migration | |
| GREB1 | - | |
| GRHL1 | multicellular organismal development; small molecule metabolic process; cellular lipid metabolic process; regulation of transcription, DNA-dependent | |
| GRHL2 | - | |
| GRHPR | oxidation-reduction process; excretion; metabolic process; cellular nitrogen compound metabolic process; glyoxylate metabolic process; small molecule metabolic process | |
| GRIA1 | ion transport; signal transduction; synaptic transmission; long-term memory; receptor internalization | |
| GRIA2 | ion transport; signal transduction; synaptic transmission | |
| GRIA3 | regulation of receptor recycling; transport; ion transport; glutamate receptor signaling pathway; synaptic transmission; response to lithium ion; response to fungicide | |
| GRIA4 | transport; ion transport; glutamate receptor signaling pathway; synaptic transmission; regulation of synaptic transmission; positive regulation of synaptic transmission, glutamatergic; response to fungicide | |
| GRID1 | ion transport | |
| GRID2 | transport; ion transport; glutamate receptor signaling pathway; synaptic transmission, glutamatergic; regulation of neuron apoptosis; regulation of excitatory postsynaptic membrane potential; prepulse inhibition | |
| GRIK1 | regulation of excitatory postsynaptic membrane potential; ion transport; signal transduction; glutamate receptor signaling pathway; synaptic transmission; nervous system development; central nervous system development; positive regulation of gamma-aminobutyric acid secretion; adult behavior; negative regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, GABAergic; regulation of short-term neuronal synaptic plasticity; behavioral response to pain; regulation of synaptic transmission, glutamatergic; negative regulation of synaptic transmission, glutamatergic; transport; regulation of inhibitory postsynaptic membrane potential | |
| GRIK2 | behavioral fear response; transport; ion transport; cellular calcium ion homeostasis; intracellular protein transport; signal transduction; glutamate receptor signaling pathway; synaptic transmission; regulation of action potential in neuron; induction of programmed cell death in response to chemical stimulus; regulation of membrane potential; receptor clustering; negative regulation of neuron apoptosis; regulation of JNK cascade; regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; regulation of synaptic transmission; positive regulation of synaptic transmission; neuron apoptosis; negative regulation of synaptic transmission, glutamatergic; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential | |
| GRIK3 | ion transport; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; glutamate receptor signaling pathway; G-protein coupled glutamate receptor signaling pathway; synaptic transmission; ionotropic glutamate receptor signaling pathway; regulation of membrane potential; negative regulation of synaptic transmission, glutamatergic | |
| GRIK4 | transport; ion transport; glutamate receptor signaling pathway; synaptic transmission; response to corticosteroid stimulus | |
| GRIN1 | ion transport; cation transport; synaptic transmission; visual learning; ionotropic glutamate receptor signaling pathway; regulation of membrane potential; response to ethanol; positive regulation of transcription from RNA polymerase II promoter; calcium ion homeostasis; regulation of excitatory postsynaptic membrane potential; calcium ion transmembrane transport | |
| GRIN2A | response to carbohydrate stimulus; response to drug; serotonin metabolic process; dopamine metabolic process; response to cocaine; negative regulation of protein catabolic process; directional locomotion; sleep; neurogenesis; cerebral cortex development; hippocampus development; spinal cord development; response to organic cyclic compound; positive regulation of cell death; cellular response to manganese ion; positive regulation of apoptotic process; response to ethanol; regulation of synaptic plasticity; regulation of long-term neuronal synaptic plasticity; rhythmic process; response to calcium ion; response to methylmercury; response to other organism; regulation of sensory perception of pain; regulation of excitatory postsynaptic membrane potential; response to ammonium ion; response to fungicide; cellular response to amino acid stimulus; cellular response to magnesium ion; response to light stimulus; cellular response to lipid; cellular response to growth factor stimulus; cellular response to dsRNA; cellu | |
| GRIN2B | response to mechanical stimulus; response to fungicide; response to carbohydrate stimulus; cellular response to magnesium starvation; positive regulation of cell death; positive regulation of glutamate secretion; hippocampus development; cerebral cortex development; response to magnesium ion; multicellular organismal response to stress; response to cytokine stimulus; response to cocaine; receptor clustering; regulation of MAPK cascade; response to ethanol; regulation of long-term neuronal synaptic plasticity; rhythmic process; positive regulation of synaptic transmission; response to calcium ion; response to methylmercury; response to electrical stimulus; response to other organism; response to growth hormone stimulus; long-term memory; cellular response to organic cyclic compound; cellular response to lipid; cellular response to growth factor stimulus; cellular response to dsRNA; cellular response to manganese ion; cellular response to amino acid stimulus; response to acid; regulation of action potential; re | |
| GRIN2C | transport; ion transport; cation transport; signal transduction; glutamate receptor signaling pathway; synaptic transmission; protein localization; response to wounding; directional locomotion; ion transmembrane transport; negative regulation of protein catabolic process; regulation of membrane potential; neuromuscular process controlling balance; regulation of excitatory postsynaptic membrane potential | |
| GRIN2D | startle response; ion transport; signal transduction; synaptic transmission; adult locomotory behavior; synaptic transmission, glutamatergic; regulation of sensory perception of pain | |
| GRIN3A | prepulse inhibition; rhythmic process; response to ethanol; dendrite development; ion transport; calcium ion transport; signal transduction | |
| GRIN3B | regulation of calcium ion transport; ion transport; synaptic transmission; ionotropic glutamate receptor signaling pathway; protein insertion into membrane; calcium ion transmembrane transport | |
| GRIP1 | positive regulation of transcription, DNA-dependent; intracellular signal transduction; androgen receptor signaling pathway; synaptic transmission | |
| GRIPAP1 | - | |
| GRK4 | receptor internalization; termination of G-protein coupled receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; signal transduction; G-protein coupled receptor internalization | |
| GRK7 | response to stimulus; protein autophosphorylation; signal transduction; visual perception; termination of G-protein coupled receptor signaling pathway | |
| GRM1 | activation of MAPKK activity; regulation of MAPK cascade; calcium-mediated signaling; locomotory behavior; synaptic transmission; G-protein coupled receptor signaling pathway; activation of MAPK activity; regulation of sensory perception of pain; regulation of synaptic transmission, glutamatergic; cellular response to electrical stimulus | |
| GRM2 | synaptic transmission; G-protein coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; glutamate secretion | |
| GRM3 | G-protein coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; regulation of synaptic transmission | |
| GRM4 | activation of MAPK activity; G-protein coupled receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; neurotransmitter secretion; positive regulation of MAPK cascade; neuroprotection | |
| GRM5 | activation of MAPKKK activity; desensitization of G-protein coupled receptor protein signaling pathway; regulation of transcription, DNA-dependent; protein phosphorylation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; learning; locomotory behavior; negative regulation of locomotion; positive regulation of long-term neuronal synaptic plasticity | |
| GRM6 | G-protein coupled glutamate receptor signaling pathway; synaptic transmission; visual perception; locomotory behavior; detection of visible light; response to stimulus; retina development in camera-type eye | |
| GRM7 | conditioned taste aversion; behavioral fear response; negative regulation of adenylate cyclase activity; response to stimulus; synaptic transmission; calcium ion transmembrane transport; sensory perception of sound; sensory perception of smell; short-term memory; negative regulation of glutamate secretion; adult behavior; negative regulation of cAMP biosynthetic process; multicellular organismal response to stress | |
| GRM8 | G-protein coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; visual perception; sensory perception of smell; negative regulation of cAMP biosynthetic process; synaptic transmission, glutamatergic; regulation of neurotransmitter secretion; response to stimulus | |
| GRP | neuropeptide signaling pathway; signal transduction | |
| GRPEL1 | protein folding; protein import into mitochondrial matrix | |
| GRTP1 | - | |
| GRXCR1 | cell redox homeostasis; post-embryonic organ morphogenesis; inner ear development; vestibular receptor cell development; inner ear receptor cell development; inner ear receptor stereocilium organization; auditory receptor cell differentiation; negative regulation of phosphatase activity; sensory perception of sound | |
| GSAP | - | |
| GSDMB | - | |
| GSDMD | - | |
| GSE1 | - | |
| GSG1 | - | |
| GSG1L | - | |
| GSK3A | negative regulation of insulin receptor signaling pathway; negative regulation of glucose import; positive regulation of transcription from RNA polymerase II promoter; positive regulation of heart contraction; positive regulation of protein catabolic process; negative regulation of glycogen biosynthetic process; hypermethylation of CpG island; nerve growth factor receptor signaling pathway; negative regulation of transferase activity; phosphatidylinositol-mediated signaling; positive regulation of peptidyl-serine phosphorylation; cellular response to insulin stimulus; negative regulation of TOR signaling cascade; endoplasmic reticulum unfolded protein response; positive regulation of cAMP biosynthetic process; cell migration; Wnt receptor signaling pathway; negative regulation of UDP-glucose catabolic process; positive regulation of peptidyl-threonine phosphorylation; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; nervous system development; epidermal growth factor re | |
| GSK3B | positive regulation of protein complex assembly; cell differentiation; negative regulation of protein binding; positive regulation of Rac GTPase activity; regulation of microtubule-based process; intracellular signal transduction; negative regulation of apoptotic process; negative regulation of glycogen biosynthetic process; positive regulation of protein catabolic process; positive regulation of protein export from nucleus; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; negative regulation of NFAT protein import into nucleus; canonical Wnt receptor signaling pathway; superior temporal gyrus development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of type B pancreatic cell development; negative regulation of glycogen (starch) synthase activity; negative regulation of protein complex assembly; epithelial to mesenchymal transition; positive regulation of cell-matrix adhesion; carbohydrate metabolic process; glycogen metabolic pro | |
| GSKIP | - | |
| GSS | cellular amino acid metabolic process; glutathione biosynthetic process; xenobiotic metabolic process; nervous system development; response to oxidative stress; aging; response to xenobiotic stimulus; response to nutrient levels; response to cadmium ion; small molecule metabolic process; response to amino acid stimulus; response to tumor necrosis factor | |
| GSTA4 | small molecule metabolic process; metabolic process; xenobiotic metabolic process; glutathione metabolic process | |
| GSTM2 | xenobiotic catabolic process; metabolic process; glutathione metabolic process | |
| GSTO1 | cellular response to arsenic-containing substance; oxidation-reduction process; small molecule metabolic process; xenobiotic catabolic process; L-ascorbic acid biosynthetic process; L-ascorbic acid metabolic process; metabolic process; xenobiotic metabolic process | |
| GSTP1 | response to toxin; response to reactive oxygen species; negative regulation of acute inflammatory response; negative regulation of protein kinase activity; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; response to amino acid stimulus; negative regulation of MAP kinase activity; negative regulation of MAPK cascade; negative regulation of JUN kinase activity; small molecule metabolic process; response to ethanol; negative regulation of fibroblast proliferation; xenobiotic metabolic process; negative regulation of necrotic cell death; regulation of ERK1 and ERK2 cascade; negative regulation of ERK1 and ERK2 cascade; negative regulation of leukocyte proliferation; cellular response to lipopolysaccharide; cellular response to epidermal growth factor stimulus; cellular response to glucocorticoid stimulus; cellular response to cell-matrix adhesion; negative regulation of monocyte chemotactic prote | |
| GSTZ1 | L-phenylalanine catabolic process; tyrosine catabolic process; glutathione metabolic process; aromatic amino acid family metabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| GSX1 | spinal cord association neuron differentiation; neuron fate commitment; positive regulation of transcription from RNA polymerase II promoter; adenohypophysis development; hypothalamus development; multicellular organismal development | |
| GSX2 | multicellular organismal development | |
| GTDC1 | biosynthetic process | |
| GTF2B | viral reproduction; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; interspecies interaction between organisms | |
| GTF2E1 | viral reproduction; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; interspecies interaction between organisms | |
| GTF2E2 | transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; viral reproduction; gene expression; transcription elongation from RNA polymerase II promoter | |
| GTF2F1 | RNA splicing; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA capping; positive regulation of viral transcription; positive regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; viral reproduction; gene expression; response to virus | |
| GTF2F2 | positive regulation of transcription from RNA polymerase II promoter; gene expression; viral reproduction; RNA splicing; mRNA capping; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; nuclear mRNA splicing, via spliceosome; positive regulation of viral transcription | |
| GTF2H3 | nucleotide-excision repair, DNA damage removal; DNA repair; mRNA capping; translation; protein phosphorylation; gene expression; viral reproduction; positive regulation of viral transcription; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; regulation of transcription, DNA-dependent; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; transcription elongation from RNA polymerase II promoter | |
| GTF3C1 | transcription, DNA-dependent; tRNA transcription from RNA polymerase III promoter; 5S class rRNA transcription from RNA polymerase III type 1 promoter; gene expression; tRNA transcription; rRNA transcription; transcription from RNA polymerase III promoter | |
| GTF3C2 | tRNA transcription from RNA polymerase III promoter; 5S class rRNA transcription from RNA polymerase III type 1 promoter; gene expression; transcription from RNA polymerase III promoter; transcription, DNA-dependent | |
| GTF3C4 | tRNA transcription from RNA polymerase III promoter; positive regulation of catalytic activity; 5S class rRNA transcription from RNA polymerase III type 1 promoter; histone acetylation; gene expression; transcription initiation from RNA polymerase III promoter; transcription from RNA polymerase III promoter; transcription, DNA-dependent | |
| GTPBP2 | - | |
| GTPBP4 | negative regulation of DNA replication; protein stabilization; ribosome biogenesis; negative regulation of collagen binding; regulation of cyclin-dependent protein kinase activity; negative regulation of protein ubiquitination; negative regulation of cell migration; negative regulation of cell-cell adhesion; negative regulation of cell proliferation; GTP catabolic process | |
| GTSF1 | - | |
| GUCA1A | response to stimulus; visual perception; signal transduction | |
| GUCA1C | visual perception; signal transduction | |
| GUCD1 | - | |
| GUCY1A2 | blood coagulation; intracellular signal transduction; signal transduction; cGMP biosynthetic process | |
| GUCY1A3 | blood circulation; cGMP biosynthetic process; nitric oxide mediated signal transduction; blood coagulation; intracellular signal transduction | |
| GUCY2C | cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; response to toxin; intracellular signal transduction; regulation of cell proliferation | |
| GUCY2D | response to stimulus; cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; visual perception; intracellular signal transduction | |
| GUCY2F | response to stimulus; intracellular signal transduction; visual perception; receptor guanylyl cyclase signaling pathway; cGMP biosynthetic process | |
| GUF1 | translation | |
| GXYLT1 | O-glycan processing | |
| GYPA | cytoskeletal anchoring at plasma membrane; regulation of response to osmotic stress; interspecies interaction between organisms | |
| GYS1 | carbohydrate metabolic process; glycogen biosynthetic process; glucose metabolic process; heart development; small molecule metabolic process | |
| GYS2 | glycogen biosynthetic process; carbohydrate metabolic process; glucose metabolic process; generation of precursor metabolites and energy; response to glucose stimulus; small molecule metabolic process | |
| GZF1 | negative regulation of transcription from RNA polymerase II promoter; branching involved in ureteric bud morphogenesis; negative regulation of transcription, DNA-dependent | |
| GZMA | apoptotic process; proteolysis involved in cellular protein catabolic process; negative regulation of oxidoreductase activity; negative regulation of DNA binding; positive regulation of apoptotic process; negative regulation of endodeoxyribonuclease activity; cytolysis; immune response; cleavage of lamin | |
| GZMB | apoptotic process; proteolysis; cleavage of lamin; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; cytolysis | |
| H1FNT | sperm chromatin condensation; chromosome condensation; multicellular organismal development; spermatogenesis; spermatid nucleus elongation; cell differentiation | |
| H1FOO | meiosis; nucleosome assembly | |
| H6PD | glucose metabolic process; carbohydrate metabolic process; NADP metabolic process; pentose-phosphate shunt | |
| HAAO | neuron homeostasis; response to cadmium ion; small molecule metabolic process; cellular nitrogen compound metabolic process; quinolinate biosynthetic process; tryptophan catabolic process; response to zinc ion; pyridine nucleotide biosynthetic process | |
| HABP2 | proteolysis; cell adhesion | |
| HACD4 | fatty acid biosynthetic process | |
| HACE1 | cellular membrane fusion; Rac protein signal transduction; regulation of cell migration; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein ubiquitination; protein modification process; regulation of transcription, DNA-dependent; cell cycle; Golgi organization; protein K48-linked ubiquitination | |
| HADH | fatty acid beta-oxidation; negative regulation of insulin secretion; small molecule metabolic process; cellular lipid metabolic process; response to drug; response to insulin stimulus; response to activity; response to hormone stimulus; fatty acid metabolic process | |
| HADHA | small molecule metabolic process; response to drug; response to insulin stimulus; fatty acid beta-oxidation; fatty acid metabolic process; cellular lipid metabolic process | |
| HADHB | fatty acid metabolic process; fatty acid beta-oxidation; cellular lipid metabolic process; small molecule metabolic process; oxidation-reduction process | |
| HAMP | defense response to fungus; defense response to bacterium; killing of cells of other organism; immune response; cellular iron ion homeostasis | |
| HAND1 | negative regulation of transcription from RNA polymerase II promoter; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; cardiac right ventricle formation; positive regulation of transcription from RNA polymerase II promoter; heart looping; cardiac left ventricle formation; ventricular cardiac muscle tissue morphogenesis; odontogenesis of dentin-containing tooth; embryonic heart tube development; heart development; blastocyst development; multicellular organismal development; mesenchyme development; cartilage morphogenesis; transcription from RNA polymerase II promoter; trophectodermal cell differentiation; mesoderm formation; angiogenesis; cardiac septum morphogenesis; trophoblast giant cell differentiation | |
| HAO1 | fatty acid alpha-oxidation; glyoxylate metabolic process; glycolate catabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; response to oxidative stress | |
| HAP1 | synaptic transmission; protein localization; brain development | |
| HAPLN1 | cell adhesion | |
| HAPLN3 | cell adhesion | |
| HAPLN4 | cell adhesion | |
| HARBI1 | - | |
| HARS2 | tRNA aminoacylation for protein translation; histidyl-tRNA aminoacylation; gene expression; translation | |
| HAS2 | hyaluronan biosynthetic process; positive regulation of urine volume; renal water absorption | |
| HAS3 | positive regulation of transcription, DNA-dependent; carbohydrate metabolic process; hyaluronan biosynthetic process | |
| HAUS3 | cell cycle; mitosis; spindle assembly; centrosome organization; cell division | |
| HAUS4 | cell cycle; mitosis; spindle assembly; centrosome organization; cell division | |
| HAUS7 | cell division; centrosome organization; cell cycle; mitosis; spindle assembly | |
| HAVCR1 | interspecies interaction between organisms | |
| HAVCR2 | - | |
| HAX1 | - | |
| HBS1L | translation; signal transduction | |
| HCAR1 | response to estradiol stimulus | |
| HCFC1 | positive regulation of cell cycle; interspecies interaction between organisms; protein stabilization; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H4-K8 acetylation; reactivation of latent virus; positive regulation of gene expression; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; regulation of protein complex assembly | |
| HCK | positive regulation of actin filament polymerization; cytokine-mediated signaling pathway; peptidyl-tyrosine phosphorylation; viral reproduction; regulation of cell shape; positive regulation of cell proliferation; mesoderm development; integrin-mediated signaling pathway; cell adhesion; exocytosis; protein phosphorylation; innate immune response-activating signal transduction; leukocyte migration involved in immune response; negative regulation of apoptotic process; regulation of phagocytosis; defense response to Gram-positive bacterium; regulation of sequence-specific DNA binding transcription factor activity; lipopolysaccharide-mediated signaling pathway; interferon-gamma-mediated signaling pathway; regulation of podosome assembly; positive regulation of actin cytoskeleton reorganization; regulation of inflammatory response; regulation of defense response to virus by virus; protein autophosphorylation; respiratory burst after phagocytosis; innate immune response; interspecies interaction between organisms; | |
| HCLS1 | positive regulation of tyrosine phosphorylation of STAT protein; intracellular signal transduction; erythrocyte differentiation; response to hormone stimulus; positive regulation of cell proliferation; regulation of transcription, DNA-dependent | |
| HCN1 | ion transport; potassium ion transport; synaptic transmission; retinal cone cell development; transmembrane transport; potassium ion transmembrane transport; apical protein localization | |
| HCN3 | ion transport; transmembrane transport; synaptic transmission; potassium ion transport | |
| HCRTR1 | feeding behavior; synaptic transmission; neuropeptide signaling pathway | |
| HCRTR2 | activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; neuropeptide signaling pathway; synaptic transmission; feeding behavior | |
| HCST | regulation of immune response | |
| HDAC1 | negative regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; chromatin remodeling; regulation of transcription, DNA-dependent; protein deacetylation; anti-apoptosis; blood coagulation; epidermal cell differentiation; histone H4 deacetylation; histone H3 deacetylation; fungiform papilla formation; eyelid development in camera-type eye; hair follicle placode formation; negative regulation of androgen receptor signaling pathway; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cell cycle; interspecies interaction between organisms; negative regulation by host of viral transcription; negative regulation of apoptotic process; embryonic digit morphogenesis; odontogenesis of dentin-containing tooth; histone deacetylation; chromatin modification; positive regulation of receptor biosynthetic pro | |
| HDAC10 | negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; histone deacetylation; chromatin modification; oligodendrocyte development; protein deacetylation; regulation of transcription, DNA-dependent | |
| HDAC2 | negative regulation of transcription from RNA polymerase II promoter; chromatin remodeling; blood coagulation; fungiform papilla formation; eyelid development in camera-type eye; hair follicle placode formation; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of proteolysis; negative regulation of cell cycle; negative regulation of MHC class II biosynthetic process; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of apoptotic process; embryonic digit morphogenesis; odontogenesis of dentin-containing tooth; positive regulation of collagen biosynthetic process; histone deacetylation; dendrite development; negative regulation of neuron projection development; positive regulation of receptor biosynthetic process; epidermal cell differentiation; positive regulation o | |
| HDAC4 | negative regulation of transcription from RNA polymerase II promoter; B cell differentiation; chromatin modification; histone deacetylation; positive regulation of protein sumoylation; cardiac muscle hypertrophy in response to stress; response to denervation involved in regulation of muscle adaptation; regulation of cardiac muscle contraction by calcium ion signaling; nervous system development; positive regulation of cell proliferation; negative regulation of cell proliferation; negative regulation of myotube differentiation; skeletal system development; histone H4 deacetylation; histone H3 deacetylation; response to interleukin-1; chromatin remodeling; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of skeletal muscle fiber development; osteoblast development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; inflammatory response; negat | |
| HDAC5 | chromatin remodeling; histone deacetylation; chromatin organization; negative regulation of transcription from RNA polymerase II promoter; regulation of protein binding; negative regulation of transcription, DNA-dependent; B cell differentiation; chromatin silencing; inflammatory response; regulation of myotube differentiation; negative regulation of myotube differentiation; B cell activation; cellular response to insulin stimulus; chromatin modification; negative regulation of cell migration involved in sprouting angiogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity | |
| HDAC6 | cellular response to hydrogen peroxide; tubulin deacetylation; regulation of receptor activity; peptidyl-lysine deacetylation; lysosome localization; histone deacetylation; chromatin modification; macroautophagy; positive regulation of receptor biosynthetic process; negative regulation of hydrogen peroxide metabolic process; positive regulation of epithelial cell migration; cellular response to misfolded protein; response to organic substance; positive regulation of signal transduction; response to toxin; negative regulation of microtubule depolymerization; intracellular protein transport; misfolded or incompletely synthesized protein catabolic process; protein deacetylation; protein polyubiquitination; positive regulation of apoptotic process; positive regulation of chaperone-mediated protein complex assembly; response to growth factor stimulus; Hsp90 deacetylation; polyubiquitinated misfolded protein transport; aggresome assembly; regulation of androgen receptor signaling pathway; regulation of microtubule- | |
| HDC | histamine metabolic process; histidine metabolic process; histidine catabolic process; cellular nitrogen compound metabolic process; catecholamine biosynthetic process; small molecule metabolic process; cellular amino acid metabolic process | |
| HDGF | regulation of transcription, DNA-dependent; activation of signaling protein activity involved in unfolded protein response; signal transduction; cell proliferation; cellular process; endoplasmic reticulum unfolded protein response | |
| HDGFRP2 | - | |
| HDGFRP3 | - | |
| HDLBP | transport; cholesterol metabolic process; steroid metabolic process; lipid transport | |
| HDX | - | |
| HEATR1 | rRNA processing | |
| HEATR3 | - | |
| HEATR4 | - | |
| HEATR5B | - | |
| HEATR6 | - | |
| HECA | respiratory tube development; multicellular organismal development | |
| HECTD2 | protein modification process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| HECTD3 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein ubiquitination; proteasomal ubiquitin-dependent protein catabolic process; protein modification process | |
| HECW1 | protein modification process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| HECW2 | protein modification process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| HELB | DNA replication, synthesis of RNA primer; DNA replication | |
| HELQ | - | |
| HELT | central nervous system development; negative regulation of transcription from RNA polymerase II promoter; suckling behavior; post-embryonic development; multicellular organismal aging; GABAergic neuron differentiation in basal ganglia; neuron differentiation; multicellular organism growth | |
| HELZ | - | |
| HELZ2 | - | |
| HEMGN | regulation of osteoblast differentiation; cell differentiation; multicellular organismal development | |
| HEMK1 | DNA methylation | |
| HEPACAM | regulation of growth; cell adhesion; cell cycle arrest; cell cycle | |
| HEPACAM2 | - | |
| HEPH | copper ion transport; ion transport; cellular iron ion homeostasis; erythrocyte differentiation; transmembrane transport | |
| HERC2 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process; intracellular protein transport; protein modification process; spermatogenesis; DNA repair; protein ubiquitination | |
| HERC3 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process | |
| HERC5 | regulation of defense response to virus; innate immune response; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of type I interferon production; ISG15-protein conjugation; cytokine-mediated signaling pathway; response to virus; regulation of cyclin-dependent protein kinase activity | |
| HERPUD1 | response to unfolded protein; cellular calcium ion homeostasis; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; endoplasmic reticulum unfolded protein response; activation of signaling protein activity involved in unfolded protein response; response to stress | |
| HERPUD2 | response to unfolded protein; spermatogenesis | |
| HES1 | regulation of secondary heart field cardioblast proliferation; lung development; adenohypophysis development; neural tube development; forebrain radial glial cell differentiation; hindbrain morphogenesis; negative regulation of pro-B cell differentiation; negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; liver development; outflow tract morphogenesis; trochlear nerve development; ventricular septum development; protein complex assembly; cell adhesion; Notch signaling pathway; smoothened signaling pathway; STAT protein import into nucleus; pattern specification process; nervous system development; positive regulation of cell proliferation; cell migration; telencephalon development; midbrain-hindbrain boundary morphogenesis; oculomotor nerve development; S-shaped body morphogenesis; regulation of neurogenesis; pharyngeal system development; regulation of timing of neuron differentiation; negative regulation of glial cell proliferation; ureteric bud morphogenes | |
| HES5 | brain development; central nervous system myelination; glial cell fate commitment; telencephalon development; neural tube development; positive regulation of cell proliferation; oligodendrocyte development; multicellular organismal development; smoothened signaling pathway; Notch signaling pathway; cell adhesion; negative regulation of transcription from RNA polymerase II promoter; chondrocyte differentiation; protein complex assembly; astrocyte differentiation; metanephric nephron tubule morphogenesis; specification of loop of Henle identity; S-shaped body morphogenesis; cartilage development; regulation of neurogenesis; auditory receptor cell fate determination; camera-type eye development; negative regulation of oligodendrocyte differentiation; negative regulation of astrocyte differentiation; comma-shaped body morphogenesis; positive regulation of smooth muscle cell proliferation; cell maturation; positive regulation of JAK-STAT cascade; positive regulation of transcription from RNA polymerase II promoter | |
| HEXDC | carbohydrate metabolic process | |
| HEXIM2 | negative regulation of transcription from RNA polymerase II promoter; negative regulation of cyclin-dependent protein kinase activity; negative regulation of transcription, DNA-dependent | |
| HEYL | epithelial to mesenchymal transition involved in endocardial cushion formation; Notch signaling pathway; multicellular organismal development; glomerulus development; positive regulation of neuron differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of androgen receptor signaling pathway; cellular response to BMP stimulus; proximal tubule development; negative regulation of androgen receptor activity | |
| HFE2 | axon guidance | |
| HFM1 | - | |
| HGD | cellular amino acid metabolic process; L-phenylalanine catabolic process; tyrosine catabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| HGF | activation of MAPK activity; cell chemotaxis; myoblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; hepatocyte growth factor receptor signaling pathway; cell morphogenesis; cellular response to hepatocyte growth factor stimulus; organ regeneration; platelet activation; blood coagulation; mitosis; anti-apoptosis; proteolysis; liver development; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; positive regulation of DNA biosynthetic process; platelet degranulation; epithelial to mesenchymal transition | |
| HGS | negative regulation of JAK-STAT cascade; regulation of protein catabolic process; negative regulation of epidermal growth factor receptor signaling pathway; endosome transport; cellular membrane organization; endosome to lysosome transport; negative regulation of cell proliferation; epidermal growth factor receptor signaling pathway; signal transduction; intracellular protein transport | |
| HHAT | multicellular organismal development | |
| HHATL | negative regulation of N-terminal protein palmitoylation | |
| HHIP | carbohydrate metabolic process; epithelial tube branching involved in lung morphogenesis; neuroblast proliferation; dorsal/ventral pattern formation; skeletal system morphogenesis; negative regulation of smoothened signaling pathway; regulation of fibroblast growth factor receptor signaling pathway; negative regulation of signal transduction | |
| HHIPL2 | carbohydrate metabolic process | |
| HHLA3 | - | |
| HIBADH | branched chain family amino acid catabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; valine metabolic process; pentose-phosphate shunt | |
| HIC2 | negative regulation of transcription, DNA-dependent | |
| HIF1A | embryonic placenta development; B-1 B cell homeostasis; negative regulation of growth; cellular response to insulin stimulus; regulation of transforming growth factor beta2 production; collagen metabolic process; embryonic hemopoiesis; hemoglobin biosynthetic process; glucose homeostasis; mRNA transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; positive regulation of erythrocyte differentiation; positive regulation of angiogenesis; positive regulation of glycolysis; positive regulation of transcription, DNA-dependent; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; muscle cell homeostasis; positive regulation of hormone biosynthetic process; positive regulation of smooth muscle cell proliferation; regulation of catalytic activity; positive regulation of nitric-oxide synthase activity; cartilage development; elastin metabolic process; positive regu | |
| HIF1AN | peptidyl-asparagine hydroxylation; regulation of transcription, DNA-dependent; oxidation-reduction process | |
| HIF3A | response to hypoxia; positive regulation of transcription from RNA polymerase II promoter | |
| HINFP | positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; myoblast differentiation; establishment of protein localization; negative regulation of gene expression; DNA damage checkpoint; positive regulation of gene expression; G1/S transition of mitotic cell cycle; DNA repair; regulation of gene expression; regulation of transcription, DNA-dependent; regulation of transcription involved in G1/S phase of mitotic cell cycle; in utero embryonic development | |
| HINT2 | steroid biosynthetic process; apoptotic process | |
| HIP1 | regulation of apoptotic process; regulation of transcription, DNA-dependent; endocytosis; apoptotic process; induction of apoptosis; cell differentiation; positive regulation of receptor-mediated endocytosis; clathrin coat assembly; cell death; activation of cysteine-type endopeptidase activity involved in apoptotic process | |
| HIP1R | receptor-mediated endocytosis | |
| HIPK1 | definitive hemopoiesis; eye development; positive regulation of angiogenesis; regulation of tumor necrosis factor-mediated signaling pathway; apoptotic process; regulation of transcription, DNA-dependent | |
| HIPK3 | negative regulation of JUN kinase activity; regulation of transcription, DNA-dependent; protein phosphorylation; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; mRNA transcription; apoptotic process; anti-apoptosis | |
| HIPK4 | - | |
| HIRA | chromatin modification; anatomical structure morphogenesis; regulation of transcription from RNA polymerase II promoter; gastrulation | |
| HIRIP3 | chromatin assembly or disassembly | |
| HIST1H1B | nucleosome assembly | |
| HIST1H1C | nucleosome positioning; nucleosome assembly | |
| HIST1H1T | nucleosome assembly; multicellular organismal development; binding of sperm to zona pellucida; cell differentiation; sperm motility; spermatogenesis | |
| HIST1H2AD | nucleosome assembly | |
| HIST1H2AG | nucleosome assembly | |
| HIST1H2AK | nucleosome assembly | |
| HIST1H2AM | - | |
| HIST1H2BB | nucleosome assembly | |
| HIST1H2BD | nucleosome assembly | |
| HIST1H2BI | - | |
| HIST1H3A | - | |
| HIST1H3C | - | |
| HIST1H3I | - | |
| HIST1H3J | - | |
| HIST1H4F | - | |
| HIST1H4G | nucleosome assembly | |
| HIST1H4L | - | |
| HIST2H2AB | nucleosome assembly | |
| HIST3H3 | telomere maintenance; nucleosome assembly | |
| HIVEP1 | negative regulation of transcription from RNA polymerase II promoter | |
| HIVEP2 | regulation of transcription, DNA-dependent | |
| HIVEP3 | positive regulation of transcription, DNA-dependent | |
| HJURP | nucleosome assembly; regulation of DNA binding; CenH3-containing nucleosome assembly at centromere; regulation of protein complex assembly; centromeric core chromatin assembly; chromosome segregation; cell cycle | |
| HK2 | lactation; apoptotic mitochondrial changes; glycolysis; glucose metabolic process; carbohydrate metabolic process; regulation of glucose import; small molecule metabolic process; glucose transport; hexose transport; carbohydrate phosphorylation; transmembrane transport | |
| HKDC1 | carbohydrate metabolic process; glycolysis | |
| HKR1 | multicellular organismal development; regulation of transcription, DNA-dependent | |
| HLA-DQB1 | positive regulation of T-helper 1 type immune response; B cell affinity maturation; cellular response to interferon-gamma; interferon-gamma-mediated signaling pathway; T cell receptor signaling pathway; antigen processing and presentation of peptide antigen; positive regulation of alpha-beta T cell activation; T cell costimulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokine-mediated signaling pathway; immune response; positive regulation of antigen processing and presentation; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | |
| HLCS | histone biotinylation; response to biotin; histone modification; protein biotinylation; cell proliferation | |
| HLF | rhythmic process; transcription from RNA polymerase II promoter; multicellular organismal development | |
| HLTF | regulation of transcription from RNA polymerase II promoter; chromatin modification; regulation of transcription, DNA-dependent | |
| HLX | skeletal muscle tissue development; positive regulation of cell proliferation; cell differentiation; positive regulation of T-helper 1 cell differentiation; negative regulation of T-helper 2 cell differentiation; positive regulation of organ growth; enteric nervous system development; embryonic digestive tract morphogenesis; liver development; multicellular organismal development | |
| HM13 | membrane protein proteolysis | |
| HMBOX1 | negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent | |
| HMCN1 | visual perception; response to stimulus | |
| HMG20A | chromatin modification; chromatin organization; regulation of transcription, DNA-dependent | |
| HMGCLL1 | - | |
| HMGCR | small molecule metabolic process; cholesterol biosynthetic process; isoprenoid biosynthetic process; germ cell migration; gonad development; coenzyme A metabolic process; cellular lipid metabolic process | |
| HMGCS1 | response to acid; response to gonadotropin stimulus; cellular response to organic cyclic compound; cellular response to cholesterol; cellular response to follicle-stimulating hormone stimulus; response to lipoprotein stimulus; response to tellurium ion; small molecule metabolic process; liver development; lipid metabolic process; cellular lipid metabolic process; response to drug; response to vitamin E; response to purine-containing compound; response to organic nitrogen; response to low light intensity stimulus; male gonad development; cholesterol biosynthetic process; brain development; isoprenoid biosynthetic process | |
| HMGCS2 | response to nutrient; midgut development; response to temperature stimulus; isoprenoid biosynthetic process; response to growth hormone stimulus; brain development; cholesterol biosynthetic process; liver development; kidney development; response to cAMP; response to prostaglandin F stimulus; response to linoleic acid; cellular response to lipopolysaccharide; cellular response to amino acid stimulus; cellular response to glucocorticoid stimulus; cellular response to fatty acid; cellular response to organic cyclic compound; ketone body biosynthetic process; cellular ketone body metabolic process; response to ethanol; small molecule metabolic process; cellular lipid metabolic process; response to starvation; response to drug; response to monosaccharide stimulus; response to triglyceride; response to glucagon stimulus; response to testosterone stimulus; multicellular organismal response to stress; cellular response to hormone stimulus; cellular response to insulin stimulus; lung development; response to metal io | |
| HMGN3 | positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; chromatin modification; regulation of insulin secretion involved in cellular response to glucose stimulus | |
| HMGN4 | - | |
| HMGN5 | positive regulation of transcription, DNA-dependent; chromatin modification; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| HMGXB4 | negative regulation of Wnt receptor signaling pathway; endosome to lysosome transport | |
| HMHA1 | small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction | |
| HMOX1 | positive regulation of anti-apoptosis; negative regulation of DNA binding; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of neuron apoptosis; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; response to estrogen stimulus; erythrocyte homeostasis; small molecule metabolic process; positive regulation of chemokine biosynthetic process; regulation of angiogenesis; positive regulation of angiogenesis; positive regulation of vasodilation; positive regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell proliferation; response to stimulus; regulation of sequence-specific DNA binding transcription factor activity; protein homooligomerization; iron ion homeostasis; transmembrane transport; cellular response to hypoxia; positive regulation of I-kappaB kinase/NF-kappaB cascade; porphyrin-containing compound metabolic process; negative regulation of mast cell degranulation; angiogenesis | |
| HMX2 | inner ear morphogenesis; cell differentiation; positive regulation of cell proliferation; brain development; nervous system development; multicellular organismal development | |
| HN1L | - | |
| HNF1A | embryonic limb morphogenesis; regulation of Wnt receptor signaling pathway; insulin secretion; fatty acid transport; bile acid and bile salt transport; response to glucose stimulus; cholesterol metabolic process; protein localization; response to oxidative stress; heme biosynthetic process; bile acid biosynthetic process; fatty acid biosynthetic process; reproductive structure development; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; placenta development; liver development; blastocyst development; regulation of pronephros size; endocrine pancreas development; SMAD protein signal transduction; positive regulation of transcription initiation from RNA polymerase II promoter; regulation of insulin secretion; paraxial mesoderm formation; regulation of hormone secretion; glucose import; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; bone resorption; reverse cholesterol transport; glucose homeostasis; renal glucose absor | |
| HNF1B | positive regulation of transcription from RNA polymerase II promoter; embryonic digestive tract morphogenesis; branching morphogenesis of a tube; pronephros development; genitalia development; hindbrain development; epithelial cell proliferation; positive regulation of transcription initiation from RNA polymerase II promoter; epithelium development; ureteric bud elongation; hepatoblast differentiation; regulation of branch elongation involved in ureteric bud branching; mesonephric duct development; mesonephric duct formation; negative regulation of apoptotic process; negative regulation of transcription from RNA polymerase II promoter; kidney development; inner cell mass cell differentiation; endoderm development; response to glucose stimulus; anterior/posterior pattern specification; insulin secretion; regulation of Wnt receptor signaling pathway; endocrine pancreas development; regulation of pronephros size; pronephric nephron tubule development; regulation of endodermal cell fate specification; positive re | |
| HNF4A | negative regulation of sequence-specific DNA binding transcription factor activity; endocrine pancreas development; signal transduction involved in regulation of gene expression; cell differentiation; negative regulation of cell growth; positive regulation of transcription, DNA-dependent; glucose homeostasis; negative regulation of tyrosine phosphorylation of Stat5 protein; response to drug; negative regulation of protein import into nucleus, translocation; regulation of microvillus assembly; cell-cell junction organization; positive regulation of gluconeogenesis; positive regulation of fatty acid biosynthetic process; negative regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; negative regulation of peptidyl-tyrosine phosphorylation; regulation of insulin secretion; response to cAMP; lipid homeostasis; phospholipid homeostasis; SMAD protein signal transduction; regulation of growth hormone receptor signaling pathway; triglyceride homeostasis; positive regu | |
| HNF4G | regulation of transcription from RNA polymerase II promoter; gene expression; endocrine pancreas development; positive regulation of transcription, DNA-dependent | |
| HNMT | respiratory gaseous exchange; brain development; hyperosmotic response; response to stress; response to tumor cell; response to cocaine; response to glucocorticoid stimulus; response to interleukin-1; response to amine stimulus | |
| HNRNPA2B1 | RNA splicing; nuclear mRNA splicing, via spliceosome; mRNA processing; gene expression; RNA transport | |
| HNRNPA3 | gene expression; nuclear mRNA splicing, via spliceosome; RNA splicing; mRNA transport | |
| HNRNPAB | epithelial to mesenchymal transition; positive regulation of transcription, DNA-dependent | |
| HNRNPC | nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression | |
| HNRNPD | RNA metabolic process; gene expression; RNA splicing; RNA catabolic process; RNA processing; regulation of transcription, DNA-dependent; nuclear mRNA splicing, via spliceosome; mRNA stabilization; positive regulation of transcription, DNA-dependent; mRNA metabolic process | |
| HNRNPDL | - | |
| HNRNPF | regulation of RNA splicing; gene expression; RNA splicing; RNA processing; nuclear mRNA splicing, via spliceosome | |
| HNRNPH3 | RNA processing; RNA splicing; nuclear mRNA splicing, via spliceosome | |
| HNRNPM | RNA splicing; gene expression; nuclear mRNA splicing, via spliceosome; alternative nuclear mRNA splicing, via spliceosome | |
| HNRNPR | gene expression; RNA splicing; mRNA processing; nuclear mRNA splicing, via spliceosome | |
| HNRNPUL1 | nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; RNA processing; RNA splicing; response to virus; gene expression | |
| HNRNPUL2 | - | |
| HOMER1 | activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; positive regulation of signal transduction; response to calcium ion; regulation of store-operated calcium entry; regulation of cation channel activity | |
| HOOK1 | early endosome to late endosome transport; spermatid development; cell differentiation; protein transport; microtubule cytoskeleton organization; endosome organization; lysosome organization; multicellular organismal development; spermatogenesis; endosome to lysosome transport | |
| HOOK2 | endosome organization; endocytosis; microtubule cytoskeleton organization; lysosome organization; protein transport; early endosome to late endosome transport; endosome to lysosome transport | |
| HOOK3 | microtubule anchoring; endosome organization; lysosome organization; endosome to lysosome transport; protein transport; interkinetic nuclear migration; cytoplasmic microtubule organization; microtubule anchoring at centrosome; protein localization to centrosome; Golgi localization; negative regulation of neurogenesis; early endosome to late endosome transport | |
| HOPX | multicellular organismal development; negative regulation of cell differentiation; trophectodermal cell differentiation | |
| HOXA11 | branching involved in ureteric bud morphogenesis; cartilage development involved in endochondral bone morphogenesis; developmental growth; positive regulation of transcription, DNA-dependent; skeletal system development; embryonic digit morphogenesis; positive regulation of chondrocyte differentiation; embryonic limb morphogenesis; positive regulation of cell development; proximal/distal pattern formation; dorsal/ventral pattern formation; anterior/posterior pattern specification; anatomical structure morphogenesis; mesodermal cell fate specification; multicellular organismal development; organ induction; metanephros development | |
| HOXA2 | positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron differentiation; middle ear morphogenesis; brain segmentation; rhombomere 3 morphogenesis; rhombomere 2 development; dorsal/ventral pattern formation; anterior/posterior pattern specification; motor axon guidance; embryonic skeletal system morphogenesis; embryonic viscerocranium morphogenesis; osteoblast development; cell fate determination; negative regulation of transcription from RNA polymerase II promoter; segment specification | |
| HOXA3 | thymus development; parathyroid gland development; cartilage development; embryonic skeletal system morphogenesis; organ formation; thyroid gland development; glossopharyngeal nerve morphogenesis; specification of organ position; anterior/posterior pattern specification; positive regulation of cell proliferation; multicellular organismal development; angiogenesis; blood vessel remodeling | |
| HOXA4 | anatomical structure morphogenesis; multicellular organismal development | |
| HOXA5 | anterior/posterior pattern specification; embryonic skeletal system morphogenesis; positive regulation of receptor biosynthetic process; cell migration; negative regulation of angiogenesis; thyroid gland development; regulation of mammary gland epithelial cell proliferation; multicellular organism growth; positive regulation of apoptotic process; positive regulation of myeloid cell differentiation; negative regulation of erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; lung alveolus development; pattern specification process; respiratory system process; morphogenesis of an epithelium; cell-cell signaling involved in mammary gland development; mammary gland alveolus development; mammary gland epithelial cell differentiation; mesenchymal-epithelial cell signaling; intestinal epithelial cell maturation; trachea cartilage morphogenesis; lung-associated mesenchyme development; lung goblet cell differentiation; epithelial tube branching involved in lung morphogenesi | |
| HOXA6 | embryonic skeletal system morphogenesis; anterior/posterior pattern specification; multicellular organismal development | |
| HOXA9 | proximal/distal pattern formation; mammary gland development; embryonic forelimb morphogenesis; embryonic skeletal system development; definitive hemopoiesis; anterior/posterior pattern specification; multicellular organismal development | |
| HOXB1 | pattern specification process; embryonic skeletal system morphogenesis; multicellular organismal development; regulation of transcription, DNA-dependent; anatomical structure formation involved in morphogenesis; positive regulation of transcription from RNA polymerase II promoter; facial nucleus development; facial nerve structural organization; rhombomere 5 development; rhombomere 4 development; anterior/posterior pattern specification | |
| HOXB2 | neural nucleus development; embryonic skeletal system morphogenesis; rhombomere 4 development; rhombomere 3 development; dorsal/ventral pattern formation; facial nerve structural organization; anterior/posterior pattern specification; blood circulation; multicellular organismal development; morphogenesis of an epithelial sheet | |
| HOXB3 | thyroid gland development; glossopharyngeal nerve morphogenesis; anterior/posterior pattern specification; multicellular organismal development; angiogenesis; definitive hemopoiesis; cartilage development; embryonic skeletal system morphogenesis | |
| HOXB7 | multicellular organismal development; embryonic skeletal system morphogenesis; positive regulation of branching involved in ureteric bud morphogenesis; myeloid cell differentiation; anterior/posterior pattern specification; regulation of transcription, DNA-dependent | |
| HOXB8 | adult locomotory behavior; anterior/posterior pattern specification; sensory perception of pain; dorsal spinal cord development; embryonic skeletal system morphogenesis; grooming behavior; multicellular organismal development; regulation of transcription, DNA-dependent | |
| HOXC11 | endoderm development; multicellular organismal development | |
| HOXC9 | multicellular organismal development | |
| HOXD1 | multicellular organismal development; embryonic skeletal system development | |
| HOXD10 | forelimb morphogenesis; hindlimb morphogenesis; positive regulation of transcription from RNA polymerase II promoter; embryonic skeletal system morphogenesis; peripheral nervous system neuron development; neuromuscular process; embryonic limb morphogenesis; spinal cord motor neuron cell fate specification; proximal/distal pattern formation; anterior/posterior pattern specification; adult locomotory behavior; skeletal muscle tissue development; multicellular organismal development; skeletal system development | |
| HOXD11 | positive regulation of cell development; skeletal system development; metanephros development; branching involved in ureteric bud morphogenesis; organ induction; regulation of transcription, DNA-dependent; pattern specification process; proximal/distal pattern formation; anterior/posterior pattern specification; dorsal/ventral pattern formation; embryonic digit morphogenesis; developmental growth; cartilage development involved in endochondral bone morphogenesis; positive regulation of chondrocyte differentiation | |
| HOXD13 | pattern specification process; regulation of branching involved in prostate gland morphogenesis; branch elongation of an epithelium; morphogenesis of an epithelial fold; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; embryonic hindgut morphogenesis; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; regulation of cell proliferation; male genitalia development; gland morphogenesis; anterior/posterior pattern specification; multicellular organismal development; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; skeletal system development | |
| HOXD3 | thyroid gland development; positive regulation of gene expression; anterior/posterior pattern specification; multicellular organismal development; Notch signaling pathway; cell-matrix adhesion; transcription, DNA-dependent; positive regulation of neuron differentiation; embryonic skeletal system morphogenesis; cartilage development | |
| HOXD4 | regulation of transcription, DNA-dependent; multicellular organismal development; anterior/posterior pattern specification; embryonic skeletal system morphogenesis; stem cell differentiation | |
| HOXD9 | peripheral nervous system neuron development; embryonic skeletal system morphogenesis; skeletal muscle tissue development; adult locomotory behavior; anterior/posterior pattern specification; positive regulation of transcription from RNA polymerase II promoter; multicellular organismal development; hindlimb morphogenesis; embryonic forelimb morphogenesis; mammary gland development; proximal/distal pattern formation | |
| HP1BP3 | nucleosome assembly | |
| HPD | tyrosine catabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; aromatic amino acid family metabolic process; L-phenylalanine catabolic process | |
| HPGDS | locomotory behavior; signal transduction; prostaglandin biosynthetic process; prostaglandin metabolic process; fatty acid biosynthetic process | |
| HPN | positive regulation of hepatocyte proliferation; positive regulation of thyroid hormone generation; pilomotor reflex; response to thyroid hormone stimulus; cochlea morphogenesis; potassium ion transmembrane transport; negative regulation of epithelial cell proliferation; detection of mechanical stimulus involved in sensory perception of sound; proteolysis; regulation of cell shape; positive regulation of gene expression; negative regulation of epithelial to mesenchymal transition; positive regulation of plasminogen activation; positive regulation of cell growth; basement membrane disassembly; negative regulation of apoptotic process; positive regulation by host of viral transcription | |
| HPS1 | eye pigmentation; retina development in camera-type eye; response to stimulus; pigmentation; secretion of lysosomal enzymes; positive regulation of natural killer cell activation; melanocyte differentiation; visual perception; blood coagulation; lysosome organization; organelle organization | |
| HPS3 | organelle organization; pigmentation | |
| HPS4 | organelle organization; hemostasis; blood coagulation; lysosome organization; positive regulation of eye pigmentation; protein stabilization; protein targeting; melanocyte differentiation | |
| HPS5 | pigmentation; blood coagulation; organelle organization | |
| HPS6 | organelle organization; pigmentation; melanocyte differentiation; blood coagulation | |
| HPSE | vascular wound healing; carbohydrate metabolic process; proteoglycan metabolic process; cell adhesion; cell-matrix adhesion; positive regulation vascular endothelial growth factor production; positive regulation of blood coagulation; positive regulation of osteoblast proliferation; regulation of hair follicle development; positive regulation of hair follicle development; positive regulation of protein kinase B signaling cascade | |
| HPSE2 | carbohydrate metabolic process | |
| HPX | regulation of protein metabolic process; positive regulation of interferon-gamma-mediated signaling pathway; interspecies interaction between organisms; heme metabolic process; hemoglobin metabolic process; heme transport; cellular iron ion homeostasis; transport; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of immunoglobulin production; positive regulation of tyrosine phosphorylation of Stat1 protein | |
| HR | regulation of transcription, DNA-dependent; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; protein heterooligomerization | |
| HRAS | positive regulation of transcription from RNA polymerase II promoter; leukocyte migration; positive regulation of DNA replication; negative regulation of neuron apoptosis; social behavior; positive regulation of Rac protein signal transduction; regulation of synaptic transmission, GABAergic; mitotic cell cycle G1/S transition checkpoint; actin cytoskeleton organization; positive regulation of JNK cascade; nerve growth factor receptor signaling pathway; regulation of long-term neuronal synaptic plasticity; positive regulation of epithelial cell proliferation; striated muscle cell differentiation; positive regulation of ERK1 and ERK2 cascade; cellular senescence; positive regulation of MAPK cascade; cell surface receptor signaling pathway; organ morphogenesis; chemotaxis; apoptotic process; endocytosis; positive regulation of protein phosphorylation; activation of MAPKK activity; cell cycle arrest; signal transduction; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction | |
| HRASLS | - | |
| HRASLS5 | - | |
| HRC | muscle contraction | |
| HRH1 | inflammatory response; G-protein coupled receptor signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; synaptic transmission; response to gravity; negative regulation of steroid biosynthetic process; positive regulation of nitric oxide biosynthetic process; positive regulation of vasoconstriction | |
| HRH2 | G-protein signaling, coupled to cyclic nucleotide second messenger; immune response | |
| HRH3 | G-protein signaling, coupled to cyclic nucleotide second messenger; neurotransmitter secretion | |
| HRH4 | inflammatory response | |
| HRSP12 | regulation of translational termination | |
| HS2ST1 | ureteric bud formation; heparin metabolic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | |
| HS3ST2 | circadian rhythm | |
| HS6ST3 | - | |
| HSD17B11 | steroid biosynthetic process; androgen catabolic process | |
| HSD17B12 | small molecule metabolic process; steroid biosynthetic process; cellular lipid metabolic process; positive regulation of cell-substrate adhesion; triglyceride biosynthetic process; extracellular matrix organization; long-chain fatty-acyl-CoA biosynthetic process | |
| HSD17B13 | - | |
| HSD17B14 | steroid catabolic process | |
| HSD17B4 | bile acid metabolic process; small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; bile acid biosynthetic process; fatty acid metabolic process; sterol transport | |
| HSD3B7 | bile acid metabolic process; regulation of cell growth; steroid biosynthetic process; bile acid biosynthetic process; small molecule metabolic process; oxidation-reduction process | |
| HSF1 | embryonic placenta development; embryonic process involved in female pregnancy; positive regulation of multicellular organism growth; negative regulation of tumor necrosis factor production; response to lipopolysaccharide; response to heat; negative regulation of cell proliferation; spermatogenesis; regulation of transcription, DNA-dependent; protein phosphorylation | |
| HSF2 | spermatogenesis; response to stress; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| HSF4 | negative regulation of transcription from RNA polymerase II promoter; protein homotrimerization; cell development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; camera-type eye development; histone H3-K9 demethylation; positive regulation of cell proliferation; response to stress; regulation of transcription, DNA-dependent | |
| HSF5 | - | |
| HSP90AB1 | positive regulation of nitric oxide biosynthetic process; placenta development; regulation of interferon-gamma-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway; innate immune response; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; axon guidance; response to unfolded protein; response to stress; protein folding | |
| HSP90B1 | regulation of phosphoprotein phosphatase activity; actin rod assembly; endoplasmic reticulum unfolded protein response; ER-associated protein catabolic process; protein transport; activation of signaling protein activity involved in unfolded protein response; response to stress; sequestering of calcium ion; anti-apoptosis; response to hypoxia; protein folding; cellular response to ATP | |
| HSPA12A | - | |
| HSPA12B | response to stress | |
| HSPA14 | 'de novo' cotranslational protein folding | |
| HSPA2 | response to unfolded protein; male meiosis; male meiosis I; spermatid development; positive regulation of cyclin-dependent protein kinase activity involved in G2/M; synaptonemal complex disassembly; response to stress; positive regulation of protein phosphorylation | |
| HSPA4L | protein folding; response to stress; response to unfolded protein | |
| HSPA5 | regulation of protein folding in endoplasmic reticulum; activation of signaling protein activity involved in unfolded protein response; proteolysis involved in cellular protein catabolic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; cellular response to glucose starvation; platelet degranulation; ATP catabolic process; anti-apoptosis; ER overload response; blood coagulation; cerebellum structural organization; cerebellar Purkinje cell layer development; platelet activation; ER-associated protein catabolic process; negative regulation of transforming growth factor beta receptor signaling pathway; endoplasmic reticulum unfolded protein response; positive regulation of protein ubiquitination | |
| HSPA9 | protein folding; protein export from nucleus; anti-apoptosis | |
| HSPG2 | angiogenesis; cartilage development involved in endochondral bone morphogenesis; cardiac muscle tissue development; embryonic skeletal system morphogenesis; small molecule metabolic process; lipoprotein metabolic process; extracellular matrix organization; protein localization; brain development; lipid metabolic process; chondrocyte differentiation; endochondral ossification | |
| HSPH1 | positive regulation of NK T cell activation; chaperone mediated protein folding requiring cofactor; positive regulation of MHC class I biosynthetic process; response to unfolded protein; response to stress | |
| HTR1A | behavior; positive regulation of cell proliferation; regulation of feeding behavior; serotonin receptor signaling pathway; inhibition of adenylate cyclase activity by serotonin receptor signaling pathway; G-protein coupled receptor signaling pathway | |
| HTR1B | synaptic transmission; G-protein coupled receptor internalization; G-protein coupled receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; serotonin receptor signaling pathway; response to toxin; regulation of dopamine secretion; negative regulation of cAMP biosynthetic process; negative regulation of synaptic transmission, GABAergic; cellular response to temperature stimulus; negative regulation of synaptic transmission, glutamatergic; response to mineralocorticoid stimulus; bone remodeling; response to ethanol; drinking behavior; response to drug; response to cocaine | |
| HTR1E | serotonin receptor signaling pathway; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway | |
| HTR1F | synaptic transmission; serotonin receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger | |
| HTR2C | ERK1 and ERK2 cascade; release of sequestered calcium ion into cytosol; response to drug; feeding behavior; synaptic transmission; serotonin receptor signaling pathway; phosphatidylinositol biosynthetic process; cGMP biosynthetic process | |
| HTR3A | ion transport; transmembrane transport; ion transmembrane transport; digestion; synaptic transmission; serotonin receptor signaling pathway; transport | |
| HTR3E | ion transmembrane transport; transmembrane transport | |
| HTR4 | activation of adenylate cyclase activity by G-protein signaling pathway; serotonin receptor signaling pathway; gamma-aminobutyric acid signaling pathway; positive regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway | |
| HTR5A | G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway; response to estradiol stimulus; hippocampus development; cAMP-mediated signaling; brain development; serotonin receptor signaling pathway | |
| HTRA1 | regulation of cell growth; proteolysis; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of BMP signaling pathway | |
| HTRA2 | positive regulation of intrinsic apoptotic signaling pathway; regulation of multicellular organism growth; execution phase of apoptosis; cellular response to growth factor stimulus; neuron development; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic process; proteolysis; forebrain development; positive regulation of cell death; induction of apoptosis by intracellular signals; adult walking behavior; cell cycle arrest; mitochondrion organization; response to stress; cleavage of cytoskeletal proteins involved in apoptosis | |
| HTRA4 | proteolysis; regulation of cell growth | |
| HTT | cell death; establishment of mitotic spindle orientation; retrograde vesicle-mediated transport, Golgi to ER; apoptotic process; Golgi organization; regulation of protein phosphatase type 2A activity; vesicle transport along microtubule; organ development; negative regulation of extrinsic apoptotic signaling pathway | |
| HUNK | signal transduction; multicellular organismal development | |
| HUWE1 | protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; cell differentiation; histone ubiquitination; protein monoubiquitination; base-excision repair; protein modification process | |
| HVCN1 | ion transport; proton transport; response to zinc ion; response to pH; transmembrane transport | |
| HYAL2 | entry of virus into host cell; positive regulation of protein import into nucleus; cartilage development; response to antibiotic; positive regulation of transcription from RNA polymerase II promoter; negative regulation of MAP kinase activity; positive regulation of apoptotic process; positive regulation of urine volume; negative regulation of protein kinase B signaling cascade; negative regulation of protein tyrosine kinase activity; renal water absorption; cellular response to interleukin-1; cellular response to tumor necrosis factor; negative regulation of cell growth; cellular response to transforming growth factor beta stimulus; cellular response to UV-B; response to virus; glycosaminoglycan catabolic process; carbohydrate metabolic process; translocation of virus into host cell; transformation of host cell by virus; hyaluronan catabolic process | |
| HYDIN | - | |
| HYKK | - | |
| HYOU1 | response to hypoxia; endoplasmic reticulum unfolded protein response; activation of signaling protein activity involved in unfolded protein response; response to stress | |
| IARS | gene expression; isoleucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| IARS2 | gene expression; tRNA aminoacylation for protein translation; isoleucyl-tRNA aminoacylation | |
| IBSP | biomineral tissue development; cellular response to growth factor stimulus; extracellular matrix organization; cell adhesion; ossification | |
| IBTK | negative regulation of protein phosphorylation; release of sequestered calcium ion into cytosol; negative regulation of protein tyrosine kinase activity | |
| ICA1 | neurotransmitter transport; regulation of protein homodimerization activity | |
| ICAM1 | negative regulation of calcium ion transport; cell adhesion mediated by integrin; cellular response to hypoxia; cellular response to tumor necrosis factor; cellular response to interleukin-1; cellular response to glucose stimulus; cellular response to alkaloid; cellular response to lipopolysaccharide; interferon-gamma-mediated signaling pathway; positive regulation of NF-kappaB transcription factor activity; adhesion to symbiont; interspecies interaction between organisms; positive regulation of nitric oxide biosynthetic process; response to ethanol; positive regulation of vasoconstriction; response to copper ion; virion attachment, binding of host cell surface receptor; regulation of immune response; leukocyte migration; regulation of cell shape; response to amphetamine; regulation of leukocyte mediated cytotoxicity; response to amino acid stimulus; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; T cell antigen processing and presentation; positive | |
| ICAM2 | cell-cell adhesion; regulation of immune response | |
| ICAM5 | cell-cell adhesion | |
| ICK | multicellular organismal development; intracellular protein kinase cascade; protein phosphorylation; signal transduction | |
| ICOS | immune response; T cell costimulation | |
| IDE | negative regulation of proteolysis; proteolysis involved in cellular protein catabolic process; protein heterooligomerization; protein homotetramerization; beta-amyloid metabolic process; interspecies interaction between organisms; hormone catabolic process; sex differentiation; signal transduction; proteolysis; bradykinin catabolic process | |
| IDH1 | isocitrate metabolic process; small molecule metabolic process; cellular lipid metabolic process; response to oxidative stress; glutathione metabolic process; NADPH regeneration; 2-oxoglutarate metabolic process; tricarboxylic acid cycle; glyoxylate cycle | |
| IDS | - | |
| IDUA | cell morphogenesis; carbohydrate metabolic process; disaccharide metabolic process; lysosome organization; limb morphogenesis; chemical homeostasis; skeletal system morphogenesis | |
| IER2 | - | |
| IER5 | - | |
| IFFO1 | - | |
| IFI16 | cell proliferation; regulation of transcription, DNA-dependent; response to virus; hemopoiesis; myeloid cell differentiation; monocyte differentiation; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; negative regulation of transcription, DNA-dependent | |
| IFI27 | induction of apoptosis by extracellular signals; type I interferon-mediated signaling pathway; cytokine-mediated signaling pathway; activation of pro-apoptotic gene products; activation of cysteine-type endopeptidase activity involved in apoptotic process | |
| IFI44 | response to virus | |
| IFI44L | immune response; response to virus | |
| IFIH1 | innate immune response; interspecies interaction between organisms; regulation of apoptotic process; positive regulation of interferon-alpha production; negative regulation of type I interferon production; detection of virus; positive regulation of interferon-beta production | |
| IFIT1B | - | |
| IFIT5 | - | |
| IFITM1 | regulation of immune response; innate immune response; cytokine-mediated signaling pathway; response to virus; cell surface receptor signaling pathway; negative regulation of cell proliferation; response to biotic stimulus; type I interferon-mediated signaling pathway | |
| IFNA5 | regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; innate immune response; cytokine-mediated signaling pathway; response to virus; blood coagulation | |
| IFNAR2 | cytokine-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; response to interferon-alpha; regulation of transcription from RNA polymerase II promoter; cell surface receptor signaling pathway; JAK-STAT cascade; cell proliferation; response to virus | |
| IFNB1 | innate immune response; positive regulation of innate immune response; regulation of MHC class I biosynthetic process; negative regulation of T cell differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of virion penetration into host cell; defense response to virus; type I interferon-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway; cellular response to exogenous dsRNA; negative regulation of T-helper 2 cell cytokine production; response to virus; defense response to bacterium; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; adaptive immune response; negative regulation of viral genome replication; humoral immune response; cell surface receptor signaling pathway; negative regulation of cell proliferation; cytokine-mediated signaling pathway; natural killer cell activation; blood coagulation; negative regulation of viral transcription; B cell proliferation | |
| IFNE | defense response; response to virus | |
| IFNGR1 | signal transduction; response to virus; cytokine-mediated signaling pathway; interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway | |
| IFNGR2 | cytokine-mediated signaling pathway; response to virus; cell surface receptor signaling pathway; interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway | |
| IFNK | defense response; regulation of transcription, DNA-dependent; positive regulation of innate immune response; natural killer cell activation; cytokine-mediated signaling pathway; response to virus; negative regulation of cell proliferation | |
| IFNLR1 | - | |
| IFNW1 | defense response; response to virus; cell cycle arrest | |
| IFRD1 | multicellular organismal development; myoblast cell fate determination; adult somatic muscle development; muscle cell differentiation | |
| IFT122 | cilium morphogenesis; limb development; camera-type eye morphogenesis; embryonic heart tube development; cell projection organization; embryonic body morphogenesis; multicellular organismal development; neural tube closure | |
| IFT140 | - | |
| IFT172 | cilium assembly; smoothened signaling pathway; neural tube formation; protein processing; dorsal/ventral pattern formation; determination of left/right symmetry; multicellular organismal development | |
| IFT43 | intraflagellar retrograde transport; cilium morphogenesis; cell projection organization | |
| IFT46 | protein stabilization; intraflagellar transport; flagellum assembly | |
| IFT57 | regulation of transcription, DNA-dependent; apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of apoptotic process | |
| IFT74 | - | |
| IGDCC3 | neuromuscular process controlling balance | |
| IGDCC4 | - | |
| IGF1R | positive regulation of anti-apoptosis; immune response; anti-apoptosis; male sex determination; positive regulation of cell migration; mammary gland development; exocrine pancreas development; neuron projection development; positive regulation of cytokinesis; response to vitamin E; negative regulation of apoptotic process; positive regulation of MAPK cascade; positive regulation of DNA replication; establishment of cell polarity; regulation of JNK cascade; protein autophosphorylation; insulin-like growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; protein tetramerization; protein heterooligomerization; inactivation of MAPKK activity; positive regulation of protein kinase B signaling cascade; negative regulation of protein kinase B signaling cascade; prostate gland epithelium morphogenesis; positive regulation of steroid hormone biosynthetic process; axonogenesis; brain development; positive regulation of cell proliferation; signal transduction; phosphatidylinositol 3-kinase cas | |
| IGF2BP2 | anatomical structure morphogenesis; negative regulation of translation; regulation of cytokine biosynthetic process | |
| IGF2R | receptor-mediated endocytosis; signal transduction; insulin-like growth factor receptor signaling pathway | |
| IGFALS | cell adhesion; signal transduction | |
| IGFBP2 | regulation of cell growth; response to lithium ion; response to glucocorticoid stimulus; regulation of insulin-like growth factor receptor signaling pathway; positive regulation of activated T cell proliferation; response to stress; signal transduction; female pregnancy; aging; response to nutrient; response to mechanical stimulus; response to drug; response to estradiol stimulus; response to retinoic acid; cellular response to hormone stimulus | |
| IGFBPL1 | regulation of cell growth | |
| IGFL3 | - | |
| IGFLR1 | - | |
| IGFN1 | - | |
| IGHMBP2 | DNA duplex unwinding; cell death; protein homooligomerization; DNA replication; translation; regulation of transcription, DNA-dependent; DNA recombination; DNA repair; negative regulation of transcription from RNA polymerase II promoter | |
| IGSF1 | regulation of transcription, DNA-dependent; signal transduction | |
| IGSF10 | cell differentiation; multicellular organismal development; ossification; tissue regeneration | |
| IGSF11 | regulation of growth; cell adhesion | |
| IGSF21 | - | |
| IGSF22 | - | |
| IGSF3 | - | |
| IGSF5 | - | |
| IGSF8 | cellular component movement; single fertilization; nervous system development; skeletal muscle tissue development; cell proliferation | |
| IKBIP | response to X-ray; induction of apoptosis | |
| IKBKAP | protein phosphorylation; protein complex assembly; regulation of transcription from RNA polymerase II promoter; immune response; signal transduction; I-kappaB phosphorylation; transcription elongation from RNA polymerase II promoter | |
| IKBKE | positive regulation of I-kappaB kinase/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; negative regulation of type I interferon production; toll-like receptor 4 signaling pathway; immune response; toll-like receptor 3 signaling pathway; NIK/NF-kappaB cascade; response to DNA damage stimulus; innate immune response; protein phosphorylation; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; DNA damage response, signal transduction resulting in induction of apoptosis | |
| IKZF3 | regulation of B cell differentiation; regulation of transcription from RNA polymerase II promoter; mesoderm development; regulation of lymphocyte differentiation; regulation of B cell proliferation; B cell activation; regulation of apoptotic process | |
| IL10RA | signal transduction | |
| IL10RB | immune response; inflammatory response; signal transduction | |
| IL12A | positive regulation of cell adhesion; defense response to Gram-positive bacterium; positive regulation of T cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; immune response; cell cycle arrest; response to virus; response to UV-B; cell migration; response to lipopolysaccharide; negative regulation of interleukin-17 production; positive regulation of interferon-gamma production; positive regulation of smooth muscle cell apoptosis; positive regulation of NK T cell activation; positive regulation of lymphocyte proliferation; negative regulation of smooth muscle cell proliferation; positive regulation of natural killer cell mediated cytotoxicity; defense response to protozoan; positive regulation of tyrosine phosphorylation of Stat4 protein; positive regulation of T cell proliferation; positive regulation of natural killer cell activation | |
| IL12RB2 | positive regulation of interferon-gamma production; cell surface receptor signaling pathway; positive regulation of cell proliferation; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; response to lipopolysaccharide; response to cytokine stimulus | |
| IL13 | response to ethanol; positive regulation of release of sequestered calcium ion into cytosol; response to lipopolysaccharide; response to nicotine; positive regulation of macrophage activation; positive regulation of B cell proliferation; regulation of proton transport; cell-cell signaling; signal transduction; immune response; inflammatory response; cellular component movement; negative regulation of transforming growth factor beta production; positive regulation of immunoglobulin production; cellular response to cytokine stimulus; cellular response to mechanical stimulus; positive regulation of protein secretion; positive regulation of smooth muscle cell proliferation; positive regulation of ion transport | |
| IL13RA1 | cell surface receptor signaling pathway | |
| IL13RA2 | signal transduction; cytokine-mediated signaling pathway | |
| IL15RA | cytokine-mediated signaling pathway; positive regulation of natural killer cell differentiation; cell proliferation; signal transduction | |
| IL16 | regulation of transcription, DNA-dependent; chemotaxis; immune response; leukocyte chemotaxis; interspecies interaction between organisms; induction of positive chemotaxis | |
| IL17A | protein glycosylation; apoptotic process; inflammatory response; immune response; cell-cell signaling; cell death; positive regulation of interleukin-23 production; positive regulation of transcription from RNA polymerase II promoter; cellular response to interleukin-1; cellular response to glucocorticoid stimulus; fibroblast activation; positive regulation of osteoclast differentiation | |
| IL17C | neutrophil differentiation; cell-cell signaling; inflammatory response; cell surface receptor signaling pathway | |
| IL17D | inflammatory response | |
| IL17F | inflammatory response; cartilage development; proteoglycan metabolic process; positive regulation of transcription from RNA polymerase II promoter; regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; regulation of interleukin-8 biosynthetic process; regulation of interleukin-6 biosynthetic process; regulation of interleukin-2 biosynthetic process; lymphotoxin A biosynthetic process; cytokine biosynthetic process; regulation of transforming growth factor beta receptor signaling pathway; negative regulation of angiogenesis | |
| IL17RA | cell surface receptor signaling pathway; positive regulation of interleukin-23 production; fibroblast activation | |
| IL17RE | - | |
| IL18R1 | innate immune response; immune response; signal transduction | |
| IL18RAP | inflammatory response; immune response; signal transduction; cell surface receptor signaling pathway; innate immune response | |
| IL1A | positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-2 biosynthetic process; positive regulation of angiogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of JNK cascade; response to copper ion; positive regulation of cytokine secretion; positive regulation of cell division; regulation of sensory perception of pain; positive regulation of ERK1 and ERK2 cascade; positive regulation of mitosis; cellular response to heat; fever generation; response to hypoxia; apoptotic process; anti-apoptosis; inflammatory response; immune response; cell proliferation; negative regulation of cell proliferation; response to ozone; response to organic nitrogen; response to gamma radiation; wound healing; positive regulation vascular endothelial growth factor production; positive regulation of steroid biosynthetic process; response to organic cyclic compound; cytokine-mediated signaling pathway; keratinization; response to lipopolysaccharide; | |
| IL1R2 | immune response | |
| IL1RAP | protein complex assembly; inflammatory response; immune response; signal transduction; innate immune response | |
| IL1RAPL1 | signal transduction; regulation of neuron projection development; negative regulation of calcium ion transport via voltage-gated calcium channel activity; negative regulation of exocytosis; innate immune response | |
| IL1RAPL2 | signal transduction; central nervous system development; innate immune response | |
| IL1RL1 | signal transduction; immune response; negative regulation of T-helper 1 type immune response; cytokine-mediated signaling pathway; negative regulation of interferon-gamma production; positive regulation of interleukin-5 production; positive regulation of macrophage activation; negative regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; positive regulation of inflammatory response; positive regulation of chemokine secretion | |
| IL1RL2 | cellular defense response; signal transduction; innate immune response | |
| IL20RA | - | |
| IL21 | positive regulation of inflammatory response; positive regulation of natural killer cell cytokine production; immune response; signal transduction; positive regulation of interleukin-10 production; positive regulation of interleukin-17 production; positive regulation of natural killer cell differentiation; positive regulation of tissue remodeling; positive regulation of T cell proliferation; positive regulation of interferon-gamma biosynthetic process; positive regulation of natural killer cell mediated cytotoxicity; cell maturation | |
| IL21R | natural killer cell activation | |
| IL22 | cell-cell signaling; acute-phase response; inflammatory response | |
| IL22RA1 | - | |
| IL23A | positive regulation of interleukin-10 production; positive regulation of NK T cell proliferation; positive regulation of neutrophil chemotaxis; positive regulation of memory T cell differentiation; positive regulation of interleukin-12 production; positive regulation of T-helper 17 type immune response; positive regulation of T-helper 17 cell lineage commitment; positive regulation of interleukin-17 production; positive regulation of NK T cell activation; positive regulation of interferon-gamma production; positive regulation of T cell mediated cytotoxicity; positive regulation of defense response to virus by host; positive regulation of granulocyte macrophage colony-stimulating factor production; negative regulation of interleukin-10 production; positive regulation of activation of JAK2 kinase activity; response to virus; positive regulation of T-helper 1 type immune response; positive regulation of osteoclast differentiation; positive regulation of natural killer cell proliferation; positive regulation of t | |
| IL23R | positive regulation of interleukin-12 production; positive regulation of tyrosine phosphorylation of Stat4 protein; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of memory T cell differentiation; positive regulation of osteoclast differentiation; defense response to Gram-negative bacterium; positive regulation of NK T cell activation; positive regulation of T-helper 17 type immune response; positive regulation of T-helper 17 cell lineage commitment; positive regulation of interferon-gamma production; positive regulation of natural killer cell proliferation; positive regulation of T-helper 1 type immune response; positive regulation of defense response to virus by host; positive regulation of T cell mediated cytotoxicity; positive regulation of interleukin-17 production; response to interferon-gamma; positive regulation of T cell proliferation; positive regulation of activated T cell proliferation; regulation of tyrosine phosphorylation of Stat1 protein; positive regulat | |
| IL24 | apoptotic process | |
| IL25 | inflammatory response to antigenic stimulus; response to fungus; response to nematode; eosinophil differentiation | |
| IL27RA | cell surface receptor signaling pathway; positive regulation of T-helper 1 type immune response; negative regulation of type 2 immune response; positive regulation of interferon-gamma production; immune response; regulation of isotype switching to IgG isotypes; defense response to Gram-positive bacterium | |
| IL2RA | inflammatory response to antigenic stimulus; apoptotic process; activation-induced cell death of T cells; immune response; cell surface receptor signaling pathway; cell proliferation; cytokine-mediated signaling pathway; positive regulation of activated T cell proliferation; negative regulation of T cell proliferation; positive regulation of apoptotic process; positive regulation of T cell differentiation; regulation of T cell homeostatic proliferation; negative regulation of defense response to virus; negative regulation of inflammatory response; negative regulation of immune response | |
| IL34 | positive regulation of cell proliferation; positive regulation of protein phosphorylation; inflammatory response; innate immune response | |
| IL36B | immune response | |
| IL37 | immune response | |
| IL4 | positive regulation of chemokine biosynthetic process; connective tissue growth factor biosynthetic process; regulation of isotype switching; type 2 immune response; positive regulation of MHC class II biosynthetic process; negative regulation of nitric oxide biosynthetic process; negative regulation of apoptotic process; negative regulation of macrophage activation; positive regulation of tyrosine phosphorylation of Stat5 protein; response to drug; regulation of phosphorylation; positive regulation of activated T cell proliferation; positive regulation of T cell proliferation; dendritic cell differentiation; response to ethanol; positive regulation of T cell differentiation; negative regulation of osteoclast differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of isotype switching to IgE isotypes; positive regulation of isotype switching to IgG isotyp | |
| IL4I1 | - | |
| IL4R | negative regulation of T-helper 1 cell differentiation; response to estrogen stimulus; positive regulation of macrophage activation; regulation of cell proliferation; interleukin-4-mediated signaling pathway; ovulation; signal transduction; immune response; production of molecular mediator involved in inflammatory response; positive regulation of T-helper 2 cell differentiation; positive regulation of chemokine secretion | |
| IL5RA | signal transduction; cell proliferation; interleukin-5-mediated signaling pathway | |
| IL6 | positive regulation of acute inflammatory response; regulation of cell shape; monocyte chemotaxis; positive regulation of leukocyte chemotaxis; negative regulation of protein kinase activity; acute-phase response; inflammatory response; humoral immune response; aging; positive regulation of cell proliferation; negative regulation of cell proliferation; response to mechanical stimulus; neutrophil mediated immunity; hepatic immune response; neutrophil apoptosis; cell growth; cytokine-mediated signaling pathway; platelet activation; response to organic cyclic compound; negative regulation of lipid storage; regulation of vascular endothelial growth factor production; response to bacterium; response to heat; response to cold; positive regulation of osteoblast differentiation; response to antibiotic; positive regulation of JAK-STAT cascade; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of anti-apoptosis; regulation of a | |
| IL6R | acute-phase response; positive regulation of activation of Janus kinase activity; response to gamma radiation; positive regulation of cell proliferation; response to ethanol; cell growth; cytokine-mediated signaling pathway; endocrine pancreas development; response to lipopolysaccharide; negative regulation of interleukin-8 production; positive regulation of chemokine production; positive regulation of interleukin-6 production; negative regulation of collagen biosynthetic process; response to cytokine stimulus; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of apoptotic process; positive regulation of MAPK cascade; response to peptide hormone stimulus; monocyte chemotaxis; response to glucocorticoid stimulus; positive regulation of NF-kappaB transcription factor activity; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of smooth muscle cell proliferation; positi | |
| IL6ST | positive regulation of smooth muscle cell migration; positive regulation of T cell proliferation; response to cytokine stimulus; cytokine-mediated signaling pathway; positive regulation of acute inflammatory response; positive regulation of adaptive immune response; triglyceride mobilization; JAK-STAT cascade; response to nutrient; positive regulation of cell proliferation; positive regulation vascular endothelial growth factor production; positive regulation of cardiac muscle hypertrophy; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of osteoblast differentiation; positive regulation of anti-apoptosis; leukemia inhibitory factor signaling pathway; reduction of cytosolic calcium ion concentration; interleukin-6-mediated signaling pathway; negative regulation of interleukin-6-mediated signaling pathway; interleukin-27-mediated signaling pathway; ciliary neurotrophic factor-mediated signaling pathway | |
| ILDR1 | - | |
| ILDR2 | homeostasis of number of cells within a tissue; pancreas development; cell differentiation; insulin secretion; response to glucose stimulus | |
| ILF3 | M phase; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent | |
| ILK | positive regulation of canonical Wnt receptor signaling pathway; positive regulation of BMP signaling pathway; positive regulation of protein kinase B signaling cascade; protein heterooligomerization; positive regulation of dendrite morphogenesis; neuron projection morphogenesis; negative regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; positive regulation of axon extension; positive regulation of osteoblast differentiation; positive regulation of myoblast differentiation; establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of neuron apoptosis; positive regulation of MAPK cascade; positive regulation of MAP kinase activity; fibril organization; positive regulation of phosphorylation; substrate adhesion-dependent cell spreading; cell junction assembly; regulation of actin cytoskeleton organization; myelin assembly; positive regulation of cell-matrix adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; cel | |
| ILKAP | protein dephosphorylation; negative regulation of cell cycle; regulation of S phase of mitotic cell cycle | |
| ILVBL | - | |
| IMMP2L | spermatogenesis; ovulation; ovarian follicle development; proteolysis; protein processing involved in protein targeting to mitochondrion | |
| IMP4 | rRNA processing | |
| IMPDH1 | purine nucleotide biosynthetic process; nucleobase-containing small molecule metabolic process; lymphocyte proliferation; small molecule metabolic process; purine ribonucleoside monophosphate biosynthetic process; purine base metabolic process; GMP biosynthetic process | |
| IMPDH2 | nucleobase-containing small molecule metabolic process; purine nucleotide biosynthetic process; GMP biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; small molecule metabolic process; lymphocyte proliferation; purine base metabolic process | |
| IMPG1 | visual perception | |
| IMPG2 | visual perception | |
| INADL | intracellular signal transduction; cell junction assembly; cell-cell junction organization; tight junction assembly | |
| INF2 | cellular component organization; actin cytoskeleton organization | |
| ING1 | protein import into nucleus; cell cycle; negative regulation of cell proliferation; regulation of cell death; negative regulation of cell growth; positive regulation of transcription, DNA-dependent | |
| ING2 | regulation of transcription, DNA-dependent; male meiosis I; signal transduction; spermatogenesis; spermatid development; chromatin modification; sperm motility; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of growth; negative regulation of apoptotic process; positive regulation of transcription, DNA-dependent; male germ-line stem cell division; seminiferous tubule development; regulation of cellular senescence; regulation of response to DNA damage stimulus | |
| ING4 | histone H4-K8 acetylation; positive regulation of apoptotic process; DNA replication; protein acetylation; apoptotic process; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; cell cycle; cell cycle arrest; negative regulation of cell proliferation; chromatin modification; negative regulation of growth; negative regulation of transcription, DNA-dependent; histone H4-K16 acetylation; histone H4-K12 acetylation; histone H4-K5 acetylation; histone H3 acetylation | |
| ING5 | DNA replication; protein acetylation; negative regulation of cell proliferation; chromatin modification; histone H3 acetylation; positive regulation of transcription, DNA-dependent; negative regulation of growth | |
| INHA | cell cycle arrest; positive regulation of follicle-stimulating hormone secretion; induction of apoptosis; ovarian follicle development; skeletal system development; negative regulation of follicle-stimulating hormone secretion; cell surface receptor signaling pathway; negative regulation of cell cycle; negative regulation of macrophage differentiation; negative regulation of B cell differentiation; negative regulation of interferon-gamma biosynthetic process; hemoglobin biosynthetic process; negative regulation of phosphorylation; regulation of cell proliferation; cell differentiation; response to external stimulus; male gonad development; nervous system development; regulation of cell cycle; cell-cell signaling; signal transduction; erythrocyte differentiation | |
| INHBA | positive regulation of transcription from RNA polymerase II promoter; regulation of follicle-stimulating hormone secretion; positive regulation of follicle-stimulating hormone secretion; negative regulation of follicle-stimulating hormone secretion; mesodermal cell differentiation; palate development; positive regulation of ovulation; eyelid development in camera-type eye; cellular response to follicle-stimulating hormone stimulus; cellular response to cholesterol; regulation of transcription from RNA polymerase II promoter; growth; positive regulation of transcription, DNA-dependent; regulation of activin receptor signaling pathway; negative regulation of cell growth; erythrocyte differentiation; cell differentiation; male gonad development; negative regulation of cell proliferation; nervous system development; cell-cell signaling; cell surface receptor signaling pathway; cell cycle arrest; defense response; induction of apoptosis; hemopoietic progenitor cell differentiation; hair follicle development; ovari | |
| INHBE | growth | |
| INO80 | ATP catabolic process; positive regulation of transcription from RNA polymerase II promoter; cellular response to UV; DNA duplex unwinding; positive regulation of cell growth; positive regulation of DNA replication involved in S phase; cell cycle; chromatin remodeling; DNA recombination; double-strand break repair; cell division; double-strand break repair via homologous recombination; mitotic sister chromatid segregation; spindle assembly; UV-damage excision repair; cellular response to ionizing radiation; regulation of G1/S transition of mitotic cell cycle | |
| INO80B | DNA repair; DNA recombination; regulation of transcription, DNA-dependent | |
| INPP4B | phosphatidylinositol-3-phosphate biosynthetic process; signal transduction | |
| INPP5A | phosphatidylinositol phosphorylation; cell communication | |
| INPP5B | signal transduction; small GTPase mediated signal transduction; phosphatidylinositol phosphorylation; phosphatidylinositol dephosphorylation; regulation of small GTPase mediated signal transduction | |
| INPP5E | phosphatidylinositol phosphorylation; dephosphorylation; positive regulation of neuron projection development; lipid metabolic process | |
| INPP5F | - | |
| INPPL1 | negative regulation of platelet-derived growth factor receptor signaling pathway; cellular lipid metabolic process; negative regulation of neuron projection development; response to insulin stimulus; inositol trisphosphate metabolic process; response to drug; negative regulation of MAP kinase activity; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of insulin receptor signaling pathway; phosphatidylinositol phosphorylation; post-embryonic development; negative regulation of cell proliferation; negative regulation of DNA replication; brain development; cell adhesion; actin filament organization; negative regulation of gene expression; endocytosis; glucose metabolic process | |
| INSC | nervous system development; establishment of mitotic spindle orientation; multicellular organismal development; cell differentiation; lung epithelial cell differentiation | |
| INSM2 | regulation of transcription, DNA-dependent | |
| INSR | positive regulation of MAPK cascade; signal transduction by phosphorylation; transformation of host cell by virus; male sex determination; positive regulation of cell migration; exocrine pancreas development; response to nutrient levels; activation of protein kinase activity; activation of protein kinase B activity; response to estradiol stimulus; negative regulation of transporter activity; response to insulin stimulus; cellular response to insulin stimulus; response to vitamin D; response to testosterone stimulus; response to tumor necrosis factor; positive regulation of phosphorylation; glucose homeostasis; insulin receptor signaling pathway; positive regulation of nitric oxide biosynthetic process; activation of MAPK activity; negative regulation of protein phosphorylation; positive regulation of protein phosphorylation; heart morphogenesis; carbohydrate metabolic process; regulation of transcription, DNA-dependent; G-protein coupled receptor signaling pathway; positive regulation of cell proliferation; p | |
| INSRR | transmembrane receptor protein tyrosine kinase signaling pathway; male sex determination; actin cytoskeleton reorganization; protein autophosphorylation; cellular response to alkalinity | |
| INTS10 | snRNA processing | |
| INTS5 | snRNA processing | |
| INTS6 | snRNA processing | |
| INTS7 | cellular response to ionizing radiation; DNA damage checkpoint; snRNA processing | |
| INTU | cilium assembly; limb development; nervous system development; regulation of smoothened signaling pathway | |
| INVS | negative regulation of canonical Wnt receptor signaling pathway; kidney development; post-embryonic development; Wnt receptor signaling pathway; pancreas development; embryonic heart tube left/right pattern formation | |
| IP6K1 | phosphatidylinositol phosphorylation | |
| IP6K2 | phosphatidylinositol phosphorylation; type I interferon-mediated signaling pathway; cytokine-mediated signaling pathway; positive regulation of apoptotic process; negative regulation of cell growth | |
| IP6K3 | protein phosphorylation; inositol phosphate biosynthetic process; phosphatidylinositol metabolic process | |
| IPCEF1 | response to oxidative stress; oxygen transport; positive regulation of GTP catabolic process | |
| IPO11 | intracellular protein transport | |
| IPO13 | protein import into nucleus; intracellular protein transport | |
| IPO4 | intracellular protein transport; protein transport | |
| IPO5 | NLS-bearing substrate import into nucleus; interspecies interaction between organisms; ribosomal protein import into nucleus; intracellular protein transport | |
| IPO7 | interspecies interaction between organisms; signal transduction; intracellular protein transport; transport; protein import into nucleus | |
| IPO8 | intracellular protein transport; signal transduction | |
| IPO9 | intracellular protein transport; protein transport; protein import into nucleus | |
| IPP | - | |
| IPPK | inositol phosphorylation | |
| IQCB1 | maintenance of organ identity; photoreceptor cell maintenance; cilium assembly | |
| IQCC | - | |
| IQCD | - | |
| IQCE | - | |
| IQCG | - | |
| IQCH | - | |
| IQGAP1 | positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; glomerular visceral epithelial cell development; energy reserve metabolic process; signal transduction; small molecule metabolic process; regulation of insulin secretion | |
| IQGAP2 | regulation of small GTPase mediated signal transduction; signal transduction | |
| IQGAP3 | signal transduction; positive regulation of mammary gland epithelial cell proliferation; ERK1 and ERK2 cascade; negative regulation of gene expression; positive regulation of gene expression; regulation of small GTPase mediated signal transduction; cellular response to organic substance; Ras protein signal transduction; regulation of cell size; positive regulation of protein phosphorylation; activation of MAPK activity; G1/S transition of mitotic cell cycle | |
| IQSEC1 | regulation of ARF protein signal transduction | |
| IQSEC3 | regulation of ARF protein signal transduction | |
| IQUB | - | |
| IRAK1 | TRIF-dependent toll-like receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; NIK/NF-kappaB cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JUN kinase activity; innate immune response; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; protein autophosphorylation; nerve growth factor receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; protein oligomerization; stress-activated MAPK cascade; nucleotide-binding oligomerization domain containing signaling pathway; interleukin-1-mediated signaling pathway; response to interleukin-1; negative regulation of cholesterol efflux; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; activation of MAPK activity; regulation of cytokine-mediated signaling pathway; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathwa | |
| IRAK2 | MyD88-independent toll-like receptor signaling pathway; toll-like receptor 1 signaling pathway; negative regulation of NF-kappaB transcription factor activity; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; innate immune response; positive regulation of NF-kappaB transcription factor activity; stress-activated MAPK cascade; nucleotide-binding oligomerization domain containing signaling pathway; interleukin-1-mediated signaling pathway; response to interleukin-1; Toll signaling pathway; activation of MAPK activity; regulation of cytokine-mediated signaling pathway; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; protein phosphorylation; inflammatory response; signal transduction; I-kappaB kinase/NF-kappaB cascade; JNK cascade; lipopolysaccharide-mediated sign | |
| IRAK3 | response to virus; response to exogenous dsRNA; negative regulation of MAP kinase activity; response to interleukin-1; positive regulation of macrophage tolerance induction; negative regulation of innate immune response; regulation of protein complex disassembly; protein autophosphorylation; positive regulation of NF-kappaB transcription factor activity; negative regulation of protein complex disassembly; negative regulation of protein catabolic process; negative regulation of toll-like receptor signaling pathway; negative regulation of interleukin-6 production; signal transduction; negative regulation of macrophage cytokine production; protein phosphorylation; MyD88-dependent toll-like receptor signaling pathway; negative regulation of cytokine-mediated signaling pathway; cytokine-mediated signaling pathway; negative regulation of NF-kappaB transcription factor activity; response to peptidoglycan; response to lipopolysaccharide; negative regulation of interleukin-12 production; interleukin-1-mediated signali | |
| IRAK4 | toll-like receptor 1 signaling pathway; cytokine production; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; signal transduction; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; innate immune response; toll-like receptor 4 signaling pathway; toll-like receptor 2 signaling pathway; cytokine-mediated signaling pathway; Toll signaling pathway; JNK cascade; protein phosphorylation | |
| IREB2 | cellular iron ion homeostasis; metabolic process; post-embryonic development; regulation of gene expression; osteoclast differentiation; erythrocyte homeostasis; intestinal absorption; regulation of translation; protoporphyrinogen IX biosynthetic process; iron ion transport | |
| IRF1 | positive regulation of cell death; blood coagulation; female pregnancy; I-kappaB kinase/NF-kappaB cascade; transcription from RNA polymerase II promoter; response to heat; cellular response to peptide hormone stimulus; cellular response to dsRNA; cellular response to tumor necrosis factor; cellular response to interleukin-1; cellular response to retinoic acid; response to growth hormone stimulus; cellular response to mechanical stimulus; positive regulation of interleukin-12 biosynthetic process; CD8-positive, alpha-beta T cell differentiation; negative regulation of tyrosine phosphorylation of Stat1 protein; cytokine-mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway | |
| IRF2BP1 | regulation of transcription, DNA-dependent | |
| IRF2BP2 | regulation of transcription, DNA-dependent | |
| IRF2BPL | - | |
| IRF3 | interspecies interaction between organisms; innate immune response; toll-like receptor 4 signaling pathway; type I interferon biosynthetic process; negative regulation of interferon-beta biosynthetic process; negative regulation of defense response to virus by host; positive regulation of cytokine secretion; interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway; cellular response to dsRNA; positive regulation of I-kappaB kinase/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; response to lipopolysaccharide; negative regulation of type I interferon production; lipopolysaccharide-mediated signaling pathway; cytokine-mediated signaling pathway; response to bacterium; response to virus; response to exogenous dsRNA; Toll signaling pathway; negative regulation of transcription from RNA polymerase II promoter; MyD88-independent toll-like receptor signaling pathway; transcription from RNA polymerase II promoter | |
| IRF6 | mammary gland epithelial cell differentiation; type I interferon-mediated signaling pathway; interferon-gamma-mediated signaling pathway; cell development; positive regulation of transcription, DNA-dependent; skin development; keratinocyte differentiation; cytokine-mediated signaling pathway; negative regulation of cell proliferation; cell cycle arrest; keratinocyte proliferation | |
| IRF9 | type I interferon-mediated signaling pathway; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; cell surface receptor signaling pathway; response to virus; cytokine-mediated signaling pathway; type I interferon biosynthetic process; interferon-gamma-mediated signaling pathway | |
| IRS1 | response to peptide hormone stimulus; positive regulation of phosphatidylinositol 3-kinase activity; glucose homeostasis; positive regulation of phosphorylation; protein localization to nucleus; cellular response to insulin stimulus; response to insulin stimulus; positive regulation of fatty acid beta-oxidation; mammary gland development; positive regulation of cell migration; lipid catabolic process; phosphatidylinositol 3-kinase cascade; positive regulation of glucose metabolic process; regulation of gene expression; insulin receptor signaling pathway; positive regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; positive regulation of mesenchymal cell proliferation; protein kinase B signaling cascade; negative regulation of somatostatin secretion; positive regulation of glucagon secretion; JAK-STAT cascade involved in growth hormone signaling pathway; protein heterooligomerization; phosphatidylinositol-mediated signaling; nerve growth fact | |
| IRS2 | negative regulation of plasma membrane long-chain fatty acid transport; response to glucose stimulus; insulin receptor signaling pathway; positive regulation of cell proliferation; brain development; signal transduction; glucose metabolic process; negative regulation of B cell apoptosis; positive regulation of mesenchymal cell proliferation; negative regulation of kinase activity; positive regulation of cell migration; JAK-STAT cascade involved in growth hormone signaling pathway; lipid homeostasis; phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; cellular response to insulin stimulus; positive regulation of insulin secretion; positive regulation of fatty acid beta-oxidation; positive regulation of B cell proliferation; mammary gland development; regulation of lipid metabolic process; positive regulation of glucose metabolic process | |
| IRS4 | signal transduction | |
| IRX6 | - | |
| ISG15 | response to virus; cytokine-mediated signaling pathway; modification-dependent protein catabolic process; ISG15-protein conjugation; negative regulation of type I interferon production; interspecies interaction between organisms; innate immune response; cell-cell signaling; type I interferon-mediated signaling pathway | |
| ISG20L2 | ribosome biogenesis | |
| ISL1 | pituitary gland development; retinal ganglion cell axon guidance; axon regeneration; pancreas development; trigeminal nerve development; visceral motor neuron differentiation; spinal cord motor neuron differentiation; spinal cord motor neuron cell fate specification; positive regulation of insulin secretion; negative regulation of transcription from RNA polymerase II promoter; neural crest cell migration; secondary heart field specification; outflow tract septum morphogenesis; outflow tract morphogenesis; endocardial cushion morphogenesis; cardiac right ventricle morphogenesis; regulation of secondary heart field cardioblast proliferation; multicellular organismal development; positive regulation of cell proliferation; negative regulation of canonical Wnt receptor signaling pathway; pharyngeal system development; ventricular cardiac muscle tissue morphogenesis; peripheral nervous system neuron axonogenesis; sensory system development; cardiac muscle cell myoblast differentiation; innervation; atrial septum mo | |
| ISL2 | peripheral nervous system neuron development; multicellular organismal development; neuron development | |
| ISLR2 | positive regulation of axon extension; nervous system development; multicellular organismal development | |
| ISM2 | - | |
| ISX | - | |
| ISYNA1 | phospholipid biosynthetic process; inositol biosynthetic process | |
| ITCH | protein modification process; inflammatory response; response to virus; protein ubiquitination; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production; protein K29-linked ubiquitination; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of apoptotic process; interspecies interaction between organisms; innate immune response; negative regulation of JNK cascade; entry of virus into host cell; negative regulation of defense response to virus; protein K63-linked ubiquitination; protein K48-linked ubiquitination; regulation of protein deubiquitination; nucleotide-binding oligomerization domain containing signaling pathway; ubiquitin-dependent protein catabolic process; regulation of cell growth | |
| ITGA1 | muscle contraction; neuron projection morphogenesis; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; axon guidance; neutrophil chemotaxis; vasodilation; positive regulation of neuron apoptosis; cellular extravasation; cell chemotaxis; activation of MAPK activity | |
| ITGA10 | cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway | |
| ITGA2 | interspecies interaction between organisms; organ morphogenesis; blood coagulation; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; axon guidance | |
| ITGA2B | cell-matrix adhesion; platelet activation; blood coagulation; axon guidance; integrin-mediated signaling pathway; cell adhesion; platelet degranulation | |
| ITGA4 | B cell differentiation; regulation of immune response; blood coagulation; heart development; integrin-mediated signaling pathway; leukocyte cell-cell adhesion; heterophilic cell-cell adhesion; cell adhesion; blood vessel remodeling; chorio-allantoic fusion; face development; leukocyte migration | |
| ITGA5 | leukocyte cell-cell adhesion; heterophilic cell-cell adhesion; cell adhesion; cell-substrate junction assembly; integrin-mediated signaling pathway; angiogenesis; leukocyte migration; positive regulation of peptidyl-tyrosine phosphorylation; interspecies interaction between organisms; wound healing, spreading of epidermal cells; cell-cell adhesion mediated by integrin; positive regulation of vascular endothelial growth factor receptor signaling pathway; memory; blood coagulation; axon guidance | |
| ITGA6 | positive regulation of transcription from RNA polymerase II promoter; positive regulation of apoptotic process; positive regulation of phosphorylation; cell junction assembly; hemidesmosome assembly; blood coagulation; integrin-mediated signaling pathway; cell adhesion; cell-substrate junction assembly; negative regulation of apoptotic process; leukocyte migration | |
| ITGA7 | cell-matrix adhesion; cell adhesion; regulation of cell shape; muscle organ development; integrin-mediated signaling pathway | |
| ITGA8 | positive regulation of transforming growth factor beta receptor signaling pathway; metanephros development; inner ear morphogenesis; extracellular matrix organization; cell differentiation; cell projection organization; cell-cell adhesion; memory; nervous system development; multicellular organismal development; integrin-mediated signaling pathway; cell-matrix adhesion | |
| ITGA9 | wound healing; axon guidance; integrin-mediated signaling pathway; cell adhesion | |
| ITGAD | integrin-mediated signaling pathway; cell-cell adhesion; activated T cell proliferation; cell-matrix adhesion; cell adhesion; immune response | |
| ITGAE | cell adhesion; integrin-mediated signaling pathway | |
| ITGAL | positive regulation of T cell proliferation; leukocyte migration; positive regulation of calcium-mediated signaling; regulation of immune response; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; cellular component movement; inflammatory response; cell adhesion; heterophilic cell-cell adhesion; leukocyte cell-cell adhesion; signal transduction; integrin-mediated signaling pathway; blood coagulation; positive regulation of cell-cell adhesion; activated T cell proliferation | |
| ITGAV | cell adhesion; regulation of apoptotic cell clearance; ERK1 and ERK2 cascade; entry of symbiont into host cell by promotion of host phagocytosis; leukocyte migration; regulation of phagocytosis; negative regulation of lipoprotein metabolic process; entry of virus into host cell; positive regulation of cell adhesion; blood vessel development; integrin-mediated signaling pathway; axon guidance; blood coagulation; positive regulation of cell proliferation; negative regulation of macrophage derived foam cell differentiation; cell-matrix adhesion; negative regulation of low-density lipoprotein particle receptor biosynthetic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; angiogenesis; negative regulation of lipid storage; positive regulation of cell migration; negative regulation of lipid transport; positive regulation of osteoblast proliferation; entry of bacterium into host cell; anti | |
| ITGAX | leukocyte migration; defense response to virus; organ morphogenesis; blood coagulation; integrin-mediated signaling pathway; cell adhesion | |
| ITGB2 | cell-matrix adhesion; apoptotic process; inflammatory response; cell adhesion; leukocyte cell-cell adhesion; leukocyte migration; regulation of immune response; regulation of peptidyl-tyrosine phosphorylation; neutrophil chemotaxis; regulation of cell shape; blood coagulation; multicellular organismal development; cell-cell signaling; integrin-mediated signaling pathway | |
| ITGB5 | antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; muscle contraction; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; multicellular organismal development | |
| ITGB6 | cell adhesion; interspecies interaction between organisms; multicellular organismal development; integrin-mediated signaling pathway; cell-matrix adhesion; inflammatory response | |
| ITGB7 | cell adhesion; regulation of immune response; multicellular organismal development; integrin-mediated signaling pathway; cell-matrix adhesion | |
| ITGB8 | ganglioside metabolic process; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; multicellular organismal development; placenta blood vessel development | |
| ITGBL1 | cell-matrix adhesion; cell adhesion; integrin-mediated signaling pathway | |
| ITIH1 | hyaluronan metabolic process; leukocyte activation | |
| ITIH2 | negative regulation of endopeptidase activity; hyaluronan metabolic process | |
| ITIH4 | hyaluronan metabolic process; negative regulation of endopeptidase activity; acute-phase response | |
| ITIH5 | hyaluronan metabolic process | |
| ITIH6 | hyaluronan metabolic process | |
| ITM2B | induction of apoptosis; nervous system development; apoptotic process | |
| ITPA | nucleotide metabolic process; metabolic process | |
| ITPKB | positive thymic T cell selection; positive regulation of Ras protein signal transduction; signal transduction; MAPK cascade; positive regulation of alpha-beta T cell differentiation; cell surface receptor signaling pathway; T cell differentiation | |
| ITPKC | - | |
| ITPR2 | platelet activation; nerve growth factor receptor signaling pathway; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; ion transport; transport; energy reserve metabolic process; response to hypoxia; small molecule metabolic process; inositol phosphate-mediated signaling; regulation of insulin secretion; transmembrane transport; calcium ion transmembrane transport; cellular response to cAMP; blood coagulation; fibroblast growth factor receptor signaling pathway | |
| ITPR3 | sensory perception of sweet taste; nerve growth factor receptor signaling pathway; sensory perception of bitter taste; regulation of insulin secretion; inositol phosphate-mediated signaling; signal transduction; sensory perception of umami taste; protein homooligomerization; protein heterooligomerization; response to calcium ion; transmembrane transport; calcium ion transport into cytosol; platelet activation; epidermal growth factor receptor signaling pathway; ion transport; energy reserve metabolic process; G-protein coupled receptor signaling pathway; activation of phospholipase C activity; elevation of cytosolic calcium ion concentration; blood coagulation; fibroblast growth factor receptor signaling pathway; small molecule metabolic process | |
| ITPRIPL1 | - | |
| ITPRIPL2 | - | |
| ITSN1 | positive regulation of catalytic activity; regulation of Rho protein signal transduction; apoptotic process; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals; positive regulation of protein kinase B signaling cascade; regulation of small GTPase mediated signal transduction; synaptic vesicle endocytosis; nerve growth factor receptor signaling pathway; negative regulation of neuron apoptosis | |
| ITSN2 | endocytosis; regulation of Rho protein signal transduction | |
| IVNS1ABP | RNA splicing; response to virus; transcription from RNA polymerase III promoter; interspecies interaction between organisms | |
| IZUMO1 | fusion of sperm to egg plasma membrane; cell adhesion | |
| IZUMO2 | - | |
| JADE1 | response to stress; negative regulation of cell growth; histone H3 acetylation; histone H4-K5 acetylation; apoptotic process; regulation of transcription, DNA-dependent; histone H4-K8 acetylation; histone H4-K12 acetylation; histone H4-K16 acetylation | |
| JADE3 | histone H4-K12 acetylation; histone H4-K16 acetylation; histone H4-K5 acetylation; histone H3 acetylation; histone H4-K8 acetylation | |
| JAG2 | cell cycle; thymic T cell selection; regulation of apoptotic process; odontogenesis of dentin-containing tooth; regulation of cell proliferation; regulation of cell migration; T cell differentiation; regulation of cell adhesion; cell differentiation; morphogenesis of embryonic epithelium; auditory receptor cell fate commitment; spermatogenesis; multicellular organismal development; Notch receptor processing; Notch signaling pathway; skeletal system development; in utero embryonic development; respiratory system process; cell communication | |
| JAK1 | response to antibiotic; intracellular signal transduction; type I interferon-mediated signaling pathway; cytokine-mediated signaling pathway; peptidyl-tyrosine phosphorylation; intracellular protein kinase cascade; enzyme linked receptor protein signaling pathway; interferon-gamma-mediated signaling pathway; protein phosphorylation; regulation of interferon-gamma-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway | |
| JAK2 | response to antibiotic; protein autophosphorylation; regulation of inflammatory response; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of nitric-oxide synthase biosynthetic process; interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; growth hormone receptor signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; tumor necrosis factor-mediated signaling pathway; positive regulation of growth hormone receptor signaling pathway; mammary gland epithelium development; response to interleukin-12; tyrosine phosphorylation of STAT protein; chromatin modification; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of cell-substrate adhesion; activation of caspase activity by protein phosphorylation; negative regulation of cell proliferation; blood coagulation; mesoderm development; STAT protein import into nucleus; negative regulation of DNA binding; JAK-STAT cascade; intracellu | |
| JAK3 | peptidyl-tyrosine phosphorylation; response to interleukin-9; response to interleukin-15; response to interleukin-4; response to interleukin-2; negative regulation of thymocyte apoptosis; regulation of T cell apoptosis; JAK-STAT cascade involved in growth hormone signaling pathway; B cell differentiation; negative regulation of FasL biosynthetic process; innate immune response; T cell homeostasis; regulation of apoptotic process; tyrosine phosphorylation of Stat5 protein; positive regulation of activated T cell proliferation; negative regulation of interleukin-12 production; negative regulation of interleukin-10 production; negative regulation of T cell activation; cytokine-mediated signaling pathway; STAT protein import into nucleus; tyrosine phosphorylation of STAT protein; intracellular protein kinase cascade; elevation of cytosolic calcium ion concentration; enzyme linked receptor protein signaling pathway; protein phosphorylation; negative regulation of dendritic cell cytokine production; positive regula | |
| JAKMIP1 | protein transport | |
| JAKMIP2 | - | |
| JAM3 | angiogenesis; blood coagulation; cell adhesion; leukocyte migration; regulation of neutrophil chemotaxis | |
| JARID2 | stem cell differentiation; negative regulation of transcription from RNA polymerase II promoter; liver development; multicellular organismal development; central nervous system development; positive regulation of histone H3-K9 methylation; negative regulation of cell proliferation; chromatin modification; negative regulation of histone methylation; negative regulation of transcription, DNA-dependent; thymus development; spleen development | |
| JCHAIN | immune response | |
| JMJD1C | chromatin modification; blood coagulation; regulation of transcription, DNA-dependent | |
| JMY | cell cycle arrest; DNA repair; positive regulation of sequence-specific DNA binding transcription factor activity; actin polymerization-dependent cell motility; Arp2/3 complex-mediated actin nucleation; positive regulation of apoptotic process; induction of apoptosis; 'de novo' actin filament nucleation; regulation of transcription from RNA polymerase II promoter | |
| JOSD2 | protein deubiquitination; proteolysis | |
| JPH1 | muscle organ development; regulation of ryanodine-sensitive calcium-release channel activity; calcium ion transport into cytosol | |
| JPH2 | positive regulation of ryanodine-sensitive calcium-release channel activity; calcium ion homeostasis; regulation of ryanodine-sensitive calcium-release channel activity; regulation of cardiac muscle tissue development; calcium ion transport into cytosol | |
| JPH3 | exploration behavior; locomotion; regulation of neuronal synaptic plasticity; memory; regulation of ryanodine-sensitive calcium-release channel activity; calcium ion transport into cytosol | |
| JPH4 | regulation of ryanodine-sensitive calcium-release channel activity; calcium ion transport into cytosol | |
| JRKL | regulation of transcription, DNA-dependent; central nervous system development | |
| JTB | mitosis; negative regulation of apoptotic process; positive regulation of protein kinase activity; cell division; regulation of cell proliferation; cell cycle cytokinesis; cell cycle | |
| JUNB | response to organic cyclic compound; osteoclast differentiation; cellular process; response to progesterone stimulus; cellular response to hormone stimulus; osteoblast proliferation; response to cytokine stimulus; response to drug; response to peptide hormone stimulus; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter during mitosis; decidualization; response to corticosterone stimulus; response to cAMP; regulation of cell cycle; embryonic process involved in female pregnancy; labyrinthine layer blood vessel development; cellular response to calcium ion; response to mechanical stimulus; response to light stimulus; regulation of transcription from RNA polymerase II promoter; trophectodermal cell differentiation; in utero embryonic development; osteoblast differentiation; vasculogenesis | |
| JUP | gastrulation; negative regulation of transcription from RNA polymerase II promoter; cell morphogenesis; desmosome assembly; negative regulation of heart induction by canonical Wnt receptor signaling pathway; atrioventricular valve morphogenesis; negative regulation of Wnt receptor signaling pathway involved in heart development; cytoskeletal anchoring at plasma membrane; positive regulation of protein import into nucleus; ectoderm development; nervous system development; morphogenesis of embryonic epithelium; cell-cell adhesion; cell migration; cell junction assembly; adherens junction organization; skin development; cell-cell junction organization; oocyte development; detection of mechanical stimulus; positive regulation of sequence-specific DNA binding transcription factor activity; endothelial cell-cell adhesion; cellular response to indole-3-methanol; positive regulation of canonical Wnt receptor signaling pathway | |
| KALRN | small GTPase mediated signal transduction; intracellular signal transduction; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction; regulation of Rho protein signal transduction; vesicle-mediated transport; induction of apoptosis by extracellular signals; nervous system development; signal transduction; apoptotic process; protein phosphorylation | |
| KANK1 | negative regulation of actin filament polymerization | |
| KANK2 | - | |
| KANK3 | - | |
| KANK4 | - | |
| KANSL1L | - | |
| KARS | gene expression; tRNA aminoacylation for protein translation; lysyl-tRNA aminoacylation; tRNA processing; interspecies interaction between organisms | |
| KAT2A | histone deubiquitination; somitogenesis; interspecies interaction between organisms; histone H3-K14 acetylation; histone H3 acetylation; regulation of apoptotic process; multicellular organism growth; midbrain development; metencephalon development; cell proliferation; in utero embryonic development; neural tube closure; chromatin remodeling; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nervous system development; telencephalon development | |
| KAT2B | negative regulation of cyclin-dependent protein kinase activity; negative regulation of phosphorylation; protein acetylation; cellular response to insulin stimulus; transcription initiation from RNA polymerase I promoter; histone H3 acetylation; interspecies interaction between organisms; peptidyl-lysine acetylation; N-terminal peptidyl-lysine acetylation; gene expression; negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase I promoter; chromatin remodeling; cell cycle; cell cycle arrest; Notch signaling pathway | |
| KAT5 | regulation of growth; positive regulation of transcription, DNA-dependent; interspecies interaction between organisms; histone acetylation; chromatin modification; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; double-strand break repair; negative regulation of transcription from RNA polymerase II promoter; androgen receptor signaling pathway; negative regulation of transcription, DNA-dependent; negative regulation of interleukin-2 production | |
| KAT6A | nucleosome assembly; chromatin modification; histone acetylation; myeloid cell differentiation; DNA packaging; histone H3 acetylation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent | |
| KAT6B | chromatin modification; histone acetylation; regulation of transcription, DNA-dependent; histone H3 acetylation; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nucleosome assembly | |
| KAT7 | histone H3 acetylation; histone H4-K16 acetylation; histone H4-K12 acetylation; chromatin modification; regulation of transcription, DNA-dependent; histone H4-K8 acetylation; DNA replication; histone H4-K5 acetylation | |
| KATNA1 | mitosis; protein localization; cell cycle; neuron migration; negative regulation of neuron projection development; cytoplasmic microtubule organization; microtubule severing; cell division; interphase of mitotic cell cycle | |
| KATNAL1 | - | |
| KATNAL2 | - | |
| KAZN | keratinization | |
| KBTBD2 | - | |
| KBTBD3 | - | |
| KBTBD4 | - | |
| KBTBD6 | - | |
| KCNA1 | ion transport; potassium ion transport; synaptic transmission; transmembrane transport; potassium ion transmembrane transport | |
| KCNA10 | transmembrane transport; synaptic transmission; ion transport; potassium ion transport | |
| KCNA2 | ion transport; potassium ion transmembrane transport; transmembrane transport; potassium ion transport; synaptic transmission | |
| KCNA3 | ion transport; potassium ion transport; synaptic transmission; regulation of ion transmembrane transport; transmembrane transport | |
| KCNA4 | ion transport; potassium ion transport; synaptic transmission; transmembrane transport | |
| KCNA5 | potassium ion transport; response to hypoxia; ion transport; synaptic transmission; regulation of membrane potential; negative regulation of potassium ion transport; protein oligomerization; reduction of cytosolic calcium ion concentration; potassium ion homeostasis; transmembrane transport | |
| KCNA7 | transmembrane transport; potassium ion transport; ion transport; synaptic transmission | |
| KCNAB1 | transmembrane transport; ion transport; potassium ion transport; synaptic transmission | |
| KCNAB2 | ion transport; potassium ion transport; synaptic transmission; transmembrane transport | |
| KCNAB3 | synaptic transmission; transmembrane transport; potassium ion transport; ion transport | |
| KCNB1 | energy reserve metabolic process; ion transport; potassium ion transport; synaptic transmission; small molecule metabolic process; regulation of insulin secretion; transmembrane transport | |
| KCNB2 | ion transport; potassium ion transport; transmembrane transport; synaptic transmission; regulation of smooth muscle contraction | |
| KCNC2 | transmembrane transport; regulation of insulin secretion; small molecule metabolic process; potassium ion transport; ion transport; energy reserve metabolic process; synaptic transmission | |
| KCNC4 | ion transport; potassium ion transport; synaptic transmission; regulation of neurotransmitter secretion; transmembrane transport; potassium ion transmembrane transport | |
| KCND1 | synaptic transmission; ion transport; potassium ion transport; transmembrane transport | |
| KCND2 | regulation of action potential; ion transport; potassium ion transport; synaptic transmission; protein heterooligomerization; transmembrane transport | |
| KCND3 | ion transport; potassium ion transport; synaptic transmission; transmembrane transport | |
| KCNE1 | sensory perception of sound; potassium ion export; blood circulation; regulation of heart contraction; membrane depolarization; muscle contraction; potassium ion transport; ion transport; epithelial cell maturation | |
| KCNE4 | ion transport; potassium ion transport | |
| KCNG2 | potassium ion transport; synaptic transmission; regulation of heart contraction; small molecule metabolic process; regulation of insulin secretion; transmembrane transport; ion transport; energy reserve metabolic process | |
| KCNG3 | synaptic transmission; ion transport; potassium ion transport; transmembrane transport | |
| KCNG4 | potassium ion transport; ion transport; transmembrane transport; synaptic transmission | |
| KCNH1 | myoblast fusion; transmembrane transport; potassium ion transport; ion transport; regulation of transcription, DNA-dependent | |
| KCNH2 | regulation of transcription, DNA-dependent; ion transport; potassium ion transport; muscle contraction; synaptic transmission; blood circulation; regulation of heart contraction; regulation of membrane potential; transmembrane transport; protein heterooligomerization | |
| KCNH3 | transmembrane transport; regulation of transcription, DNA-dependent; synaptic transmission; potassium ion transport; ion transport | |
| KCNH4 | regulation of transcription, DNA-dependent; ion transport; potassium ion transport; synaptic transmission; transmembrane transport | |
| KCNH5 | regulation of transcription, DNA-dependent; transmembrane transport; synaptic transmission; potassium ion transport; ion transport | |
| KCNH6 | regulation of transcription, DNA-dependent; ion transport; potassium ion transport; signal transduction; synaptic transmission; transmembrane transport; protein heterooligomerization | |
| KCNH7 | protein heterooligomerization; circadian rhythm; transmembrane transport; regulation of transcription, DNA-dependent; synaptic transmission; potassium ion transport; ion transport | |
| KCNH8 | regulation of transcription, DNA-dependent; ion transport; potassium ion transport; synaptic transmission; negative regulation of apoptotic process; transmembrane transport | |
| KCNIP3 | sensory perception of pain; signal transduction; behavior; apoptotic process; potassium ion transport; ion transport; regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; response to pain; regulation of transcription from RNA polymerase II promoter | |
| KCNIP4 | ion transport; potassium ion transport | |
| KCNJ1 | synaptic transmission; potassium ion transport; excretion; ion transport | |
| KCNJ10 | regulation of long-term neuronal synaptic plasticity; ion transport; potassium ion transport; inflammatory response; synaptic transmission; visual perception; adult walking behavior; response to blue light; potassium ion import; optic nerve development; central nervous system myelination; protein homotetramerization; response to glucocorticoid stimulus; response to mineralocorticoid stimulus; regulation of sensory perception of pain; glutamate uptake involved in synaptic transmission; potassium ion homeostasis; regulation of resting membrane potential; membrane hyperpolarization | |
| KCNJ11 | neurological system process; glucose metabolic process; potassium ion transport; synaptic transmission; potassium ion import; response to ATP; response to testosterone stimulus; regulation of membrane potential; response to drug; small molecule metabolic process; negative regulation of insulin secretion; regulation of insulin secretion; ion transport; energy reserve metabolic process | |
| KCNJ14 | ion transport; potassium ion transport; synaptic transmission | |
| KCNJ16 | potassium ion transport; synaptic transmission; ion transport | |
| KCNJ3 | response to electrical stimulus; synaptic transmission; potassium ion transport; ion transport | |
| KCNJ4 | potassium ion transport; ion transport; synaptic transmission | |
| KCNJ5 | ion transport; potassium ion transport; synaptic transmission | |
| KCNJ6 | response to electrical stimulus; thyroid hormone metabolic process; synaptic transmission; potassium ion transport; ion transport | |
| KCNJ8 | synaptic transmission; heart development; response to pH; potassium ion transport; ion transport; kidney development; potassium ion import; response to lipopolysaccharide; vasodilation; response to exogenous dsRNA; defense response to virus | |
| KCNK10 | signal transduction; synaptic transmission; potassium ion transport; ion transport; transport; potassium ion transmembrane transport | |
| KCNK13 | potassium ion transmembrane transport; synaptic transmission; ion transport; potassium ion transport | |
| KCNK2 | ion transport; potassium ion transport; G-protein coupled receptor signaling pathway; synaptic transmission; potassium ion transmembrane transport | |
| KCNK3 | brain development; cochlea development; potassium ion transmembrane transport; cellular response to hypoxia; cellular response to zinc ion; reduction of cytosolic calcium ion concentration; response to drug; synaptic transmission; potassium ion transport; ion transport | |
| KCNK4 | synaptic transmission; potassium ion transport; ion transport; potassium ion transmembrane transport | |
| KCNK6 | ion transport; potassium ion transport; synaptic transmission | |
| KCNK7 | potassium ion transmembrane transport; ion transport; potassium ion transport; synaptic transmission | |
| KCNMA1 | response to carbon monoxide; cellular potassium ion homeostasis; smooth muscle contraction involved in micturition; potassium ion transport; ion transport; response to hypoxia; potassium ion transmembrane transport; micturition; transmembrane transport; response to calcium ion; negative regulation of cell volume; positive regulation of apoptotic process; regulation of membrane potential; response to osmotic stress; synaptic transmission; blood coagulation | |
| KCNMB1 | ion transport; potassium ion transport; synaptic transmission; blood coagulation; response to calcium ion; potassium ion transmembrane transport | |
| KCNMB2 | synaptic transmission; regulation of action potential; ion transport; regulation of vasoconstriction; detection of calcium ion; blood coagulation; regulation of action potential in neuron; potassium ion transmembrane transport; potassium ion transport | |
| KCNMB3 | ion transport; detection of calcium ion; regulation of action potential; potassium ion transmembrane transport; regulation of action potential in neuron; potassium ion transport; blood coagulation; synaptic transmission | |
| KCNMB4 | blood coagulation; synaptic transmission; regulation of action potential; detection of calcium ion; ion transport; potassium ion transport; potassium ion transmembrane transport; regulation of neurotransmitter secretion; regulation of vasoconstriction; regulation of action potential in neuron | |
| KCNN2 | ion transport; potassium ion transmembrane transport; synaptic transmission; potassium ion transport | |
| KCNN3 | ion transport; potassium ion transport; synaptic transmission; potassium ion transmembrane transport | |
| KCNQ1 | regulation of gene expression by genetic imprinting; potassium ion export; regulation of membrane repolarization; transmembrane transport; negative regulation of insulin secretion; response to chemical stimulus; gene silencing; regulation of heart contraction; blood circulation; sensory perception of sound; synaptic transmission; muscle contraction; potassium ion transport; ion transport | |
| KCNQ2 | ion transport; potassium ion transport; synaptic transmission; axon guidance; transmembrane transport; potassium ion transmembrane transport; nervous system development | |
| KCNQ3 | potassium ion transmembrane transport; transmembrane transport; axon guidance; synaptic transmission; potassium ion transport; ion transport | |
| KCNQ5 | protein complex assembly; ion transport; potassium ion transport; transmembrane transport; synaptic transmission | |
| KCNRG | potassium ion transport | |
| KCNS1 | ion transport; potassium ion transport; synaptic transmission; transmembrane transport | |
| KCNS2 | ion transport; potassium ion transport; synaptic transmission; transmembrane transport | |
| KCNS3 | transmembrane transport; energy reserve metabolic process; ion transport; potassium ion transport; synaptic transmission; small molecule metabolic process; regulation of insulin secretion | |
| KCNT1 | ion transport; potassium ion transport; potassium ion transmembrane transport | |
| KCNT2 | potassium ion transport; ion transport; potassium ion transmembrane transport | |
| KCNV1 | ion transport; transmembrane transport; synaptic transmission; potassium ion transport | |
| KCTD10 | proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; potassium ion transport | |
| KCTD13 | proteasomal ubiquitin-dependent protein catabolic process; DNA replication; stress fiber assembly; negative regulation of Rho protein signal transduction; protein ubiquitination; cell migration; potassium ion transport | |
| KCTD16 | potassium ion transport | |
| KCTD18 | potassium ion transport | |
| KCTD19 | potassium ion transport | |
| KCTD21 | potassium ion transport | |
| KCTD3 | potassium ion transport | |
| KCTD4 | potassium ion transport | |
| KCTD8 | potassium ion transport | |
| KDELC1 | - | |
| KDELC2 | - | |
| KDM1A | negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of DNA damage response, signal transduction by p53 class mediator; protein demethylation; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; multicellular organismal development; positive regulation of sequence-specific DNA binding transcription factor activity; blood coagulation; muscle cell development; oxidation-reduction process; chromatin modification; negative regulation of DNA binding; negative regulation of protein binding; histone H3-K9 demethylation; histone H3-K4 demethylation; negative regulation of apoptotic process | |
| KDM1B | regulation of gene expression by genetic imprinting; DNA methylation involved in gamete generation; regulation of DNA methylation; regulation of transcription, DNA-dependent; multicellular organismal development; histone H3-K4 demethylation; chromatin modification | |
| KDM2B | negative regulation of neural precursor cell proliferation; embryonic camera-type eye morphogenesis; negative regulation of neuron apoptosis; forebrain development; histone H2A monoubiquitination; hindbrain development; midbrain development; histone demethylation; midbrain-hindbrain boundary morphogenesis; fourth ventricle development; lateral ventricle development; third ventricle development; initiation of neural tube closure; chromatin modification; regulation of transcription, DNA-dependent; spermatogenesis; negative regulation of transcription from RNA polymerase II promoter | |
| KDM3A | spermatogenesis; hormone-mediated signaling pathway; chromatin modification; cell differentiation; androgen receptor signaling pathway; histone H3-K9 demethylation; positive regulation of transcription, DNA-dependent; formaldehyde biosynthetic process | |
| KDM3B | chromatin modification; regulation of transcription, DNA-dependent | |
| KDM4A | chromatin modification; histone H3-K36 demethylation; negative regulation of transcription, DNA-dependent; interspecies interaction between organisms; histone demethylation | |
| KDM4B | regulation of transcription, DNA-dependent; chromatin modification | |
| KDM4C | regulation of transcription from RNA polymerase II promoter; histone H3-K9 demethylation; chromatin modification; positive regulation of cell proliferation | |
| KDM5A | regulation of transcription, DNA-dependent; chromatin modification; multicellular organismal development; positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| KDM5B | negative regulation of transcription, DNA-dependent; histone H3-K4 demethylation, trimethyl-H3-K4-specific; histone H3-K4 demethylation; chromatin modification; regulation of transcription, DNA-dependent | |
| KDM5C | regulation of transcription, DNA-dependent; chromatin modification; histone H3-K4 demethylation | |
| KDM6A | chromatin modification; histone H3-K4 methylation | |
| KDM6B | negative regulation of transcription from RNA polymerase II promoter; inflammatory response; chromatin modification; histone demethylation | |
| KDM7A | nervous system development; chromatin modification; midbrain development; histone H3-K9 demethylation; histone H4-K20 demethylation; positive regulation of transcription, DNA-dependent; histone H3-K36 demethylation; histone H3-K27 demethylation | |
| KDR | signal transduction by phosphorylation; positive regulation of angiogenesis; peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of endothelial cell migration; regulation of cell shape; positive regulation of cell proliferation; multicellular organismal development; transmembrane receptor protein tyrosine kinase signaling pathway; endothelium development; positive regulation of mesenchymal cell proliferation; lymph vessel development; positive regulation of endothelial cell proliferation; vasculogenesis; ovarian follicle development; angiogenesis; embryonic hemopoiesis; endothelial cell differentiation; cell fate commitment; interspecies interaction between organisms; positive regulation of MAPK cascade; protein autophosphorylation; vascular endothelial growth factor receptor signaling pathway; lung alveolus development; cell maturation; branching morphogenesis of a tube; positive regulation of positive chemotaxis; positive regulation of focal a | |
| KEAP1 | regulation of transcription, DNA-dependent; negative regulation of gene expression; cytoplasmic sequestering of transcription factor; in utero embryonic development; regulation of epidermal cell differentiation | |
| KEL | proteolysis; vasoconstriction | |
| KERA | visual perception; response to stimulus | |
| KHDRBS1 | cell cycle arrest; G2/M transition of mitotic cell cycle; mRNA processing; cell cycle; signal transduction; cell surface receptor signaling pathway; cell proliferation; negative regulation of transcription, DNA-dependent; regulation of RNA export from nucleus | |
| KHK | carbohydrate metabolic process; response to sucrose stimulus; response to glucose stimulus; response to fructose stimulus; fructose catabolic process; small molecule metabolic process; response to insulin stimulus; response to zinc ion | |
| KHNYN | - | |
| KIAA0100 | - | |
| KIAA0141 | apoptotic process; regulation of cysteine-type endopeptidase activity involved in apoptotic process | |
| KIAA0196 | cell death | |
| KIAA0319 | negative regulation of dendrite development; nervous system development; multicellular organismal development; neuron migration | |
| KIAA0319L | - | |
| KIAA0355 | - | |
| KIAA0391 | tRNA processing | |
| KIAA0430 | negative regulation of phosphatase activity | |
| KIAA0513 | - | |
| KIAA0556 | - | |
| KIAA0753 | - | |
| KIAA0825 | - | |
| KIAA0895 | - | |
| KIAA0907 | - | |
| KIAA0922 | - | |
| KIAA0930 | - | |
| KIAA1024 | - | |
| KIAA1033 | endosome transport | |
| KIAA1109 | regulation of epithelial cell differentiation; regulation of cell growth | |
| KIAA1211 | - | |
| KIAA1211L | - | |
| KIAA1217 | embryonic skeletal system development; multicellular organismal development | |
| KIAA1324 | positive regulation of autophagic vacuole assembly; positive regulation of vacuole organization; regulation of apoptotic process; macroautophagy | |
| KIAA1324L | - | |
| KIAA1429 | mRNA processing; RNA splicing | |
| KIAA1462 | cell adhesion | |
| KIAA1468 | - | |
| KIAA1522 | - | |
| KIAA1524 | - | |
| KIAA1551 | - | |
| KIAA1614 | - | |
| KIAA1683 | - | |
| KIAA1715 | embryonic digit morphogenesis; embryonic forelimb morphogenesis; blood coagulation; multicellular organismal development; limb development | |
| KIAA1755 | - | |
| KIAA1804 | - | |
| KIAA1841 | - | |
| KIAA1919 | transmembrane transport; ion transport; carbohydrate transport; sodium ion transport | |
| KIAA1958 | - | |
| KIAA2022 | DNA replication proofreading; DNA replication, removal of RNA primer; regulation of mitotic cell cycle; S phase of mitotic cell cycle; nucleotide-excision repair, DNA gap filling; base-excision repair, gap-filling | |
| KIDINS220 | nerve growth factor receptor signaling pathway; activation of MAPKK activity | |
| KIF11 | mitotic spindle organization; spindle assembly involved in mitosis; cell division; blood coagulation; mitotic centrosome separation; mitosis; spindle organization; cell cycle; microtubule-based movement | |
| KIF14 | microtubule-based movement | |
| KIF15 | cell proliferation; microtubule-based movement; mitosis; blood coagulation | |
| KIF16B | receptor catabolic process; microtubule-based movement; cell communication; epidermal growth factor receptor signaling pathway; endoderm development; fibroblast growth factor receptor signaling pathway; Golgi to endosome transport; transport; early endosome to late endosome transport; regulation of receptor recycling; formation of primary germ layer | |
| KIF17 | microtubule-based movement; metabolic process; protein transport; vesicle-mediated transport; protein complex localization | |
| KIF1B | ATP catabolic process; apoptotic process; microtubule-based movement; neuron-neuron synaptic transmission; anterograde axon cargo transport; neuromuscular synaptic transmission; cytoskeleton-dependent intracellular transport | |
| KIF1C | retrograde vesicle-mediated transport, Golgi to ER; microtubule-based movement | |
| KIF20A | mitotic cell cycle; vesicle-mediated transport; M phase of mitotic cell cycle; cytokinesis; microtubule bundle formation; protein transport; microtubule-based movement | |
| KIF20B | regulation of mitosis; cell division; M phase of mitotic cell cycle; ATP catabolic process; microtubule-based movement; cell cycle; cell cycle arrest | |
| KIF21A | microtubule-based movement | |
| KIF21B | microtubule-based movement | |
| KIF22 | blood coagulation; mitosis; microtubule-based movement; DNA repair | |
| KIF23 | mitosis; microtubule-based movement; blood coagulation; cell cycle cytokinesis; M phase of mitotic cell cycle; mitotic spindle elongation; mitotic cell cycle; spindle midzone assembly involved in mitosis; positive regulation of cell cycle cytokinesis; cytokinesis | |
| KIF25 | microtubule-based movement; organelle organization; mitotic sister chromatid segregation | |
| KIF2B | microtubule-based movement; microtubule depolymerization; regulation of chromosome segregation; M phase of mitotic cell cycle; mitotic prometaphase; blood coagulation; cell division; mitotic cell cycle | |
| KIF3A | organelle organization; blood coagulation; cilium assembly; plus-end-directed vesicle transport along microtubule; microtubule-based movement; cell projection organization | |
| KIF3B | microtubule-based movement; spindle assembly involved in mitosis; plus-end-directed vesicle transport along microtubule; anterograde axon cargo transport; determination of left/right symmetry; mitotic spindle organization; mitotic centrosome separation; blood coagulation | |
| KIF3C | microtubule-based movement; blood coagulation | |
| KIF4A | organelle organization; axon guidance; blood coagulation; microtubule-based movement; anterograde axon cargo transport | |
| KIF5A | microtubule-based movement; synaptic transmission; blood coagulation; cell death | |
| KIF5B | vesicle transport along microtubule; microtubule-based movement; cytoplasm organization; stress granule disassembly | |
| KIF6 | microtubule-based movement | |
| KIF7 | positive regulation of smoothened signaling pathway; negative regulation of smoothened signaling pathway; microtubule-based movement | |
| KIFAP3 | blood coagulation; protein complex assembly; microtubule-based movement; microtubule-based process; plus-end-directed vesicle transport along microtubule; signal transduction; protein localization; positive regulation of calcium-dependent cell-cell adhesion; negative regulation of cell proliferation | |
| KIFC2 | microtubule-based movement | |
| KIRREL | excretion | |
| KISS1R | neuropeptide signaling pathway; positive regulation of stress fiber assembly; positive regulation of synaptic transmission; arachidonic acid secretion; positive regulation of hormone secretion; negative regulation of cell migration; activation of MAPKK activity; calcium-mediated signaling; negative regulation of cell proliferation; behavior; G-protein coupled receptor signaling pathway | |
| KIT | intracellular protein kinase cascade; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phospholipase C activity; positive regulation of gene expression; response to radiation; male gonad development; positive regulation of cell proliferation; spermatid development; positive regulation of tyrosine phosphorylation of Stat5 protein; spermatogenesis; glycosphingolipid metabolic process; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; activation of MAPK activity; myeloid progenitor cell differentiation; lymphoid progenitor cell differentiation; positive regulation of JAK-STAT cascade; regulation of developmental pigmentation; mast cell differentiation; melanocyte differentiation; germ cell programmed cell death; regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat1 protein; mast cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein; protein autophosphorylation; peptidyl-tyr | |
| KITLG | signal transduction; positive regulation of mast cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of Ras protein signal transduction; positive regulation of DNA replication; positive regulation of melanocyte differentiation; positive regulation of MAP kinase activity; negative regulation of apoptotic process; germ cell programmed cell death; cell adhesion; positive regulation of myeloid leukocyte differentiation; neural crest cell migration; ovarian follicle development; cell proliferation; positive regulation of cell proliferation; male gonad development; hemopoiesis; negative regulation of mast cell apoptosis; embryonic hemopoiesis | |
| KL | fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; energy reserve metabolic process; aging; carbohydrate metabolic process; acute inflammatory response; positive regulation of bone mineralization | |
| KLB | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of cell proliferation; carbohydrate metabolic process | |
| KLC1 | stress granule disassembly; blood coagulation; microtubule-based movement | |
| KLC3 | metabolic process | |
| KLC4 | - | |
| KLF12 | positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter | |
| KLF3 | multicellular organismal development; regulation of transcription, DNA-dependent | |
| KLF5 | positive regulation of transcription, DNA-dependent; microvillus assembly; positive regulation of cell proliferation; transcription from RNA polymerase II promoter; angiogenesis | |
| KLF8 | regulation of transcription, DNA-dependent | |
| KLF9 | cellular response to thyroid hormone stimulus; progesterone receptor signaling pathway; embryo implantation; regulation of transcription from RNA polymerase II promoter | |
| KLHDC1 | - | |
| KLHDC2 | - | |
| KLHDC7A | - | |
| KLHDC7B | - | |
| KLHDC9 | - | |
| KLHL1 | dendrite development; locomotory behavior; adult walking behavior; cerebellar Purkinje cell layer development; actin cytoskeleton organization | |
| KLHL10 | homeostasis of number of cells within a tissue; male genitalia morphogenesis; fertilization; male gonad development; spermatid development; cell morphogenesis | |
| KLHL11 | - | |
| KLHL12 | Wnt receptor signaling pathway | |
| KLHL13 | protein ubiquitination; cytokinesis; cell cycle; mitosis | |
| KLHL14 | - | |
| KLHL15 | - | |
| KLHL17 | brain development; actin cytoskeleton organization | |
| KLHL18 | - | |
| KLHL2 | intracellular protein transport | |
| KLHL20 | response to interferon-alpha; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; negative regulation of apoptotic process; cytoskeleton organization | |
| KLHL24 | - | |
| KLHL25 | - | |
| KLHL31 | regulation of transcription, DNA-dependent | |
| KLHL34 | - | |
| KLHL36 | - | |
| KLHL38 | - | |
| KLHL4 | - | |
| KLHL41 | - | |
| KLHL42 | - | |
| KLHL5 | - | |
| KLHL8 | - | |
| KLHL9 | protein ubiquitination; cell cycle; cytokinesis; mitosis | |
| KLK12 | proteolysis | |
| KLK13 | proteolysis; protein processing | |
| KLK14 | epidermis morphogenesis; proteolysis; fertilization; negative regulation of G-protein coupled receptor protein signaling pathway; positive regulation of G-protein coupled receptor protein signaling pathway; seminal clot liquefaction | |
| KLK3 | negative regulation of angiogenesis; proteolysis | |
| KLK5 | epidermis development; positive regulation of G-protein coupled receptor protein signaling pathway; proteolysis | |
| KLK6 | myelination; proteolysis; central nervous system development; response to wounding; protein autoprocessing; collagen catabolic process; tissue regeneration; hormone metabolic process; positive regulation of G-protein coupled receptor protein signaling pathway; regulation of cell differentiation; amyloid precursor protein metabolic process | |
| KLK7 | epidermis development; proteolysis | |
| KLK8 | neuron projection morphogenesis; negative regulation of axon regeneration; memory; regulation of synapse organization; keratinocyte proliferation; negative regulation of myelination; response to wounding; cell death; proteolysis | |
| KLK9 | proteolysis | |
| KLKB1 | Factor XII activation; zymogen activation; proteolysis; inflammatory response; blood coagulation; blood coagulation, intrinsic pathway; plasminogen activation; positive regulation of fibrinolysis | |
| KLRD1 | regulation of immune response; cell surface receptor signaling pathway | |
| KLRG1 | innate immune response; regulation of immune response; cellular defense response; cell surface receptor signaling pathway; inflammatory response | |
| KMT2A | - | |
| KMT2C | - | |
| KMT2E | - | |
| KMT5A | peptidyl-lysine monomethylation; negative regulation of transcription from RNA polymerase II promoter; cell cycle; mitosis; cell division; chromatin modification; negative regulation of transcription, DNA-dependent; regulation of DNA damage response, signal transduction by p53 class mediator; histone lysine methylation | |
| KMT5B | peptidyl-lysine methylation; chromatin modification; regulation of transcription, DNA-dependent; histone lysine methylation | |
| KMT5C | peptidyl-lysine methylation; histone methylation; chromatin modification; regulation of transcription, DNA-dependent | |
| KNDC1 | regulation of small GTPase mediated signal transduction; cerebellar granule cell differentiation; protein phosphorylation; regulation of dendrite morphogenesis; regulation of catalytic activity | |
| KNG1 | platelet activation; positive regulation of apoptotic process; vasodilation; positive regulation of renal sodium excretion; positive regulation of urine volume; negative regulation of blood coagulation; blood coagulation, intrinsic pathway; blood coagulation; elevation of cytosolic calcium ion concentration; negative regulation of cell adhesion; inflammatory response; smooth muscle contraction; platelet degranulation | |
| KPNA6 | NLS-bearing substrate import into nucleus | |
| KPRP | - | |
| KPTN | cellular component movement; sensory perception of sound; actin filament organization | |
| KRAS | insulin receptor signaling pathway; visual learning; fibroblast growth factor receptor signaling pathway; positive regulation of gene expression; cytokine-mediated signaling pathway; actin cytoskeleton organization; regulation of synaptic transmission, GABAergic; positive regulation of Rac protein signal transduction; social behavior; positive regulation of MAP kinase activity; negative regulation of neuron apoptosis; positive regulation of cell proliferation; blood coagulation; axon guidance; Ras protein signal transduction; small GTPase mediated signal transduction; epidermal growth factor receptor signaling pathway; signal transduction; positive regulation of protein phosphorylation; activation of MAPKK activity; MAPK cascade; leukocyte migration; regulation of long-term neuronal synaptic plasticity; nerve growth factor receptor signaling pathway; positive regulation of nitric-oxide synthase activity; positive regulation of NF-kappaB transcription factor activity; striated muscle cell differentiation; resp | |
| KRI1 | - | |
| KRIT1 | negative regulation of endothelial cell migration; negative regulation of endothelial cell apoptosis; regulation of establishment of cell polarity; cell redox homeostasis; positive regulation of protein binding; negative regulation of angiogenesis; small GTPase mediated signal transduction; negative regulation of endothelial cell proliferation | |
| KRR1 | rRNA processing | |
| KRT1 | regulation of angiogenesis; fibrinolysis; epidermis development; response to oxidative stress; complement activation, lectin pathway | |
| KRT10 | cellular response to calcium ion; keratinocyte differentiation; epidermis development | |
| KRT13 | tongue morphogenesis; cellular response to retinoic acid; response to radiation; epidermis development | |
| KRT15 | epidermis development | |
| KRT18 | interspecies interaction between organisms; negative regulation of apoptotic process; Golgi to plasma membrane CFTR protein transport; tumor necrosis factor-mediated signaling pathway; anatomical structure morphogenesis; cell cycle | |
| KRT19 | cell differentiation involved in embryonic placenta development; response to estrogen stimulus; interspecies interaction between organisms; sarcomere organization | |
| KRT2 | keratinocyte proliferation; keratinocyte migration; epidermis development; keratinization; keratinocyte activation | |
| KRT23 | - | |
| KRT24 | - | |
| KRT25 | intermediate filament organization; hair follicle morphogenesis | |
| KRT26 | - | |
| KRT27 | hair follicle morphogenesis | |
| KRT28 | - | |
| KRT32 | epidermis development | |
| KRT34 | epidermis development | |
| KRT36 | regulation of keratinocyte differentiation | |
| KRT4 | cytoskeleton organization; epithelial cell differentiation; negative regulation of epithelial cell proliferation | |
| KRT40 | - | |
| KRT5 | epidermis development; hemidesmosome assembly; cell junction assembly | |
| KRT71 | hair follicle morphogenesis | |
| KRT72 | - | |
| KRT73 | - | |
| KRT74 | - | |
| KRT75 | - | |
| KRT78 | - | |
| KRT79 | - | |
| KRT80 | - | |
| KRT83 | epidermis development | |
| KRT84 | hair follicle development; nail development; regulation of keratinocyte differentiation | |
| KRT85 | epidermis development | |
| KRT9 | spermatogenesis; epidermis development; skin development; intermediate filament organization | |
| KRTAP1-5 | - | |
| KRTAP11-1 | - | |
| KRTAP12-3 | - | |
| KRTAP13-3 | - | |
| KRTAP13-4 | - | |
| KRTAP24-1 | - | |
| KRTAP27-1 | - | |
| KRTAP3-1 | - | |
| KRTAP4-3 | - | |
| KRTCAP2 | - | |
| KRTDAP | cell differentiation | |
| KTN1 | microtubule-based movement | |
| L1CAM | heterophilic cell-cell adhesion; positive regulation of calcium-mediated signaling; multicellular organismal development; cell surface receptor signaling pathway; leukocyte cell-cell adhesion; homophilic cell adhesion; cell adhesion; chemotaxis; nervous system development; axon guidance; cell death; homotypic cell-cell adhesion; cell-cell adhesion mediated by integrin; leukocyte migration; neuron projection development; cell differentiation; positive regulation of cell-cell adhesion; blood coagulation | |
| L3HYPDH | - | |
| L3MBTL2 | regulation of transcription, DNA-dependent; chromatin modification | |
| L3MBTL3 | regulation of transcription, DNA-dependent; chromatin modification | |
| L3MBTL4 | chromatin modification | |
| LACC1 | - | |
| LACE1 | - | |
| LACRT | positive regulation of secretion; tear secretion; positive regulation of NFAT protein import into nucleus; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of epithelial cell proliferation; protein localization in Golgi apparatus; positive regulation of cell proliferation; calcium-mediated signaling; calcineurin-NFAT signaling cascade | |
| LAD1 | - | |
| LAIR1 | - | |
| LALBA | signal transduction; induction of apoptosis; cell-cell signaling; defense response to bacterium; lactose biosynthetic process | |
| LAMA1 | retinal blood vessel morphogenesis; branching involved in salivary gland morphogenesis; regulation of cell adhesion; tissue development; epithelial tube branching involved in lung morphogenesis; retina development in camera-type eye; regulation of embryonic development; axon guidance; regulation of cell migration; morphogenesis of an epithelial sheet; cell surface receptor signaling pathway; establishment of epithelial cell apical/basal polarity; neuron projection development | |
| LAMA2 | muscle organ development; regulation of cell adhesion; regulation of cell migration; positive regulation of synaptic transmission, cholinergic; regulation of embryonic development | |
| LAMA3 | epidermis development; regulation of cell adhesion; regulation of cell migration; hemidesmosome assembly; cell junction assembly; regulation of embryonic development | |
| LAMA4 | regulation of cell migration; brown fat cell differentiation; regulation of embryonic development; regulation of cell adhesion; blood vessel development | |
| LAMA5 | cell migration; regulation of cell adhesion; cell differentiation; lung development; regulation of cell migration; substrate adhesion-dependent cell spreading; regulation of cell proliferation; cilium assembly; odontogenesis of dentin-containing tooth; endothelial cell differentiation; regulation of embryonic development; focal adhesion assembly; branching involved in salivary gland morphogenesis; establishment of protein localization in plasma membrane; organ morphogenesis; morphogenesis of embryonic epithelium; angiogenesis; branching involved in ureteric bud morphogenesis; morphogenesis of a polarized epithelium; neural crest cell migration; hair follicle development; cytoskeleton organization; integrin-mediated signaling pathway; muscle organ development; cell recognition; cell proliferation; embryo development | |
| LAMB1 | positive regulation of epithelial cell proliferation; cell adhesion; odontogenesis; substrate adhesion-dependent cell spreading; neuron projection development; positive regulation of cell migration; embryo implantation; axon guidance; negative regulation of cell adhesion | |
| LAMB2 | neuron projection development; metanephric glomerular basement membrane development; metanephric glomerular visceral epithelial cell development; retina development in camera-type eye; axon extension involved in regeneration; Schwann cell development; astrocyte development; visual perception; neuromuscular junction development; cell adhesion; cell morphogenesis involved in differentiation | |
| LAMB3 | cell adhesion; epidermis development; hemidesmosome assembly; cell junction assembly; brown fat cell differentiation | |
| LAMB4 | cell adhesion | |
| LAMC1 | substrate adhesion-dependent cell spreading; positive regulation of epithelial cell proliferation; hemidesmosome assembly; neuron projection development; extracellular matrix disassembly; cell migration; axon guidance; cell adhesion; protein complex assembly; endoderm development | |
| LAMC2 | cell adhesion; epidermis development; hemidesmosome assembly; cell junction assembly | |
| LAMC3 | astrocyte development; cell morphogenesis involved in differentiation; cell adhesion; visual perception; retina development in camera-type eye | |
| LAMP2 | platelet degranulation; platelet activation; blood coagulation | |
| LAMP3 | cell proliferation | |
| LANCL1 | G-protein coupled receptor signaling pathway | |
| LANCL2 | positive regulation of abscisic acid mediated signaling pathway; negative regulation of transcription, DNA-dependent | |
| LANCL3 | - | |
| LAP3 | metabolic process; proteolysis | |
| LAPTM4A | transport | |
| LARP1 | - | |
| LARP4 | cytoskeleton organization; regulation of cell morphogenesis | |
| LARP4B | - | |
| LARP6 | RNA processing; regulation of translation | |
| LARS | gene expression; leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| LARS2 | gene expression; leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| LAS1L | rRNA processing | |
| LAT2 | calcium-mediated signaling; intracellular signal transduction; B cell activation; mast cell degranulation; B cell receptor signaling pathway | |
| LATS1 | cell division; cytoplasmic sequestering of protein; G2/M transition of mitotic cell cycle; hormone-mediated signaling pathway; regulation of actin filament polymerization; positive regulation of peptidyl-serine phosphorylation; hippo signaling cascade; regulation of protein complex assembly; mitosis; cell cycle; protein phosphorylation; sister chromatid segregation; negative regulation of cyclin-dependent protein kinase activity; negative regulation of canonical Wnt receptor signaling pathway | |
| LATS2 | keratinocyte differentiation; hormone-mediated signaling pathway; intracellular protein kinase cascade; mitosis; cell cycle; protein phosphorylation; G1/S transition of mitotic cell cycle; cellular protein localization; hippo signaling cascade; negative regulation of cyclin-dependent protein kinase activity; regulation of organ growth; cell division; negative regulation of canonical Wnt receptor signaling pathway | |
| LAYN | - | |
| LBHD1 | - | |
| LBP | opsonization; Toll signaling pathway; lipopolysaccharide transport; lipopolysaccharide-mediated signaling pathway; detection of molecule of bacterial origin; response to lipopolysaccharide; negative regulation of tumor necrosis factor production; positive regulation of chemokine production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of tumor necrosis factor production; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of macrophage activation; negative regulation of growth of symbiont in host; innate immune response; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; positive regulation of respiratory burst involved in inflammatory response; cellular response to lipopolysaccharide; cellular response to lipoteichoic acid; positive regulation of neutrophil chemotaxis; macrophage activation involved in | |
| LBR | oxidation-reduction process; small molecule metabolic process; cholesterol biosynthetic process | |
| LCA5 | protein transport | |
| LCK | platelet activation; hemopoiesis; peptidyl-tyrosine phosphorylation; viral reproduction; response to zinc ion; response to mechanical stimulus; blood coagulation; regulation of defense response to virus by virus; positive regulation of uterine smooth muscle contraction; regulation of lymphocyte activation; release of sequestered calcium ion into cytosol; leukocyte migration; positive regulation of T cell activation; positive regulation of T cell receptor signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; T cell differentiation; protein autophosphorylation; positive regulation of gamma-delta T cell differentiation; interspecies interaction between organisms; response to hydrogen peroxide; positive regulation of tyrosine phosphorylation of Stat5 protein; response to drug; peptidyl-tyrosine dephosphorylation; T cell costimulation; cell surface receptor signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; | |
| LCLAT1 | phospholipid biosynthetic process; metabolic process; multicellular organismal development | |
| LCNL1 | - | |
| LCOR | negative regulation of transcription from RNA polymerase II promoter | |
| LCP1 | T cell activation involved in immune response; organ regeneration; regulation of intracellular protein transport; actin filament bundle assembly | |
| LCT | response to sucrose stimulus; response to hypoxia; carbohydrate metabolic process; response to nutrient; response to hormone stimulus; response to nickel cation; response to lead ion; response to drug; response to starvation; response to estrogen stimulus; polysaccharide digestion; small molecule metabolic process; response to ethanol | |
| LCTL | carbohydrate metabolic process | |
| LDB1 | histone H3-K4 acetylation; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; gastrulation with mouth forming second; hair follicle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; cellular component assembly; cerebellum development; neuron differentiation; anterior/posterior axis specification; epithelial structure maintenance; Wnt receptor signaling pathway; somatic stem cell maintenance; negative regulation of erythrocyte differentiation; positive regulation of cell adhesion; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of hemoglobin biosynthetic process; head development; regulation of transcription elongation, DNA-dependent; cerebellar Purkinje cell differentiation | |
| LDB2 | positive regulation of cellular component biogenesis; epithelial structure maintenance; somatic stem cell maintenance; positive regulation of transcription from RNA polymerase II promoter; hair follicle development | |
| LDB3 | - | |
| LDHA | small molecule metabolic process; pyruvate metabolic process; glycolysis; cellular carbohydrate metabolic process | |
| LDHAL6A | glycolysis; cellular carbohydrate metabolic process | |
| LDHC | cellular carbohydrate metabolic process; glycolysis | |
| LDLR | regulation of phosphatidylcholine catabolic process; lipid metabolic process; transport; endocytosis; receptor-mediated endocytosis; steroid metabolic process; cholesterol metabolic process; positive regulation of triglyceride biosynthetic process; phospholipid transport; intestinal cholesterol absorption; cholesterol transport; low-density lipoprotein particle clearance; lipoprotein metabolic process; cholesterol homeostasis; small molecule metabolic process; interspecies interaction between organisms; cholesterol import | |
| LDLRAD2 | - | |
| LDLRAD3 | - | |
| LDLRAD4 | - | |
| LDLRAP1 | cholesterol metabolic process; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of establishment of protein localization in plasma membrane; positive regulation of receptor-mediated endocytosis; positive regulation of cholesterol metabolic process; regulation of protein binding; amyloid precursor protein metabolic process; transport; cholesterol homeostasis; receptor internalization; positive regulation of signal transduction; steroid metabolic process; receptor-mediated endocytosis | |
| LEAP2 | defense response to bacterium | |
| LECT1 | multicellular organismal development; endothelial cell morphogenesis; negative regulation of endothelial cell proliferation; negative regulation of angiogenesis; cell differentiation; negative regulation of vascular endothelial growth factor receptor signaling pathway; proteoglycan metabolic process; cartilage development; skeletal system development | |
| LEF1 | mammary gland development; formation of radial glial scaffolds; neurogenesis; forebrain neuron differentiation; forebrain neuroblast division; forebrain radial glial cell differentiation; hypothalamus development; skin development; dentate gyrus development; organ regeneration; negative regulation of interleukin-13 production; negative regulation of interleukin-4 production; negative regulation of interleukin-5 production; T cell receptor V(D)J recombination; B cell proliferation; odontogenesis of dentin-containing tooth; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of DNA binding; tongue development; positive regulation of cell cycle process; brain development; negative regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; osteoblast differentiation; neural crest cell migration; somitogenesis; kidney development; epithelial to mesenchymal transition; vasculature deve | |
| LEMD2 | skeletal muscle cell differentiation | |
| LEMD3 | negative regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of activin receptor signaling pathway | |
| LENG8 | - | |
| LENG9 | RNA metabolic process | |
| LEO1 | histone monoubiquitination; histone H2B ubiquitination; regulation of transcription, DNA-dependent | |
| LEPR | energy reserve metabolic process; negative regulation of hydrolase activity; cholesterol metabolic process; multicellular organismal development; cell surface receptor signaling pathway | |
| LETM1 | cristae formation | |
| LETM2 | - | |
| LFNG | ovarian follicle development; female meiosis; compartment pattern specification; pattern specification process; organ morphogenesis | |
| LGALS1 | signal transduction; apoptotic process; negative regulation of neuron projection development; cellular response to organic cyclic compound; cellular response to glucose stimulus; response to axon injury; myoblast differentiation; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; response to drug; positive regulation of erythrocyte aggregation; multicellular organismal response to stress; negative regulation of cell-substrate adhesion | |
| LGALS3BP | cellular defense response; signal transduction; cell adhesion | |
| LGALS8 | - | |
| LGI2 | - | |
| LGI3 | regulation of exocytosis | |
| LGR4 | negative regulation of transcription, DNA-dependent; G-protein coupled receptor signaling pathway; tube morphogenesis; male genitalia development; metanephric glomerulus development; cell differentiation involved in metanephros development; canonical Wnt receptor signaling pathway involved in metanephric kidney development; epithelial cell proliferation; positive regulation of transcription, DNA-dependent; metanephric nephron tubule morphogenesis; positive regulation of branching involved in ureteric bud morphogenesis | |
| LGR5 | G-protein coupled receptor signaling pathway | |
| LGSN | glutamine biosynthetic process; nitrogen compound metabolic process | |
| LHCGR | ovarian follicle development; protein targeting to lysosome; G-protein coupled receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to cAMP nucleotide second messenger; activation of adenylate cyclase activity; spermatogenesis; regulation of steroid hormone biosynthetic process; seminiferous tubule development; uterus development; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of calcium-mediated signaling; arachidonic acid secretion; positive regulation of hormone biosynthetic process; development of secondary male sexual characteristics; response to drug; male genitalia development; hormone-mediated signaling pathway; male gonad development; central nervous system development; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger | |
| LHFP | - | |
| LHFPL1 | - | |
| LHFPL4 | - | |
| LHFPL5 | sensory perception of sound; auditory receptor cell stereocilium organization | |
| LHPP | protein dephosphorylation; metabolic process; phosphate-containing compound metabolic process | |
| LHX1 | cellular response to fibroblast growth factor stimulus; regulation of gene expression; negative regulation of transcription, DNA-dependent; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; metanephric comma-shaped body morphogenesis; retina layer formation; ventral spinal cord development; spinal cord association neuron differentiation; telencephalon development; cerebellum development; cerebellar Purkinje cell differentiation; forebrain regionalization; positive regulation of embryonic development; cell differentiation; somite rostral/caudal axis specification; metanephric ureteric bud development; oviduct epithelium development; uterine epithelium development; nephric duct elongation; horizontal cell localization; vagina development; metanephric glomerulus development; nephric duct morphogenesis; mesonephric duct development; renal vesicle morphogenesis; S-shaped body morphogenesis; comma-shaped body morphogenesis; paramesone | |
| LHX2 | anatomical structure formation involved in morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; mesoderm development; negative regulation of transcription regulatory region DNA binding; neuron differentiation; telencephalon regionalization; dorsal/ventral pattern formation; brain development; axon guidance; neural tube closure; neurogenesis | |
| LHX3 | organ morphogenesis; positive regulation of transcription, DNA-dependent; inner ear development | |
| LHX5 | regulation of cell proliferation; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; forebrain neuron differentiation; positive regulation of transcription, DNA-dependent; spinal cord association neuron differentiation; cerebellum development; cerebellar Purkinje cell differentiation; cell proliferation in forebrain; hippocampus development | |
| LHX6 | multicellular organismal development; cell maturation; cell differentiation; cerebral cortex neuron differentiation; forebrain neuron development; forebrain neuron fate commitment; regulation of transcription, DNA-dependent; cerebral cortex GABAergic interneuron migration; cerebral cortex tangential migration; nervous system development; cerebral cortex radially oriented cell migration | |
| LHX8 | odontogenesis of dentin-containing tooth; forebrain neuron development; female gonad development; learning or memory | |
| LHX9 | negative regulation of transcription, DNA-dependent; gonad morphogenesis; female gonad development; motor axon guidance; cell proliferation; male gonad development | |
| LIAS | neural tube closure; inflammatory response; response to oxidative stress; lipoate biosynthetic process; response to lipopolysaccharide | |
| LIF | positive regulation of peptidyl-serine phosphorylation; lung alveolus development; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of MAPK cascade; regulation of cell differentiation; positive regulation of macrophage differentiation; negative regulation of meiosis; positive regulation of transcription from RNA polymerase II promoter; decidualization; transdifferentiation; muscle organ morphogenesis; neuron development; positive regulation of astrocyte differentiation; leukemia inhibitory factor signaling pathway; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of corticotropin secretion; retina development in camera-type eye; maternal process involved in female pregnancy; regulation of metanephric nephron tubule epithelial cell differentiation; lung vasculature development; lung lobe morphogenesis; trophob | |
| LIFR | cell surface receptor signaling pathway; positive regulation of cell proliferation; cytokine-mediated signaling pathway; ciliary neurotrophic factor-mediated signaling pathway; organ regeneration; response to cytokine stimulus; response to chemical stimulus; positive regulation of anti-apoptosis; neuron projection morphogenesis; leukemia inhibitory factor signaling pathway | |
| LIG1 | telomere maintenance via recombination; telomere maintenance; S phase of mitotic cell cycle; double-strand break repair via homologous recombination; DNA metabolic process; DNA replication; DNA ligation; DNA strand elongation involved in DNA replication; DNA repair; transcription-coupled nucleotide-excision repair; base-excision repair; nucleotide-excision repair; nucleotide-excision repair, DNA gap filling; double-strand break repair; DNA recombination; anatomical structure morphogenesis; telomere maintenance via semi-conservative replication; V(D)J recombination; DNA ligation involved in DNA repair; cell division; mitotic cell cycle | |
| LIG3 | V(D)J recombination; DNA replication; DNA ligation; DNA repair; base-excision repair; DNA recombination; cell cycle; reciprocal meiotic recombination; spermatogenesis; DNA ligation involved in DNA repair; cell division | |
| LIG4 | cellular response to lithium ion; response to X-ray; cell proliferation; central nervous system development; cell cycle; double-strand break repair via nonhomologous end joining; double-strand break repair; somatic stem cell maintenance; positive regulation of neurogenesis; response to gamma radiation; viral reproduction; provirus integration; initiation of viral infection; T cell differentiation in thymus; V(D)J recombination; T cell receptor V(D)J recombination; neuron apoptosis; negative regulation of neuron apoptosis; isotype switching; positive regulation of fibroblast proliferation; DNA ligation involved in DNA recombination; DNA ligation involved in DNA repair; chromosome organization; cell division; DNA repair; nucleotide-excision repair, DNA gap filling; single strand break repair; in utero embryonic development; pro-B cell differentiation; DNA replication; DNA ligation | |
| LILRA5 | innate immune response | |
| LILRB4 | signal transduction; negative regulation of osteoclast differentiation | |
| LIM2 | cell-cell junction assembly; lens development in camera-type eye | |
| LIMCH1 | actomyosin structure organization | |
| LIMD1 | multicellular organismal development; regulation of transcription, DNA-dependent; cytoskeleton organization; signal transduction; regulation of cell shape; cell migration; cytoplasmic mRNA processing body assembly; gene silencing by miRNA; negative regulation of transcription, DNA-dependent | |
| LIMK2 | regulation of phosphorylation; phosphorylation; spermatogenesis | |
| LIN54 | mitotic cell cycle; regulation of transcription, DNA-dependent | |
| LIN9 | mitotic cell cycle; DNA replication | |
| LINC01565 | - | |
| LINGO2 | - | |
| LINGO4 | - | |
| LINS1 | - | |
| LIPE | protein phosphorylation; lipid metabolic process; female pregnancy; steroid metabolic process; cholesterol metabolic process; lipid catabolic process; triglyceride catabolic process; response to drug; small molecule metabolic process; diacylglycerol catabolic process | |
| LIPF | lipid catabolic process; triglyceride metabolic process | |
| LIPG | positive regulation of cholesterol transport; high-density lipoprotein particle remodeling; cholesterol homeostasis; reverse cholesterol transport; regulation of lipoprotein metabolic process; phospholipid homeostasis; positive regulation of high-density lipoprotein particle clearance; cell proliferation; phospholipid catabolic process; lipid catabolic process; response to nutrient; lipid metabolic process | |
| LIPH | lipid catabolic process | |
| LIPI | lipid catabolic process | |
| LIPJ | lipid catabolic process | |
| LKAAEAR1 | - | |
| LLGL1 | maintenance of apical/basal cell polarity; protein complex assembly; exocytosis; cortical actin cytoskeleton organization | |
| LLGL2 | exocytosis; cell cycle; regulation of establishment or maintenance of cell polarity; cell division | |
| LLPH | - | |
| LMAN1 | post-translational protein modification; protein folding; cellular protein metabolic process; early endosome to Golgi transport; protein exit from endoplasmic reticulum; protein N-linked glycosylation via asparagine; vesicle-mediated transport; protein transport; positive regulation of organelle organization; blood coagulation; Golgi organization; ER to Golgi vesicle-mediated transport | |
| LMAN2 | protein transport | |
| LMAN2L | protein folding; protein transport; ER to Golgi vesicle-mediated transport | |
| LMBR1 | embryonic digit morphogenesis | |
| LMBR1L | endocytosis | |
| LMBRD2 | - | |
| LMCD1 | regulation of cardiac muscle hypertrophy; positive regulation of calcineurin-NFAT signaling cascade; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| LMF2 | - | |
| LMNA | protein localization to nucleus; sterol regulatory element binding protein import into nucleus; endoplasmic reticulum unfolded protein response; establishment or maintenance of microtubule cytoskeleton polarity; regulation of cell migration; muscle organ development; spermatogenesis; nuclear envelope organization; activation of signaling protein activity involved in unfolded protein response; cellular component disassembly involved in apoptosis; apoptotic process; regulation of apoptotic process; ventricular cardiac muscle cell development; cellular response to hypoxia; positive regulation of cell aging | |
| LMNB1 | cellular component disassembly involved in apoptosis; apoptotic process | |
| LMNB2 | - | |
| LMNTD1 | cell proliferation | |
| LMO7 | protein ubiquitination | |
| LMTK2 | peptidyl-serine phosphorylation; protein autophosphorylation; early endosome to late endosome transport; transferrin transport; endocytic recycling; peptidyl-threonine phosphorylation; protein phosphorylation; receptor recycling | |
| LNP1 | - | |
| LNPEP | antigen processing and presentation of exogenous peptide antigen via MHC class I; protein catabolic process; female pregnancy; cell-cell signaling; proteolysis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; antigen processing and presentation of peptide antigen via MHC class I; protein polyubiquitination | |
| LNX1 | protein homooligomerization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| LNX2 | protein homooligomerization | |
| LOC81691 | - | |
| LONP1 | protein homooligomerization; mitochondrial genome maintenance; response to hypoxia; misfolded or incompletely synthesized protein catabolic process; mitochondrion organization; mitochondrial DNA metabolic process; oxidation-dependent protein catabolic process; proteolysis involved in cellular protein catabolic process; cellular response to oxidative stress | |
| LONP2 | protein targeting to peroxisome; peroxisome organization; misfolded or incompletely synthesized protein catabolic process; proteolysis; response to organic cyclic compound; regulation of fatty acid beta-oxidation; signal peptide processing | |
| LONRF1 | proteolysis | |
| LONRF2 | proteolysis | |
| LOXL3 | oxidation-reduction process | |
| LOXL4 | - | |
| LPA | lipoprotein metabolic process; proteolysis; lipid metabolic process; transport; lipid transport; receptor-mediated endocytosis; small molecule metabolic process; blood circulation; negative regulation of endopeptidase activity | |
| LPAR1 | positive regulation of cell death; activation of MAPK activity; G-protein coupled receptor signaling pathway; activation of phospholipase C activity; elevation of cytosolic calcium ion concentration; negative regulation of neuron projection development; positive regulation of smooth muscle cell chemotaxis; cellular response to oxygen levels; positive regulation of dendritic spine development; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; positive regulation of MAPK cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; myelination; positive regulation of Rho protein signal transduction; bleb assembly; neurogenesis | |
| LPAR2 | positive regulation of MAPK cascade; positive regulation of Rho protein signal transduction; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity; G-protein coupled receptor signaling pathway; activation of MAPK activity | |
| LPAR4 | G-protein coupled receptor signaling pathway | |
| LPAR6 | G-protein coupled receptor signaling pathway | |
| LPCAT1 | metabolic process; phospholipid biosynthetic process; retina development in camera-type eye | |
| LPCAT3 | phospholipid biosynthetic process | |
| LPCAT4 | phospholipid biosynthetic process; metabolic process | |
| LPIN1 | small molecule metabolic process; cellular lipid metabolic process; cellular response to insulin stimulus; triglyceride mobilization; organ regeneration; triglyceride biosynthetic process; regulation of transcription, DNA-dependent; fatty acid catabolic process | |
| LPIN3 | dephosphorylation; fatty acid metabolic process; lipid metabolic process | |
| LPO | response to oxidative stress; hydrogen peroxide catabolic process | |
| LRBA | - | |
| LRCH1 | - | |
| LRCH3 | - | |
| LRCH4 | nervous system development; negative regulation of transcription, DNA-dependent | |
| LRFN2 | - | |
| LRFN3 | cell adhesion | |
| LRFN4 | - | |
| LRFN5 | - | |
| LRG1 | brown fat cell differentiation | |
| LRGUK | - | |
| LRIF1 | regulation of transcription, DNA-dependent | |
| LRIG1 | - | |
| LRIG2 | - | |
| LRIT1 | - | |
| LRIT2 | - | |
| LRIT3 | - | |
| LRP1 | negative regulation of Wnt receptor signaling pathway; regulation of actin cytoskeleton organization; regulation of phospholipase A2 activity; regulation of cholesterol transport; positive regulation of lipid transport; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; aorta morphogenesis; lipoprotein metabolic process; lipoprotein transport; apoptotic cell clearance; positive regulation of anti-apoptosis; positive regulation of protein transport; negative regulation of smooth muscle cell migration; positive regulation of cholesterol efflux; cell proliferation; aging; multicellular organismal development; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; receptor-mediated endocytosis | |
| LRP10 | lipid transport; endocytosis; lipid metabolic process | |
| LRP12 | endocytosis; signal transduction; regulation of growth | |
| LRP1B | protein transport; receptor-mediated endocytosis | |
| LRP2 | lipid metabolic process; vitamin metabolic process; endocytosis; receptor-mediated endocytosis; steroid metabolic process; protein glycosylation; cell proliferation; forebrain development; vitamin D metabolic process; small molecule metabolic process | |
| LRP3 | receptor-mediated endocytosis | |
| LRP4 | negative regulation of ossification; cell differentiation; proximal/distal pattern formation; synaptic growth at neuromuscular junction; dorsal/ventral pattern formation; odontogenesis of dentin-containing tooth; embryonic digit morphogenesis; receptor clustering; anatomical structure development; protein localization; multicellular organismal development; endocytosis; hair follicle development; kidney development; negative regulation of canonical Wnt receptor signaling pathway | |
| LRP5 | embryonic limb morphogenesis; Wnt receptor signaling pathway; negative regulation of osteoblast differentiation; anterior/posterior pattern specification; cholesterol homeostasis; Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of fat cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of cell proliferation; regulation of blood pressure; multicellular organismal development; endocytosis; glucose catabolic process; osteoblast development; positive regulation of mesenchymal cell proliferation; gastrulation with mouth forming second; positive regulation of transcription, DNA-dependent; positive regulation of mitosis; regulation of canonical Wnt receptor signaling pathway; negative regulation of protein serine/threonine kinase activity; retinal blood vessel morphogenesis; adipose tissue development; branching involved in mammary gland duct morphogenesis; bone morphogenesis; embryonic retina m | |
| LRP6 | negative regulation of protein serine/threonine kinase activity; dopaminergic neuron differentiation; cellular response to cholesterol; canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; mammary placode formation; trachea cartilage morphogenesis; branching involved in mammary gland duct morphogenesis; bone morphogenesis; face morphogenesis; regulation of cell development; canonical Wnt receptor signaling pathway; embryonic retina morphogenesis in camera-type eye; primitive streak formation; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; Wnt receptor signaling pathway involved in somitogenesis; axis elongation involved in somitogenesis; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of Wnt receptor signaling pathway involved in do | |
| LRPPRC | mitochondrion transport along microtubule; mRNA transport; transport; regulation of transcription, DNA-dependent | |
| LRR1 | - | |
| LRRC1 | - | |
| LRRC14 | - | |
| LRRC15 | - | |
| LRRC16B | - | |
| LRRC17 | osteoblast differentiation; osteoblast proliferation; bone marrow development; negative regulation of osteoclast differentiation | |
| LRRC18 | - | |
| LRRC19 | - | |
| LRRC2 | - | |
| LRRC23 | - | |
| LRRC25 | - | |
| LRRC28 | - | |
| LRRC3 | - | |
| LRRC30 | - | |
| LRRC32 | - | |
| LRRC34 | - | |
| LRRC36 | - | |
| LRRC39 | - | |
| LRRC3B | - | |
| LRRC4 | - | |
| LRRC41 | - | |
| LRRC46 | - | |
| LRRC49 | - | |
| LRRC4B | - | |
| LRRC4C | regulation of axonogenesis | |
| LRRC52 | - | |
| LRRC6 | male gonad development; pachytene; diplotene | |
| LRRC61 | - | |
| LRRC66 | - | |
| LRRC7 | - | |
| LRRC73 | - | |
| LRRC8A | cell differentiation; pre-B cell differentiation | |
| LRRC8D | - | |
| LRRC8E | - | |
| LRRFIP1 | regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent | |
| LRRFIP2 | Wnt receptor signaling pathway | |
| LRRIQ1 | - | |
| LRRIQ3 | - | |
| LRRK1 | small GTPase mediated signal transduction | |
| LRRK2 | positive regulation of cell death; protein autophosphorylation; negative regulation of neuron maturation; MAPK cascade; negative regulation of neuroblast proliferation; activation of MAPKK activity; activation of MAPK activity; small GTPase mediated signal transduction; positive regulation of autophagy; neuromuscular junction development; response to oxidative stress; positive regulation of protein phosphorylation; determination of adult lifespan; positive regulation of GTPase activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of branching morphogenesis of a nerve; neuron death; regulation of kidney size; positive regulation of protein ubiquitination; exploration behavior; tangential migration from the subventricular zone to the olfactory bulb; olfactory bulb development; peptidyl-serine phosphorylation; negative regulation of dendritic spine morphogenesis; positive regulation of dopamine receptor signaling pathway; intracellular distribution of mit | |
| LRRN1 | - | |
| LRRN2 | signal transduction; cell adhesion | |
| LRRN3 | positive regulation of protein phosphorylation | |
| LRRN4CL | - | |
| LRRTM1 | - | |
| LRRTM3 | - | |
| LRSAM1 | ubiquitin-dependent endocytosis; protein autoubiquitination; non-lytic virus budding; negative regulation of endocytosis; protein catabolic process; protein transport; protein polyubiquitination | |
| LRTM2 | - | |
| LSAMP | cell adhesion; nervous system development | |
| LSG1 | protein transport; nuclear export | |
| LSR | liver development; embryo development; regulation of lipid metabolic process | |
| LSS | steroid biosynthetic process; cholesterol biosynthetic process; steroid metabolic process; sterol metabolic process; small molecule metabolic process | |
| LTA4H | proteolysis; prostanoid metabolic process; leukotriene biosynthetic process; inflammatory response; response to zinc ion; Type I pneumocyte differentiation; small molecule metabolic process; response to peptide hormone stimulus; peptide catabolic process | |
| LTB4R | immune response; cellular component movement; muscle contraction; inflammatory response; G-protein coupled receptor signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger | |
| LTB4R2 | keratinocyte migration; negative regulation of adenylate cyclase activity; G-protein coupled receptor signaling pathway; signal transduction; chemotaxis | |
| LTBP1 | negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta | |
| LTBP2 | protein targeting; transforming growth factor beta receptor signaling pathway; protein secretion | |
| LTBP3 | positive regulation of bone resorption; negative regulation of chondrocyte differentiation; skeletal system development; transforming growth factor beta receptor signaling pathway; negative regulation of bone mineralization; bone remodeling; bone morphogenesis; lung saccule development | |
| LTBR | apoptotic process; signal transduction; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; interspecies interaction between organisms; positive regulation of JNK cascade; cellular response to mechanical stimulus | |
| LTF | ion transport; proteolysis; defense response to bacterium; metabolic process; humoral immune response; cellular iron ion homeostasis; iron ion transport | |
| LTK | positive regulation of neuron projection development; protein phosphorylation; apoptotic process; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; cell proliferation; phosphatidylinositol 3-kinase cascade; cellular response to retinoic acid | |
| LTN1 | protein autoubiquitination | |
| LUC7L | negative regulation of striated muscle tissue development | |
| LUC7L2 | - | |
| LUM | visual perception; response to organic cyclic compound; collagen fibril organization; cartilage development; response to growth factor stimulus | |
| LURAP1L | - | |
| LUZP1 | - | |
| LUZP2 | - | |
| LUZP4 | - | |
| LY6K | - | |
| LY86 | cell proliferation; inflammatory response; humoral immune response; innate immune response; apoptotic process | |
| LY9 | immunoglobulin mediated immune response; cell adhesion | |
| LYAR | - | |
| LYG1 | cell wall macromolecule catabolic process; metabolic process; peptidoglycan catabolic process | |
| LYL1 | positive regulation of transcription, DNA-dependent; definitive hemopoiesis; blood vessel maturation; regulation of transcription, DNA-dependent; B cell differentiation | |
| LYN | negative regulation of MAP kinase activity; interspecies interaction between organisms; innate immune response; regulation of erythrocyte differentiation; protein autophosphorylation; response to axon injury; cytokine secretion; negative regulation of immune response; regulation of B cell receptor signaling pathway; leukocyte migration; positive regulation of cellular component movement; regulation of release of sequestered calcium ion into cytosol; positive regulation of glial cell proliferation; positive regulation of Fc receptor mediated stimulatory signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; positive regulation of stress-activated protein kinase signaling cascade; regulation of ERK1 and ERK2 cascade; negative regulation of ERK1 and ERK2 cascade; positive regulation of oligodendrocyte progenitor proliferation; negative regulation of mast cell proliferation; positive regulation of mast cell proliferation; cellular response to retinoic acid; regulation of monocyte chemot | |
| LYNX1 | - | |
| LYPD2 | - | |
| LYPLA1 | lipid metabolic process; nitric oxide metabolic process; small molecule metabolic process; fatty acid metabolic process; regulation of nitric-oxide synthase activity | |
| LYSMD1 | cell wall macromolecule catabolic process | |
| LYSMD2 | cell wall macromolecule catabolic process | |
| LYSMD3 | cell wall macromolecule catabolic process | |
| LYSMD4 | cell wall macromolecule catabolic process | |
| LYST | mast cell secretory granule organization; defense response to virus; pigmentation; defense response to bacterium; natural killer cell mediated cytotoxicity; endosome to lysosome transport via multivesicular body sorting pathway; melanosome organization; leukocyte chemotaxis; protein transport; defense response to protozoan | |
| LYVE1 | cell adhesion; cellular component movement; transport; glycosaminoglycan catabolic process; cell-matrix adhesion; signal transduction; response to wounding; anatomical structure morphogenesis | |
| LZIC | response to ionizing radiation | |
| LZTFL1 | - | |
| LZTR1 | regulation of transcription, DNA-dependent; anatomical structure morphogenesis | |
| LZTS1 | transcription elongation from RNA polymerase III promoter; termination of RNA polymerase III transcription; cell cycle; gene expression; regulation of dendrite morphogenesis; transcription from RNA polymerase III promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent | |
| M1AP | - | |
| M6PR | endosome to lysosome transport; receptor-mediated endocytosis; transport | |
| MAATS1 | - | |
| MAB21L1 | positive regulation of cell proliferation; multicellular organismal development; anatomical structure morphogenesis; camera-type eye development; embryonic organ development | |
| MAB21L2 | nervous system development; camera-type eye development; embryonic body morphogenesis; positive regulation of cell proliferation; multicellular organismal development | |
| MAB21L3 | - | |
| MACC1 | positive regulation of cell division; regulation of transcription, DNA-dependent | |
| MACF1 | establishment or maintenance of cell polarity; regulation of epithelial cell migration; positive regulation of Wnt receptor signaling pathway; cell cycle arrest; regulation of focal adhesion assembly; cellular component movement; Golgi to plasma membrane protein transport; regulation of microtubule-based process; posttranslational protein targeting to membrane; wound healing; mesoderm formation; ATP catabolic process | |
| MACROD2 | purine nucleoside metabolic process | |
| MAD1L1 | mitotic telophase; mitotic cell cycle checkpoint; mitotic cell cycle spindle assembly checkpoint; cell division; mitotic cell cycle; mitotic prometaphase; cell cycle checkpoint; M phase of mitotic cell cycle; mitotic anaphase; mitotic metaphase | |
| MAD2L2 | regulation of cell growth; negative regulation of mitotic anaphase-promoting complex activity; cell division; positive regulation of peptidyl-serine phosphorylation; mitotic cell cycle spindle assembly checkpoint; mitosis; negative regulation of protein catabolic process; cell cycle; double-strand break repair; DNA repair; DNA damage response, signal transduction resulting in transcription; positive regulation of transcription, DNA-dependent | |
| MADCAM1 | cell adhesion; regulation of immune response; embryo development; aging; signal transduction; immune response; positive regulation of leukocyte migration | |
| MADD | cell surface receptor signaling pathway; regulation of apoptotic process; activation of MAPK activity; positive regulation of protein phosphorylation; regulation of cell cycle | |
| MAEA | cell division; cytoskeleton organization; cell cycle; cell adhesion; regulation of mitotic cell cycle; negative regulation of myeloid cell apoptosis; erythrocyte maturation; enucleate erythrocyte development | |
| MAEL | DNA methylation involved in gamete generation; negative regulation of gene expression; fertilization; spermatogenesis; multicellular organismal development; gene silencing by RNA; male meiosis; piRNA metabolic process; synapsis; meiotic prophase I; response to DNA damage stimulus; cell morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell differentiation; regulation of organ growth; negative regulation of apoptotic process | |
| MAF | transcription from RNA polymerase II promoter | |
| MAF1 | regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase III promoter | |
| MAFA | insulin secretion; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to glucose stimulus; nitric oxide mediated signal transduction | |
| MAFB | rhombomere 6 development; brain segmentation; inner ear morphogenesis; negative regulation of erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; sensory organ development; segment specification; rhombomere 5 development; respiratory gaseous exchange | |
| MAFG | in utero embryonic development; regulation of transcription, DNA-dependent; blood coagulation; adult behavior; regulation of cellular pH; regulation of cell proliferation; regulation of epidermal cell differentiation | |
| MAG | cell adhesion; blood coagulation; nerve growth factor receptor signaling pathway; regulation of axonogenesis; negative regulation of axonogenesis; leukocyte migration | |
| MAGEA11 | - | |
| MAGEB1 | - | |
| MAGEB10 | - | |
| MAGEB16 | - | |
| MAGEB2 | - | |
| MAGEB3 | - | |
| MAGEB4 | - | |
| MAGEC1 | - | |
| MAGEC2 | - | |
| MAGEC3 | - | |
| MAGED1 | negative regulation of epithelial cell proliferation; nerve growth factor receptor signaling pathway; regulation of apoptotic process; induction of apoptosis by extracellular signals; apoptotic process; regulation of transcription, DNA-dependent | |
| MAGED2 | - | |
| MAGEE1 | - | |
| MAGEE2 | - | |
| MAGEF1 | - | |
| MAGI1 | cell surface receptor signaling pathway; cell adhesion; protein complex assembly | |
| MAGI2 | SMAD protein signal transduction; mitotic cell cycle arrest; negative regulation of protein kinase B signaling cascade; negative regulation of activin receptor signaling pathway; protein heterooligomerization; negative regulation of cell proliferation; positive regulation of phosphoprotein phosphatase activity; receptor clustering; negative regulation of cell migration; glomerular visceral epithelial cell development; planar cell polarity pathway involved in axis elongation; positive regulation of receptor internalization | |
| MAGI3 | interspecies interaction between organisms; apoptotic process; intracellular signal transduction | |
| MAGT1 | protein N-linked glycosylation; transport; magnesium ion transport; cognition | |
| MAL | apical protein localization; membrane raft polarization; induction of apoptosis; central nervous system development; cell differentiation; myelination | |
| MALT1 | positive regulation of phosphorylation; positive regulation of protein ubiquitination; protein oligomerization; nuclear export; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; T cell receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; positive regulation of interleukin-2 production; protein ubiquitination; activation of NF-kappaB-inducing kinase activity; defense response; anti-apoptosis; proteolysis; positive regulation of T cell cytokine production | |
| MAMDC2 | - | |
| MAML1 | regulation of transcription, DNA-dependent; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; myoblast differentiation; positive regulation of myotube differentiation; gene expression; Notch signaling pathway; protein phosphorylation | |
| MAMLD1 | male gonad development; regulation of transcription, DNA-dependent | |
| MAMSTR | positive regulation of myotube differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| MAN1A1 | metabolic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process | |
| MAN1A2 | N-glycan processing; respiratory gaseous exchange; metabolic process; glycoprotein metabolic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process; lung alveolus development | |
| MAN1B1 | cellular protein metabolic process; protein N-linked glycosylation via asparagine; oligosaccharide metabolic process; post-translational protein modification; ER-associated protein catabolic process; metabolic process; protein folding; protein N-linked glycosylation | |
| MAN1C1 | protein N-linked glycosylation; metabolic process; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine | |
| MAN2A1 | protein N-linked glycosylation via asparagine; in utero embryonic development; liver development; carbohydrate metabolic process; mannose metabolic process; N-glycan processing; mitochondrion organization; vacuole organization; respiratory gaseous exchange; post-translational protein modification; cellular protein metabolic process; lung alveolus development | |
| MAN2B1 | mannose metabolic process; learning or memory; protein deglycosylation; protein modification process; carbohydrate metabolic process | |
| MAN2B2 | mannose metabolic process; carbohydrate metabolic process | |
| MAN2C1 | carbohydrate metabolic process; mannose metabolic process | |
| MANBA | protein modification process; carbohydrate metabolic process | |
| MANEA | post-translational protein modification; cellular protein metabolic process; protein N-linked glycosylation via asparagine | |
| MANEAL | - | |
| MAOA | serotonin metabolic process; cellular biogenic amine metabolic process; catecholamine metabolic process; xenobiotic metabolic process; synaptic transmission; neurotransmitter secretion; behavior; neurotransmitter catabolic process; neurotransmitter biosynthetic process; dopamine catabolic process; phenylethylamine metabolic process; small molecule metabolic process | |
| MAOB | response to steroid hormone stimulus; xenobiotic metabolic process; response to toxin; response to aluminum ion; response to selenium ion; negative regulation of serotonin secretion; response to lipopolysaccharide; response to drug; small molecule metabolic process; response to ethanol; positive regulation of dopamine metabolic process; response to corticosterone stimulus | |
| MAP1A | - | |
| MAP1B | positive regulation of microtubule polymerization; establishment of monopolar cell polarity; induction of synaptic plasticity by chemical substance; response to axon injury; developmental maturation; response to mechanical stimulus; response to carbohydrate stimulus; embryo development; cellular process; response to inorganic substance; peripheral nervous system axon regeneration; dendrite development; response to insecticide; central nervous system development; response to nutrient levels; response to estradiol stimulus; negative regulation of intracellular transport; positive regulation of axon extension; positive regulation of neuron differentiation; response to vitamin A; response to peptide hormone stimulus; response to drug; synapse assembly; neuron development; mitochondrion transport along microtubule; axon extension involved in development; microtubule bundle formation; negative regulation of microtubule depolymerization; axonogenesis | |
| MAP1S | mitochondrion transport along microtubule; apoptotic process; neuron projection morphogenesis; nervous system development; brain development; microtubule bundle formation | |
| MAP2 | dendrite morphogenesis; neuron projection development; central nervous system neuron development; peptidyl-threonine phosphorylation; axonogenesis; negative regulation of microtubule depolymerization; microtubule bundle formation | |
| MAP2K1 | toll-like receptor 4 signaling pathway; nerve growth factor receptor signaling pathway; vesicle transport along microtubule; response to axon injury; positive regulation of Ras protein signal transduction; positive regulation of cell differentiation; innate immune response; TRIF-dependent toll-like receptor signaling pathway; signal transduction; neuron projection morphogenesis; cell motility; response to glucocorticoid stimulus; stress-activated MAPK cascade; placenta blood vessel development; labyrinthine layer development; regulation of Golgi inheritance; cellular senescence; axon guidance; Ras protein signal transduction; small GTPase mediated signal transduction; regulation of early endosome to late endosome transport; MAPK cascade; epidermal growth factor receptor signaling pathway; regulation of stress-activated MAPK cascade; neuron differentiation; melanosome transport; positive regulation of Ras GTPase activity; mitosis; positive regulation of cell migration; keratinocyte differentiation; cell cycle | |
| MAP2K3 | innate immune response; positive regulation of transcription, DNA-dependent; positive regulation of protein kinase activity; stress-activated MAPK cascade; cardiac muscle contraction; toll-like receptor signaling pathway; regulation of cytokine biosynthetic process; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; Toll signaling pathway; signal transduction; inflammatory response; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; activation of MAPK activity | |
| MAP2K4 | MyD88-dependent toll-like receptor signaling pathway; cellular response to mechanical stimulus; stress-activated MAPK cascade; innate immune response; toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 2 signaling pathway; MyD88-independent toll-like receptor signaling pathway; protein phosphorylation; apoptotic process; response to stress; signal transduction; JNK cascade; Toll signaling pathway; toll-like receptor 1 signaling pathway | |
| MAP2K5 | negative regulation of response to cytokine stimulus; negative regulation of chemokine (C-X-C motif) ligand 2 production; negative regulation of cell migration involved in sprouting angiogenesis; cellular response to laminar fluid shear stress; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of heterotypic cell-cell adhesion; negative regulation of NF-kappaB transcription factor activity; positive regulation of cell growth; heart development; signal transduction; protein phosphorylation; activation of MAPK activity; negative regulation of transcription from RNA polymerase II promoter; ERK5 cascade; cellular response to growth factor stimulus; positive regulation of transcription from RNA polymerase II promoter; nerve growth factor receptor signaling pathway; negative regulation of interleukin-8 biosynthetic process; positive regulation of protein metabolic process; positive regulation of epithelial cell pr | |
| MAP2K7 | MyD88-dependent toll-like receptor signaling pathway; apoptotic process; MyD88-independent toll-like receptor signaling pathway; toll-like receptor signaling pathway; activation of MAPK activity; response to stress; stress-activated MAPK cascade; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; positive regulation of neuron apoptosis; innate immune response; toll-like receptor 1 signaling pathway; Toll signaling pathway; activation of JUN kinase activity; JNK cascade; signal transduction | |
| MAP3K1 | toll-like receptor signaling pathway; protein polyubiquitination; activation of MAPKK activity; MAPK cascade; toll-like receptor 1 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; protein phosphorylation; response to osmotic stress; transforming growth factor beta receptor signaling pathway; Toll signaling pathway; apoptotic mitochondrial changes; peptidyl-serine phosphorylation; regulation of cell migration; positive regulation of actin filament polymerization; negative regulation of actin filament bundle assembly; cellular response to mechanical stimulus; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; wound healing; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; camera-type eye development; positive regulation of apoptotic process; innate immune response; protein autophosphorylation; positive regulation of viral transcription; protein oligomerization | |
| MAP3K11 | positive regulation of JNK cascade; positive regulation of neuron apoptosis; microtubule-based process; protein autophosphorylation; protein phosphorylation; activation of MAPK activity; positive regulation of JUN kinase activity; cell proliferation; cell death; activation of JUN kinase activity; activation of JNKK activity; JNK cascade; G1 phase of mitotic cell cycle | |
| MAP3K12 | protein autophosphorylation; protein phosphorylation; intracellular protein kinase cascade; JNK cascade; histone phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation | |
| MAP3K13 | positive regulation of NF-kappaB transcription factor activity; protein autophosphorylation; JNK cascade; protein phosphorylation; activation of MAPKK activity | |
| MAP3K15 | - | |
| MAP3K19 | - | |
| MAP3K3 | protein autophosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; intracellular protein kinase cascade; activation of MAPKK activity; MAPK cascade | |
| MAP3K4 | protein phosphorylation; activation of MAPKK activity; response to stress; intracellular protein kinase cascade; JNK cascade; male germ-line sex determination; positive regulation of JUN kinase activity | |
| MAP3K5 | response to stress; JNK cascade; activation of JUN kinase activity; induction of apoptosis by extracellular signals; MAPK cascade; activation of MAPKK activity; activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to hydrogen peroxide; innate immune response; interspecies interaction between organisms; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic process; hydrogen peroxide-mediated programmed cell death; induction of apoptosis by oxidative stress | |
| MAP3K6 | MAPK cascade; activation of MAPKK activity; protein phosphorylation; signal transduction; activation of JUN kinase activity | |
| MAP3K7 | negative regulation of apoptotic process; Toll signaling pathway; innate immune response; positive regulation of JNK cascade; T cell receptor signaling pathway; response to stress; signal transduction; transforming growth factor beta receptor signaling pathway; I-kappaB kinase/NF-kappaB cascade; activation of NF-kappaB-inducing kinase activity; I-kappaB phosphorylation; JNK cascade; histone H3 acetylation; positive regulation of interleukin-2 production; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; nucleotide-binding oligomerization domain containing signaling pathway; stress-activated MAPK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of T cell activation; regulation of transcription, DNA-dependent; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; positive regu | |
| MAP3K8 | signal transduction; protein phosphorylation; cell cycle; T cell costimulation | |
| MAP3K9 | protein autophosphorylation; activation of JUN kinase activity; activation of JNKK activity; response to stress; apoptotic process; protein phosphorylation; regulation of transcription, DNA-dependent; activation of MAPK activity; MAPK cascade | |
| MAP4 | negative regulation of microtubule depolymerization | |
| MAP4K1 | activation of MAPKKK activity; protein phosphorylation; response to stress; intracellular protein kinase cascade; activation of JUN kinase activity; peptidyl-serine phosphorylation; MAPK cascade | |
| MAP4K3 | intracellular protein kinase cascade; protein phosphorylation; response to stress; JNK cascade | |
| MAP6 | - | |
| MAP6D1 | negative regulation of microtubule depolymerization; N-terminal peptidyl-L-cysteine N-palmitoylation | |
| MAP7 | protein localization in plasma membrane; establishment or maintenance of cell polarity; response to osmotic stress; microtubule cytoskeleton organization | |
| MAP7D2 | - | |
| MAP7D3 | - | |
| MAP9 | cell division; cell cycle; mitosis | |
| MAPK11 | MAPK cascade; activation of MAPK activity; stress-activated MAPK cascade; positive regulation of muscle cell differentiation; regulation of sequence-specific DNA binding transcription factor activity; nerve growth factor receptor signaling pathway; innate immune response; muscle cell differentiation; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; mRNA metabolic process; RNA metabolic process; gene expression; Ras protein signal transduction; intracellular protein kinase cascade; signal transduction; response to stress; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; Toll signaling pathway | |
| MAPK13 | cell cycle; response to osmotic stress; response to stress; regulation of transcription, DNA-dependent; MAPK cascade; intracellular protein kinase cascade; Ras protein signal transduction; peptidyl-serine phosphorylation; positive regulation of interleukin-6 production; nerve growth factor receptor signaling pathway; positive regulation of inflammatory response | |
| MAPK14 | positive regulation of muscle cell differentiation; positive regulation of reactive oxygen species metabolic process; signal transduction; platelet activation; peptidyl-serine phosphorylation; mRNA metabolic process; RNA metabolic process; gene expression; Toll signaling pathway; blood coagulation; Ras protein signal transduction; intracellular protein kinase cascade; cell surface receptor signaling pathway; cellular response to ionizing radiation; response to stress; chemotaxis; cellular component movement; apoptotic process; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; activation of MAPK activity; MAPK cascade; toll-like receptor 1 signaling pathway; stress-induced premature senescence; cellular response to growth factor stimulus; 3'-UTR-mediated mRNA stabilization; stress-activated MAPK cascade; regulation of sequence-specific DNA binding transcription factor activity; nerve growth factor receptor signali | |
| MAPK15 | MAPK cascade; protein autophosphorylation; positive regulation of protein catabolic process; response to estradiol stimulus; positive regulation of protein ubiquitination; negative regulation of DNA replication; positive regulation of protein phosphorylation | |
| MAPK3 | JAK-STAT cascade involved in growth hormone signaling pathway; interleukin-1-mediated signaling pathway; cellular response to mechanical stimulus; caveolin-mediated endocytosis; regulation of Golgi inheritance; regulation of early endosome to late endosome transport; negative regulation of apolipoprotein binding; nerve growth factor receptor signaling pathway; toll-like receptor 2 signaling pathway; fibroblast growth factor receptor signaling pathway; response to toxin; organ morphogenesis; gene expression; cytokine-mediated signaling pathway; sensory perception of pain; arachidonic acid metabolic process; platelet activation; lipopolysaccharide-mediated signaling pathway; response to lipopolysaccharide; regulation of stress-activated MAPK cascade; positive regulation of histone phosphorylation; toll-like receptor 1 signaling pathway; activation of MAPKK activity; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; positive regulation of histone acetylation; TRIF-dependent toll-lik | |
| MAPK6 | signal transduction; MAPK cascade; protein phosphorylation; cell cycle | |
| MAPK7 | ERK5 cascade; toll-like receptor 3 signaling pathway; cell cycle; signal transduction; Toll signaling pathway; peptidyl-serine phosphorylation; cell differentiation; negative regulation of heterotypic cell-cell adhesion; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; negative regulation of apoptotic process; innate immune response; regulation of angiogenesis; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; nerve growth factor receptor signaling pathway; negative regulation of inflammatory response; cellular response to transforming growth factor beta stimulus; cellular response to laminar fluid shear stress; positive regulation of protein metabolic process; stress-activated MAPK cascade; ne | |
| MAPK8IP1 | regulation of JNK cascade; negative regulation of JNK cascade; regulation of transcription, DNA-dependent; negative regulation of JUN kinase activity; vesicle-mediated transport; anti-apoptosis; JUN phosphorylation; signal transduction | |
| MAPK8IP3 | post-embryonic development; lung morphogenesis; regulation of gene expression; in utero embryonic development; forebrain development; regulation of JNK cascade; vesicle-mediated transport; lung alveolus development; activation of JUN kinase activity; axon guidance; protein localization; respiratory gaseous exchange | |
| MAPK9 | response to cadmium ion; stress-activated MAPK cascade; regulation of sequence-specific DNA binding transcription factor activity; response to stress; innate immune response; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; induction of apoptosis in response to chemical stimulus; positive regulation of macrophage derived foam cell differentiation; positive regulation of gene expression; Toll signaling pathway; JUN phosphorylation; JNK cascade; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway | |
| MAPKAPK3 | response to stress; TRIF-dependent toll-like receptor signaling pathway; signal transduction; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; activation of MAPK activity; Ras protein signal transduction; Toll signaling pathway; peptidyl-serine phosphorylation; response to lipopolysaccharide; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; macropinocytosis; innate immune response; nerve growth factor receptor signaling pathway; stress-activated MAPK cascade | |
| MAPKBP1 | - | |
| MAPRE1 | cell division; mitotic prometaphase; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; protein localization to microtubule; mitotic cell cycle; cell proliferation; negative regulation of microtubule polymerization | |
| MAPRE2 | cell cycle; signal transduction; mitosis; cell division; cell proliferation | |
| MARCH2 | endocytosis; protein ubiquitination | |
| MARCH3 | endocytosis | |
| MARCH5 | protein localization in mitochondrion; protein polyubiquitination; protein ubiquitination; protein autoubiquitination; regulation of mitochondrial fission; positive regulation of mitochondrial fission; negative regulation of cell aging | |
| MARCH6 | protein ubiquitination; protein K48-linked ubiquitination | |
| MARCH7 | - | |
| MARK1 | microtubule cytoskeleton organization; neuron migration; protein phosphorylation; cytoskeleton organization; intracellular protein kinase cascade; Wnt receptor signaling pathway | |
| MARK2 | neuron migration; regulation of axonogenesis; regulation of cytoskeleton organization; protein phosphorylation; response to oxidative stress; intracellular protein kinase cascade; multicellular organismal development; positive regulation of neuron projection development; Wnt receptor signaling pathway; establishment of cell polarity; cell differentiation; establishment or maintenance of epithelial cell apical/basal polarity; protein autophosphorylation | |
| MARK3 | - | |
| MARK4 | positive regulation of cell proliferation; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization; positive regulation of programmed cell death; microtubule bundle formation; Wnt receptor signaling pathway; protein phosphorylation; nervous system development | |
| MARS | tRNA aminoacylation for protein translation; gene expression; methionyl-tRNA aminoacylation | |
| MARVELD2 | sensory perception of sound | |
| MAS1 | response to activity; protein kinase C signaling cascade; positive regulation of inositol phosphate biosynthetic process; cellular response to peptide hormone stimulus; regulation of inflammatory response; positive regulation of DNA replication; response to drug; response to gonadotropin stimulus; hippocampus development; anatomical structure morphogenesis; male gonad development; positive regulation of cell proliferation; negative regulation of protein phosphorylation; G-protein coupled receptor signaling pathway; cell proliferation; spermatogenesis; activation of NF-kappaB-inducing kinase activity | |
| MASP2 | proteolysis; complement activation, lectin pathway; complement activation; complement activation, classical pathway; innate immune response | |
| MAST1 | intracellular protein kinase cascade; cytoskeleton organization; protein phosphorylation | |
| MAST2 | regulation of interleukin-12 biosynthetic process; spermatid differentiation; protein phosphorylation | |
| MASTL | response to DNA damage stimulus; regulation of cell cycle; mitosis; cell division; G2/M transition of mitotic cell cycle; negative regulation of protein phosphatase type 2A activity; phosphorylation | |
| MAT2A | circadian rhythm; xenobiotic metabolic process; response to light stimulus; response to hormone stimulus; methylation; cellular nitrogen compound metabolic process; response to drug; small molecule metabolic process; response to cAMP; S-adenosylmethionine biosynthetic process; sulfur amino acid metabolic process | |
| MATK | cell proliferation; positive regulation of cell proliferation; mesoderm development; protein phosphorylation | |
| MATN1 | protein complex assembly | |
| MATN4 | - | |
| MATR3 | - | |
| MAU2 | mitosis; cell division; cell cycle; chromosome segregation; maintenance of mitotic sister chromatid cohesion | |
| MAVS | signal transduction; negative regulation of type I interferon production; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor import into nucleus; defense response to bacterium; positive regulation of protein import into nucleus, translocation; positive regulation of tumor necrosis factor production; positive regulation of interleukin-8 production; positive regulation of interferon-beta production; positive regulation of interferon-alpha production; interspecies interaction between organisms; innate immune response; positive regulation of transcription from RNA polymerase II promoter; response to virus; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of defense response to virus by host; activation of innate immune response; positive regulation of protein phosphorylation; positive regulation of type I interferon-mediated signaling pathway; cellular response to exogenous dsRNA; positive regulation of chemo | |
| MAX | cellular response to peptide hormone stimulus; retina development in camera-type eye; neuron apoptosis; response to axon injury; response to insulin stimulus; response to organic nitrogen; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; protein complex assembly; negative regulation of gene expression; cellular response to starvation | |
| MAZ | regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter; termination of RNA polymerase II transcription | |
| MB21D1 | response to virus | |
| MBD1 | negative regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| MBD2 | positive regulation of Wnt receptor signaling pathway; regulation of cell proliferation; maternal behavior; cellular protein complex assembly; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| MBD5 | - | |
| MBD6 | - | |
| MBLAC1 | - | |
| MBNL1 | regulation of alternative nuclear mRNA splicing, via spliceosome; myoblast differentiation; regulation of RNA splicing; embryonic limb morphogenesis; RNA splicing; skeletal muscle tissue development; nervous system development; mRNA processing; mRNA splice site selection; in utero embryonic development | |
| MBNL2 | mRNA processing; regulation of RNA splicing | |
| MBNL3 | negative regulation of myoblast differentiation; mRNA processing; multicellular organismal development; regulation of RNA splicing | |
| MBOAT7 | phospholipid biosynthetic process | |
| MBP | immune response; synaptic transmission; central nervous system development; axon ensheathment | |
| MBTPS1 | lipid metabolic process; regulation of transcription factor import into nucleus; endoplasmic reticulum unfolded protein response; cholesterol metabolic process; steroid metabolic process; metabolic process; activation of signaling protein activity involved in unfolded protein response; proteolysis | |
| MC2R | G-protein coupled receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of cAMP biosynthetic process | |
| MC3R | positive regulation of cAMP biosynthetic process; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger | |
| MC4R | diet induced thermogenesis; energy reserve metabolic process; G-protein signaling, coupled to cAMP nucleotide second messenger; feeding behavior; regulation of metabolic process; insulin secretion; positive regulation of cAMP biosynthetic process; response to insulin stimulus; positive regulation of bone resorption | |
| MCAM | glomerular filtration; anatomical structure morphogenesis; vascular wound healing; cell adhesion | |
| MCAT | fatty acid biosynthetic process; metabolic process | |
| MCC | signal transduction; negative regulation of epithelial cell migration; Wnt receptor signaling pathway; negative regulation of epithelial cell proliferation; negative regulation of canonical Wnt receptor signaling pathway | |
| MCCC1 | cellular nitrogen compound metabolic process; leucine catabolic process; small molecule metabolic process; branched chain family amino acid catabolic process; biotin metabolic process | |
| MCCC2 | leucine catabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; coenzyme A metabolic process; branched chain family amino acid catabolic process | |
| MCF2 | regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; intracellular signal transduction; induction of apoptosis by extracellular signals; small GTPase mediated signal transduction; apoptotic process | |
| MCF2L2 | regulation of Rho protein signal transduction | |
| MCFD2 | protein N-linked glycosylation via asparagine; vesicle-mediated transport; carboxylic acid metabolic process; post-translational protein modification; cellular protein metabolic process; protein transport | |
| MCHR1 | elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; G-protein coupled receptor signaling pathway; generation of precursor metabolites and energy; feeding behavior; positive regulation of calcium ion transport | |
| MCM2 | G1/S transition of mitotic cell cycle; cell cycle; DNA strand elongation involved in DNA replication; cell cycle checkpoint; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; DNA-dependent DNA replication initiation; DNA unwinding involved in replication; mitotic cell cycle; DNA replication; nucleosome assembly | |
| MCM3 | DNA replication; DNA strand elongation involved in DNA replication; DNA-dependent DNA replication initiation; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint | |
| MCM3AP | DNA replication; protein import into nucleus | |
| MCM4 | DNA strand elongation involved in DNA replication; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; DNA-dependent DNA replication initiation; cell cycle checkpoint | |
| MCM5 | M/G1 transition of mitotic cell cycle; DNA strand elongation involved in DNA replication; DNA-dependent DNA replication initiation; DNA replication; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint | |
| MCM7 | cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; DNA-dependent DNA replication initiation; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA unwinding involved in replication; DNA strand elongation involved in DNA replication; response to DNA damage stimulus; cell proliferation; regulation of phosphorylation; DNA replication | |
| MCM8 | S phase of mitotic cell cycle; regulation of transcription, DNA-dependent; DNA strand elongation involved in DNA replication; DNA replication; mitotic cell cycle; cell cycle checkpoint; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle | |
| MCM9 | DNA replication | |
| MCMDC2 | DNA replication | |
| MCOLN2 | ion transport | |
| MCOLN3 | sensory perception of sound; auditory receptor cell differentiation; locomotory behavior; ion transport | |
| MCPH1 | - | |
| MCRS1 | DNA repair; histone H4-K8 acetylation; histone H4-K5 acetylation; histone H4-K16 acetylation; regulation of transcription, DNA-dependent; DNA recombination; protein modification process | |
| MCTP1 | calcium-mediated signaling | |
| MCTP2 | calcium-mediated signaling | |
| MCU | protein complex oligomerization; elevation of mitochondrial calcium ion concentration; calcium ion transmembrane transport; ion transport; mitochondrial calcium ion transport; calcium-mediated signaling | |
| MDFI | cytoplasmic sequestering of transcription factor; trophoblast giant cell differentiation; embryonic skeletal system morphogenesis; negative regulation of DNA binding; negative regulation of Wnt receptor signaling pathway; cell differentiation; dorsal/ventral axis specification; embryo development; activation of JUN kinase activity; negative regulation of transcription from RNA polymerase II promoter | |
| MDFIC | positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of viral transcription; interspecies interaction between organisms; regulation of Wnt receptor signaling pathway; activation of JUN kinase activity; negative regulation of protein import into nucleus | |
| MDGA2 | spinal cord motor neuron differentiation | |
| MDH1B | malate metabolic process; tricarboxylic acid cycle; carbohydrate metabolic process | |
| MDM1 | retina development in camera-type eye | |
| MDM4 | negative regulation of cell cycle arrest; negative regulation of transcription from RNA polymerase II promoter; protein complex assembly; apoptotic process; cell proliferation; positive regulation of cell proliferation; negative regulation of cell proliferation; negative regulation of protein catabolic process; negative regulation of apoptotic process; G0 to G1 transition; protein stabilization; cellular response to hypoxia | |
| MDN1 | ATP catabolic process; protein complex assembly | |
| ME3 | oxidation-reduction process; aerobic respiration; oxygen metabolic process; malate metabolic process; pyruvate metabolic process | |
| MEAF6 | histone H4-K8 acetylation; histone H4-K12 acetylation; histone H4-K5 acetylation; histone H4-K16 acetylation; histone H3-K14 acetylation; histone H2A acetylation; chromatin modification; regulation of transcription, DNA-dependent | |
| MECOM | negative regulation of JNK cascade; forebrain development; regulation of cell cycle; pericardium development; hemopoietic stem cell proliferation; embryonic forelimb morphogenesis; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of programmed cell death; regulation of cell proliferation; embryonic hindlimb morphogenesis; negative regulation of transforming growth factor beta receptor signaling pathway; cell differentiation; post-embryonic development; response to bacterium; response to external stimulus; inflammatory response; neutrophil homeostasis; regulation of transcription, DNA-dependent; apoptotic process | |
| MECP2 | negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| MED1 | ventricular trabecula myocardium morphogenesis; liver development; embryonic placenta development; lens development in camera-type eye; thyroid hormone mediated signaling pathway; positive regulation of mammary gland epithelial cell proliferation; androgen receptor signaling pathway; intracellular steroid hormone receptor signaling pathway; monocyte differentiation; keratinocyte differentiation; negative regulation of keratinocyte proliferation; positive regulation of gene expression; gene expression; lactation; brain development; cellular response to epidermal growth factor stimulus; transcription initiation from RNA polymerase II promoter; thyroid hormone generation; androgen biosynthetic process; multicellular organismal development; regulation of RNA biosynthetic process; positive regulation of hepatocyte proliferation; positive regulation of receptor activity; cellular response to thyroid hormone stimulus; cellular response to steroid hormone stimulus; regulation of transcription from RNA polymerase I pr | |
| MED12 | intracellular steroid hormone receptor signaling pathway; gene expression; negative regulation of Wnt receptor signaling pathway; androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter | |
| MED12L | regulation of transcription from RNA polymerase II promoter | |
| MED13 | positive regulation of transcription, DNA-dependent; gene expression; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription initiation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter | |
| MED13L | regulation of transcription from RNA polymerase II promoter | |
| MED14 | transcription initiation from RNA polymerase II promoter; gene expression; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter | |
| MED16 | regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent | |
| MED17 | positive regulation of transcription from RNA polymerase II promoter; androgen receptor signaling pathway; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; gene expression; positive regulation of transcription, DNA-dependent; intracellular steroid hormone receptor signaling pathway | |
| MED18 | regulation of transcription from RNA polymerase II promoter | |
| MED20 | transcription from RNA polymerase II promoter; transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; gene expression | |
| MED21 | positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; blastocyst development | |
| MED22 | regulation of transcription from RNA polymerase II promoter | |
| MED23 | gene expression; transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| MED24 | protein heterooligomerization; regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; gene expression; androgen receptor signaling pathway; intracellular steroid hormone receptor signaling pathway | |
| MED25 | regulation of transcription, DNA-dependent; gene expression; positive regulation of chromatin binding; positive regulation of transcription from RNA polymerase II promoter; negative regulation of fibroblast proliferation; positive regulation of cell cycle arrest; positive regulation of mediator complex assembly; negative regulation of transcription from RNA polymerase II promoter | |
| MED27 | gene expression; transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter | |
| MED28 | regulation of transcription, DNA-dependent | |
| MEFV | inflammatory response; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; innate immune response | |
| MEGF10 | phagocytosis; cell adhesion | |
| MEGF6 | - | |
| MEIOB | - | |
| MEIS2 | transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| MEIS3 | - | |
| MELK | hemopoiesis; G2/M transition of mitotic cell cycle; apoptotic process; cell cycle; cell proliferation; positive regulation of apoptotic process; protein autophosphorylation; neural precursor cell proliferation | |
| MEN1 | negative regulation of osteoblast differentiation; embryo development; negative regulation of sequence-specific DNA binding transcription factor activity; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic process; histone lysine methylation; positive regulation of protein binding; positive regulation of histone methylation; positive regulation of transforming growth factor beta receptor signaling pathway; hemopoiesis; response to gamma radiation; regulation of activin receptor signaling pathway; positive regulation of osteoblast differentiation; negative regulation of cyclin-dependent protein kinase activity; negative regulation of cell cycle; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of JNK cascade; negative regulation of organ growth; embryonic skeletal system morphogenesis; positive regulation of cell division; negative regulation of | |
| MEOX1 | positive regulation of transcription from RNA polymerase II promoter; multicellular organismal development; somite specification | |
| MEOX2 | limb development; palate development; blood circulation; skeletal muscle tissue development; multicellular organismal development; somite specification; angiogenesis | |
| MEPCE | - | |
| MEPE | skeletal system development | |
| MERTK | platelet activation; substrate adhesion-dependent cell spreading; apoptotic cell clearance; retina development in camera-type eye; vagina development; secretion by cell; negative regulation of lymphocyte activation; cell surface receptor signaling pathway; leukocyte migration; blood coagulation; spermatogenesis; protein kinase B signaling cascade; natural killer cell differentiation; protein phosphorylation; phagocytosis; cell-cell signaling | |
| MESDC1 | - | |
| MESDC2 | protein localization at cell surface; Wnt receptor signaling pathway; mesoderm development; protein folding | |
| MESP2 | signal transduction involved in regulation of gene expression; mesodermal cell migration; Notch signaling pathway; somitogenesis; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter | |
| MEST | mesoderm development; response to retinoic acid; regulation of lipid storage | |
| MET | axon guidance; branching morphogenesis of a tube; hepatocyte growth factor receptor signaling pathway; cell proliferation; signal transduction; cell surface receptor signaling pathway; multicellular organismal development | |
| METAP2 | cellular process; N-terminal protein amino acid modification; proteolysis; peptidyl-methionine modification; protein processing | |
| METRN | positive regulation of axonogenesis; multicellular organismal development; nervous system development; glial cell differentiation | |
| METTL12 | - | |
| METTL13 | metabolic process | |
| METTL14 | RNA methylation; nucleobase-containing compound metabolic process | |
| METTL16 | - | |
| METTL20 | - | |
| METTL21A | - | |
| METTL21C | - | |
| METTL3 | nucleobase-containing compound metabolic process; gene expression; RNA methylation | |
| METTL5 | - | |
| MFAP3 | - | |
| MFAP3L | - | |
| MFF | - | |
| MFGE8 | phagocytosis, engulfment; angiogenesis; phagocytosis, recognition; cell adhesion; single fertilization; positive regulation of cell proliferation; response to estrogen stimulus; interspecies interaction between organisms; positive regulation of apoptotic cell clearance | |
| MFHAS1 | - | |
| MFI2 | ion transport; iron ion transport; cellular iron ion homeostasis | |
| MFN1 | mitochondrial fusion; GTP catabolic process | |
| MFNG | pattern specification process | |
| MFSD11 | - | |
| MFSD12 | transport | |
| MFSD14A | transmembrane transport | |
| MFSD14B | transmembrane transport | |
| MFSD5 | transport | |
| MFSD6 | transmembrane transport | |
| MFSD7 | transmembrane transport | |
| MFSD8 | cell death; transmembrane transport | |
| MFSD9 | transmembrane transport | |
| MGARP | - | |
| MGAT1 | cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; protein glycosylation; carbohydrate metabolic process | |
| MGAT2 | protein N-linked glycosylation; oligosaccharide metabolic process; oligosaccharide biosynthetic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process | |
| MGAT3 | protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process | |
| MGAT4B | protein N-linked glycosylation via asparagine; N-glycan processing; carbohydrate metabolic process; post-translational protein modification; cellular protein metabolic process | |
| MGAT4C | cellular protein metabolic process; post-translational protein modification; carbohydrate metabolic process; protein N-linked glycosylation via asparagine | |
| MGAT5 | protein N-linked glycosylation; metabolic process; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine | |
| MGAT5B | - | |
| MGEA5 | positive regulation of glucose import; N-acetylglucosamine metabolic process; glycoprotein catabolic process; protein targeting to membrane; aging; positive regulation of calcium ion transport into cytosol; negative regulation of cardiac muscle adaptation; positive regulation of cell killing; positive regulation of insulin secretion; positive regulation of protein complex disassembly; positive regulation of proteolysis; dATP metabolic process; response to steroid hormone stimulus; positive regulation of DNA metabolic process; positive regulation of mitochondrial depolarization; negative regulation of protein glycosylation; positive regulation of growth hormone secretion; necrotic cell death | |
| MGME1 | - | |
| MGMT | response to drug; cellular response to ionizing radiation; cellular response to organic cyclic compound; mammary gland epithelial cell differentiation; negative regulation of cell death; response to folic acid; positive regulation of DNA repair; response to ethanol; DNA repair; DNA methylation; DNA dealkylation involved in DNA repair; response to toxin; methylation; cellular response to oxidative stress; regulation of cysteine-type endopeptidase activity involved in apoptotic process; DNA ligation | |
| MGST1 | glutathione metabolic process; xenobiotic metabolic process; response to organic nitrogen; response to lipopolysaccharide; Leydig cell differentiation; response to drug; protein homotrimerization; small molecule metabolic process | |
| MGST2 | small molecule metabolic process; response to lipopolysaccharide; leukotriene biosynthetic process; response to organic nitrogen; xenobiotic metabolic process; glutathione biosynthetic process; leukotriene production involved in inflammatory response | |
| MIA3 | negative regulation of cell adhesion; protein transport; negative regulation of cell migration; wound healing; exocytosis; positive regulation of leukocyte migration | |
| MIB1 | heart development; positive regulation of endocytosis; negative regulation of neuron differentiation; Notch signaling pathway; heart looping; neural tube formation; somitogenesis; in utero embryonic development; blood vessel development | |
| MIB2 | Notch signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction | |
| MICAL2 | - | |
| MICALL1 | - | |
| MICALL2 | endocytosis | |
| MICU2 | - | |
| MICU3 | - | |
| MID2 | - | |
| MIDN | - | |
| MIEF1 | mitochondrial fusion | |
| MIEN1 | negative regulation of apoptotic process; positive regulation of cell migration; positive regulation of filopodium assembly; cell redox homeostasis | |
| MIER1 | regulation of transcription, DNA-dependent; signal transduction; positive regulation of chromatin silencing; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| MIER2 | regulation of transcription, DNA-dependent | |
| MIER3 | regulation of transcription, DNA-dependent | |
| MIOS | - | |
| MIP | water transport; lens development in camera-type eye; transmembrane transport; response to stimulus; canalicular bile acid transport; visual perception | |
| MIPEP | proteolysis; protein processing involved in protein targeting to mitochondrion | |
| MIPOL1 | - | |
| MIS18BP1 | mitosis; cell division; CenH3-containing nucleosome assembly at centromere; cell cycle; nucleosome assembly | |
| MITD1 | protein transport | |
| MITF | positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; melanocyte differentiation; multicellular organismal development; protein complex assembly; regulation of transcription, DNA-dependent | |
| MKI67 | organ regeneration; cell proliferation; meiosis; cell cycle; DNA metabolic process; cellular response to heat | |
| MKL1 | smooth muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; anti-apoptosis | |
| MKL2 | regulation of transcription, DNA-dependent; multicellular organismal development; muscle organ development; cell differentiation; positive regulation of striated muscle tissue development; positive regulation of transcription from RNA polymerase II promoter | |
| MKLN1 | signal transduction | |
| MKNK1 | regulation of translation; protein phosphorylation; intracellular protein kinase cascade; fibroblast growth factor receptor signaling pathway; peptidyl-serine phosphorylation | |
| MKNK2 | regulation of translation; protein phosphorylation; apoptotic process; cell surface receptor signaling pathway; intracellular protein kinase cascade; hemopoiesis; cellular response to arsenic-containing substance | |
| MKRN2 | - | |
| MKRN3 | - | |
| MKS1 | cell projection organization; cilium assembly; cilium morphogenesis; branching morphogenesis of a tube | |
| MKX | muscle organ development; multicellular organismal development | |
| MLF2 | defense response | |
| MLH1 | reciprocal meiotic recombination; spindle midzone assembly involved in meiosis; cellular response to organic cyclic compound; pachytene; nuclear-transcribed mRNA poly(A) tail shortening; resolution of meiotic recombination intermediates; response to hypoxia; ATP catabolic process; mismatch repair; double-strand break repair via nonhomologous end joining; cell cycle; male meiosis chromosome segregation; spermatogenesis; DNA damage response, signal transduction resulting in induction of apoptosis; oogenesis; negative regulation of mitotic recombination; isotype switching; meiotic metaphase I plate congression; response to drug; somatic hypermutation of immunoglobulin genes; response to toxin | |
| MLIP | - | |
| MLKL | - | |
| MLLT1 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; negative regulation of protein kinase activity | |
| MLLT10 | positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| MLLT3 | regulation of transcription, DNA-dependent; segment specification; anterior/posterior pattern specification | |
| MLLT4 | adherens junction organization; cell-cell junction organization; cell adhesion; signal transduction; cell-cell signaling; cell junction assembly | |
| MLX | small molecule metabolic process; negative regulation of transcription, DNA-dependent; energy reserve metabolic process; regulation of transcription, DNA-dependent; nucleocytoplasmic transport; positive regulation of cellular metabolic process | |
| MMAA | - | |
| MMD | cytolysis | |
| MME | replicative senescence; cellular response to UV-B; cellular response to UV-A; cellular response to cytokine stimulus; beta-amyloid metabolic process; sensory perception of pain; peptide metabolic process; proteolysis; kidney development; creatinine metabolic process | |
| MMEL1 | proteolysis | |
| MMP1 | proteolysis; blood coagulation; metabolic process; collagen catabolic process; interspecies interaction between organisms; leukocyte migration | |
| MMP14 | lung development; cell migration; response to organic cyclic compound; response to hormone stimulus; response to mechanical stimulus; metabolic process; response to oxidative stress; proteolysis; endothelial cell proliferation; response to hypoxia; ovarian follicle development; angiogenesis; ossification; astrocyte cell migration; response to estrogen stimulus; branching morphogenesis of a tube; tissue remodeling; zymogen activation; negative regulation of focal adhesion assembly | |
| MMP15 | positive regulation of catalytic activity; response to estradiol stimulus; metabolic process; proteolysis; protein modification process | |
| MMP16 | proteolysis; metabolic process; collagen catabolic process; positive regulation of catalytic activity | |
| MMP19 | ovarian follicle development; response to cAMP; collagen catabolic process; cell differentiation; response to hormone stimulus; metabolic process; multicellular organismal development; proteolysis; luteolysis; ovulation from ovarian follicle; angiogenesis | |
| MMP2 | angiogenesis; response to hypoxia; cellular response to amino acid stimulus; bone trabecula formation; face morphogenesis; blood vessel maturation; collagen catabolic process; metabolic process; intramembranous ossification; proteolysis | |
| MMP20 | regulation of enamel mineralization; metabolic process; proteolysis | |
| MMP25 | metabolic process; proteolysis; inflammatory response | |
| MMP26 | collagen catabolic process; proteolysis | |
| MMP27 | metabolic process; collagen catabolic process; proteolysis | |
| MMP3 | cellular response to cell-matrix adhesion; female pregnancy; cellular response to amino acid stimulus; response to interleukin-1; wound healing; response to tumor necrosis factor; response to lipopolysaccharide; response to estradiol stimulus; collagen catabolic process; metabolic process; response to hypoxia; proteolysis | |
| MMP9 | collagen catabolic process; extracellular matrix organization; positive regulation of synaptic plasticity; response to estradiol stimulus; response to lipopolysaccharide; response to retinoic acid; response to tumor necrosis factor; response to nicotine; response to drug; positive regulation of apoptotic process; response to ethanol; positive regulation of angiogenesis; tissue remodeling; positive regulation of keratinocyte migration; response to hyperoxia; anatomical structure regression; cellular response to interleukin-1; cellular response to low-density lipoprotein particle stimulus; cellular response to cell-matrix adhesion; proteolysis; response to mechanical stimulus; response to heat; response to radiation; metabolic process; response to nutrient; response to oxidative stress; macrophage differentiation; response to hypoxia; ossification; skeletal system development; cell growth; transformation of host cell by virus | |
| MMRN1 | platelet activation; blood coagulation; cell adhesion; platelet degranulation | |
| MMS22L | replication fork processing; DNA repair; double-strand break repair via homologous recombination | |
| MN1 | intramembranous ossification | |
| MNDA | response to DNA damage stimulus; negative regulation of B cell proliferation; positive regulation of apoptotic process; B cell receptor signaling pathway; regulation of transcription, DNA-dependent; cellular defense response | |
| MNS1 | meiosis | |
| MNT | multicellular organismal development; regulation of cell cycle; regulation of apoptotic process; negative regulation of cell proliferation; cell aging; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| MNX1 | regulation of transcription from RNA polymerase II promoter; humoral immune response; regulation of transcription, DNA-dependent; neuron migration; motor axon guidance; post-embryonic development; anatomical structure morphogenesis; diaphragm development; neuron projection morphogenesis; cell morphogenesis involved in neuron differentiation; endocrine pancreas development; central nervous system neuron differentiation; dorsal/ventral neural tube patterning; nerve development; spinal cord motor neuron cell fate specification | |
| MOB1B | hippo signaling cascade; positive regulation of phosphorylation; protein autophosphorylation | |
| MOB3A | - | |
| MOB4 | transport | |
| MOCOS | water-soluble vitamin metabolic process; small molecule metabolic process; vitamin metabolic process; Mo-molybdopterin cofactor biosynthetic process; molybdopterin cofactor biosynthetic process; molybdopterin cofactor metabolic process | |
| MOCS1 | vitamin metabolic process; small molecule metabolic process; molybdopterin cofactor biosynthetic process; Mo-molybdopterin cofactor biosynthetic process; water-soluble vitamin metabolic process | |
| MOCS2 | vitamin metabolic process; water-soluble vitamin metabolic process; Mo-molybdopterin cofactor biosynthetic process; molybdopterin cofactor biosynthetic process; small molecule metabolic process | |
| MOGAT3 | glycerol metabolic process; lipid biosynthetic process | |
| MOGS | protein N-linked glycosylation via asparagine; oligosaccharide metabolic process; protein N-linked glycosylation; protein folding; post-translational protein modification; cellular protein metabolic process | |
| MON1A | - | |
| MON1B | - | |
| MON2 | protein transport; Golgi to endosome transport | |
| MORC1 | cell differentiation; multicellular organismal development; spermatogenesis | |
| MORN1 | - | |
| MOS | - | |
| MOV10 | gene silencing by RNA; regulation of transcription, DNA-dependent; mRNA cleavage involved in gene silencing by miRNA | |
| MOV10L1 | multicellular organismal development; germ cell development; spermatogenesis | |
| MOXD1 | catecholamine metabolic process | |
| MPDU1 | oligosaccharide biosynthetic process; transport; dolichol-linked oligosaccharide biosynthetic process; protein folding | |
| MPEG1 | - | |
| MPHOSPH10 | RNA splicing, via transesterification reactions; rRNA processing; RNA processing; RNA splicing; negative regulation of phosphatase activity | |
| MPHOSPH8 | regulation of DNA methylation; negative regulation of transcription, DNA-dependent; cell cycle | |
| MPHOSPH9 | M phase of mitotic cell cycle | |
| MPI | dolichol-linked oligosaccharide biosynthetic process; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; GDP-mannose biosynthetic process; metabolic process; carbohydrate metabolic process | |
| MPP3 | signal transduction | |
| MPP5 | cell junction assembly; myelin assembly; protein localization to myelin sheath abaxonal region; peripheral nervous system myelin maintenance; cell-cell junction organization; establishment of protein localization in plasma membrane; tight junction assembly | |
| MPP6 | protein complex assembly | |
| MPPED2 | nervous system development | |
| MPST | cyanate catabolic process; response to toxin | |
| MPZ | synaptic transmission | |
| MPZL1 | cell-cell signaling; transmembrane receptor protein tyrosine kinase signaling pathway | |
| MPZL3 | cell adhesion | |
| MR1 | antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation; immune response | |
| MRAP2 | positive regulation of cAMP biosynthetic process; protein localization at cell surface | |
| MRAS | GTP catabolic process; actin cytoskeleton organization; muscle organ development; multicellular organismal development; Ras protein signal transduction; signal transduction | |
| MRC2 | endocytosis | |
| MRE11A | regulation of mitotic recombination; nucleic acid phosphodiester bond hydrolysis; positive regulation of kinase activity; negative regulation of DNA endoreduplication; DNA duplex unwinding; positive regulation of protein autophosphorylation; cell proliferation; heart development; reciprocal meiotic recombination; meiosis; cell cycle checkpoint; double-strand break repair via homologous recombination; DNA repair; double-strand break repair; double-strand break repair via nonhomologous end joining; DNA recombination; telomere maintenance via telomerase; sister chromatid cohesion; synapsis | |
| MRGPRD | - | |
| MROH7 | - | |
| MROH9 | - | |
| MRPL17 | translation | |
| MRPL2 | translation | |
| MRPL20 | translation | |
| MRPL30 | translation | |
| MRPL34 | translation | |
| MRPL37 | translation | |
| MRPL39 | - | |
| MRPL4 | translation | |
| MRPL46 | - | |
| MRPL47 | translation | |
| MRPL50 | - | |
| MRPL53 | - | |
| MRPL9 | translation | |
| MRPS11 | translation; DNA damage response, detection of DNA damage | |
| MRPS12 | translation | |
| MRPS25 | translation | |
| MRPS30 | apoptotic process; translation | |
| MRPS34 | - | |
| MRPS35 | peptide biosynthetic process; DNA damage response, detection of DNA damage | |
| MRPS9 | DNA damage response, detection of DNA damage; peptide biosynthetic process; translation | |
| MRRF | ribosome disassembly; translation | |
| MRS2 | ion transport | |
| MS4A1 | immune response; B cell activation | |
| MS4A10 | - | |
| MS4A14 | - | |
| MS4A15 | - | |
| MS4A3 | - | |
| MS4A4A | - | |
| MS4A5 | - | |
| MS4A8 | - | |
| MSANTD1 | - | |
| MSANTD4 | - | |
| MSH2 | somatic hypermutation of immunoglobulin genes; positive regulation of helicase activity; negative regulation of DNA recombination; isotype switching; negative regulation of reciprocal meiotic recombination; maintenance of DNA repeat elements; negative regulation of neuron apoptosis; response to amino acid stimulus; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; response to drug; intra-S DNA damage checkpoint; B cell differentiation; B cell mediated immunity; somatic recombination of immunoglobulin gene segments; ATP catabolic process; DNA repair; postreplication repair; response to organic cyclic compound; meiotic mismatch repair; in utero embryonic development; oxidative phosphorylation; response to UV-B; response to X-ray; male gonad development; determination of adult lifespan; spermatogenesis; germ cell development; cell cycle arrest; meiotic gene conversion; double-strand break repair; mismatch repair | |
| MSH3 | negative regulation of DNA recombination; meiotic mismatch repair; DNA repair; mismatch repair; reciprocal meiotic recombination; somatic recombination of immunoglobulin gene segments; maintenance of DNA repeat elements; positive regulation of helicase activity | |
| MSH6 | meiotic mismatch repair; positive regulation of helicase activity; determination of adult lifespan; induction of apoptosis by intracellular signals; DNA damage response, signal transduction resulting in induction of apoptosis; response to UV; reciprocal meiotic recombination; mismatch repair; DNA repair; ATP catabolic process; somatic hypermutation of immunoglobulin genes; somatic recombination of immunoglobulin gene segments; maintenance of DNA repeat elements; isotype switching; negative regulation of DNA recombination | |
| MSI2 | stem cell development | |
| MSLN | cell adhesion | |
| MSMB | - | |
| MSMO1 | fatty acid biosynthetic process; cholesterol biosynthetic process; steroid metabolic process; small molecule metabolic process; fatty acid metabolic process | |
| MSMP | - | |
| MSR1 | receptor-mediated endocytosis; positive regulation of cholesterol storage; positive regulation of macrophage derived foam cell differentiation; lipoprotein transport; response to chemical stimulus; cholesterol transport; plasma lipoprotein particle clearance | |
| MSRA | protein modification process; methionine metabolic process; response to oxidative stress; aging; protein metabolic process | |
| MSRB2 | regulation of transcription, DNA-dependent; protein repair | |
| MSRB3 | protein repair | |
| MST1R | positive regulation of cell proliferation; single fertilization; positive regulation of protein kinase B signaling cascade; cellular component movement; defense response; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; multicellular organismal development; innate immune response; positive regulation of MAP kinase activity; response to virus | |
| MSTN | negative regulation of muscle hypertrophy; transforming growth factor beta receptor signaling pathway; muscle organ development; response to heat; response to gravity; skeletal muscle atrophy; response to estrogen stimulus; response to muscle activity; ovulation cycle process; response to testosterone stimulus; growth; skeletal muscle tissue regeneration; response to electrical stimulus; response to glucocorticoid stimulus; negative regulation of skeletal muscle tissue growth; positive regulation of transcription, DNA-dependent; response to ethanol | |
| MSX1 | positive regulation of BMP signaling pathway; middle ear morphogenesis; odontogenesis of dentin-containing tooth; regulation of odontogenesis; embryonic nail plate morphogenesis; positive regulation of apoptotic process; negative regulation of apoptotic process; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation; protein stabilization; negative regulation of striated muscle cell differentiation; palate development; face morphogenesis; bone morphogenesis; cartilage morphogenesis; mammary gland epithelium development; BMP signaling pathway involved in heart development; negative regulation of transcription regulatory region DNA binding; embryonic forelimb morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell morphogenesis; in utero embryonic development; epithelial to mesenchymal transition; heart morphogenesis; epithelial to mesenchymal transiti | |
| MT1H | cellular zinc ion homeostasis; nitric oxide mediated signal transduction; detoxification of copper ion; negative regulation of growth; cellular response to cadmium ion; cellular response to zinc ion | |
| MT4 | cellular metal ion homeostasis | |
| MTA1 | signal transduction | |
| MTA2 | positive regulation of transcription from RNA polymerase II promoter; chromatin assembly or disassembly; negative regulation of transcription from RNA polymerase II promoter | |
| MTBP | cell cycle; cell cycle arrest; traversing start control point of mitotic cell cycle; negative regulation of cell proliferation | |
| MTCH2 | transport | |
| MTCL1 | - | |
| MTCP1 | cell proliferation | |
| MTDH | positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein kinase B signaling cascade; positive regulation of NF-kappaB transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of autophagy; lipopolysaccharide-mediated signaling pathway; tight junction assembly; negative regulation of apoptotic process; positive regulation of angiogenesis | |
| MTERF4 | - | |
| MTF1 | regulation of transcription from RNA polymerase II promoter; response to oxidative stress; response to metal ion; positive regulation of transcription from RNA polymerase II promoter; response to cadmium ion | |
| MTF2 | - | |
| MTFP1 | mitochondrial fission; apoptotic process | |
| MTFR2 | - | |
| MTG2 | - | |
| MTHFD1 | purine nucleotide biosynthetic process; folic acid metabolic process; folic acid-containing compound biosynthetic process; methionine biosynthetic process; cellular amino acid biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process; one-carbon metabolic process; histidine biosynthetic process; small molecule metabolic process | |
| MTHFD1L | one-carbon metabolic process; folic acid-containing compound metabolic process; folic acid-containing compound biosynthetic process; formate metabolic process; tetrahydrofolate metabolic process; oxidation-reduction process | |
| MTHFD2L | oxidation-reduction process; histidine biosynthetic process; cellular amino acid biosynthetic process; one-carbon metabolic process; purine nucleotide biosynthetic process; methionine biosynthetic process; folic acid-containing compound biosynthetic process | |
| MTHFR | water-soluble vitamin metabolic process; cellular amino acid metabolic process; homocysteine metabolic process; folic acid metabolic process; small molecule metabolic process; methionine biosynthetic process; blood circulation; vitamin metabolic process | |
| MTIF2 | translation; regulation of translational initiation | |
| MTIF3 | regulation of translational initiation; translation; ribosome disassembly | |
| MTM1 | endosome to lysosome transport; protein dephosphorylation; mitochondrion morphogenesis; mitochondrion distribution; phosphatidylinositol dephosphorylation; intermediate filament organization; regulation of vacuole organization; protein transport | |
| MTMR1 | - | |
| MTMR11 | - | |
| MTMR12 | - | |
| MTMR14 | - | |
| MTMR2 | negative regulation of receptor catabolic process; protein dephosphorylation; negative regulation of endocytosis; protein tetramerization; negative regulation of excitatory postsynaptic membrane potential; dendritic spine maintenance; negative regulation of receptor internalization; positive regulation of early endosome to late endosome transport | |
| MTMR3 | peptidyl-tyrosine dephosphorylation; protein dephosphorylation; phosphatidylinositol dephosphorylation | |
| MTMR4 | protein dephosphorylation; peptidyl-tyrosine dephosphorylation | |
| MTMR8 | - | |
| MTMR9 | - | |
| MTNR1A | G-protein signaling, coupled to cyclic nucleotide second messenger; mating behavior; circadian rhythm | |
| MTO1 | oxidation-reduction process; tRNA processing | |
| MTOR | cellular response to hypoxia; negative regulation of cell size; cellular response to nutrient levels; TOR signaling cascade; regulation of fatty acid beta-oxidation; regulation of response to food; regulation of Rac GTPase activity; response to insulin stimulus; regulation of actin cytoskeleton organization; growth; response to amino acid stimulus; regulation of carbohydrate utilization; positive regulation of translation; positive regulation of endothelial cell proliferation; regulation of protein kinase activity; positive regulation of transcription from RNA polymerase III promoter; protein autophosphorylation; positive regulation of lipid biosynthetic process; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of stress fiber assembly; negative regulation of NFAT protein import into nucleus; positive regulation of protein kinase B signaling cascade; T cell costimulation; positive regulation o | |
| MTPAP | histone mRNA catabolic process; cell death; mRNA processing; mRNA polyadenylation; transcription, DNA-dependent | |
| MTRF1 | regulation of translational termination | |
| MTRR | cellular amino acid biosynthetic process; oxidation-reduction process; methionine biosynthetic process; methionine metabolic process | |
| MTSS1 | epithelial cell proliferation involve in renal tubule morphogenesis; cellular component movement; nephron tubule epithelial cell differentiation; glomerulus morphogenesis; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; cellular response to fluid shear stress; renal tubule morphogenesis; microspike assembly; negative regulation of epithelial cell proliferation; cell adhesion; filopodium assembly; actin cytoskeleton organization | |
| MTSS1L | signal transduction; filopodium assembly | |
| MTTP | lipoprotein transport; cholesterol homeostasis; lipoprotein metabolic process; lipid transport; transport; triglyceride metabolic process; lipid metabolic process; small molecule metabolic process; response to calcium ion; protein lipidation | |
| MTURN | - | |
| MTUS1 | - | |
| MTUS2 | - | |
| MUC1 | negative regulation of transcription by competitive promoter binding; anti-apoptosis; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; O-glycan processing; positive regulation of transcription from RNA polymerase II promoter in response to stress; regulation of transcription from RNA polymerase II promoter in response to stress; post-translational protein modification; cellular protein metabolic process; positive regulation of histone H4 acetylation | |
| MUC13 | O-glycan processing; post-translational protein modification; cellular protein metabolic process | |
| MUC15 | O-glycan processing; cellular protein metabolic process; post-translational protein modification | |
| MUC17 | O-glycan processing; cellular homeostasis; cellular protein metabolic process; post-translational protein modification | |
| MUC4 | cellular protein metabolic process; post-translational protein modification; cell adhesion; cell-matrix adhesion; O-glycan processing | |
| MUM1 | DNA repair; chromatin organization | |
| MURC | multicellular organismal development; cell differentiation; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; muscle organ development | |
| MUS81 | DNA repair; DNA recombination | |
| MUT | fatty acid beta-oxidation; post-embryonic development; short-chain fatty acid catabolic process; cellular lipid metabolic process; small molecule metabolic process; homocysteine metabolic process | |
| MUTYH | mismatch repair; depurination; base-excision repair, AP site formation; base-excision repair; DNA repair | |
| MVB12B | - | |
| MVD | cholesterol biosynthetic process; positive regulation of cell proliferation; isoprenoid biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; response to drug; small molecule metabolic process | |
| MVP | protein transport; response to drug; mRNA transport | |
| MX1 | defense response; induction of apoptosis; signal transduction; response to virus; cytokine-mediated signaling pathway; type I interferon-mediated signaling pathway | |
| MX2 | GTP catabolic process; defense response; response to virus; cytokine-mediated signaling pathway; type I interferon-mediated signaling pathway | |
| MXD1 | regulation of transcription, DNA-dependent; multicellular organismal development; cell proliferation | |
| MXI1 | regulation of transcription, DNA-dependent; negative regulation of cell proliferation; cytoplasmic sequestering of transcription factor | |
| MXRA8 | - | |
| MYADM | - | |
| MYB | chromatin remodeling; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; blood coagulation; positive regulation of T-helper cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation | |
| MYBBP1A | positive regulation of cell cycle arrest; signal transduction by p53 class mediator resulting in induction of apoptosis; cellular response to glucose starvation; nucleocytoplasmic transport; regulation of transcription, DNA-dependent | |
| MYBPC1 | cell adhesion; muscle filament sliding | |
| MYBPHL | - | |
| MYC | negative regulation of fibroblast proliferation; positive regulation of metanephric cap mesenchymal cell proliferation; positive regulation of fibroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of monocyte differentiation; fibroblast apoptosis; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; cell cycle arrest; positive regulation of epithelial cell proliferation; chromosome organization; negative regulation of cell division; canonical Wnt receptor signaling pathway; response to growth factor stimulus; positive regulation of DNA biosynthetic process; positive regulation of response to DNA damage stimulus; negative regulation of G2 phase of mitotic cell cycle; cellular response to drug; response to drug; negative regulation of transcription from RNA polymerase II promoter; MAPK cascade; branching involved in ure | |
| MYCBP2 | central nervous system projection neuron axonogenesis; regulation of protein localization; cell morphogenesis involved in neuron differentiation; regulation of cytoskeleton organization; branchiomotor neuron axon guidance; regulation of transcription, DNA-dependent | |
| MYCBPAP | sensory perception of sound; cell differentiation; spermatogenesis; multicellular organismal development; synaptic transmission | |
| MYCL | - | |
| MYCN | regulation of transcription from RNA polymerase II promoter | |
| MYCT1 | - | |
| MYD88 | response to peptidoglycan; response to lipopolysaccharide; positive regulation of interleukin-17 production; positive regulation of interleukin-23 production; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; regulation of cell proliferation; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of growth of symbiont in host; lipopolysaccharide-mediated signaling pathway; cytokine-mediated signaling pathway; immunoglobulin mediated immune response; response to virus; Toll signaling pathway; cell surface receptor signaling pathway; signal transduction; anti-apoptosis; MyD88-dependent toll-like receptor signaling pathway; response to molecule of fungal origin; toll-like receptor signaling pathway; positive regulation of chemokine biosynthetic process; 3'-UTR-mediated mRNA stabilization; innate immune response; type | |
| MYEF2 | transcription, DNA-dependent; myotube differentiation; neuron differentiation | |
| MYEOV | - | |
| MYEOV2 | - | |
| MYF5 | somitogenesis; ossification; regulation of cell-matrix adhesion; regulation of transcription from RNA polymerase II promoter; multicellular organismal development; cartilage condensation; skeletal muscle tissue development; muscle organ development; extracellular matrix organization; muscle cell differentiation; muscle cell fate commitment; camera-type eye development; positive regulation of transcription from RNA polymerase II promoter; embryonic skeletal system morphogenesis; positive regulation of muscle cell differentiation; muscle tissue morphogenesis | |
| MYF6 | muscle tissue morphogenesis; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; skeletal muscle tissue regeneration; muscle cell fate commitment; muscle cell differentiation; skeletal muscle tissue development; muscle organ development; multicellular organismal development; regulation of transcription from RNA polymerase II promoter; somitogenesis | |
| MYH1 | - | |
| MYH10 | substrate-dependent cell migration, cell extension; in utero embryonic development; cytokinesis after mitosis; exocytosis; nuclear migration; axon guidance; brain development; adult heart development; cell proliferation; regulation of cell shape; fourth ventricle development; lateral ventricle development; third ventricle development; cerebellar Purkinje cell layer development; actin cytoskeleton organization; actin filament-based movement; neuromuscular process controlling balance; cardiac myofibril assembly; ventricular cardiac muscle cell development; retina development in camera-type eye; neuron projection development; neuron migration; plasma membrane repair | |
| MYH11 | skeletal muscle myosin thick filament assembly; cardiac muscle fiber development; elastic fiber assembly; metabolic process; axon guidance; smooth muscle contraction; muscle contraction | |
| MYH15 | - | |
| MYH2 | muscle contraction; muscle filament sliding | |
| MYH3 | actin filament-based movement; muscle filament sliding; muscle organ development | |
| MYH4 | muscle contraction; response to activity; actin filament-based movement; muscle filament sliding | |
| MYH6 | canonical Wnt receptor signaling pathway; ventricular cardiac muscle tissue morphogenesis; atrial cardiac muscle tissue morphogenesis; cardiac muscle fiber development; sarcomere organization; regulation of ATPase activity; regulation of heart contraction; BMP signaling pathway; myofibril assembly; actin filament-based movement; regulation of blood pressure; visceral muscle development; adult heart development; striated muscle contraction; muscle contraction; ATP catabolic process; regulation of heart rate; regulation of the force of heart contraction; in utero embryonic development; muscle filament sliding | |
| MYH7 | ventricular cardiac muscle tissue morphogenesis; muscle filament sliding; muscle contraction; response to reactive oxygen species; regulation of heart rate; ATP catabolic process; adult heart development | |
| MYH7B | - | |
| MYH8 | muscle filament sliding; muscle contraction | |
| MYH9 | blood vessel endothelial cell migration; termination of G-protein coupled receptor signaling pathway; leukocyte migration; uropod organization; actin cytoskeleton reorganization; monocyte differentiation; platelet formation; actin filament-based movement; cell-cell adhesion; protein transport; regulation of cell shape; myoblast fusion; axon guidance; integrin-mediated signaling pathway; meiotic metaphase I; membrane protein ectodomain proteolysis; ATP catabolic process; establishment of T cell polarity; in utero embryonic development; angiogenesis; cytokinesis; cell morphogenesis involved in differentiation; meiotic spindle organization; establishment of meiotic spindle localization | |
| MYLK | positive regulation of wound healing; cellular hypotonic response; aorta smooth muscle tissue morphogenesis; positive regulation of calcium ion transport; protein phosphorylation; muscle contraction; smooth muscle contraction; tonic smooth muscle contraction; positive regulation of cell migration; bleb assembly | |
| MYLK2 | striated muscle contraction; regulation of MAPK cascade; skeletal muscle cell differentiation; regulation of muscle filament sliding; protein autophosphorylation; regulation of neuronal synaptic plasticity; positive regulation of fast-twitch skeletal muscle fiber contraction; neuromuscular synaptic transmission; synaptic vesicle transport; peptidyl-threonine phosphorylation; satellite cell differentiation; cardiac muscle tissue morphogenesis; cardiac muscle cell differentiation; regulation of cell cycle; positive regulation of cellular component movement; positive regulation of gene expression; cardiac muscle contraction; water transport | |
| MYLK3 | protein phosphorylation; sarcomere organization; cellular response to interleukin-1; regulation of vascular permeability involved in acute inflammatory response; sarcomerogenesis; positive regulation of sarcomere organization; cardiac myofibril assembly | |
| MYLK4 | - | |
| MYLPF | skeletal muscle tissue development; immune response | |
| MYNN | regulation of transcription, DNA-dependent; transcription, DNA-dependent | |
| MYO15A | inner ear morphogenesis; locomotory behavior; sensory perception of sound | |
| MYO16 | negative regulation of cell proliferation; cerebellum development; negative regulation of S phase of mitotic cell cycle | |
| MYO1A | vesicle localization; sensory perception of sound; cell projection organization; microvillus assembly | |
| MYO1B | actin filament bundle assembly; actin filament-based movement | |
| MYO1C | protein transport; mRNA transport | |
| MYO1D | negative regulation of phosphatase activity | |
| MYO1E | vasculogenesis; in utero embryonic development; kidney development; glomerular filtration; nitrogen compound metabolic process; endocytosis; actin filament-based movement; glomerular basement membrane development; post-embryonic hemopoiesis; platelet-derived growth factor receptor signaling pathway; glomerular visceral epithelial cell development | |
| MYO1F | defense response to Gram-positive bacterium; regulation of innate immune response; neutrophil degranulation; regulation of actin cytoskeleton organization; positive regulation of cell migration; negative regulation of cell adhesion | |
| MYO1G | - | |
| MYO3A | visual perception; response to stimulus; protein autophosphorylation; sensory perception of sound | |
| MYO3B | response to stimulus; visual perception | |
| MYO5A | synaptic transmission; transport; endoplasmic reticulum localization; neuromuscular process controlling balance; synapse organization; developmental pigmentation; long-chain fatty acid biosynthetic process; anagen; myelination; melanin biosynthetic process; melanocyte differentiation; insulin secretion; actin filament-based movement; metabolic process; visual perception; exocytosis; odontogenesis; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; locomotion involved in locomotory behavior; secretory granule localization; melanosome localization; melanosome transport | |
| MYO5B | vesicle-mediated transport; regulation of protein localization; protein transport | |
| MYO5C | - | |
| MYO6 | positive regulation of transcription from RNA polymerase II promoter; regulation of secretion; DNA damage response, signal transduction by p53 class mediator; actin filament-based movement; sensory perception of sound; synaptic transmission; endocytosis; intracellular protein transport | |
| MYO9A | regulation of small GTPase mediated signal transduction; visual perception; small GTPase mediated signal transduction | |
| MYOC | anatomical structure morphogenesis | |
| MYOCD | ventricular cardiac muscle cell differentiation; uterus development; urinary bladder development; cellular component maintenance at cellular level; ductus arteriosus closure; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; positive regulation of cardiac vascular smooth muscle cell differentiation; negative regulation of skeletal muscle cell differentiation; positive regulation of cardiac muscle cell differentiation; positive regulation of cell proliferation; regulation of myoblast differentiation; positive regulation of DNA binding; regulation of histone acetylation; cardiac cell differentiation; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of myotube differentiation; negative regulation of cardiac muscle cell apoptosis; negative regulation of cell proliferation; positive regulation of smooth muscle cell differentiation; transcription from RNA polymerase II promoter; regulation of tra | |
| MYOD1 | protein phosphorylation; regulation of alternative nuclear mRNA splicing, via spliceosome; regulation of transcription from RNA polymerase II promoter; cellular response to oxygen levels; cellular response to glucocorticoid stimulus; cardiac muscle cell differentiation; positive regulation of muscle cell differentiation; skeletal muscle fiber development; positive regulation of transcription from RNA polymerase II promoter; myoblast differentiation; skeletal muscle fiber adaptation; positive regulation of skeletal muscle tissue regeneration; muscle cell fate commitment; muscle cell differentiation; skeletal muscle cell differentiation; myotube differentiation involved in skeletal muscle regeneration; cellular response to starvation; skeletal muscle tissue development; myoblast cell fate determination; muscle organ development; multicellular organismal development | |
| MYOF | cellular response to heat; regulation of vascular endothelial growth factor receptor signaling pathway; blood circulation; muscle contraction; plasma membrane repair | |
| MYOG | cellular response to growth factor stimulus; cellular response to lithium ion; positive regulation of muscle cell differentiation; skeletal muscle fiber development; muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; skeletal muscle tissue development; muscle cell fate commitment; ossification; regulation of transcription, DNA-dependent; multicellular organismal development; muscle organ development | |
| MYOM2 | muscle contraction | |
| MYOM3 | - | |
| MYOT | muscle contraction | |
| MYOZ3 | - | |
| MYPN | sarcomere organization | |
| MYPOP | negative regulation of transcription from RNA polymerase II promoter | |
| MYRF | - | |
| MYRIP | intracellular protein transport | |
| MYSM1 | proteolysis; chromatin modification; histone deubiquitination; positive regulation of transcription, DNA-dependent | |
| MYT1 | regulation of transcription, DNA-dependent; multicellular organismal development; nervous system development; cell differentiation | |
| MZF1 | viral reproduction; regulation of transcription, DNA-dependent | |
| N4BP2 | - | |
| N4BP2L2 | - | |
| N4BP3 | - | |
| NAA10 | internal protein amino acid acetylation; N-terminal protein amino acid acetylation; DNA packaging | |
| NAA15 | positive regulation of transcription, DNA-dependent; multicellular organismal development; cell differentiation; N-terminal protein amino acid acetylation; angiogenesis | |
| NAA20 | - | |
| NAA25 | - | |
| NAA30 | - | |
| NAA40 | - | |
| NAALAD2 | proteolysis | |
| NAALADL1 | proteolysis | |
| NABP2 | - | |
| NACA2 | protein transport | |
| NACC1 | induction of apoptosis; protein homooligomerization; positive regulation of cell proliferation; negative regulation of transcription, DNA-dependent | |
| NADK | vitamin metabolic process; metabolic process; phosphorylation; NAD metabolic process; small molecule metabolic process; ATP metabolic process; water-soluble vitamin metabolic process | |
| NADK2 | - | |
| NAE1 | signal transduction; protein neddylation; regulation of apoptotic process; mitotic cell cycle DNA replication checkpoint; cell cycle; DNA replication | |
| NAGK | carbohydrate phosphorylation; N-acetylglucosamine metabolic process; N-acetylmannosamine metabolic process | |
| NAGLU | lysosome organization; inner ear receptor cell development; retinal rod cell development; locomotor rhythm; middle ear morphogenesis; cerebellar Purkinje cell layer development; metabolic process; nervous system development | |
| NAGPA | carbohydrate metabolic process; protein modification process; protein targeting to lysosome; lysosome organization | |
| NAGS | urea cycle; glutamate metabolic process; cellular amino acid biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| NAIF1 | apoptotic process; induction of apoptosis | |
| NALCN | ion transport; transmembrane transport | |
| NAP1L2 | nucleosome assembly | |
| NAP1L3 | nucleosome assembly | |
| NAP1L4 | nucleosome assembly | |
| NAPA | cellular membrane fusion; brain development; regulation of synaptic vesicle priming; cellular membrane organization; neuron differentiation; synaptic transmission, glutamatergic; SNARE complex disassembly; post-Golgi vesicle-mediated transport; apical protein localization; intracellular protein transport; intra-Golgi vesicle-mediated transport | |
| NAPEPLD | lipid metabolic process; phospholipid catabolic process | |
| NAPRT | vitamin metabolic process; water-soluble vitamin metabolic process; nicotinamide metabolic process; response to oxidative stress; NAD biosynthetic process; nicotinate nucleotide salvage; pyridine nucleotide biosynthetic process; NAD metabolic process; small molecule metabolic process | |
| NARF | - | |
| NARS | asparaginyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; gene expression | |
| NARS2 | gene expression; asparaginyl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| NASP | histone exchange; protein transport; cell proliferation; cell cycle; DNA replication; blastocyst development | |
| NAT10 | - | |
| NAT16 | - | |
| NAT8L | - | |
| NAV1 | neuron migration; microtubule bundle formation; cell differentiation; nervous system development; multicellular organismal development | |
| NAV2 | - | |
| NAV3 | - | |
| NBAS | - | |
| NBEAL1 | - | |
| NBN | regulation of DNA-dependent DNA replication initiation; neuromuscular process controlling balance; regulation of fibroblast proliferation; negative regulation of neuron differentiation; isotype switching; response to drug; positive regulation of kinase activity; DNA duplex unwinding; G2/M transition checkpoint; cell cycle arrest; cell cycle; apoptotic process; double-strand break repair; DNA repair; blastocyst growth; in utero embryonic development; double-strand break repair via homologous recombination; telomere maintenance; DNA damage checkpoint; positive regulation of protein autophosphorylation; mitotic cell cycle G1/S transition checkpoint; DNA damage response, signal transduction by p53 class mediator; mitotic cell cycle G2/M transition DNA damage checkpoint; meiosis; positive regulation of cell proliferation | |
| NCALD | vesicle-mediated transport; synaptic transmission | |
| NCAM2 | cell adhesion; neuron cell-cell adhesion | |
| NCAN | cell adhesion; axon guidance | |
| NCAPD2 | cell division; mitotic chromosome condensation; mitosis; cell cycle | |
| NCAPD3 | mitosis; cell cycle; mitotic chromosome condensation; cell division | |
| NCAPG | cell cycle; mitotic chromosome condensation; cell division; mitosis | |
| NCAPG2 | chromosome condensation; cell division; mitosis; cell cycle; inner cell mass cell proliferation | |
| NCAPH | cell cycle; cell division; mitosis; mitotic chromosome condensation | |
| NCAPH2 | chromosome condensation | |
| NCBP1 | positive regulation of mRNA 3'-end processing; mRNA 3'-end processing; gene silencing by RNA; positive regulation of viral transcription; ncRNA metabolic process; mRNA metabolic process; mRNA processing; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; spliceosomal snRNP assembly; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; termination of RNA polymerase II transcription; mRNA capping; mRNA cleavage; RNA metabolic process; mRNA export from nucleus; regulation of translational initiation; transport; histone mRNA metabolic process; RNA splicing; gene expression; viral reproduction | |
| NCBP3 | - | |
| NCDN | regulation of neuronal synaptic plasticity; bone resorption; neuron projection development | |
| NCEH1 | metabolic process; lipid catabolic process | |
| NCF2 | superoxide metabolic process; innate immune response; respiratory burst; positive regulation of blood pressure; response to hyperoxia; positive regulation of neuron apoptosis; superoxide anion generation; response to drug; response to laminar fluid shear stress; response to lipid; response to progesterone stimulus; response to lipopolysaccharide; response to activity; response to organic cyclic compound; cellular defense response; aging; response to glucose stimulus; cellular response to hormone stimulus | |
| NCK2 | positive regulation of transcription from RNA polymerase II promoter; regulation of translation; actin filament organization; signal transduction; signal complex assembly; epidermal growth factor receptor signaling pathway; regulation of epidermal growth factor-activated receptor activity; axon guidance; negative regulation of cell proliferation; cell migration; lamellipodium assembly; positive regulation of actin filament polymerization; positive regulation of T cell proliferation; T cell activation | |
| NCKAP1 | central nervous system development; apoptotic process | |
| NCKAP1L | positive regulation of neutrophil chemotaxis; positive regulation of CD8-positive, alpha-beta T cell differentiation; negative regulation of myosin-light-chain-phosphatase activity; positive regulation of T cell proliferation; response to chemical stimulus; positive regulation of phosphorylation; response to drug; T cell homeostasis; negative regulation of apoptotic process; positive regulation of CD4-positive, alpha-beta T cell differentiation; positive regulation of protein phosphorylation; positive regulation of B cell differentiation; positive regulation of gamma-delta T cell differentiation; actin polymerization-dependent cell motility; positive regulation of phagocytosis, engulfment; B cell receptor signaling pathway; erythrocyte development; positive regulation of erythrocyte differentiation; positive regulation of lymphocyte differentiation; negative regulation of interleukin-17 production; neutrophil chemotaxis; maintenance of cell polarity; positive regulation of cell adhesion mediated by integrin; | |
| NCKIPSD | NLS-bearing substrate import into nucleus; cytoskeleton organization; signal transduction | |
| NCLN | proteolysis; regulation of signal transduction | |
| NCOA1 | positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; cerebellum development; androgen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter by galactose; response to estradiol stimulus; response to retinoic acid; positive regulation of transcription, DNA-dependent; small molecule metabolic process; cellular lipid metabolic process; cellular response to hormone stimulus; response to progesterone stimulus; estrous cycle phase | |
| NCOA3 | developmental growth; positive regulation of gene expression; histone acetylation; androgen receptor signaling pathway; positive regulation of intracellular estrogen receptor signaling pathway; multicellular organism growth; receptor transactivation; cellular lipid metabolic process; small molecule metabolic process; positive regulation of keratinocyte differentiation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity; vagina development; mammary gland branching involved in thelarche; regulation of RNA biosynthetic process | |
| NCOA5 | regulation of transcription, DNA-dependent | |
| NCOA6 | transcription initiation, DNA-dependent; DNA repair; DNA recombination; DNA replication; labyrinthine layer blood vessel development; positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; cellular lipid metabolic process; positive regulation of transcription, DNA-dependent; glucocorticoid receptor signaling pathway; intracellular estrogen receptor signaling pathway; myeloid cell differentiation; response to hormone stimulus; heart development; brain development; transcription initiation from RNA polymerase II promoter | |
| NCOA7 | cell wall macromolecule catabolic process; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter | |
| NCOR1 | regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone deacetylation; cerebellum development; negative regulation of transcription from RNA polymerase II promoter; chromatin modification; definitive erythrocyte differentiation; spindle assembly; negative regulation of phosphatidylinositol 3-kinase cascade; circadian regulation of gene expression; regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter; regulation of multicellular organism growth; regulation of fatty acid transport; CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; thalamus development; transcription from RNA polymerase II promoter; cholesterol homeostasis; cellular lipid metabolic process; small molecule metabolic process; negative regulation of JNK cascade; regulation of catalytic activity | |
| NCOR2 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; cellular lipid metabolic process; small molecule metabolic process; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter | |
| NCR1 | cellular defense response; natural killer cell activation; signal transduction; regulation of natural killer cell mediated cytotoxicity | |
| NCS1 | negative regulation of calcium ion transport via voltage-gated calcium channel activity; phosphatidylinositol-mediated signaling; positive regulation of exocytosis; regulation of neuron projection development | |
| NCSTN | protein processing; proteolysis; apoptotic process; membrane protein ectodomain proteolysis; Notch signaling pathway; Notch receptor processing; induction of apoptosis by extracellular signals; positive regulation of catalytic activity; membrane protein intracellular domain proteolysis; amyloid precursor protein catabolic process; nerve growth factor receptor signaling pathway | |
| NDC80 | mitotic sister chromatid segregation; cell division; phosphatidylinositol-mediated signaling; attachment of spindle microtubules to kinetochore; mitosis; chromosome segregation; mitotic spindle organization; spindle organization; cell cycle; mitotic cell cycle; mitotic prometaphase; establishment of mitotic spindle orientation; M phase of mitotic cell cycle | |
| NDE1 | nervous system development; G2/M transition of mitotic cell cycle; M phase of mitotic cell cycle; establishment of mitotic spindle orientation; mitotic prometaphase; mitotic cell cycle; multicellular organismal development; cell differentiation; centrosome duplication; cell division; establishment of chromosome localization; cerebral cortex development | |
| NDFIP1 | regulation of lymphocyte differentiation; regulation of myeloid leukocyte differentiation; negative regulation of protein transport; negative regulation of inflammatory response; regulation of isotype switching to IgG isotypes; negative regulation of isotype switching to IgE isotypes; positive regulation of protein catabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of T cell proliferation; negative regulation of interleukin-4 production; negative regulation of transporter activity; positive regulation of protein ubiquitination; negative regulation of gene expression; signal transduction; cellular iron ion homeostasis; negative regulation of type 2 immune response | |
| NDNF | neuron migration; nervous system development; positive regulation of cell-substrate adhesion; positive regulation of neuron projection development; cell growth; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; extracellular matrix organization; negative regulation of neuron apoptosis | |
| NDP | vacuole organization; positive regulation of transcription, DNA-dependent; signal transduction; cell-cell signaling; nervous system development; visual perception; sensory perception of sound; cell proliferation; Wnt receptor signaling pathway; extracellular matrix-cell signaling; response to stimulus; positive regulation of sequence-specific DNA binding transcription factor activity; canonical Wnt receptor signaling pathway; retina vasculature morphogenesis in camera-type eye; placenta development | |
| NDRG1 | DNA damage response, signal transduction by p53 class mediator; peripheral nervous system myelin maintenance; cellular response to hypoxia; mast cell activation; positive regulation of spindle checkpoint; response to metal ion | |
| NDRG2 | Wnt receptor signaling pathway; cell differentiation; negative regulation of smooth muscle cell proliferation; negative regulation of ERK1 and ERK2 cascade; regulation of platelet-derived growth factor production; multicellular organismal development; regulation of vascular endothelial growth factor production; negative regulation of cytokine production; signal transduction; nervous system development | |
| NDRG3 | spermatogenesis; cell differentiation; negative regulation of cell growth | |
| NDST1 | organ morphogenesis; polysaccharide biosynthetic process; protein sulfation; fibroblast growth factor receptor signaling pathway; MAPK cascade; inflammatory response; smoothened signaling pathway; respiratory gaseous exchange; embryo development; heparan sulfate proteoglycan biosynthetic process; embryonic viscerocranium morphogenesis; embryonic neurocranium morphogenesis; midbrain development; forebrain development; glycosaminoglycan metabolic process | |
| NDST2 | heparan sulfate proteoglycan biosynthetic process; cellular process | |
| NDST3 | - | |
| NDST4 | - | |
| NDUFA10 | mitochondrial electron transport, NADH to ubiquinone; nucleobase-containing compound metabolic process; transport; respiratory electron transport chain; response to drug; small molecule metabolic process | |
| NDUFA2 | transport; respiratory electron transport chain; small molecule metabolic process; mitochondrial electron transport, NADH to ubiquinone | |
| NDUFA6 | mitochondrial electron transport, NADH to ubiquinone; transport; response to oxidative stress; respiratory electron transport chain; small molecule metabolic process | |
| NDUFA8 | small molecule metabolic process; respiratory electron transport chain; transport; mitochondrial electron transport, NADH to ubiquinone | |
| NDUFA9 | transport; mitochondrial electron transport, NADH to ubiquinone; sodium ion transport; respiratory electron transport chain; cellular metabolic process; small molecule metabolic process | |
| NDUFAF1 | protein complex assembly; mitochondrial electron transport, NADH to ubiquinone | |
| NDUFAF2 | - | |
| NDUFB10 | mitochondrial electron transport, NADH to ubiquinone; respiratory electron transport chain; small molecule metabolic process; transport | |
| NDUFB4 | small molecule metabolic process; respiratory electron transport chain; mitochondrial electron transport, NADH to ubiquinone; transport; response to oxidative stress | |
| NDUFB5 | small molecule metabolic process; respiratory electron transport chain; mitochondrial electron transport, NADH to ubiquinone; transport | |
| NDUFS1 | reactive oxygen species metabolic process; regulation of mitochondrial membrane potential; ATP metabolic process; respiratory electron transport chain; cellular respiration; ATP synthesis coupled electron transport; small molecule metabolic process; mitochondrial electron transport, NADH to ubiquinone; apoptotic process; transport | |
| NDUFV3 | mitochondrial electron transport, NADH to ubiquinone; transport; respiratory electron transport chain; small molecule metabolic process | |
| NEBL | cardiac muscle thin filament assembly | |
| NECAB2 | - | |
| NEDD4 | cellular response to UV; interspecies interaction between organisms; receptor internalization; neuron projection development; negative regulation of vascular endothelial growth factor receptor signaling pathway; development involved in symbiotic interaction; glucocorticoid receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein ubiquitination; receptor catabolic process; cytokine-mediated signaling pathway; transmission of virus; protein modification process; protein targeting to lysosome; lysosomal transport; nervous system development; negative regulation of sodium ion transport; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; positive regulation of phosphatidylinositol 3-kinase cascade; protein K63-linked ubiquitination; response to calcium ion; progesterone receptor signaling pathway; regulation of dendrite morphogenesis; positive regulation of nucleocytoplasmic transport; positive regu | |
| NEDD9 | signal transduction; cytoskeleton organization; cell cycle; mitosis; cell adhesion; actin filament bundle assembly; regulation of growth; integrin-mediated signaling pathway; cell division | |
| NEFM | - | |
| NEGR1 | cell adhesion | |
| NEIL1 | base-excision repair; nucleotide-excision repair; response to oxidative stress; negative regulation of nuclease activity | |
| NEK10 | - | |
| NEK4 | cell division; mitosis; cell cycle; protein phosphorylation | |
| NEK5 | - | |
| NEK8 | - | |
| NEK9 | cell division; mitosis; cell cycle | |
| NELFA | - | |
| NELFCD | - | |
| NELL1 | induction of apoptosis; cell adhesion; nervous system development; positive regulation of ossification; regulation of osteoblast differentiation | |
| NELL2 | regulation of growth; cell adhesion | |
| NEMF | nuclear export | |
| NEMP1 | - | |
| NENF | positive regulation of MAPK cascade | |
| NEO1 | positive regulation of muscle cell differentiation; muscle cell differentiation; axon guidance; cell adhesion | |
| NES | positive regulation of neural precursor cell proliferation; G2/M transition of mitotic cell cycle; multicellular organismal development; central nervous system development; brain development; response to ionizing radiation; positive regulation of intermediate filament depolymerization; embryonic camera-type eye development; response to nutrient levels; response to drug; negative regulation of apoptotic process; cell projection morphogenesis; stem cell proliferation | |
| NET1 | regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; cellular response to hydrogen peroxide; regulation of cell growth; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals; signal transduction; apoptotic process; cellular response to ionizing radiation; positive regulation of Rho GTPase activity; positive regulation of apoptotic process; regulation of Rho protein signal transduction | |
| NETO1 | visual learning; memory; regulation of long-term neuronal synaptic plasticity | |
| NETO2 | - | |
| NEU2 | sphingolipid metabolic process; positive regulation of myoblast differentiation; response to ethanol; small molecule metabolic process; positive regulation of myotube differentiation; glycosphingolipid metabolic process | |
| NEU4 | sphingolipid metabolic process; glycosphingolipid metabolic process; small molecule metabolic process | |
| NEURL4 | - | |
| NEUROD1 | hindbrain development; camera-type eye development; insulin secretion; signal transduction involved in regulation of gene expression; neurogenesis; cerebellum development; dentate gyrus development; anterior/posterior pattern specification; response to glucose stimulus; multicellular organismal development; nitric oxide mediated signal transduction; pancreatic PP cell fate commitment; pancreatic A cell fate commitment; regulation of intestinal epithelial structure maintenance; positive regulation of transcription from RNA polymerase II promoter; response to drug; enteroendocrine cell differentiation; amacrine cell differentiation; endocrine pancreas development; negative regulation of JAK-STAT cascade; embryonic organ morphogenesis; inner ear development; regulation of insulin secretion; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of cell cycle arrest; positive regulation of transcription regulatory region DNA binding; positive regulation of transcription, DN | |
| NEUROD2 | positive regulation of neuron differentiation; associative learning; neuron development; positive regulation of calcium-mediated signaling; positive regulation of sequence-specific DNA binding transcription factor activity; cellular response to electrical stimulus; cellular response to calcium ion; positive regulation of synapse maturation; negative regulation of synapse maturation; positive regulation of synaptic plasticity; behavioral fear response; regulation of transcription from RNA polymerase II promoter; multicellular organismal development; cell differentiation; cerebellar cortex development; protein ubiquitination; nervous system development | |
| NEUROD6 | multicellular organismal development; regulation of transcription, DNA-dependent; nervous system development; dentate gyrus development; cell differentiation | |
| NF1 | regulation of glial cell differentiation; negative regulation of cell migration; negative regulation of osteoclast differentiation; regulation of bone resorption; regulation of blood vessel endothelial cell migration; positive regulation of neuron apoptosis; pigmentation; negative regulation of MAPK cascade; negative regulation of MAP kinase activity; positive regulation of apoptotic process; negative regulation of transcription factor import into nucleus; wound healing; negative regulation of Rac protein signal transduction; positive regulation of Ras GTPase activity; regulation of synaptic transmission, GABAergic; regulation of Ras GTPase activity; positive regulation of adenylate cyclase activity; regulation of angiogenesis; negative regulation of Ras protein signal transduction; negative regulation of neurotransmitter secretion; negative regulation of fibroblast proliferation; regulation of long-term neuronal synaptic plasticity; sympathetic nervous system development; camera-type eye morphogenesis; negat | |
| NF2 | cell-cell junction organization; lens fiber cell differentiation; positive regulation of stress fiber assembly; negative regulation of JAK-STAT cascade; negative regulation of MAPK cascade; negative regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of tyrosine phosphorylation of Stat3 protein; odontogenesis of dentin-containing tooth; regulation of hippo signaling cascade; actin cytoskeleton organization; negative regulation of cell migration; mesoderm formation; negative regulation of cell-matrix adhesion; negative regulation of protein kinase activity; ectoderm development; negative regulation of DNA replication; negative regulation of cell proliferation; Schwann cell proliferation; negative regulation of cell-cell adhesion | |
| NFASC | protein localization to paranode region of axon; peripheral nervous system development; synapse organization; transmission of nerve impulse; myelination; protein localization to juxtaparanode region of axon; paranodal junction assembly; axon guidance; cell adhesion | |
| NFAT5 | excretion; signal transduction; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| NFATC1 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; intracellular signal transduction; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter | |
| NFATC2 | positive regulation of transcription from RNA polymerase II promoter; B cell receptor signaling pathway; positive regulation of transcription, DNA-dependent; response to drug; response to DNA damage stimulus; cytokine production; regulation of transcription, DNA-dependent; positive regulation of B cell proliferation | |
| NFATC2IP | cytokine production; regulation of transcription, DNA-dependent | |
| NFATC3 | heart development; cellular response to lithium ion; muscle cell development; smooth muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cellular respiration; inflammatory response; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; patterning of blood vessels | |
| NFATC4 | transcription from RNA polymerase II promoter; inflammatory response; cell differentiation | |
| NFE2 | blood circulation; negative regulation of bone mineralization; positive regulation of transcription, DNA-dependent; hemostasis; blood coagulation; multicellular organismal development; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; nucleosome disassembly; cell-cell signaling | |
| NFE2L1 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; heme biosynthetic process; inflammatory response; anatomical structure morphogenesis | |
| NFIA | DNA replication; regulation of transcription, DNA-dependent; viral genome replication | |
| NFIC | positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; DNA replication | |
| NFIL3 | transcription from RNA polymerase II promoter; immune response; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; circadian rhythm | |
| NFKBIB | positive regulation of NF-kappaB transcription factor activity; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; transcription, DNA-dependent; signal transduction; cytoplasmic sequestering of NF-kappaB; Toll signaling pathway; toll-like receptor 1 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; innate immune response; toll-like receptor 2 signaling pathway | |
| NFKBID | inflammatory response; negative regulation of NF-kappaB transcription factor activity; negative regulation of T cell differentiation in thymus; negative regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of thymocyte apoptosis | |
| NFKBIZ | regulation of transcription, DNA-dependent; inflammatory response | |
| NFRKB | DNA repair; DNA recombination; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; inflammatory response | |
| NFS1 | iron incorporation into metallo-sulfur cluster; small molecule metabolic process; molybdopterin cofactor biosynthetic process; water-soluble vitamin metabolic process; sulfur amino acid metabolic process; protein complex assembly; cysteine metabolic process; vitamin metabolic process; Mo-molybdopterin cofactor biosynthetic process | |
| NFX1 | inflammatory response; transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; interspecies interaction between organisms; negative regulation of MHC class II biosynthetic process | |
| NFXL1 | - | |
| NFYA | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter | |
| NFYC | positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; protein folding | |
| NGDN | regulation of translation | |
| NGFR | nerve growth factor receptor signaling pathway; apoptotic process; anti-apoptosis; multicellular organismal development; axon guidance; central nervous system development; induction of apoptosis by extracellular signals; response to wounding; regulation of gene expression; detection of temperature stimulus; nerve development; cell differentiation; hair follicle morphogenesis; membrane protein intracellular domain proteolysis; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of axonogenesis; positive regulation of axonogenesis; negative regulation of hair follicle development; regulation of axonogenesis; negative regulation of muscle organ development; positive regulation of odontogenesis of dentin-containing tooth; skin development; negative regulation of cell cycle; positive regulation of fibroblast proliferation | |
| NGLY1 | glycoprotein catabolic process | |
| NGRN | multicellular organismal development; nervous system development; neuron differentiation | |
| NHLH1 | multicellular organismal development; regulation of transcription, DNA-dependent; central nervous system development; cell differentiation | |
| NHLH2 | regulation of transcription, DNA-dependent; multicellular organismal development; central nervous system development; mating behavior; cell differentiation; ovulation cycle; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity | |
| NHLRC2 | - | |
| NHS | lens development in camera-type eye; cell differentiation | |
| NID1 | cell adhesion; positive regulation of cell-substrate adhesion; cell-matrix adhesion; glomerular basement membrane development | |
| NID2 | cell-matrix adhesion; cell adhesion | |
| NIFK | protein complex assembly; rRNA transcription; negative regulation of phosphatase activity; rRNA metabolic process | |
| NIM1K | - | |
| NIN | centrosome-templated microtubule nucleation; centrosome localization; microtubule anchoring at centrosome | |
| NINJ2 | tissue regeneration; nervous system development; neuron cell-cell adhesion; cell adhesion | |
| NINL | G2/M transition of mitotic cell cycle; mitotic cell cycle | |
| NIPAL1 | ion transport; magnesium ion transport | |
| NIPAL2 | - | |
| NIPBL | positive regulation of multicellular organism growth; cellular protein localization; maintenance of mitotic sister chromatid cohesion; arm morphogenesis; ear morphogenesis; regulation of hair cycle; fat cell differentiation; positive regulation of ossification; negative regulation of transcription, DNA-dependent; embryonic arm morphogenesis; heart morphogenesis; external genitalia morphogenesis; eye morphogenesis; gall bladder development; uterus morphogenesis; face morphogenesis; cognition; embryonic viscerocranium morphogenesis; cellular response to X-ray; regulation of developmental growth; embryonic digestive tract morphogenesis; response to DNA damage stimulus; outflow tract morphogenesis; cell cycle; mitotic sister chromatid cohesion; brain development; sensory perception of sound; regulation of embryonic development; developmental growth; positive regulation of histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; metanephros development | |
| NIPSNAP1 | - | |
| NISCH | actin cytoskeleton organization; apoptotic process; negative regulation of cell migration; cell communication; regulation of synaptic transmission, GABAergic; norepinephrine secretion; Rac protein signal transduction; glucose metabolic process; regulation of blood pressure | |
| NKAIN2 | - | |
| NKAP | Notch signaling pathway; positive regulation of alpha-beta T cell differentiation; negative regulation of transcription, DNA-dependent | |
| NKAPL | - | |
| NKD1 | Wnt receptor signaling pathway | |
| NKD2 | exocytosis; Wnt receptor signaling pathway; transport | |
| NKPD1 | - | |
| NKTR | protein folding | |
| NKX6-2 | positive regulation of cell fate commitment; negative regulation of cell fate commitment; regulation of transcription, DNA-dependent; positive regulation of glial cell differentiation; multicellular organismal development; neuromuscular process controlling balance; oligodendrocyte differentiation; cell differentiation; negative regulation of glial cell differentiation; endocrine pancreas development; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; central nervous system myelination | |
| NLE1 | Notch signaling pathway; inner cell mass cell differentiation | |
| NLGN2 | regulation of synaptic transmission; cell-cell junction maintenance; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; postsynaptic density protein 95 clustering; positive regulation of inhibitory postsynaptic membrane potential; protein localization to synapse; positive regulation of excitatory postsynaptic membrane potential; locomotory exploration behavior; neuromuscular process controlling balance; positive regulation of synaptic transmission, GABAergic; sensory perception of pain; cell-cell adhesion; synapse assembly; neuron cell-cell adhesion; regulation of respiratory gaseous exchange by neurological system process; positive regulation of synaptic transmission, glutamatergic; postsynaptic membrane assembly; presynaptic membrane assembly; gephyrin clustering; terminal button organization; positive regulation of synapse assembly | |
| NLGN3 | social behavior; axon extension; visual learning; receptor-mediated endocytosis; synapse assembly; synapse organization; positive regulation of synapse assembly; rhythmic synaptic transmission; regulation of inhibitory postsynaptic membrane potential; presynaptic membrane assembly; regulation of respiratory gaseous exchange by neurological system process; neuron cell-cell adhesion; cell adhesion | |
| NLGN4X | positive regulation of organ growth; synapse organization; vocalization behavior; brainstem development; social behavior; cell adhesion; presynaptic membrane assembly; negative regulation of excitatory postsynaptic membrane potential; cerebellum development; cell-cell junction organization | |
| NLRC4 | inflammatory response; detection of bacterium; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; defense response to bacterium; activation of cysteine-type endopeptidase activity involved in apoptotic process; interleukin-1 beta secretion; positive regulation of apoptotic process; regulation of cysteine-type endopeptidase activity involved in apoptotic process; innate immune response | |
| NLRC5 | negative regulation of type I interferon production; defense response to virus; positive regulation of interferon-gamma-mediated signaling pathway; negative regulation of NF-kappaB transcription factor activity; positive regulation of MHC class I biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; innate immune response; negative regulation of type I interferon-mediated signaling pathway; positive regulation of type I interferon-mediated signaling pathway; regulation of kinase activity | |
| NLRP1 | induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interleukin-1 beta secretion; regulation of inflammatory response; neuron apoptosis; defense response to bacterium; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; regulation of apoptotic process; response to muramyl dipeptide; innate immune response | |
| NLRP10 | - | |
| NLRP11 | oxidation-reduction process | |
| NLRP12 | regulation of interleukin-18 biosynthetic process; negative regulation of protein autophosphorylation; positive regulation of inflammatory response; negative regulation of I-kappaB kinase/NF-kappaB cascade; release of cytoplasmic sequestered NF-kappaB; negative regulation of signal transduction; negative regulation of interleukin-1 secretion; negative regulation of interleukin-6 biosynthetic process; negative regulation of Toll signaling pathway; negative regulation of cytokine secretion; signal transduction; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interleukin-1 beta secretion | |
| NLRP13 | - | |
| NLRP14 | cell differentiation; multicellular organismal development; spermatogenesis | |
| NLRP2 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interleukin-1 beta secretion | |
| NLRP3 | negative regulation of NF-kappaB transcription factor activity; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; innate immune response; interleukin-1 secretion; positive regulation of interleukin-1 beta secretion; protein oligomerization; defense response to virus; defense response; interleukin-18 production; negative regulation of NF-kappaB import into nucleus; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; inflammatory response; signal transduction; detection of biotic stimulus | |
| NLRP4 | - | |
| NLRP6 | regulation of inflammatory response | |
| NLRP7 | - | |
| NLRP9 | - | |
| NLRX1 | negative regulation of type I interferon production; interspecies interaction between organisms; innate immune response | |
| NMB | signal transduction; cell-cell signaling; neuropeptide signaling pathway | |
| NMBR | G-protein coupled receptor signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; bombesin receptor signaling pathway | |
| NME8 | - | |
| NME9 | UTP biosynthetic process; CTP biosynthetic process; GTP biosynthetic process; cell redox homeostasis | |
| NMNAT2 | NAD metabolic process; NAD biosynthetic process; biosynthetic process; pyridine nucleotide biosynthetic process; small molecule metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process | |
| NMNAT3 | small molecule metabolic process; NAD biosynthetic process; biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process; pyridine nucleotide biosynthetic process; NAD metabolic process; neuroprotection | |
| NMRK2 | - | |
| NMT1 | N-terminal protein myristoylation; N-terminal protein lipidation; in utero embryonic development; apoptotic process; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; protein lipoylation; viral reproduction | |
| NMT2 | protein lipoylation; viral reproduction; egress of virus within host cell; N-terminal protein myristoylation | |
| NMUR2 | regulation of smooth muscle contraction; arachidonic acid secretion; feeding behavior; grooming behavior; central nervous system development; synaptic transmission; cell-cell signaling; neuropeptide signaling pathway; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; reduction of food intake in response to dietary excess; calcium ion transport; response to pain; activation of phospholipase A2 activity by calcium-mediated signaling; calcium-mediated signaling; inositol phosphate-mediated signaling | |
| NOC3L | fat cell differentiation | |
| NOC4L | rRNA processing | |
| NOD1 | activation of MAPK activity; toll-like receptor signaling pathway; positive regulation of dendritic cell antigen processing and presentation; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; defense response; intracellular signal transduction; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; defense response to bacterium; positive regulation of JNK cascade; interleukin-8 biosynthetic process; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; apoptotic process; TRIF-dependent toll-like receptor signaling pathway; defense response to Gram-positive bacterium; positive regulation of NF-kappaB transcription factor activity; protein oligomerization; stress-activated MAPK cascade; positive regulation of ERK1 and ERK2 cascade; nucleotide-binding oligomerization domain containing signaling pathway; MyD88-dependent toll-like receptor signaling pathw | |
| NOD2 | detection of muramyl dipeptide; response to muramyl dipeptide; positive regulation of dendritic cell antigen processing and presentation; MyD88-dependent toll-like receptor signaling pathway; positive regulation of interleukin-1 beta secretion; MyD88-independent toll-like receptor signaling pathway; regulation of inflammatory response; positive regulation of B cell activation; positive regulation of type 2 immune response; defense response; positive regulation of NF-kappaB transcription factor activity; protein oligomerization; positive regulation of oxidoreductase activity; stress-activated MAPK cascade; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of prostaglandin-endoperoxide synthase activity; positive regulation of ERK1 and ERK2 cascade; nucleotide-binding oligomerization domain containing signaling pathway; detection of biotic stimulus; nucleotide-binding oligomerization domain containing 2 signaling pathway; negative regulation of macrophage apoptosis; positive | |
| NODAL | brain development; nervous system development; cell migration involved in gastrulation; determination of left/right symmetry; multicellular organismal development; inhibition of neuroepithelial cell differentiation; heart looping; vasculature development; positive regulation of transcription from RNA polymerase II promoter; digestive tract morphogenesis; tissue morphogenesis; formation of anatomical boundary; digestive system development; embryonic process involved in female pregnancy; SMAD protein signal transduction; left lung morphogenesis; epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification; transforming growth factor beta receptor signaling pathway involved in primitive streak formation; mesendoderm development; axial mesodermal cell fate specification; positive regulation of cell proliferation; cell fate commitment; embryonic cranial skeleton morphogenesis; growth; embryonic heart tube development; floor plate morphogenesis; lung development; stem cell | |
| NOL11 | - | |
| NOL12 | - | |
| NOL3 | mRNA processing; regulation of apoptotic process; anti-apoptosis; RNA splicing | |
| NOL4 | - | |
| NOL4L | - | |
| NOL6 | rRNA processing | |
| NOL7 | - | |
| NOL9 | maturation of 5.8S rRNA | |
| NOLC1 | positive regulation of transcription, DNA-dependent; regulation of protein import into nucleus; box H/ACA snoRNA metabolic process; positive regulation of cell proliferation; mitosis; cell cycle; nucleolus organization; response to osmotic stress; rRNA processing | |
| NONO | DNA recombination; RNA splicing; mRNA processing; regulation of transcription, DNA-dependent; DNA repair | |
| NOP14 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal small subunit biogenesis; rRNA processing | |
| NOP16 | - | |
| NOS1 | blood coagulation; myoblast fusion; response to heat; striated muscle contraction; nitric oxide biosynthetic process; arginine catabolic process; regulation of sodium ion transport; response to hypoxia; regulation of cardiac muscle contraction; positive regulation of histone acetylation; cellular response to growth factor stimulus; negative regulation of calcium ion transport; negative regulation of serotonin uptake; negative regulation of hydrolase activity; positive regulation of vasodilation; positive regulation of transcription, DNA-dependent; negative regulation of potassium ion transport; exogenous drug catabolic process; neurotransmitter biosynthetic process; multicellular organismal response to stress; peptidyl-cysteine S-nitrosylation; negative regulation of calcium ion transport into cytosol | |
| NOS2 | positive regulation of leukocyte mediated cytotoxicity; cellular response to lipopolysaccharide; cellular response to interferon-gamma; defense response to Gram-negative bacterium; regulation of insulin secretion; regulation of cellular respiration; defense response to bacterium; negative regulation of protein catabolic process; response to hypoxia; innate immune response in mucosa; arginine catabolic process; superoxide metabolic process; nitric oxide biosynthetic process; regulation of cell proliferation; positive regulation of killing of cells of other organism; peptidyl-cysteine S-nitrosylation; blood coagulation | |
| NOS3 | smooth muscle hyperplasia; positive regulation of apoptotic process; response to lead ion; negative regulation of platelet activation; response to organic cyclic compound; negative regulation of muscle hyperplasia; negative regulation of calcium ion transport; lung development; positive regulation of guanylate cyclase activity; lipopolysaccharide-mediated signaling pathway; response to estradiol stimulus; response to lipopolysaccharide; response to cytokine stimulus; response to fluid shear stress; response to drug; response to mechanical stimulus; response to amino acid stimulus; negative regulation of potassium ion transport; response to peptide hormone stimulus; endothelial cell migration; small molecule metabolic process; response to ethanol; positive regulation of angiogenesis; positive regulation of vasodilation; nitric oxide metabolic process; negative regulation of smooth muscle cell proliferation; regulation of blood vessel size; regulation of nitric-oxide synthase activity; negative regulation of hy | |
| NOSIP | small molecule metabolic process; nitric oxide metabolic process; regulation of nitric-oxide synthase activity; negative regulation of nitric-oxide synthase activity; negative regulation of catalytic activity | |
| NOSTRIN | regulation of nitric-oxide synthase activity; nitric oxide metabolic process; small molecule metabolic process; endocytosis | |
| NOTCH1 | negative regulation of cell-substrate adhesion; negative regulation of myoblast differentiation; positive regulation of keratinocyte differentiation; positive regulation of endothelial cell differentiation; negative regulation of osteoblast differentiation; positive regulation of apoptotic process; anagen; tissue regeneration; embryonic hindlimb morphogenesis; response to lipopolysaccharide; response to corticosteroid stimulus; organ regeneration; hair follicle morphogenesis; forebrain development; negative regulation of BMP signaling pathway; positive regulation of BMP signaling pathway; lung development; neural tube development; cell differentiation in spinal cord; regulation of somitogenesis; sprouting angiogenesis; positive regulation of epithelial cell proliferation; neuronal stem cell maintenance; negative regulation of canonical Wnt receptor signaling pathway; regulation of epithelial cell proliferation involved in prostate gland development; prostate gland epithelium morphogenesis; negative regulation | |
| NOTCH2 | nervous system development; negative regulation of cell proliferation; multicellular organismal development; Notch receptor processing; Notch signaling pathway; cell cycle arrest; induction of apoptosis; anti-apoptosis; regulation of transcription, DNA-dependent; cell fate determination; organ morphogenesis; gene expression; cell growth; stem cell maintenance; hemopoiesis; cell differentiation; tissue regeneration; positive regulation of Ras protein signal transduction; bone remodeling; regulation of developmental process | |
| NOTCH3 | regulation of transcription, DNA-dependent; Notch signaling pathway; Notch receptor processing; multicellular organismal development; gene expression; forebrain development; tissue regeneration; negative regulation of neuron differentiation; positive regulation of smooth muscle cell proliferation; neuron fate commitment; regulation of developmental process; glomerular capillary formation | |
| NOTUM | - | |
| NOVA1 | synaptic transmission; RNA processing; RNA splicing; locomotory behavior | |
| NOX4 | reactive oxygen species metabolic process; inflammatory response; cell aging; negative regulation of cell proliferation; superoxide anion generation; homocysteine metabolic process; oxidation-reduction process; cell morphogenesis | |
| NOX5 | cytokinesis; angiogenesis; endothelial cell proliferation; ion transport; induction of apoptosis; cell proliferation; regulation of proton transport; proton transport; electron transport chain; superoxide anion generation; regulation of fusion of sperm to egg plasma membrane; cytokine secretion; oxidation-reduction process; positive regulation of reactive oxygen species metabolic process | |
| NOXA1 | positive regulation of catalytic activity; regulation of respiratory burst; regulation of hydrogen peroxide metabolic process; superoxide metabolic process | |
| NOXO1 | superoxide metabolic process; cell communication; regulation of hydrogen peroxide metabolic process; extracellular matrix disassembly; positive regulation of catalytic activity; regulation of respiratory burst | |
| NPAP1 | - | |
| NPAS1 | central nervous system development; behavior; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| NPAS2 | regulation of transcription, DNA-dependent; central nervous system development; cellular lipid metabolic process; small molecule metabolic process; positive regulation of transcription from RNA polymerase II promoter; rhythmic process | |
| NPAS3 | locomotory behavior; social behavior; maternal behavior; positive regulation of transcription, DNA-dependent | |
| NPAS4 | positive regulation of transcription from RNA polymerase II promoter | |
| NPAT | regulation of gene expression; positive regulation of transcription, DNA-dependent; regulation of transcription involved in G1/S phase of mitotic cell cycle; cell cycle | |
| NPBWR1 | G-protein coupled receptor signaling pathway; synaptic transmission; regulation of metabolic process; opioid receptor signaling pathway | |
| NPC1 | autophagy; cholesterol homeostasis; lysosomal transport; bile acid metabolic process; sterol transport; cholesterol efflux | |
| NPC1L1 | sterol transport; cholesterol transport; lipoprotein metabolic process; small molecule metabolic process; intestinal cholesterol absorption; cholesterol biosynthetic process; lipid metabolic process; steroid metabolic process | |
| NPFF | synaptic transmission; neuropeptide signaling pathway | |
| NPFFR2 | G-protein coupled receptor signaling pathway; detection of abiotic stimulus | |
| NPHP1 | signal transduction; excretion; visual behavior; cell-cell adhesion; cell projection organization; actin cytoskeleton organization; retina development in camera-type eye; spermatid differentiation | |
| NPHP3 | lipid metabolic process; Wnt receptor signaling pathway; photoreceptor cell maintenance; maintenance of organ identity; regulation of Wnt receptor signaling pathway, planar cell polarity pathway; negative regulation of canonical Wnt receptor signaling pathway; cilium morphogenesis | |
| NPHS1 | glomerular visceral epithelial cell development; excretion; regulation of excretion; glomerular basement membrane development; cell adhesion; myoblast fusion; skeletal muscle tissue development; muscle organ development; multicellular organismal development; JNK cascade; MAPK cascade | |
| NPL | carbohydrate metabolic process | |
| NPM3 | rRNA processing; rRNA transcription | |
| NPNT | multicellular organismal development; cell differentiation; cell adhesion | |
| NPR2 | regulation of blood pressure; intracellular signal transduction; bone development; cellular response to granulocyte macrophage colony-stimulating factor stimulus; receptor guanylyl cyclase signaling pathway; cell surface receptor signaling pathway; signal transduction; cGMP biosynthetic process; ossification | |
| NPRL2 | negative regulation of kinase activity; protein phosphorylation | |
| NPS | neuropeptide signaling pathway | |
| NPSR1 | - | |
| NPTX1 | axonogenesis involved in innervation; transport; synaptic transmission; central nervous system development | |
| NPTXR | response to hydrogen peroxide | |
| NPVF | sensory perception of pain; neuropeptide signaling pathway; negative regulation of gonadotropin secretion | |
| NPY | central nervous system neuron development; calcium ion transport; cellular component movement; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; synaptic transmission; behavior; sensory perception of taste; negative regulation of blood pressure; positive regulation of appetite; neuron projection development; cerebral cortex development; digestion; adult feeding behavior; cell proliferation; blood circulation; feeding behavior | |
| NPY1R | outflow tract morphogenesis; reduction of cytosolic calcium ion concentration; negative regulation of hormone secretion; positive regulation of vasoconstriction; regulation of multicellular organism growth; response to estradiol stimulus; sensory perception of pain; feeding behavior; locomotory behavior; synaptic transmission; inhibition of adenylate cyclase activity by G-protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; glucose metabolic process; regulation of blood pressure | |
| NPY2R | inhibition of adenylate cyclase activity by G-protein signaling pathway; locomotory behavior; synaptic transmission; neuropeptide signaling pathway; cardiac left ventricle morphogenesis; outflow tract morphogenesis | |
| NPY4R | - | |
| NPY5R | positive regulation of acute inflammatory response; generation of ovulation cycle rhythm; positive regulation of smooth muscle cell proliferation; positive regulation of anti-apoptosis; eating behavior; negative regulation of synaptic transmission, GABAergic; negative regulation of glutamate secretion; synaptic transmission; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; cardiac left ventricle morphogenesis; outflow tract morphogenesis | |
| NR0B1 | steroid biosynthetic process; gene expression; intracellular receptor mediated signaling pathway; adrenal gland development; male sex determination; male gonad development; gonad development; negative regulation of transcription from RNA polymerase II promoter; protein localization; spermatogenesis; response to stress; pituitary gland development; hypothalamus development; Sertoli cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of cell differentiation; response to peptide hormone stimulus; negative regulation of sequence-specific DNA binding transcription factor activity; Leydig cell differentiation; negative regulation of intracellular steroid hormone receptor signaling pathway; response to organic substance | |
| NR1D1 | circadian rhythm; positive regulation of cholesterol homeostasis; cellular response to lipopolysaccharide; gene expression; negative regulation of transcription from RNA polymerase II promoter; intracellular receptor mediated signaling pathway; negative regulation of toll-like receptor 4 signaling pathway; steroid hormone mediated signaling pathway; negative regulation of receptor biosynthetic process | |
| NR1D2 | gene expression; regulation of transcription, DNA-dependent; intracellular receptor mediated signaling pathway | |
| NR1H2 | negative regulation of transcription from RNA polymerase II promoter; cellular lipid metabolic process; gene expression; negative regulation of macrophage derived foam cell differentiation; positive regulation of triglyceride biosynthetic process; positive regulation of cholesterol efflux; positive regulation of lipid storage; negative regulation of cholesterol storage; intracellular receptor mediated signaling pathway; positive regulation of cellular protein metabolic process; negative regulation of lipid transport; positive regulation of cholesterol transport; cholesterol homeostasis; positive regulation of fatty acid biosynthetic process; negative regulation of proteolysis; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; retinoic acid receptor signaling pathway; negative regulation of pinocytosis; positive regulation of lipoprotein lipase activity; lipid homeostasis; positive regulation of secretion of lysosomal enzymes; positive re | |
| NR1H3 | positive regulation of toll-like receptor 4 signaling pathway; negative regulation of macrophage activation; regulation of circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; insulin receptor signaling pathway; gene expression; negative regulation of macrophage derived foam cell differentiation; positive regulation of triglyceride biosynthetic process; cholesterol homeostasis; negative regulation of cholesterol storage; response to progesterone stimulus; positive regulation of cholesterol transport; positive regulation of receptor biosynthetic process; negative regulation of lipid transport; negative regulation of pancreatic juice secretion; positive regulation of cholesterol efflux; positive regulation of cellular protein metabolic process; intracellular receptor mediated signaling pathway; cellular lipid metabolic process; sterol homeostasis; negative regulation of interferon-gamma-mediated signaling pathway; triglyceride homeostasis; negative regulation of secretion of l | |
| NR1H4 | positive regulation of glutamate metabolic process; signal transduction; regulation of cholesterol metabolic process; bile acid metabolic process; regulation of transcription, DNA-dependent; cellular response to organic nitrogen; gene expression; intracellular receptor mediated signaling pathway; nitrogen catabolite activation of transcription from RNA polymerase II promoter; regulation of urea metabolic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; cellular response to acid; regulation of bile acid biosynthetic process | |
| NR1I2 | signal transduction; xenobiotic metabolic process; steroid metabolic process; gene expression; intracellular receptor mediated signaling pathway; exogenous drug catabolic process; drug export; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; xenobiotic transport | |
| NR2C1 | positive regulation of retinoic acid receptor signaling pathway; steroid hormone mediated signaling pathway; gene expression; negative regulation of transcription from RNA polymerase II promoter | |
| NR2F1 | negative regulation of transcription from RNA polymerase II promoter; forebrain development; intracellular receptor mediated signaling pathway; gene expression; signal transduction; regulation of transcription, DNA-dependent; neuron migration | |
| NR2F2 | regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; neuron migration; intracellular receptor mediated signaling pathway; regulation of transcription involved in lymphatic endothelial cell fate commitment; limb development; blood vessel morphogenesis; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cyclin-dependent protein kinase activity; response to estradiol stimulus; forebrain development; negative regulation of endothelial cell proliferation; negative regulation of endothelial cell migration; radial pattern formation; anterior/posterior pattern specification; skeletal muscle tissue development; signal transduction; lipid metabolic process; regulation of transcription, DNA-dependent; lymph vessel development | |
| NR3C1 | anti-apoptosis; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; regulation of gluconeogenesis; negative regulation of vascular permeability; glucocorticoid receptor signaling pathway; glucocorticoid mediated signaling pathway; response to activity; regulation of cell proliferation; response to insulin stimulus; regulation of glucocorticoid biosynthetic process; negative regulation of transforming growth factor beta receptor signaling pathway; adrenal gland development; lung development; chromatin modification; muscle atrophy; signal transduction; positive regulation of glutamate secretion; gene expression; response to radiation; glucocorticoid metabolic process; circadian rhythm; aging; brain development; response to arsenic-containing substance; response to mercury ion; chromatin-mediated maintenance of transcription; response to corticosterone stimulus; mammary gland duct morphogenesis; cellular response to magnesium ion; positive regu | |
| NR3C2 | signal transduction; regulation of transcription, DNA-dependent; gene expression; steroid hormone mediated signaling pathway | |
| NR4A1 | endothelial cell chemotaxis; phosphatidylinositol-mediated signaling; cellular response to vascular endothelial growth factor stimulus; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to fibroblast growth factor stimulus; nerve growth factor receptor signaling pathway; intracellular receptor mediated signaling pathway; gene expression; fibroblast growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; induction of apoptosis; cell migration involved in sprouting angiogenesis; positive regulation of endothelial cell proliferation | |
| NR4A2 | response to amphetamine; neuron maturation; positive regulation of catalytic activity; negative regulation of neuron apoptosis; regulation of respiratory gaseous exchange; positive regulation of transcription from RNA polymerase II promoter; dopaminergic neuron differentiation; dopamine biosynthetic process; regulation of dopamine metabolic process; cellular response to stress; cellular response to extracellular stimulus; response to hypoxia; neuron migration; transcription, DNA-dependent; gene expression; central nervous system neuron differentiation; habenula development; intracellular receptor mediated signaling pathway; central nervous system projection neuron axonogenesis; response to insecticide; death; signal transduction; response to inorganic substance; post-embryonic development; adult locomotory behavior; nervous system development | |
| NR4A3 | gene expression; positive regulation of leukocyte apoptosis; vestibular reflex; neuromuscular process controlling balance; mesoderm formation; axon guidance; hippocampus development; semicircular canal morphogenesis; positive regulation of cell cycle; negative regulation of neuron apoptosis; response to peptide hormone stimulus; steroid hormone mediated signaling pathway; cellular response to stress; organ regeneration; adult behavior | |
| NR5A1 | male gonad development; regulation of steroid biosynthetic process; maintenance of protein location in nucleus; positive regulation of male gonad development; negative regulation of female gonad development; positive regulation of transcription from RNA polymerase II promoter; intracellular receptor mediated signaling pathway; adrenal gland development; cell differentiation; gene expression; tissue development; primary sex determination; cell-cell signaling; luteinization | |
| NR5A2 | positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; bile acid metabolic process; positive regulation of viral genome replication; cholesterol homeostasis; homeostatic process; regulation of cell proliferation; intracellular receptor mediated signaling pathway; gene expression; regulation of transcription, DNA-dependent; embryo development | |
| NR6A1 | intracellular receptor mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; gamete generation; spermatogenesis; cell proliferation; gene expression | |
| NRAP | - | |
| NRAS | negative regulation of neuron apoptosis; leukocyte migration; positive regulation of Rac protein signal transduction; regulation of synaptic transmission, GABAergic; actin cytoskeleton organization; MAPK cascade; activation of MAPKK activity; signal transduction; fibroblast growth factor receptor signaling pathway; visual learning; insulin receptor signaling pathway; positive regulation of cell proliferation; blood coagulation; axon guidance; Ras protein signal transduction; small GTPase mediated signal transduction; epidermal growth factor receptor signaling pathway; regulation of long-term neuronal synaptic plasticity; striated muscle cell differentiation; nerve growth factor receptor signaling pathway | |
| NRCAM | neuron migration; axonogenesis; axon guidance; axonal fasciculation; synapse assembly; central nervous system development; cell-cell adhesion; regulation of axon extension; clustering of voltage-gated sodium channels; positive regulation of neuron differentiation; angiogenesis | |
| NRDE2 | - | |
| NRG1 | activation of transmembrane receptor protein tyrosine kinase activity; negative regulation of secretion; ventricular cardiac muscle cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of cell adhesion; cellular protein complex disassembly; regulation of protein heterodimerization activity; regulation of protein homodimerization activity; wound healing; mammary gland development; positive regulation of cell growth; positive regulation of striated muscle cell differentiation; cardiac muscle cell differentiation; Notch signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase signaling pathway; cell communication; anti-apoptosis; neural crest cell development; negative regulation of cardiac muscle cell apoptosis; embryo development; cell proliferation; nervous system development | |
| NRG2 | signal transduction; embryo development | |
| NRG3 | regulation of cell growth; activation of transmembrane receptor protein tyrosine kinase activity | |
| NRIP1 | ovarian follicle rupture; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; ovulation; androgen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; lipid storage | |
| NRIP3 | proteolysis | |
| NRN1L | - | |
| NRP2 | cell differentiation; neural crest cell migration; negative chemotaxis; semaphorin-plexin signaling pathway; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor signaling pathway; positive regulation of endothelial cell migration; heart development; axon guidance; angiogenesis; nervous system development; multicellular organismal development; cell adhesion; positive regulation of endothelial cell proliferation | |
| NRROS | - | |
| NRXN1 | presynaptic membrane assembly; gamma-aminobutyric acid receptor clustering; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; postsynaptic membrane assembly; N-methyl-D-aspartate receptor clustering; gephyrin clustering; guanylate kinase-associated protein clustering; neuroligin clustering; postsynaptic density protein 95 clustering; receptor localization to synapse; regulation of N-methyl-D-aspartate selective glutamate receptor activity; learning; cell adhesion; axon guidance; calcium-dependent cell-cell adhesion; neuronal signal transduction; synaptic transmission; adult behavior; neuron cell-cell adhesion; social behavior; pigmentation; heterophilic cell-cell adhesion; synaptic vesicle clustering; angiogenesis; establishment of protein localization; neuromuscular process controlling balance; positive regulation of synaptic transmission, glutamatergic; prepulse inhibition; face morphogenesis; vocalization behavior; positive regulation of establishmen | |
| NRXN2 | neuroligin clustering; postsynaptic density protein 95 clustering; gephyrin clustering; postsynaptic membrane assembly; cell adhesion; synaptic transmission; neurotransmitter secretion | |
| NRXN3 | axon guidance; cell adhesion; angiogenesis | |
| NSD1 | negative regulation of transcription from RNA polymerase II promoter; gastrulation with mouth forming second; histone H3-K36 methylation; chromatin modification; histone methylation; histone H4-K20 methylation; positive regulation of transcription, DNA-dependent | |
| NSFL1C | - | |
| NSMCE1 | positive regulation of response to DNA damage stimulus; DNA repair; DNA recombination; protein ubiquitination; intracellular signal transduction | |
| NSMCE2 | DNA recombination; positive regulation of maintenance of mitotic sister chromatid cohesion; double-strand break repair via nonhomologous end joining; DNA repair; double-strand break repair via homologous recombination; telomere maintenance via recombination; cellular senescence; positive regulation of mitotic metaphase/anaphase transition | |
| NSMCE4A | positive regulation of response to DNA damage stimulus | |
| NSMF | - | |
| NSRP1 | developmental process; RNA splicing; nucleocytoplasmic transport; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome | |
| NSUN2 | tRNA processing; tRNA methylation | |
| NSUN7 | - | |
| NT5C1A | purine base metabolic process; nucleobase-containing small molecule metabolic process; purine nucleotide catabolic process; pyrimidine base metabolic process; nucleoside metabolic process; pyrimidine nucleoside catabolic process; nucleotide metabolic process; small molecule metabolic process; adenosine metabolic process | |
| NT5C3A | - | |
| NT5C3B | - | |
| NT5DC2 | - | |
| NT5DC3 | - | |
| NTF3 | axon guidance; signal transduction; cell-cell signaling; neuromuscular synaptic transmission; nervous system development; glial cell fate determination; brain development; peripheral nervous system development; smooth muscle cell differentiation; regulation of synaptic transmission; generation of neurons; neuron development; enteric nervous system development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of glial cell differentiation; negative regulation of neuron apoptosis; myelination; mechanoreceptor differentiation; nerve development; epidermis development | |
| NTM | neuron recognition; cell adhesion | |
| NTN3 | axon guidance; muscle cell differentiation; positive regulation of muscle cell differentiation | |
| NTN4 | axon guidance; neuron remodeling; regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling | |
| NTNG1 | nervous system development; multicellular organismal development; axonogenesis; cell differentiation | |
| NTNG2 | multicellular organismal development; nervous system development; axonogenesis; cell differentiation | |
| NTPCR | - | |
| NTRK1 | nervous system development; transmembrane receptor protein tyrosine kinase signaling pathway; multicellular organismal development; negative regulation of cell proliferation; Ras protein signal transduction; small GTPase mediated signal transduction; activation of phospholipase C activity; activation of adenylate cyclase activity; activation of MAPKK activity; protein phosphorylation; negative regulation of neuron apoptosis; positive regulation of angiogenesis; positive regulation of Ras protein signal transduction; protein autophosphorylation; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; sympathetic nervous system development; positive regulation of NF-kappaB transcription factor activity; axonogenesis involved in innervation; positive regulation of ERK1 and ERK2 cascade; developmental programmed cell death; positive regulation of neuron projection development; cell differentiation; positive regulation of Ras GTPase activity; positive regulation of programmed cell | |
| NTRK2 | protein autophosphorylation; negative regulation of neuron apoptosis; nerve growth factor receptor signaling pathway; positive regulation of axonogenesis; neuron differentiation; central nervous system neuron development; positive regulation of MAPK cascade; regulation of Rac GTPase activity; brain-derived neurotrophic factor receptor signaling pathway; positive regulation of phosphatidylinositol 3-kinase cascade; cerebral cortex development; positive regulation of neuron projection development; positive regulation of gene expression; positive regulation of cell proliferation; learning; nervous system development; neuron migration; transmembrane receptor protein tyrosine kinase signaling pathway; activation of adenylate cyclase activity; multicellular organismal development | |
| NTRK3 | protein autophosphorylation; cell differentiation; response to ethanol; mechanoreceptor differentiation; neuron migration; response to stress; transmembrane receptor protein tyrosine kinase signaling pathway; multicellular organismal development; nervous system development; modulation by virus of host transcription; response to axon injury; cochlea development; cellular response to retinoic acid; negative regulation of cell death; response to corticosterone stimulus; negative regulation of astrocyte differentiation; positive regulation of axon extension involved in regeneration; neuron fate specification | |
| NTS | regulation of blood vessel size; signal transduction | |
| NTSR1 | adult locomotory behavior; synaptic transmission; G-protein coupled receptor signaling pathway | |
| NUAK1 | regulation of cellular senescence; response to DNA damage stimulus; regulation of cell adhesion; regulation of myosin-light-chain-phosphatase activity; regulation of cell proliferation | |
| NUAK2 | actin cytoskeleton organization; cellular response to glucose starvation; protein phosphorylation; negative regulation of apoptotic process | |
| NUBP1 | cell growth; iron-sulfur cluster assembly; cellular iron ion homeostasis | |
| NUCB1 | - | |
| NUCB2 | - | |
| NUDCD1 | - | |
| NUDCD2 | - | |
| NUDCD3 | - | |
| NUDT13 | - | |
| NUDT17 | - | |
| NUDT19 | - | |
| NUDT22 | - | |
| NUDT6 | - | |
| NUF2 | cell division; chromosome segregation; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle | |
| NUMA1 | establishment of mitotic spindle orientation; lung epithelial cell differentiation; nucleus organization; mitotic cell cycle; G2/M transition of mitotic cell cycle; mitotic anaphase | |
| NUMB | nervous system development; multicellular organismal development; axon guidance; lateral ventricle development; neuroblast division in subventricular zone; positive regulation of neurogenesis | |
| NUMBL | cytokine-mediated signaling pathway; multicellular organismal development; nervous system development; neuroblast proliferation; axonogenesis; protein metabolic process; lateral ventricle development; neuroblast division in subventricular zone; positive regulation of dendrite morphogenesis; positive regulation of neurogenesis; adherens junction organization; forebrain development | |
| NUP153 | glucose transport; protein transport; regulation of glucose transport; hexose transport; carbohydrate metabolic process; viral reproduction; cytokine-mediated signaling pathway; small molecule metabolic process; interspecies interaction between organisms; mRNA transport; transmembrane transport | |
| NUP155 | carbohydrate metabolic process; viral reproduction; nucleocytoplasmic transport; hexose transport; regulation of glucose transport; protein transport; glucose transport; cytokine-mediated signaling pathway; transmembrane transport; mRNA transport; small molecule metabolic process | |
| NUP160 | mitotic cell cycle; viral reproduction; glucose transport; protein transport; regulation of glucose transport; hexose transport; M phase of mitotic cell cycle; mitotic prometaphase; mRNA export from nucleus; carbohydrate metabolic process; transmembrane transport; cytokine-mediated signaling pathway; small molecule metabolic process | |
| NUP188 | mRNA transport; cytokine-mediated signaling pathway; viral reproduction; small molecule metabolic process; regulation of glucose transport; protein transport; glucose transport; hexose transport; carbohydrate metabolic process; transmembrane transport | |
| NUP205 | protein import into nucleus, docking; viral reproduction; glucose transport; protein transport; cytokine-mediated signaling pathway; regulation of glucose transport; hexose transport; transmembrane transport; carbohydrate metabolic process; nucleocytoplasmic transport; small molecule metabolic process; mRNA transport | |
| NUP210 | glucose transport; regulation of glucose transport; hexose transport; carbohydrate metabolic process; protein transport; viral reproduction; cytokine-mediated signaling pathway; small molecule metabolic process; transmembrane transport; mRNA transport | |
| NUP210L | - | |
| NUP214 | mRNA export from nucleus; cytokine-mediated signaling pathway; protein import into nucleus; protein export from nucleus; hexose transport; gene expression; regulation of glucose transport; protein transport; glucose transport; viral reproduction; RNA metabolic process; mRNA metabolic process; transmembrane transport; regulation of cell cycle; small molecule metabolic process; carbohydrate metabolic process | |
| NUP35 | cytokine-mediated signaling pathway; carbohydrate metabolic process; hexose transport; small molecule metabolic process; regulation of glucose transport; protein transport; glucose transport; viral reproduction; mRNA transport; transmembrane transport | |
| NUP43 | transmembrane transport; cell division; mitotic prometaphase; carbohydrate metabolic process; regulation of glucose transport; protein transport; glucose transport; hexose transport; chromosome segregation; mitotic cell cycle; M phase of mitotic cell cycle; viral reproduction; cytokine-mediated signaling pathway; small molecule metabolic process; mRNA transport | |
| NUP54 | regulation of glucose transport; hexose transport; protein transport; carbohydrate metabolic process; small molecule metabolic process; protein targeting; glucose transport; viral reproduction; cytokine-mediated signaling pathway; mRNA transport; transmembrane transport | |
| NUP62 | cell surface receptor signaling pathway; transmembrane transport; regulation of signal transduction; mRNA transport; viral reproduction; cell aging; cell death; negative regulation of cell proliferation; negative regulation of Ras protein signal transduction; regulation of glucose transport; cytokine-mediated signaling pathway; protein transport; hexose transport; glucose transport; hormone-mediated signaling pathway; carbohydrate metabolic process; nucleocytoplasmic transport; positive regulation of transcription, DNA-dependent; positive regulation of epidermal growth factor receptor signaling pathway; small molecule metabolic process; regulation of Ras protein signal transduction; negative regulation of MAP kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of programmed cell death; negative regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; transcription, DNA-dependent | |
| NUP85 | carbohydrate metabolic process; transmembrane transport; M phase of mitotic cell cycle; mRNA transport; hexose transport; protein transport; chemotaxis; glucose transport; regulation of glucose transport; mitotic cell cycle; mitotic prometaphase; macrophage chemotaxis; small molecule metabolic process; lamellipodium assembly; cytokine-mediated signaling pathway; viral reproduction | |
| NUP88 | transmembrane transport; mRNA transport; small molecule metabolic process; cytokine-mediated signaling pathway; viral reproduction; glucose transport; protein transport; regulation of glucose transport; hexose transport; carbohydrate metabolic process | |
| NUP93 | mRNA transport; transmembrane transport; small molecule metabolic process; cytokine-mediated signaling pathway; viral reproduction; glucose transport; protein transport; regulation of glucose transport; hexose transport; carbohydrate metabolic process | |
| NUP98 | interspecies interaction between organisms; mRNA transport; transmembrane transport; glucose transport; cytokine-mediated signaling pathway; protein import into nucleus, docking; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; carbohydrate metabolic process; DNA replication; nucleocytoplasmic transport; nuclear pore organization; hexose transport; regulation of glucose transport; protein transport; viral reproduction; small molecule metabolic process | |
| NUPL2 | carbohydrate metabolic process; protein transport; transmembrane transport; cytokine-mediated signaling pathway; regulation of glucose transport; mRNA transport; hexose transport; protein export from nucleus; small molecule metabolic process; glucose transport; viral reproduction | |
| NUPR1 | cell growth; induction of apoptosis | |
| NUTM1 | - | |
| NWD1 | - | |
| NXF1 | gene expression; transport; poly(A)+ mRNA export from nucleus; interspecies interaction between organisms; mRNA export from nucleus | |
| NXF3 | mRNA export from nucleus; poly(A)+ mRNA export from nucleus; transport | |
| NXPE3 | - | |
| NXPE4 | - | |
| NXPH3 | neuropeptide signaling pathway | |
| NXPH4 | neuropeptide signaling pathway | |
| NYAP1 | - | |
| NYX | response to stimulus; visual perception | |
| OAF | - | |
| OAS2 | nucleobase-containing compound metabolic process; purine nucleotide biosynthetic process; RNA catabolic process; immune response; cytokine-mediated signaling pathway; interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway | |
| OASL | type I interferon-mediated signaling pathway; interferon-gamma-mediated signaling pathway; cytokine-mediated signaling pathway; immune response | |
| OCA2 | melanocyte differentiation; melanin biosynthetic process; developmental pigmentation; transmembrane transport; tyrosine transport; cell proliferation; spermatid development; transport; eye pigment biosynthetic process | |
| OCIAD2 | - | |
| ODAM | odontogenesis of dentin-containing tooth; biomineral tissue development | |
| ODC1 | small molecule metabolic process; cellular nitrogen compound metabolic process; response to virus; positive regulation of cell proliferation; polyamine metabolic process; regulation of cellular amino acid metabolic process; kidney development; polyamine biosynthetic process | |
| ODF1 | multicellular organismal development; spermatogenesis; cell differentiation | |
| ODF2 | spermatogenesis; cell differentiation; multicellular organismal development; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| ODF2L | - | |
| ODF3 | multicellular organismal development; spermatogenesis; cell differentiation | |
| ODF3L1 | - | |
| OFD1 | G2/M transition of mitotic cell cycle; mitotic cell cycle; mitosis; centriole replication; cell projection organization; cilium axoneme assembly; cilium morphogenesis; epithelial cilium movement involved in determination of left/right asymmetry; spindle assembly involved in mitosis | |
| OGDH | generation of precursor metabolites and energy; oxidation-reduction process; small molecule metabolic process; cellular nitrogen compound metabolic process; lysine catabolic process; tricarboxylic acid cycle; glycolysis | |
| OGDHL | glycolysis; tricarboxylic acid cycle | |
| OGFR | opioid receptor signaling pathway; regulation of cell growth | |
| OGFRL1 | - | |
| OGT | protein O-linked glycosylation; apoptotic process; induction of apoptosis; signal transduction; response to nutrient; positive regulation of granulocyte differentiation; response to insulin stimulus; positive regulation of catalytic activity; regulation of Rac protein signal transduction; cellular response to retinoic acid; protein homotrimerization; positive regulation of histone H3-K4 methylation; phosphatidylinositol-mediated signaling; regulation of insulin receptor signaling pathway; positive regulation of proteolysis; histone H4-K16 acetylation; histone H4-K8 acetylation; histone H4-K5 acetylation | |
| OIP5 | cell division; CenH3-containing nucleosome assembly at centromere; cell communication; mitosis; cell cycle; nucleosome assembly | |
| OIT3 | - | |
| OLFM3 | - | |
| OLFM4 | cell adhesion | |
| OLFML2A | extracellular matrix organization | |
| OLFML2B | extracellular matrix organization | |
| OLFML3 | multicellular organismal development | |
| OLIG2 | nervous system development; positive regulation of oligodendrocyte differentiation; negative regulation of neuron differentiation; myelination; negative regulation of transcription from RNA polymerase II promoter; multicellular organismal development; spinal cord oligodendrocyte cell fate specification; neuron fate commitment | |
| OLR1 | cell adhesion; leukocyte cell-cell adhesion; blood coagulation; blood circulation; cell death; lipoprotein metabolic process; response to hydrogen peroxide; leukocyte migration; inflammatory response; proteolysis | |
| OMG | negative regulation of axonogenesis; regulation of axonogenesis; regulation of collateral sprouting of intact axon in response to injury; nerve growth factor receptor signaling pathway; neuron projection regeneration; cell adhesion | |
| ONECUT1 | regulation of transcription, DNA-dependent; endoderm development; anatomical structure morphogenesis; B cell differentiation; positive regulation of cell migration; negative regulation of transforming growth factor beta receptor signaling pathway; endocrine pancreas development; positive regulation of transcription, DNA-dependent; cell fate commitment; cilium assembly; glucose metabolic process; epithelial cell development; regulation of cell-matrix adhesion; liver development; positive regulation of transcription from RNA polymerase II promoter; spleen development | |
| OPA1 | axon transport of mitochondrion; GTP catabolic process; mitochondrial fusion; positive regulation of anti-apoptosis; response to stimulus; visual perception; inner mitochondrial membrane organization; mitochondrion organization; apoptotic process; mitochondrial fission | |
| OPA3 | response to stimulus; visual perception | |
| OPCML | cell adhesion; neuron recognition; opioid receptor signaling pathway | |
| OPHN1 | filopodium assembly; positive regulation of Rho GTPase activity; regulation of endocytosis; actin cytoskeleton organization; axon guidance; nervous system development; small GTPase mediated signal transduction; signal transduction; substrate-dependent cell migration, cell extension; regulation of synaptic transmission, glutamatergic; regulation of small GTPase mediated signal transduction; synaptic vesicle endocytosis | |
| OPN1SW | signal transduction; response to stimulus; protein-chromophore linkage; phototransduction; visual perception | |
| OPN3 | phototransduction; protein-chromophore linkage; visual perception; regulation of circadian rhythm; response to stimulus; G-protein coupled receptor signaling pathway; detection of visible light; detection of light stimulus | |
| OPN4 | protein-chromophore linkage; detection of visible light; phototransduction; visual perception; response to stimulus; rhythmic process; regulation of circadian rhythm | |
| OPN5 | response to stimulus; protein-chromophore linkage; phototransduction; visual perception | |
| OPRK1 | inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; synaptic transmission; sensory perception; behavior; viral genome replication; immune response | |
| OPRL1 | G-protein coupled receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; elevation of cytosolic calcium ion concentration; sensory perception | |
| OPTC | - | |
| OPTN | cell death; protein targeting to Golgi; cellular protein localization; Golgi to plasma membrane protein transport; Golgi organization; Golgi ribbon formation; signal transduction | |
| OR10A3 | response to stimulus; detection of chemical stimulus involved in sensory perception of smell; sensory perception of smell | |
| OR10A6 | response to stimulus | |
| OR10A7 | response to stimulus | |
| OR10AG1 | response to stimulus | |
| OR10G7 | response to stimulus | |
| OR10G8 | response to stimulus | |
| OR10H3 | response to stimulus | |
| OR10J1 | sensory perception of chemical stimulus; single fertilization; G-protein coupled receptor signaling pathway; response to stimulus | |
| OR10J3 | response to stimulus | |
| OR10J5 | response to stimulus | |
| OR10K1 | response to stimulus | |
| OR10Q1 | response to stimulus | |
| OR10S1 | response to stimulus | |
| OR10T2 | response to stimulus | |
| OR10V1 | response to stimulus | |
| OR10W1 | response to stimulus | |
| OR10X1 | response to stimulus | |
| OR10Z1 | response to stimulus | |
| OR11G2 | response to stimulus | |
| OR11H4 | response to stimulus | |
| OR11L1 | response to stimulus | |
| OR13A1 | response to stimulus | |
| OR13C3 | response to stimulus | |
| OR13C8 | response to stimulus | |
| OR13D1 | response to stimulus | |
| OR13G1 | response to stimulus | |
| OR13J1 | response to stimulus | |
| OR14C36 | response to stimulus | |
| OR14I1 | response to stimulus | |
| OR1A1 | response to stimulus; detection of chemical stimulus involved in sensory perception of smell; sensory perception of smell | |
| OR1A2 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR1B1 | response to stimulus | |
| OR1C1 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR1D2 | protein import into nucleus, translocation; cellular component movement; chemotaxis; G-protein coupled receptor signaling pathway; single fertilization; sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR1E1 | response to stimulus; detection of chemical stimulus involved in sensory perception of smell; sensory perception of smell | |
| OR1F1 | signal transduction; response to stimulus | |
| OR1I1 | response to stimulus | |
| OR1J1 | response to stimulus | |
| OR1J2 | response to stimulus | |
| OR1J4 | response to stimulus | |
| OR1L1 | response to stimulus | |
| OR1L3 | response to stimulus | |
| OR1L8 | response to stimulus | |
| OR1M1 | response to stimulus | |
| OR1N2 | response to stimulus | |
| OR2A14 | response to stimulus | |
| OR2A2 | response to stimulus | |
| OR2A25 | response to stimulus | |
| OR2A5 | G-protein coupled receptor signaling pathway; response to stimulus | |
| OR2AE1 | response to stimulus | |
| OR2AG1 | response to stimulus | |
| OR2AK2 | response to stimulus | |
| OR2AT4 | response to stimulus | |
| OR2B11 | response to stimulus | |
| OR2B2 | response to stimulus | |
| OR2B6 | response to stimulus | |
| OR2C1 | response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR2C3 | response to stimulus | |
| OR2D3 | response to stimulus | |
| OR2G2 | response to stimulus | |
| OR2G6 | response to stimulus | |
| OR2K2 | response to stimulus | |
| OR2L13 | response to stimulus | |
| OR2L2 | response to stimulus | |
| OR2M3 | response to stimulus | |
| OR2M4 | detection of chemical stimulus involved in sensory perception of smell; response to stimulus; sensory perception of smell | |
| OR2M7 | response to stimulus | |
| OR2T1 | response to stimulus | |
| OR2T10 | response to stimulus | |
| OR2T11 | response to stimulus | |
| OR2T4 | response to stimulus | |
| OR2T8 | response to stimulus | |
| OR2V2 | response to stimulus | |
| OR2W5 | response to stimulus | |
| OR2Y1 | response to stimulus | |
| OR2Z1 | response to stimulus | |
| OR4A16 | response to stimulus | |
| OR4B1 | response to stimulus | |
| OR4C11 | response to stimulus | |
| OR4C15 | response to stimulus | |
| OR4C16 | response to stimulus | |
| OR4C6 | response to stimulus | |
| OR4D1 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR4D11 | response to stimulus | |
| OR4D2 | response to stimulus | |
| OR4D5 | response to stimulus | |
| OR4D9 | response to stimulus | |
| OR4E2 | response to stimulus | |
| OR4F15 | response to stimulus | |
| OR4K1 | response to stimulus | |
| OR4K13 | response to stimulus | |
| OR4K14 | response to stimulus | |
| OR4K17 | response to stimulus | |
| OR4K2 | response to stimulus | |
| OR4L1 | response to stimulus | |
| OR4P4 | response to stimulus | |
| OR4S2 | response to stimulus | |
| OR4X1 | response to stimulus | |
| OR4X2 | response to stimulus | |
| OR51A7 | response to stimulus | |
| OR51B2 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR51B4 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR51B5 | response to stimulus; sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell | |
| OR51D1 | response to stimulus | |
| OR51E1 | response to stimulus | |
| OR51E2 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR51F2 | response to stimulus | |
| OR51I2 | response to stimulus; sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell | |
| OR51L1 | response to stimulus | |
| OR51Q1 | response to stimulus | |
| OR51S1 | response to stimulus | |
| OR51T1 | response to stimulus | |
| OR52A1 | response to stimulus; sensory perception of smell; signal transduction | |
| OR52A5 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR52B4 | response to stimulus | |
| OR52B6 | response to stimulus | |
| OR52D1 | response to stimulus; detection of chemical stimulus involved in sensory perception of smell; sensory perception of smell | |
| OR52E4 | response to stimulus | |
| OR52E8 | response to stimulus | |
| OR52H1 | response to stimulus | |
| OR52J3 | response to stimulus | |
| OR52K1 | response to stimulus | |
| OR52M1 | response to stimulus | |
| OR52N1 | response to stimulus | |
| OR52N2 | response to stimulus | |
| OR52N5 | response to stimulus | |
| OR52R1 | response to stimulus | |
| OR52W1 | response to stimulus | |
| OR56A3 | response to stimulus | |
| OR56B1 | response to stimulus | |
| OR56B4 | response to stimulus | |
| OR5A1 | response to stimulus | |
| OR5A2 | response to stimulus | |
| OR5AC2 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR5AK2 | response to stimulus | |
| OR5AR1 | response to stimulus | |
| OR5AS1 | response to stimulus | |
| OR5AU1 | response to stimulus | |
| OR5B12 | response to stimulus | |
| OR5B2 | response to stimulus | |
| OR5B21 | response to stimulus | |
| OR5B3 | response to stimulus | |
| OR5C1 | response to stimulus | |
| OR5D13 | response to stimulus | |
| OR5D14 | response to stimulus | |
| OR5D16 | response to stimulus | |
| OR5D18 | response to stimulus | |
| OR5F1 | sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; response to stimulus | |
| OR5H2 | response to stimulus | |
| OR5I1 | response to stimulus; signal transduction | |
| OR5J2 | response to stimulus | |
| OR5K1 | response to stimulus | |
| OR5K2 | response to stimulus | |
| OR5K3 | response to stimulus | |
| OR5K4 | response to stimulus | |
| OR5L2 | response to stimulus | |
| OR5M3 | response to stimulus | |
| OR5M9 | response to stimulus | |
| OR5P2 | response to stimulus | |
| OR5P3 | response to stimulus | |
| OR5R1 | response to stimulus | |
| OR5T2 | response to stimulus | |
| OR5T3 | response to stimulus | |
| OR6A2 | detection of chemical stimulus involved in sensory perception of smell; signal transduction; sensory perception of smell; response to stimulus | |
| OR6B1 | response to stimulus | |
| OR6C1 | response to stimulus | |
| OR6C3 | sensory perception of smell; response to stimulus; detection of chemical stimulus involved in sensory perception of smell | |
| OR6C4 | response to stimulus | |
| OR6C6 | response to stimulus | |
| OR6C65 | response to stimulus | |
| OR6C68 | response to stimulus | |
| OR6C74 | response to stimulus | |
| OR6C75 | response to stimulus | |
| OR6C76 | response to stimulus | |
| OR6K2 | response to stimulus | |
| OR6K3 | response to stimulus | |
| OR6K6 | response to stimulus | |
| OR6M1 | response to stimulus | |
| OR6N1 | response to stimulus | |
| OR6N2 | response to stimulus | |
| OR6Q1 | response to stimulus | |
| OR6S1 | response to stimulus | |
| OR6T1 | response to stimulus | |
| OR6X1 | response to stimulus | |
| OR6Y1 | response to stimulus | |
| OR7A17 | response to stimulus | |
| OR7C1 | G-protein coupled receptor signaling pathway; response to stimulus; spermatogenesis | |
| OR7D2 | regulation of transcription, DNA-dependent; response to stimulus | |
| OR7G1 | response to stimulus | |
| OR8B12 | response to stimulus | |
| OR8B4 | response to stimulus | |
| OR8D2 | response to stimulus | |
| OR8D4 | response to stimulus | |
| OR8I2 | response to stimulus | |
| OR8J3 | response to stimulus | |
| OR8K3 | response to stimulus | |
| OR8K5 | response to stimulus | |
| OR9A2 | response to stimulus | |
| OR9A4 | response to stimulus | |
| OR9I1 | response to stimulus | |
| OR9K2 | response to stimulus | |
| OR9Q1 | response to stimulus | |
| OR9Q2 | response to stimulus | |
| ORAI1 | ion transport; positive regulation of calcium ion transport; regulation of calcium ion transport; blood coagulation | |
| ORAI3 | - | |
| ORAOV1 | - | |
| ORC2 | DNA-dependent DNA replication initiation; DNA replication; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint; negative regulation of transcription from RNA polymerase II promoter | |
| ORC4 | DNA replication; DNA-dependent DNA replication initiation; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint | |
| ORC5 | cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; DNA-dependent DNA replication initiation | |
| ORMDL2 | ceramide metabolic process | |
| ORMDL3 | ceramide metabolic process | |
| OS9 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein retention in ER lumen; protein ubiquitination; ER-associated protein catabolic process; response to endoplasmic reticulum stress | |
| OSBP | transport; lipid transport | |
| OSBP2 | lipid transport; transport | |
| OSBPL10 | lipid transport; transport | |
| OSBPL11 | transport; lipid transport | |
| OSBPL1A | cholesterol metabolic process; vesicle-mediated transport; lipid transport | |
| OSBPL2 | lipid transport; transport | |
| OSBPL3 | lipid transport; transport | |
| OSBPL5 | lipid transport; Golgi to plasma membrane transport; transport; cholesterol metabolic process; cholesterol transport | |
| OSBPL6 | transport; lipid transport | |
| OSBPL8 | lipid transport; transport | |
| OSBPL9 | lipid transport; transport | |
| OSCAR | - | |
| OSCP1 | transport | |
| OSER1 | - | |
| OSGEP | tRNA processing; proteolysis | |
| OSGIN2 | germ cell development; meiosis | |
| OSM | response to heat; positive regulation of cell division; positive regulation of peptidyl-serine phosphorylation; regulation of growth; tyrosine phosphorylation of Stat3 protein; tyrosine phosphorylation of Stat5 protein; tyrosine phosphorylation of Stat1 protein; positive regulation of MAPK cascade; negative regulation of meiosis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of hormone secretion; behavioral response to pain; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of cell proliferation; positive regulation of cell proliferation; cell proliferation; peripheral nervous system development; multicellular organismal development; immune response; apoptotic process; positive regulation of acute inflammatory response | |
| OSMR | positive regulation of acute inflammatory response; cell surface receptor signaling pathway; cell proliferation; positive regulation of cell proliferation; response to cytokine stimulus | |
| OSR1 | mesangial cell development; negative regulation of nephron tubule epithelial cell differentiation; odontogenesis; metanephric smooth muscle tissue development; metanephric epithelium development; ureter urothelium development; metanephric mesenchymal cell differentiation; renal vesicle progenitor cell differentiation; posterior mesonephric tubule development; negative regulation of transcription from RNA polymerase II promoter; urogenital system development; specification of anterior mesonephric tubule identity; embryonic digit morphogenesis; specification of posterior mesonephric tubule identity; embryonic hindlimb morphogenesis; positive regulation of gene expression; ureteric bud development; embryonic skeletal joint development; positive regulation of transcription from RNA polymerase II promoter; intermediate mesoderm development; embryonic skeletal limb joint morphogenesis; pronephros development; stem cell differentiation; positive regulation of gastrulation; positive regulation of epithelial cell prol | |
| OSTF1 | ossification; signal transduction | |
| OSTM1 | osteoclast differentiation | |
| OSTN | negative regulation of osteoblast differentiation; ossification; multicellular organismal development; cell differentiation | |
| OTOA | sensory perception of sound | |
| OTOF | cellular membrane fusion; synaptic vesicle exocytosis; sensory perception of sound | |
| OTOP2 | - | |
| OTOP3 | - | |
| OTUB1 | proteolysis; protein K48-linked deubiquitination | |
| OTUD4 | - | |
| OTUD5 | protein K48-linked deubiquitination; protein K63-linked deubiquitination; innate immune response; response to lipopolysaccharide; negative regulation of type I interferon production; proteolysis | |
| OTUD6A | - | |
| OTUD7A | proteolysis | |
| OTUD7B | negative regulation of I-kappaB kinase/NF-kappaB cascade; proteolysis; protein deubiquitination | |
| OTX1 | anterior/posterior pattern specification; inner ear morphogenesis; midbrain development; forebrain development; multicellular organismal development; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| OTX2 | multicellular organismal development; positive regulation of gastrulation; primitive streak formation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of fibroblast growth factor receptor signaling pathway; positive regulation of embryonic development; midbrain development; forebrain development; regulation of smoothened signaling pathway; axon guidance; protein complex assembly; regulation of transcription, DNA-dependent | |
| OVCA2 | response to retinoic acid | |
| OVGP1 | carbohydrate metabolic process; chitin catabolic process; single fertilization; female pregnancy | |
| OXA1L | protein complex assembly; mitochondrial respiratory chain complex I biogenesis; oxidation-reduction process; negative regulation of oxidoreductase activity; protein tetramerization; protein insertion into membrane; mitochondrial proton-transporting ATP synthase complex assembly; mitochondrial respiratory chain complex I assembly; negative regulation of ATPase activity; aerobic respiration | |
| OXGR1 | G-protein coupled receptor signaling pathway | |
| OXR1 | response to oxidative stress; cell wall macromolecule catabolic process | |
| OXSM | acyl-CoA metabolic process; short-chain fatty acid biosynthetic process; medium-chain fatty acid biosynthetic process | |
| OXSR1 | intracellular protein kinase cascade; response to oxidative stress; protein phosphorylation | |
| OXTR | positive regulation of blood pressure; digestive tract development; positive regulation of synapse assembly; positive regulation of synaptic transmission, glutamatergic; maternal process involved in parturition; estrous cycle phase; positive regulation of penile erection; negative regulation of gastric acid secretion; ERK1 and ERK2 cascade; positive regulation of uterine smooth muscle contraction; response to amphetamine; response to peptide hormone stimulus; response to organic cyclic compound; positive regulation of norepinephrine secretion; memory; lactation; regulation of digestive system process; female pregnancy; heart development; elevation of cytosolic calcium ion concentration; cell surface receptor signaling pathway; muscle contraction; suckling behavior; telencephalon development; sleep; positive regulation of synaptic transmission, GABAergic; response to estradiol stimulus; response to progesterone stimulus; response to anoxia; response to cytokine stimulus; social behavior; response to cocaine; r | |
| P2RX1 | response to stimulus; signal transduction; protein homooligomerization; protein heterooligomerization; regulation of calcium ion transport; calcium ion transmembrane transport; serotonin secretion by platelet; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of ion transport; insemination; blood coagulation; regulation of blood pressure; death; regulation of action potential in neuron; platelet activation; response to ATP; cation transport; ion transport; transport; regulation of vascular smooth muscle contraction; synaptic transmission, glutamatergic; purinergic nucleotide receptor signaling pathway; ceramide biosynthetic process | |
| P2RX2 | cation transport; positive regulation of calcium ion transport into cytosol; purinergic nucleotide receptor signaling pathway; positive regulation of calcium-mediated signaling; protein homooligomerization | |
| P2RX4 | regulation of excitatory postsynaptic membrane potential; relaxation of cardiac muscle; regulation of cardiac muscle contraction; positive regulation of calcium ion transport; membrane depolarization; protein homooligomerization; vasodilation; positive regulation of calcium-mediated signaling; regulation of apoptotic process; tissue homeostasis; regulation of sodium ion transport; transport; ion transport; response to stress; signal transduction; regulation of blood pressure; positive regulation of calcium ion transport into cytosol; negative regulation of cardiac muscle hypertrophy; regulation of action potential in neuron; sensory perception of pain; positive regulation of prostaglandin secretion; response to ATP; response to fluid shear stress; purinergic nucleotide receptor signaling pathway; endothelial cell activation; positive regulation of nitric oxide biosynthetic process | |
| P2RY1 | brain development; positive regulation of ion transport; eating behavior; positive regulation of hormone secretion; negative regulation of binding; positive regulation of penile erection; response to growth factor stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; regulation of vasodilation; positive regulation of inositol trisphosphate biosynthetic process; platelet activation; sensory perception of pain; negative regulation of norepinephrine secretion; regulation of receptor activity; aging; response to mechanical stimulus; blood coagulation | |
| P2RY12 | blood coagulation; hemostasis; protein kinase B signaling cascade; positive regulation of ion transport; platelet activation; G-protein signaling, coupled to cAMP nucleotide second messenger | |
| P2RY14 | G-protein coupled receptor signaling pathway; immune response | |
| P2RY2 | activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; cellular response to purine-containing compound; cellular response to interleukin-1; response to growth factor stimulus; positive regulation of penile erection; wound healing; cellular ion homeostasis; elevation of cytosolic calcium ion concentration; aging; embryo development; positive regulation of neuron projection development; positive regulation of smooth muscle cell migration; sensory perception of pain; negative regulation of ossification; positive regulation of prostaglandin secretion; positive regulation of chemokine production; regulation of vasodilation | |
| P2RY4 | transepithelial chloride transport; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger | |
| P2RY6 | activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger | |
| P3H1 | cell growth; negative regulation of cell proliferation | |
| P3H2 | negative regulation of cell proliferation; peptidyl-proline hydroxylation; collagen metabolic process | |
| P3H4 | synaptonemal complex assembly | |
| P4HA1 | collagen fibril organization; peptidyl-proline hydroxylation to 4-hydroxy-L-proline | |
| P4HB | lipoprotein metabolic process; cell redox homeostasis; small molecule metabolic process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; glycerol ether metabolic process; lipid metabolic process | |
| P4HTM | - | |
| PA2G4 | rRNA processing; regulation of translation; cell cycle arrest; cell proliferation; cellular process; negative regulation of transcription, DNA-dependent | |
| PAAF1 | interspecies interaction between organisms | |
| PABPC1 | mRNA metabolic process; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA metabolic process; gene expression; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA splicing; mRNA stabilization; translational initiation; cellular protein metabolic process; translation; positive regulation of translation; mRNA polyadenylation; nuclear mRNA splicing, via spliceosome; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | |
| PABPC4 | RNA processing; RNA catabolic process; translation; blood coagulation | |
| PABPC5 | - | |
| PACRG | - | |
| PACRGL | - | |
| PACS1 | protein targeting to Golgi; protein targeting to plasma membrane; regulation of defense response to virus by virus; viral reproduction; positive regulation of protein binding; cellular protein localization; interspecies interaction between organisms | |
| PACSIN1 | negative regulation of endocytosis; protein phosphorylation; cytoskeleton organization; endocytosis | |
| PACSIN3 | positive regulation of membrane protein ectodomain proteolysis; negative regulation of endocytosis | |
| PADI2 | protein modification process; peptidyl-citrulline biosynthetic process from peptidyl-arginine | |
| PADI3 | peptidyl-citrulline biosynthetic process from peptidyl-arginine; protein modification process | |
| PADI4 | regulation of transcription, DNA-dependent; peptidyl-citrulline biosynthetic process from peptidyl-arginine; chromatin modification; protein modification process | |
| PAF1 | histone monoubiquitination; histone H2B ubiquitination; regulation of transcription, DNA-dependent | |
| PAFAH1B2 | lipid catabolic process; lipid metabolic process | |
| PAFAH1B3 | lipid catabolic process; nervous system development; lipid metabolic process | |
| PAGR1 | - | |
| PAIP2 | negative regulation of translational initiation; regulation of translation | |
| PAK1 | negative regulation of cell proliferation involved in contact inhibition; MAPK cascade; protein phosphorylation; apoptotic process; axon guidance; T cell costimulation; actin cytoskeleton reorganization; positive regulation of peptidyl-serine phosphorylation; positive regulation of intracellular estrogen receptor signaling pathway; wound healing; positive regulation of JUN kinase activity; protein autophosphorylation; branching morphogenesis of a tube; neuron projection morphogenesis; T cell receptor signaling pathway; positive regulation of stress fiber assembly | |
| PAK1IP1 | negative regulation of signal transduction | |
| PAK3 | MAPK cascade; activation of MAPK activity; multicellular organismal development; axonogenesis; dendrite development; regulation of actin filament polymerization; synapse organization; dendritic spine morphogenesis | |
| PAK4 | cellular component movement; apoptotic process; cell proliferation; cell growth; signal transduction; cell migration; protein phosphorylation; cytoskeleton organization; cell cycle | |
| PAK6 | cytoskeleton organization; regulation of transcription, DNA-dependent; apoptotic process | |
| PAK7 | cell growth; apoptotic process; anti-apoptosis; cytoskeleton organization; signal transduction; cell proliferation; cell migration | |
| PALB2 | double-strand break repair via homologous recombination; DNA repair; DNA recombination | |
| PALD1 | - | |
| PALLD | cytoskeleton organization | |
| PALM | protein localization; cellular component movement; cytoskeleton organization; regulation of cell shape; negative regulation of adenylate cyclase activity; synapse maturation; negative regulation of dopamine receptor signaling pathway; positive regulation of dendritic spine development; cellular response to electrical stimulus; protein targeting to plasma membrane; positive regulation of filopodium assembly | |
| PALM2 | regulation of cell shape | |
| PALMD | regulation of cell shape | |
| PAM | central nervous system development; limb development; response to glucocorticoid stimulus; response to copper ion; response to drug; response to estradiol stimulus; response to pH; heart development; peptide metabolic process; protein modification process; response to hypoxia | |
| PAMR1 | - | |
| PAN2 | mRNA metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; RNA metabolic process; ubiquitin-dependent protein catabolic process; gene expression; nuclear-transcribed mRNA poly(A) tail shortening | |
| PAN3 | RNA metabolic process; mRNA metabolic process; gene expression; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | |
| PANK1 | coenzyme A biosynthetic process; pantothenate metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; small molecule metabolic process; coenzyme biosynthetic process | |
| PANK2 | vitamin metabolic process; pantothenate metabolic process; water-soluble vitamin metabolic process; cell death; coenzyme biosynthetic process; coenzyme A biosynthetic process; small molecule metabolic process | |
| PANK4 | coenzyme A biosynthetic process | |
| PANX1 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; innate immune response; positive regulation of interleukin-1 beta secretion; protein hexamerization; positive regulation of cytokine secretion; calcium ion transmembrane transport; positive regulation of interleukin-1 alpha secretion; cation transport; response to ATP; calcium ion transport; synaptic transmission | |
| PANX2 | ion transport; synaptic transmission; protein hexamerization | |
| PAOX | xenobiotic metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; polyamine metabolic process; polyamine biosynthetic process; polyamine catabolic process | |
| PAPD4 | mRNA processing; RNA polyadenylation; histone mRNA catabolic process | |
| PAPLN | - | |
| PAPOLG | mRNA processing; transcription, DNA-dependent; RNA polyadenylation | |
| PAPPA | proteolysis; cell differentiation; metabolic process; female pregnancy | |
| PAPPA2 | regulation of cell growth; cell differentiation; proteolysis | |
| PAPSS1 | sulfate assimilation; skeletal system development; xenobiotic metabolic process; small molecule metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process | |
| PAPSS2 | sulfate assimilation; skeletal system development; xenobiotic metabolic process; small molecule metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process | |
| PAQR3 | - | |
| PAQR4 | - | |
| PAQR9 | - | |
| PARD3 | protein targeting to membrane; protein complex assembly; cell cycle; axonogenesis; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; establishment of epithelial cell polarity; tight junction assembly; establishment or maintenance of cell polarity; cell-cell junction organization; cell junction assembly; asymmetric cell division | |
| PARD3B | cell division; cell cycle | |
| PARD6A | viral reproduction; cell cycle; cell junction assembly; cell-cell junction organization; cell-cell junction maintenance; cell division; tight junction assembly | |
| PARD6B | cell-cell junction organization; tight junction assembly; cell division; cell junction assembly; regulation of cell migration; axonogenesis; establishment or maintenance of cell polarity; protein complex assembly; cell cycle; cell-cell junction assembly | |
| PARD6G | cell junction assembly; cell cycle; cell-cell junction organization; cell division; tight junction assembly | |
| PARK2 | protein polyubiquitination; dopamine metabolic process; mitochondrion degradation; negative regulation of protein phosphorylation; startle response; ubiquitin-dependent protein catabolic process; protein monoubiquitination; central nervous system development; learning; cell death; adult locomotory behavior; regulation of autophagy; protein metabolic process; negative regulation of actin filament bundle assembly; synaptic transmission, glutamatergic; norepinephrine metabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of reactive oxygen species metabolic process; negative regulation of release of cytochrome c from mitochondria; neuron death; protein K48-linked ubiquitination; aggresome assembly; protein K63-linked ubiquitination; negative regulation of cell death; protein autoubiquitination; dopamine uptake; regulation of neurotransmitter secretion; protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| PARL | proteolysis | |
| PARP1 | protein poly-ADP-ribosylation; DNA damage response, detection of DNA damage; regulation of growth rate; cellular response to insulin stimulus; protein autoprocessing; protein ADP-ribosylation; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; base-excision repair; DNA repair; telomere maintenance | |
| PARP10 | regulation of chromatin assembly; protein poly-ADP-ribosylation; negative regulation of fibroblast proliferation | |
| PARP15 | regulation of transcription, DNA-dependent | |
| PARP16 | - | |
| PARP2 | base-excision repair; DNA repair; protein ADP-ribosylation; metabolic process | |
| PARP4 | response to drug; protein ADP-ribosylation; protein modification process; DNA repair; transport; inflammatory response; response to DNA damage stimulus; cell death | |
| PARP6 | - | |
| PARP8 | - | |
| PARP9 | regulation of response to interferon-gamma; cell migration | |
| PARVB | cell adhesion; cell junction assembly | |
| PARVG | cell-matrix adhesion; cell adhesion | |
| PASD1 | - | |
| PASK | protein phosphorylation; negative regulation of glycogen biosynthetic process; regulation of energy homeostasis; positive regulation of translation; regulation of glucagon secretion; protein autophosphorylation; regulation of respiratory gaseous exchange | |
| PATZ1 | male gonad development; T cell differentiation; negative regulation of transcription, DNA-dependent; spermatogenesis; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| PAWR | apoptotic process; induction of apoptosis; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; actin filament bundle assembly; negative regulation of cell proliferation; negative regulation of B cell proliferation; interleukin-2 biosynthetic process; negative regulation of T cell proliferation; positive regulation of amyloid precursor protein biosynthetic process; positive regulation of apoptotic process; negative regulation of T cell receptor signaling pathway | |
| PAX1 | parathyroid gland development; skeletal system development; somitogenesis; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; pattern specification process; CD4-positive, alpha-beta T cell differentiation; CD8-positive, alpha-beta T cell differentiation; positive regulation of transcription from RNA polymerase II promoter; thymus development; bone morphogenesis; sclerotome development | |
| PAX2 | stem cell differentiation; positive regulation of transcription, DNA-dependent; negative regulation of cytolysis; positive regulation of transcription from RNA polymerase II promoter; pronephros development; brain morphogenesis; metanephric mesenchyme development; ureter maturation; mesodermal cell fate specification; visual perception; glial cell differentiation; optic nerve development; optic nerve morphogenesis; optic nerve structural organization; vestibulocochlear nerve formation; regulation of metanephros size; negative regulation of transcription, DNA-dependent; pronephric field specification; inner ear morphogenesis; camera-type eye development; negative regulation of apoptotic process; negative regulation of programmed cell death; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; protein kinase B signaling cascade; metanephric epithelium development; positive regulation of metanephric DCT cell differentiation; negative regulation of reactive oxygen species met | |
| PAX3 | neural crest cell migration; mammary gland specification; neuron fate commitment; developmental pigmentation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; neural tube development; spinal cord association neuron differentiation; cell migration; organ morphogenesis; positive regulation of cell proliferation; sensory perception of sound; muscle organ development; heart development; multicellular organismal development; apoptotic process; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; neural tube closure; negative regulation of transcription from RNA polymerase II promoter | |
| PAX4 | multicellular organismal development; endocrine pancreas development; cell differentiation; organ morphogenesis | |
| PAX5 | negative regulation of histone H3-K9 methylation; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; humoral immune response; multicellular organismal development; spermatogenesis; nervous system development; organ morphogenesis; cell differentiation | |
| PAX6 | eye development; cornea development in camera-type eye; iris morphogenesis; negative regulation of neurogenesis; neuron fate commitment; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; glucose homeostasis; cell differentiation; protein ubiquitination; positive regulation of gene expression; response to wounding; organ morphogenesis; blood vessel development; pancreatic A cell development; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; multicellular organismal development; central nervous system development; visual perception | |
| PAX7 | muscle tissue morphogenesis; cartilage development; multicellular organismal development; embryonic skeletal system development; neuron fate commitment; skeletal muscle tissue regeneration; dorsal/ventral neural tube patterning; spinal cord association neuron differentiation; satellite cell commitment; anatomical structure morphogenesis; skeletal muscle tissue development; anti-apoptosis; regulation of transcription, DNA-dependent | |
| PAX8 | positive regulation of thyroid hormone generation; metanephric comma-shaped body morphogenesis; pronephros development; cellular response to gonadotropin stimulus; otic vesicle development; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; mesonephric tubule development; metanephric collecting duct development; metanephric epithelium development; metanephric distal convoluted tubule development; urogenital system development; metanephric S-shaped body morphogenesis; metanephric nephron tubule formation; negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis; regulation of metanephric nephron tubule epithelial cell differentiation; positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of metanephric DCT cell differentiation; regulation of thyroid-stimulating hormone secretion; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA poly | |
| PAX9 | cellular response to growth factor stimulus; regulation of transcription, DNA-dependent; face morphogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of odontogenesis; endoderm development; multicellular organismal development | |
| PAXBP1 | - | |
| PBDC1 | - | |
| PBK | protein phosphorylation; mitosis | |
| PBLD | biosynthetic process | |
| PBRM1 | negative regulation of cell proliferation; mitosis; chromatin remodeling; regulation of transcription, DNA-dependent | |
| PBX4 | transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent | |
| PBXIP1 | cell differentiation; negative regulation of transcription, DNA-dependent; multicellular organismal development | |
| PC | lipid biosynthetic process; small molecule metabolic process; oxaloacetate metabolic process; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process; pyruvate metabolic process | |
| PCBP2 | nuclear mRNA splicing, via spliceosome; RNA splicing; response to virus; gene expression; mRNA metabolic process; negative regulation of type I interferon production; proteasomal ubiquitin-dependent protein catabolic process; innate immune response; negative regulation of defense response to virus | |
| PCBP3 | mRNA metabolic process | |
| PCCA | short-chain fatty acid catabolic process; fatty acid beta-oxidation; small molecule metabolic process; cellular lipid metabolic process | |
| PCCB | small molecule metabolic process; cellular lipid metabolic process; short-chain fatty acid catabolic process; fatty acid beta-oxidation | |
| PCDH1 | nervous system development; cell-cell signaling; homophilic cell adhesion; cell adhesion | |
| PCDH10 | homophilic cell adhesion; cell adhesion | |
| PCDH12 | cell adhesion; neuron recognition; homophilic cell adhesion | |
| PCDH15 | cell adhesion; homophilic cell adhesion; sensory perception of sound; photoreceptor cell maintenance; sensory perception of light stimulus; equilibrioception | |
| PCDH17 | cell adhesion; homophilic cell adhesion | |
| PCDH18 | brain development; cell adhesion; homophilic cell adhesion | |
| PCDH19 | homophilic cell adhesion; cell adhesion | |
| PCDH20 | cell adhesion; homophilic cell adhesion | |
| PCDH7 | homophilic cell adhesion; cell adhesion | |
| PCDH8 | cell adhesion; somitogenesis; homophilic cell adhesion; cell-cell signaling; synaptic transmission; morphogenesis of embryonic epithelium | |
| PCDH9 | cell adhesion; homophilic cell adhesion | |
| PCDHA1 | nervous system development; homophilic cell adhesion; cell adhesion | |
| PCDHA13 | cell adhesion; homophilic cell adhesion | |
| PCDHA2 | nervous system development; cell adhesion; homophilic cell adhesion | |
| PCDHA3 | nervous system development; homophilic cell adhesion; cell adhesion | |
| PCDHA4 | nervous system development; homophilic cell adhesion; cell adhesion | |
| PCDHA5 | nervous system development; homophilic cell adhesion; cell adhesion | |
| PCDHAC1 | homophilic cell adhesion; cell adhesion; nervous system development | |
| PCDHAC2 | nervous system development; cell adhesion; homophilic cell adhesion | |
| PCDHB1 | homophilic cell adhesion; cell adhesion | |
| PCDHB10 | homophilic cell adhesion; synaptic transmission; calcium-dependent cell-cell adhesion; cell adhesion; synapse assembly | |
| PCDHB11 | cell adhesion; homophilic cell adhesion; calcium-dependent cell-cell adhesion; nervous system development; synaptic transmission; synapse assembly | |
| PCDHB12 | cell adhesion; homophilic cell adhesion; nervous system development | |
| PCDHB14 | cell adhesion; homophilic cell adhesion; calcium-dependent cell-cell adhesion; synaptic transmission; synapse assembly | |
| PCDHB15 | nervous system development; homophilic cell adhesion; cell adhesion | |
| PCDHB16 | calcium-dependent cell-cell adhesion; synapse assembly; homophilic cell adhesion; synaptic transmission; cell adhesion | |
| PCDHB2 | homophilic cell adhesion; cell adhesion; synaptic transmission; nervous system development; synapse assembly; calcium-dependent cell-cell adhesion | |
| PCDHB3 | cell adhesion; homophilic cell adhesion; synaptic transmission; nervous system development; synapse assembly; calcium-dependent cell-cell adhesion | |
| PCDHB4 | synapse assembly; cell adhesion; homophilic cell adhesion; synaptic transmission; calcium-dependent cell-cell adhesion; nervous system development | |
| PCDHGA1 | homophilic cell adhesion; cell adhesion | |
| PCDHGA12 | cell adhesion; homophilic cell adhesion | |
| PCDHGA2 | cell adhesion; homophilic cell adhesion | |
| PCDHGC3 | cell adhesion; calcium-dependent cell-cell adhesion; homophilic cell adhesion | |
| PCDHGC4 | cell adhesion; homophilic cell adhesion | |
| PCDHGC5 | cell adhesion; homophilic cell adhesion | |
| PCED1A | - | |
| PCED1B | - | |
| PCGF1 | regulation of transcription, DNA-dependent; histone H2A monoubiquitination | |
| PCGF6 | negative regulation of transcription, DNA-dependent | |
| PCID2 | spleen development; positive regulation of transcription, DNA-dependent; regulation of mRNA stability; positive regulation of mitotic cell cycle spindle assembly checkpoint; positive regulation of B cell differentiation; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity | |
| PCIF1 | negative regulation of phosphatase activity | |
| PCK1 | carbohydrate metabolic process; gluconeogenesis; response to activity; response to insulin stimulus; glucose homeostasis; small molecule metabolic process; glycerol biosynthetic process from pyruvate; lipid metabolic process; internal protein amino acid acetylation; oxaloacetate metabolic process; glucose metabolic process | |
| PCK2 | response to glucocorticoid stimulus; small molecule metabolic process; oxaloacetate metabolic process; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process | |
| PCMTD2 | protein modification process | |
| PCNT | cilium assembly; neural precursor cell proliferation; brain morphogenesis; multicellular organism growth; limb morphogenesis; olfactory bulb development; cerebellar cortex morphogenesis; apoptotic process; neuron migration; in utero embryonic development; mitotic cell cycle; spindle organization; microtubule cytoskeleton organization; G2/M transition of mitotic cell cycle | |
| PCNX | - | |
| PCOLCE2 | positive regulation of peptidase activity | |
| PCSK2 | islet amyloid polypeptide processing; enkephalin processing; insulin processing; protein autoprocessing; nervous system development; proteolysis | |
| PCSK4 | binding of sperm to zona pellucida; proteolysis; acrosome reaction; fertilization; sperm capacitation | |
| PCSK5 | embryo implantation; kidney development; renin secretion into blood stream; signal peptide processing; proteolysis; cell-cell signaling; embryonic skeletal system development; embryonic digestive tract development; nerve growth factor receptor signaling pathway; peptide biosynthetic process; cytokine biosynthetic process; limb morphogenesis; nerve growth factor processing; heart development; anterior/posterior pattern specification; protein processing; peptide hormone processing; viral assembly, maturation, egress, and release; respiratory tube development | |
| PCSK9 | cellular response to insulin stimulus; regulation of low-density lipoprotein particle receptor catabolic process; low-density lipoprotein particle receptor catabolic process; neuron differentiation; neurogenesis; steroid metabolic process; lysosomal transport; regulation of receptor activity; protein autoprocessing; positive regulation of neuron apoptosis; negative regulation of catalytic activity; cholesterol homeostasis; lipoprotein metabolic process; triglyceride metabolic process; proteolysis; positive regulation of receptor internalization; liver development; negative regulation of low-density lipoprotein particle clearance; kidney development; cholesterol metabolic process; cellular response to starvation; phospholipid metabolic process; negative regulation of receptor recycling; induction of apoptosis | |
| PCYOX1 | prenylcysteine metabolic process; chloride transport; prenylated protein catabolic process; prenylcysteine catabolic process | |
| PCYT1B | phospholipid biosynthetic process; ovarian follicle development; phosphatidylcholine biosynthetic process; biosynthetic process; spermatogenesis; CDP-choline pathway | |
| PDCD11 | mRNA processing; rRNA processing | |
| PDCD1LG2 | peptidyl-tyrosine dephosphorylation; T cell costimulation; immune response; negative regulation of T cell proliferation; positive regulation of T cell proliferation | |
| PDCD4 | cell aging; negative regulation of transcription, DNA-dependent; negative regulation of cell cycle; negative regulation of JUN kinase activity; apoptotic process | |
| PDCD6 | response to calcium ion; intracellular protein transport; induction of apoptosis by extracellular signals; cellular response to stress; activation of cysteine-type endopeptidase activity involved in apoptotic process | |
| PDE10A | signal transduction; blood coagulation | |
| PDE11A | cGMP catabolic process; blood coagulation; signal transduction; cAMP catabolic process | |
| PDE1A | signal transduction; epidermal growth factor receptor signaling pathway; activation of phospholipase C activity; blood coagulation; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway | |
| PDE1B | cellular response to granulocyte macrophage colony-stimulating factor stimulus; response to amphetamine; nerve growth factor receptor signaling pathway; cGMP catabolic process; serotonin metabolic process; regulation of dopamine metabolic process; cellular response to macrophage colony-stimulating factor stimulus; monocyte differentiation; fibroblast growth factor receptor signaling pathway; visual learning; locomotory behavior; blood coagulation; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; apoptotic process; cAMP catabolic process; regulation of neurotransmitter levels | |
| PDE1C | signal transduction; epidermal growth factor receptor signaling pathway; activation of phospholipase C activity; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway | |
| PDE2A | negative regulation of transcription from RNA polymerase II promoter; cAMP catabolic process; cellular response to granulocyte macrophage colony-stimulating factor stimulus; cellular response to transforming growth factor beta stimulus; cellular response to cGMP; cellular response to mechanical stimulus; calcium ion transmembrane transport; establishment of endothelial barrier; positive regulation of inflammatory response; cGMP catabolic process; positive regulation of vascular permeability; negative regulation of vascular permeability; cellular response to macrophage colony-stimulating factor stimulus; negative regulation of protein import into nucleus, translocation; negative regulation of cAMP biosynthetic process; monocyte differentiation; cGMP-mediated signaling; cAMP-mediated signaling; metabolic process; blood coagulation; signal transduction; protein targeting to mitochondrion; cellular response to drug | |
| PDE3A | regulation of meiosis; response to drug; negative regulation of apoptotic process; negative regulation of vascular permeability; positive regulation of vascular permeability; response to cAMP; positive regulation of oocyte development; cellular response to cGMP; cellular response to transforming growth factor beta stimulus; signal transduction; cGMP-mediated signaling; cAMP-mediated signaling; blood coagulation; lipid metabolic process; cAMP catabolic process; oocyte maturation | |
| PDE3B | negative regulation of lipid catabolic process; negative regulation of insulin secretion; negative regulation of cAMP-mediated signaling; glucose homeostasis; negative regulation of cell adhesion mediated by integrin; cellular response to insulin stimulus; endocrine pancreas development; insulin receptor signaling pathway; blood coagulation; signal transduction; negative regulation of cell adhesion; cAMP catabolic process | |
| PDE4A | cAMP catabolic process; signal transduction; response to drug | |
| PDE4B | cAMP catabolic process; signal transduction | |
| PDE4C | cAMP catabolic process; signal transduction; negative regulation of insulin secretion | |
| PDE4DIP | cellular protein complex assembly | |
| PDE5A | negative regulation of T cell proliferation; vasodilation; response to testosterone stimulus; response to lipopolysaccharide; positive regulation of cardiac muscle hypertrophy; cyclic nucleotide metabolic process; short-term memory; blood coagulation; nervous system development; signal transduction; positive regulation of chronic inflammatory response; regulation of the force of heart contraction; response to hypoxia; positive regulation of oocyte development; relaxation of cardiac muscle; negative regulation of cardiac muscle contraction; cGMP catabolic process; positive regulation of vasoconstriction; positive regulation of MAP kinase activity; positive regulation of apoptotic process | |
| PDE6A | cytosolic calcium ion homeostasis; signal transduction; blood coagulation; visual perception; GMP metabolic process; response to stimulus; retina development in camera-type eye | |
| PDE6C | signal transduction; phototransduction, visible light; visual perception; response to stimulus; retinal cone cell development | |
| PDE7A | cAMP-mediated signaling; signal transduction | |
| PDE7B | signal transduction; synaptic transmission | |
| PDE8B | regulation of transcription, DNA-dependent; cyclic nucleotide metabolic process; negative regulation of insulin secretion | |
| PDE9A | signal transduction; blood coagulation | |
| PDGFB | response to hypoxia; embryonic placenta development; positive regulation of endothelial cell proliferation; monocyte chemotaxis; platelet degranulation; positive regulation of glomerular filtration; protein phosphorylation; transforming growth factor beta receptor signaling pathway; multicellular organismal development; heart development; positive regulation of cyclin-dependent protein kinase activity; positive regulation of smooth muscle cell migration; response to insulin stimulus; response to estradiol stimulus; activation of protein kinase B activity; activation of protein kinase activity; positive regulation of protein autophosphorylation; positive regulation of cell migration; platelet activation; hemopoiesis; peptidyl-tyrosine phosphorylation; peptidyl-serine phosphorylation; cell growth; positive regulation of metanephric mesenchymal cell migration; platelet-derived growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA- | |
| PDGFC | vascular endothelial growth factor receptor signaling pathway; positive regulation of cell division; positive regulation of fibroblast proliferation; platelet-derived growth factor receptor signaling pathway; multicellular organismal development; central nervous system development; positive regulation of DNA replication | |
| PDGFD | multicellular organismal development; regulation of peptidyl-tyrosine phosphorylation; positive regulation of cell division; cellular response to amino acid stimulus | |
| PDGFRA | face morphogenesis; regulation of actin cytoskeleton reorganization; palate development; response to hyperoxia; cardiac myofibril assembly; regulation of chemotaxis; inner ear development; embryonic skeletal system morphogenesis; cell chemotaxis; retina vasculature development in camera-type eye; positive regulation of ERK1 and ERK2 cascade; platelet aggregation; cellular response to amino acid stimulus; metanephric glomerular capillary formation; platelet-derived growth factor receptor-alpha signaling pathway; regulation of mesenchymal stem cell differentiation; response to inorganic substance; adrenal gland development; lung development; extracellular matrix organization; signal transduction involved in regulation of gene expression; peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phospholipase C activity; negative regulation of platelet activation; embryonic digestive tract morphogenesis; response to hormone stimulus; female gonad deve | |
| PDGFRB | in utero embryonic development; cardiac myofibril assembly; positive regulation of mitosis; phosphatidylinositol metabolic process; protein autophosphorylation; platelet-derived growth factor receptor signaling pathway; vascular endothelial growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; positive regulation of smooth muscle cell proliferation; skeletal system morphogenesis; smooth muscle tissue development; regulation of peptidyl-tyrosine phosphorylation; positive regulation of chemotaxis; kidney development; cell chemotaxis; cell migration involved in coronary angiogenesis; retina vasculature development in camera-type eye; positive regulation of ERK1 and ERK2 cascade; smooth muscle cell chemotaxis; metanephric glomerular mesangial cell proliferation involved in metanephros development; metanephric glomerular capillary formation; positive regulation of calcium ion import; positive regulation of reactive oxygen species metabolic process; positive regulation of DNA biosynthet | |
| PDHA1 | pyruvate metabolic process; glycolysis; metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; small molecule metabolic process | |
| PDHA2 | glycolysis | |
| PDHB | regulation of acetyl-CoA biosynthetic process from pyruvate; tricarboxylic acid cycle; glycolysis; pyruvate metabolic process; small molecule metabolic process | |
| PDHX | pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; small molecule metabolic process | |
| PDIA3 | positive regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; protein folding; protein import into nucleus; protein retention in ER lumen; glycerol ether metabolic process; signal transduction; protein N-linked glycosylation via asparagine; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I; post-translational protein modification; cellular protein metabolic process; cell redox homeostasis | |
| PDIA4 | cell redox homeostasis; protein secretion; glycerol ether metabolic process | |
| PDIA5 | oxidation-reduction process; cell redox homeostasis; endoplasmic reticulum unfolded protein response; activation of signaling protein activity involved in unfolded protein response; response to stress; glycerol ether metabolic process; protein folding | |
| PDILT | cell differentiation; cell redox homeostasis; spermatogenesis; multicellular organismal development | |
| PDK1 | regulation of acetyl-CoA biosynthetic process from pyruvate; peptidyl-histidine phosphorylation; small molecule metabolic process; carbohydrate metabolic process; glucose metabolic process; pyruvate metabolic process; protein phosphorylation; cell surface receptor signaling pathway; small GTPase mediated signal transduction | |
| PDK3 | carbohydrate metabolic process; glucose metabolic process; pyruvate metabolic process; protein phosphorylation; regulation of acetyl-CoA biosynthetic process from pyruvate; peptidyl-histidine phosphorylation; small molecule metabolic process | |
| PDK4 | carbohydrate metabolic process; pyruvate metabolic process; protein phosphorylation; regulation of acetyl-CoA biosynthetic process from pyruvate; peptidyl-histidine phosphorylation; small molecule metabolic process; glucose metabolic process | |
| PDLIM3 | actin filament organization; heart development | |
| PDLIM5 | regulation of dendritic spine morphogenesis; regulation of synapse assembly | |
| PDLIM7 | actin cytoskeleton organization; cell differentiation; positive regulation of osteoblast differentiation; receptor-mediated endocytosis; multicellular organismal development; ossification | |
| PDP1 | pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; peptidyl-threonine dephosphorylation; small molecule metabolic process | |
| PDP2 | small molecule metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; protein dephosphorylation; pyruvate metabolic process | |
| PDPK1 | actin cytoskeleton organization; synaptic transmission; protein autophosphorylation; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphorylation; peptidyl-threonine phosphorylation; blood coagulation; platelet activation; negative regulation of transforming growth factor beta receptor signaling pathway; T cell costimulation; activation of protein kinase B activity; cellular response to insulin stimulus; intracellular signal transduction; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; hyperosmotic response; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; focal adhesion assembly; T cell receptor signaling pathway; positive regulation of establishment of protein localization in plasma membrane; regulation of transcription, DNA-dependent; protein phosphorylation; negative regulation of protein kinase activity; epidermal growth factor receptor signaling pathway | |
| PDPN | cell morphogenesis; lung development; lymphangiogenesis; tube morphogenesis; water transport; amino acid transport; positive regulation of platelet activation; folic acid transport; inflammatory response; positive regulation of cellular component movement; lung alveolus development; response to hyperoxia; cell cycle; signal transduction; nervous system development; cell proliferation; regulation of cell shape; embryo development; cell-cell adhesion; positive regulation of cell migration; prostaglandin metabolic process | |
| PDS5B | cell division; regulation of cell proliferation; negative regulation of cell proliferation; cell cycle; mitotic sister chromatid cohesion; mitosis; cell proliferation | |
| PDSS2 | protein heterotetramerization; regulation of body fluid levels; isoprenoid biosynthetic process; ubiquinone biosynthetic process | |
| PDYN | cell death; synaptic transmission; neuropeptide signaling pathway | |
| PDZD11 | - | |
| PDZD2 | cell adhesion | |
| PDZD3 | ion transport; water transport; receptor guanylyl cyclase signaling pathway; response to toxin; cGMP-mediated signaling; negative regulation of cGMP biosynthetic process | |
| PDZD4 | - | |
| PDZD7 | - | |
| PDZD8 | intracellular signal transduction; interspecies interaction between organisms; regulation of cell morphogenesis; cytoskeleton organization | |
| PDZD9 | - | |
| PDZRN3 | neuromuscular junction development; protein ubiquitination | |
| PDZRN4 | - | |
| PEAK1 | - | |
| PEAR1 | recognition of apoptotic cell | |
| PEBP4 | - | |
| PECR | oxidation-reduction process; regulation of apoptotic process; phytol metabolic process; fatty acid biosynthetic process | |
| PEG3 | apoptotic process; viral reproduction | |
| PELI2 | MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 1 signaling pathway; innate immune response; toll-like receptor signaling pathway; positive regulation of MAPK cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 4 signaling pathway; Toll signaling pathway; toll-like receptor 2 signaling pathway; positive regulation of protein phosphorylation | |
| PELI3 | - | |
| PELO | cell cycle; cell proliferation; chromosome organization; cell division | |
| PENK | behavioral fear response; signal transduction; neuropeptide signaling pathway; behavior; sensory perception of pain | |
| PEPD | metabolic process; collagen catabolic process; cellular process; proteolysis; cellular amino acid metabolic process | |
| PER1 | negative regulation of transcription, DNA-dependent; circadian regulation of gene expression; entrainment of circadian clock; response to light stimulus; circadian rhythm; negative regulation of transcription from RNA polymerase II promoter | |
| PER2 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; circadian rhythm | |
| PER3 | negative regulation of transcription from RNA polymerase II promoter; circadian rhythm; regulation of transcription, DNA-dependent | |
| PES1 | mitotic metaphase; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); rRNA processing; nucleolus organization; regulation of cell cycle; ribosomal large subunit biogenesis; cell proliferation | |
| PEX1 | protein transport; protein targeting to peroxisome; peroxisome organization; protein import into peroxisome matrix; microtubule-based peroxisome localization | |
| PEX13 | cerebral cortex cell migration; protein import into peroxisome matrix, docking; protein transport; locomotory behavior; suckling behavior; neuron migration; fatty acid alpha-oxidation; microtubule-based peroxisome localization | |
| PEX14 | protein homooligomerization; protein import into peroxisome matrix; protein transport; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; peroxisome organization | |
| PEX16 | protein targeting to peroxisome; peroxisome organization; peroxisome membrane biogenesis; protein import into peroxisome matrix; ER-dependent peroxisome organization; protein import into peroxisome membrane | |
| PEX19 | protein targeting to peroxisome; peroxisome organization; peroxisome membrane biogenesis; protein import into peroxisome membrane; transmembrane transport; chaperone-mediated protein transport | |
| PEX2 | bile acid biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; neuron migration; peroxisome organization; nervous system development; protein destabilization; regulation of cholesterol biosynthetic process; negative regulation of fibroblast proliferation; negative regulation of epithelial cell proliferation; cholesterol homeostasis | |
| PEX5 | protein targeting to peroxisome; protein transport; protein tetramerization; protein import into peroxisome matrix, translocation | |
| PEX5L | regulated secretory pathway; positive regulation of corticotropin secretion; regulation of cAMP-mediated signaling; protein import into peroxisome matrix | |
| PEX6 | peroxisome organization; ATP catabolic process; protein targeting to peroxisome; protein import into peroxisome matrix, translocation; protein stabilization | |
| PFAS | purine base metabolic process; nucleobase-containing small molecule metabolic process; small molecule metabolic process; purine ribonucleoside monophosphate biosynthetic process; glutamine metabolic process; 'de novo' IMP biosynthetic process; purine nucleotide biosynthetic process | |
| PFKFB1 | response to glucagon stimulus; response to starvation; small molecule metabolic process; carbohydrate phosphorylation; response to glucocorticoid stimulus; response to cAMP; positive regulation of glucokinase activity; response to insulin stimulus; organ regeneration; intracellular protein kinase cascade; energy reserve metabolic process; glycolysis; gluconeogenesis; glucose metabolic process; fructose 2,6-bisphosphate metabolic process; carbohydrate metabolic process | |
| PFKFB2 | small molecule metabolic process; fructose metabolic process; carbohydrate metabolic process; positive regulation of glucokinase activity; positive regulation of insulin secretion; response to glucose stimulus; glycolysis; pyruvate metabolic process; lactate metabolic process; glucose metabolic process; fructose 2,6-bisphosphate metabolic process | |
| PFKFB3 | carbohydrate metabolic process; fructose 2,6-bisphosphate metabolic process; glucose metabolic process; glycolysis; small molecule metabolic process | |
| PFKFB4 | fructose 2,6-bisphosphate metabolic process; small molecule metabolic process; glycolysis; glucose metabolic process; carbohydrate metabolic process | |
| PFKL | carbohydrate metabolic process; fructose 6-phosphate metabolic process; glucose metabolic process; glycolysis; response to glucose stimulus; fructose 1,6-bisphosphate metabolic process; small molecule metabolic process; protein homotetramerization; protein oligomerization; carbohydrate phosphorylation; negative regulation of insulin secretion | |
| PFKM | glucose metabolic process; fructose 6-phosphate metabolic process; protein homotetramerization; protein oligomerization; carbohydrate phosphorylation; muscle cell homeostasis; small molecule metabolic process; glucose homeostasis; positive regulation of insulin secretion; fructose 1,6-bisphosphate metabolic process; glycolysis; carbohydrate metabolic process | |
| PFKP | carbohydrate metabolic process; fructose 6-phosphate metabolic process; glucose metabolic process; glycolysis; fructose 1,6-bisphosphate metabolic process; small molecule metabolic process; protein homotetramerization | |
| PGAM2 | carbohydrate metabolic process; glucose metabolic process; gluconeogenesis; glycolysis; striated muscle contraction; spermatogenesis; response to inorganic substance; small molecule metabolic process; response to mercury ion | |
| PGAP2 | signal transduction in response to DNA damage; protein transport; anti-apoptosis; GPI anchor biosynthetic process | |
| PGBD1 | viral reproduction | |
| PGBD2 | - | |
| PGBD4 | - | |
| PGC | proteolysis; digestion | |
| PGD | pentose-phosphate shunt; carbohydrate metabolic process; pentose-phosphate shunt, oxidative branch; pentose biosynthetic process; small molecule metabolic process; oxidation-reduction process | |
| PGK2 | glycolysis; phosphorylation | |
| PGLYRP3 | detection of bacterium; defense response to Gram-positive bacterium; innate immune response; peptidoglycan catabolic process | |
| PGLYRP4 | detection of bacterium; innate immune response; defense response to Gram-positive bacterium; peptidoglycan catabolic process | |
| PGM2 | glycogen biosynthetic process; glycogen catabolic process; carbohydrate metabolic process; glucose metabolic process; glucose 1-phosphate metabolic process; small molecule metabolic process | |
| PGM2L1 | glucose 1-phosphate metabolic process; carbohydrate metabolic process | |
| PGM3 | carbohydrate metabolic process; cellular protein metabolic process; post-translational protein modification; hemopoiesis; glucose 1-phosphate metabolic process; protein N-linked glycosylation via asparagine; embryo development ending in birth or egg hatching; dolichol-linked oligosaccharide biosynthetic process; UDP-N-acetylglucosamine biosynthetic process; glucosamine metabolic process | |
| PGM5 | trehalose biosynthetic process; galactose catabolic process; cell adhesion; glucose 1-phosphate metabolic process; glycogen biosynthetic process; carbohydrate metabolic process | |
| PGR | negative regulation of gene expression; mammary gland development; tertiary branching involved in mammary gland duct morphogenesis; steroid hormone mediated signaling pathway; regulation of epithelial cell proliferation; progesterone receptor signaling pathway; gene expression; cell-cell signaling; signal transduction; epithelial cell maturation; ovulation from ovarian follicle | |
| PHACTR2 | - | |
| PHACTR3 | - | |
| PHC1 | multicellular organismal development | |
| PHC2 | spermatogenesis; multicellular organismal development | |
| PHEX | biomineral tissue development; cell-cell signaling; proteolysis; protein modification process; skeletal system development | |
| PHF12 | negative regulation of transcription, DNA-dependent | |
| PHF19 | regulation of transcription, DNA-dependent | |
| PHF2 | liver development; negative regulation of chromatin silencing at rDNA; histone H3-K9 demethylation; chromatin modification; protein demethylation; regulation of transcription, DNA-dependent | |
| PHF20 | histone H4-K8 acetylation; regulation of transcription, DNA-dependent; histone H4-K5 acetylation; histone H4-K16 acetylation | |
| PHF20L1 | - | |
| PHF23 | - | |
| PHF24 | - | |
| PHF3 | multicellular organismal development; transcription, DNA-dependent | |
| PHF7 | - | |
| PHGDH | L-serine biosynthetic process; brain development; cellular amino acid biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| PHIP | positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of mitosis; positive regulation of insulin-like growth factor receptor signaling pathway; negative regulation of apoptotic process; regulation of growth; positive regulation of peptidyl-serine phosphorylation; regulation of cell morphogenesis; positive regulation of peptidyl-threonine phosphorylation; insulin receptor signaling pathway; regulation of protein phosphorylation; protein import into nucleus; cytoskeleton organization | |
| PHKA1 | carbohydrate metabolic process; polysaccharide metabolic process; glycogen metabolic process; glycogen catabolic process; small molecule metabolic process; protein autophosphorylation; glucose metabolic process; generation of precursor metabolites and energy | |
| PHKA2 | protein modification process; carbohydrate metabolic process; polysaccharide metabolic process; glycogen catabolic process; glucose metabolic process; generation of precursor metabolites and energy; small molecule metabolic process | |
| PHKB | polysaccharide metabolic process; glycogen metabolic process; glycogen catabolic process; glucose metabolic process; generation of precursor metabolites and energy; carbohydrate metabolic process; small molecule metabolic process | |
| PHKG2 | glycogen metabolic process; carbohydrate metabolic process; glycogen biosynthetic process; glycogen catabolic process; glucose metabolic process; generation of precursor metabolites and energy; protein phosphorylation; small molecule metabolic process; positive regulation of glycogen catabolic process | |
| PHLDA2 | apoptotic process; organ morphogenesis | |
| PHLDB1 | - | |
| PHLDB2 | - | |
| PHLPP2 | - | |
| PHOX2A | noradrenergic neuron differentiation; regulation of transcription, DNA-dependent; somatic motor neuron differentiation; locus ceruleus development; regulation of respiratory gaseous exchange; positive regulation of transcription from RNA polymerase II promoter; sympathetic nervous system development; parasympathetic nervous system development | |
| PHOX2B | cellular response to BMP stimulus; negative regulation of neuron differentiation; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; cell development; neuron migration; cell differentiation in hindbrain; glial cell differentiation; negative regulation of cell proliferation; nervous system development; multicellular organismal development; regulation of transcription, DNA-dependent | |
| PHYH | fatty acid alpha-oxidation; cellular lipid metabolic process; small molecule metabolic process | |
| PHYHD1 | - | |
| PHYHIP | - | |
| PHYHIPL | - | |
| PI15 | - | |
| PI4K2A | phosphatidylinositol biosynthetic process | |
| PI4K2B | - | |
| PI4KA | phosphatidylinositol biosynthetic process; phosphatidylinositol-mediated signaling; synaptic transmission; signal transduction | |
| PI4KB | signal transduction; phosphatidylinositol phosphorylation; phosphatidylinositol-mediated signaling; receptor-mediated endocytosis; phosphatidylinositol biosynthetic process | |
| PIAS4 | negative regulation of NF-kappaB transcription factor activity; Wnt receptor signaling pathway; positive regulation of protein sumoylation; positive regulation of apoptotic process; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| PICALM | protein complex assembly; receptor internalization; regulation of protein localization; hemopoiesis; receptor-mediated endocytosis; positive regulation of transcription, DNA-dependent; negative regulation of receptor-mediated endocytosis; regulation of endocytosis; clathrin coat assembly; dendrite morphogenesis; axonogenesis; vesicle-mediated transport; endosome transport | |
| PICK1 | retrograde vesicle-mediated transport, Golgi to ER; receptor clustering; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; neuronal ion channel clustering; DNA methylation involved in embryo development; DNA methylation involved in gamete generation; protein phosphorylation; monoamine transport; protein targeting; synaptic transmission; ATP catabolic process | |
| PIDD1 | negative regulation of apoptotic process; response to DNA damage stimulus; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; signal transduction | |
| PIEZO2 | ion transport | |
| PIGA | post-translational protein modification; C-terminal protein lipidation; GPI anchor biosynthetic process; biosynthetic process; positive regulation of metabolic process; preassembly of GPI anchor in ER membrane; cellular protein metabolic process | |
| PIGG | GPI anchor biosynthetic process; C-terminal protein lipidation; preassembly of GPI anchor in ER membrane; cellular protein metabolic process; post-translational protein modification | |
| PIGK | protein thiol-disulfide exchange; cellular protein metabolic process; post-translational protein modification; attachment of GPI anchor to protein; proteolysis; C-terminal protein lipidation | |
| PIGM | C-terminal protein lipidation; post-translational protein modification; cellular protein metabolic process; preassembly of GPI anchor in ER membrane | |
| PIGO | preassembly of GPI anchor in ER membrane; post-translational protein modification; cellular protein metabolic process; C-terminal protein lipidation; GPI anchor biosynthetic process | |
| PIGQ | cellular protein metabolic process; post-translational protein modification; preassembly of GPI anchor in ER membrane; C-terminal protein lipidation; carbohydrate metabolic process | |
| PIGR | - | |
| PIGS | C-terminal protein lipidation; cellular protein metabolic process; post-translational protein modification; attachment of GPI anchor to protein | |
| PIGT | neuron differentiation; cellular protein metabolic process; post-translational protein modification; attachment of GPI anchor to protein; neuron apoptosis; C-terminal protein lipidation | |
| PIGV | C-terminal protein lipidation; GPI anchor biosynthetic process; cellular protein metabolic process; post-translational protein modification; preassembly of GPI anchor in ER membrane | |
| PIGW | C-terminal protein lipidation; preassembly of GPI anchor in ER membrane; post-translational protein modification; cellular protein metabolic process | |
| PIH1D1 | box C/D snoRNP assembly | |
| PIH1D2 | - | |
| PIH1D3 | - | |
| PIK3C2A | cell communication; clathrin coat assembly; phosphatidylinositol-mediated signaling; phosphatidylinositol biosynthetic process; exocytosis; endocytosis; epidermal growth factor receptor signaling pathway; insulin receptor signaling pathway; vascular smooth muscle contraction; phosphatidylinositol-3-phosphate biosynthetic process; phosphatidylinositol phosphorylation; platelet-derived growth factor receptor signaling pathway | |
| PIK3C2B | cell communication; protein kinase B signaling cascade; phosphatidylinositol-mediated signaling | |
| PIK3C3 | cytokinesis; endosome organization; cell cycle; insulin receptor signaling pathway; phosphatidylinositol-3-phosphate biosynthetic process; response to leucine; autophagic vacuole assembly; early endosome to late endosome transport; innate immune response; phosphatidylinositol-mediated signaling; regulation of protein secretion | |
| PIK3CA | insulin receptor signaling pathway; positive regulation of peptidyl-serine phosphorylation; T cell costimulation; platelet activation; fibroblast growth factor receptor signaling pathway; angiogenesis; vasculature development; glucose metabolic process; protein kinase B signaling cascade; blood coagulation; epidermal growth factor receptor signaling pathway; signal transduction; anti-apoptosis; protein phosphorylation; insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; nerve growth factor receptor signaling pathway; phosphatidylinositol phosphorylation; phosphatidylinositol-mediated signaling; T cell receptor signaling pathway; leukocyte migration; cardiac muscle contraction; regulation of genetic imprinting; hypomethylation of CpG island; endothelial cell migration; regulation of multicellular organism growth; phosphatidylinositol-3-phosphate biosynthetic process | |
| PIK3CB | activation of MAPK activity; regulation of cell-matrix adhesion; cellular calcium ion homeostasis; endocytosis; blood coagulation; insulin receptor signaling pathway; positive regulation of autophagy; G-protein coupled receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; homophilic cell adhesion; cell adhesion; chemotaxis; regulation of clathrin-mediated endocytosis; platelet aggregation; leukocyte migration; phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; phosphatidylinositol phosphorylation; T cell receptor signaling pathway; phosphatidylinositol 3-kinase cascade; cell migration; platelet activation; phosphatidylinositol-3-phosphate biosynthetic process; embryonic cleavage | |
| PIK3CD | B cell receptor signaling pathway; B cell chemotaxis; phosphatidylinositol-3-phosphate biosynthetic process; T cell activation; B cell activation; mast cell degranulation; innate immune response; phosphatidylinositol phosphorylation; phosphatidylinositol-mediated signaling; T cell receptor signaling pathway; neutrophil extravasation; mast cell differentiation; neutrophil chemotaxis; natural killer cell differentiation; B cell homeostasis; cytokine production; adaptive immune response; mast cell chemotaxis; respiratory burst involved in defense response; protein phosphorylation; chemotaxis; inflammatory response; signal transduction; cell surface receptor signaling pathway; T cell chemotaxis; phosphatidylinositol 3-kinase cascade; natural killer cell activation; cell differentiation; T cell differentiation; natural killer cell chemotaxis | |
| PIK3CG | neutrophil chemotaxis; adaptive immune response; neutrophil extravasation; platelet aggregation; negative regulation of cardiac muscle contraction; phosphatidylinositol phosphorylation; cytokine production; innate immune response; mast cell degranulation; negative regulation of apoptotic process; T cell activation; T cell proliferation; phosphatidylinositol-3-phosphate biosynthetic process; natural killer cell chemotaxis; regulation of cell adhesion mediated by integrin; secretory granule localization; platelet activation; phosphatidylinositol 3-kinase cascade; T cell chemotaxis; blood coagulation; G-protein coupled receptor signaling pathway; inflammatory response; chemotaxis; endocytosis; protein phosphorylation; respiratory burst involved in defense response; positive regulation of acute inflammatory response; dendritic cell chemotaxis | |
| PIK3R1 | regulation of phosphatidylinositol 3-kinase activity; signal transduction; epidermal growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of establishment of protein localization in plasma membrane; growth hormone receptor signaling pathway; leukocyte migration; T cell receptor signaling pathway; phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; insulin-like growth factor receptor signaling pathway; phosphatidylinositol phosphorylation; positive regulation of glucose import; interspecies interaction between organisms; T cell costimulation; platelet activation; phosphatidylinositol 3-kinase cascade; fibroblast growth factor receptor signaling pathway; blood coagulation | |
| PIK3R2 | negative regulation of anti-apoptosis; signal transduction; regulation of small GTPase mediated signal transduction; leukocyte migration; T cell receptor signaling pathway; phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; phosphatidylinositol-3-phosphate biosynthetic process; T cell costimulation; platelet activation; insulin receptor signaling pathway; blood coagulation; small GTPase mediated signal transduction | |
| PIK3R3 | regulation of catalytic activity; regulation of phosphorylation; phosphatidylinositol-3-phosphate biosynthetic process; T cell costimulation; platelet activation; insulin receptor signaling pathway; blood coagulation | |
| PIK3R4 | protein phosphorylation; insulin receptor signaling pathway; innate immune response | |
| PIKFYVE | retrograde transport, endosome to Golgi; cellular protein metabolic process; intracellular signal transduction; protein localization to nucleus; receptor-mediated endocytosis | |
| PIM2 | protein stabilization; anti-apoptosis; cell cycle; protein phosphorylation; G1/S transition of mitotic cell cycle; apoptotic mitochondrial changes; negative regulation of cell proliferation; male meiosis; cell proliferation; response to virus; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription, DNA-dependent; positive regulation of autophagy | |
| PIP4K2B | cell surface receptor signaling pathway | |
| PIP4K2C | - | |
| PIP5K1A | phagocytosis; ruffle assembly; protein targeting to plasma membrane; cell chemotaxis; focal adhesion assembly; activation of Rac GTPase activity; actin cytoskeleton reorganization; keratinocyte differentiation; cell migration; phosphorylation; fibroblast migration; phospholipid biosynthetic process; signal transduction; glycerophospholipid metabolic process | |
| PIP5K1B | phosphorylation | |
| PIP5K1C | actin cytoskeleton organization; neutrophil chemotaxis; synaptic vesicle endocytosis; clathrin-mediated endocytosis; phagocytosis; adherens junction assembly; cell-cell adhesion; synaptic vesicle exocytosis; axon guidance | |
| PIP5KL1 | - | |
| PITHD1 | - | |
| PITPNM1 | lipid metabolic process; protein transport; phototransduction; brain development | |
| PITPNM2 | metabolic process; transport | |
| PITPNM3 | - | |
| PITX1 | cartilage development; skeletal system development; multicellular organismal development; anatomical structure morphogenesis; branchiomeric skeletal muscle development; pituitary gland development; embryonic hindlimb morphogenesis; positive regulation of transcription from RNA polymerase II promoter; myoblast cell fate commitment | |
| PITX2 | camera-type eye development; positive regulation of transcription from RNA polymerase II promoter; somatotropin secreting cell differentiation; prolactin secreting cell differentiation; iris morphogenesis; cell proliferation involved in outflow tract morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cardiac neural crest cell migration involved in outflow tract morphogenesis; regulation of transcription, DNA-dependent; multicellular organismal development; determination of left/right symmetry; hair cell differentiation; deltoid tuberosity development; odontogenesis | |
| PIWIL1 | multicellular organismal development; meiosis; spermatogenesis; gene silencing by RNA; regulation of translation; cell differentiation; piRNA metabolic process; spermatid development | |
| PIWIL2 | germ-line stem cell maintenance; piRNA metabolic process; gene silencing by RNA; meiotic prophase I; multicellular organismal development; spermatogenesis; cell differentiation; oogenesis; DNA methylation involved in gamete generation; RNA 5'-end processing; meiosis; positive regulation of translation | |
| PIWIL3 | cell differentiation; gene silencing by RNA; spermatogenesis; multicellular organismal development; meiosis; regulation of translation | |
| PIWIL4 | meiosis; gene silencing by RNA; piRNA metabolic process; DNA methylation involved in gamete generation; multicellular organismal development; regulation of translation; cell differentiation; spermatogenesis | |
| PJA1 | protein catabolic process | |
| PKD1L1 | left/right axis specification; detection of nodal flow; cell-cell adhesion | |
| PKD1L2 | ion transport; neuropeptide signaling pathway | |
| PKD2L1 | detection of chemical stimulus involved in sensory perception of sour taste; cation transport; sodium ion transmembrane transport; regulation of calcium ion transport via voltage-gated calcium channel activity; cellular response to acidity; potassium ion transmembrane transport | |
| PKD2L2 | ion transport | |
| PKDREJ | neuropeptide signaling pathway; acrosome reaction; ion transport | |
| PKHD1 | kidney development; regulation of centrosome duplication; cell-cell adhesion; cilium assembly; homeostatic process; negative regulation of cellular component movement | |
| PKLR | response to other organism; response to cAMP; small molecule metabolic process; cellular response to insulin stimulus; pyruvate biosynthetic process; response to ATP; response to glucose stimulus; response to lithium ion; carbohydrate metabolic process; response to hypoxia; response to organic cyclic compound; endocrine pancreas development; positive regulation of cellular metabolic process; glucose metabolic process; glycolysis; energy reserve metabolic process; ATP biosynthetic process; response to nutrient; response to heat | |
| PKN1 | activation of JUN kinase activity; epithelial cell migration; signal transduction; protein phosphorylation; chromatin modification; histone H3-T11 phosphorylation; regulation of cell motility; regulation of transcription from RNA polymerase II promoter | |
| PKN2 | positive regulation of mitotic cell cycle; cell division; positive regulation of cell cycle cytokinesis; signal transduction; regulation of transcription, DNA-dependent; protein phosphorylation; apoptotic process; apical junction assembly; cell cycle; epithelial cell migration; regulation of cell motility; cell adhesion | |
| PKN3 | protein phosphorylation; signal transduction; epithelial cell migration | |
| PKNOX1 | positive regulation of transcription from RNA polymerase II promoter; camera-type eye development; erythrocyte differentiation; T cell differentiation; hemopoiesis; regulation of transcription, DNA-dependent; angiogenesis; transcription from RNA polymerase II promoter | |
| PKP1 | multicellular organismal development; signal transduction; cell adhesion; cellular component disassembly involved in apoptosis; apoptotic process | |
| PKP2 | cell-cell adhesion; heart development | |
| PKP3 | cell adhesion | |
| PKP4 | positive regulation of cell cycle cytokinesis; positive regulation of Rho GTPase activity; cell adhesion | |
| PLA1A | phosphatidylserine metabolic process; lipid metabolic process; lipid catabolic process | |
| PLA2G3 | cilium morphogenesis; cell projection organization; lipid catabolic process; phospholipid metabolic process | |
| PLA2G4A | ovulation from ovarian follicle; aging; blood coagulation; response to heat; metabolic process; positive regulation of cell proliferation; luteolysis; platelet activating factor biosynthetic process; icosanoid metabolic process; phospholipid catabolic process; cellular response to antibiotic; response to methylmercury; response to calcium ion; response to glucocorticoid stimulus; positive regulation of inflammatory response; arachidonic acid secretion; decidualization; icosanoid biosynthetic process; surfactant homeostasis; positive regulation of apoptotic process; response to hydrogen peroxide; response to lipopolysaccharide; response to hormone stimulus; response to organic nitrogen; lipid catabolic process; arachidonic acid metabolic process; platelet activation; positive regulation of bone mineralization; positive regulation of vesicle fusion; positive regulation of prostaglandin biosynthetic process; positive regulation of fever generation; response to vitamin D | |
| PLA2G4C | intracellular signal transduction; phospholipid metabolic process; inflammatory response; parturition; metabolic process; lipid catabolic process; arachidonic acid metabolic process; glycerophospholipid catabolic process | |
| PLA2G4F | fatty acid transport; metabolic process; phospholipid catabolic process; lipid catabolic process; arachidonic acid secretion; prostaglandin biosynthetic process; cellular response to antibiotic; cellular response to organic cyclic compound | |
| PLA2G6 | metabolic process; cardiolipin biosynthetic process; lipid catabolic process; cell death | |
| PLA2G7 | lipid catabolic process; positive regulation of monocyte chemotaxis; positive regulation of inflammatory response; low-density lipoprotein particle remodeling; plasma lipoprotein particle oxidation; lipid oxidation | |
| PLA2R1 | regulation of phospholipase A2 activity; receptor-mediated endocytosis; endocytosis; cytokine production; oxidative stress-induced premature senescence; replicative senescence; reactive oxygen species metabolic process; regulation of arachidonic acid secretion; positive regulation of arachidonic acid secretion; positive regulation of DNA damage response, signal transduction by p53 class mediator | |
| PLAT | protein modification process; proteolysis; blood coagulation; plasminogen activation; fibrinolysis; negative regulation of proteolysis | |
| PLAUR | epithelial cell differentiation involved in prostate gland development; mesenchymal cell differentiation; cellular protein metabolic process; post-translational protein modification; skeletal muscle tissue regeneration; regulation of proteolysis; negative regulation of apoptotic process; fibrinolysis; attachment of GPI anchor to protein; negative regulation of gene expression; positive regulation of gene expression; blood coagulation; signal transduction; chemotaxis; cellular component movement; C-terminal protein lipidation | |
| PLB1 | lipid catabolic process; small molecule metabolic process; retinoid metabolic process; steroid metabolic process | |
| PLBD2 | lipid catabolic process | |
| PLCB1 | response to organic nitrogen; positive regulation of acrosome reaction; positive regulation of JNK cascade; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of myoblast differentiation; fat cell differentiation; positive regulation of GTPase activity; response to peptide hormone stimulus; response to monosaccharide stimulus; lipid catabolic process; cerebral cortex development; positive regulation of embryonic development; CD24 biosynthetic process; positive regulation of interleukin-12 production; interleukin-15-mediated signaling pathway; interleukin-12-mediated signaling pathway; intracellular signal transduction; memory; regulation of fertilization; negative regulation of monocyte extravasation; interleukin-1-mediated signaling pathway; activation of meiosis involved in egg activation; G1 phase; positive regulation of developmental growth; G2/M transition of mitotic cell cycle; signal transduction; G-protein coupled acetylcholine | |
| PLCB2 | phospholipid metabolic process; detection of chemical stimulus involved in sensory perception of bitter taste; intracellular signal transduction; lipid catabolic process; synaptic transmission; activation of phospholipase C activity | |
| PLCB3 | post-Golgi vesicle-mediated transport; lipid catabolic process; synaptic transmission; G-protein coupled receptor signaling pathway; intracellular signal transduction | |
| PLCB4 | lipid metabolic process; lipid catabolic process; intracellular signal transduction | |
| PLCD1 | lipid catabolic process; intracellular signal transduction; phospholipid metabolic process | |
| PLCE1 | lipid catabolic process; epidermal growth factor receptor signaling pathway; cell proliferation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; cytoskeleton organization; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; elevation of cytosolic calcium ion concentration; Ras protein signal transduction; heart development; regulation of G-protein coupled receptor protein signaling pathway; calcium-mediated signaling; glomerulus development; regulation of protein kinase activity; regulation of Ras protein signal transduction; inositol phosphate-mediated signaling; regulation of smooth muscle contraction; diacylglycerol biosynthetic process; phospholipid metabolic process; regulation of cell growth; activation of MAPK activity | |
| PLCG2 | response to ATP; calcium-mediated signaling; inositol trisphosphate biosynthetic process; response to lipopolysaccharide; activation of store-operated calcium channel activity; response to magnesium ion; B cell differentiation; platelet activation; Wnt receptor signaling pathway; lipid catabolic process; regulation of gene expression; phospholipid catabolic process; blood coagulation; elevation of cytosolic calcium ion concentration; phosphatidylinositol biosynthetic process; follicular B cell differentiation; negative regulation of programmed cell death; T cell receptor signaling pathway; B cell receptor signaling pathway; release of sequestered calcium ion into cytosol; intracellular signal transduction | |
| PLCH1 | lipid catabolic process; phosphatidylinositol-mediated signaling; intracellular signal transduction | |
| PLCL1 | intracellular signal transduction; behavior; lipid metabolic process | |
| PLCL2 | lipid metabolic process; intracellular signal transduction | |
| PLCXD2 | intracellular signal transduction; lipid catabolic process | |
| PLCXD3 | lipid catabolic process; intracellular signal transduction | |
| PLCZ1 | calcium ion transport; multicellular organismal development; lipid metabolic process; egg activation; metabolic process; lipid catabolic process; intracellular signal transduction | |
| PLD1 | small GTPase mediated signal transduction; Ras protein signal transduction; phospholipid biosynthetic process; phospholipid catabolic process; lipid catabolic process; positive regulation of cell migration; response to peptide hormone stimulus; defense response to Gram-positive bacterium; cell communication; phosphatidic acid biosynthetic process; chemotaxis | |
| PLD2 | positive regulation of phosphatidylinositol 3-kinase cascade; response to hypoxia; G-protein coupled receptor internalization; cytoskeleton organization; cell communication; small GTPase mediated signal transduction; phospholipid catabolic process; positive regulation of receptor-mediated endocytosis; positive regulation of cell adhesion; response to peptide hormone stimulus; positive regulation of mast cell degranulation; response to hydrogen peroxide; neuron projection development; positive regulation of cell migration; lipid catabolic process; response to organic cyclic compound | |
| PLD3 | lipid catabolic process | |
| PLD5 | - | |
| PLEC | apoptotic process; cellular component disassembly involved in apoptosis; hemidesmosome assembly; cell junction assembly | |
| PLEK | thrombin receptor signaling pathway; negative regulation of calcium-mediated signaling; positive regulation of platelet activation; negative regulation of inositol phosphate biosynthetic process; positive regulation of inositol-polyphosphate 5-phosphatase activity; cell projection organization; platelet activation; positive regulation of actin filament depolymerization; inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; cortical actin cytoskeleton organization; ruffle organization; actin cytoskeleton reorganization; positive regulation of actin filament bundle assembly; positive regulation of integrin activation; intracellular signal transduction; negative regulation of G-protein coupled receptor protein signaling pathway; phosphatidylinositol metabolic process; regulation of cell diameter; platelet aggregation; protein kinase C signaling cascade; protein secretion by platelet; blood coagulation; integrin-mediated signaling pathway; vesicle docking involved in exo | |
| PLEKHA4 | - | |
| PLEKHA5 | - | |
| PLEKHB2 | - | |
| PLEKHF2 | - | |
| PLEKHG1 | regulation of Rho protein signal transduction | |
| PLEKHG2 | nerve growth factor receptor signaling pathway; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; small GTPase mediated signal transduction; apoptotic process; regulation of small GTPase mediated signal transduction | |
| PLEKHG3 | regulation of Rho protein signal transduction | |
| PLEKHG4 | regulation of Rho protein signal transduction | |
| PLEKHG4B | regulation of Rho protein signal transduction | |
| PLEKHG5 | apoptotic process; regulation of small GTPase mediated signal transduction; regulation of Rho protein signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade; nerve growth factor receptor signaling pathway; signal transduction; cell death; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals | |
| PLEKHG6 | regulation of Rho protein signal transduction | |
| PLEKHH2 | - | |
| PLEKHH3 | signal transduction | |
| PLEKHN1 | - | |
| PLEKHO2 | - | |
| PLG | fibrinolysis; negative regulation of cell-cell adhesion mediated by cadherin; positive regulation of fibrinolysis; negative regulation of fibrinolysis; tissue remodeling; platelet activation; extracellular matrix disassembly; negative regulation of cell-substrate adhesion; negative regulation of cell proliferation; blood coagulation; proteolysis; platelet degranulation | |
| PLGRKT | positive regulation of plasminogen activation | |
| PLIN1 | lipid metabolic process; lipid catabolic process; triglyceride catabolic process; small molecule metabolic process | |
| PLIN3 | vesicle-mediated transport | |
| PLK1 | mitotic prophase; negative regulation of cyclin-dependent protein kinase activity; protein localization to chromatin; regulation of cell cycle; positive regulation of ubiquitin-protein ligase activity; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; centrosome organization; response to antibiotic; positive regulation of proteolysis; regulation of mitotic anaphase; regulation of protein binding; negative regulation of apoptotic process; polar body extrusion after meiotic divisions; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein destabilization; G2/M transition DNA damage checkpoint; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; G2/M transition of mitotic cell cycle; protein ubiquitination; positive regulation of peptidyl-threonine phosphorylation; cell proliferation; regulation of mitotic cell cycle; | |
| PLOD1 | response to hypoxia; protein modification process; epidermis development; hydroxylysine biosynthetic process; oxidation-reduction process | |
| PLOD2 | response to hypoxia; protein modification process | |
| PLOD3 | in utero embryonic development; endothelial cell morphogenesis; protein localization; neural tube development; collagen fibril organization; cellular response to hormone stimulus; vasodilation; epidermis morphogenesis; lung morphogenesis; basement membrane assembly; protein modification process | |
| PLP1 | cell maturation; long-chain fatty acid biosynthetic process; central nervous system myelination; positive regulation of gene expression; integrin-mediated signaling pathway; synaptic transmission; cell death; axon ensheathment; glial cell differentiation | |
| PLPP2 | sphingolipid biosynthetic process; sphingolipid metabolic process; small molecule metabolic process | |
| PLPP3 | canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration; sphingolipid biosynthetic process; small molecule metabolic process; homotypic cell-cell adhesion; blood vessel development; canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion; canonical Wnt receptor signaling pathway involved in positive regulation of wound healing; positive regulation of peptidyl-tyrosine phosphorylation; protein stabilization; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of Wnt receptor signaling pathway; dephosphorylation; germ cell migration; sphingolipid metabolic process; phospholipid metabolic process; lipid metabolic process; negative regulation of protein phosphorylation; gastrulation with mouth forming second | |
| PLPP4 | phospholipid dephosphorylation | |
| PLPPR2 | - | |
| PLPPR3 | - | |
| PLPPR4 | - | |
| PLPPR5 | - | |
| PLRG1 | nuclear mRNA splicing, via spliceosome; RNA splicing; signal transduction | |
| PLS1 | - | |
| PLS3 | - | |
| PLSCR1 | phosphatidylserine biosynthetic process; apoptotic process; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; regulation of Fc receptor mediated stimulatory signaling pathway; defense response to virus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of innate immune response; negative regulation of viral genome replication; response to interferon-beta; regulation of mast cell activation; platelet activation; phospholipid scrambling; positive regulation of gene expression; acute-phase response | |
| PLTP | lipid metabolic process; transport; lipid transport; vitamin E biosynthetic process; sperm motility | |
| PLVAP | - | |
| PLXDC1 | spinal cord development; angiogenesis | |
| PLXDC2 | - | |
| PLXNA1 | signal transduction; multicellular organismal development; axon guidance; dichotomous subdivision of terminal units involved in salivary gland branching; semaphorin-plexin signaling pathway | |
| PLXNA2 | somitogenesis; multicellular organismal development; axon guidance; neural tube development; cerebellar granule cell precursor tangential migration; regulation of cell migration; centrosome localization; pharyngeal system development; limb bud formation; semaphorin-plexin signaling pathway | |
| PLXNA3 | hippocampus development; axon guidance; multicellular organismal development; signal transduction; pyramidal neuron development; negative regulation of axon extension involved in axon guidance; semaphorin-plexin signaling pathway; positive regulation of cytoskeleton organization; negative chemotaxis | |
| PLXNA4 | semaphorin-plexin signaling pathway; facial nerve morphogenesis; axon guidance; nervous system development; multicellular organismal development; signal transduction; regulation of axon extension involved in axon guidance; neuron projection morphogenesis; sympathetic nervous system development; glossopharyngeal nerve morphogenesis; trigeminal nerve morphogenesis; anterior commissure morphogenesis; chemorepulsion of branchiomotor axon; regulation of negative chemotaxis; postganglionic parasympathetic nervous system development; vagus nerve morphogenesis | |
| PLXNB1 | positive regulation of Rho GTPase activity; axon guidance; negative regulation of osteoblast proliferation; intracellular signal transduction; ossification involved in bone maturation; semaphorin-plexin signaling pathway; trabecula morphogenesis; regulation of cytoskeleton organization; regulation of small GTPase mediated signal transduction; positive regulation of axonogenesis; neuron projection morphogenesis; cell migration; positive regulation of phosphatidylinositol 3-kinase cascade; regulation of cell shape; multicellular organismal development; signal transduction | |
| PLXNB2 | brain development; neural tube closure; regulation of protein phosphorylation; signal transduction; multicellular organismal development; neuroblast proliferation; regulation of cell shape; regulation of Rho GTPase activity; positive regulation of axonogenesis; regulation of small GTPase mediated signal transduction; semaphorin-plexin signaling pathway; regulation of neuron migration | |
| PLXNB3 | axon guidance; multicellular organismal development; signal transduction | |
| PLXNC1 | signal transduction; multicellular organismal development; cell adhesion; axon guidance | |
| PLXND1 | semaphorin-plexin signaling pathway; dichotomous subdivision of terminal units involved in salivary gland branching; regulation of angiogenesis; endothelial cell migration; regulation of cell migration; synapse assembly; axon guidance; multicellular organismal development; signal transduction; patterning of blood vessels; angiogenesis | |
| PMCH | regulation of neuronal synaptic plasticity; signal transduction; positive regulation of circadian sleep/wake cycle, REM sleep; negative regulation of blood pressure; drinking behavior; glucose homeostasis; negative regulation of synaptic transmission, dopaminergic; cell differentiation; response to cold; feeding behavior; behavior; lactation; spermatogenesis; multicellular organismal development; synaptic transmission; neuropeptide signaling pathway; elevation of cytosolic calcium ion concentration; regulation of heart rate | |
| PMEL | melanin biosynthetic process; melanosome organization | |
| PMEPA1 | androgen receptor signaling pathway | |
| PMFBP1 | - | |
| PML | protein targeting; interferon-gamma-mediated signaling pathway; response to cytokine stimulus; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; cell fate commitment; regulation of MHC class I biosynthetic process; negative regulation of transcription, DNA-dependent; negative regulation of mitotic cell cycle; retinoic acid receptor signaling pathway; protein stabilization; maintenance of protein location in nucleus; negative regulation of telomerase activity; interspecies interaction between organisms; branching involved in mammary gland duct morphogenesis; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of extrinsic apoptotic signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; protein complex assembly; positive regulation of defense response to virus by host; regulation of protein phosphorylation; response to hy | |
| PMP2 | - | |
| PMS1 | ATP catabolic process; mismatch repair; reciprocal meiotic recombination | |
| PNCK | - | |
| PNISR | - | |
| PNKD | - | |
| PNLDC1 | - | |
| PNLIPRP1 | response to glucocorticoid stimulus; response to peptide hormone stimulus; pancreas development; lipid metabolic process | |
| PNMA1 | inflammatory response to antigenic stimulus; apoptotic process; spermatogenesis; central nervous system development | |
| PNMA2 | apoptotic process | |
| PNMAL1 | - | |
| PNMT | catecholamine biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| PNN | nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; cell adhesion; RNA splicing | |
| PNPLA3 | triglyceride catabolic process; triglyceride biosynthetic process; lipid catabolic process; metabolic process | |
| PNPLA4 | metabolic process; lipid catabolic process | |
| PNPLA5 | lipid catabolic process; metabolic process | |
| PNPLA6 | cell death; metabolic process; phosphatidylcholine metabolic process; lipid catabolic process | |
| PNPLA7 | lipid metabolic process; metabolic process | |
| PNPLA8 | lipid catabolic process; fatty acid metabolic process; metabolic process | |
| PNPT1 | positive regulation of mitochondrial RNA catabolic process; mitochondrial RNA 5'-end processing; mitochondrial mRNA catabolic process; mitochondrial RNA 3'-end processing; mRNA polyadenylation; mRNA processing; positive regulation of mRNA catabolic process; RNA catabolic process; regulation of cellular senescence; positive regulation of miRNA catabolic process; regulation of cellular respiration; RNA polyadenylation; negative regulation of growth; protein homooligomerization; rRNA import into mitochondrion; RNA import into mitochondrion; protein homotrimerization; mitochondrion morphogenesis; cellular response to interferon-beta; mitotic cell cycle arrest; nuclear polyadenylation-dependent mRNA catabolic process; cellular response to oxidative stress; transport; mRNA catabolic process | |
| PNRC1 | regulation of transcription, DNA-dependent | |
| POC1A | - | |
| PODN | negative regulation of cell migration; negative regulation of cell proliferation | |
| PODNL1 | - | |
| PODXL | positive regulation of cell migration; negative regulation of cell adhesion; epithelial tube formation; glomerular visceral epithelial cell development; leukocyte migration; positive regulation of cell-cell adhesion mediated by integrin; regulation of microvillus assembly; cell migration; negative regulation of cell-cell adhesion | |
| POF1B | - | |
| POFUT1 | O-glycan processing; nervous system development; heart development; embryo development; regulation of transcription, DNA-dependent; fucosylation; protein O-linked fucosylation; angiogenesis; somitogenesis; carbohydrate metabolic process; fucose metabolic process; protein O-linked glycosylation; Notch signaling pathway | |
| POFUT2 | fucose metabolic process; carbohydrate metabolic process | |
| POGK | regulation of transcription, DNA-dependent; multicellular organismal development | |
| POGZ | regulation of transcription, DNA-dependent; cell cycle; mitotic sister chromatid cohesion; cell division; kinetochore assembly | |
| POLA1 | telomere maintenance; M/G1 transition of mitotic cell cycle; telomere maintenance via recombination; mitotic cell cycle; leading strand elongation; lagging strand elongation; DNA replication checkpoint; G1/S transition of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; S phase of mitotic cell cycle; DNA repair; double-strand break repair via nonhomologous end joining; cell proliferation; telomere maintenance via semi-conservative replication; interspecies interaction between organisms; DNA strand elongation involved in DNA replication; DNA-dependent DNA replication initiation; DNA replication, synthesis of RNA primer; DNA replication; nucleobase-containing compound metabolic process; DNA synthesis involved in DNA repair | |
| POLA2 | S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; telomere maintenance via recombination; telomere maintenance; DNA replication; DNA-dependent DNA replication initiation; DNA strand elongation involved in DNA replication; telomere maintenance via semi-conservative replication; G1/S transition of mitotic cell cycle; protein import into nucleus, translocation | |
| POLD1 | regulation of mitotic cell cycle; DNA replication proofreading; DNA replication, removal of RNA primer; telomere maintenance via semi-conservative replication; response to UV; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair; base-excision repair; S phase of mitotic cell cycle; mitotic cell cycle; telomere maintenance via recombination; telomere maintenance; DNA synthesis involved in DNA repair; nucleobase-containing compound metabolic process; base-excision repair, gap-filling; DNA replication; DNA strand elongation involved in DNA replication; DNA repair; transcription-coupled nucleotide-excision repair | |
| POLD2 | mitotic cell cycle; telomere maintenance via semi-conservative replication; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair; base-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; DNA strand elongation involved in DNA replication; DNA replication; telomere maintenance; telomere maintenance via recombination; S phase of mitotic cell cycle | |
| POLD3 | mitotic cell cycle; mismatch repair; S phase of mitotic cell cycle; telomere maintenance via recombination; telomere maintenance; DNA synthesis involved in DNA repair; DNA-dependent DNA replication; DNA strand elongation involved in DNA replication; DNA repair; transcription-coupled nucleotide-excision repair; base-excision repair; nucleotide-excision repair; nucleotide-excision repair, DNA gap filling; telomere maintenance via semi-conservative replication | |
| POLDIP3 | positive regulation of translation | |
| POLE | nucleotide-excision repair, DNA gap filling; telomere maintenance via semi-conservative replication; nucleotide-excision repair; base-excision repair, gap-filling; transcription-coupled nucleotide-excision repair; DNA repair; DNA-dependent DNA replication initiation; DNA replication; nucleobase-containing compound metabolic process; DNA synthesis involved in DNA repair; telomere maintenance; telomere maintenance via recombination; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; in utero embryonic development | |
| POLE2 | telomere maintenance via recombination; telomere maintenance via semi-conservative replication; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; DNA-dependent DNA replication initiation; DNA replication; telomere maintenance; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle | |
| POLG | aging; cell death; metabolic process; mitochondrial DNA replication; DNA-dependent DNA replication; DNA metabolic process; base-excision repair, gap-filling | |
| POLH | DNA synthesis involved in DNA repair; DNA replication; DNA repair; regulation of DNA repair; pyrimidine dimer repair; postreplication repair; response to UV-C | |
| POLK | DNA replication; DNA repair; nucleotide-excision repair, DNA gap filling | |
| POLL | nucleotide-excision repair; metabolic process; somatic hypermutation of immunoglobulin genes; DNA replication; DNA repair | |
| POLN | DNA replication; DNA repair | |
| POLQ | DNA repair; DNA replication | |
| POLR1A | gene expression; rRNA transcription; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; transcription from RNA polymerase I promoter | |
| POLR1B | transcription from RNA polymerase I promoter; gene expression; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; embryo implantation; rRNA transcription; nucleologenesis; embryo development | |
| POLR1C | transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; gene expression; termination of RNA polymerase III transcription; transcription from RNA polymerase III promoter; transcription elongation from RNA polymerase III promoter | |
| POLR1E | rRNA transcription | |
| POLR2A | mRNA capping; transcription-coupled nucleotide-excision repair; protein phosphorylation; RNA splicing; positive regulation of viral transcription; viral reproduction; gene expression; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; nucleotide-excision repair; DNA repair; nuclear mRNA splicing, via spliceosome | |
| POLR2B | DNA repair; transcription-coupled nucleotide-excision repair; nuclear mRNA splicing, via spliceosome; positive regulation of viral transcription; viral reproduction; gene expression; RNA splicing; protein phosphorylation; mRNA capping; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nucleotide-excision repair | |
| POLR2E | transcription from RNA polymerase II promoter; interspecies interaction between organisms; nuclear mRNA splicing, via spliceosome; DNA repair; transcription-coupled nucleotide-excision repair; positive regulation of viral transcription; viral reproduction; gene expression; RNA splicing; termination of RNA polymerase III transcription; nucleotide-excision repair; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; mRNA capping; transcription from RNA polymerase III promoter; transcription elongation from RNA polymerase III promoter; protein phosphorylation | |
| POLR2G | protein phosphorylation; positive regulation of viral transcription; nuclear mRNA splicing, via spliceosome; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; viral reproduction; gene expression; RNA splicing; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; mRNA capping; apoptotic process | |
| POLR3A | transcription elongation from RNA polymerase III promoter; termination of RNA polymerase III transcription; transcription, DNA-dependent; transcription from RNA polymerase III promoter; response to virus; gene expression; positive regulation of interferon-beta production; innate immune response | |
| POLR3B | positive regulation of interferon-beta production; gene expression; positive regulation of innate immune response; response to virus; termination of RNA polymerase III transcription; transcription elongation from RNA polymerase III promoter; transcription from RNA polymerase III promoter | |
| POLRMT | transcription from mitochondrial promoter; transcription initiation from mitochondrial promoter; gene expression | |
| POM121L12 | - | |
| POMGNT1 | protein O-linked glycosylation; protein N-linked glycosylation | |
| POMGNT2 | - | |
| PON2 | response to oxidative stress; aromatic compound catabolic process | |
| POP1 | RNA processing; tRNA catabolic process; tRNA 5'-leader removal | |
| POP4 | rRNA processing; tRNA processing; mRNA cleavage | |
| POSTN | regulation of Notch signaling pathway; extracellular matrix organization; tissue development; cell adhesion; skeletal system development | |
| POT1 | positive regulation of DNA strand elongation; negative regulation of telomerase activity; positive regulation of telomerase activity; positive regulation of helicase activity; DNA duplex unwinding; positive regulation of telomere maintenance via telomerase; negative regulation of telomere maintenance via telomerase; telomere formation via telomerase; telomere capping; telomere maintenance via telomerase; telomere maintenance | |
| POTEA | - | |
| POU1F1 | positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| POU2AF1 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; humoral immune response | |
| POU2F1 | olfactory placode formation; lens induction in camera-type eye; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; gene expression; transcription from RNA polymerase III promoter; regulation of transcription, DNA-dependent | |
| POU2F2 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; humoral immune response | |
| POU3F1 | positive regulation of transcription, DNA-dependent; forebrain development; keratinocyte differentiation; myelination in peripheral nervous system; epidermis development; axon ensheathment; regulation of transcription, DNA-dependent; positive regulation of gene expression | |
| POU3F2 | myelination in peripheral nervous system; regulation of axonogenesis; regulation of cell differentiation; positive regulation of multicellular organism growth; neuron differentiation; neurohypophysis development; hypothalamus cell differentiation; forebrain ventricular zone progenitor cell division; cerebral cortex radially oriented cell migration; astrocyte development; epidermis development; positive regulation of cell proliferation; regulation of transcription, DNA-dependent | |
| POU3F3 | positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; kidney development; regulation of transcription, DNA-dependent; multicellular organismal development; central nervous system development; positive regulation of cell proliferation; positive regulation of gene expression; cerebral cortex radially oriented cell migration; forebrain ventricular zone progenitor cell division; metanephric ascending thin limb development; metanephric macula densa development; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; metanephric thick ascending limb development; metanephric loop of Henle development; negative regulation of apoptotic process; metanephric DCT cell differentiation | |
| POU3F4 | transcription from RNA polymerase II promoter; negative regulation of mesenchymal cell apoptosis; cochlea morphogenesis; inner ear development; forebrain neuron differentiation; sensory perception of sound; regulation of transcription, DNA-dependent | |
| POU4F1 | synapse assembly; negative regulation of transcription from RNA polymerase II promoter; suckling behavior; ventricular compact myocardium morphogenesis; multicellular organismal development; axonogenesis; mesoderm development; cell migration in hindbrain; trigeminal nerve development; central nervous system neuron differentiation; habenula development; positive regulation of apoptotic process; negative regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; neuron fate specification; sensory system development; peripheral nervous system neuron development; regulation of neurogenesis; proprioception involved in equilibrioception; innervation | |
| POU4F2 | axon guidance; positive regulation of cell differentiation; retinal ganglion cell axon guidance; positive regulation of transcription from RNA polymerase II promoter; axon extension involved in development; neuromuscular process controlling balance; retina development in camera-type eye; neuron differentiation; sensory perception of sound; negative regulation of transcription from RNA polymerase II promoter; MAPK cascade; nervous system development; intracellular estrogen receptor signaling pathway | |
| POU4F3 | auditory receptor cell differentiation; neuron apoptosis; neuromuscular process controlling balance; axon extension involved in development; inner ear morphogenesis; retinal ganglion cell axon guidance; vestibulocochlear nerve development; sensory perception of sound; visual perception; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| PPA1 | tRNA aminoacylation for protein translation; phosphate-containing compound metabolic process; metabolic process; gene expression; diphosphate metabolic process | |
| PPA2 | diphosphate metabolic process; gene expression; tRNA aminoacylation for protein translation | |
| PPARA | negative regulation of appetite; intracellular receptor mediated signaling pathway; response to insulin stimulus; wound healing; lipoprotein metabolic process; steroid hormone mediated signaling pathway; cellular lipid metabolic process; small molecule metabolic process; negative regulation of blood pressure; negative regulation of glycolysis; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of fatty acid oxidation; regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter; regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter; positive regulation of fatty acid beta-oxidation; regulation of fatty acid metabolic process; fatty acid transport; negative regulation of sequestering of triglyceride; negative regulation | |
| PPARD | negative regulation of transcription from RNA polymerase II promoter; glucose transport; placenta development; intracellular receptor mediated signaling pathway; cell-substrate adhesion; wound healing; anagen; steroid hormone mediated signaling pathway; keratinocyte proliferation; positive regulation of fat cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; decidualization; cell differentiation; negative regulation of epithelial cell proliferation; keratinocyte migration; adipose tissue development; fatty acid transport; cholesterol metabolic process; glucose metabolic process; generation of precursor metabolites and energy; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; lipid metabolic process; fatty acid beta-oxidation; apoptotic process; embryo implantation; cell proliferation; positive regulation of cell proliferation; axon ensheathment; fatty acid catabolic process; gene | |
| PPARGC1A | positive regulation of fatty acid oxidation; temperature homeostasis; cellular glucose homeostasis; gluconeogenesis; transcription initiation from RNA polymerase II promoter; mRNA processing; protein complex assembly; mitochondrion organization; digestion; RNA splicing; regulation of cell death; response to muscle activity; fatty acid oxidation; respiratory electron transport chain; protein stabilization; androgen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; brown fat cell differentiation; positive regulation of sequence-specific DNA binding transcription factor activity; neuron death; positive regulation of transcription, DNA-dependent; positive regulation of gluconeogenesis; cellular respiration; negative regulation of neuron apoptosis; response to starvation; positive regulation of histone acetylation; cellular response to oxidative stress | |
| PPARGC1B | positive regulation of receptor activity; response to cAMP; response to glucocorticoid stimulus; positive regulation of transcription from RNA polymerase II promoter; intracellular estrogen receptor signaling pathway; regulation of transcription, DNA-dependent | |
| PPAT | glutamine metabolic process; purine base metabolic process; purine nucleotide biosynthetic process; maternal process involved in female pregnancy; nucleobase-containing small molecule metabolic process; protein homotetramerization; small molecule metabolic process; cellular response to insulin stimulus; organ regeneration; purine ribonucleoside monophosphate biosynthetic process; nucleoside metabolic process; purine base biosynthetic process; lactation | |
| PPBP | positive regulation of cell division; defense response to bacterium; platelet degranulation; chemotaxis; immune response; blood coagulation; glucose transport; platelet activation | |
| PPEF1 | detection of stimulus involved in sensory perception; protein dephosphorylation | |
| PPEF2 | protein dephosphorylation; visual perception; negative regulation of peptidyl-threonine phosphorylation; regulation of MAP kinase activity; negative regulation of MAPK cascade; detection of stimulus involved in sensory perception; response to stimulus; regulation of JUN kinase activity | |
| PPFIA1 | signal transduction; cell-matrix adhesion | |
| PPFIA3 | regulation of short-term neuronal synaptic plasticity; neurotransmitter secretion | |
| PPFIBP1 | cell adhesion | |
| PPFIBP2 | DNA integration; cell communication | |
| PPIB | protein peptidyl-prolyl isomerization; protein folding | |
| PPID | protein folding | |
| PPIG | RNA splicing; protein folding | |
| PPIL2 | protein folding; protein polyubiquitination; leukocyte migration; blood coagulation | |
| PPIL3 | RNA splicing; protein folding; nuclear mRNA splicing, via spliceosome | |
| PPIL6 | protein folding | |
| PPIP5K2 | inositol metabolic process | |
| PPL | keratinization | |
| PPM1A | Wnt receptor signaling pathway; negative regulation of SMAD protein complex assembly; dephosphorylation; cell cycle arrest; signal transduction; insulin receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of I-kappaB kinase/NF-kappaB cascade; peptidyl-threonine dephosphorylation; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of Wnt receptor signaling pathway | |
| PPM1B | peptidyl-threonine dephosphorylation; cytokine-mediated signaling pathway; protein dephosphorylation | |
| PPM1D | protein dephosphorylation; negative regulation of cell proliferation; peptidyl-threonine dephosphorylation; response to bacterium; response to radiation; G2/M transition of mitotic cell cycle; cell cycle | |
| PPM1E | negative regulation of protein kinase activity; cellular response to drug; peptidyl-threonine dephosphorylation; positive regulation of stress fiber assembly | |
| PPM1F | positive regulation of growth; intrinsic apoptotic signaling pathway; positive regulation of stress fiber assembly; negative regulation of protein kinase activity; positive regulation of gene expression; positive regulation of epithelial cell migration; positive regulation of cell-substrate adhesion; negative regulation of peptidyl-serine phosphorylation; cellular response to drug; peptidyl-threonine dephosphorylation; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; negative regulation of transcription, DNA-dependent; positive regulation of chemotaxis; positive regulation of focal adhesion assembly | |
| PPM1J | protein dephosphorylation | |
| PPOX | heme biosynthetic process; response to drug; small molecule metabolic process; protoporphyrinogen IX metabolic process; oxidation-reduction process; porphyrin-containing compound metabolic process; porphyrin-containing compound biosynthetic process | |
| PPP1CA | branching morphogenesis of a tube; cell division; small molecule metabolic process; lung development; triglyceride catabolic process; cell cycle; lipid metabolic process; protein dephosphorylation; regulation of glycogen catabolic process; regulation of glycogen biosynthetic process; glycogen metabolic process; carbohydrate metabolic process | |
| PPP1CC | regulation of nucleocytoplasmic transport; cell division; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; carbohydrate metabolic process; glycogen metabolic process; protein dephosphorylation; lipid metabolic process; triglyceride catabolic process; small molecule metabolic process | |
| PPP1R12B | positive regulation of catalytic activity; regulation of muscle contraction; signal transduction | |
| PPP1R13B | apoptotic process; induction of apoptosis; negative regulation of cell cycle | |
| PPP1R13L | negative regulation of transcription from RNA polymerase II promoter; cardiac muscle contraction; multicellular organismal homeostasis; hair cycle; multicellular organism growth; embryonic camera-type eye development; post-embryonic development; apoptotic process; regulation of transcription, DNA-dependent; ventricular cardiac muscle tissue development; cardiac right ventricle morphogenesis | |
| PPP1R15B | regulation of translation; response to oxidative stress; ER overload response; dephosphorylation; response to hydrogen peroxide | |
| PPP1R16A | - | |
| PPP1R16B | regulation of filopodium assembly; signal transduction | |
| PPP1R1B | intracellular signal transduction; signal transduction; transcription, DNA-dependent; response to amphetamine; negative regulation of female receptivity; visual learning | |
| PPP1R21 | - | |
| PPP1R32 | - | |
| PPP1R3A | glycogen metabolic process; carbohydrate metabolic process | |
| PPP1R3B | carbohydrate metabolic process; glycogen metabolic process | |
| PPP1R3D | carbohydrate metabolic process; glycogen metabolic process; regulation of glycogen biosynthetic process; regulation of glycogen catabolic process | |
| PPP1R42 | - | |
| PPP1R8 | RNA splicing; regulation of transcription, DNA-dependent; mRNA processing; RNA catabolic process; cell proliferation; regulation of catalytic activity | |
| PPP1R9A | multicellular organismal development; nervous system development; cell differentiation | |
| PPP2CB | negative regulation of Ras protein signal transduction; protein dephosphorylation; fibroblast growth factor receptor signaling pathway; regulation of gene expression; response to hydrogen peroxide; negative regulation of apoptotic process; proteasomal ubiquitin-dependent protein catabolic process; response to antibiotic | |
| PPP2R1A | gene expression; inactivation of MAPK activity; peptidyl-serine dephosphorylation; regulation of cell differentiation; regulation of apoptotic process; negative regulation of tyrosine phosphorylation of Stat3 protein; regulation of growth; negative regulation of cell growth; regulation of cell adhesion; regulation of Wnt receptor signaling pathway; second-messenger-mediated signaling; mRNA metabolic process; RNA metabolic process; response to organic substance; fibroblast growth factor receptor signaling pathway; RNA splicing; chromosome segregation; induction of apoptosis; ceramide metabolic process; protein dephosphorylation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; G2/M transition of mitotic cell cycle; protein complex assembly; regulation of transcription, DNA-dependent; regulation of DNA replication; mitotic cell cycle | |
| PPP2R1B | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | |
| PPP2R2B | apoptotic process; signal transduction; cell death | |
| PPP2R2C | signal transduction | |
| PPP2R3A | protein dephosphorylation | |
| PPP2R4 | protein folding; positive regulation of apoptotic process; regulation of phosphoprotein phosphatase activity; negative regulation of protein dephosphorylation; positive regulation of protein dephosphorylation; positive regulation of phosphoprotein phosphatase activity; negative regulation of phosphoprotein phosphatase activity; ATP catabolic process | |
| PPP2R5A | negative regulation of lipid kinase activity; negative regulation of establishment of protein localization in plasma membrane; positive regulation of protein dephosphorylation; signal transduction | |
| PPP2R5B | activation of signaling protein activity involved in unfolded protein response; cellular response to growth factor stimulus; positive regulation of cell cycle arrest; negative regulation of G0 to G1 transition; positive regulation of nerve growth factor receptor signaling pathway; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of peptidyl-tyrosine phosphorylation; regulation of protein autophosphorylation; positive regulation of protein complex assembly; endoplasmic reticulum unfolded protein response; positive regulation of neuron projection development; regulation of receptor activity; signal transduction | |
| PPP2R5D | signal transduction; nervous system development | |
| PPP2R5E | signal transduction | |
| PPP3CA | cellular response to drug; cellular response to glucose stimulus; regulation of excitatory postsynaptic membrane potential; regulation of synaptic transmission; skeletal muscle fiber development; negative regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; T cell activation; dephosphorylation; response to stress; calcium ion transport; protein import into nucleus; protein dephosphorylation; response to amphetamine; G1/S transition of mitotic cell cycle | |
| PPP3CB | negative regulation of T cell mediated cytotoxicity; response to amphetamine; protein phosphorylation; protein dephosphorylation; signal transduction; T cell differentiation; learning; heart development; regulation of insulin secretion; axon extension; regulation of synaptic plasticity; muscle cell homeostasis; positive regulation of transcription, DNA-dependent; T cell homeostasis; T cell activation; T cell proliferation; positive regulation of insulin secretion involved in cellular response to glucose stimulus; cellular response to drug; social behavior; response to cytokine stimulus; calcium ion-dependent exocytosis; dephosphorylation; regulation of gene expression; memory | |
| PPP3CC | apoptotic process; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products | |
| PPP4R1 | signal transduction; protein phosphorylation | |
| PPP4R3A | - | |
| PPP4R3B | - | |
| PPP4R4 | - | |
| PPP5C | mitosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; protein dephosphorylation; transcription, DNA-dependent | |
| PPRC1 | regulation of transcription, DNA-dependent | |
| PPT1 | lysosome organization; protein transport; negative regulation of neuron apoptosis; negative regulation of apoptotic process; regulation of phospholipase A2 activity; membrane raft organization; negative regulation of cell growth; protein catabolic process; sphingolipid catabolic process; lipid catabolic process; cellular protein catabolic process; adult locomotory behavior; associative learning; cell death; metabolic process; grooming behavior; visual perception; brain development; nervous system development; positive regulation of receptor-mediated endocytosis; positive regulation of pinocytosis; neuron development; regulation of synapse structure and activity; response to stimulus; cofactor transport; cofactor metabolic process; protein depalmitoylation; DNA fragmentation involved in apoptotic nuclear change; neurotransmitter secretion; lysosomal lumen acidification; pinocytosis; receptor-mediated endocytosis; protein modification process | |
| PPTC7 | - | |
| PQBP1 | regulation of transcription, DNA-dependent | |
| PRAMEF12 | - | |
| PRC1 | cytokinesis; cell cycle; mitotic spindle elongation | |
| PRDM1 | embryonic placenta development; positive regulation of B cell differentiation; negative regulation of transcription from RNA polymerase II promoter; cell fate commitment; negative regulation of lipopolysaccharide-mediated signaling pathway; maternal placenta development; germ cell development; positive regulation of gene expression; negative regulation of B cell proliferation | |
| PRDM10 | regulation of transcription, DNA-dependent | |
| PRDM13 | regulation of transcription, DNA-dependent | |
| PRDM14 | cell morphogenesis; cell fate specification; regulation of transcription, DNA-dependent; fertilization; homeostasis of number of cells within a tissue; germ cell development | |
| PRDM15 | regulation of transcription, DNA-dependent | |
| PRDM16 | positive regulation of transcription, DNA-dependent; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of granulocyte differentiation; neurogenesis; negative regulation of transcription from RNA polymerase II promoter; palate development; regulation of cellular respiration; brown fat cell differentiation; somatic stem cell maintenance; negative regulation of transcription, DNA-dependent; tongue development; white fat cell differentiation | |
| PRDM2 | response to estradiol stimulus; regulation of transcription, DNA-dependent | |
| PRDM4 | regulation of transcription, DNA-dependent; cellular response to growth factor stimulus; nerve growth factor receptor signaling pathway; negative regulation of cell cycle; cellular response to nutrient; negative regulation of cell growth; cell proliferation; transcription from RNA polymerase II promoter; signal transduction | |
| PRDM8 | regulation of transcription, DNA-dependent | |
| PRDX2 | response to lipopolysaccharide; removal of superoxide radicals; regulation of hydrogen peroxide metabolic process; positive regulation of blood coagulation; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of NF-kappaB transcription factor activity; response to oxidative stress; anti-apoptosis; respiratory burst involved in inflammatory response; activation of MAPK activity; cellular response to oxidative stress; T cell proliferation; hydrogen peroxide catabolic process; regulation of apoptotic process; negative regulation of T cell differentiation; thymus development; homeostasis of number of cells; negative regulation of reactive oxygen species metabolic process | |
| PREB | activation of signaling protein activity involved in unfolded protein response; protein N-linked glycosylation via asparagine; endoplasmic reticulum unfolded protein response; vesicle-mediated transport; post-translational protein modification; cellular protein metabolic process; COPII vesicle coating; cellular membrane organization; protein transport; ER to Golgi vesicle-mediated transport; regulation of transcription, DNA-dependent | |
| PRELP | skeletal system development; cell aging | |
| PREPL | proteolysis | |
| PREX1 | regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; neutrophil activation; regulation of Rho protein signal transduction; positive regulation of Rho GTPase activity; actin filament polymerization; induction of apoptosis by extracellular signals; superoxide metabolic process; small GTPase mediated signal transduction; apoptotic process | |
| PREX2 | positive regulation of Rac GTPase activity; intracellular signal transduction; regulation of Rho protein signal transduction; G-protein coupled receptor signaling pathway | |
| PRG3 | positive regulation of interleukin-8 biosynthetic process; superoxide anion generation; histamine biosynthetic process; neutrophil activation; basophil activation; immune response; negative regulation of translation; leukotriene biosynthetic process | |
| PRG4 | immune response; cell proliferation | |
| PRICKLE1 | negative regulation of cardiac muscle cell myoblast differentiation; neural tube closure; protein import into nucleus; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of transcription, DNA-dependent; negative regulation of canonical Wnt receptor signaling pathway | |
| PRICKLE2 | neuron projection development; establishment or maintenance of epithelial cell apical/basal polarity | |
| PRICKLE3 | - | |
| PRICKLE4 | - | |
| PRIMA1 | establishment of localization in cell; neurotransmitter catabolic process | |
| PRKAA1 | signal transduction; cellular response to glucose starvation; histone-serine phosphorylation; negative regulation of TOR signaling cascade; cellular response to nutrient levels; chromatin modification; Wnt receptor signaling pathway; positive regulation of autophagy; lipid biosynthetic process; insulin receptor signaling pathway; positive regulation of anti-apoptosis; cell cycle arrest; response to stress; fatty acid biosynthetic process; positive regulation of cholesterol biosynthetic process; activation of MAPK activity; response to hypoxia; regulation of transcription, DNA-dependent; protein phosphorylation; regulation of circadian rhythm; glucose homeostasis; rhythmic process; negative regulation of lipid catabolic process; fatty acid homeostasis; regulation of energy homeostasis; regulation of fatty acid oxidation; negative regulation of glucosylceramide biosynthetic process; positive regulation of glycolysis; negative regulation of apoptotic process | |
| PRKAA2 | regulation of fatty acid oxidation; cellular response to glucose starvation; regulation of fatty acid biosynthetic process; glucose homeostasis; regulation of circadian rhythm; negative regulation of apoptotic process; cellular lipid metabolic process; small molecule metabolic process; positive regulation of glycolysis; regulation of energy homeostasis; rhythmic process; protein heterooligomerization; fatty acid homeostasis; cellular response to organic nitrogen; negative regulation of TOR signaling cascade; carnitine shuttle; response to stress; cell cycle arrest; histone-serine phosphorylation; cholesterol biosynthetic process; protein phosphorylation; regulation of transcription, DNA-dependent; energy reserve metabolic process; signal transduction; insulin receptor signaling pathway; lipid biosynthetic process; positive regulation of autophagy; response to activity; Wnt receptor signaling pathway; chromatin modification; regulation of lipid metabolic process; response to caffeine; cellular response to nutr | |
| PRKACB | transmembrane transport; carbohydrate metabolic process; glucose metabolic process; energy reserve metabolic process; regulation of insulin secretion; cellular response to glucagon stimulus; nerve growth factor receptor signaling pathway; small molecule metabolic process; activation of protein kinase A activity; triglyceride catabolic process; fibroblast growth factor receptor signaling pathway; blood coagulation; synaptic transmission; intracellular protein kinase cascade; activation of phospholipase C activity; G-protein signaling, coupled to cAMP nucleotide second messenger; epidermal growth factor receptor signaling pathway; signal transduction; water transport; gluconeogenesis; lipid metabolic process; protein phosphorylation | |
| PRKACG | nerve growth factor receptor signaling pathway; intracellular protein kinase cascade; activation of phospholipase C activity; spermatogenesis; blood coagulation; carbohydrate metabolic process; fibroblast growth factor receptor signaling pathway; male gonad development; triglyceride catabolic process; activation of protein kinase A activity; small molecule metabolic process; regulation of insulin secretion; transmembrane transport; cellular response to glucagon stimulus; epidermal growth factor receptor signaling pathway; signal transduction; water transport; lipid metabolic process; energy reserve metabolic process; gluconeogenesis; glucose metabolic process | |
| PRKAG1 | regulation of fatty acid oxidation; protein heterooligomerization; regulation of catalytic activity; positive regulation of protein kinase activity; regulation of glycolysis; insulin receptor signaling pathway; spermatogenesis; signal transduction; cell cycle arrest; fatty acid biosynthetic process; protein phosphorylation | |
| PRKAG2 | sterol biosynthetic process; regulation of fatty acid oxidation; positive regulation of peptidyl-threonine phosphorylation; insulin receptor signaling pathway; intracellular protein kinase cascade; cell cycle arrest; carnitine shuttle; ATP biosynthetic process; negative regulation of protein kinase activity; energy reserve metabolic process; regulation of glycolysis; glycogen metabolic process; regulation of fatty acid metabolic process; regulation of fatty acid biosynthetic process; cellular lipid metabolic process; small molecule metabolic process; positive regulation of protein kinase activity; regulation of glucose import; regulation of catalytic activity | |
| PRKAR1B | regulation of protein phosphorylation; cellular response to glucagon stimulus; transmembrane transport; regulation of insulin secretion; nerve growth factor receptor signaling pathway; small molecule metabolic process; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; blood coagulation; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; water transport; protein phosphorylation; energy reserve metabolic process | |
| PRKAR2B | G2/M transition of mitotic cell cycle; cellular response to glucagon stimulus; transmembrane transport; regulation of insulin secretion; regulation of catalytic activity; nerve growth factor receptor signaling pathway; regulation of protein kinase activity; small molecule metabolic process; intracellular signal transduction; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; mitotic cell cycle; energy reserve metabolic process; fatty acid metabolic process; water transport; signal transduction; epidermal growth factor receptor signaling pathway; activation of phospholipase C activity; blood coagulation; learning | |
| PRKCA | energy reserve metabolic process; fibroblast growth factor receptor signaling pathway; positive regulation of lipopolysaccharide-mediated signaling pathway; platelet activation; mRNA metabolic process; RNA metabolic process; positive regulation of cardiac muscle hypertrophy; positive regulation of endothelial cell migration; gene expression; induction of apoptosis by extracellular signals; negative regulation of glial cell apoptosis; blood coagulation; synaptic transmission; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; apoptotic process; protein phosphorylation; positive regulation of endothelial cell proliferation; histone H3-T6 phosphorylation; positive regulation of dense core granule biogenesis; regulation of platelet aggregation; response to interleukin-1; positive regulation of ERK1 and ERK2 cascade; regulation of insulin secretion; nerve growth factor receptor signaling pathway; positive regulation of mitotic cell cycle; positive regul | |
| PRKCB | apoptotic process; signal transduction; protein phosphorylation; regulation of transcription from RNA polymerase II promoter; synaptic transmission; blood coagulation; positive regulation of NF-kappaB transcription factor activity; positive regulation of B cell receptor signaling pathway; B cell receptor signaling pathway; negative regulation of insulin receptor signaling pathway; positive regulation of angiogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; lipoprotein transport; B cell activation; intracellular signal transduction; histone H3-T6 phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; platelet activation; chromatin modification; negative regulation of glucose transport | |
| PRKCD | cell cycle; signal transduction; cellular component disassembly involved in apoptosis; apoptotic process; RNA metabolic process; interleukin-10 production; negative regulation of protein binding; negative regulation of actin filament polymerization; platelet activation; termination of signal transduction; cytokine-mediated signaling pathway; peptidyl-threonine phosphorylation; mRNA metabolic process; interleukin-12 production; positive regulation of superoxide anion generation; immunoglobulin mediated immune response; regulation of receptor activity; gene expression; fibroblast growth factor receptor signaling pathway; blood coagulation; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; positive regulation of response to DNA damage stimulus; negative regulation of glial cell apoptosis; positive regulation of protein dephosphorylation; intracellular signal transduction; B cell proliferation; neutrophil activation; positive regulation of catalytic activity; negative reg | |
| PRKCE | nerve growth factor receptor signaling pathway; blood coagulation; lipopolysaccharide-mediated signaling pathway; positive regulation of actin filament polymerization; platelet activation; regulation of lipid metabolic process; positive regulation of cell-substrate adhesion; positive regulation of fibroblast migration; positive regulation of epithelial cell migration; fibroblast growth factor receptor signaling pathway; positive regulation of cell cycle cytokinesis; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; cell adhesion; cell cycle; induction of apoptosis; protein phosphorylation; macrophage activation involved in immune response; positive regulation of synaptic transmission, GABAergic; positive regulation of wound healing; cellular response to hypoxia; cellular response to ethanol; positive regulation of mucus secretion; regulation of insulin secretion involved in cellular response to glucose stimulus; cell division; release of sequester | |
| PRKCG | negative regulation of protein catabolic process; protein phosphorylation; innervation; response to pain; nerve growth factor receptor signaling pathway; negative regulation of neuron apoptosis; response to morphine; intracellular signal transduction; positive regulation of mismatch repair; negative regulation of protein ubiquitination; platelet activation; phosphorylation; cell death; chemosensory behavior; learning or memory; blood coagulation; synaptic transmission; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; fibroblast growth factor receptor signaling pathway | |
| PRKCH | intracellular signal transduction; positive regulation of keratinocyte differentiation; positive regulation of B cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; positive regulation of glial cell proliferation; regulation of tight junction assembly; negative regulation of glial cell apoptosis; platelet activation; cell differentiation; positive regulation of macrophage derived foam cell differentiation; blood coagulation; signal transduction; protein phosphorylation | |
| PRKCI | actin filament organization; protein targeting to membrane; cytoskeleton organization; positive regulation of neuron projection development; protein phosphorylation; cellular membrane organization; vesicle-mediated transport; cellular response to insulin stimulus; cell junction assembly; negative regulation of glial cell apoptosis; establishment of apical/basal cell polarity; intracellular signal transduction; eye photoreceptor cell development; response to peptide hormone stimulus; negative regulation of neuron apoptosis; cell-cell junction organization; anti-apoptosis; establishment or maintenance of epithelial cell apical/basal polarity; positive regulation of endothelial cell apoptosis; positive regulation of establishment of protein localization in plasma membrane; tight junction assembly; response to interleukin-1; positive regulation of glial cell proliferation; positive regulation of NF-kappaB transcription factor activity; Golgi vesicle budding; nerve growth factor receptor signaling pathway; secreti | |
| PRKCQ | positive regulation of T cell proliferation; intracellular signal transduction; response to insulin stimulus; tissue regeneration; positive regulation of interleukin-4 production; response to heat; positive regulation of interleukin-17 production; neuron differentiation; platelet activation; regulation of vasoconstriction; response to organic cyclic compound; regulation of G2/M transition of mitotic cell cycle; response to glucose stimulus; positive regulation of NF-kappaB import into nucleus; positive regulation of interleukin-2 biosynthetic process; respiratory burst; negative regulation of insulin receptor signaling pathway; positive regulation of protein secretion; T cell receptor signaling pathway; positive regulation of T cell activation; positive regulation of NF-kappaB transcription factor activity; positive regulation of filopodium assembly; response to hypoxia; positive regulation of stress fiber assembly; negative regulation of T cell apoptosis; regulation of platelet aggregation; positive regulati | |
| PRKCZ | peptidyl-serine phosphorylation; inflammatory response; positive regulation of interleukin-10 secretion; positive regulation of interleukin-13 secretion; positive regulation of interleukin-5 secretion; positive regulation of T-helper 2 cell cytokine production; positive regulation of excitatory postsynaptic membrane potential; microtubule cytoskeleton organization; protein phosphorylation; anti-apoptosis; signal transduction; blood coagulation; positive regulation of ERK1 and ERK2 cascade; establishment of cell polarity; platelet activation; negative regulation of protein complex assembly; positive regulation of interleukin-4 production; intracellular signal transduction; positive regulation of T-helper 2 cell differentiation; negative regulation of insulin receptor signaling pathway; positive regulation of insulin receptor signaling pathway; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of NF-kappaB transcription factor activity; long-term synaptic potentiation | |
| PRKD1 | apoptotic process; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; vascular endothelial growth factor receptor signaling pathway; Golgi vesicle transport; positive regulation of NF-kappaB transcription factor activity; negative regulation of cell death; positive regulation of endothelial cell proliferation; sphingolipid metabolic process; cell differentiation; inflammatory response; Golgi organization; signal transduction; integrin-mediated signaling pathway; intracellular protein kinase cascade; regulation of integrin-mediated signaling pathway; nervous system development; cell proliferation; positive regulation of angiogenesis; sphingolipid biosynthetic process; positive regulation of CREB transcription factor activity; cellular response to oxidative stress; endothelial cell chemotaxis; cellular response to vascular endothelial growth factor stimulus; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of endothelial cell migration | |
| PRKD2 | positive regulation of T cell receptor signaling pathway; positive regulation of endothelial cell migration; cell death; intracellular protein kinase cascade; positive regulation of DNA biosynthetic process; protein phosphorylation; positive regulation of endothelial cell proliferation; positive regulation of ERK1 and ERK2 cascade; endothelial tube morphogenesis; positive regulation of NF-kappaB transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; peptidyl-serine phosphorylation; T cell receptor signaling pathway; vascular endothelial growth factor receptor signaling pathway; protein autophosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell adhesion; positive regulation of angiogenesis; endothelial cell chemotaxis; positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of blood vessel endothelial cell migration; cellular response to vascular endoth | |
| PRKD3 | protein phosphorylation; intracellular signal transduction; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway | |
| PRKG1 | regulation of GTPase activity; actin cytoskeleton organization; blood coagulation; signal transduction; protein phosphorylation; negative regulation of platelet aggregation | |
| PRKG2 | regulation of nitric-oxide synthase activity; nitric oxide metabolic process; small molecule metabolic process; blood coagulation; signal transduction; protein phosphorylation | |
| PRKRIR | response to stress; signal transduction; negative regulation of cell proliferation | |
| PRLH | G-protein coupled receptor signaling pathway; feeding behavior; reduction of food intake in response to dietary excess | |
| PRLHR | hormone metabolic process; feeding behavior; female pregnancy; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway | |
| PRLR | cell surface receptor signaling pathway; lactation; regulation of cell adhesion; regulation of epithelial cell differentiation; T cell activation; activation of JAK2 kinase activity; JAK-STAT cascade involved in growth hormone signaling pathway; mammary gland epithelial cell differentiation; prostate gland growth; mammary gland alveolus development; steroid biosynthetic process; anti-apoptosis; activation of transmembrane receptor protein tyrosine kinase activity; embryo implantation | |
| PRMT1 | cell surface receptor signaling pathway; protein methylation; in utero embryonic development; histone methylation; peptidyl-arginine methylation; neuron projection development; histone H4-R3 methylation; negative regulation of megakaryocyte differentiation | |
| PRMT2 | negative regulation of transcription, DNA-dependent; peptidyl-arginine N-methylation; histone arginine methylation; developmental cell growth; regulation of androgen receptor signaling pathway; protein methylation; induction of apoptosis; signal transduction; histone methylation; negative regulation of NF-kappaB transcription factor activity; positive regulation of transcription, DNA-dependent; negative regulation of G1/S transition of mitotic cell cycle | |
| PRMT3 | peptidyl-arginine N-methylation | |
| PRMT5 | spliceosomal snRNP assembly; gene expression; regulation of transcription, DNA-dependent; cell proliferation; RNA metabolic process; chromatin modification; peptidyl-arginine methylation; peptidyl-arginine methylation, to symmetrical-dimethyl arginine; ncRNA metabolic process; peptidyl-arginine N-methylation; regulation of mitosis; histone H4-R3 methylation | |
| PRMT6 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; base-excision repair; chromatin modification; histone methylation; histone H3-R2 methylation; histone H4-R3 methylation; interspecies interaction between organisms; negative regulation of transcription, DNA-dependent | |
| PRNP | metabolic process; negative regulation of calcineurin-NFAT signaling cascade; protein homooligomerization; negative regulation of T cell receptor signaling pathway; response to copper ion; response to cadmium ion; negative regulation of activated T cell proliferation; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of interleukin-2 production; negative regulation of interleukin-17 production; negative regulation of interferon-gamma production; axon guidance; cell cycle arrest; cell cycle; response to oxidative stress; anti-apoptosis; cellular copper ion homeostasis; negative regulation of protein phosphorylation | |
| PROC | peptidyl-glutamic acid carboxylation; proteolysis; blood coagulation; leukocyte migration; cellular protein metabolic process; post-translational protein modification; negative regulation of apoptotic process; negative regulation of blood coagulation | |
| PROCA1 | lipid catabolic process | |
| PRODH2 | proline catabolic process; glutamate biosynthetic process | |
| PROKR1 | anti-apoptosis | |
| PROKR2 | - | |
| PROM2 | - | |
| PROP1 | canonical Wnt receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; blood vessel development; central nervous system development; organ morphogenesis; dorsal/ventral pattern formation; cell migration; hypothalamus cell differentiation; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; gland development; somatotropin secreting cell differentiation; hypophysis morphogenesis | |
| PROSC | - | |
| PROSER1 | - | |
| PROSER2 | - | |
| PROX1 | endocardium formation; positive regulation of sarcomere organization; ventricular septum morphogenesis; aorta smooth muscle tissue morphogenesis; positive regulation of heart growth; lymphatic endothelial cell differentiation; regulation of transcription involved in lymphatic endothelial cell fate commitment; lens fiber cell morphogenesis; hepatocyte differentiation; negative regulation of bile acid biosynthetic process; hepatocyte proliferation; neuronal stem cell maintenance; positive regulation of neural precursor cell proliferation; positive regulation of forebrain neuron differentiation; positive regulation of G1/S transition checkpoint; multicellular organismal development; embryonic retina morphogenesis in camera-type eye; otic placode formation; pancreas development; negative regulation of transcription from RNA polymerase II promoter; cell fate determination; kidney development; liver development; positive regulation of endothelial cell proliferation; lymphangiogenesis; lens development in camera-typ | |
| PROZ | proteolysis; cellular protein metabolic process; post-translational protein modification; peptidyl-glutamic acid carboxylation; blood coagulation | |
| PRPF19 | DNA repair; RNA splicing; lipid biosynthetic process; negative regulation of neuron differentiation; positive regulation of astrocyte differentiation; inner cell mass cell proliferation; nuclear mRNA splicing, via spliceosome; spliceosome assembly; protein polyubiquitination | |
| PRPF3 | nuclear mRNA splicing, via spliceosome; RNA splicing; mRNA processing; RNA splicing, via transesterification reactions | |
| PRPF31 | RNA splicing; assembly of spliceosomal tri-snRNP; nuclear mRNA splicing, via spliceosome | |
| PRPF38B | mRNA processing; RNA splicing | |
| PRPF40B | mRNA processing; RNA splicing | |
| PRPF4B | RNA splicing; nuclear mRNA splicing, via spliceosome; protein phosphorylation | |
| PRPF8 | RNA splicing; mRNA processing; nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; gene expression | |
| PRPH | intermediate filament cytoskeleton organization | |
| PRPS1 | 5-phosphoribose 1-diphosphate biosynthetic process; hypoxanthine biosynthetic process; carbohydrate metabolic process; purine base metabolic process; purine nucleotide biosynthetic process; nervous system development; nucleoside metabolic process; ribonucleoside monophosphate biosynthetic process; urate biosynthetic process; small molecule metabolic process; cellular biosynthetic process; pyrimidine nucleotide biosynthetic process | |
| PRPSAP1 | negative regulation of catalytic activity; nucleotide biosynthetic process; nucleobase-containing compound metabolic process | |
| PRPSAP2 | nucleobase-containing compound metabolic process; nucleotide biosynthetic process; negative regulation of catalytic activity | |
| PRR11 | - | |
| PRR14 | - | |
| PRR16 | - | |
| PRR19 | - | |
| PRR21 | - | |
| PRR5 | cell cycle | |
| PRR5L | - | |
| PRRG1 | - | |
| PRRG2 | - | |
| PRRT2 | response to biotic stimulus | |
| PRRT3 | - | |
| PRRX1 | multicellular organismal development | |
| PRRX2 | cartilage development; artery morphogenesis; multicellular organismal development; embryonic cranial skeleton morphogenesis; positive regulation of smoothened signaling pathway; middle ear morphogenesis; inner ear morphogenesis; embryonic limb morphogenesis; regulation of transcription, DNA-dependent; positive regulation of mesenchymal cell proliferation | |
| PRSS12 | proteolysis; zymogen activation | |
| PRSS16 | proteolysis; protein catabolic process | |
| PRSS22 | proteolysis | |
| PRSS23 | proteolysis | |
| PRSS35 | - | |
| PRSS36 | proteolysis | |
| PRSS53 | proteolysis | |
| PRSS55 | proteolysis | |
| PRSS57 | proteolysis | |
| PRSS58 | proteolysis | |
| PRUNE2 | G1 phase; induction of apoptosis; apoptotic process | |
| PSAP | blood coagulation; small molecule metabolic process; positive regulation of catalytic activity; platelet activation; lipid transport; sphingolipid metabolic process; lipid metabolic process; platelet degranulation; glycosphingolipid metabolic process | |
| PSAT1 | L-serine biosynthetic process; pyridoxine biosynthetic process; cellular amino acid biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| PSD | signal transduction; neuron differentiation; regulation of ARF protein signal transduction | |
| PSD3 | regulation of ARF protein signal transduction | |
| PSD4 | regulation of ARF protein signal transduction | |
| PSEN1 | negative regulation of ubiquitin-protein ligase activity; hemopoietic progenitor cell differentiation; T cell activation involved in immune response; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; calcium ion transmembrane transport; regulation of resting membrane potential; regulation of synaptic transmission, glutamatergic; smooth endoplasmic reticulum calcium ion homeostasis; neuron migration; T cell receptor signaling pathway; positive regulation of coagulation; heart looping; positive regulation of protein phosphorylation; negative regulation of protein phosphorylation; positive regulation of receptor recycling; somitogenesis; cell fate specification; blood vessel development; activation of MAPKK activity; negative regulation of transcription from RNA polymerase II promoter; autophagic vacuole assembly; negative regulation of protein kinase activity; endoplasmic reticulum calcium ion homeostasis; synaptic vesicle targeting; cell-cell adhesion; pro | |
| PSEN2 | memory; Notch receptor processing; Notch signaling pathway; negative regulation of epidermal growth factor-activated receptor activity; anti-apoptosis; apoptotic process; calcium ion transport; membrane protein ectodomain proteolysis; proteolysis; myeloid leukocyte differentiation; T cell activation involved in immune response; hemopoietic progenitor cell differentiation; hair follicle development; negative regulation of protein phosphorylation; embryo development; positive regulation of receptor recycling; somitogenesis; cell fate specification; response to hypoxia; negative regulation of transcription from RNA polymerase II promoter; dorsal/ventral neural tube patterning; regulation of synaptic plasticity; nerve growth factor receptor signaling pathway; skin morphogenesis; positive regulation of catalytic activity; positive regulation of apoptotic process; amyloid precursor protein catabolic process; anagen; locomotion; intracellular signal transduction; positive regulation of proteasomal ubiquitin-dependen | |
| PSIP1 | interspecies interaction between organisms; positive regulation of transcription from RNA polymerase II promoter; initiation of viral infection; provirus integration; nuclear mRNA 5'-splice site recognition; regulation of transcription, DNA-dependent; viral reproduction; response to heat; response to oxidative stress | |
| PSKH1 | protein phosphorylation | |
| PSKH2 | - | |
| PSMA8 | protein polyubiquitination; regulation of cellular amino acid metabolic process; ubiquitin-dependent protein catabolic process; apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; mRNA metabolic process; S phase of mitotic cell cycle; antigen processing and presentation of peptide antigen via MHC class I; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of apoptotic process; mitotic cell cycle; cell cycle checkpoint; proteolysis involved in cellular protein catabolic process; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; small molecule metabolic process; positive regulation of u | |
| PSMB1 | S phase of mitotic cell cycle; RNA metabolic process; viral reproduction; gene expression; small molecule metabolic process; cell cycle checkpoint; G1/S transition of mitotic cell cycle; proteolysis involved in cellular protein catabolic process; protein polyubiquitination; M/G1 transition of mitotic cell cycle; mitotic cell cycle; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of cellular amino acid metabolic process; apoptotic process; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mRNA metabolic process; cellular nitrogen compound met | |
| PSMB10 | S phase of mitotic cell cycle; apoptotic process; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; mitotic cell cycle; M/G1 transition of mitotic cell cycle; cell cycle checkpoint; G1/S transition of mitotic cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; proteolysis involved in cellular protein catabolic process; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; interspecies interaction between organisms; small molecule metabolic process; regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular nitrogen compoun | |
| PSMB11 | S phase of mitotic cell cycle; cell cycle checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of apoptotic process; small molecule metabolic process; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; proteolysis involved in cellular protein catabolic process; M/G1 transition of mitotic cell cycle; mRNA metabolic process; RNA metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; viral reproduction; gene expression; apoptotic process; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC | |
| PSMB2 | antigen processing and presentation of peptide antigen via MHC class I; regulation of cellular amino acid metabolic process; proteolysis involved in cellular protein catabolic process; protein polyubiquitination; M/G1 transition of mitotic cell cycle; mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; interspecies interaction between organisms; small molecule metabolic process; cell cycle checkpoint; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular nitroge | |
| PSMC2 | RNA metabolic process; mRNA metabolic process; protein catabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; interspecies interaction between organisms; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cellular nitrogen compound metabolic process; gene expression; viral reproduction; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; protein polyubiquitination; M/G1 transition of mitotic cell cycle; mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; ATP catabolic process; ubiquitin-dependent | |
| PSMC3 | viral reproduction; RNA metabolic process; mRNA metabolic process; protein catabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; interspecies interaction between organisms; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; protein polyubiquitination; M/G1 transition of mitotic cell cycle; mitotic cell cycle; blastocyst development; antigen processing an | |
| PSMC3IP | positive regulation of transcription from RNA polymerase II promoter; meiosis; DNA recombination | |
| PSMC4 | protein catabolic process; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; regulation of cellular amino acid metabolic process; ATP catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; blastocyst development; mitotic cell cycle; M/G1 transition of mitotic cell cycle; protein polyubiquitination; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint; proteolysis; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activ | |
| PSMC6 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; gene expression; viral reproduction; RNA metabolic process; mRNA metabolic process; protein catabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of apoptotic process; apoptotic process; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; protein polyubiquitination; M/G1 transition of mitotic cell cycle; mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via M | |
| PSMD11 | gene expression; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; small molecule metabolic process; regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mRNA metabolic process; RNA metabolic process; viral reproduction; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; mitotic cell cycle; M/G1 transition of mitotic cell cyc | |
| PSMD3 | antigen processing and presentation of peptide antigen via MHC class I; mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; small molecule metabolic process; regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of protein catabolic process; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mRNA metabolic process; RNA metabolic process; gene expression; viral reproduction; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of cellular amino acid metabolic process; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; protein polyubi | |
| PSMD4 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; gene expression; viral reproduction; small molecule metabolic process; regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mRNA metabolic process; RNA metabolic process; cell cycle checkpoint; G1/S transition of mitotic cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; regulation of cellular amino acid metabolic process; S phase of mitotic cell cycle; protein polyubiquitination; M/G1 transition of mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen | |
| PSMD6 | gene expression; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mRNA metabolic process; RNA metabolic process; viral reproduction; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; protein polyubiquitination; M/G1 transition of mitotic cell cycle; mitotic cell cycle; regulation of cellular amino acid metabolic process; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; proteolysis; ATP catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; | |
| PSMD7 | RNA metabolic process; mRNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; viral reproduction; gene expression; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; mitotic cell cycle; M/G1 transition of mitotic cell cyc | |
| PSME1 | mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; cell cycle checkpoint; M/G1 transition of mitotic cell cycle; protein polyubiquitination; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; regulation of cellular amino acid metabolic process; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; small molecule metabolic process; regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mRNA metabolic process; RNA metabolic process; viral reproduction; gene e | |
| PSME2 | mRNA metabolic process; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; RNA metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cellular nitrogen compound metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; regulation of apoptotic process; small molecule metabolic process; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; viral reproduction; gene expression; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-depend | |
| PSME4 | antigen processing and presentation of peptide antigen via MHC class I; multicellular organismal development; cell differentiation; mRNA metabolic process; RNA metabolic process; apoptotic process; viral reproduction; S phase of mitotic cell cycle; cell cycle checkpoint; spermatogenesis; regulation of cellular amino acid metabolic process; protein polyubiquitination; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular nitrogen compound metabolic process; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of apoptotic process; small molecule metabolic process; gene expression; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; mitotic cell cycle; M/G1 transition of mitotic cell cycle; regula | |
| PSMG2 | regulation of apoptotic process; proteasome assembly; regulation of cell cycle; mitotic cell cycle spindle assembly checkpoint | |
| PSPC1 | regulation of transcription, DNA-dependent | |
| PSTK | translation; selenocysteine incorporation | |
| PTAFR | cytokine production; interferon-gamma-mediated signaling pathway; phosphatidylinositol-mediated signaling; inositol trisphosphate biosynthetic process; response to lipopolysaccharide; cytokine-mediated signaling pathway; G-protein coupled receptor signaling pathway; immune response; inflammatory response; chemotaxis; pattern recognition receptor signaling pathway | |
| PTBP1 | mRNA processing; alternative nuclear mRNA splicing, via spliceosome; regulation of alternative nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; negative regulation of RNA splicing; negative regulation of nuclear mRNA splicing, via spliceosome; negative regulation of muscle cell differentiation | |
| PTBP2 | mRNA splice site selection; mRNA processing; negative regulation of RNA splicing | |
| PTBP3 | negative regulation of RNA splicing; anatomical structure morphogenesis; mRNA processing; erythrocyte maturation; cell differentiation | |
| PTCD3 | - | |
| PTCH1 | response to chlorate; regulation of smoothened signaling pathway; epidermis development; brain development; pattern specification process; regulation of mitotic cell cycle; smoothened signaling pathway; regulation of growth; cellular response to cholesterol; somite development; cell differentiation involved in kidney development; mammary gland epithelial cell differentiation; mammary gland duct morphogenesis; pharyngeal system development; negative regulation of epithelial cell proliferation; negative regulation of smoothened signaling pathway; negative regulation of osteoblast differentiation; keratinocyte proliferation; negative regulation of sequence-specific DNA binding transcription factor activity; glucose homeostasis; negative regulation of multicellular organism growth; organ morphogenesis; hindlimb morphogenesis; limb morphogenesis; regulation of protein localization; mammary gland development; embryonic limb morphogenesis; neural plate axis specification; dorsal/ventral neural tube patterning; neura | |
| PTCHD1 | smoothened signaling pathway; cognition | |
| PTCHD2 | cholesterol homeostasis; regulation of lipid transport; smoothened signaling pathway | |
| PTDSS1 | phosphatidylserine biosynthetic process; phospholipid biosynthetic process | |
| PTEN | positive regulation of cell proliferation; negative regulation of cell migration; negative regulation of cell proliferation; fibroblast growth factor receptor signaling pathway; regulation of neuron projection development; protein kinase B signaling cascade; negative regulation of apoptotic process; peptidyl-tyrosine dephosphorylation; regulation of myeloid cell apoptosis; negative regulation of cyclin-dependent protein kinase activity involved in G1/S; regulation of protein stability; cell proliferation; heart development; central nervous system development; epidermal growth factor receptor signaling pathway; activation of mitotic anaphase-promoting complex activity; induction of apoptosis; lipid metabolic process; protein dephosphorylation; regulation of B cell apoptosis; negative regulation of protein phosphorylation; angiogenesis; regulation of cyclin-dependent protein kinase activity; inositol phosphate dephosphorylation; cell migration; negative regulation of G1/S transition of mitotic cell cycle; posit | |
| PTGDR | G-protein coupled receptor signaling pathway; male sex determination; sleep; adenosine metabolic process; cellular response to prostaglandin D stimulus | |
| PTGER2 | G-protein coupled receptor signaling pathway; regulation of cell proliferation | |
| PTGFRN | lipid particle organization | |
| PTGIR | G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; blood coagulation | |
| PTGS1 | response to organic nitrogen; aging; response to oxidative stress; xenobiotic metabolic process; prostanoid metabolic process; fatty acid biosynthetic process; lipid metabolic process; prostaglandin biosynthetic process; positive regulation of smooth muscle contraction; positive regulation of vasoconstriction; small molecule metabolic process; regulation of cell proliferation; negative regulation of epinephrine secretion; cyclooxygenase pathway; negative regulation of norepinephrine secretion; regulation of blood pressure; response to corticosterone stimulus | |
| PTH2 | neuropeptide signaling pathway | |
| PTH2R | G-protein coupled receptor signaling pathway | |
| PTHLH | positive regulation of cell proliferation; skeletal system development; endochondral ossification; osteoblast development; activation of adenylate cyclase activity by G-protein signaling pathway; cell-cell signaling; endoderm development; female pregnancy; epidermis development; negative regulation of cell proliferation; surfactant homeostasis; negative regulation of chondrocyte differentiation; epithelial cell differentiation; positive regulation of cAMP biosynthetic process; protein processing; regulation of gene expression; nipple sheath formation; mammary gland bud elongation; negative regulation of sequence-specific DNA binding transcription factor activity; cAMP metabolic process; lung alveolus development | |
| PTK2 | platelet activation; central nervous system neuron axonogenesis; regulation of cell adhesion mediated by integrin; netrin-activated signaling pathway; establishment of nucleus localization; regulation of cell proliferation; negative regulation of apoptotic process; protein phosphorylation; integrin-mediated signaling pathway; signal complex assembly; cellular component disassembly involved in apoptosis; apoptotic process; positive regulation of protein kinase activity; establishment of cell polarity; peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; regulation of endothelial cell migration; embryo development; regulation of cell shape; positive regulation of cell proliferation; blood coagulation; axon guidance; regulation of Rho GTPase activity; positive regulation of cell migration; extracellular matrix organization; protein autophosphorylation; regulation of focal adhesion assembly; positive regulation of protein kinase B signaling cascade; negative regulation | |
| PTK2B | cell differentiation; regulation of establishment of cell polarity; response to hydrogen peroxide; response to drug; response to cocaine; tumor necrosis factor-mediated signaling pathway; regulation of inositol trisphosphate biosynthetic process; activation of Rac GTPase activity; positive regulation of actin filament polymerization; negative regulation of bone mineralization; positive regulation of cell migration; positive regulation of cell growth; regulation of cell adhesion; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; peptidyl-tyrosine phosphorylation; glial cell proliferation; positive regulation of neuron projection development; regulation of macrophage chemotaxis; response to organic nitrogen; response to lithium ion; response to glucose stimulus; response to hormone stimulus; response to mechanical stimulus; regulation of cell shape; positive regulation of cell proliferation; integrin-mediated signaling pathway; positive regulation of JUN kinase acti | |
| PTK7 | cochlea morphogenesis; cellular response to retinoic acid; positive regulation of neuron projection development; cell migration; actin cytoskeleton reorganization; wound healing; establishment of epithelial cell apical/basal polarity; convergent extension; canonical Wnt receptor signaling pathway; lung-associated mesenchyme development; planar cell polarity pathway involved in neural tube closure; signal transduction; cell adhesion; axis elongation; neural tube closure; establishment of planar polarity | |
| PTP4A3 | - | |
| PTPDC1 | - | |
| PTPN1 | actin cytoskeleton reorganization; negative regulation of insulin receptor signaling pathway; blood coagulation; regulation of signal transduction; cytokine-mediated signaling pathway; regulation of endocytosis; platelet activation; peptidyl-tyrosine dephosphorylation; JAK-STAT cascade involved in growth hormone signaling pathway; regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; interferon-gamma-mediated signaling pathway | |
| PTPN11 | regulation of cell adhesion mediated by integrin; T cell costimulation; cytokine-mediated signaling pathway; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; blood coagulation; axon guidance; epidermal growth factor receptor signaling pathway; peptidyl-tyrosine dephosphorylation; ephrin receptor signaling pathway; leukocyte migration; interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway | |
| PTPN12 | protein dephosphorylation | |
| PTPN14 | lymphangiogenesis; protein dephosphorylation; peptidyl-tyrosine dephosphorylation | |
| PTPN18 | protein dephosphorylation | |
| PTPN21 | peptidyl-tyrosine dephosphorylation; protein dephosphorylation | |
| PTPN22 | negative regulation of T cell receptor signaling pathway; regulation of B cell receptor signaling pathway; regulation of innate immune response; phosphoanandamide dephosphorylation; peptidyl-tyrosine dephosphorylation; regulation of natural killer cell proliferation; T cell differentiation; protein dephosphorylation; negative regulation of T cell activation | |
| PTPN23 | cilium morphogenesis; cell projection organization | |
| PTPN4 | protein dephosphorylation | |
| PTPN5 | protein dephosphorylation; peptidyl-tyrosine dephosphorylation | |
| PTPN9 | protein dephosphorylation; peptidyl-tyrosine dephosphorylation | |
| PTPRA | insulin receptor signaling pathway; peptidyl-tyrosine dephosphorylation; axon guidance; protein phosphorylation | |
| PTPRC | bone marrow development; negative regulation of T cell mediated cytotoxicity; negative regulation of cytokine-mediated signaling pathway; hemopoietic progenitor cell differentiation; immunoglobulin biosynthetic process; negative regulation of protein kinase activity; protein dephosphorylation; negative regulation of cell adhesion involved in substrate-bound cell migration; cell surface receptor signaling pathway; regulation of cell cycle; T cell differentiation; positive regulation of B cell proliferation; regulation of S phase; peptidyl-tyrosine dephosphorylation; B cell proliferation; positive regulation of T cell proliferation; positive regulation of stem cell proliferation; positive regulation of hematopoietic stem cell migration; dephosphorylation; defense response to virus; release of sequestered calcium ion into cytosol; positive regulation of antigen receptor-mediated signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; stem cell development; positive regulation of | |
| PTPRCAP | defense response | |
| PTPRD | phosphate-containing compound metabolic process; transmembrane receptor protein tyrosine phosphatase signaling pathway; protein dephosphorylation | |
| PTPRE | transmembrane receptor protein tyrosine phosphatase signaling pathway; regulation of mast cell activation; negative regulation of insulin receptor signaling pathway; protein dephosphorylation; protein phosphorylation | |
| PTPRF | negative regulation of nerve growth factor receptor signaling pathway; negative regulation of cytokine-mediated signaling pathway; cell adhesion; homophilic cell adhesion; transmembrane receptor protein tyrosine phosphatase signaling pathway; negative regulation of insulin receptor signaling pathway; regulation of synapse structure and activity; negative regulation of cell proliferation; positive regulation of dendrite morphogenesis; nervous system development; negative regulation of cell projection organization; peptidyl-tyrosine dephosphorylation; negative regulation of epidermal growth factor receptor signaling pathway; positive regulation of neuron apoptosis | |
| PTPRG | peptidyl-tyrosine dephosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway | |
| PTPRH | apoptotic process; protein dephosphorylation | |
| PTPRK | signal transduction; protein dephosphorylation; negative regulation of keratinocyte proliferation; negative regulation of cell proliferation; transforming growth factor beta receptor signaling pathway; cell adhesion; focal adhesion assembly; negative regulation of transcription, DNA-dependent; negative regulation of cell cycle; peptidyl-tyrosine dephosphorylation; cellular response to UV; cellular response to reactive oxygen species; protein localization at cell surface; negative regulation of cell migration; cell migration | |
| PTPRM | protein dephosphorylation; negative regulation of endothelial cell proliferation; neuron projection development; negative regulation of angiogenesis; retina layer formation; negative regulation of endothelial cell migration; signal transduction; homophilic cell adhesion; cell adhesion; retinal ganglion cell axon guidance; peptidyl-tyrosine dephosphorylation; response to drug; positive regulation of vasodilation | |
| PTPRN | response to glucose stimulus; response to reactive oxygen species; cytokine-mediated signaling pathway; response to insulin stimulus; response to estrogen stimulus; response to cAMP | |
| PTPRN2 | protein dephosphorylation; negative regulation of GTPase activity | |
| PTPRO | glomerulus development; cell morphogenesis; monocyte chemotaxis; regulation of glomerular filtration; negative regulation of glomerular filtration; protein dephosphorylation; axon guidance; negative regulation of cell-substrate adhesion; negative regulation of neuron projection development; lamellipodium assembly; peptidyl-tyrosine dephosphorylation; slit diaphragm assembly; glomerular visceral epithelial cell differentiation; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of retinal ganglion cell axon guidance | |
| PTPRR | in utero embryonic development; protein dephosphorylation; nervous system development; neuron differentiation; peptidyl-tyrosine dephosphorylation | |
| PTPRS | hippocampus development; cell adhesion; cerebral cortex development; corpus callosum development; cerebellum development; spinal cord development | |
| PTPRT | protein dephosphorylation; cell adhesion; homophilic cell adhesion; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; peptidyl-tyrosine dephosphorylation | |
| PTPRU | canonical Wnt receptor signaling pathway; cell-cell adhesion; peptidyl-tyrosine dephosphorylation; protein localization at cell surface; homotypic cell-cell adhesion; cell adhesion; cell differentiation; negative regulation of cell migration; transmembrane receptor protein tyrosine phosphatase signaling pathway; protein dephosphorylation; negative regulation of cell proliferation | |
| PTPRZ1 | central nervous system development; protein dephosphorylation; axonogenesis | |
| PTRF | transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; gene expression; regulation of transcription, DNA-dependent | |
| PTRH1 | - | |
| PTX3 | positive regulation of phagocytosis; positive regulation of nitric oxide biosynthetic process; opsonization; inflammatory response; response to yeast | |
| PTX4 | - | |
| PUM2 | regulation of translation | |
| PURA | negative regulation of transcription, DNA-dependent; nervous system development; negative regulation of translation; positive regulation of cell proliferation; DNA-dependent DNA replication initiation; DNA unwinding involved in replication | |
| PURG | - | |
| PUS3 | tRNA processing; tRNA pseudouridine synthesis | |
| PUS7 | tRNA processing; pseudouridine synthesis | |
| PUS7L | tRNA processing; pseudouridine synthesis | |
| PVR | cell-cell adhesion; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; susceptibility to T cell mediated cytotoxicity; regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity; cell-cell junction organization; interspecies interaction between organisms; susceptibility to natural killer cell mediated cytotoxicity; adherens junction organization; cell junction assembly; cell migration | |
| PVRL1 | retina development in camera-type eye; regulation of synapse assembly; cell adhesion; entry of virus into host cell; cell-cell junction organization; interspecies interaction between organisms; adherens junction organization; cell junction assembly; cell-cell adhesion; axon guidance; heterophilic cell-cell adhesion; homophilic cell adhesion; immune response; lens morphogenesis in camera-type eye | |
| PVRL3 | lens morphogenesis in camera-type eye; cell-cell junction organization; retina morphogenesis in camera-type eye; cell junction assembly; adherens junction organization; homophilic cell adhesion; fertilization | |
| PWP1 | transcription, DNA-dependent | |
| PWP2 | signal transduction | |
| PWWP2B | - | |
| PXK | regulation of synaptic transmission; negative regulation of ion transport; negative regulation of ATPase activity; cell communication; inflammatory response; protein phosphorylation | |
| PXYLP1 | - | |
| PYCR1 | proline biosynthetic process; response to stress; cellular response to oxidative stress; cellular amino acid biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| PYCRL | proline biosynthetic process; cellular amino acid biosynthetic process | |
| PYGB | glycogen catabolic process; glucose metabolic process; small molecule metabolic process; carbohydrate metabolic process | |
| PYGM | cellular calcium ion homeostasis; response to hypoxia; carbohydrate metabolic process; glucose metabolic process; small molecule metabolic process; response to cAMP; glycogen metabolic process; glycogen catabolic process | |
| PYGO1 | post-embryonic development; kidney development; Wnt receptor signaling pathway | |
| PYHIN1 | cell cycle | |
| PYM1 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; positive regulation of translation | |
| PYROXD2 | - | |
| PZP | negative regulation of endopeptidase activity; female pregnancy | |
| QARS | gene expression; glutaminyl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| QKI | RNA splicing; vasculogenesis; mRNA processing; regulation of translation; transport; multicellular organismal development; positive regulation of gene expression; myelination; muscle cell differentiation; long-chain fatty acid biosynthetic process; mRNA transport | |
| QPCTL | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; proteolysis | |
| QRFPR | G-protein coupled receptor signaling pathway | |
| QRICH1 | - | |
| QRICH2 | - | |
| QSER1 | - | |
| QTRT1 | tRNA modification; queuosine biosynthetic process | |
| QTRTD1 | queuosine biosynthetic process | |
| R3HCC1L | - | |
| R3HDM1 | - | |
| R3HDM2 | - | |
| R3HDML | - | |
| RAB10 | small GTPase mediated signal transduction; protein transport | |
| RAB11FIP2 | protein transport; establishment of cell polarity | |
| RAB11FIP3 | vesicle-mediated transport; endocytic recycling; cell cycle; cytokinesis | |
| RAB11FIP5 | protein transport | |
| RAB14 | small GTPase mediated signal transduction; neurotransmitter secretion; body fluid secretion; fibroblast growth factor receptor signaling pathway; protein transport; vesicle-mediated transport; regulation of protein localization; apical protein localization; intracellular transport; Golgi to endosome transport; GTP catabolic process; embryo development | |
| RAB20 | small GTPase mediated signal transduction; protein transport | |
| RAB25 | positive regulation of cell proliferation; pseudopodium organization; protein transport; small GTPase mediated signal transduction | |
| RAB26 | exocrine system development; regulation of exocytosis; protein transport; small GTPase mediated signal transduction | |
| RAB34 | protein transport; small GTPase mediated signal transduction; endocytosis | |
| RAB35 | endosome transport; protein transport; protein localization; small GTPase mediated signal transduction; GTP catabolic process; cytokinesis | |
| RAB37 | small GTPase mediated signal transduction; protein transport | |
| RAB39A | small GTPase mediated signal transduction; protein transport | |
| RAB3C | small GTPase mediated signal transduction; protein transport; regulation of exocytosis | |
| RAB3GAP1 | brain development; camera-type eye development; hypothalamus development; face morphogenesis; regulation of GTPase activity; positive regulation of Rab GTPase activity | |
| RAB3GAP2 | regulation of GTPase activity; positive regulation of GTPase activity; positive regulation of catalytic activity; intracellular protein transport | |
| RAB3IL1 | - | |
| RAB3IP | cilium assembly; protein localization to organelle; protein transport; Golgi to plasma membrane transport | |
| RAB40B | small GTPase mediated signal transduction; protein transport | |
| RAB4A | regulation of endocytosis; GTP catabolic process; small GTPase mediated signal transduction | |
| RAB4B | small GTPase mediated signal transduction; protein transport; GTP catabolic process; vesicle-mediated transport | |
| RAB5C | GTP catabolic process; endosome organization; small GTPase mediated signal transduction; protein transport; regulation of endocytosis | |
| RAB6B | vesicle-mediated transport; protein transport; small GTPase mediated signal transduction; retrograde vesicle-mediated transport, Golgi to ER; GTP catabolic process | |
| RAB7A | small GTPase mediated signal transduction; endocytosis; endosome to lysosome transport; protein transport; early endosome to late endosome transport; phagosome maturation; epidermal growth factor catabolic process; GTP catabolic process | |
| RAB8A | Golgi vesicle fusion to target membrane; cilium assembly; protein transport; small GTPase mediated signal transduction; vesicle docking involved in exocytosis | |
| RAB8B | positive regulation of corticotropin secretion; GTP catabolic process; small GTPase mediated signal transduction; protein transport; positive regulation of cell projection organization; adherens junction organization | |
| RAB9B | Golgi to endosome transport; small GTPase mediated signal transduction; protein transport | |
| RABEP1 | endocytosis; apoptotic process; cellular membrane fusion; protein transport | |
| RABEPK | receptor-mediated endocytosis; vesicle docking involved in exocytosis | |
| RABGAP1 | positive regulation of GTPase activity; cell cycle | |
| RABGAP1L | positive regulation of Rab GTPase activity; regulation of protein localization | |
| RABGEF1 | endocytosis; protein transport | |
| RAD18 | negative regulation of DNA recombination; response to UV; DNA repair; spermatogenesis | |
| RAD21 | double-strand break repair; mitotic cell cycle; protein localization to chromatin; cell division; reciprocal meiotic recombination; mitotic metaphase/anaphase transition; chromosome segregation; apoptotic process; regulation of transcription from RNA polymerase II promoter; M phase of mitotic cell cycle; mitotic prometaphase; DNA recombination | |
| RAD23A | nucleotide-excision repair; regulation of proteasomal ubiquitin-dependent protein catabolic process; interspecies interaction between organisms; positive regulation of viral genome replication | |
| RAD50 | DNA recombination; double-strand break repair; DNA repair; double-strand break repair via homologous recombination; regulation of mitotic recombination; positive regulation of protein autophosphorylation; telomere maintenance; reciprocal meiotic recombination; telomere maintenance via telomerase; cell cycle; positive regulation of kinase activity; meiosis; DNA duplex unwinding | |
| RAD51AP2 | - | |
| RAD51D | DNA repair; DNA recombination; reciprocal meiotic recombination | |
| RAD54L | response to ionizing radiation; response to drug; chromosome organization; DNA recombination; DNA repair; meiosis; double-strand break repair via homologous recombination | |
| RAD9A | DNA repair; DNA replication; response to DNA damage stimulus; positive regulation of apoptotic process; cellular response to ionizing radiation; DNA damage checkpoint; cell cycle checkpoint; DNA replication checkpoint | |
| RADIL | cell adhesion; multicellular organismal development; signal transduction | |
| RAET1E | regulation of immune response; antigen processing and presentation; immune response | |
| RAF1 | regulation of cell motility; negative regulation of cell proliferation; nerve growth factor receptor signaling pathway; regulation of cell differentiation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; regulation of apoptotic process; wound healing; insulin receptor signaling pathway; axon guidance; synaptic transmission; Ras protein signal transduction; small GTPase mediated signal transduction; epidermal growth factor receptor signaling pathway; signal transduction; heart development; blood coagulation; cell proliferation; cytoskeleton organization; apoptotic process; protein phosphorylation; regulation of Rho protein signal transduction; response to hypoxia; activation of MAPKK activity; MAPK cascade; fibroblast growth factor receptor signaling pathway; platelet activation; negative regulation of protein complex assembly; positive regulation of peptidyl-serine phosphorylation | |
| RAG1 | chromatin modification; V(D)J recombination; T cell differentiation in thymus; B cell differentiation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; protein autoubiquitination; negative regulation of thymocyte apoptosis; death; histone monoubiquitination; immune response; DNA recombination; pre-B cell allelic exclusion | |
| RAG2 | B cell homeostatic proliferation; positive regulation of organ growth; V(D)J recombination; T cell differentiation in thymus; B cell differentiation; chromatin modification; somatic diversification of immunoglobulins; DNA recombination; T cell lineage commitment; pre-B cell allelic exclusion; B cell lineage commitment | |
| RAI1 | skeletal system development; regulation of transcription from RNA polymerase II promoter; negative regulation of multicellular organism growth | |
| RAI14 | - | |
| RAI2 | embryo development | |
| RALA | actin cytoskeleton reorganization; cytokinesis; chemotaxis; cell cycle; signal transduction; Ras protein signal transduction; regulation of exocytosis; interspecies interaction between organisms; nerve growth factor receptor signaling pathway; positive regulation of filopodium assembly; membrane raft localization | |
| RALBP1 | positive regulation of GTPase activity; positive regulation of Cdc42 GTPase activity; regulation of GTPase activity; small GTPase mediated signal transduction; signal transduction; chemotaxis; ATP catabolic process; regulation of small GTPase mediated signal transduction; transport; positive regulation of Rac GTPase activity | |
| RALGAPB | activation of Ral GTPase activity; regulation of small GTPase mediated signal transduction | |
| RALGDS | signal transduction; small GTPase mediated signal transduction; Ras protein signal transduction; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction | |
| RALY | nuclear mRNA splicing, via spliceosome; RNA splicing | |
| RANBP17 | mRNA transport; protein import into nucleus; intracellular protein transport | |
| RANBP2 | protein transport; regulation of glucose transport; hexose transport; protein import into nucleus; protein folding; carbohydrate metabolic process; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle; viral reproduction; protein sumoylation; cytokine-mediated signaling pathway; small molecule metabolic process; intracellular transport; mRNA transport; transmembrane transport; glucose transport | |
| RANBP3 | protein transport; intracellular transport | |
| RANBP6 | protein transport | |
| RANBP9 | axon guidance; protein complex assembly; microtubule nucleation | |
| RAPGEF2 | regulation of small GTPase mediated signal transduction; MAPK cascade; regulation of synaptic plasticity; intracellular signal transduction; positive regulation of Rap GTPase activity; cAMP-mediated signaling; small GTPase mediated signal transduction | |
| RAPGEF3 | regulation of catalytic activity; platelet activation; cell proliferation; blood coagulation; signal transduction; small molecule metabolic process; regulation of protein phosphorylation; regulation of insulin secretion; regulation of small GTPase mediated signal transduction; energy reserve metabolic process | |
| RAPGEF4 | energy reserve metabolic process; G-protein coupled receptor signaling pathway; regulation of protein phosphorylation; blood coagulation; regulation of small GTPase mediated signal transduction; heart development; regulation of insulin secretion; cAMP-mediated signaling; platelet activation; small molecule metabolic process; regulation of dendrite development; regulation of exocytosis; calcium ion-dependent exocytosis; positive regulation of smooth muscle cell migration; regulation of catalytic activity; negative regulation of synaptic transmission | |
| RAPGEF6 | signal transduction; regulation of small GTPase mediated signal transduction; regulation of GTPase activity; Ras protein signal transduction | |
| RAPGEFL1 | G-protein coupled receptor signaling pathway; nervous system development; small GTPase mediated signal transduction | |
| RAPH1 | signal transduction; cell-matrix adhesion | |
| RAPSN | positive regulation of neuron apoptosis; synaptic transmission, cholinergic; synaptic transmission | |
| RARA | signal transduction; germ cell development; spermatogenesis; response to estradiol stimulus; positive regulation of cell proliferation; protein phosphorylation; cellular response to estrogen stimulus; gene expression; intracellular estrogen receptor signaling pathway; negative regulation of granulocyte differentiation; cellular response to retinoic acid; response to retinoic acid; negative regulation of interferon-gamma production; negative regulation of tumor necrosis factor production; positive regulation of interleukin-13 production; positive regulation of interleukin-4 production; ventricular cardiac muscle cell differentiation; positive regulation of T-helper 2 cell differentiation; positive regulation of cell cycle; negative regulation of transcription from RNA polymerase II promoter; ureteric bud development; growth plate cartilage development; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymera | |
| RARB | embryonic digestive tract development; retinoic acid receptor signaling pathway; gene expression; signal transduction | |
| RARRES2 | retinoid metabolic process; positive regulation of macrophage chemotaxis; brown fat cell differentiation; embryonic digestive tract development; in utero embryonic development | |
| RARS | arginyl-tRNA aminoacylation; gene expression; tRNA aminoacylation for protein translation | |
| RARS2 | tRNA aminoacylation for protein translation; arginyl-tRNA aminoacylation; gene expression | |
| RASA1 | negative regulation of cell-matrix adhesion; negative regulation of cell adhesion; signal transduction; vasculogenesis; embryo development; regulation of actin filament polymerization; positive regulation of Ras GTPase activity; regulation of cell shape; negative regulation of neuron apoptosis; positive regulation of anti-apoptosis; negative regulation of Ras protein signal transduction; intracellular signal transduction; regulation of small GTPase mediated signal transduction; regulation of RNA metabolic process; cytokinesis | |
| RASA2 | signal transduction; positive regulation of Ras GTPase activity; intracellular signal transduction; negative regulation of Ras protein signal transduction; regulation of small GTPase mediated signal transduction | |
| RASA3 | negative regulation of Ras protein signal transduction; regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity; intracellular signal transduction; positive regulation of Ras GTPase activity; signal transduction | |
| RASAL2 | regulation of small GTPase mediated signal transduction; negative regulation of Ras protein signal transduction; positive regulation of Ras GTPase activity; signal transduction | |
| RASEF | protein transport; small GTPase mediated signal transduction | |
| RASGEF1A | regulation of small GTPase mediated signal transduction; cell migration | |
| RASGEF1B | regulation of small GTPase mediated signal transduction | |
| RASGRF1 | regulation of synaptic plasticity; nerve growth factor receptor signaling pathway; positive regulation of Ras protein signal transduction; regulation of Ras protein signal transduction; regulation of Rho protein signal transduction; regulation of Rac protein signal transduction; regulation of neuronal synaptic plasticity; activation of Rac GTPase activity; positive regulation of Ras GTPase activity; neuron projection development; induction of apoptosis by extracellular signals; cell proliferation; long-term memory; synaptic transmission; small GTPase mediated signal transduction; signal transduction; apoptotic process; regulation of small GTPase mediated signal transduction | |
| RASGRF2 | regulation of Rho protein signal transduction; small GTPase mediated signal transduction; synaptic transmission; induction of apoptosis by extracellular signals; apoptotic process; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction | |
| RASGRP2 | regulation of small GTPase mediated signal transduction; platelet activation; blood coagulation; Ras protein signal transduction; regulation of cell growth; signal transduction | |
| RASL10B | signal transduction; small GTPase mediated signal transduction | |
| RASL11A | positive regulation of transcription from RNA polymerase I promoter; small GTPase mediated signal transduction; signal transduction; regulation of transcription, DNA-dependent | |
| RASL11B | small GTPase mediated signal transduction; signal transduction | |
| RASSF1 | Ras protein signal transduction; intracellular signal transduction; positive regulation of protein ubiquitination; cell cycle arrest; protein stabilization; negative regulation of cell cycle arrest; response to DNA damage stimulus; cell cycle | |
| RASSF6 | regulation of apoptotic process; signal transduction | |
| RAVER2 | - | |
| RB1 | negative regulation of S phase of mitotic cell cycle; negative regulation of smoothened signaling pathway; positive regulation of macrophage differentiation; positive regulation of mitotic metaphase/anaphase transition; enucleate erythrocyte differentiation; myoblast differentiation; interspecies interaction between organisms; regulation of lipid kinase activity; negative regulation of sequence-specific DNA binding transcription factor activity; regulation of centromere complex assembly; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; digestive tract development; cell morphogenesis involved in neuron differentiation; negative regulation of epithelial cell proliferation; striated muscle cell differentiation; cell division; G1 phase; neuron apoptosis; protein localization to chromosome, centromeric region; regulation of cohesin localization to chromatin; negative regulation of transcri | |
| RB1CC1 | negative regulation of apoptotic process; regulation of transcription, DNA-dependent; cell cycle; positive regulation of cell size; JNK cascade; heart development; regulation of autophagy; positive regulation of protein phosphorylation; liver development; autophagic vacuole assembly | |
| RBAK | negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| RBBP6 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process | |
| RBBP8 | cell cycle checkpoint; G1/S transition of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; blastocyst hatching; DNA repair; regulation of transcription from RNA polymerase II promoter; meiosis; DNA double-strand break processing involved in repair via single-strand annealing | |
| RBBP9 | regulation of cell proliferation | |
| RBFOX1 | mRNA processing; RNA splicing; RNA transport | |
| RBL1 | chromatin modification; G1 phase of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; regulation of transcription, DNA-dependent; regulation of lipid kinase activity; interspecies interaction between organisms; regulation of cell cycle | |
| RBL2 | regulation of cell cycle; regulation of lipid kinase activity; chromatin modification; regulation of transcription, DNA-dependent; mitotic cell cycle; G1 phase of mitotic cell cycle | |
| RBM10 | mRNA processing; RNA splicing | |
| RBM12 | - | |
| RBM12B | - | |
| RBM14 | glucocorticoid receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; DNA replication; intracellular estrogen receptor signaling pathway; histone deacetylation; response to hormone stimulus; regulation of transcription, DNA-dependent; DNA recombination; DNA repair | |
| RBM15B | mRNA processing; negative regulation of transcription, DNA-dependent; interspecies interaction between organisms; RNA splicing; nucleocytoplasmic transport; regulation of transcription, DNA-dependent; regulation of alternative nuclear mRNA splicing, via spliceosome | |
| RBM17 | RNA splicing; mRNA processing | |
| RBM19 | multicellular organismal development; positive regulation of embryonic development | |
| RBM23 | mRNA processing | |
| RBM24 | cell differentiation; regulation of mRNA stability; regulation of myotube differentiation | |
| RBM25 | RNA splicing; apoptotic process; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome | |
| RBM26 | mRNA processing; negative regulation of phosphatase activity | |
| RBM27 | mRNA processing | |
| RBM3 | positive regulation of translation; production of miRNAs involved in gene silencing by miRNA; response to cold; regulation of translation; RNA processing | |
| RBM39 | RNA processing; regulation of transcription, DNA-dependent; RNA splicing; mRNA processing | |
| RBM42 | - | |
| RBM46 | - | |
| RBM47 | - | |
| RBM5 | regulation of alternative nuclear mRNA splicing, via spliceosome; negative regulation of cell proliferation; spliceosome assembly; RNA splicing; nuclear mRNA splicing, via spliceosome; RNA processing; positive regulation of apoptotic process; gene expression | |
| RBM6 | RNA processing | |
| RBMX | membrane protein ectodomain proteolysis; nuclear mRNA splicing, via spliceosome; RNA splicing; positive regulation of nuclear mRNA splicing, via spliceosome; protein homooligomerization; regulation of alternative nuclear mRNA splicing, via spliceosome; cellular response to interleukin-1; transcription from RNA polymerase II promoter; negative regulation of nuclear mRNA splicing, via spliceosome; gene expression; positive regulation of transcription from RNA polymerase II promoter | |
| RBMXL2 | - | |
| RBP3 | visual perception; transport; lipid metabolic process; proteolysis | |
| RBP4 | positive regulation of immunoglobulin secretion; transmembrane transport; cardiac muscle tissue development; retina development in camera-type eye; negative regulation of cardiac muscle cell proliferation; embryonic retina morphogenesis in camera-type eye; uterus development; vagina development; urinary bladder development; heart trabecula formation; response to stimulus; heart development; male gonad development; embryo development; maintenance of gastrointestinal epithelium; lung development; detection of light stimulus involved in visual perception; positive regulation of insulin secretion; response to retinoic acid; response to insulin stimulus; spermatogenesis; gluconeogenesis; eye development; retinol transport; retinol metabolic process; retinal metabolic process; glucose homeostasis; response to ethanol; embryonic organ morphogenesis; embryonic skeletal system development; female genitalia morphogenesis | |
| RBPJ | DNA recombination; positive regulation of transcription of Notch receptor target; gene expression; negative regulation of transcription, DNA-dependent; Notch signaling pathway; regulation of transcription, DNA-dependent | |
| RBPJL | regulation of transcription, DNA-dependent; signal transduction | |
| RC3H1 | regulation of T cell receptor signaling pathway; regulation of germinal center formation; negative regulation of B cell proliferation; negative regulation of activated T cell proliferation; negative regulation of T-helper cell differentiation; regulation of mRNA stability; nuclear-transcribed mRNA catabolic process; cytoplasmic mRNA processing body assembly; protein ubiquitination; posttranscriptional regulation of gene expression; negative regulation of germinal center formation | |
| RC3H2 | - | |
| RCAN1 | response to mechanical stimulus; signal transduction; response to estrogen stimulus; regulation of transcription, DNA-dependent; central nervous system development; blood circulation; calcium-mediated signaling; regulation of phosphoprotein phosphatase activity; skeletal muscle fiber development; negative regulation of smooth muscle cell differentiation | |
| RCAN3 | calcium-mediated signaling; anatomical structure morphogenesis | |
| RCBTB2 | - | |
| RCC1 | regulation of S phase of mitotic cell cycle; viral reproduction; spindle assembly; cell division; regulation of mitosis; chromosome segregation; mitotic spindle organization; cell cycle; G1/S transition of mitotic cell cycle | |
| RCE1 | proteolysis | |
| RCN2 | - | |
| RCOR1 | positive regulation of megakaryocyte differentiation; histone H4 deacetylation; erythrocyte differentiation; chromatin modification; blood coagulation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; interspecies interaction between organisms | |
| RCOR2 | negative regulation of transcription, DNA-dependent | |
| RCOR3 | regulation of transcription, DNA-dependent | |
| RCVRN | signal transduction; visual perception; phototransduction; response to stimulus; regulation of calcium ion transport | |
| RDH8 | steroid biosynthetic process; estrogen biosynthetic process; visual perception; retinol metabolic process; response to stimulus | |
| RDM1 | DNA repair; DNA recombination | |
| RDX | microvillus assembly; apical protein localization; actin filament capping | |
| REC8 | sister chromatid cohesion; spermatid development; reciprocal meiotic recombination; synapsis; meiosis; male meiosis I; spermatogenesis; oocyte maturation | |
| RECK | extracellular matrix organization; negative regulation of endopeptidase activity; blood vessel maturation | |
| RECQL | DNA replication; DNA duplex unwinding; DNA strand renaturation; DNA recombination; DNA repair | |
| RECQL5 | DNA duplex unwinding; DNA recombination; DNA repair; DNA metabolic process | |
| REEP4 | - | |
| REG4 | - | |
| REL | cytokine production; regulation of transcription, DNA-dependent; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-12 biosynthetic process; positive regulation of transcription, DNA-dependent | |
| RELL2 | positive regulation of cell-substrate adhesion | |
| RELN | ventral spinal cord development; positive regulation of peptidyl-tyrosine phosphorylation; cell morphogenesis involved in differentiation; neuron migration; proteolysis; cell adhesion; multicellular organismal development; axon guidance; central nervous system development; brain development; locomotory behavior; dendrite development; glial cell differentiation; positive regulation of small GTPase mediated signal transduction; response to pain; positive regulation of protein kinase activity; thyroid hormone metabolic process; reelin-mediated signaling pathway; cerebral cortex tangential migration; spinal cord patterning; peptidyl-tyrosine phosphorylation | |
| RELT | - | |
| REN | kidney development; mesonephros development; angiotensin maturation; regulation of MAPK cascade; renin-angiotensin regulation of aldosterone production; proteolysis; response to stress; regulation of blood pressure; male gonad development; hormone-mediated signaling pathway; response to drug; drinking behavior; cell maturation; response to cAMP; response to cGMP | |
| RENBP | mannose metabolic process; N-acetylglucosamine metabolic process; regulation of blood pressure; negative regulation of endopeptidase activity | |
| REPIN1 | DNA replication | |
| REPS1 | - | |
| RER1 | retrograde vesicle-mediated transport, Golgi to ER | |
| RERE | multicellular organismal development; NLS-bearing substrate import into nucleus; chromatin remodeling | |
| RERG | response to hormone stimulus; GTP catabolic process; negative regulation of cell growth; signal transduction; negative regulation of cell proliferation; small GTPase mediated signal transduction | |
| RERGL | small GTPase mediated signal transduction; signal transduction | |
| REST | negative regulation of calcium ion-dependent exocytosis; cardiac muscle cell myoblast differentiation; negative regulation of insulin secretion; negative regulation of neurogenesis; calcium ion transmembrane transport; histone H4 deacetylation; cellular response to electrical stimulus; cellular response to glucocorticoid stimulus; negative regulation of cortisol biosynthetic process; negative regulation of dense core granule biogenesis; negative regulation of mesenchymal stem cell differentiation; negative regulation of amniotic stem cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of cell proliferation; negative regulation of gene expression; negative regulation of aldosterone biosynthetic process; cellular response to drug; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic proc | |
| RET | positive regulation of cell migration; membrane protein proteolysis; positive regulation of cell adhesion mediated by integrin; neuron maturation; positive regulation of transcription, DNA-dependent; response to pain; enteric nervous system development; Peyer's patch morphogenesis; cellular response to retinoic acid; positive regulation of metanephric glomerulus development; lymphocyte migration into lymphoid organs; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; neural crest cell migration; positive regulation of neuron projection development; MAPK cascade; ureteric bud development; embryonic epithelial tube formation; protein phosphorylation; homophilic cell adhesion; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; nervous system development; posterior midgut development; regulation of cell adhesion; neuron cell-cell adhesion | |
| RETNLB | cell proliferation | |
| REV3L | DNA-dependent DNA replication; translesion synthesis; DNA repair; nucleobase-containing compound metabolic process | |
| REXO1 | - | |
| RFC1 | transcription-coupled nucleotide-excision repair; positive regulation of catalytic activity; telomere maintenance via semi-conservative replication; telomere maintenance via telomerase; regulation of transcription, DNA-dependent; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair; DNA repair; DNA strand elongation involved in DNA replication; DNA-dependent DNA replication; telomere maintenance; telomere maintenance via recombination; mitotic cell cycle; S phase of mitotic cell cycle | |
| RFFL | intracellular protein transport; apoptotic process | |
| RFK | riboflavin metabolic process; small molecule metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; riboflavin biosynthetic process | |
| RFPL4B | - | |
| RFT1 | protein N-linked glycosylation via asparagine; post-translational protein modification; dolichol-linked oligosaccharide biosynthetic process; cellular protein metabolic process; carbohydrate transport; transport | |
| RFTN1 | - | |
| RFTN2 | - | |
| RFWD3 | mitotic cell cycle G1/S transition DNA damage checkpoint; protein ubiquitination; response to ionizing radiation; DNA repair | |
| RFX1 | regulation of transcription, DNA-dependent; immune response | |
| RFX3 | ciliary cell motility; positive regulation of type B pancreatic cell development; epithelial cilium movement involved in determination of left/right asymmetry; regulation of insulin secretion; type B pancreatic cell maturation; regulation of transcription, DNA-dependent; multicellular organismal development; cell differentiation; endocrine pancreas development; cilium assembly; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cell maturation | |
| RFX4 | regulation of transcription, DNA-dependent | |
| RFX5 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| RFX6 | multicellular organismal development; type B pancreatic cell differentiation; pancreatic A cell differentiation; pancreatic E cell differentiation; regulation of insulin secretion; positive regulation of transcription, DNA-dependent; glucose homeostasis; endocrine pancreas development; pancreatic D cell differentiation | |
| RFXANK | Ras protein signal transduction; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter | |
| RGAG1 | - | |
| RGCC | regulation of cyclin-dependent protein kinase activity; cell cycle | |
| RGL1 | cellular lipid metabolic process; small molecule metabolic process; small GTPase mediated signal transduction; signal transduction; regulation of small GTPase mediated signal transduction | |
| RGL3 | regulation of small GTPase mediated signal transduction; signal transduction | |
| RGL4 | small GTPase mediated signal transduction | |
| RGN | regulation of calcium-mediated signaling; positive regulation of ATPase activity; cellular calcium ion homeostasis | |
| RGS11 | G-protein coupled receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; negative regulation of signal transduction; intracellular signal transduction; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity | |
| RGS12 | positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; signal transduction | |
| RGS14 | cell division; negative regulation of ERK1 and ERK2 cascade; regulation of G-protein coupled receptor protein signaling pathway; long-term synaptic potentiation; mitosis; visual learning; long-term memory; learning; negative regulation of MAP kinase activity; termination of G-protein coupled receptor signaling pathway; negative regulation of signal transduction; negative regulation of synaptic plasticity; zygote asymmetric cell division; spindle organization; response to oxidative stress; cell cycle; chromosome segregation; positive regulation of GTPase activity; regulation of DNA-dependent transcription in response to stress; positive regulation of neurogenesis; nucleocytoplasmic transport; platelet-derived growth factor receptor signaling pathway | |
| RGS21 | negative regulation of signal transduction; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity | |
| RGS22 | negative regulation of signal transduction; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity | |
| RGS3 | positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway; negative regulation of signal transduction; regulation of G-protein coupled receptor protein signaling pathway; inactivation of MAPK activity | |
| RGS6 | negative regulation of signal transduction; regulation of G-protein coupled receptor protein signaling pathway; termination of G-protein coupled receptor signaling pathway; positive regulation of neuron differentiation; positive regulation of GTPase activity; G-protein coupled receptor signaling pathway; intracellular signal transduction | |
| RGS7 | G-protein coupled receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; negative regulation of signal transduction; intracellular signal transduction; positive regulation of GTPase activity; termination of G-protein coupled receptor signaling pathway | |
| RGS9 | negative regulation of signal transduction; intracellular signal transduction; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; response to estrogen stimulus; response to stimulus; regulation of G-protein coupled receptor protein signaling pathway; visual perception; nervous system development; dopamine receptor signaling pathway | |
| RHAG | cellular ion homeostasis; ammonium transmembrane transport; transmembrane transport; ammonium transport; carbon dioxide transport | |
| RHBDD1 | proteolysis | |
| RHBDD3 | - | |
| RHBDL2 | proteolysis | |
| RHBG | ammonium transmembrane transport; transepithelial ammonium transport; transmembrane transport; ammonium transport | |
| RHCG | homeostatic process; cellular ion homeostasis; regulation of pH; ammonium transport; amine transport; transmembrane transport; transepithelial ammonium transport; ammonium transmembrane transport; epithelial cell differentiation | |
| RHO | protein phosphorylation; G-protein coupled receptor signaling pathway; visual perception; phototransduction, visible light; rhodopsin mediated phototransduction; rhodopsin mediated signaling pathway; protein-chromophore linkage; response to stimulus; retina development in camera-type eye; cellular response to light stimulus | |
| RHOA | apical junction assembly; phosphatidylinositol-mediated signaling; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB import into nucleus; regulation of osteoblast proliferation; negative regulation of intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; regulation of cell migration; platelet activation; cell differentiation; actin cytoskeleton organization; blood coagulation; skeletal muscle tissue development; axon guidance; Rho protein signal transduction; small GTPase mediated signal transduction; cell-matrix adhesion; cell adhesion; cell cycle; regulation of transcription from RNA polymerase II promoter; GTP catabolic process; cell morphogenesis; regulation of axonogenesis; positive regulation of cell cycle cytokinesis; spindle assembly involved in mitosis; trabecula morphogenesis; positive regulation of stress fiber assembly; cell division; regulation of small GTPase mediated signal transduction; positive regulation of axo | |
| RHOB | regulation of small GTPase mediated signal transduction; negative regulation of cell cycle; cellular response to hydrogen peroxide; cellular response to ionizing radiation; small GTPase mediated signal transduction; apoptotic process; endosome to lysosome transport; protein transport; cell differentiation; platelet activation; cell cycle cytokinesis; blood coagulation; positive regulation of apoptotic process; positive regulation of angiogenesis; axon guidance; multicellular organismal development; Rho protein signal transduction; cell adhesion; transformed cell apoptosis; GTP catabolic process | |
| RHOBTB1 | small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction | |
| RHOBTB2 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction | |
| RHOBTB3 | ATP catabolic process; transport; small GTPase mediated signal transduction; retrograde transport, endosome to Golgi | |
| RHOG | platelet activation; positive regulation of cell proliferation; blood coagulation; axon guidance; Rho protein signal transduction; activation of Rac GTPase activity; small GTPase mediated signal transduction; positive regulation of transcription, DNA-dependent; regulation of small GTPase mediated signal transduction; cell chemotaxis; positive regulation of establishment of protein localization in plasma membrane; actin cytoskeleton organization; Rac protein signal transduction; GTP catabolic process | |
| RHOH | small GTPase mediated signal transduction; negative regulation of I-kappaB kinase/NF-kappaB cascade; T cell differentiation; negative regulation of phosphorylation; regulation of transcription, DNA-dependent; regulation of small GTPase mediated signal transduction | |
| RHOT1 | small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; apoptotic process; cellular homeostasis; mitochondrion transport along microtubule | |
| RHOT2 | regulation of small GTPase mediated signal transduction; mitochondrion transport along microtubule; small GTPase mediated signal transduction; apoptotic process; cellular homeostasis | |
| RIC3 | - | |
| RIC8A | visual learning; response to light stimulus; in utero embryonic development | |
| RIC8B | regulation of G-protein coupled receptor protein signaling pathway | |
| RICTOR | positive regulation of actin filament polymerization; regulation of protein kinase B signaling cascade; embryo development; fibroblast growth factor receptor signaling pathway; actin cytoskeleton reorganization; positive regulation of TOR signaling cascade; regulation of Rac GTPase activity; regulation of actin cytoskeleton organization; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; epidermal growth factor receptor signaling pathway; positive regulation of peptidyl-tyrosine phosphorylation; T cell costimulation | |
| RIF1 | response to DNA damage stimulus; cell cycle | |
| RILP | protein transport; endosome to lysosome transport | |
| RILPL2 | - | |
| RIMBP2 | negative regulation of phosphatase activity | |
| RIMKLA | protein modification process | |
| RIMKLB | protein modification process | |
| RIMS2 | intracellular protein transport | |
| RIMS3 | calcium ion-dependent exocytosis; neurotransmitter transport | |
| RIN1 | signal transduction; endocytosis | |
| RIN3 | endocytosis; signal transduction | |
| RINL | - | |
| RINT1 | G2/M transition DNA damage checkpoint; vesicle-mediated transport; protein transport; cell cycle | |
| RIOK1 | - | |
| RIOK2 | protein phosphorylation | |
| RIOK3 | protein phosphorylation; chromosome segregation | |
| RIPK2 | nucleotide-binding oligomerization domain containing signaling pathway; nucleotide-binding oligomerization domain containing 1 signaling pathway; cellular response to lipoteichoic acid; nucleotide-binding oligomerization domain containing 2 signaling pathway; response to interleukin-1; response to interleukin-12; response to interleukin-18; positive regulation of cytokine-mediated signaling pathway; cellular response to peptidoglycan; T cell proliferation; positive regulation of protein ubiquitination; lipopolysaccharide-mediated signaling pathway; positive regulation of chemokine production; positive regulation of interferon-gamma production; positive regulation of interleukin-2 production; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; positive regulation of immature T cell proliferation; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRI | |
| RIPK4 | - | |
| RIT2 | small GTPase mediated signal transduction; signal transduction; GTP catabolic process; synaptic transmission; nerve growth factor receptor signaling pathway | |
| RITA1 | neurogenesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of Notch signaling pathway; nuclear export | |
| RLBP1 | response to stimulus; vitamin A metabolic process; visual perception | |
| RLF | chromosome organization; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; DNA integration; DNA mediated transformation; regulation of transcription, DNA-dependent | |
| RMDN1 | - | |
| RMDN3 | - | |
| RMI1 | DNA replication | |
| RMND1 | - | |
| RMND5A | - | |
| RMND5B | - | |
| RNASE11 | - | |
| RNASE13 | - | |
| RNASE9 | - | |
| RNASEH1 | mitochondrial DNA replication; RNA catabolic process | |
| RNASEH2A | DNA replication; RNA catabolic process | |
| RNASEH2B | RNA catabolic process | |
| RNASEL | type I interferon-mediated signaling pathway; mRNA processing; protein phosphorylation; cytokine-mediated signaling pathway; negative regulation of viral genome replication; defense response to virus | |
| RNASET2 | RNA catabolic process | |
| RND3 | cell adhesion; GTP catabolic process; small GTPase mediated signal transduction; actin cytoskeleton organization | |
| RNF103 | central nervous system development; protein ubiquitination; ER-associated protein catabolic process | |
| RNF111 | multicellular organismal development; positive regulation of transcription, DNA-dependent; protein ubiquitination | |
| RNF113A | - | |
| RNF113B | - | |
| RNF114 | cell differentiation; spermatogenesis; multicellular organismal development | |
| RNF123 | - | |
| RNF13 | protein autoubiquitination | |
| RNF130 | protein ubiquitination; programmed cell death; apoptotic process | |
| RNF133 | - | |
| RNF144B | apoptotic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of anti-apoptosis | |
| RNF145 | - | |
| RNF146 | positive regulation of canonical Wnt receptor signaling pathway; protein autoubiquitination; protein K48-linked ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; Wnt receptor signaling pathway | |
| RNF157 | - | |
| RNF168 | chromatin modification; positive regulation of DNA repair; response to ionizing radiation; double-strand break repair; histone H2A K63-linked ubiquitination | |
| RNF169 | - | |
| RNF17 | spermatogenesis; multicellular organismal development; cell differentiation; spermatid development | |
| RNF182 | protein ubiquitination | |
| RNF19A | protein modification process; microtubule cytoskeleton organization | |
| RNF2 | regulation of transcription, DNA-dependent; gastrulation with mouth forming second; mitotic cell cycle; histone H2A monoubiquitination; histone ubiquitination; anterior/posterior axis specification; negative regulation of transcription from RNA polymerase II promoter | |
| RNF20 | ubiquitin-dependent protein catabolic process; histone monoubiquitination; regulation of transcription, DNA-dependent; protein polyubiquitination; positive regulation of transcription, DNA-dependent; histone H2B ubiquitination; chromatin modification; negative regulation of cell migration | |
| RNF207 | - | |
| RNF212 | - | |
| RNF213 | protein autoubiquitination; protein ubiquitination; ATP catabolic process | |
| RNF214 | - | |
| RNF220 | protein ubiquitination; protein autoubiquitination | |
| RNF24 | - | |
| RNF25 | positive regulation of NF-kappaB transcription factor activity; protein ubiquitination | |
| RNF41 | protein ubiquitination; induction of apoptosis; apoptotic process; protein polyubiquitination; regulation of reactive oxygen species metabolic process | |
| RNF43 | - | |
| RNF44 | - | |
| RNH1 | mRNA catabolic process; regulation of angiogenesis | |
| RNPEP | retina development in camera-type eye; negative regulation of blood pressure; leukotriene biosynthetic process; aging; proteolysis | |
| ROBO2 | positive regulation of axonogenesis; negative regulation of negative chemotaxis; negative regulation of synapse assembly; retinal ganglion cell axon guidance; apoptotic process involved in luteolysis; cellular response to hormone stimulus; cell differentiation; olfactory bulb interneuron development; axon midline choice point recognition; brain development; central nervous system development; axon guidance; multicellular organismal development; homophilic cell adhesion; ureteric bud development; metanephros development | |
| ROBO4 | cell differentiation; regulation of cell migration; multicellular organismal development; angiogenesis | |
| ROCK1 | leukocyte migration; Rho protein signal transduction; axon guidance; negative regulation of angiogenesis; membrane to membrane docking; actin cytoskeleton organization; signal transduction; regulation of cell adhesion; bleb assembly; regulation of actin cytoskeleton organization; intracellular signal transduction; negative regulation of neuron apoptosis; regulation of keratinocyte differentiation; leukocyte tethering or rolling; regulation of stress fiber assembly; regulation of focal adhesion assembly; regulation of establishment of cell polarity; regulation of cell motility; smooth muscle contraction; cellular component disassembly involved in apoptosis; apoptotic process; protein phosphorylation; cytokinesis; leukocyte cell-cell adhesion | |
| ROCK2 | axon guidance; regulation of stress fiber assembly; regulation of cell motility; negative regulation of angiogenesis; regulation of keratinocyte differentiation; regulation of cell adhesion; regulation of actin cytoskeleton organization; intracellular signal transduction; cytokinesis; neural tube closure; smooth muscle contraction; positive regulation of centrosome duplication; centrosome duplication; protein phosphorylation; regulation of focal adhesion assembly; regulation of establishment of cell polarity | |
| ROR1 | transmembrane receptor protein tyrosine kinase signaling pathway | |
| ROR2 | embryonic genitalia morphogenesis; positive regulation of canonical Wnt receptor signaling pathway; negative regulation of canonical Wnt receptor signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway; positive regulation of transcription, DNA-dependent; inner ear morphogenesis; positive regulation of cell migration; negative regulation of cell proliferation; skeletal system development; multicellular organismal development; JNK cascade; Wnt receptor signaling pathway, calcium modulating pathway; transmembrane receptor protein tyrosine kinase signaling pathway; cartilage condensation; somitogenesis; signal transduction; cell differentiation | |
| RORA | cerebellar Purkinje cell differentiation; cGMP metabolic process; positive regulation of transcription from RNA polymerase II promoter; regulation of macrophage activation; intracellular receptor mediated signaling pathway; gene expression; signal transduction; nitric oxide biosynthetic process | |
| RORC | multicellular organismal development; gene expression; intracellular receptor mediated signaling pathway | |
| ROS1 | cell differentiation; regulation of phosphate transport; cell growth; columnar/cuboidal epithelial cell development; protein phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; spermatogenesis; cell proliferation; negative regulation of gene expression; regulation of TOR signaling cascade; regulation of ERK1 and ERK2 cascade | |
| RP1 | visual perception; phototransduction, visible light; cell projection organization; retina morphogenesis in camera-type eye; cellular response to light stimulus; axoneme assembly; intracellular signal transduction; photoreceptor cell outer segment organization; photoreceptor cell development; photoreceptor cell maintenance; retinal rod cell development; retinal cone cell development; response to stimulus | |
| RP1L1 | photoreceptor cell development; cell projection organization; intracellular signal transduction; photoreceptor cell maintenance; response to stimulus | |
| RPA1 | telomere maintenance via semi-conservative replication; DNA replication; hemopoiesis; positive regulation of cell proliferation; meiosis; DNA recombination; double-strand break repair; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; DNA strand elongation involved in DNA replication; DNA-dependent DNA replication; in utero embryonic development; homeostasis of number of cells within a tissue; chromosome organization; DNA recombinase assembly; double-strand break repair via homologous recombination; telomere maintenance; telomere maintenance via recombination; nucleotide-excision repair, DNA damage removal; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint | |
| RPA3 | telomere maintenance; telomere maintenance via recombination; nucleotide-excision repair, DNA damage removal; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; cell cycle checkpoint; double-strand break repair via homologous recombination; DNA recombinase assembly; DNA replication; DNA strand elongation involved in DNA replication; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; nucleotide-excision repair, DNA gap filling; double-strand break repair; DNA recombination; telomere maintenance via semi-conservative replication | |
| RPAP1 | - | |
| RPAP2 | snRNA transcription; dephosphorylation of RNA polymerase II C-terminal domain | |
| RPAP3 | - | |
| RPE | carbohydrate metabolic process; pentose-phosphate shunt; small molecule metabolic process | |
| RPF1 | rRNA processing | |
| RPGR | response to stimulus; cell projection organization; visual perception; intracellular protein transport; cilium assembly | |
| RPGRIP1L | olfactory bulb development; embryonic hindlimb morphogenesis; lateral ventricle development; specification of segmental identity, mandibular segment; cilium assembly; cerebellum development; camera-type eye development; nose development; negative regulation of G-protein coupled receptor protein signaling pathway; pericardium development; neural tube patterning; regulation of smoothened signaling pathway; brain development; specification of segmental identity, maxillary segment; determination of left/right symmetry; liver development; head development; corpus callosum development; in utero embryonic development; embryonic forelimb morphogenesis; limb morphogenesis; kidney development | |
| RPH3A | intracellular protein transport | |
| RPH3AL | positive regulation of protein secretion; regulation of calcium ion-dependent exocytosis; exocytosis; response to drug; intracellular protein transport; negative regulation of G-protein coupled receptor protein signaling pathway; glucose homeostasis | |
| RPIA | carbohydrate metabolic process; ribose phosphate metabolic process; small molecule metabolic process; pentose-phosphate shunt, non-oxidative branch; metabolic process; pentose-phosphate shunt | |
| RPL13A | viral transcription; viral infectious cycle; mRNA metabolic process; cellular protein metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; translational elongation; translational initiation; translation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | |
| RPL21 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cellular protein metabolic process; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; gene expression; SRP-dependent cotranslational protein targeting to membrane; translational termination; translational elongation; translational initiation; translation | |
| RPL37 | mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; translational elongation; translational termination; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; gene expression; viral reproduction; RNA metabolic process; viral infectious cycle; viral transcription; cellular protein metabolic process | |
| RPL37A | translational termination; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; translation; translational initiation; cellular protein metabolic process; viral transcription; translational elongation; SRP-dependent cotranslational protein targeting to membrane; gene expression; viral reproduction; RNA metabolic process; mRNA metabolic process; viral infectious cycle | |
| RPL7 | cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ribosomal large subunit biogenesis; viral transcription; viral infectious cycle; mRNA metabolic process; RNA metabolic process; viral reproduction; SRP-dependent cotranslational protein targeting to membrane; translational termination; translational elongation; translational initiation; translation; rRNA processing; gene expression | |
| RPN1 | SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; protein N-linked glycosylation via asparagine; post-translational protein modification; translation; protein glycosylation; protein modification process; gene expression | |
| RPP30 | tRNA processing | |
| RPP40 | tRNA processing | |
| RPRM | cell cycle arrest; regulation of mitotic cell cycle | |
| RPS15A | RNA metabolic process; positive regulation of cell cycle; cellular protein metabolic process; viral transcription; viral infectious cycle; mRNA metabolic process; viral reproduction; gene expression; response to virus; positive regulation of cell proliferation; SRP-dependent cotranslational protein targeting to membrane; translational termination; translational elongation; translational initiation; translation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | |
| RPS6KA3 | innate immune response; regulation of DNA-dependent transcription in response to stress; positive regulation of cell differentiation; regulation of translation in response to stress; skeletal system development; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; stress-activated MAPK cascade; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; cell cycle; signal transduction; intracellular protein kinase cascade; synaptic transmission; axon guidance; response to stress; central nervous system development; Toll signaling pathway; positive regulation of cell growth; protein phosphorylation; MyD88-independent toll-like receptor signaling pathway; response to lipopolysaccharide; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like recept | |
| RPS6KA4 | positive regulation of histone acetylation; regulation of transcription, DNA-dependent; interleukin-1-mediated signaling pathway; positive regulation of NF-kappaB transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; histone H3-S28 phosphorylation; histone H3-S10 phosphorylation; positive regulation of histone phosphorylation; positive regulation of CREB transcription factor activity; histone phosphorylation; axon guidance; intracellular protein kinase cascade; inflammatory response; response to stress; protein phosphorylation; negative regulation of cytokine production | |
| RPS6KA5 | protein phosphorylation; regulation of transcription, DNA-dependent; response to stress; inflammatory response; MyD88-independent toll-like receptor signaling pathway; epidermal growth factor receptor signaling pathway; intracellular protein kinase cascade; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; positive regulation of histone acetylation; positive regulation of CREB transcription factor activity; negative regulation of cytokine production; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; interleukin-1-mediated signaling pathway; stress-activated MAPK cascade; positive regulation of NF-kappaB transcription factor activity; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; histone phosphorylation; response to external | |
| RPS6KA6 | negative regulation of mesoderm development; protein phosphorylation; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; signal transduction; intracellular protein kinase cascade; synaptic transmission; axon guidance; central nervous system development; negative regulation of embryonic development; negative regulation of ERK1 and ERK2 cascade | |
| RPS6KB2 | phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; protein kinase B signaling cascade; positive regulation of translational initiation; fibroblast growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; protein phosphorylation; translation | |
| RPS6KC1 | signal transduction | |
| RPS6KL1 | - | |
| RPTN | - | |
| RPTOR | positive regulation of endothelial cell proliferation; cell cycle arrest; insulin receptor signaling pathway; regulation of cell size; cell growth; cellular response to nutrient levels; cellular response to amino acid stimulus; positive regulation of protein serine/threonine kinase activity; TOR signaling cascade; positive regulation of TOR signaling cascade; regulation of phosphorylation; positive regulation of transcription from RNA polymerase III promoter | |
| RPUSD3 | pseudouridine synthesis | |
| RPUSD4 | pseudouridine synthesis | |
| RRAD | GTP catabolic process; signal transduction; small GTPase mediated signal transduction; negative regulation of cell growth | |
| RRAGA | cellular protein localization; cell death; virus-host interaction; positive regulation of TOR signaling cascade; apoptotic process; cellular response to amino acid stimulus; interspecies interaction between organisms; positive regulation of cytolysis | |
| RRAGB | positive regulation of TOR signaling cascade; signal transduction; cellular response to amino acid stimulus; cellular protein localization | |
| RRAGD | cellular response to amino acid stimulus; cellular protein localization; positive regulation of TOR signaling cascade | |
| RREB1 | multicellular organismal development; positive regulation of transcription, DNA-dependent; Ras protein signal transduction; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| RRM2B | deoxyribonucleoside diphosphate metabolic process; nucleobase-containing small molecule interconversion; renal system process; DNA replication; mitochondrial DNA replication; negative regulation of apoptotic process; DNA repair; response to oxidative stress; nucleobase-containing small molecule metabolic process; deoxyribonucleoside triphosphate metabolic process; small molecule metabolic process; kidney development; deoxyribonucleotide biosynthetic process | |
| RRNAD1 | - | |
| RRP12 | - | |
| RRP15 | - | |
| RRP8 | regulation of transcription, DNA-dependent; signal transduction by p53 class mediator resulting in induction of apoptosis; chromatin silencing at rDNA; cellular response to glucose starvation; positive regulation of cell cycle arrest; regulation of transcription by glucose; rRNA processing; chromatin modification | |
| RSAD1 | porphyrin-containing compound biosynthetic process | |
| RSAD2 | regulation of ossification; defense response to virus | |
| RSBN1 | - | |
| RSBN1L | - | |
| RSC1A1 | regulation of transcription, DNA-dependent; transport; intestinal absorption; negative regulation of transport | |
| RSF1 | nucleosome positioning; CenH3-containing nucleosome assembly at centromere; negative regulation of DNA binding; transcription initiation, DNA-dependent; chromatin remodeling; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of viral transcription; nucleosome assembly | |
| RSL1D1 | regulation of protein localization; translation | |
| RSPH3 | - | |
| RSPH4A | cilium movement; cilium axoneme assembly | |
| RSPH6A | - | |
| RSPH9 | cilium axoneme assembly; cilium movement | |
| RSPO3 | canonical Wnt receptor signaling pathway; response to stimulus; branching involved in embryonic placenta morphogenesis | |
| RSPRY1 | - | |
| RSRC2 | - | |
| RTEL1 | nucleobase-containing compound metabolic process; DNA repair; regulation of double-strand break repair via homologous recombination; telomere maintenance | |
| RTF1 | regulation of transcription, DNA-dependent; transcription initiation, DNA-dependent; histone modification | |
| RTKN | regulation of anti-apoptosis; Rho protein signal transduction; apoptotic process; signal transduction | |
| RTKN2 | signal transduction; positive regulation of cell proliferation; hemopoiesis | |
| RTN1 | neuron differentiation; signal transduction | |
| RTN4 | negative regulation of anti-apoptosis; olfactory nerve development; cerebral cortex radial glia guided migration; negative regulation of neuron projection regeneration; negative regulation of cell growth; response to activity; regulation of cell migration; aging; axonal fasciculation; apoptotic process; angiogenesis; negative regulation of axon extension; regulation of sensory perception of pain; positive regulation of dopamine secretion; regulation of apoptotic process; negative regulation of neuron differentiation; negative regulation of axonogenesis; oligodendrocyte differentiation; regulation of axonogenesis; endoplasmic reticulum tubular network organization; regulation of branching morphogenesis of a nerve; cardiac epithelial to mesenchymal transition; positive regulation of glial cell differentiation; nerve growth factor receptor signaling pathway; regulation of axon regeneration | |
| RTN4RL2 | axon regeneration | |
| RTP5 | - | |
| RTTN | multicellular organismal development; determination of left/right symmetry | |
| RUBCN | negative regulation of endocytosis; negative regulation of autophagy | |
| RUFY1 | protein transport; endocytosis | |
| RUFY2 | - | |
| RUFY3 | negative regulation of axonogenesis; cell differentiation; nervous system development; multicellular organismal development | |
| RUNX1 | hemopoietic stem cell proliferation; peripheral nervous system neuron development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of angiogenesis; positive regulation of granulocyte differentiation; negative regulation of granulocyte differentiation; myeloid cell differentiation; hemopoiesis | |
| RUNX1T1 | regulation of transcription, DNA-dependent; regulation of DNA binding; fat cell differentiation; generation of precursor metabolites and energy | |
| RUNX3 | regulation of transcription, DNA-dependent; protein phosphorylation; induction of apoptosis; negative regulation of cell cycle; peripheral nervous system neuron development; negative regulation of epithelial cell proliferation; transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter | |
| RUSC1 | - | |
| RUSC2 | - | |
| RUVBL2 | histone H4 acetylation; regulation of growth; cellular response to UV; DNA duplex unwinding; chromatin modification; protein folding; regulation of transcription, DNA-dependent; DNA recombination; DNA repair; ATP catabolic process; histone H2A acetylation | |
| RWDD1 | - | |
| RWDD3 | - | |
| RXFP1 | cell differentiation; nipple morphogenesis; lung connective tissue development; extracellular matrix organization; G-protein coupled receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; parturition | |
| RXFP2 | positive regulation of cAMP biosynthetic process; negative regulation of apoptotic process; signal transduction; male gonad development; oocyte maturation; activation of adenylate cyclase activity by G-protein signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; negative regulation of cell proliferation | |
| RXFP3 | G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger | |
| RXFP4 | - | |
| RXRG | peripheral nervous system development; gene expression; response to organic cyclic compound; heart development; skeletal muscle tissue development; retinoic acid receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cellular response to hormone stimulus; response to retinoic acid; neuron differentiation | |
| RYR1 | calcium ion transmembrane transport; cellular response to caffeine; transmembrane transport; regulation of calcium ion transport via voltage-gated calcium channel activity; cytosolic calcium ion homeostasis; release of sequestered calcium ion into cytosol; skeletal muscle fiber development; ossification involved in bone maturation; skin development; response to caffeine; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; multicellular organismal development; muscle contraction; calcium ion transport; ion transport; outflow tract morphogenesis; response to hypoxia | |
| S100A1 | regulation of heart contraction; negative regulation of transcription from RNA polymerase II promoter; intracellular signal transduction | |
| S100A10 | positive regulation of binding; cellular response to acid; signal transduction | |
| S100A12 | xenobiotic metabolic process; defense response to fungus; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; defense response to bacterium; killing of cells of other organism; inflammatory response | |
| S100A9 | regulation of integrin biosynthetic process; leukocyte chemotaxis; actin cytoskeleton reorganization; response to zinc ion; cell-cell signaling; response to lipopolysaccharide; signal transduction; response to ethanol; inflammatory response; chemotaxis; chronic inflammatory response | |
| S100P | endothelial cell migration; response to organic substance | |
| S1PR1 | positive regulation of smooth muscle cell proliferation; negative regulation of stress fiber assembly; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; positive regulation of positive chemotaxis; positive regulation of transcription from RNA polymerase II promoter; endothelial cell differentiation; positive regulation of Ras GTPase activity; angiogenesis; cell adhesion; G-protein coupled receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; brain development; transmission of nerve impulse; regulation of cell adhesion; neuron differentiation; positive regulation of cell migration | |
| S1PR4 | immune response; G-protein coupled receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; activation of phospholipase C activity; elevation of cytosolic calcium ion concentration | |
| SAAL1 | acute-phase response | |
| SACM1L | dephosphorylation; phosphatidylinositol dephosphorylation | |
| SACS | cell death; negative regulation of inclusion body assembly; protein folding | |
| SAFB | chromatin organization; regulation of transcription, DNA-dependent; intracellular estrogen receptor signaling pathway; growth; hormone metabolic process; positive regulation of transcription from RNA polymerase II promoter | |
| SAFB2 | regulation of transcription, DNA-dependent | |
| SAGE1 | - | |
| SALL2 | neural tube development; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| SALL3 | regulation of transcription, DNA-dependent | |
| SALL4 | negative regulation of transcription from RNA polymerase II promoter; in utero embryonic development; inner cell mass cell proliferation; neural tube closure; ventricular septum development; regulation of transcription, DNA-dependent; heart development; tissue development; neural tube development; embryonic limb morphogenesis; positive regulation of transcription from RNA polymerase II promoter | |
| SAMD11 | - | |
| SAMD12 | - | |
| SAMD15 | - | |
| SAMD3 | - | |
| SAMD4A | negative regulation of translation; positive regulation of translation | |
| SAMD7 | - | |
| SAMD8 | sphingomyelin biosynthetic process; sphingolipid metabolic process; lipid metabolic process | |
| SAMD9 | - | |
| SAMD9L | - | |
| SAMHD1 | immune response; regulation of innate immune response; defense response to virus | |
| SAMM50 | protein import into mitochondrial outer membrane | |
| SAP130 | histone H3 acetylation; regulation of transcription, DNA-dependent | |
| SAP18 | regulation of transcription from RNA polymerase II promoter | |
| SAP30BP | induction of apoptosis; apoptotic process; regulation of transcription, DNA-dependent | |
| SAPCD2 | - | |
| SARAF | - | |
| SARDH | glycine catabolic process | |
| SARS2 | gene expression; seryl-tRNA aminoacylation; tRNA aminoacylation for protein translation | |
| SASH1 | - | |
| SASH3 | positive regulation of immunoglobulin production; positive regulation of lymphocyte activation; positive regulation of T cell cytokine production; positive regulation of adaptive immune response; positive regulation of B cell proliferation; positive regulation of interferon-gamma production; positive regulation of interleukin-10 production; positive regulation of interleukin-2 production; positive regulation of interleukin-4 production; positive regulation of tumor necrosis factor production; positive regulation of T cell proliferation; positive regulation of CD4-positive, alpha-beta T cell differentiation; positive regulation of organ growth; homeostasis of number of cells within a tissue | |
| SASS6 | centrosome duplication; centriole replication; cell cycle | |
| SAT2 | - | |
| SATB1 | negative regulation of transcription from RNA polymerase II promoter; chromatin organization; apoptotic process; cellular component disassembly involved in apoptosis; chromatin modification; interspecies interaction between organisms | |
| SATB2 | palate development; negative regulation of transcription from RNA polymerase II promoter; neuron migration; osteoblast development; chromatin remodeling; cartilage development; multicellular organismal development; embryonic pattern specification; embryonic skeletal system morphogenesis; positive regulation of transcription from RNA polymerase II promoter | |
| SATL1 | - | |
| SAV1 | lung epithelial cell differentiation; positive regulation of apoptotic process; hippo signaling cascade; hair follicle development; signal transduction; regulation of stem cell maintenance; keratinocyte differentiation; regulation of organ growth; negative regulation of epithelial cell proliferation; intestinal epithelial cell differentiation; negative regulation of cardiac muscle cell proliferation; ventricular septum morphogenesis | |
| SAXO1 | - | |
| SBF1 | protein dephosphorylation | |
| SBF2 | myelination; protein tetramerization; regulation of catalytic activity | |
| SBK1 | peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; brain development | |
| SBNO1 | - | |
| SCAF1 | transcription from RNA polymerase II promoter; mRNA processing; RNA splicing | |
| SCAF11 | spliceosome assembly; RNA splicing, via transesterification reactions; RNA splicing; mRNA processing | |
| SCAF4 | mRNA processing | |
| SCAF8 | transcription from RNA polymerase II promoter; RNA splicing; mRNA processing | |
| SCAI | regulation of transcription, DNA-dependent; negative regulation of Rho protein signal transduction; negative regulation of cell migration; negative regulation of signal transduction | |
| SCAMP2 | post-Golgi vesicle-mediated transport; protein transport | |
| SCAP | response to hypoxia; positive regulation of low-density lipoprotein particle receptor biosynthetic process; negative regulation of cholesterol biosynthetic process; regulation of fatty acid biosynthetic process; response to insulin stimulus; cholesterol metabolic process; positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway; steroid metabolic process; aging | |
| SCARA3 | response to oxidative stress; UV protection | |
| SCARA5 | endocytosis; protein homotrimerization; iron ion transmembrane transport; cellular response to heat; ion transport; cellular iron ion homeostasis | |
| SCARB1 | endothelial cell proliferation; lipid metabolic process; androgen biosynthetic process; blood vessel endothelial cell migration; cholesterol catabolic process; cholesterol homeostasis; lipoprotein metabolic process; wound healing; high-density lipoprotein particle clearance; low-density lipoprotein particle clearance; recognition of apoptotic cell; high-density lipoprotein particle remodeling; transport; cell adhesion; positive regulation of endothelial cell migration; positive regulation of triglyceride biosynthetic process; positive regulation of cholesterol storage; regulation of phosphatidylcholine catabolic process; phospholipid transport; lipopolysaccharide transport; lipopolysaccharide-mediated signaling pathway; detection of lipopolysaccharide; cholesterol efflux; small molecule metabolic process; interspecies interaction between organisms; regulation of phagocytosis; positive regulation of nitric-oxide synthase activity; adhesion to symbiont; triglyceride homeostasis; cholesterol import; reverse chol | |
| SCARB2 | protein targeting to lysosome; cell adhesion | |
| SCARF1 | cholesterol catabolic process; receptor-mediated endocytosis; cell adhesion; positive regulation of neuron projection development; neuron remodeling; dendrite development; positive regulation of axon regeneration | |
| SCD5 | oxidation-reduction process; fatty acid biosynthetic process | |
| SCEL | epidermis development; embryo development; keratinocyte differentiation | |
| SCFD1 | response to hypoxia; regulation of ER to Golgi vesicle-mediated transport; vesicle-mediated transport; protein transport; response to toxin; vesicle docking involved in exocytosis; post-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER | |
| SCG2 | endothelial cell migration; negative regulation of apoptotic process; intracellular signal transduction; protein secretion; eosinophil chemotaxis; inflammatory response; cellular component movement; positive regulation of endothelial cell proliferation; negative regulation of endothelial cell proliferation; angiogenesis; MAPK cascade; positive chemotaxis; induction of positive chemotaxis | |
| SCG3 | platelet degranulation; blood coagulation; platelet activation | |
| SCGB1D1 | - | |
| SCGB2A2 | - | |
| SCLT1 | clustering of voltage-gated sodium channels | |
| SCMH1 | regulation of transcription, DNA-dependent; multicellular organismal development; anatomical structure morphogenesis; gene silencing; negative regulation of transcription, DNA-dependent | |
| SCML2 | anatomical structure morphogenesis; regulation of transcription, DNA-dependent | |
| SCN10A | ion transport; transmembrane transport; sensory perception; sodium ion transport | |
| SCN11A | ion transport; sodium ion transport; response to drug; transmembrane transport | |
| SCN1A | ion transport; sodium ion transport; adult walking behavior; transmembrane transport; neuromuscular process controlling posture; neuronal action potential propagation; regulation of action potential in neuron | |
| SCN2A | ion transport; sodium ion transport; apoptotic process; nervous system development; myelination; transmembrane transport | |
| SCN3A | ion transport; sodium ion transport; transmembrane transport | |
| SCN3B | axon guidance; positive regulation of action potential; membrane depolarization; positive regulation of sodium ion transport via voltage-gated sodium channel activity; sensory perception of pain; ion transport; sodium ion transport; nervous system development | |
| SCN4B | sodium ion transport; positive regulation of sodium ion transport via voltage-gated sodium channel activity; ion transport | |
| SCNN1B | sensory perception of taste; response to stimulus; wound healing, spreading of epidermal cells; excretion; response to hypoxia; sodium ion transport; ion transport; regulation of sodium ion transport | |
| SCNN1G | response to hypoxia; sensory perception of taste; response to stimulus; sodium ion transmembrane transport; wound healing, spreading of epidermal cells; excretion; sodium ion transport; ion transport | |
| SCO2 | cellular copper ion homeostasis; oxidation-reduction process; respiratory electron transport chain; response to activity; respiratory chain complex IV assembly; muscle system process; in utero embryonic development; copper ion transport | |
| SCOC | - | |
| SCP2 | cellular lipid metabolic process; small molecule metabolic process; bile acid biosynthetic process; transport; lipid transport; peroxisome organization; bile acid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase | |
| SCPEP1 | retinoic acid metabolic process; proteolysis | |
| SCRIB | cell migration; positive chemotaxis; cell proliferation; negative regulation of mitotic cell cycle; cell-cell adhesion; mammary gland duct morphogenesis; interspecies interaction between organisms; positive regulation of apoptotic process; establishment of apical/basal cell polarity; activation of Rac GTPase activity; apoptosis involved in morphogenesis; cell differentiation; positive regulation of receptor recycling; neural tube closure; protein localization to adherens junction; multicellular organismal development | |
| SCRN1 | proteolysis; exocytosis | |
| SCRN2 | proteolysis | |
| SCRN3 | proteolysis | |
| SCRT1 | regulation of transcription, DNA-dependent | |
| SCRT2 | regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; anti-apoptosis | |
| SCUBE1 | blood coagulation; inflammatory response; adult heart development; post-embryonic development; endothelial cell differentiation; protein homooligomerization | |
| SCUBE2 | - | |
| SCUBE3 | protein heterooligomerization; protein homooligomerization | |
| SCYL2 | positive regulation of clathrin-mediated endocytosis; negative regulation of canonical Wnt receptor signaling pathway; endosome to lysosome transport; positive regulation of receptor internalization | |
| SCYL3 | cell migration | |
| SDAD1 | protein transport; ribosomal large subunit biogenesis | |
| SDC3 | cell adhesion | |
| SDCBP | positive regulation of JNK cascade; positive regulation of phosphorylation; intracellular signal transduction; actin cytoskeleton organization; axon guidance; Ras protein signal transduction; substrate-dependent cell migration, cell extension; protein targeting to membrane; synaptic transmission | |
| SDCBP2 | intracellular transport; nervous system development; intracellular signal transduction | |
| SDCCAG8 | tube formation; establishment of cell polarity; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| SDE2 | - | |
| SDF2 | protein glycosylation | |
| SDHAF2 | protein-FAD linkage; mitochondrial electron transport, succinate to ubiquinone | |
| SDK1 | cell adhesion | |
| SDPR | - | |
| SDR16C5 | keratinocyte proliferation; retinal metabolic process; retinol metabolic process; detection of light stimulus involved in visual perception | |
| SDR9C7 | - | |
| SDSL | cellular amino acid metabolic process | |
| SEC13 | mitotic prometaphase; cellular protein metabolic process; vesicle-mediated transport; cellular membrane organization; ER to Golgi vesicle-mediated transport; intracellular protein transport; antigen processing and presentation of peptide antigen via MHC class I; mitotic cell cycle; protein N-linked glycosylation via asparagine; M phase of mitotic cell cycle; post-translational protein modification; COPII vesicle coating; mRNA transport | |
| SEC14L1 | transport | |
| SEC14L4 | - | |
| SEC22A | vesicle-mediated transport; protein transport; ER to Golgi vesicle-mediated transport | |
| SEC23A | post-translational protein modification; cellular protein metabolic process; COPII vesicle coating; protein N-linked glycosylation via asparagine; vesicle-mediated transport; cellular membrane organization; antigen processing and presentation of peptide antigen via MHC class I; intracellular protein transport; ER to Golgi vesicle-mediated transport | |
| SEC23B | intracellular protein transport; vesicle-mediated transport; ER to Golgi vesicle-mediated transport | |
| SEC23IP | Golgi organization; intracellular protein transport | |
| SEC24A | cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; cellular membrane organization; ER to Golgi vesicle-mediated transport; intracellular protein transport; antigen processing and presentation of peptide antigen via MHC class I; vesicle-mediated transport; COPII vesicle coating | |
| SEC24B | COPII vesicle coating; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; vesicle-mediated transport; cellular membrane organization; ER to Golgi vesicle-mediated transport; intracellular protein transport; antigen processing and presentation of peptide antigen via MHC class I | |
| SEC24C | COPII vesicle coating; antigen processing and presentation of peptide antigen via MHC class I; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; vesicle-mediated transport; cellular membrane organization; ER to Golgi vesicle-mediated transport; intracellular protein transport | |
| SEC24D | COPII vesicle coating; cellular protein metabolic process; post-translational protein modification; vesicle-mediated transport; cellular membrane organization; ER to Golgi vesicle-mediated transport; intracellular protein transport; antigen processing and presentation of peptide antigen via MHC class I; protein N-linked glycosylation via asparagine | |
| SEC31A | endoplasmic reticulum unfolded protein response; antigen processing and presentation of peptide antigen via MHC class I; response to calcium ion; ER to Golgi vesicle-mediated transport; protein transport; cellular membrane organization; vesicle-mediated transport; protein N-linked glycosylation via asparagine; COPII vesicle coating; post-translational protein modification; activation of signaling protein activity involved in unfolded protein response; cellular protein metabolic process | |
| SEC31B | protein transport; vesicle-mediated transport | |
| SEC61A1 | antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; protein transport; response to interferon-gamma; antigen processing and presentation of exogenous peptide antigen via MHC class I; protein targeting to ER | |
| SEC61A2 | protein transport; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I | |
| SEC62 | cotranslational protein targeting to membrane | |
| SECISBP2 | translation | |
| SECISBP2L | - | |
| SEH1L | attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; protein transport; glucose transport; cytokine-mediated signaling pathway; viral reproduction; mitotic prometaphase; transmembrane transport; regulation of glucose transport; hexose transport; M phase of mitotic cell cycle; mitotic cell cycle; carbohydrate metabolic process; nuclear pore organization; chromosome segregation; small molecule metabolic process; mRNA transport; cell division; mitotic metaphase plate congression | |
| SEL1L | Notch signaling pathway | |
| SEL1L2 | - | |
| SELE | positive regulation of receptor internalization; response to lipopolysaccharide; response to tumor necrosis factor; regulation of inflammatory response; leukocyte tethering or rolling; response to interleukin-1; actin filament-based process; calcium-mediated signaling; activation of phospholipase C activity; leukocyte cell-cell adhesion; heterophilic cell-cell adhesion; cell adhesion; inflammatory response; positive regulation of leukocyte migration; leukocyte migration involved in inflammatory response | |
| SELENBP1 | protein transport | |
| SELP | response to organic cyclic compound; leukocyte tethering or rolling; leukocyte migration; defense response to Gram-negative bacterium; blood vessel morphogenesis; positive regulation of cell adhesion; response to lipopolysaccharide; platelet activation; positive regulation of platelet activation; blood coagulation; leukocyte cell-cell adhesion; heterophilic cell-cell adhesion; cell adhesion; inflammatory response; regulation of cellular extravasation; positive regulation of leukocyte migration; platelet degranulation | |
| SELPLG | leukocyte migration; cell adhesion; blood coagulation; cellular response to interleukin-6; leukocyte tethering or rolling | |
| SEMA3C | neural crest cell migration; heart development; limb bud formation; dichotomous subdivision of terminal units involved in salivary gland branching; post-embryonic development; neural tube development; response to drug; axon guidance; immune response; somitogenesis; cardiac right ventricle morphogenesis; pulmonary myocardium development; outflow tract morphogenesis; blood vessel remodeling | |
| SEMA3D | cell differentiation; nervous system development; multicellular organismal development | |
| SEMA3E | synapse organization; negative regulation of cell-matrix adhesion; semaphorin-plexin signaling pathway; regulation of actin cytoskeleton reorganization; regulation of cell shape; negative regulation of angiogenesis; patterning of blood vessels; axon guidance; nervous system development; sprouting angiogenesis; multicellular organismal development; cell differentiation | |
| SEMA3F | neural crest cell migration; multicellular organismal development; axon guidance; negative regulation of axon extension involved in axon guidance; negative chemotaxis | |
| SEMA3G | multicellular organismal development | |
| SEMA4A | cell differentiation; axon guidance; nervous system development; multicellular organismal development | |
| SEMA4C | muscle cell differentiation; neural tube closure; multicellular organismal development; nervous system development; cell migration in hindbrain; positive regulation of stress-activated MAPK cascade; semaphorin-plexin signaling pathway | |
| SEMA4D | leukocyte aggregation; regulation of cell shape; negative regulation of alkaline phosphatase activity; positive regulation of phosphatidylinositol 3-kinase cascade; cell differentiation; positive regulation of cell migration; regulation of cell projection organization; positive regulation of Rho GTPase activity; ossification involved in bone maturation; semaphorin-plexin signaling pathway; positive regulation of collateral sprouting; trabecula morphogenesis; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of osteoblast differentiation; multicellular organismal development; regulation of dendrite morphogenesis; positive regulation of protein phosphorylation; nervous system development; axon guidance; anti-apoptosis; immune response; cell adhesion | |
| SEMA5A | cell-cell signaling; cell adhesion; patterning of blood vessels; cell differentiation; axon guidance; nervous system development; multicellular organismal development; signal transduction | |
| SEMA5B | nervous system development; cell differentiation; multicellular organismal development | |
| SEMA6B | multicellular organismal development; nervous system development; cell differentiation | |
| SEMA6D | multicellular organismal development; cell differentiation; axon guidance; nervous system development | |
| SEMA7A | cell differentiation; positive regulation of ERK1 and ERK2 cascade; positive regulation of macrophage cytokine production; regulation of inflammatory response; positive regulation of axon extension; axon guidance; nervous system development; multicellular organismal development; integrin-mediated signaling pathway; immune response | |
| SEMG1 | sexual reproduction; insemination | |
| SEMG2 | sexual reproduction | |
| SENP2 | negative regulation of protein binding; positive regulation of protein phosphorylation; dorsal/ventral axis specification; proteolysis; regulation of Wnt receptor signaling pathway; protein transport; protein desumoylation; regulation of protein metabolic process; mRNA transport | |
| SENP6 | proteolysis; protein desumoylation; protein modification by small protein removal; regulation of spindle assembly; regulation of kinetochore assembly | |
| SENP7 | proteolysis | |
| SENP8 | proteolysis | |
| SEPHS1 | protein modification process | |
| SEPSECS | translation; oxidation-reduction process; selenocysteine incorporation | |
| SEPT1 | cell division; cell cycle | |
| SEPT10 | cell division; cell cycle | |
| SEPT11 | cell cycle; cell division; protein heterooligomerization | |
| SEPT3 | cytokinesis; cell cycle | |
| SEPT4 | cell cycle; apoptotic process; brain development; sperm capacitation; positive regulation of intrinsic apoptotic signaling pathway; cytokinesis; GTP catabolic process; sperm mitochondrion organization; positive regulation of protein ubiquitination; regulation of apoptotic process; positive regulation of apoptotic process | |
| SEPT5 | synaptic vesicle targeting; cell cycle; GTP catabolic process; cytokinesis; regulation of exocytosis | |
| SEPT6 | cytokinesis; interspecies interaction between organisms; cell cycle | |
| SEPT8 | cell cycle | |
| SERAC1 | extracellular matrix organization; intracellular protein transport; GPI anchor metabolic process | |
| SERGEF | negative regulation of protein secretion; signal transduction | |
| SERINC1 | phosphatidylserine metabolic process; positive regulation of transferase activity; L-serine transport; phospholipid biosynthetic process; sphingolipid metabolic process; lipid metabolic process | |
| SERINC3 | induction of apoptosis | |
| SERINC4 | lipid metabolic process; phospholipid biosynthetic process | |
| SERPINA1 | negative regulation of endopeptidase activity; acute-phase response; inflammatory response; blood coagulation; response to lead ion; response to estradiol stimulus; response to organic cyclic compound; regulation of proteolysis; platelet activation; response to lipopolysaccharide; response to methanol; response to triglyceride; response to cytokine stimulus; response to chromate; platelet degranulation; response to hypoxia | |
| SERPINA10 | regulation of acrosome reaction; negative regulation of endopeptidase activity; tissue regeneration; regulation of proteolysis | |
| SERPINA3 | maintenance of gastrointestinal epithelium; regulation of proteolysis; regulation of lipid metabolic process; negative regulation of endopeptidase activity; acute-phase response; inflammatory response | |
| SERPINA4 | negative regulation of endopeptidase activity; regulation of proteolysis | |
| SERPINA5 | regulation of proteolysis; negative regulation of endopeptidase activity; fusion of sperm to egg plasma membrane; spermatogenesis; lipid transport; transport | |
| SERPINA6 | regulation of proteolysis; negative regulation of endopeptidase activity; glucocorticoid metabolic process; transport | |
| SERPINA7 | response to prostaglandin E stimulus; response to steroid hormone stimulus; response to corticosterone stimulus; aging; post-embryonic development; response to vitamin A; regulation of proteolysis; response to drug; response to nutrient levels; response to peptide hormone stimulus; negative regulation of endopeptidase activity | |
| SERPINB10 | negative regulation of proteolysis; regulation of proteolysis; negative regulation of endopeptidase activity | |
| SERPINB12 | regulation of proteolysis; negative regulation of endopeptidase activity; negative regulation of protein catabolic process | |
| SERPINB13 | response to UV; negative regulation of endopeptidase activity; regulation of proteolysis | |
| SERPINB2 | blood coagulation; regulation of proteolysis; negative regulation of endopeptidase activity; anti-apoptosis; fibrinolysis | |
| SERPINB6 | negative regulation of endopeptidase activity; regulation of proteolysis | |
| SERPINB7 | regulation of proteolysis; negative regulation of endopeptidase activity | |
| SERPINB8 | negative regulation of endopeptidase activity; regulation of proteolysis | |
| SERPINB9 | anti-apoptosis; immune response; negative regulation of endopeptidase activity; regulation of proteolysis; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to estrogen stimulus; mast cell mediated immunity | |
| SERPINE1 | cellular response to chemical stimulus; response to cytokine stimulus; positive regulation of leukotriene production involved in inflammatory response; fibrinolysis; negative regulation of cell adhesion mediated by integrin; tissue regeneration; response to estrogen stimulus; negative regulation of apoptotic process; glucose homeostasis; positive regulation of angiogenesis; positive regulation of receptor-mediated endocytosis; positive regulation of inflammatory response; negative regulation of smooth muscle cell-matrix adhesion; positive regulation of monocyte chemotaxis; cellular response to gravity; cellular response to lipopolysaccharide; defense response to Gram-negative bacterium; response to glucocorticoid stimulus; negative regulation of fibrinolysis; response to hyperoxia; negative regulation of vascular wound healing; negative regulation of wound healing; negative regulation of cell migration; positive regulation of interleukin-8 production; response to reactive oxygen species; chronological cell ag | |
| SERPINE2 | negative regulation of endopeptidase activity; negative regulation of platelet aggregation; positive regulation of astrocyte differentiation; negative regulation of proteolysis; regulation of cell migration; negative regulation of blood coagulation; cell differentiation; negative regulation of protein processing; nervous system development; multicellular organismal development; negative regulation of plasminogen activation | |
| SERPINF1 | regulation of proteolysis; negative regulation of epithelial cell proliferation involved in prostate gland development; positive regulation of neurogenesis; kidney development; multicellular organismal development; aging; short-term memory; cell proliferation; negative regulation of endopeptidase activity; negative regulation of angiogenesis; response to retinoic acid; negative regulation of inflammatory response; response to glucocorticoid stimulus | |
| SERPING1 | platelet degranulation; negative regulation of complement activation, lectin pathway; complement activation, classical pathway; blood coagulation; blood coagulation, intrinsic pathway; blood circulation; negative regulation of endopeptidase activity; platelet activation; innate immune response | |
| SERPINH1 | response to stress; response to unfolded protein; negative regulation of endopeptidase activity; regulation of proteolysis | |
| SERPINI1 | peripheral nervous system development; regulation of proteolysis; regulation of cell adhesion; negative regulation of endopeptidase activity; central nervous system development | |
| SERPINI2 | regulation of proteolysis; negative regulation of endopeptidase activity; cellular component movement | |
| SERTAD1 | positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; regulation of cyclin-dependent protein kinase activity | |
| SERTAD4 | - | |
| SESN1 | response to DNA damage stimulus; cell cycle arrest; negative regulation of cell proliferation | |
| SESN2 | cell cycle arrest | |
| SESN3 | cell cycle arrest | |
| SESTD1 | regulation of calcium ion transport via voltage-gated calcium channel activity | |
| SETBP1 | - | |
| SETD1A | regulation of transcription, DNA-dependent; chromatin modification; histone H3-K4 methylation | |
| SETD2 | embryonic placenta morphogenesis; forebrain development; cell migration involved in vasculogenesis; mesoderm morphogenesis; embryonic organ development; embryonic cranial skeleton morphogenesis; stem cell development; pericardium development; peptidyl-lysine trimethylation; chromatin modification; histone H3-K36 methylation; coronary vasculature morphogenesis; morphogenesis of a branching structure; neural tube closure; regulation of transcription, DNA-dependent; angiogenesis | |
| SETD3 | chromatin modification; histone H3-K36 methylation; peptidyl-lysine trimethylation; peptidyl-lysine monomethylation; peptidyl-lysine dimethylation; positive regulation of transcription, DNA-dependent | |
| SETD6 | peptidyl-lysine monomethylation; negative regulation of NF-kappaB transcription factor activity; regulation of inflammatory response | |
| SETDB1 | chromatin modification; regulation of transcription, DNA-dependent | |
| SETDB2 | left/right axis specification; mitosis; multicellular organismal development; chromatin modification; negative regulation of transcription, DNA-dependent; histone H3-K9 methylation; chromosome segregation; cell division; cell cycle; heart looping | |
| SETMAR | transposition, DNA-mediated; DNA repair; DNA catabolic process, endonucleolytic; DNA double-strand break processing; DNA integration; negative regulation of chromosome organization; positive regulation of double-strand break repair via nonhomologous end joining; negative regulation of cell cycle arrest; chromatin modification | |
| SETX | double-strand break repair; RNA processing; cell death; DNA duplex unwinding | |
| SEZ6L | - | |
| SEZ6L2 | - | |
| SF1 | spliceosome assembly; nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; RNA splicing | |
| SF3A1 | RNA splicing; gene expression; nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; mRNA processing | |
| SF3A2 | gene expression; RNA splicing; mRNA processing; nuclear mRNA splicing, via spliceosome; nuclear mRNA 3'-splice site recognition | |
| SF3B1 | anterior/posterior pattern specification; RNA splicing; nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; gene expression | |
| SF3B2 | interspecies interaction between organisms; gene expression; RNA splicing; mRNA processing; nuclear mRNA splicing, via spliceosome | |
| SF3B3 | RNA splicing; gene expression; mRNA processing; nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; protein complex assembly | |
| SFI1 | negative regulation of phosphatase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| SFN | regulation of cyclin-dependent protein kinase activity; keratinocyte proliferation; skin development; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of protein export from nucleus; positive regulation of cell growth; keratinocyte differentiation; DNA damage response, signal transduction resulting in induction of apoptosis; negative regulation of cell proliferation; cell proliferation; signal transduction; apoptotic process; negative regulation of protein kinase activity; release of cytochrome c from mitochondria | |
| SFPQ | alternative nuclear mRNA splicing, via spliceosome; RNA splicing; mRNA processing; regulation of transcription, DNA-dependent; DNA recombination; DNA repair | |
| SFRP1 | response to organic cyclic compound; positive regulation of Wnt receptor signaling pathway; neural tube development; dorsal/ventral axis specification; menstrual cycle phase; neural crest cell fate commitment; negative regulation of epithelial to mesenchymal transition; negative regulation of gene expression; regulation of cell cycle process; positive regulation of cell proliferation; osteoblast differentiation; ureteric bud development; neural tube closure; vasculature development; positive regulation of cell-matrix adhesion; hemopoietic progenitor cell differentiation; DNA fragmentation involved in apoptotic nuclear change; brain development; negative regulation of Wnt receptor signaling pathway; negative regulation of cell proliferation; gonad development; negative regulation of ossification; male gonad development; female gonad development; cellular response to starvation; embryo development; cellular response to transforming growth factor beta stimulus; hemopoietic stem cell differentiation; bone trabecu | |
| SFRP2 | negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of epithelial cell proliferation; digestive tract morphogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of anti-apoptosis; positive regulation of angiogenesis; positive regulation of osteoblast differentiation; positive regulation of fat cell differentiation; negative regulation of JUN kinase activity; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; positive regulation of apoptotic process; embryonic digit morphogenesis; negative regulation of mesodermal cell fate specification; positive regulation of cell growth; cartilage development; convergent extension involved in axis elongation; bone morphogenesis; sclerotome development; negative regulation of dermatome development; hemopoietic stem cell proliferation; cellular response to X-ray; negative | |
| SFSWAP | regulation of transcription, DNA-dependent; mRNA splice site selection; mRNA processing; RNA splicing; negative regulation of nuclear mRNA splicing, via spliceosome | |
| SFT2D2 | protein transport; vesicle-mediated transport | |
| SFTPB | response to lipopolysaccharide; response to vitamin A; cellular response to mechanical stimulus; response to epidermal growth factor stimulus; organ morphogenesis; response to glucose stimulus; circadian rhythm; response to interleukin-6; response to hyperoxia; response to glucocorticoid stimulus; respiratory gaseous exchange; cellular response to nitric oxide; lipid metabolic process; sphingolipid metabolic process; response to hypoxia | |
| SFTPC | cellular response to nitric oxide; response to hormone stimulus; response to glucocorticoid stimulus; circadian rhythm; respiratory gaseous exchange; protein homooligomerization; cellular response to mechanical stimulus; response to growth factor stimulus; response to retinoic acid; response to lipopolysaccharide; response to glucose stimulus; response to interleukin-6; response to hyperoxia; response to cAMP | |
| SFTPD | macrophage chemotaxis; negative regulation of interleukin-2 biosynthetic process; lung alveolus development; positive regulation of phagocytosis; reactive oxygen species metabolic process; surfactant homeostasis; innate immune response; negative regulation of T cell proliferation; respiratory gaseous exchange; receptor-mediated endocytosis; regulation of cytokine production | |
| SFXN1 | transmembrane transport; iron ion transport; iron ion homeostasis; erythrocyte differentiation | |
| SFXN2 | transmembrane transport; iron ion homeostasis | |
| SGCB | cytoskeleton organization; muscle organ development | |
| SGCE | cell-matrix adhesion; muscle organ development | |
| SGCG | muscle organ development; cytoskeleton organization | |
| SGCZ | cytoskeleton organization; cellular membrane organization; muscle cell homeostasis; muscle cell development | |
| SGF29 | establishment of protein localization to chromatin; histone H3 acetylation; chromatin modification; regulation of transcription, DNA-dependent | |
| SGIP1 | positive regulation of feeding behavior; positive regulation of energy homeostasis; response to dietary excess; positive regulation of receptor-mediated endocytosis | |
| SGK1 | regulation of sequence-specific DNA binding transcription factor activity; regulation of catalytic activity; regulation of apoptotic process; regulation of cell proliferation; positive regulation of transporter activity; regulation of cell migration; regulation of blood pressure; long-term memory; response to stress; sodium ion transport; protein phosphorylation; regulation of cell growth; renal sodium ion absorption; regulation of gastric acid secretion | |
| SGK2 | response to oxidative stress; regulation of cell growth; protein phosphorylation; intracellular protein kinase cascade; positive regulation of transporter activity; regulation of cell proliferation | |
| SGK223 | - | |
| SGK494 | - | |
| SGMS2 | small molecule metabolic process; sphingolipid biosynthetic process; sphingomyelin biosynthetic process; sphingolipid metabolic process; lipid metabolic process | |
| SGOL1 | mitotic cell cycle; cell division; meiotic chromosome segregation; M phase of mitotic cell cycle; centriole-centriole cohesion; mitotic prometaphase; attachment of spindle microtubules to kinetochore; chromosome segregation | |
| SGOL2 | mitotic prometaphase; meiotic sister chromatid cohesion, centromeric; cell division; protein localization; meiosis; chromosome segregation; M phase of mitotic cell cycle; mitotic cell cycle | |
| SGPL1 | face morphogenesis; palate development; Leydig cell differentiation; regulation of multicellular organism growth; small molecule metabolic process; platelet-derived growth factor receptor signaling pathway; fibroblast migration; androgen metabolic process; spermatogenesis; apoptotic process; nitrogen compound metabolic process; female gonad development; post-embryonic development; ceramide metabolic process; sphingolipid metabolic process; lipid metabolic process; estrogen metabolic process; carboxylic acid metabolic process; kidney development; vasculogenesis; luteinization; skeletal system morphogenesis; hemopoiesis; sphingolipid biosynthetic process; sphingolipid catabolic process | |
| SGPP2 | sphingolipid metabolic process; small molecule metabolic process; sphingolipid biosynthetic process; sphingosine metabolic process | |
| SGSH | proteoglycan metabolic process | |
| SGSM2 | - | |
| SGSM3 | Rap protein signal transduction; cell cycle; positive regulation of protein catabolic process; cell cycle arrest; regulation of Rab protein signal transduction | |
| SGTA | interspecies interaction between organisms | |
| SH2B1 | intracellular signal transduction; blood coagulation | |
| SH2D3A | small GTPase mediated signal transduction; JNK cascade | |
| SH2D4A | negative regulation of phosphatase activity | |
| SH2D4B | - | |
| SH2D5 | - | |
| SH3BGR | protein complex assembly | |
| SH3BGRL | - | |
| SH3BP1 | signal transduction | |
| SH3BP4 | endocytosis | |
| SH3BP5 | signal transduction; intracellular signal transduction | |
| SH3BP5L | - | |
| SH3D19 | positive regulation of membrane protein ectodomain proteolysis; regulation of cell morphogenesis; cellular membrane organization; cytoskeleton organization; post-Golgi vesicle-mediated transport | |
| SH3D21 | - | |
| SH3GL1 | endocytosis; signal transduction; central nervous system development | |
| SH3GL2 | central nervous system development; regulation of receptor internalization; post-Golgi vesicle-mediated transport; signal transduction; epidermal growth factor receptor signaling pathway; axon guidance; cellular membrane organization; negative regulation of epidermal growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; synaptic vesicle endocytosis | |
| SH3GLB1 | positive regulation of protein oligomerization; apoptotic process; anti-apoptosis; signal transduction; protein oligomerization; filopodium assembly | |
| SH3KBP1 | apoptotic process; endocytosis; cytoskeleton organization; epidermal growth factor receptor signaling pathway; cell-cell signaling; regulation of cell shape; cell migration; negative regulation of epidermal growth factor receptor signaling pathway | |
| SH3PXD2A | cell communication; superoxide metabolic process | |
| SH3PXD2B | cell differentiation; extracellular matrix disassembly; positive regulation of fat cell differentiation; bone development; adipose tissue development; podosome assembly; protein localization in membrane; cell communication; heart development; superoxide metabolic process; skeletal system development; eye development | |
| SH3RF1 | induction of apoptosis; negative regulation of extrinsic apoptotic signaling pathway; regulation of JNK cascade; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process | |
| SH3RF2 | negative regulation of phosphatase activity | |
| SH3TC1 | - | |
| SHANK1 | protein complex assembly; protein localization to synapse; neuromuscular process controlling balance; dendritic spine morphogenesis; long-term memory; nervous system development; cell differentiation; associative learning; cytoskeletal anchoring at plasma membrane; positive regulation of excitatory postsynaptic membrane potential; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | |
| SHANK2 | intracellular signal transduction | |
| SHB | angiogenesis; cell differentiation; multicellular organismal development; signal transduction; apoptotic process; B cell proliferation | |
| SHBG | primary spermatocyte growth; hormone transport | |
| SHCBP1 | - | |
| SHCBP1L | - | |
| SHD | - | |
| SHE | - | |
| SHISA2 | multicellular organismal development | |
| SHKBP1 | potassium ion transport | |
| SHMT1 | protein homotetramerization; protein tetramerization; folic acid metabolic process; carnitine biosynthetic process; small molecule metabolic process; cellular nitrogen compound metabolic process; purine base biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process; one-carbon metabolic process; L-serine catabolic process; glycine biosynthetic process from serine | |
| SHPK | carbohydrate metabolic process | |
| SHPRH | nucleosome assembly; DNA repair | |
| SHQ1 | ribonucleoprotein complex assembly | |
| SHROOM1 | cell morphogenesis; actin filament bundle assembly | |
| SHROOM2 | camera-type eye development; cellular pigment accumulation; ear development; cell migration; eye pigment granule organization; cell-cell junction maintenance; camera-type eye morphogenesis; brain development; multicellular organismal development; lens morphogenesis in camera-type eye; cell morphogenesis; negative regulation of actin filament depolymerization; establishment of melanosome localization; apical protein localization; melanosome organization; actin filament bundle assembly | |
| SHROOM3 | neural tube closure; columnar/cuboidal epithelial cell development; cell morphogenesis; apical protein localization; cellular pigment accumulation; actin cytoskeleton organization; regulation of cell shape; pattern specification process | |
| SHROOM4 | cell morphogenesis; actin filament organization; multicellular organismal development; brain development; actin cytoskeleton organization; cognition | |
| SHTN1 | multicellular organismal development; axon guidance | |
| SI | small molecule metabolic process; polysaccharide digestion; response to starvation; response to vitamin A; response to glucocorticoid stimulus; carbohydrate metabolic process; response to insulin stimulus; response to fructose stimulus; response to sucrose stimulus; response to nutrient; aging | |
| SIDT1 | - | |
| SIDT2 | - | |
| SIGLEC1 | cell-matrix adhesion; endocytosis; inflammatory response; cell-cell adhesion | |
| SIGLEC11 | cell adhesion | |
| SIGLEC12 | cell adhesion | |
| SIGLEC14 | cell adhesion | |
| SIGLEC5 | cell adhesion | |
| SIGLEC7 | cell adhesion | |
| SIGLEC8 | cell adhesion; signal transduction | |
| SIGLEC9 | cell surface receptor signaling pathway; cell adhesion | |
| SIGLECL1 | - | |
| SIK1 | signal transduction by p53 class mediator resulting in induction of anoikis; cardiac muscle cell differentiation; intracellular protein kinase cascade; cell cycle; protein phosphorylation; regulation of sodium ion transport; multicellular organismal development; regulation of mitotic cell cycle; regulation of myotube differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of triglyceride biosynthetic process; negative regulation of CREB transcription factor activity; regulation of cell differentiation; negative regulation of gluconeogenesis; protein autophosphorylation | |
| SIK2 | regulation of insulin receptor signaling pathway; protein autophosphorylation; intracellular protein kinase cascade; protein phosphorylation | |
| SIK3 | protein phosphorylation | |
| SIM1 | regulation of transcription, DNA-dependent; ureteric bud development; multicellular organismal development; nervous system development; cell differentiation | |
| SIM2 | embryonic pattern specification; lung development; cell differentiation; nervous system development; multicellular organismal development; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| SIN3A | small molecule metabolic process; negative regulation of transcription, DNA-dependent; interphase of mitotic cell cycle; cellular lipid metabolic process; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; negative regulation of apoptotic process; cellular protein localization; response to organic nitrogen; blood coagulation; aging; DNA replication; in utero embryonic development | |
| SIN3B | cellular lipid metabolic process; cardiac muscle tissue development; skeletal muscle tissue development; small molecule metabolic process; negative regulation of transcription, DNA-dependent | |
| SIPA1 | positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; negative regulation of cell cycle; intracellular signal transduction; positive regulation of Rap GTPase activity; negative regulation of cell growth; cell proliferation; signal transduction; negative regulation of cell adhesion; cytoskeleton organization | |
| SIPA1L1 | regulation of small GTPase mediated signal transduction; regulation of axonogenesis; actin cytoskeleton reorganization; regulation of Rap GTPase activity; activation of Rap GTPase activity; ephrin receptor signaling pathway; regulation of synaptic plasticity; regulation of dendritic spine morphogenesis | |
| SIPA1L2 | regulation of small GTPase mediated signal transduction | |
| SIPA1L3 | regulation of small GTPase mediated signal transduction | |
| SIRPA | cell adhesion; blood coagulation; leukocyte migration | |
| SIRPB2 | - | |
| SIRPD | - | |
| SIRT1 | regulation of peroxisome proliferator activated receptor signaling pathway; regulation of bile acid biosynthetic process; single strand break repair; negative regulation of androgen receptor signaling pathway; regulation of cell proliferation; regulation of protein import into nucleus, translocation; cellular triglyceride homeostasis; peptidyl-lysine deacetylation; regulation of smooth muscle cell apoptosis; fatty acid homeostasis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of insulin receptor signaling pathway; white fat cell differentiation; negative regulation of helicase activity; negative regulation of NF-kappaB transcription factor activity; negative regulation of protein kinase B signaling cascade; response to insulin stimulus; negative regulation of peptidyl-lysine acetylation; negative regulation of sequence-specific DNA binding transcription factor activity; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; prote | |
| SIRT4 | chromatin silencing; protein ADP-ribosylation; protein deacetylation; negative regulation of insulin secretion | |
| SIRT7 | protein deacetylation; positive regulation of transcription on exit from mitosis; rRNA transcription | |
| SIT1 | signal transduction; regulation of T cell activation | |
| SIX1 | positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; thymus development; positive regulation of mesenchymal cell proliferation involved in ureter development; generation of neurons; embryonic cranial skeleton morphogenesis; embryonic skeletal system morphogenesis; inner ear development; myoblast migration; pharyngeal system development; otic vesicle development; metanephric mesenchyme development; regulation of branch elongation involved in ureteric bud branching; positive regulation of ureteric bud formation; mesonephric tubule formation; ureter smooth muscle cell differentiation; positive regulation of secondary heart field cardioblast proliferation; positive regulation of branching involved in ureteric bud morphogenesis; ureteric bud development; negative regulation of neuron apoptosis; regulation of neuron differentiation; branching involved in ureteric bud morphogenesis; organ induction; kidney development; outflow tract morphogenesis; | |
| SIX2 | kidney development; mesenchymal to epithelial transition involved in metanephros morphogenesis; regulation of transcription, DNA-dependent; chondrocyte differentiation; metanephros development; protein import into nucleus; multicellular organismal development; mesodermal cell fate specification; cell proliferation; anatomical structure morphogenesis; middle ear morphogenesis; negative regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; embryonic cranial skeleton morphogenesis | |
| SIX3 | camera-type eye development; negative regulation of Wnt receptor signaling pathway; forebrain anterior/posterior pattern specification; telencephalon development; diencephalon development; visual perception; brain development; multicellular organismal development; protein import into nucleus; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; lens induction in camera-type eye | |
| SIX4 | negative regulation of neuron apoptosis; regulation of branch elongation involved in ureteric bud branching; multicellular organismal development; skeletal muscle tissue development; metanephric mesenchyme development; anatomical structure morphogenesis; inner ear morphogenesis; positive regulation of transcription from RNA polymerase II promoter; thymus development; generation of neurons; embryonic cranial skeleton morphogenesis; myoblast migration; positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of ureteric bud formation | |
| SIX5 | spermatid development; multicellular organismal development; negative regulation of cell proliferation; lens development in camera-type eye | |
| SIX6 | visual perception; multicellular organismal development; organ morphogenesis | |
| SKAP2 | signal transduction; protein complex assembly; negative regulation of cell proliferation; B cell activation | |
| SKIL | regulation of apoptotic process; lymphocyte homeostasis; cell cycle arrest; skeletal muscle tissue development; negative regulation of transforming growth factor beta receptor signaling pathway; blastocyst formation; response to growth factor stimulus; negative regulation of transcription from RNA polymerase II promoter; lens fiber cell differentiation; negative regulation of cell differentiation; response to antibiotic; positive regulation of axonogenesis; protein heterotrimerization; protein homotrimerization | |
| SKIV2L2 | maturation of 5.8S rRNA; nuclear mRNA splicing, via spliceosome; RNA splicing | |
| SKOR1 | negative regulation of BMP signaling pathway; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transforming growth factor beta receptor signaling pathway | |
| SLAMF1 | lymphocyte activation; interspecies interaction between organisms; positive regulation of cell proliferation | |
| SLAMF6 | - | |
| SLAMF7 | cell adhesion; natural killer cell mediated cytotoxicity; natural killer cell activation | |
| SLAMF8 | - | |
| SLAMF9 | - | |
| SLC10A2 | small molecule metabolic process; bile acid and bile salt transport; organic anion transport; bile acid metabolic process; sodium ion transport; ion transport; transport | |
| SLC10A4 | sodium ion transport; ion transport | |
| SLC10A7 | sodium ion transport; ion transport | |
| SLC11A1 | wound healing; response to interferon-gamma; positive regulation of interferon-gamma production; interleukin-3 production; interleukin-2 production; response to lipopolysaccharide; activation of protein kinase activity; nitrite transport; positive regulation of gene expression; response to bacterium; macrophage activation; defense response to bacterium; defense response to protozoan; iron ion homeostasis; L-arginine import; vacuolar acidification; immune response; inflammatory response; phagocytosis; cellular iron ion homeostasis; cellular cadmium ion homeostasis; manganese ion transport; iron ion transport; ion transport; positive regulation of T-helper 1 type immune response; positive regulation of dendritic cell antigen processing and presentation; T cell cytokine production; T cell proliferation involved in immune response; positive regulation of cytokine production; negative regulation of cytokine production; respiratory burst; positive regulation of phagocytosis; protein import into nucleus, translocati | |
| SLC11A2 | manganese ion transmembrane transport; zinc ion transmembrane transport; transmembrane transport; cadmium ion transmembrane transport; ferrous iron import; erythrocyte development; dendrite morphogenesis; multicellular organismal iron ion homeostasis; response to cadmium ion; response to lead ion; cobalt ion transport; copper ion transport; manganese ion transport; cellular iron ion homeostasis; activation of cysteine-type endopeptidase activity involved in apoptotic process; learning or memory; response to iron ion; response to manganese ion; nickel cation transmembrane transport; nickel cation transport; vanadium ion transport; ferrous iron transport; lead ion transport; proton transport; cellular response to oxidative stress; copper ion transmembrane transport; response to hypoxia; detection of oxygen; heme biosynthetic process; ion transport | |
| SLC12A2 | ammonium transport; sodium ion transport; potassium ion transport; mammary duct terminal end bud growth; branching involved in mammary gland duct morphogenesis; transmembrane transport; ion transport; transepithelial chloride transport; multicellular organism growth; detection of mechanical stimulus involved in sensory perception of sound; transport; transepithelial ammonium transport | |
| SLC12A4 | potassium ion transport; sodium ion transport; chloride transport; cell volume homeostasis; transmembrane transport; ion transport; transport | |
| SLC12A5 | chloride transport; sodium ion transport; potassium ion transport; cellular ion homeostasis; ammonium transport; intracellular pH reduction; transmembrane transport; ion transport; transport | |
| SLC12A6 | sodium ion transport; cellular hypotonic salinity response; transmembrane transport; chloride transport; potassium ion transport; ion transport; angiogenesis | |
| SLC12A7 | transport; ion transport; potassium ion transport; sodium ion transport; chloride transport; cell volume homeostasis; transmembrane transport | |
| SLC12A8 | transmembrane transport; potassium ion transport; ion transport | |
| SLC12A9 | transmembrane transport | |
| SLC13A1 | sodium ion transport; sulfate transport; ion transmembrane transport; transmembrane transport | |
| SLC13A2 | transport; ion transport; sodium ion transport; transmembrane transport | |
| SLC13A3 | transmembrane transport; anion transport; sodium ion transport; sodium ion export | |
| SLC13A5 | transmembrane transport; sodium ion transport; ion transport | |
| SLC14A2 | response to water deprivation; urea transport; transmembrane transport; urea transmembrane transport | |
| SLC15A2 | transport; transmembrane transport; drug transport; protein transport; ion transport | |
| SLC15A3 | transmembrane transport; protein transport; oligopeptide transport; ion transport | |
| SLC15A4 | protein transport; oligopeptide transport; ion transport; transmembrane transport | |
| SLC16A10 | transmembrane transport; aromatic amino acid transport; amino acid transport; ion transport | |
| SLC16A13 | transmembrane transport | |
| SLC16A3 | blood coagulation; pyruvate metabolic process; organic anion transport; monocarboxylic acid transport; small molecule metabolic process; leukocyte migration; transmembrane transport | |
| SLC16A5 | transmembrane transport; monocarboxylic acid transport; organic anion transport | |
| SLC16A6 | transmembrane transport; monocarboxylic acid transport | |
| SLC16A7 | transmembrane transport; pyruvate transport | |
| SLC16A9 | urate metabolic process; transmembrane transport | |
| SLC17A1 | transmembrane transport; ion transport; sodium ion transport; phosphate ion transport; sodium-dependent phosphate transport; urate metabolic process | |
| SLC17A2 | phosphate-containing compound metabolic process; ion transport; sodium ion transport; transmembrane transport | |
| SLC17A3 | urate metabolic process; phosphate ion transport; regulation of anion transport; drug transport; glucose-6-phosphate transport; urate transport; sodium ion transport; drug transmembrane transport; organic anion transport; ion transport | |
| SLC17A4 | phosphate-containing compound metabolic process; transmembrane transport; sodium ion transport; ion transport | |
| SLC17A5 | sialic acid transport; transmembrane transport; anion transport; ion transport | |
| SLC17A6 | transmembrane transport; ion transport; neurotransmitter transport; sodium ion transport | |
| SLC17A7 | transmembrane transport; long-term memory; ion transport; regulation of excitatory postsynaptic membrane potential; phosphate ion transport; sodium ion transport; glutamate secretion; L-glutamate transport; synaptic transmission, glutamatergic; sequestering of neurotransmitter; L-glutamate import; synaptic transmission; neurotransmitter secretion; sodium-dependent phosphate transport | |
| SLC17A8 | neurotransmitter transport; sodium ion transport; sensory perception of sound; transmembrane transport; L-amino acid transport; amino acid transmembrane transport; ion transport | |
| SLC17A9 | exocytosis; transmembrane transport | |
| SLC18A1 | cellular response to lithium ion; transmembrane transport; negative regulation of serotonin uptake; positive regulation of dopamine secretion; monoamine transport; neurotransmitter transport | |
| SLC18A2 | response to amphetamine; response to corticosterone stimulus; cellular response to ammonium ion; transmembrane transport; negative regulation of neurotransmitter transport; insulin secretion; endocytic recycling; cellular response to drug; response to cocaine; glucose homeostasis; response to starvation; locomotory behavior; response to herbicide; post-embryonic development; response to zinc ion; synaptic vesicle amine transport; synaptic transmission; neurotransmitter secretion; aging; monoamine transport; death | |
| SLC18A3 | synaptic transmission; acetylcholine transport; neurotransmitter secretion; transmembrane transport | |
| SLC18B1 | transmembrane transport | |
| SLC19A1 | folic acid transport; methotrexate transport; transport; water-soluble vitamin metabolic process; vitamin metabolic process; folic acid metabolic process; small molecule metabolic process | |
| SLC1A1 | amino acid transmembrane transport; ion transport; dicarboxylic acid transport; synaptic transmission; L-amino acid transport; L-glutamate transport; protein homooligomerization; L-glutamate import; transmembrane transport; D-aspartate import; sodium ion export | |
| SLC1A3 | gamma-aminobutyric acid biosynthetic process; response to drug; response to light stimulus; sensory perception of sound; synaptic transmission; dicarboxylic acid transport; ion transport; glutamate biosynthetic process; amino acid transmembrane transport; neurotransmitter uptake; response to inorganic substance; auditory behavior; malate-aspartate shuttle; response to antibiotic; cell morphogenesis involved in neuron differentiation; positive regulation of synaptic transmission; neuromuscular process controlling balance; L-glutamate import; transmembrane transport; D-aspartate import; sodium ion export; cranial nerve development; L-glutamate transport; L-amino acid transport; response to wounding | |
| SLC1A4 | threonine transport; hydroxyproline transport; transmembrane transport; L-serine transport; proline transport; L-cystine transport; L-alanine transport; glutamine transport; cognition; proline transmembrane transport; synaptic transmission, glutamatergic; amino acid transport; dicarboxylic acid transport; chloride transport; ion transport | |
| SLC1A5 | ion transport; transmembrane transport; neutral amino acid transport; glutamine transport; amino acid transport; dicarboxylic acid transport | |
| SLC1A6 | transmembrane transport; regulation of membrane potential; L-glutamate transport; aspartate transport; amino acid transmembrane transport; L-amino acid transport; synaptic transmission; dicarboxylic acid transport; ion transport | |
| SLC1A7 | transmembrane transport; L-glutamate transport; dicarboxylic acid transport; ion transport | |
| SLC20A1 | transport; ion transport; sodium ion transport; phosphate ion transport; phosphate-containing compound metabolic process; transmembrane transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction | |
| SLC20A2 | transport; ion transport; sodium ion transport; phosphate ion transport; interspecies interaction between organisms; transmembrane transport | |
| SLC22A1 | epinephrine transport; organic cation transport; establishment or maintenance of transmembrane electrochemical gradient; drug transmembrane transport; transmembrane transport | |
| SLC22A10 | - | |
| SLC22A11 | ion transport; organic anion transport; urate metabolic process; transmembrane transport | |
| SLC22A12 | urate metabolic process; ion transport; urate transport; cellular homeostasis; transmembrane transport; response to drug | |
| SLC22A14 | organic cation transport | |
| SLC22A16 | cell differentiation; transmembrane transport; acid secretion; ion transport; multicellular organismal development; spermatogenesis; single fertilization; organic cation transport; sperm motility; carnitine transport | |
| SLC22A17 | siderophore transport; ion transport; iron ion homeostasis | |
| SLC22A23 | ion transport | |
| SLC22A25 | transmembrane transport | |
| SLC22A4 | organic cation transport; quaternary ammonium group transport; carnitine metabolic process; body fluid secretion; carnitine transport; transmembrane transport; sodium ion transport; triglyceride metabolic process | |
| SLC22A6 | alpha-ketoglutarate transport; response to methotrexate; sodium-independent organic anion transport; transmembrane transport; organic anion transport | |
| SLC22A9 | transmembrane transport | |
| SLC23A1 | nucleobase-containing compound metabolic process; dehydroascorbic acid transport; transepithelial L-ascorbic acid transport; sodium ion export; small molecule metabolic process; L-ascorbic acid metabolic process; L-ascorbic acid transport; nucleobase transport; response to toxin; brain development; sodium ion transport; ion transport; water-soluble vitamin metabolic process; vitamin metabolic process | |
| SLC23A2 | water-soluble vitamin metabolic process; sodium ion transport; response to oxidative stress; ion transport; nucleobase transport; molecular hydrogen transport; L-ascorbic acid metabolic process; vitamin metabolic process; nucleobase-containing compound metabolic process; small molecule metabolic process; transepithelial L-ascorbic acid transport; L-ascorbic acid transport | |
| SLC23A3 | transmembrane transport | |
| SLC24A2 | visual perception; learning; memory; ion transport; potassium ion transport; sodium ion transport; long term synaptic depression; response to stimulus; transmembrane transport; long-term synaptic potentiation; cellular calcium ion homeostasis | |
| SLC24A4 | sodium ion transport; ion transport; transmembrane transport; potassium ion transport; calcium ion transport | |
| SLC24A5 | ion transport; calcium ion transport; potassium ion transport; response to stimulus; transmembrane transport; sodium ion transport | |
| SLC25A1 | mitochondrial citrate transport; triglyceride biosynthetic process; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process; transmembrane transport; long-chain fatty-acyl-CoA biosynthetic process; cellular lipid metabolic process; small molecule metabolic process | |
| SLC25A13 | transmembrane transport; response to calcium ion; cellular respiration; small molecule metabolic process; malate-aspartate shuttle; L-glutamate transport; amino acid transmembrane transport; carbohydrate metabolic process; glucose metabolic process; gluconeogenesis; ATP biosynthetic process; aspartate transport; transport; L-amino acid transport | |
| SLC25A16 | transmembrane transport; small molecule metabolic process; pantothenate metabolic process; coenzyme biosynthetic process; transport; water-soluble vitamin metabolic process; vitamin metabolic process | |
| SLC25A19 | transmembrane transport; deoxynucleotide transport | |
| SLC25A2 | small molecule metabolic process; cellular nitrogen compound metabolic process; transport; mitochondrial ornithine transport; urea cycle | |
| SLC25A23 | transmembrane transport | |
| SLC25A24 | transmembrane transport | |
| SLC25A25 | transmembrane transport | |
| SLC25A27 | generation of precursor metabolites and energy; transport | |
| SLC25A28 | ion transport; iron ion homeostasis | |
| SLC25A29 | transmembrane transport | |
| SLC25A30 | mitochondrial transport; transport | |
| SLC25A32 | mitochondrial transport; transport; water-soluble vitamin metabolic process; folic acid metabolic process; small molecule metabolic process; folic acid transport; vitamin metabolic process | |
| SLC25A33 | transport | |
| SLC25A44 | transmembrane transport | |
| SLC25A45 | transmembrane transport | |
| SLC25A46 | transport | |
| SLC26A10 | regulation of Rho protein signal transduction; transmembrane transport | |
| SLC26A11 | ion transport; sulfate transport; transmembrane transport | |
| SLC26A3 | ion transport; regulation of transcription, DNA-dependent; excretion; sulfate transport; ion transmembrane transport; transmembrane transport; anion transport | |
| SLC26A4 | sulfate transport; chloride transport; ion transport; transmembrane transport; inorganic anion transport; sensory perception of sound; regulation of pH; regulation of protein localization; iodide transport | |
| SLC26A5 | sensory perception of sound; sulfate transport; regulation of membrane potential; regulation of cell shape; transmembrane transport | |
| SLC26A6 | sulfate transport; ion transport; bicarbonate transport; ion transmembrane transport; transmembrane transport | |
| SLC26A7 | transmembrane transport; oxalate transport; bicarbonate transport; sulfate transport; chloride transport; ion transport | |
| SLC26A8 | oxalate transport; sulfate transport; spermatogenesis; ion transport; chloride transport; meiosis; multicellular organismal development; cell differentiation; transmembrane transport | |
| SLC26A9 | transmembrane transport; sulfate transport; ion transmembrane transport; regulation of pH; ion transport; chloride transport | |
| SLC27A3 | lipid metabolic process; fatty acid metabolic process | |
| SLC27A4 | medium-chain fatty acid transport; lipid metabolic process; transport; response to nutrient; fatty acid transport; long-chain fatty acid transport; very long-chain fatty acid catabolic process; skin development; transmembrane transport | |
| SLC27A5 | bile acid and bile salt transport; triglyceride mobilization; ketone body biosynthetic process; lipid metabolic process; fatty acid metabolic process; very long-chain fatty acid metabolic process; bile acid biosynthetic process; bile acid metabolic process; small molecule metabolic process; plasma membrane long-chain fatty acid transport | |
| SLC28A1 | transmembrane transport; nucleoside transport; nucleobase-containing compound metabolic process | |
| SLC29A2 | lactation; nucleobase-containing compound metabolic process; cell proliferation; uridine transport; adenine transport; guanine transport; nucleoside transport; cellular response to insulin stimulus; hypoxanthine transport; thymine transport; transmembrane transport | |
| SLC29A3 | transmembrane transport | |
| SLC2A1 | regulation of insulin secretion; water-soluble vitamin metabolic process; vitamin metabolic process; energy reserve metabolic process; carbohydrate metabolic process; response to osmotic stress; carbohydrate transport; hexose transport; glucose transport; L-ascorbic acid metabolic process; hexose transmembrane transport; transmembrane transport; cellular response to glucose starvation; small molecule metabolic process | |
| SLC2A10 | transmembrane transport; glucose transport; carbohydrate transport | |
| SLC2A11 | carbohydrate transport; transmembrane transport | |
| SLC2A12 | carbohydrate transport; transmembrane transport | |
| SLC2A13 | transmembrane transport | |
| SLC2A14 | multicellular organismal development; spermatogenesis; carbohydrate transport; cell differentiation | |
| SLC2A2 | regulation of insulin secretion; energy reserve metabolic process; transmembrane transport; small molecule metabolic process; response to peptide hormone stimulus; hexose transmembrane transport; endocrine pancreas development; glucose transport; fructose transport; response to glucose stimulus; hexose transport; carbohydrate transport; carbohydrate metabolic process | |
| SLC2A4 | response to ethanol; glucose transport; cellular response to insulin stimulus; glucose homeostasis; transmembrane transport; brown fat cell differentiation; glucose import; carbohydrate transport; small molecule metabolic process; hexose transport; carbohydrate metabolic process | |
| SLC2A4RG | regulation of transcription, DNA-dependent | |
| SLC2A5 | hexose transport; fructose transport; glucose transport; carbohydrate metabolic process; carbohydrate transport; small molecule metabolic process; transmembrane transport | |
| SLC2A6 | carbohydrate transport; glucose transport; transmembrane transport | |
| SLC2A8 | insulin receptor signaling pathway; carbohydrate transport; response to hypoxia; glucose transport; hexose transmembrane transport; male meiosis I; transmembrane transport; carbohydrate metabolic process | |
| SLC2A9 | hexose transmembrane transport; carbohydrate transport; urate metabolic process; transmembrane transport; glucose transport | |
| SLC30A10 | transmembrane transport; zinc ion transport | |
| SLC30A6 | transmembrane transport; zinc ion transport | |
| SLC30A7 | transmembrane transport; sequestering of zinc ion; zinc ion transport | |
| SLC30A8 | zinc ion transport; cellular zinc ion homeostasis; response to glucose stimulus; regulation of sequestering of zinc ion; zinc ion transmembrane transport; response to interleukin-1; regulation of vesicle-mediated transport; insulin secretion; positive regulation of insulin secretion; sequestering of zinc ion; transmembrane transport; glucose homeostasis; response to interferon-gamma | |
| SLC30A9 | transmembrane transport; zinc ion transport; regulation of transcription, DNA-dependent; nucleotide-excision repair | |
| SLC31A1 | transmembrane transport; ion transport; copper ion transport; copper ion transmembrane transport | |
| SLC34A1 | bone remodeling; ion transport; sodium ion transport; transmembrane transport; phosphate ion homeostasis; response to mercury ion; response to cadmium ion; sodium-dependent phosphate transport; response to magnesium ion; response to lead ion; phosphate ion transport | |
| SLC34A2 | response to estradiol stimulus; phosphate ion transmembrane transport; response to estrogen stimulus; sodium-dependent phosphate transport; transmembrane transport; aging; phosphate ion transport; sodium ion transport; ion transport; cellular phosphate ion homeostasis; in utero embryonic development; response to fructose stimulus | |
| SLC35A3 | UDP-N-acetylglucosamine transport; transport; transmembrane transport; UDP-N-acetylglucosamine metabolic process | |
| SLC35A5 | transport | |
| SLC35B2 | positive regulation of I-kappaB kinase/NF-kappaB cascade; 3'-phosphoadenosine 5'-phosphosulfate transport; transmembrane transport; signal transduction | |
| SLC35B3 | transmembrane transport | |
| SLC35B4 | transmembrane transport; UDP-xylose transport; UDP-N-acetylglucosamine transport; carbohydrate transport | |
| SLC35C1 | carbohydrate transport; lipid glycosylation; transmembrane transport | |
| SLC35C2 | transport | |
| SLC35E1 | transport | |
| SLC35E3 | - | |
| SLC35F1 | transport | |
| SLC35F3 | transport | |
| SLC35F5 | transport | |
| SLC35F6 | - | |
| SLC35G2 | - | |
| SLC36A1 | ion transport; amino acid transport; transmembrane transport | |
| SLC36A2 | ion transport; proton transport; glycine transport; ion transmembrane transport; proline transmembrane transport; transmembrane transport; amino acid transport | |
| SLC36A4 | L-alanine transport; proline transport; amino acid transport; transport; tryptophan transport | |
| SLC37A2 | transmembrane transport; carbohydrate transport | |
| SLC37A3 | transmembrane transport; carbohydrate transport | |
| SLC38A1 | sodium ion transport; neurotransmitter uptake; ion transport; amino acid transport; synaptic transmission; neutral amino acid transport; transmembrane transport | |
| SLC38A10 | amino acid transport; sodium ion transport; ion transport | |
| SLC38A4 | transmembrane transport; amino acid transport; sodium ion transport; ion transport | |
| SLC38A5 | transmembrane transport; amino acid transport; ion transport | |
| SLC38A6 | sodium ion transport; ion transport; amino acid transport | |
| SLC38A8 | ion transport; sodium ion transport; amino acid transport | |
| SLC38A9 | ion transport; sodium ion transport; amino acid transport | |
| SLC39A10 | zinc ion transport; transmembrane transport; ion transport | |
| SLC39A11 | ion transport; zinc ion transport; transmembrane transport | |
| SLC39A12 | transmembrane transport; zinc ion transport; ion transport | |
| SLC39A13 | ion transport; cellular zinc ion homeostasis; transmembrane transport; zinc ion transmembrane transport | |
| SLC39A14 | zinc ion import; zinc ion transmembrane transport; transmembrane transport; ion transport; cellular zinc ion homeostasis | |
| SLC39A2 | zinc ion transmembrane transport; transmembrane transport; zinc ion transport; ion transport | |
| SLC39A4 | ion transport; cellular zinc ion homeostasis; cellular response to zinc ion starvation; transmembrane transport | |
| SLC39A6 | zinc ion transmembrane transport; ion transport; zinc ion import; transmembrane transport; cellular zinc ion homeostasis | |
| SLC39A9 | ion transport; zinc ion transport; transmembrane transport | |
| SLC3A1 | transmembrane transport; L-cystine transport; basic amino acid transport; amino acid transport; ion transport; amino acid transmembrane transport; carbohydrate metabolic process; cellular amino acid metabolic process | |
| SLC3A2 | leucine import; carbohydrate metabolic process; ion transport; calcium ion transport; amino acid transport; blood coagulation; tryptophan transport; cell growth; leukocyte migration; transmembrane transport | |
| SLC40A1 | multicellular organismal iron ion homeostasis; iron ion transmembrane transport; lymphocyte homeostasis; endothelium development; ion transport; transmembrane transport; spleen trabecula formation; cellular iron ion homeostasis; apoptotic process; anatomical structure morphogenesis | |
| SLC41A2 | transmembrane transport | |
| SLC41A3 | - | |
| SLC43A1 | neutral amino acid transport; amino acid transport; ion transport; amino acid transmembrane transport; transmembrane transport | |
| SLC43A3 | transmembrane transport | |
| SLC44A1 | choline transport; transmembrane transport | |
| SLC44A2 | transmembrane transport; signal transduction; choline transport; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| SLC44A3 | transmembrane transport | |
| SLC44A5 | transmembrane transport | |
| SLC45A1 | carbohydrate transport; transmembrane transport | |
| SLC45A2 | visual perception; melanin biosynthetic process; response to stimulus; developmental pigmentation | |
| SLC45A4 | transport | |
| SLC46A2 | transport; transmembrane transport | |
| SLC47A2 | transmembrane transport | |
| SLC4A1 | ion transport; anion transport; chloride transport; cellular ion homeostasis; bicarbonate transport; ion transmembrane transport; transmembrane transport | |
| SLC4A11 | fluid transport; borate transport; sodium ion transmembrane transport; phosphoenolpyruvate-dependent sugar phosphotransferase system; sodium ion transport; bicarbonate transport; borate transmembrane transport; proton transport; cellular cation homeostasis | |
| SLC4A1AP | - | |
| SLC4A3 | transmembrane transport; regulation of intracellular pH; ion transmembrane transport; bicarbonate transport; ion transport; transport | |
| SLC4A4 | transmembrane transport; bicarbonate transport; sodium ion transport; ion transport; transport | |
| SLC4A5 | ion transport; sodium ion transport; bicarbonate transport; transmembrane transport | |
| SLC4A7 | ion transport; sodium ion transport; bicarbonate transport; transmembrane transport | |
| SLC4A8 | transmembrane transport; ion transport; sodium ion transport; bicarbonate transport | |
| SLC50A1 | transport; carbohydrate transport; glucoside transport; positive regulation of gene expression, epigenetic | |
| SLC51A | - | |
| SLC52A2 | riboflavin transport; transport | |
| SLC5A1 | hexose transport; glucose transport; hexose transmembrane transport; small molecule metabolic process; intestinal absorption; transmembrane transport; carbohydrate transport; sodium ion transport; ion transport; carbohydrate metabolic process; metanephros development | |
| SLC5A11 | sodium ion transport; ion transport; apoptotic process; carbohydrate transport; transmembrane transport | |
| SLC5A2 | carbohydrate transport; glucose transport; transmembrane transport; sodium ion transport; carbohydrate metabolic process; transport; ion transport | |
| SLC5A3 | inositol metabolic process; transport; ion transport; sodium ion transport; peripheral nervous system development; myo-inositol transport; regulation of respiratory gaseous exchange; transmembrane transport | |
| SLC5A4 | sodium ion transport; ion transport; carbohydrate transport; transmembrane transport | |
| SLC5A5 | thyroid hormone generation; transport; ion transport; sodium ion transport; iodide transport; cellular nitrogen compound metabolic process; small molecule metabolic process; transmembrane transport; cellular response to cAMP; cellular response to gonadotropin stimulus | |
| SLC5A6 | small molecule metabolic process; transmembrane transport; pantothenate metabolic process; pantothenate transmembrane transport; biotin transport; sodium ion transport; ion transport; transport; biotin metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process | |
| SLC5A7 | transmembrane transport; choline transport; acetylcholine biosynthetic process; neuromuscular synaptic transmission; synaptic transmission, cholinergic; synaptic transmission; neurotransmitter secretion; sodium ion transport; ion transport | |
| SLC5A8 | sodium ion transport; ion transport; apoptotic process; transmembrane transport | |
| SLC5A9 | ion transport; sodium ion transport; transmembrane transport | |
| SLC6A1 | response to calcium ion; response to cocaine; transmembrane transport; gamma-aminobutyric acid import; transport; protein homooligomerization; response to estradiol stimulus; negative regulation of synaptic transmission, GABAergic; response to purine-containing compound; positive regulation of gamma-aminobutyric acid secretion; response to lead ion; response to organic nitrogen; response to sucrose stimulus; response to toxin; learning; neurotransmitter secretion; synaptic transmission | |
| SLC6A11 | neurotransmitter transport; synaptic transmission; neurotransmitter secretion; brain development; response to drug; transmembrane transport | |
| SLC6A12 | response to organic substance; cellular hyperosmotic response; transmembrane transport; transport; ion transport; amino acid transport; synaptic transmission; neurotransmitter secretion; cellular water homeostasis | |
| SLC6A13 | transmembrane transport; neurotransmitter transport; synaptic transmission; neurotransmitter secretion | |
| SLC6A14 | ion transport; transmembrane transport; amino acid transmembrane transport; response to toxin; amino acid transport; transport; cellular amino acid metabolic process; neurotransmitter transport | |
| SLC6A15 | L-amino acid transport; sodium ion transport; sodium ion export; transmembrane transport; proline transmembrane transport; proline transport; leucine transport; neutral amino acid transport; amino acid transport; neurotransmitter transport; ion transport | |
| SLC6A16 | neurotransmitter transport | |
| SLC6A17 | alanine transport; proline transport; leucine transport; glycine transport; neutral amino acid transport; neurotransmitter transport | |
| SLC6A18 | transmembrane transport; response to osmotic stress; amino acid transport; ion transport; neurotransmitter transport | |
| SLC6A19 | amino acid transmembrane transport; ion transport; neurotransmitter transport; amino acid transport; response to nutrient; transmembrane transport | |
| SLC6A2 | transport; monoamine transport; response to pain; transmembrane transport; synaptic transmission; neurotransmitter transport | |
| SLC6A20 | ion transport; neurotransmitter transport; amino acid transmembrane transport; amino acid transport; glycine transport; proline transport; transmembrane transport | |
| SLC6A3 | lactation; aging; transmembrane transport; sensory perception of smell; locomotory behavior; synaptic transmission; neurotransmitter transport; transport; cell death; response to iron ion; monoamine transport; prepulse inhibition; positive regulation of multicellular organism growth; response to cAMP; response to ethanol; response to drug; dopamine catabolic process; adenohypophysis development; response to nicotine; dopamine transport; dopamine biosynthetic process; response to cocaine; neurotransmitter biosynthetic process; regulation of dopamine metabolic process | |
| SLC6A4 | negative regulation of cerebellar granule cell precursor proliferation; neurotransmitter transport; serotonin transport; brain development; response to nutrient; memory; circadian rhythm; response to toxin; response to organic substance; positive regulation of gene expression; monoamine transport; thalamus development; negative regulation of synaptic transmission, dopaminergic; response to estradiol stimulus; vasoconstriction; response to drug; sperm ejaculation; negative regulation of neuron differentiation; positive regulation of cell cycle; cellular response to cGMP; cellular response to retinoic acid; serotonin uptake; protein homooligomerization; protein oligomerization; response to hypoxia | |
| SLC6A6 | amino acid transmembrane transport; cellular amino acid metabolic process; transport; ion transport; neurotransmitter transport; amino acid transport; transmembrane transport | |
| SLC6A7 | amino acid transport; transmembrane transport; proline transport; neurotransmitter transport; transport | |
| SLC6A9 | amino acid transmembrane transport; transport; neurotransmitter transport; transmembrane transport | |
| SLC7A10 | ion transport; blood coagulation; amino acid transport; D-alanine transport; D-serine transport; L-serine transport; neutral amino acid transport; transmembrane transport; leukocyte migration | |
| SLC7A13 | transport | |
| SLC7A14 | transport; negative regulation of phosphatase activity | |
| SLC7A3 | transmembrane transport; ion transmembrane transport; regulation of TOR signaling cascade; L-amino acid transport; amino acid transport; cation transport; ion transport | |
| SLC7A4 | transport; basic amino acid transport; cellular amino acid metabolic process | |
| SLC7A5 | ion transport; transport; amino acid transmembrane transport; cellular amino acid metabolic process; transmembrane transport; leukocyte migration; cell differentiation; neutral amino acid transport; blood coagulation; nervous system development; multicellular organismal development; amino acid transport | |
| SLC7A6 | protein complex assembly; transmembrane transport; leukocyte migration; blood coagulation; amino acid transport; ion transport; transport; cellular amino acid metabolic process; amino acid transmembrane transport | |
| SLC7A7 | transmembrane transport; leukocyte migration; blood coagulation; amino acid transport; ion transport; cellular amino acid metabolic process; protein complex assembly; transport | |
| SLC7A9 | transmembrane transport; cellular amino acid metabolic process; L-cystine transport; neutral amino acid transport; blood coagulation; protein complex assembly; amino acid transmembrane transport; amino acid transport; ion transport; transport; leukocyte migration | |
| SLC8A1 | regulation of sodium ion transport; response to hypoxia; sodium ion export; cellular response to cAMP; calcium ion transmembrane transport; calcium ion transport into cytosol; telencephalon development; ion transport; sodium ion transport; calcium ion transport; cellular calcium ion homeostasis; muscle contraction; cell communication; response to nutrient; blood coagulation; cytosolic calcium ion transport; transmembrane transport; regulation of calcium ion transport; response to hydrogen peroxide; response to drug; response to ATP; response to glucose stimulus | |
| SLC8A2 | calcium ion transport into cytosol; transmembrane transport; response to vitamin D; telencephalon development; blood coagulation; cell communication; calcium ion transport; sodium ion transport; ion transport | |
| SLC8A3 | blood coagulation; cell communication; sodium ion transport; ion transport; calcium ion transport; cellular response to cAMP; calcium ion transport into cytosol; transmembrane transport; telencephalon development | |
| SLC9A1 | response to organic cyclic compound; sodium ion transport; regulation of pH; intracellular protein kinase cascade; response to acidity; cation transport; ion transport; response to acid; proton transport; sodium ion export; transmembrane transport; positive regulation of anti-apoptosis; response to drug; cell differentiation; cell growth | |
| SLC9A2 | proton transport; transmembrane transport; sodium ion export; protein localization; regulation of pH; sodium ion transport; cation transport; ion transport | |
| SLC9A3 | cation transport; transmembrane transport; response to glucocorticoid stimulus; circadian rhythm; receptor-mediated endocytosis; regulation of pH; ion transport; regulation of sodium ion transport | |
| SLC9A5 | transport; ion transport; cation transport; sodium ion transport; regulation of pH; proton transport; transmembrane transport | |
| SLC9A7 | ion transport; cation transport; potassium ion transport; sodium ion transport; regulation of pH; transmembrane transport | |
| SLC9A9 | regulation of pH; transmembrane transport; sodium ion transport; cation transport; ion transport | |
| SLC9B2 | transmembrane transport; cation transport; sodium ion transport; proton transport | |
| SLC9C1 | cation transport; sodium ion transport; multicellular organismal development; spermatogenesis; cell differentiation; sperm motility; transmembrane transport | |
| SLC9C2 | transmembrane transport; sodium ion transport; cation transport | |
| SLCO1A2 | bile acid and bile salt transport; ion transport; bile acid metabolic process; transmembrane transport; small molecule metabolic process; sodium-independent organic anion transport; organic anion transport | |
| SLCO1B1 | transmembrane transport; ion transport; small molecule metabolic process; sodium-independent organic anion transport; bile acid metabolic process; bile acid and bile salt transport; organic anion transport | |
| SLCO1B3 | transmembrane transport; small molecule metabolic process; sodium-independent organic anion transport; bile acid and bile salt transport; organic anion transport; bile acid metabolic process; ion transport | |
| SLCO1C1 | ion transport; transmembrane transport; sodium-independent organic anion transport | |
| SLCO2A1 | sodium-independent organic anion transport; lipid transport; transmembrane transport | |
| SLCO3A1 | ion transport; sodium-independent organic anion transport; transmembrane transport | |
| SLCO4A1 | transmembrane transport; sodium-independent organic anion transport; thyroid hormone metabolic process; ion transport | |
| SLCO4C1 | spermatogenesis; transmembrane transport; sodium-independent organic anion transport; multicellular organismal development; ion transport; cell differentiation | |
| SLCO5A1 | - | |
| SLCO6A1 | - | |
| SLF2 | - | |
| SLFN13 | - | |
| SLFN5 | cell differentiation | |
| SLIT1 | cell differentiation; retinal ganglion cell axon guidance; multicellular organismal development; dorsal/ventral axon guidance; establishment of nucleus localization; negative regulation of axon extension involved in axon guidance; axon extension involved in axon guidance; forebrain morphogenesis; negative chemotaxis; negative regulation of synapse assembly; chemorepulsion involved in embryonic olfactory bulb interneuron migration; spinal cord development; motor axon guidance; brain development; axon guidance; nervous system development; tangential migration from the subventricular zone to the olfactory bulb | |
| SLIT2 | negative regulation of retinal ganglion cell axon guidance; negative regulation of neutrophil chemotaxis; negative regulation of mononuclear cell migration; ureteric bud development; negative regulation of protein phosphorylation; negative regulation of cellular response to growth factor stimulus; positive regulation of axonogenesis; cell migration involved in sprouting angiogenesis; negative regulation of leukocyte chemotaxis; multicellular organismal development; nervous system development; axon guidance; cellular response to hormone stimulus; negative regulation of cell migration; negative regulation of actin filament polymerization; cellular response to heparin; motor axon guidance; negative regulation of chemokine-mediated signaling pathway; apoptotic process involved in luteolysis; response to cortisol stimulus; negative regulation of small GTPase mediated signal transduction; retinal ganglion cell axon guidance; Roundabout signaling pathway; positive regulation of apoptotic process; negative regulation | |
| SLIT3 | negative regulation of cell growth; negative regulation of chemokine-mediated signaling pathway; apoptotic process involved in luteolysis; response to cortisol stimulus; negative chemotaxis; axon extension involved in axon guidance; Roundabout signaling pathway; cellular response to hormone stimulus; cell differentiation; chemorepulsion involved in embryonic olfactory bulb interneuron migration; axon guidance; nervous system development; multicellular organismal development | |
| SLITRK1 | axonogenesis | |
| SLITRK2 | axonogenesis | |
| SLITRK3 | axonogenesis | |
| SLITRK4 | - | |
| SLITRK5 | axonogenesis | |
| SLITRK6 | axonogenesis | |
| SLK | protein autophosphorylation; nucleotide-excision repair; apoptotic process | |
| SLMAP | muscle contraction; protein folding | |
| SLTM | apoptotic process; regulation of transcription, DNA-dependent | |
| SLU7 | nuclear mRNA splicing, via spliceosome; nuclear mRNA 3'-splice site recognition; alternative nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; intracellular protein transport; cellular response to stress | |
| SLX4 | nucleotide-excision repair; positive regulation of catalytic activity; DNA double-strand break processing involved in repair via single-strand annealing; DNA recombination; DNA repair; double-strand break repair via homologous recombination | |
| SLX4IP | - | |
| SMAD2 | embryonic foregut morphogenesis; response to cholesterol; pericardium development; palate development; regulation of binding; embryonic cranial skeleton morphogenesis; developmental growth; paraxial mesoderm morphogenesis; gastrulation; regulation of transforming growth factor beta receptor signaling pathway; positive regulation of epithelial to mesenchymal transition; anterior/posterior pattern specification; embryonic pattern specification; post-embryonic development; response to glucose stimulus; negative regulation of cell proliferation; endoderm development; positive regulation of transcription, DNA-dependent; zygotic specification of dorsal/ventral axis; SMAD protein complex assembly; common-partner SMAD protein phosphorylation; transforming growth factor beta receptor signaling pathway; mesoderm formation; in utero embryonic development; ureteric bud development; organ growth; primary miRNA processing; pancreas development; lung development; insulin secretion; intracellular signal transduction; cell fa | |
| SMAD3 | negative regulation of mitotic cell cycle; paraxial mesoderm morphogenesis; negative regulation of osteoblast proliferation; positive regulation of transcription, DNA-dependent; negative regulation of osteoblast differentiation; cell-cell junction organization; negative regulation of apoptotic process; positive regulation of transcription factor import into nucleus; negative regulation of protein catabolic process; T cell activation; wound healing; positive regulation of catenin import into nucleus; positive regulation of stress fiber assembly; positive regulation of canonical Wnt receptor signaling pathway; lens fiber cell differentiation; negative regulation of wound healing; transdifferentiation; pericardium development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of focal adhesion assembly; developmental growth; embryonic foregut morphogenesis; embryonic cranial skeleton morphogenesis; regulation of epithelial cell proliferation; negative regulation of inflamm | |
| SMAD4 | neuron fate commitment; developmental growth; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of protein catabolic process; regulation of transforming growth factor beta2 production; somite rostral/caudal axis specification; positive regulation of transforming growth factor beta receptor signaling pathway; BMP signaling pathway; negative regulation of cell growth; tissue morphogenesis; sebaceous gland development; formation of anatomical boundary; regulation of binding; regulation of hair follicle development; palate development; positive regulation of SMAD protein import into nucleus; SMAD protein signal transduction; negative regulation of cell death; nephrogenic mesenchyme morphogenesis; metanephric mesenchyme morphogenesis; response to transforming growth factor beta stimulus; regulation of transforming growth factor beta receptor signaling pathway; branching | |
| SMAD6 | immune response; response to laminar fluid shear stress; cell-substrate adhesion; negative regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; BMP signaling pathway; negative regulation of SMAD protein complex assembly; zygotic specification of dorsal/ventral axis; transforming growth factor beta receptor signaling pathway; ureteric bud development; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to estrogen stimulus; positive regulation of S phase of mitotic cell cycle; negative regulation of pathway-restricted SMAD protein phosphorylation | |
| SMAD9 | hindbrain development; midbrain development; BMP signaling pathway; positive regulation of cell differentiation; transforming growth factor beta receptor signaling pathway; protein phosphorylation; Mullerian duct regression; response to hypoxia; ureteric bud development; positive regulation of transcription, DNA-dependent; cellular response to organic cyclic compound | |
| SMAP1 | positive regulation of erythrocyte differentiation; regulation of ARF GTPase activity | |
| SMAP2 | regulation of ARF GTPase activity | |
| SMARCA2 | positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; aortic smooth muscle cell differentiation; negative regulation of cell growth; negative regulation of cell proliferation; nervous system development; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; chromatin remodeling; negative regulation of transcription from RNA polymerase II promoter | |
| SMARCA4 | negative regulation of S phase of mitotic cell cycle; nucleosome disassembly; neural retina development; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; negative regulation of androgen receptor signaling pathway; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; chromatin remodeling; positive regulation by host of viral transcription; negative regulation of cell growth; nervous system development; regulation of transcription, DNA-dependent | |
| SMARCA5 | chromatin silencing at rDNA; ATP catabolic process; double-strand break repair; chromatin assembly or disassembly; nucleosome assembly; chromatin remodeling; transcription initiation, DNA-dependent; regulation of transcription from RNA polymerase II promoter; embryo development; nucleosome positioning; CenH3-containing nucleosome assembly at centromere; ATP-dependent chromatin remodeling; positive regulation of transcription, DNA-dependent | |
| SMARCAD1 | regulation of DNA recombination; nucleotide metabolic process; chromatin modification; positive regulation of transcription, DNA-dependent; protein homooligomerization | |
| SMARCC1 | regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; organ morphogenesis; insulin receptor signaling pathway; nervous system development; chromatin remodeling; nucleosome disassembly | |
| SMARCC2 | regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; nervous system development; nucleosome disassembly; chromatin remodeling | |
| SMARCD1 | chromatin-mediated maintenance of transcription; nucleosome disassembly; chromatin remodeling; regulation of transcription from RNA polymerase II promoter; nervous system development | |
| SMARCE1 | negative regulation of transcription, DNA-dependent; nervous system development; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; nucleosome disassembly | |
| SMC1A | mitotic sister chromatid segregation; cell cycle checkpoint; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; nuclear mRNA splicing, via spliceosome; DNA repair; DNA recombination; cell division; sister chromatid cohesion; mitotic spindle organization; signal transduction in response to DNA damage; negative regulation of DNA endoreduplication; chromosome condensation; gene expression; response to radiation; RNA splicing; meiosis; mitotic metaphase/anaphase transition; mitotic sister chromatid cohesion | |
| SMC1B | DNA recombination; DNA repair; chromosome condensation; meiosis; sister chromatid cohesion; cell cycle | |
| SMC2 | DNA repair; DNA recombination; cell division; mitotic chromosome condensation; mitosis; sister chromatid cohesion; cell cycle | |
| SMC3 | DNA repair; mitotic spindle organization; sister chromatid cohesion; cell division; negative regulation of DNA endoreduplication; signal transduction; meiosis; mitotic metaphase/anaphase transition; DNA mediated transformation; mitosis; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; regulation of DNA replication | |
| SMC4 | mitotic sister chromatid segregation; DNA repair; DNA recombination; cell cycle; sister chromatid cohesion; mitotic chromosome condensation; cell division | |
| SMC5 | telomere maintenance via recombination; double-strand break repair via homologous recombination; DNA repair; double-strand break repair via nonhomologous end joining; DNA recombination; positive regulation of maintenance of mitotic sister chromatid cohesion; cellular senescence; positive regulation of mitotic metaphase/anaphase transition | |
| SMC6 | cellular senescence; DNA recombination; DNA repair; telomere maintenance via recombination | |
| SMCO3 | - | |
| SMCP | sperm motility; penetration of zona pellucida; binding of sperm to zona pellucida | |
| SMCR8 | - | |
| SMDT1 | - | |
| SMG6 | RNA metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; telomere maintenance; mRNA export from nucleus; gene expression; regulation of dephosphorylation; mRNA metabolic process | |
| SMG7 | mRNA export from nucleus; RNA metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA metabolic process; regulation of dephosphorylation | |
| SMG8 | RNA metabolic process; regulation of protein kinase activity; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; gene expression | |
| SMIM21 | - | |
| SMIM7 | - | |
| SMIM8 | - | |
| SMO | positive regulation of protein import into nucleus; neuron fate commitment; developmental growth; embryonic digestive tract morphogenesis; embryonic neurocranium morphogenesis; cell development; positive regulation of transcription from RNA polymerase II promoter; embryonic viscerocranium morphogenesis; positive regulation of smoothened signaling pathway; negative regulation of DNA binding; negative regulation of apoptotic process; muscle cell fate commitment; odontogenesis of dentin-containing tooth; multicellular organism growth; protein localization to nucleus; osteoblast proliferation; neuron projection regeneration; otolith morphogenesis; positive regulation of branching involved in ureteric bud morphogenesis; mammary gland epithelial cell differentiation; epithelial-mesenchymal cell signaling; detection of cell density by contact stimulus involved in contact inhibition; ciliary receptor clustering involved in smoothened signaling pathway; somite development; cellular response to cholesterol; renal syste | |
| SMOC1 | cell differentiation; multicellular organismal development; signal transduction; eye development; limb development; regulation of osteoblast differentiation | |
| SMOC2 | signal transduction | |
| SMOX | polyamine biosynthetic process; small molecule metabolic process; cellular nitrogen compound metabolic process; polyamine metabolic process; xenobiotic metabolic process; spermine catabolic process | |
| SMPD3 | sphingomyelin catabolic process; peptide hormone secretion; sphingolipid metabolic process; multicellular organismal development; cell cycle; glycosphingolipid metabolic process; small molecule metabolic process | |
| SMPDL3A | sphingomyelin catabolic process; metabolic process | |
| SMR3A | - | |
| SMR3B | - | |
| SMS | methionine metabolic process; polyamine metabolic process; spermine biosynthetic process; cellular nitrogen compound metabolic process; small molecule metabolic process | |
| SMTN | muscle organ development; smooth muscle contraction | |
| SMUG1 | DNA repair; base-excision repair; base-excision repair, AP site formation; metabolic process; depyrimidination | |
| SMURF1 | protein polyubiquitination; positive regulation of protein ubiquitination; ubiquitin-dependent SMAD protein catabolic process; negative regulation of BMP signaling pathway; protein export from nucleus; ectoderm development; protein ubiquitination; cell differentiation; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; receptor catabolic process; protein localization at cell surface; transforming growth factor beta receptor signaling pathway; protein modification process; negative regulation of ossification; negative regulation of transforming growth factor beta receptor signaling pathway; BMP signaling pathway | |
| SMURF2 | ubiquitin-dependent protein catabolic process; regulation of transforming growth factor beta receptor signaling pathway; protein ubiquitination; transforming growth factor beta receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process; BMP signaling pathway; ubiquitin-dependent SMAD protein catabolic process; negative regulation of transcription, DNA-dependent | |
| SMYD4 | - | |
| SMYD5 | - | |
| SNAI2 | white fat cell differentiation; negative regulation of apoptotic process; palate development; positive regulation of survival gene product expression; negative regulation of transcription from RNA polymerase II promoter; osteoblast differentiation; epithelial to mesenchymal transition; epithelial to mesenchymal transition involved in endocardial cushion formation; regulation of transcription, DNA-dependent; negative regulation of cell adhesion involved in substrate-bound cell migration; multicellular organismal development; regulation of osteoblast differentiation; positive regulation of fat cell differentiation; negative regulation of DNA damage response, signal transduction by p53 class mediator; pigmentation; regulation of tight junction assembly; desmosome disassembly; negative regulation of catenin import into nucleus; positive regulation of histone acetylation; negative regulation of cell adhesion mediated by integrin; regulation of chemokine production; negative regulation of chondrocyte differentiatio | |
| SNAI3 | - | |
| SNAP25 | growth hormone secretion; axonogenesis; endosome transport; synaptic vesicle docking involved in exocytosis; glutamate secretion; long-term memory; sleep; positive regulation of insulin secretion; small molecule metabolic process; positive regulation of hormone secretion; calcium ion-dependent exocytosis of neurotransmitter; regulation of insulin secretion; regulation of synapse assembly; neurotransmitter secretion; synaptic transmission; energy reserve metabolic process; neurotransmitter uptake | |
| SNAP47 | - | |
| SNAPC2 | gene expression; snRNA transcription; transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| SNAPC3 | gene expression; snRNA transcription; transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| SNAPC4 | gene expression; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter; snRNA transcription; transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| SNCA | negative regulation of serotonin uptake; negative regulation of norepinephrine uptake; calcium ion homeostasis; oxidation-reduction process; regulation of excitatory postsynaptic membrane potential; long-term synaptic potentiation; positive regulation of inositol phosphate biosynthetic process; negative regulation of thrombin receptor signaling pathway; response to interleukin-1; cellular response to copper ion; cellular response to epinephrine stimulus; positive regulation of protein serine/threonine kinase activity; response to magnesium ion; cell death; negative regulation of transporter activity; protein destabilization; receptor internalization; negative regulation of microtubule polymerization; regulation of dopamine secretion; regulation of glutamate secretion; negative regulation of platelet-derived growth factor receptor signaling pathway; regulation of phospholipase activity; response to iron(II) ion; adult locomotory behavior; dopamine uptake; mitochondrial membrane organization; activation of cyst | |
| SNCAIP | cell death; dopamine metabolic process; regulation of neurotransmitter secretion; regulation of inclusion body assembly | |
| SNCB | negative regulation of neuron apoptosis; dopamine metabolic process | |
| SNCG | regulation of dopamine secretion; adult locomotory behavior; regulation of neurotransmitter secretion | |
| SND1 | interspecies interaction between organisms; gene silencing by RNA; regulation of transcription, DNA-dependent | |
| SNIP1 | I-kappaB kinase/NF-kappaB cascade; production of miRNAs involved in gene silencing by miRNA; regulation of transcription, DNA-dependent; gene silencing by RNA | |
| SNRNP200 | cis assembly of pre-catalytic spliceosome; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression | |
| SNRNP35 | mRNA processing; RNA splicing | |
| SNRNP48 | RNA splicing; mRNA processing | |
| SNRPA | gene expression; RNA splicing; nuclear mRNA splicing, via spliceosome | |
| SNRPC | spliceosomal snRNP assembly; nuclear mRNA splicing, via spliceosome | |
| SNTA1 | neuromuscular junction development; muscle contraction | |
| SNTB1 | muscle contraction | |
| SNTG1 | cell communication | |
| SNUPN | RNA metabolic process; spliceosomal snRNP assembly; gene expression; ncRNA metabolic process; snRNA import into nucleus; transport; protein import into nucleus | |
| SNX10 | cell communication; endosome organization; protein transport | |
| SNX12 | cell communication; protein transport | |
| SNX14 | cell communication; termination of G-protein coupled receptor signaling pathway; protein transport | |
| SNX17 | cholesterol catabolic process; signal transduction; receptor-mediated endocytosis; endosome transport; intracellular protein transport; regulation of endocytosis | |
| SNX18 | protein transport; positive regulation of GTPase activity; endocytosis; cell communication | |
| SNX19 | cell communication; protein transport | |
| SNX2 | cell communication; endocytosis; intracellular protein transport | |
| SNX20 | protein transport; cell communication | |
| SNX21 | cell communication; protein transport | |
| SNX24 | cell communication; protein transport | |
| SNX25 | termination of G-protein coupled receptor signaling pathway; protein transport; cell communication | |
| SNX30 | protein transport; cell communication | |
| SNX31 | cell communication; protein transport | |
| SNX4 | cell communication; endocytosis; protein transport; endocytic recycling | |
| SNX7 | protein transport; cell communication | |
| SNX9 | positive regulation of GTPase activity; lipid tube assembly; positive regulation of protein oligomerization; cell communication; receptor-mediated endocytosis; intracellular protein transport | |
| SOAT1 | positive regulation of amyloid precursor protein biosynthetic process; steroid metabolic process; cholesterol metabolic process; macrophage derived foam cell differentiation; cholesterol efflux; very-low-density lipoprotein particle assembly; cholesterol homeostasis; cholesterol esterification; cholesterol storage | |
| SOAT2 | steroid metabolic process; cholesterol homeostasis; cholesterol esterification; very-low-density lipoprotein particle assembly; cholesterol efflux; intestinal cholesterol absorption; macrophage derived foam cell differentiation; cholesterol metabolic process | |
| SOBP | inner ear morphogenesis; locomotory behavior; sensory perception of sound | |
| SOCS7 | fat cell differentiation; regulation of growth; intracellular signal transduction; protein ubiquitination; negative regulation of signal transduction; insulin receptor signaling pathway | |
| SOD1 | response to drug; negative regulation of neuron apoptosis; response to hydrogen peroxide; superoxide anion generation; positive regulation of apoptotic process; positive regulation of catalytic activity; transmission of nerve impulse; regulation of multicellular organism growth; regulation of T cell differentiation in thymus; peripheral nervous system myelin maintenance; response to nutrient levels; platelet activation; removal of superoxide radicals; DNA fragmentation involved in apoptotic nuclear change; response to ethanol; negative regulation of cholesterol biosynthetic process; regulation of protein kinase activity; regulation of organ growth; response to copper ion; muscle cell homeostasis; thymus development; response to axon injury; hydrogen peroxide biosynthetic process; regulation of mitochondrial membrane potential; heart contraction; neurofilament cytoskeleton organization; relaxation of vascular smooth muscle; auditory receptor cell stereocilium organization; response to heat; glutathione metabol | |
| SOGA3 | - | |
| SOHLH1 | regulation of transcription, DNA-dependent; multicellular organismal development; spermatogenesis; cell differentiation; oogenesis | |
| SON | spindle pole body separation; microtubule cytoskeleton organization; cytokinesis; mRNA processing; anti-apoptosis; regulation of RNA splicing; regulation of cell cycle | |
| SORBS1 | glucose transport; cellular response to insulin stimulus; stress fiber assembly; positive regulation of lipid biosynthetic process; transport; muscle contraction; positive regulation of glycogen biosynthetic process; positive regulation of glucose import; cell-matrix adhesion; insulin receptor signaling pathway; positive regulation of establishment of protein localization in plasma membrane; focal adhesion assembly | |
| SORBS2 | - | |
| SORBS3 | positive regulation of stress fiber assembly; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cytoskeleton organization; muscle contraction; cell-substrate adhesion; positive regulation of MAPK cascade; cell adhesion | |
| SORCS1 | neuropeptide signaling pathway | |
| SORCS3 | neuropeptide signaling pathway | |
| SORL1 | transport; lipid transport; receptor-mediated endocytosis; steroid metabolic process; cholesterol metabolic process | |
| SORT1 | transport; Golgi to endosome transport; endocytosis; ossification; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; negative regulation of lipoprotein lipase activity; plasma membrane to endosome transport; nerve growth factor receptor signaling pathway; glucose import; negative regulation of apoptotic process; response to insulin stimulus; endosome transport via multivesicular body sorting pathway; cell differentiation; vesicle organization; myotube differentiation; regulation of gene expression; induction of apoptosis by extracellular signals; endosome to lysosome transport; multicellular organismal development | |
| SOS1 | signal transduction; apoptotic process; regulation of small GTPase mediated signal transduction; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction; Ras protein signal transduction; axon guidance; blood coagulation; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; induction of apoptosis by extracellular signals; platelet activation; positive regulation of Rho GTPase activity; regulation of Rho protein signal transduction; nerve growth factor receptor signaling pathway; regulation of catalytic activity; leukocyte migration | |
| SOST | positive regulation of transcription, DNA-dependent; negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; negative regulation of BMP signaling pathway; negative regulation of protein complex assembly; cellular response to parathyroid hormone stimulus; negative regulation of ossification; response to mechanical stimulus; negative regulation of canonical Wnt receptor signaling pathway | |
| SOSTDC1 | negative regulation of BMP signaling pathway; odontogenesis of dentin-containing tooth; Wnt receptor signaling pathway; pattern specification process | |
| SOWAHA | - | |
| SOWAHC | - | |
| SOX1 | regulation of transcription, DNA-dependent; chromatin organization | |
| SOX10 | melanocyte differentiation; negative regulation of canonical Wnt receptor signaling pathway; stem cell differentiation; oligodendrocyte differentiation; developmental growth; digestive tract morphogenesis; enteric nervous system development; cell maturation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; positive regulation of gliogenesis; anatomical structure morphogenesis; peripheral nervous system development; regulation of transcription from RNA polymerase II promoter; positive regulation of neuroblast proliferation; neural crest cell migration; in utero embryonic development | |
| SOX11 | limb bud formation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of hormone secretion; sympathetic nervous system development; embryonic digestive tract morphogenesis; embryonic skeletal system morphogenesis; negative regulation of lymphocyte proliferation; positive regulation of neurogenesis; hard palate development; soft palate development; positive regulation of ossification; negative regulation of glial cell proliferation; ventricular septum morphogenesis; lung morphogenesis; neuroepithelial cell differentiation; eyelid development in camera-type eye; somite development; cornea development in camera-type eye; closure of optic fissure; signal transduction involved in G1/S transition checkpoint; glial cell proliferation; positive regulation of gene expression; positive regulation of cell proliferation; nervous system development; multicellular organismal development; translation; noradrenergic neuron differenti | |
| SOX14 | negative regulation of transcription from RNA polymerase II promoter; nervous system development; negative regulation of transcription, DNA-dependent | |
| SOX17 | regulation of stem cell proliferation; negative regulation of canonical Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; regulation of stem cell division; spermatogenesis; rostrocaudal neural tube patterning; renal system development; regulation of cardiac cell fate specification; negative regulation of Wnt receptor signaling pathway involved in heart development; outflow tract morphogenesis; embryonic heart tube morphogenesis; cardiogenic plate morphogenesis; heart looping; inner cell mass cellular morphogenesis; endoderm formation; vasculogenesis; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; endodermal cell fate determination; positive regulation of cell differentiation; embryonic organ development; embryonic foregut morphogenesis; positive regulation of skeletal muscle tissue development; stem cell differentiation; stem cell fate specification; protein stabilization; endocardium formation; regulation of transcription from RNA polymerase II p | |
| SOX2 | regulation of transcription, DNA-dependent; negative regulation of canonical Wnt receptor signaling pathway; response to growth factor stimulus; negative regulation of epithelial cell proliferation; inner ear development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of neuron differentiation; positive regulation of MAPK cascade; regulation of cysteine-type endopeptidase activity involved in apoptotic process; somatic stem cell maintenance; pituitary gland development; cell cycle arrest; chromatin organization; endodermal cell fate specification; eye development; osteoblast differentiation; multicellular organismal development; response to wounding; regulation of gene expression; glial cell fate commitment; forebrain development | |
| SOX21 | transcription from RNA polymerase II promoter; hair follicle development; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; hair cycle; skin development; stem cell differentiation; negative regulation of neuron differentiation | |
| SOX3 | hypothalamus development; pituitary gland development; forebrain development; negative regulation of neuron differentiation; face development; spermatid differentiation; Sertoli cell development; central nervous system development; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; sex determination; sensory organ development; regulation of transcription, DNA-dependent; multicellular organismal development | |
| SOX30 | transcription from RNA polymerase II promoter; spermatogenesis; response to corticosteroid stimulus; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| SOX5 | cellular response to transforming growth factor beta stimulus; positive regulation of mesenchymal stem cell differentiation; positive regulation of cartilage development; regulation of transcription, DNA-dependent; positive regulation of chondrocyte differentiation; transcription from RNA polymerase II promoter | |
| SOX6 | negative regulation of transcription from RNA polymerase II promoter; muscle organ development; post-embryonic development; cell morphogenesis; in utero embryonic development; regulation of transcription, DNA-dependent; gene silencing; oligodendrocyte cell fate specification; positive regulation of mesenchymal stem cell differentiation; cellular response to transforming growth factor beta stimulus; positive regulation of cartilage development; erythrocyte development; oligodendrocyte differentiation; muscle cell differentiation; cell fate commitment; positive regulation of transcription from RNA polymerase II promoter; cardiac cell differentiation; positive regulation of chondrocyte differentiation; hemopoiesis | |
| SOX9 | positive regulation of epithelial cell proliferation; astrocyte fate commitment; positive regulation of chondrocyte differentiation; Sertoli cell development; Sertoli cell differentiation; cartilage development; negative regulation of epithelial cell proliferation; positive regulation of transcription, DNA-dependent; oligodendrocyte differentiation; negative regulation of apoptotic process; negative regulation of photoreceptor cell differentiation; protein kinase B signaling cascade; regulation of cell differentiation; negative regulation of myoblast differentiation; positive regulation of protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; extracellular matrix organization; negative regulation of chondrocyte differentiation; endocrine pancreas development; otic vesicle formation; notochord development; mammary gland development; positive regulation of epithelial cell differentiation; prostate gland development; | |
| SP1 | regulation of transcription, DNA-dependent; ossification; trophectodermal cell differentiation; liver development; embryonic placenta development; megakaryocyte differentiation; lung development; enucleate erythrocyte differentiation; positive regulation by host of viral transcription; interspecies interaction between organisms; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; embryonic camera-type eye morphogenesis; embryonic skeletal system development; embryonic process involved in female pregnancy; definitive hemopoiesis | |
| SP100 | negative regulation of sequence-specific DNA binding transcription factor activity; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; negative regulation of DNA binding; interspecies interaction between organisms; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; retinoic acid receptor signaling pathway; positive regulation of sequence-specific DNA binding transcription factor activity; negative regulation of cellular component movement; interferon-gamma-mediated signaling pathway; type I interferon-mediated signaling pathway; response to interferon-gamma; response to type I interferon; response to cytokine stimulus; negative regulation of viral transcription; response to retinoic acid; cytokine-mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter | |
| SP140 | regulation of transcription, DNA-dependent; defense response | |
| SP2 | regulation of transcription from RNA polymerase II promoter; immune response | |
| SP3 | regulation of transcription, DNA-dependent; lung development; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; enucleate erythrocyte differentiation; granulocyte differentiation; embryonic camera-type eye morphogenesis; embryonic skeletal system development; embryonic process involved in female pregnancy; definitive hemopoiesis; monocyte differentiation; megakaryocyte differentiation; T cell differentiation; ossification; natural killer cell differentiation; trophectodermal cell differentiation; liver development; embryonic placenta development; B cell differentiation | |
| SP4 | regulation of heart contraction; regulation of transcription from RNA polymerase II promoter | |
| SP6 | positive regulation of cell proliferation; regulation of transcription, DNA-dependent | |
| SP8 | regulation of transcription, DNA-dependent; dorsal/ventral pattern formation; proximal/distal pattern formation; embryonic limb morphogenesis | |
| SPACA1 | - | |
| SPACA3 | cell wall macromolecule catabolic process; positive regulation of macrophage activation; response to virus; positive regulation of phagocytosis; peptidoglycan catabolic process; monocyte activation; defense response to Gram-positive bacterium | |
| SPAG1 | single fertilization | |
| SPAG16 | spermatogenesis; cilium assembly; cell projection organization | |
| SPAG17 | - | |
| SPAG4 | spermatogenesis | |
| SPAG5 | mitotic sister chromatid segregation; mitotic anaphase; cell cycle; spindle organization; chromosome segregation; phosphatidylinositol-mediated signaling; regulation of attachment of spindle microtubules to kinetochore; cell division | |
| SPAG6 | cell projection organization; spermatid development | |
| SPAG8 | - | |
| SPAG9 | striated muscle cell differentiation; positive regulation of muscle cell differentiation; muscle cell differentiation; positive regulation of MAPK cascade; negative regulation of protein homodimerization activity; protein homooligomerization; activation of JUN kinase activity; spermatogenesis; positive regulation of cell migration; retrograde transport, endosome to Golgi; positive regulation of neuron differentiation | |
| SPAM1 | fusion of sperm to egg plasma membrane; binding of sperm to zona pellucida; cell adhesion; carbohydrate metabolic process | |
| SPARCL1 | signal transduction | |
| SPATA13 | cell migration; lamellipodium assembly; regulation of cell migration; regulation of Rho protein signal transduction; filopodium assembly | |
| SPATA16 | cell differentiation; spermatogenesis; multicellular organismal development | |
| SPATA18 | mitochondrial protein catabolic process; cellular response to stress; response to DNA damage stimulus; mitochondrion degradation by induced vacuole formation | |
| SPATA19 | cell differentiation; spermatogenesis; multicellular organismal development | |
| SPATA2 | multicellular organismal development; spermatogenesis; cell differentiation | |
| SPATA21 | - | |
| SPATA22 | - | |
| SPATA2L | - | |
| SPATA31E1 | - | |
| SPATA32 | - | |
| SPATA4 | spermatogenesis; apoptotic process | |
| SPATA5 | multicellular organismal development; cell differentiation; spermatogenesis | |
| SPATA5L1 | - | |
| SPATA6 | spermatogenesis; multicellular organismal development; cell differentiation | |
| SPATA6L | - | |
| SPATA7 | response to stimulus; spermatogenesis; visual perception | |
| SPATC1 | - | |
| SPATC1L | - | |
| SPATS1 | - | |
| SPDL1 | - | |
| SPDYA | G1/S transition of mitotic cell cycle; positive regulation of cyclin-dependent protein kinase activity; positive regulation of cell proliferation; multicellular organismal development; cell cycle; response to DNA damage stimulus | |
| SPDYC | cell cycle | |
| SPECC1 | - | |
| SPECC1L | cell cycle; cell division | |
| SPEF1 | - | |
| SPEF2 | nucleobase-containing compound metabolic process | |
| SPEG | muscle cell differentiation; negative regulation of cell proliferation; muscle organ development | |
| SPEM1 | cell differentiation; multicellular organismal development; spermatogenesis | |
| SPEN | positive regulation of neurogenesis; negative regulation of transcription from RNA polymerase II promoter; Notch signaling pathway; interspecies interaction between organisms; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent | |
| SPERT | - | |
| SPESP1 | multicellular organismal development | |
| SPG11 | cell death | |
| SPG21 | cell death; antigen receptor-mediated signaling pathway | |
| SPG7 | protein catabolic process; cell death; anterograde axon cargo transport; nervous system development; mitochondrion organization; proteolysis | |
| SPHK1 | positive regulation of cell growth; positive regulation of smooth muscle contraction; positive regulation of cell migration; positive regulation of protein ubiquitination; intracellular signal transduction; positive regulation of NF-kappaB import into nucleus; negative regulation of apoptotic process; cellular protein metabolic process; small molecule metabolic process; anti-apoptosis; positive regulation of angiogenesis; positive regulation of fibroblast proliferation; sphingoid catabolic process; positive regulation of mitotic cell cycle; sphingolipid biosynthetic process; calcium-mediated signaling; regulation of tumor necrosis factor-mediated signaling pathway; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; signal transduction; sphingosine metabolic process; sphingolipid metabolic process; protein folding; 'de novo' posttranslational protein folding; positive regulation of NF-kappaB transcription factor activity | |
| SPHK2 | sphingolipid metabolic process; blood vessel development; anti-apoptosis; sphinganine-1-phosphate biosynthetic process; cell proliferation; sphingosine metabolic process; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; sphingolipid biosynthetic process; small molecule metabolic process; brain development; positive regulation of cell proliferation | |
| SPHKAP | - | |
| SPI1 | negative regulation of transcription, DNA-dependent; negative regulation of gene expression, epigenetic; negative regulation of transcription from RNA polymerase II promoter; histone H3 acetylation; hypermethylation of CpG island; regulation of erythrocyte differentiation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of histone H4 acetylation | |
| SPIDR | - | |
| SPIN1 | multicellular organismal development; cell cycle; gamete generation | |
| SPINK1 | negative regulation of endopeptidase activity | |
| SPINK5 | extracellular matrix organization; epithelial cell differentiation; hair cell differentiation; anagen; negative regulation of angiogenesis; regulation of T cell differentiation; epidermal cell differentiation; negative regulation of immune response | |
| SPINK6 | - | |
| SPINK9 | negative regulation of proteolysis | |
| SPINT1 | placenta blood vessel development; branching involved in embryonic placenta morphogenesis; extracellular matrix organization; embryonic placenta development | |
| SPIRE1 | transport | |
| SPNS1 | lipid transport; transmembrane transport | |
| SPNS3 | transmembrane transport; lipid transport | |
| SPO11 | male meiosis I; spermatogenesis; spermatid development; female gamete generation; protein localization to chromosome; reciprocal meiotic recombination; meiosis; ovarian follicle development; zygotene; DNA metabolic process | |
| SPOCD1 | transcription, DNA-dependent; negative regulation of phosphatase activity | |
| SPOCK1 | neurogenesis; regulation of cell growth; neuron migration; cell adhesion; signal transduction; nervous system development; negative regulation of cell-substrate adhesion; negative regulation of endopeptidase activity; negative regulation of neuron projection development; central nervous system neuron differentiation | |
| SPOCK2 | signal transduction; positive regulation of cell-substrate adhesion; regulation of cell differentiation; extracellular matrix organization; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; synapse assembly | |
| SPOCK3 | negative regulation of endopeptidase activity; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; signal transduction | |
| SPON2 | innate immune response; axon guidance; cell adhesion | |
| SPP1 | positive regulation of cell-substrate adhesion; response to organic substance; biomineral tissue development; response to vitamin D; positive regulation of bone resorption; decidualization; response to steroid hormone stimulus; negative regulation of collateral sprouting of intact axon in response to injury; inflammatory response; osteoblast differentiation; ossification; embryo implantation; cell adhesion | |
| SPRTN | - | |
| SPRY4 | negative regulation of MAP kinase activity; regulation of signal transduction; multicellular organismal development | |
| SPSB1 | intracellular signal transduction | |
| SPSB4 | intracellular signal transduction | |
| SPTA1 | actin filament organization; porphyrin-containing compound biosynthetic process; axon guidance; regulation of cell shape; hemopoiesis; actin filament capping | |
| SPTAN1 | apoptotic process; cellular component disassembly involved in apoptosis; axon guidance; actin filament capping | |
| SPTB | axon guidance; actin filament capping | |
| SPTBN1 | axon guidance; actin filament capping; common-partner SMAD protein phosphorylation; SMAD protein import into nucleus | |
| SPTBN2 | axon guidance; cell death; vesicle-mediated transport; actin filament capping | |
| SPTBN4 | sensory perception of sound; vesicle-mediated transport; transmission of nerve impulse; fertilization; cytoskeletal anchoring at plasma membrane; actin filament capping; axon guidance; adult walking behavior; positive regulation of multicellular organism growth; adult behavior | |
| SPTLC1 | sphingomyelin biosynthetic process; biosynthetic process; sphingolipid metabolic process; sphingolipid biosynthetic process; small molecule metabolic process; sphinganine biosynthetic process; sphingosine biosynthetic process | |
| SPTLC2 | small molecule metabolic process; sphingolipid biosynthetic process; biosynthetic process; sphingomyelin biosynthetic process; sphingolipid metabolic process; sphinganine biosynthetic process; sphingosine biosynthetic process | |
| SPTLC3 | biosynthetic process; sphingolipid biosynthetic process; small molecule metabolic process; sphingoid biosynthetic process; sphingolipid metabolic process | |
| SPTSSA | sphingolipid biosynthetic process | |
| SPTY2D1 | - | |
| SPX | - | |
| SPZ1 | regulation of transcription, DNA-dependent | |
| SQRDL | sulfur amino acid catabolic process; cellular nitrogen compound metabolic process; sulfur amino acid metabolic process; small molecule metabolic process; sulfide oxidation, using sulfide:quinone oxidoreductase | |
| SRA1 | regulation of transcription, DNA-dependent; apoptotic process; cell proliferation; cell differentiation; positive regulation of transcription from RNA polymerase II promoter | |
| SRC | leukocyte migration; uterus development; branching involved in mammary gland duct morphogenesis; positive regulation of ERK1 and ERK2 cascade; response to interleukin-1; positive regulation of canonical Wnt receptor signaling pathway; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of intrinsic apoptotic signaling pathway; cell adhesion; cell cycle; oogenesis; protein phosphorylation; nerve growth factor receptor signaling pathway; signal transduction; signal complex assembly; epidermal growth factor receptor signaling pathway; intracellular protein kinase cascade; Ras protein signal transduction; axon guidance; blood coagulation; fibroblast growth factor receptor signaling pathway; cellular membrane organization; phosphorylation; peptidyl-tyrosine phosphorylation; platelet activation; forebrain development; T cell costimulation; regulation of intracellular estrogen receptor signaling pathway; positive regulation of integrin activation; regulation of vascular permeability; in | |
| SRCAP | histone acetylation; interspecies interaction between organisms; regulation of transcription from RNA polymerase II promoter; chromatin modification | |
| SREBF1 | regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; lipid metabolic process; steroid metabolic process; cholesterol metabolic process; cellular response to starvation; positive regulation of triglyceride biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; lipid biosynthetic process | |
| SREBF2 | positive regulation of transcription from RNA polymerase II promoter; negative regulation of cholesterol efflux; regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter; cellular response to laminar fluid shear stress; response to low-density lipoprotein particle stimulus; response to drug; positive regulation of transcription via sterol regulatory element binding; response to lipid; response to lead ion; response to hormone stimulus; cholesterol metabolic process; steroid metabolic process; aging; spermatogenesis; lipid metabolic process; positive regulation of cholesterol storage | |
| SRGAP1 | signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; Rho protein signal transduction; axon guidance; cell migration | |
| SRGAP3 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction | |
| SRL | - | |
| SRM | spermidine biosynthetic process; small molecule metabolic process; cellular nitrogen compound metabolic process; polyamine metabolic process | |
| SRP19 | translation; cotranslational protein targeting to membrane; SRP-dependent cotranslational protein targeting to membrane; gene expression; cellular protein metabolic process; response to drug | |
| SRP54 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; GTP catabolic process; translation; SRP-dependent cotranslational protein targeting to membrane; SRP-dependent cotranslational protein targeting to membrane, translocation; gene expression; response to drug; cellular protein metabolic process; protein targeting to ER | |
| SRPK2 | positive regulation of neuron apoptosis; RNA splicing; positive regulation of cell proliferation; intracellular protein kinase cascade; protein phosphorylation; positive regulation of gene expression; innate immune response; positive regulation of cell cycle; regulation of nuclear mRNA splicing, via spliceosome; negative regulation of viral genome replication; positive regulation of viral genome replication; mRNA processing; angiogenesis; spliceosome assembly; cell differentiation; nuclear speck organization | |
| SRPK3 | muscle tissue development; cell differentiation; skeletal muscle tissue development; protein phosphorylation; muscle organ development; multicellular organismal development | |
| SRPX | cell adhesion | |
| SRRM1 | transcription from RNA polymerase II promoter; gene expression; termination of RNA polymerase II transcription; mRNA export from nucleus; RNA splicing; mRNA 3'-end processing; nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions | |
| SRRM2 | nuclear mRNA splicing, via spliceosome; RNA splicing | |
| SRRT | response to arsenic-containing substance; cell proliferation; gene silencing by RNA; primary miRNA processing | |
| SRSF5 | termination of RNA polymerase II transcription; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA 3'-end processing; gene expression; RNA splicing; mRNA export from nucleus; mRNA processing; mRNA splice site selection | |
| SRXN1 | response to oxidative stress | |
| SS18 | response to drug; intracellular protein kinase cascade; regulation of transcription, DNA-dependent; cell morphogenesis; microtubule cytoskeleton organization; ephrin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter | |
| SSBP3 | protein complex assembly; positive regulation of anterior head development; positive regulation of cell proliferation; prechordal plate formation; midbrain-hindbrain boundary initiation; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; head morphogenesis | |
| SSC4D | - | |
| SSFA2 | - | |
| SSH2 | regulation of actin polymerization or depolymerization; protein dephosphorylation; regulation of axonogenesis; actin cytoskeleton organization; regulation of lamellipodium assembly | |
| SSH3 | regulation of actin polymerization or depolymerization; protein dephosphorylation; regulation of lamellipodium assembly; regulation of axonogenesis | |
| SSR4 | SRP-dependent cotranslational protein targeting to membrane; translation; intracellular protein transport; gene expression; cellular protein metabolic process | |
| SSRP1 | transcription elongation from RNA polymerase II promoter; positive regulation of viral transcription; viral reproduction; DNA replication; DNA repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; gene expression | |
| SST | cell-cell signaling; response to steroid hormone stimulus; response to amino acid stimulus; response to drug; response to organic nitrogen; hyperosmotic response; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; synaptic transmission; response to nutrient; digestion; negative regulation of cell proliferation; induction of apoptosis by hormones; response to heat; regulation of cell migration | |
| SSTR1 | digestion; cell surface receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; glutamate receptor signaling pathway; neuropeptide signaling pathway; cell-cell signaling; response to nutrient; negative regulation of cell proliferation | |
| SSTR4 | G-protein coupled receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cell proliferation | |
| SSUH2 | - | |
| SSX2IP | cell adhesion | |
| ST14 | proteolysis | |
| ST18 | negative regulation of transcription from RNA polymerase II promoter | |
| ST3GAL3 | protein glycosylation; O-glycan processing; post-translational protein modification; cellular protein metabolic process | |
| ST3GAL4 | protein glycosylation; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; O-glycan processing | |
| ST3GAL5 | glycosphingolipid biosynthetic process; protein glycosylation; carbohydrate metabolic process; ganglioside biosynthetic process | |
| ST3GAL6 | cellular response to interleukin-6; oligosaccharide metabolic process; glycolipid metabolic process; protein glycosylation; protein modification process | |
| ST5 | positive regulation of ERK1 and ERK2 cascade | |
| ST6GAL2 | oligosaccharide metabolic process; protein glycosylation; growth; multicellular organismal development | |
| ST6GALNAC1 | protein glycosylation | |
| ST6GALNAC3 | protein glycosylation; glycosylceramide metabolic process; glycosphingolipid metabolic process; glycoprotein metabolic process | |
| ST6GALNAC6 | ganglioside biosynthetic process; protein glycosylation; glycosylceramide metabolic process; glycosphingolipid metabolic process; glycoprotein metabolic process; oligosaccharide biosynthetic process; cell-cell recognition | |
| ST7 | - | |
| ST8SIA1 | protein glycosylation; sphingolipid metabolic process; lipid metabolic process; carbohydrate metabolic process; glycosphingolipid biosynthetic process; cellular response to heat; positive regulation of cell proliferation | |
| ST8SIA2 | post-translational protein modification; protein N-linked glycosylation via asparagine; cellular protein metabolic process; ganglioside biosynthetic process; carbohydrate metabolic process; protein modification process; protein glycosylation; N-glycan processing; nervous system development; axon guidance; oligosaccharide metabolic process | |
| ST8SIA3 | post-translational protein modification; ganglioside biosynthetic process; protein glycosylation; N-glycan processing; glycosphingolipid biosynthetic process; glycoprotein metabolic process; cellular protein metabolic process; oligosaccharide metabolic process; protein N-linked glycosylation via asparagine | |
| ST8SIA4 | axon guidance; oligosaccharide metabolic process; nervous system development; N-glycan processing; protein glycosylation; protein modification process; ganglioside biosynthetic process | |
| ST8SIA6 | oligosaccharide metabolic process; ganglioside biosynthetic process; protein O-linked glycosylation; glycoprotein metabolic process; glycolipid biosynthetic process; carbohydrate biosynthetic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process | |
| STAB1 | receptor-mediated endocytosis; defense response to bacterium; inflammatory response; cell adhesion; cell-cell signaling; negative regulation of angiogenesis | |
| STAB2 | defense response to bacterium; cell adhesion; angiogenesis; endocytosis; receptor-mediated endocytosis | |
| STAC2 | intracellular signal transduction | |
| STAG1 | chromosome segregation; mitotic metaphase/anaphase transition; mitotic cell cycle; mitotic prometaphase; cell division; M phase of mitotic cell cycle | |
| STAG2 | sister chromatid cohesion; cell division; M phase of mitotic cell cycle; negative regulation of DNA endoreduplication; mitotic prometaphase; mitotic cell cycle; meiosis; mitotic metaphase/anaphase transition | |
| STAG3 | chromosome segregation; synaptonemal complex assembly; meiosis; cell cycle | |
| STAM | negative regulation of epidermal growth factor receptor signaling pathway; intracellular protein transport; signal transduction; epidermal growth factor receptor signaling pathway; cellular membrane organization; endosome transport | |
| STAM2 | intracellular protein transport; negative regulation of epidermal growth factor receptor signaling pathway; endosome transport; cellular membrane organization; epidermal growth factor receptor signaling pathway | |
| STAMBP | proteolysis; anti-apoptosis; positive regulation of cell proliferation; JAK-STAT cascade | |
| STAMBPL1 | proteolysis | |
| STAP1 | signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; cellular membrane fusion; intracellular protein transport | |
| STAP2 | - | |
| STAR | steroid biosynthetic process; steroid metabolic process; C21-steroid hormone biosynthetic process; transport; lipid transport; regulation of steroid biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; glucocorticoid metabolic process | |
| STARD13 | regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction | |
| STARD3 | cholesterol metabolic process; steroid metabolic process; lipid transport; mitochondrial transport; transport; steroid biosynthetic process; lipid metabolic process | |
| STARD3NL | - | |
| STARD5 | steroid metabolic process; lipid transport; transport; C21-steroid hormone biosynthetic process; small molecule metabolic process | |
| STARD8 | regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction | |
| STAT1 | type I interferon-mediated signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; response to cytokine stimulus; tumor necrosis factor-mediated signaling pathway; response to lipopolysaccharide; lipopolysaccharide-mediated signaling pathway; cytokine-mediated signaling pathway; negative regulation of angiogenesis; response to bacterium; response to virus; positive regulation of transcription from RNA polymerase II promoter; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; regulation of transcription from RNA polymerase II promoter; induction of apoptosis; regulation of type I interferon-mediated signaling pathway; JAK-STAT cascade involved in growth hormone signaling pathway; renal tubule development; negative regulation of metanephric nephron tubule epithelial cell differentiation; JAK-STAT cascade; blood circulation; metanephric mesenchymal cell differentiation; negative regulation of transcription from | |
| STAT2 | response to virus; cytokine-mediated signaling pathway; interspecies interaction between organisms; type I interferon-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway; JAK-STAT cascade; regulation of transcription from RNA polymerase II promoter | |
| STAT4 | cytokine-mediated signaling pathway; cell proliferation; JAK-STAT cascade; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; protein phosphorylation | |
| STAT5B | positive regulation of inflammatory response; response to interleukin-2; fatty acid metabolic process; acute-phase response; JAK-STAT cascade; sex differentiation; female pregnancy; lactation; regulation of steroid metabolic process; cytokine-mediated signaling pathway; taurine metabolic process; lipid storage; regulation of transcription from RNA polymerase II promoter; allantoin metabolic process; luteinization; response to hypoxia; liver development; citrate metabolic process; 2-oxoglutarate metabolic process; succinate metabolic process; oxaloacetate metabolic process; positive regulation of cellular component movement; isoleucine metabolic process; valine metabolic process; creatine metabolic process; response to interleukin-15; response to interleukin-4; negative regulation of apoptotic process; JAK-STAT cascade involved in growth hormone signaling pathway; positive regulation of B cell differentiation; regulation of multicellular organism growth; positive regulation of interleukin-2 biosynthetic proces | |
| STAT6 | positive regulation of transcription from RNA polymerase II promoter; positive regulation of isotype switching to IgE isotypes; regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; response to cytokine stimulus; cytokine-mediated signaling pathway; signal transduction; negative regulation of type 2 immune response; negative regulation of transcription from RNA polymerase II promoter | |
| STAU1 | intracellular mRNA localization | |
| STC2 | cell surface receptor signaling pathway; cell-cell signaling; embryo implantation; response to nutrient; response to vitamin D; response to peptide hormone stimulus; decidualization; cellular response to hypoxia | |
| STEAP2 | iron ion homeostasis; ion transport; Golgi to plasma membrane transport; endocytosis; response to hormone stimulus; electron transport chain; regulated secretory pathway | |
| STEAP3 | cell cycle; apoptotic process; cellular iron ion homeostasis; ion transport; protein secretion; transferrin transport; transmembrane transport | |
| STEAP4 | ion transport; iron ion homeostasis; fat cell differentiation | |
| STIL | neural tube development; forebrain development; embryonic axis specification; in utero embryonic development; neural tube closure; heart looping; smoothened signaling pathway; multicellular organismal development; determination of left/right symmetry; negative regulation of apoptotic process; multicellular organism growth; floor plate development; notochord development; cell proliferation | |
| STIM1 | detection of calcium ion; cation transport; blood coagulation; activation of store-operated calcium channel activity; regulation of calcium ion transport | |
| STIM2 | positive regulation of calcium ion transport; activation of store-operated calcium channel activity; negative regulation of calcium ion transport via store-operated calcium channel activity; ion transport; cellular calcium ion homeostasis | |
| STIP1 | axon guidance; response to stress | |
| STK10 | regulation of lymphocyte migration; protein autophosphorylation; lymphocyte aggregation; cell cycle; protein phosphorylation | |
| STK25 | Golgi localization; response to oxidative stress; protein phosphorylation; positive regulation of axonogenesis; signal transduction; establishment or maintenance of cell polarity | |
| STK26 | - | |
| STK31 | - | |
| STK32C | - | |
| STK33 | protein autophosphorylation | |
| STK35 | - | |
| STK36 | regulation of sequence-specific DNA binding transcription factor activity; positive regulation of smoothened signaling pathway; cilium assembly; cell projection organization; protein phosphorylation; positive regulation of hh target transcription factor activity; post-embryonic development | |
| STK38 | intracellular protein kinase cascade; protein phosphorylation; protein modification process; negative regulation of MAP kinase activity | |
| STK39 | response to stress; protein phosphorylation; signal transduction by phosphorylation; positive regulation of potassium ion transport | |
| STK4 | cell differentiation involved in embryonic placenta development; positive regulation of protein serine/threonine kinase activity; negative regulation of canonical Wnt receptor signaling pathway; induction of apoptosis; protein phosphorylation; endocardium development; neural tube formation; patterning of blood vessels; cell morphogenesis; primitive hemopoiesis; protein autophosphorylation; negative regulation of organ growth; positive regulation of apoptotic process; hippo signaling cascade; keratinocyte differentiation; peptidyl-serine phosphorylation; negative regulation of cell proliferation; central nervous system development; intracellular protein kinase cascade; signal transduction | |
| STK40 | - | |
| STKLD1 | - | |
| STMN2 | positive regulation of neuron projection development; negative regulation of neuron projection development; positive regulation of microtubule depolymerization; negative regulation of microtubule depolymerization; negative regulation of microtubule polymerization; intracellular signal transduction; neuron differentiation | |
| STMN4 | intracellular signal transduction | |
| STOM | protein homooligomerization | |
| STOML2 | - | |
| STOML3 | signal transduction | |
| STON2 | intracellular protein transport; regulation of endocytosis | |
| STOX1 | - | |
| STPG2 | - | |
| STRA6 | digestive tract morphogenesis; vocal learning; kidney development; blood vessel development; ear development; pulmonary valve morphogenesis; positive regulation of behavior; ventricular septum development; transport; heart development; female genitalia development; learning; adrenal gland development; lung alveolus development; feeding behavior; nose morphogenesis; lung development; cognition; eyelid development in camera-type eye; embryonic camera-type eye formation; uterus morphogenesis; diaphragm development; lung vasculature development; face morphogenesis; head morphogenesis; head development; neuromuscular process; artery morphogenesis; smooth muscle tissue development; developmental growth; embryonic digestive tract development; alveolar primary septum development; pulmonary artery morphogenesis; paramesonephric duct development | |
| STRA8 | meiosis; regulation of organ growth; meiotic DNA double-strand break formation; meiotic cell cycle DNA replication checkpoint; oocyte development; meiotic chromosome condensation; DNA replication; fertilization; spermatogenesis; reciprocal meiotic recombination; synapsis; female meiosis sister chromatid cohesion; cellular response to retinoic acid; ovarian follicle development | |
| STRADA | positive regulation of protein phosphorylation; cell cycle arrest; cell cycle; protein heterooligomerization; regulation of fatty acid oxidation; activation of protein kinase activity; insulin receptor signaling pathway; protein phosphorylation; protein export from nucleus | |
| STRBP | spermatogenesis; cellular component movement; multicellular organismal development; mechanosensory behavior; spermatid development; cell differentiation | |
| STRIP1 | - | |
| STRIP2 | - | |
| STRN | dendrite development; locomotory behavior; tight junction assembly; Wnt receptor signaling pathway; negative regulation of cell proliferation | |
| STRN4 | - | |
| STS | small molecule metabolic process; response to organic cyclic compound; response to pH; epidermis development; positive regulation of cell proliferation; learning or memory; female pregnancy; steroid catabolic process; glycosphingolipid metabolic process; sphingolipid metabolic process; response to peptide hormone stimulus; skin development; response to estrogen stimulus | |
| STT3A | cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; protein glycosylation | |
| STT3B | protein N-linked glycosylation via asparagine; protein glycosylation | |
| STX11 | cellular membrane fusion; intracellular protein transport; vesicle-mediated transport | |
| STX17 | vesicle-mediated transport; intracellular protein transport | |
| STX18 | vesicle-mediated transport; ER to Golgi vesicle-mediated transport; intracellular protein transport | |
| STX1B | neurotransmitter transport; transport; regulation of exocytosis; intracellular protein transport; synaptic transmission; vesicle-mediated transport | |
| STX2 | cytokinetic cell separation; digestive tract morphogenesis; plasma membrane fusion; epithelial cell differentiation; microvillus assembly; vesicle-mediated transport; organ morphogenesis; ectoderm development; acrosome reaction; signal transduction; intracellular protein transport; cytokinesis | |
| STX3 | cellular response to oxidative stress; neurotransmitter transport; neuron projection development; intracellular protein transport; exocytosis; cellular membrane fusion | |
| STX6 | vesicle fusion; endosome organization; retrograde transport, endosome to Golgi; Golgi vesicle transport; intracellular protein transport | |
| STXBP2 | neutrophil degranulation; regulation of mast cell degranulation; protein transport; response to acidity; vesicle docking involved in exocytosis; leukocyte mediated cytotoxicity | |
| STXBP3 | vesicle docking involved in exocytosis; blood coagulation; protein transport; vesicle-mediated transport; platelet activation; neutrophil degranulation; negative regulation of calcium ion-dependent exocytosis; platelet aggregation | |
| STXBP4 | protein targeting; insulin receptor signaling pathway; glucose transport | |
| STXBP5 | protein transport; positive regulation of exocytosis | |
| STXBP5L | protein transport; exocytosis | |
| STYK1 | - | |
| SUCLA2 | succinate metabolic process; succinyl-CoA metabolic process; tricarboxylic acid cycle; succinyl-CoA pathway; small molecule metabolic process | |
| SUCLG1 | small molecule metabolic process; tricarboxylic acid cycle; succinyl-CoA metabolic process; succinate metabolic process | |
| SUCLG2 | tricarboxylic acid cycle; succinyl-CoA metabolic process; small molecule metabolic process | |
| SUCO | - | |
| SUGP1 | gene expression; nuclear mRNA splicing, via spliceosome; RNA splicing | |
| SUGP2 | RNA splicing; mRNA processing | |
| SUGT1 | mitosis; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; innate immune response | |
| SULF1 | innervation; positive regulation of Wnt receptor signaling pathway; negative regulation of prostatic bud formation; positive regulation vascular endothelial growth factor production; negative regulation of angiogenesis; bone development; vascular endothelial growth factor receptor signaling pathway; cartilage development; negative regulation of cell migration; heparan sulfate proteoglycan metabolic process; glomerular filtration; kidney development; embryonic skeletal system development; chondrocyte development; negative regulation of endothelial cell proliferation; regulation of fibroblast growth factor receptor signaling pathway; negative regulation of fibroblast growth factor receptor signaling pathway; glial cell-derived neurotrophic factor receptor signaling pathway; esophagus smooth muscle contraction; glomerular basement membrane development; positive regulation of BMP signaling pathway; apoptotic process | |
| SULF2 | esophagus smooth muscle contraction; positive regulation of Wnt receptor signaling pathway; heparan sulfate proteoglycan metabolic process; chondrocyte development; glial cell-derived neurotrophic factor receptor signaling pathway; glomerular basement membrane development; positive regulation vascular endothelial growth factor production; negative regulation of fibroblast growth factor receptor signaling pathway; glomerular filtration; embryonic skeletal system development; kidney development; bone development; cartilage development; innervation | |
| SULT1E1 | xenobiotic metabolic process; female pregnancy; steroid metabolic process; estrogen metabolic process; small molecule metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; sulfation | |
| SUN1 | cytoskeletal anchoring at nuclear membrane; nuclear matrix anchoring at nuclear membrane | |
| SUN2 | centrosome localization; cytoskeletal anchoring at nuclear membrane; nuclear matrix anchoring at nuclear membrane; nuclear migration along microfilament; positive regulation of cell migration; nuclear migration; mitotic spindle organization; nuclear envelope organization | |
| SUN3 | - | |
| SUN5 | spermatogenesis | |
| SUOX | response to nutrient; sulfur amino acid catabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process; sulfide oxidation, using sulfide:quinone oxidoreductase; sulfur amino acid metabolic process | |
| SUPT16H | viral reproduction; positive regulation of transcription elongation, DNA-dependent; DNA repair; nucleosome disassembly; gene expression; regulation of transcription, DNA-dependent; DNA replication; transcription elongation from RNA polymerase II promoter; cellular process; transcription from RNA polymerase II promoter; positive regulation of viral transcription | |
| SUPT20H | - | |
| SUPT3H | transcription from RNA polymerase II promoter; histone H3 acetylation; histone deubiquitination; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription initiation, DNA-dependent | |
| SUPT5H | negative regulation of transcription from RNA polymerase II promoter; chromatin remodeling; transcription elongation, DNA-dependent; transcription elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; mRNA capping; cell cycle; response to organic substance; gene expression; viral reproduction; positive regulation of viral transcription; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription elongation, DNA-dependent; positive regulation of transcription elongation, DNA-dependent; positive regulation of transcription elongation from RNA polymerase II promoter; retroviral genome replication | |
| SUPT6H | chromatin remodeling; nucleobase-containing compound metabolic process; regulation of transcription elongation, DNA-dependent; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| SUPT7L | histone H3 acetylation; regulation of transcription, DNA-dependent; maintenance of protein location in nucleus | |
| SUPV3L1 | positive regulation of cell growth; DNA duplex unwinding; mitochondrial RNA 3'-end processing; positive regulation of mitochondrial RNA catabolic process; mitochondrial mRNA catabolic process; DNA recombination; RNA catabolic process; anti-apoptosis; mitochondrial RNA surveillance; chromatin maintenance; mitochondrion morphogenesis; mitochondrial mRNA surveillance; mitochondrial ncRNA surveillance | |
| SURF6 | ribosome biogenesis | |
| SUSD1 | - | |
| SUSD2 | immune response | |
| SUSD3 | - | |
| SUSD4 | - | |
| SUSD6 | - | |
| SUZ12 | negative regulation of transcription from RNA polymerase II promoter; histone methylation; positive regulation of cell proliferation; histone ubiquitination; negative regulation of cell differentiation; chromatin modification; regulation of transcription, DNA-dependent | |
| SV2A | neurotransmitter transport; cellular calcium ion homeostasis | |
| SV2B | neurotransmitter transport | |
| SV2C | neurotransmitter transport | |
| SVIL | cytoskeleton organization; skeletal muscle tissue development | |
| SVOPL | - | |
| SWT1 | - | |
| SYCE1 | meiotic prophase I; cell cycle; meiosis; cell division | |
| SYCE2 | cell cycle; cell division; meiotic prophase I; meiosis | |
| SYCP1 | regulation of protein localization; spermatogenesis; reciprocal meiotic recombination; synaptonemal complex assembly; meiosis; cell cycle; cell division | |
| SYCP2 | cell cycle; synaptonemal complex assembly; cell division; meiotic prophase I; meiosis | |
| SYCP2L | - | |
| SYCP3 | cell division; spermatogenesis, exchange of chromosomal proteins; male meiosis I; meiosis; cell cycle | |
| SYDE1 | signal transduction; small GTPase mediated signal transduction; activation of Rho GTPase activity; regulation of small GTPase mediated signal transduction | |
| SYF2 | RNA splicing; nuclear mRNA splicing, via spliceosome | |
| SYK | angiogenesis; regulation of platelet aggregation; regulation of arachidonic acid secretion; activation of JUN kinase activity; defense response to bacterium; intracellular signal transduction; positive regulation of cell adhesion mediated by integrin; regulation of superoxide anion generation; neutrophil chemotaxis; platelet activation; leukotriene biosynthetic process; regulation of platelet activation; organ morphogenesis; cell proliferation; blood coagulation; regulation of ERK1 and ERK2 cascade; integrin-mediated signaling pathway; enzyme linked receptor protein signaling pathway; leukocyte cell-cell adhesion; protein phosphorylation; serotonin secretion by platelet; leukocyte activation involved in immune response; neutrophil activation involved in immune response; macrophage activation involved in immune response; adaptive immune response; lymph vessel development; serotonin secretion; regulation of neutrophil degranulation; cellular response to molecule of fungal origin; B cell receptor signaling pathw | |
| SYMPK | mRNA processing; cell adhesion | |
| SYN1 | transport; neurotransmitter secretion; synaptic transmission | |
| SYN3 | neurotransmitter secretion | |
| SYNC | intermediate filament-based process | |
| SYNCRIP | interspecies interaction between organisms; nuclear mRNA splicing, via spliceosome; RNA splicing; RNA processing; CRD-mediated mRNA stabilization | |
| SYNDIG1 | intracellular protein transport; response to biotic stimulus; positive regulation of synapse assembly; synaptic vesicle clustering | |
| SYNDIG1L | response to biotic stimulus | |
| SYNE1 | nuclear matrix anchoring at nuclear membrane; cytoskeletal anchoring at nuclear membrane; nucleus organization; muscle cell differentiation; cell death; Golgi organization | |
| SYNE2 | nuclear migration along microfilament; centrosome localization; nuclear migration; positive regulation of cell migration; cytoskeletal anchoring at nuclear membrane | |
| SYNE3 | - | |
| SYNGR1 | protein targeting; regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity | |
| SYNGR4 | - | |
| SYNJ1 | neurotransmitter transport; synaptic vesicle endocytosis; positive regulation of receptor-mediated endocytosis; phosphatidylinositol dephosphorylation; phosphatidylinositol phosphorylation; response to cytokine stimulus; phosphate-containing compound metabolic process; brain development; learning; positive regulation of gliogenesis; synaptic vesicle priming; synaptic vesicle uncoating; response to retinoic acid | |
| SYNJ2 | intracellular distribution of mitochondria; brain development; phosphatidylinositol phosphorylation; inositol phosphate dephosphorylation; phosphatidylinositol dephosphorylation | |
| SYNPO | positive regulation of actin filament bundle assembly; regulation of stress fiber assembly | |
| SYNPO2 | - | |
| SYNPO2L | - | |
| SYNRG | endocytosis; intracellular protein transport | |
| SYPL1 | synaptic transmission | |
| SYPL2 | cellular calcium ion homeostasis | |
| SYT1 | glutamate secretion; synaptic vesicle exocytosis; regulation of exocytosis; regulation of calcium ion-dependent exocytosis; protein homooligomerization; synaptic transmission; detection of calcium ion; neurotransmitter secretion | |
| SYT12 | - | |
| SYT17 | - | |
| SYT2 | neurotransmitter secretion; synaptic transmission | |
| SYT3 | - | |
| SYT4 | neurotransmitter secretion | |
| SYT6 | acrosomal vesicle exocytosis | |
| SYT9 | regulation of insulin secretion; regulation of calcium ion-dependent exocytosis | |
| SYTL1 | intracellular protein transport; exocytosis; vesicle-mediated transport | |
| SYTL2 | vesicle-mediated transport; negative regulation of phosphatase activity; intracellular protein transport; vesicle docking involved in exocytosis; exocytosis | |
| SYTL3 | intracellular protein transport | |
| SYTL5 | intracellular protein transport | |
| SYVN1 | in utero embryonic development; endoplasmic reticulum unfolded protein response; response to stress; anti-apoptosis; ER-associated protein catabolic process; activation of signaling protein activity involved in unfolded protein response | |
| SZT2 | post-embryonic development; central nervous system development; pigmentation | |
| T | cardiac muscle cell differentiation; tail morphogenesis; reproductive process; BMP signaling pathway; notochord development; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; primitive streak formation; SMAD protein signal transduction; canonical Wnt receptor signaling pathway; vasculogenesis; somitogenesis; neural plate morphogenesis; neural tube closure; heart morphogenesis; signal transduction involved in regulation of gene expression; regulation of transcription, DNA-dependent; signal transduction; multicellular organismal development; mesoderm development; positive regulation of cell proliferation; anterior/posterior axis specification, embryo | |
| TAAR1 | G-protein coupled receptor signaling pathway | |
| TAAR5 | synaptic transmission; signal transduction; G-protein coupled receptor signaling pathway | |
| TAAR6 | G-protein coupled receptor signaling pathway | |
| TAAR8 | G-protein coupled receptor signaling pathway | |
| TAB2 | innate immune response; activation of MAPK activity; toll-like receptor 4 signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; I-kappaB kinase/NF-kappaB cascade; positive regulation of NF-kappaB transcription factor activity; stress-activated MAPK cascade; toll-like receptor signaling pathway; nucleotide-binding oligomerization domain containing signaling pathway; toll-like receptor 2 signaling pathway; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; positive regulation of protein kinase activity; T cell receptor signaling pathway; Toll signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; toll-like receptor 1 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; heart development; JNK cascade | |
| TAB3 | activation of MAPK activity; toll-like receptor 4 signaling pathway; MyD88-independent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; nucleotide-binding oligomerization domain containing signaling pathway; stress-activated MAPK cascade; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; I-kappaB kinase/NF-kappaB cascade; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; Toll signaling pathway; innate immune response; toll-like receptor 1 signaling pathway; JNK cascade | |
| TACC2 | interkinetic nuclear migration; astral microtubule organization; cell proliferation; microtubule cytoskeleton organization; regulation of microtubule-based process; neurogenesis; cerebral cortex development | |
| TACC3 | neurogenesis; cell proliferation; regulation of microtubule-based process; cytoplasmic sequestering of transcription factor; regulation of cell cycle; response to stress; cerebral cortex development; hemopoiesis; astral microtubule organization; microtubule cytoskeleton organization; interkinetic nuclear migration | |
| TACO1 | regulation of translation | |
| TACR1 | positive regulation of synaptic transmission, cholinergic; response to ozone; positive regulation of synaptic transmission, GABAergic; response to nicotine; operant conditioning; positive regulation of renal sodium excretion; behavioral response to pain; sperm ejaculation; positive regulation of vasoconstriction; positive regulation of blood pressure; positive regulation of action potential; response to ethanol; response to morphine; eating behavior; sensory perception of pain; response to auditory stimulus; positive regulation of epithelial cell migration; behavior; response to hormone stimulus; detection of abiotic stimulus; response to heat; associative learning; mechanosensory behavior; long-term memory; aggressive behavior; acute inflammatory response; inflammatory response; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; elevation of cytosolic calcium ion concentration; tachykinin receptor signaling pathway; positive regulat | |
| TACR2 | tachykinin receptor signaling pathway; excretion; muscle contraction | |
| TACR3 | aging; tachykinin receptor signaling pathway; positive regulation of heart rate; response to estradiol stimulus; regulation of dopamine metabolic process; response to cocaine; hyperosmotic salinity response; response to morphine; positive regulation of blood pressure; regulation of feeding behavior; positive regulation of uterine smooth muscle contraction | |
| TACSTD2 | cell surface receptor signaling pathway; visual perception; cell proliferation; negative regulation of epithelial cell migration; response to stimulus; negative regulation of stress fiber assembly; negative regulation of cell motility; negative regulation of ruffle assembly; negative regulation of substrate adhesion-dependent cell spreading; negative regulation of branching involved in ureteric bud morphogenesis | |
| TADA3 | positive regulation of gene expression; regulation of transcription from RNA polymerase II promoter; histone H3 acetylation; intracellular estrogen receptor signaling pathway; positive regulation of transcription, DNA-dependent | |
| TAF10 | transcription from RNA polymerase II promoter; protein homooligomerization; histone H3 acetylation; histone deubiquitination; viral reproduction; gene expression; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription initiation, DNA-dependent | |
| TAF11 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; viral reproduction; positive regulation by host of viral transcription | |
| TAF12 | gene expression; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; transcription initiation, DNA-dependent; viral reproduction; histone H3 acetylation; positive regulation of sequence-specific DNA binding transcription factor activity | |
| TAF13 | transcription from RNA polymerase II promoter; transcription initiation, DNA-dependent; regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; viral reproduction | |
| TAF15 | positive regulation of transcription, DNA-dependent | |
| TAF1A | transcription initiation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; regulation of transcription, DNA-dependent; transcription elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase II promoter; gene expression | |
| TAF1L | male meiosis; cell cycle; histone acetylation; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription initiation, DNA-dependent | |
| TAF2 | positive regulation of transcription from RNA polymerase II promoter; response to organic cyclic compound; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; G2/M transition of mitotic cell cycle | |
| TAF3 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; maintenance of protein location in nucleus; negative regulation of sequence-specific DNA binding transcription factor activity | |
| TAF4 | positive regulation of transcription, DNA-dependent; interspecies interaction between organisms; viral reproduction; gene expression; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; ovarian follicle development; regulation of transcription from RNA polymerase II promoter; transcription initiation, DNA-dependent | |
| TAF4B | regulation of transcription, DNA-dependent; transcription initiation, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; viral reproduction | |
| TAF5 | gene expression; viral reproduction; transcription initiation, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; chromatin modification; histone acetylation; interspecies interaction between organisms | |
| TAF6 | transcription initiation, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; regulation of sequence-specific DNA binding transcription factor activity; negative regulation of cell cycle; viral reproduction; gene expression; negative regulation of cell proliferation | |
| TAF6L | regulation of transcription from RNA polymerase II promoter; transcription initiation, DNA-dependent; chromatin remodeling; regulation of sequence-specific DNA binding transcription factor activity; histone H3 acetylation | |
| TAF7 | negative regulation of histone acetylation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; intracellular estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; spermine transport; transcription initiation, DNA-dependent; transcription from RNA polymerase II promoter; negative regulation of protein kinase activity; transcription initiation from RNA polymerase II promoter | |
| TAF7L | transcription initiation from RNA polymerase II promoter; multicellular organismal development; spermatogenesis; cell differentiation; regulation of transcription, DNA-dependent | |
| TAF8 | positive regulation of transcription, DNA-dependent; maintenance of protein location in nucleus; regulation of fat cell differentiation; inner cell mass cell proliferation; multicellular organismal development; cell differentiation | |
| TAF9 | response to interleukin-1; positive regulation of response to cytokine stimulus; positive regulation of transcription from RNA polymerase II promoter; histone H3 acetylation; negative regulation of apoptotic process; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cell growth; viral reproduction; gene expression; response to DNA damage stimulus; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| TAGLN3 | central nervous system development; muscle organ development | |
| TAL2 | behavior; multicellular organism growth; midbrain development; thalamus development; post-embryonic development; regulation of transcription, DNA-dependent | |
| TALDO1 | pentose-phosphate shunt; energy reserve metabolic process; pentose-phosphate shunt, non-oxidative branch; fructose 6-phosphate metabolic process; glyceraldehyde-3-phosphate metabolic process; small molecule metabolic process; xylulose biosynthetic process; carbohydrate metabolic process | |
| TAMM41 | protein import into mitochondrial matrix; protein transport | |
| TANC1 | - | |
| TANGO2 | - | |
| TAOK3 | G2/M transition DNA damage checkpoint; protein autophosphorylation; MAPK cascade; positive regulation of JNK cascade; negative regulation of JNK cascade; positive regulation of stress-activated MAPK cascade; DNA repair; protein phosphorylation; response to DNA damage stimulus | |
| TARBP1 | regulation of transcription from RNA polymerase II promoter; RNA processing | |
| TARBP2 | negative regulation of protein kinase activity; targeting of mRNA for destruction involved in RNA interference; regulation of translation; production of siRNA involved in RNA interference; gene silencing by RNA; pre-miRNA processing; miRNA loading onto RISC involved in gene silencing by miRNA; negative regulation of defense response to virus by host; regulation of viral transcription; positive regulation of viral genome replication; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter | |
| TARS | translation; tRNA aminoacylation for protein translation; threonyl-tRNA aminoacylation; gene expression | |
| TARS2 | mitochondrial threonyl-tRNA aminoacylation; gene expression; tRNA aminoacylation for protein translation; threonyl-tRNA aminoacylation | |
| TARSL2 | threonyl-tRNA aminoacylation | |
| TAS1R1 | response to stimulus; sensory perception of umami taste; detection of chemical stimulus involved in sensory perception of taste | |
| TAS1R2 | G-protein coupled receptor signaling pathway; detection of chemical stimulus involved in sensory perception of sweet taste; response to stimulus; sensory perception of sweet taste | |
| TAS2R10 | response to stimulus; detection of chemical stimulus involved in sensory perception of taste | |
| TAS2R3 | sensory perception of taste; response to stimulus; signal transduction; detection of chemical stimulus involved in sensory perception of taste | |
| TAS2R38 | sensory perception of taste; response to stimulus | |
| TAS2R8 | response to stimulus; detection of chemical stimulus involved in sensory perception of taste | |
| TAS2R9 | detection of chemical stimulus involved in sensory perception of taste; response to stimulus | |
| TAT | cellular nitrogen compound metabolic process; small molecule metabolic process; response to glucocorticoid stimulus; response to mercury ion; 2-oxoglutarate metabolic process; glutamate metabolic process; L-phenylalanine catabolic process; tyrosine catabolic process; response to oxidative stress; biosynthetic process; response to organic cyclic compound | |
| TATDN1 | - | |
| TATDN2 | endoplasmic reticulum unfolded protein response; activation of signaling protein activity involved in unfolded protein response | |
| TATDN3 | - | |
| TAX1BP1 | apoptotic process; innate immune response; anti-apoptosis; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production | |
| TBATA | - | |
| TBC1D1 | regulation of protein localization | |
| TBC1D10A | - | |
| TBC1D10C | - | |
| TBC1D12 | - | |
| TBC1D13 | - | |
| TBC1D14 | - | |
| TBC1D16 | - | |
| TBC1D17 | - | |
| TBC1D2 | positive regulation of Rab GTPase activity | |
| TBC1D21 | - | |
| TBC1D22A | - | |
| TBC1D23 | - | |
| TBC1D25 | - | |
| TBC1D31 | - | |
| TBC1D32 | - | |
| TBC1D4 | - | |
| TBC1D5 | - | |
| TBC1D8B | - | |
| TBC1D9B | - | |
| TBCC | protein folding; 'de novo' posttranslational protein folding; cellular protein metabolic process; post-chaperonin tubulin folding pathway; GTP catabolic process | |
| TBCCD1 | maintenance of Golgi location; maintenance of centrosome location; regulation of cell migration; regulation of cell shape; cell morphogenesis | |
| TBCE | protein folding; microtubule cytoskeleton organization; post-chaperonin tubulin folding pathway; adult locomotory behavior; post-embryonic development; muscle atrophy; cellular protein metabolic process; developmental growth; peripheral nervous system neuron axonogenesis; 'de novo' posttranslational protein folding | |
| TBCEL | - | |
| TBCK | protein phosphorylation | |
| TBK1 | negative regulation of gene expression; positive regulation of interferon-alpha production; negative regulation of type I interferon production; TRIF-dependent toll-like receptor signaling pathway; positive regulation of interferon-beta production; response to virus; Toll signaling pathway; type I interferon production; I-kappaB kinase/NF-kappaB cascade; activation of innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 4 signaling pathway; defense response to Gram-positive bacterium; MyD88-independent toll-like receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; protein phosphorylation; inflammatory response; innate immune response; interspecies interaction between organisms; toll-like receptor 3 signaling pathway; positive regulation of interferon-beta biosynthetic process | |
| TBL3 | rRNA processing; G-protein signaling, coupled to cGMP nucleotide second messenger | |
| TBP | gene expression; interspecies interaction between organisms; viral reproduction; cell death; spermatogenesis; transcription from RNA polymerase III promoter; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| TBRG4 | G1 phase of mitotic cell cycle; cell cycle arrest; positive regulation of cell proliferation; cellular respiration | |
| TBX10 | anatomical structure morphogenesis; regulation of transcription from RNA polymerase II promoter | |
| TBX15 | embryonic cranial skeleton morphogenesis | |
| TBX18 | negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; negative regulation of transcription from RNA polymerase II promoter | |
| TBX19 | regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; anatomical structure morphogenesis; pituitary gland development; cell fate commitment; positive regulation of transcription from RNA polymerase II promoter | |
| TBX2 | developmental growth involved in morphogenesis; negative regulation of transcription from RNA polymerase II promoter; heart morphogenesis; multicellular organismal development; mammary placode formation; muscle cell fate determination; cell aging; positive regulation of cell proliferation; negative regulation of transcription, DNA-dependent; cardiac muscle tissue development; palate development | |
| TBX20 | patterning of blood vessels; negative regulation of transcription from RNA polymerase II promoter; endoderm formation; neuron migration; muscle contraction; positive regulation of transcription from RNA polymerase II promoter; negative regulation of SMAD protein complex assembly; visceral motor neuron differentiation; dorsal/ventral pattern formation; cell proliferation; blood circulation; embryonic heart tube development; cardiac septum development; endocardial cushion formation; cardiac right ventricle morphogenesis; cardiac chamber formation; foramen ovale closure; negative regulation of transcription, DNA-dependent; pulmonary valve formation; lateral mesoderm formation; aortic valve morphogenesis; tricuspid valve development; cardiac muscle tissue morphogenesis; atrial septum morphogenesis; pulmonary vein morphogenesis; outflow tract septum morphogenesis; heart looping | |
| TBX21 | positive regulation of transcription, DNA-dependent; multicellular organismal development; lymphocyte migration; regulation of immune response; positive regulation of isotype switching to IgG isotypes; response to virus; regulation of transcription, DNA-dependent | |
| TBX22 | negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; multicellular organismal development; regulation of transcription, DNA-dependent | |
| TBX3 | in utero embryonic development; female genitalia development; negative regulation of epithelial cell differentiation; male genitalia development; limbic system development; stem cell maintenance; specification of organ position; organ morphogenesis; anterior/posterior axis specification, embryo; positive regulation of cell proliferation; cell aging; multicellular organismal development; anti-apoptosis; regulation of transcription from RNA polymerase II promoter; atrioventricular bundle cell differentiation; outflow tract morphogenesis; heart looping; follicle-stimulating hormone secretion; cardiac muscle cell fate commitment; positive regulation of stem cell proliferation; sinoatrial node cell development; mammary placode formation; branching involved in mammary gland duct morphogenesis; ventricular septum morphogenesis; palate development; mesoderm morphogenesis; mammary gland development; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regul | |
| TBX4 | skeletal system morphogenesis; limb morphogenesis; angiogenesis; morphogenesis of an epithelium; regulation of transcription, DNA-dependent; multicellular organismal development; embryonic limb morphogenesis; lung development | |
| TBX6 | cell fate specification; signal transduction involved in regulation of gene expression; anatomical structure morphogenesis; mesoderm development; multicellular organismal development; mesoderm formation | |
| TBXA2R | G-protein coupled receptor signaling pathway; blood coagulation; platelet activation | |
| TBXAS1 | small molecule metabolic process; xenobiotic metabolic process; prostanoid metabolic process; fatty acid biosynthetic process; prostaglandin biosynthetic process; icosanoid metabolic process | |
| TCAIM | - | |
| TCEA2 | regulation of transcription from RNA polymerase II promoter; regulation of transcription elongation, DNA-dependent; transcription, DNA-dependent; transcription elongation, DNA-dependent | |
| TCEAL1 | regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter | |
| TCEAL8 | regulation of transcription, DNA-dependent | |
| TCEB2 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; protein complex assembly; positive regulation of viral transcription; viral reproduction; gene expression | |
| TCEB3 | positive regulation of viral transcription; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; viral reproduction | |
| TCERG1 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| TCF12 | cell differentiation; muscle organ development; nervous system development; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; immune response; multicellular organismal development | |
| TCF20 | regulation of transcription, DNA-dependent | |
| TCF23 | multicellular organismal development; muscle organ development; cell differentiation | |
| TCF25 | heart development; negative regulation of transcription from RNA polymerase II promoter | |
| TCF3 | B cell lineage commitment; G1 phase of mitotic cell cycle; natural killer cell differentiation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of muscle cell differentiation; positive regulation of sequence-specific DNA binding transcription factor activity; protein stabilization; Peyer's patch development; cell development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of cell cycle; positive regulation of neuron differentiation; histone H4 acetylation; muscle cell differentiation; response to drug; immunoglobulin V(D)J recombination; T cell differentiation in thymus; response to lipopolysaccharide; positive regulation of B cell proliferation; B cell differentiation; nervous system development; histone H3 acetylation | |
| TCF4 | transcription initiation, DNA-dependent; protein-DNA complex assembly; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of neuron differentiation; cell differentiation; nervous system development; transcription initiation from RNA polymerase II promoter | |
| TCF7L1 | regulation of transcription from RNA polymerase II promoter; axial mesoderm morphogenesis; generation of neurons; stem cell differentiation; canonical Wnt receptor signaling pathway; regulation of stem cell maintenance; positive regulation of transcription from RNA polymerase II promoter during mitosis; chromatin organization; regulation of transcription, DNA-dependent; brain development; anterior/posterior axis specification, embryo; Wnt receptor signaling pathway; neurogenesis; regulation of Wnt receptor signaling pathway; somatic stem cell maintenance; skin development; negative regulation of transcription, DNA-dependent | |
| TCF7L2 | neurogenesis; Wnt receptor signaling pathway; positive regulation of heparan sulfate proteoglycan biosynthetic process; response to glucose stimulus; canonical Wnt receptor signaling pathway; cell proliferation; brain development; cell cycle arrest; anti-apoptosis; regulation of transcription from RNA polymerase II promoter; blood vessel development; negative regulation of transcription from RNA polymerase II promoter; myoblast cell fate commitment; glucose homeostasis; negative regulation of sequence-specific DNA binding transcription factor activity; maintenance of DNA repeat elements; canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition; fat cell differentiation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein export from nucleus; regulation of smooth muscle cell proliferation; generation of neurons; positive regulation of protein kinase B sig | |
| TCFL5 | regulation of cell differentiation; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; multicellular organismal development; spermatogenesis; regulation of cell proliferation | |
| TCHH | keratinization | |
| TCHHL1 | - | |
| TCN1 | cobalamin transport; cobalamin metabolic process; cobalt ion transport; ion transport | |
| TCN2 | cobalamin transport; cobalamin metabolic process; cobalt ion transport; ion transport | |
| TCOF1 | transport; skeletal system development | |
| TCP10L | - | |
| TCP11 | multicellular organismal development; spermatogenesis; cell differentiation | |
| TCTE1 | - | |
| TCTE3 | transport | |
| TCTN1 | multicellular organismal development; cell projection organization; cilium morphogenesis | |
| TCTN2 | cilium morphogenesis; cilium assembly; smoothened signaling pathway; cell projection organization | |
| TDO2 | small molecule metabolic process; tryptophan catabolic process; tryptophan catabolic process to kynurenine; tryptophan catabolic process to acetyl-CoA; cellular nitrogen compound metabolic process | |
| TDP1 | single strand break repair; cell death; double-strand break repair; DNA repair | |
| TDRD1 | piRNA metabolic process; germ cell development; DNA methylation involved in gamete generation; meiosis; multicellular organismal development; gene silencing by RNA; cell differentiation; spermatogenesis | |
| TDRD10 | - | |
| TDRD3 | chromatin modification | |
| TDRD5 | spermatogenesis; spermatid development; cell differentiation; P granule organization; multicellular organismal development; DNA methylation involved in gamete generation | |
| TDRD6 | germ cell development; spermatogenesis; multicellular organismal development; cell differentiation | |
| TDRKH | - | |
| TEAD4 | regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; muscle organ development; embryo implantation; hippo signaling cascade; positive regulation of transcription from RNA polymerase II promoter; skeletal system development; in utero embryonic development; trophectodermal cell fate commitment; cell fate specification; blastocyst formation | |
| TECPR2 | - | |
| TECR | long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; fatty acid elongation; small molecule metabolic process; cellular lipid metabolic process; very long-chain fatty acid biosynthetic process | |
| TECTA | sensory perception of sound; cell-matrix adhesion | |
| TECTB | - | |
| TEDDM1 | - | |
| TEK | positive regulation of actin cytoskeleton reorganization; cell-cell signaling; regulation of establishment or maintenance of cell polarity; peptidyl-tyrosine phosphorylation; negative regulation of angiogenesis; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of intracellular protein kinase cascade; positive regulation of endothelial cell migration; blood coagulation; heart development; negative regulation of endothelial cell apoptosis; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; protein phosphorylation; sprouting angiogenesis; positive regulation of endothelial cell proliferation; endothelial cell proliferation; positive regulation of protein phosphorylation; angiogenesis; negative regulation of apoptotic process; regulation of endothelial cell apoptosis; positive regulation of ERK1 and ERK2 cascade; heart trabecula formation; definitive hemopoiesis; positive regulation of protein kinase B signaling cascade; positive regulation of f | |
| TEKT1 | microtubule cytoskeleton organization | |
| TEKT3 | microtubule cytoskeleton organization | |
| TEKT5 | microtubule cytoskeleton organization | |
| TELO2 | - | |
| TENM1 | - | |
| TEP1 | telomere maintenance via recombination | |
| TEPP | - | |
| TES | negative regulation of cell proliferation | |
| TET1 | regulation of transcription, DNA-dependent; negative regulation of methylation-dependent chromatin silencing; DNA demethylation; stem cell maintenance; inner cell mass cell differentiation; chromatin modification | |
| TET2 | cell cycle; myeloid cell differentiation | |
| TEX10 | - | |
| TEX101 | - | |
| TEX14 | - | |
| TEX15 | fertilization; regulation of protein localization; synaptonemal complex assembly; protein localization to chromosome; homeostasis of number of cells within a tissue; male meiosis; male genitalia development; regulation of double-strand break repair via homologous recombination; spermatogenesis | |
| TEX261 | positive regulation of apoptotic process | |
| TEX35 | - | |
| TEX9 | - | |
| TF | transmembrane transport; transferrin transport; platelet activation; blood coagulation; cellular iron ion homeostasis; iron ion transport; ion transport; platelet degranulation | |
| TFAP2A | negative regulation of transcription from RNA polymerase II promoter; trigeminal nerve development; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; regulation of cell differentiation; positive regulation of neuron apoptosis; negative regulation of apoptotic process; inner ear morphogenesis; embryonic forelimb morphogenesis; positive regulation of bone mineralization; oculomotor nerve formation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription by competitive promoter binding; retina layer formation; positive regulation of gene expression; negative regulation of cell proliferation; sensory perception of sound; transcription from RNA polymerase II promoter; optic cup structural organization; optic vesicle morphogenesis; kidney development; embryonic cranial skeleton morphogenesis; palate development; bone morphogenesis; eyelid development in camera-type eye; positive regulation of tooth mineralizat | |
| TFAP2B | renal water homeostasis; forelimb morphogenesis; negative regulation of transcription from RNA polymerase II promoter; kidney development; regulation of BMP signaling pathway; glucose metabolic process; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; nervous system development; sensory organ development; positive regulation of cell proliferation; negative regulation of cell proliferation; retina layer formation; magnesium ion homeostasis; hindlimb morphogenesis; positive regulation of urine volume; collecting duct development; metanephric nephron development; ductus arteriosus closure; distal tubule development; sodium ion homeostasis; potassium ion homeostasis; calcium ion homeostasis; phosphate ion homeostasis; regulation of insulin secretion; sympathetic nervous system development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; glucose h | |
| TFAP2C | negative regulation of transcription from RNA polymerase II promoter; trophectodermal cell differentiation; hair follicle development; keratinocyte development; somatic stem cell maintenance; regulation of transcription from RNA polymerase II promoter; cell-cell signaling; male gonad development; forebrain neuron fate commitment; cerebral cortex development; germ-line stem cell maintenance; skin development; regulation of epidermis development; positive regulation of transcription from RNA polymerase II promoter; sebaceous gland development; dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis; epithelial cell proliferation involved in mammary gland duct elongation | |
| TFAP2D | positive regulation of transcription, DNA-dependent | |
| TFAP2E | positive regulation of transcription from RNA polymerase II promoter | |
| TFAP4 | regulation of S phase of mitotic cell cycle; protein complex assembly; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; negative regulation of cell proliferation; positive regulation of apoptotic process; negative regulation of apoptotic process; cellular response to dexamethasone stimulus; negative regulation of cell cycle arrest; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cyclin-dependent protein kinase activity; positive regulation by host of viral transcription; negative regulation by host of viral transcription; negative regulation of DNA binding | |
| TFB1M | regulation of transcription, DNA-dependent | |
| TFB2M | transcription from mitochondrial promoter; transcription initiation from mitochondrial promoter; gene expression; positive regulation of transcription, DNA-dependent | |
| TFCP2 | regulation of transcription from RNA polymerase II promoter | |
| TFDP1 | cell proliferation; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; mitotic cell cycle; regulation of transcription from RNA polymerase II promoter | |
| TFDP2 | heart development; G1 phase of mitotic cell cycle; regulation of transcription, DNA-dependent; mitotic cell cycle | |
| TFE3 | regulation of transcription, DNA-dependent; humoral immune response; regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter | |
| TFEB | embryonic placenta development; regulation of transcription, DNA-dependent; humoral immune response; positive regulation of transcription from RNA polymerase II promoter | |
| TFEC | regulation of transcription, DNA-dependent; cellular response to heat | |
| TFIP11 | regulation of transcription, DNA-dependent; biomineral tissue development; RNA splicing; RNA processing; nuclear mRNA splicing, via spliceosome | |
| TFPI | blood coagulation, extrinsic pathway; blood coagulation; negative regulation of endopeptidase activity | |
| TFPT | induction of apoptosis; apoptotic process; regulation of transcription, DNA-dependent; DNA repair; DNA recombination | |
| TFR2 | cellular iron ion homeostasis; proteolysis; iron ion transport | |
| TG | transcytosis; hormone biosynthetic process; response to lipopolysaccharide; regulation of myelination; thyroid gland development; iodide transport; response to pH; synapse assembly; signal transduction; thyroid hormone generation | |
| TGFB1 | positive regulation of transcription from RNA polymerase II promoter; negative regulation of mitotic cell cycle; digestive tract development; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of cell cycle; negative regulation of myoblast differentiation; negative regulation of fat cell differentiation; cell-cell junction organization; regulatory T cell differentiation; ossification involved in bone remodeling; positive regulation of phosphatidylinositol 3-kinase activity; negative regulation of blood vessel endothelial cell migration; positive regulation of blood vessel endothelial cell migration; protein kinase B signaling cascade; positive regulation of MAP kinase activity; T cell homeostasis; myeloid dendritic cell differentiation; myelination; lens fiber cell differentiation; positive regulation of protein kinase B signaling cascade; face morphogenesis; frontal suture morphogenesis; pathway-restricted SMAD protein phosphorylation | |
| TGFBR1 | heart development; lung development; positive regulation of cell growth; collagen fibril organization; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; response to organic cyclic compound; positive regulation of pathway-restricted SMAD protein phosphorylation; pathway-restricted SMAD protein phosphorylation; anterior/posterior pattern specification; post-embryonic development; embryo development; response to toxin; germ cell migration; positive regulation of cell proliferation; aging; embryo implantation; digestive tract development; response to cholesterol; positive regulation of SMAD protein import into nucleus; pharyngeal system development; palate development; parathyroid gland development; positive regulation of protein kinase B signaling cascade; response to electrical stimulus; positive regulation of filopodium assembly; positive regulation of cellular component movement; cell motility; artery morphogenesis; mesenchymal cell differentiation; skeletal system morphogenesis; embryonic | |
| TGFBR2 | embryonic cranial skeleton morphogenesis; positive regulation of NK T cell differentiation; apoptotic process; palate development; myeloid dendritic cell differentiation; response to drug; regulation of cell proliferation; regulation of growth; embryonic hemopoiesis; activation of protein kinase activity; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; positive regulation of cell proliferation; heart development; brain development; transforming growth factor beta receptor signaling pathway; blood vessel development; patterning of blood vessels; vasculogenesis; positive regulation of mesenchymal cell proliferation; positive regulation of tolerance induction to self antigen; positive regulation of B cell tolerance induction; positive regulation of T cell tolerance induction; protein phosphorylation; response to cholesterol; positive regulation of reactive oxygen species metabolic process; pathway-restricted SMAD protein phosphorylation | |
| TGFBR3 | liver development; pathway-restricted SMAD protein phosphorylation; heart trabecula formation; definitive erythrocyte differentiation; cardiac epithelial to mesenchymal transition; definitive hemopoiesis; cardiac muscle cell proliferation; palate development; ventricular cardiac muscle tissue morphogenesis; negative regulation of cellular component movement; negative regulation of epithelial cell proliferation; response to luteinizing hormone stimulus; response to prostaglandin E stimulus; response to follicle-stimulating hormone stimulus; BMP signaling pathway; cell migration; cell growth; intracellular protein kinase cascade; transforming growth factor beta receptor signaling pathway; immune response; heart morphogenesis; epithelial to mesenchymal transition | |
| TGIF1 | positive regulation of neuron differentiation; cellular response to growth factor stimulus; retina development in camera-type eye; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; multicellular organismal development; determination of left/right symmetry; negative regulation of cell proliferation; negative regulation of retinoic acid receptor signaling pathway; positive regulation of fibroblast proliferation; dorsal/ventral pattern formation; negative regulation of gene expression; response to drug | |
| TGM1 | keratinocyte differentiation; protein modification process; peptide cross-linking; keratinization; cell envelope organization | |
| TGM2 | apoptotic cell clearance; salivary gland cavitation; branching involved in salivary gland morphogenesis; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; protein homooligomerization; positive regulation of cell adhesion; positive regulation of inflammatory response; positive regulation of smooth muscle cell proliferation; blood vessel remodeling; induction of apoptosis; metabolic process; peptide cross-linking; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| TGM3 | protein tetramerization; cell envelope organization; keratinization; hair follicle morphogenesis; keratinocyte differentiation; peptide cross-linking; GTP catabolic process; protein modification process | |
| TGM4 | peptide cross-linking; protein polyamination | |
| TGM5 | peptide cross-linking; epidermis development; protein modification process | |
| TGM6 | peptide cross-linking; cell death | |
| TGM7 | peptide cross-linking | |
| TGS1 | RNA capping; ribonucleoprotein complex import into nucleus; RNA methylation; gene expression; small molecule metabolic process; cellular lipid metabolic process; ncRNA metabolic process; spliceosomal snRNP assembly; ribonucleoprotein complex biogenesis; RNA metabolic process; regulation of transcription, DNA-dependent | |
| THAP2 | - | |
| THAP4 | - | |
| THAP6 | - | |
| THAP7 | negative regulation of transcription, DNA-dependent | |
| THAP9 | - | |
| THBD | blood coagulation; female pregnancy; embryo development; response to X-ray; negative regulation of platelet activation; negative regulation of blood coagulation; response to lipopolysaccharide; leukocyte migration; response to cAMP; negative regulation of fibrinolysis | |
| THBS1 | positive regulation of macrophage activation; negative regulation of cGMP-mediated signaling; negative regulation of nitric oxide mediated signal transduction; negative regulation of plasma membrane long-chain fatty acid transport; negative regulation of endothelial cell migration; response to magnesium ion; response to progesterone stimulus; negative regulation of interleukin-12 production; positive regulation of transforming growth factor beta1 production; cellular response to heat; negative regulation of fibroblast growth factor receptor signaling pathway; positive regulation of phosphorylation; response to drug; positive regulation of tumor necrosis factor biosynthetic process; platelet activation; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of blood vessel endothelial cell migration; negative regulation of blood vessel endothelial cell migration; engulfment of apoptotic cell; positive regulation o | |
| THBS2 | positive regulation of synapse assembly; negative regulation of angiogenesis; cell adhesion | |
| THBS3 | cell adhesion; growth plate cartilage development; cell-matrix adhesion; ossification involved in bone maturation; bone trabecula formation | |
| THBS4 | positive regulation of endothelial cell proliferation; cell adhesion; nervous system development; negative regulation of angiogenesis; neuron projection morphogenesis; positive regulation of peptidyl-tyrosine phosphorylation; protein homooligomerization; myoblast migration; positive regulation of cell division; endothelial cell-cell adhesion; positive regulation of neutrophil chemotaxis | |
| THEG | chaperone-mediated protein complex assembly; cell differentiation; spermatogenesis; multicellular organismal development | |
| THEM5 | - | |
| THEMIS | negative T cell selection; positive T cell selection; T cell receptor signaling pathway; multicellular organismal development | |
| THEMIS2 | - | |
| THNSL1 | threonine biosynthetic process | |
| THOC2 | mRNA processing; mRNA export from nucleus; RNA splicing; transport; intronless viral mRNA export from host nucleus | |
| THOC6 | mRNA processing; intronless viral mRNA export from host nucleus; RNA splicing; transport; mRNA export from nucleus | |
| THOP1 | proteolysis | |
| THRA | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly; gene expression; negative regulation of transcription, DNA-dependent; negative regulation of transcription initiation, DNA-dependent; hormone-mediated signaling pathway; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter | |
| THRAP3 | positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; transcription initiation from RNA polymerase II promoter; intracellular steroid hormone receptor signaling pathway | |
| THRB | transcription, DNA-dependent; regulation of transcription, DNA-dependent; gene expression | |
| THSD1 | - | |
| THSD4 | elastic fiber assembly | |
| THUMPD1 | - | |
| THUMPD3 | - | |
| TIA1 | regulation of nuclear mRNA splicing, via spliceosome; negative regulation of cytokine biosynthetic process; negative regulation of translation; apoptotic process; induction of apoptosis | |
| TIAM1 | regulation of catalytic activity; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; apoptotic process; positive regulation of axonogenesis; ephrin receptor signaling pathway; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals | |
| TIAM2 | cellular lipid metabolic process; small molecule metabolic process; apoptotic process; nerve growth factor receptor signaling pathway; small GTPase mediated signal transduction; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; regulation of small GTPase mediated signal transduction | |
| TICAM1 | TRIF-dependent toll-like receptor signaling pathway; signal transduction; induction of apoptosis by extracellular signals; Toll signaling pathway; regulation of protein homodimerization activity; I-kappaB kinase/NF-kappaB cascade; positive regulation of chemokine biosynthetic process; innate immune response; positive regulation of interferon-beta biosynthetic process; positive regulation of nitric oxide biosynthetic process; positive regulation of B cell proliferation; inflammatory response; defense response to virus; apoptotic process; positive regulation of NF-kappaB transcription factor activity; MyD88-independent toll-like receptor signaling pathway; toll-like receptor signaling pathway; macrophage activation involved in immune response; MyD88-dependent toll-like receptor signaling pathway; positive regulation of interleukin-6 production; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling | |
| TICRR | - | |
| TIE1 | in utero embryonic development; signal transduction; mesoderm development; negative regulation of angiogenesis; negative regulation of cell migration; response to retinoic acid; plasma membrane fusion | |
| TIGD2 | regulation of transcription, DNA-dependent | |
| TIGD3 | regulation of transcription, DNA-dependent | |
| TIGD4 | regulation of transcription, DNA-dependent | |
| TIGD7 | regulation of transcription, DNA-dependent | |
| TIGIT | negative regulation of interleukin-12 production; positive regulation of interleukin-10 production; negative regulation of T cell activation | |
| TIMD4 | - | |
| TIMELESS | detection of abiotic stimulus; morphogenesis of an epithelium; response to DNA damage stimulus; cell cycle; mitosis; multicellular organismal development; circadian rhythm; response to abiotic stimulus; regulation of S phase; regulation of cell proliferation; negative regulation of transcription, DNA-dependent; cell division | |
| TIMM21 | protein transport | |
| TIMM22 | protein import into mitochondrial inner membrane; protein transport | |
| TIMP2 | regulation of neuron differentiation; regulation of MAPK cascade; regulation of cAMP metabolic process; negative regulation of cell proliferation | |
| TIMP3 | central nervous system development; aging; visual perception; response to mechanical stimulus; response to hormone stimulus; response to organic cyclic compound; tissue regeneration; response to amino acid stimulus; response to estrogen stimulus; response to stimulus; negative regulation of membrane protein ectodomain proteolysis; response to folic acid | |
| TINAG | Malpighian tubule morphogenesis; cell adhesion; immune response; proteolysis | |
| TINAGL1 | proteolysis; immune response; endosome transport | |
| TINF2 | protein localization to chromosome; negative regulation of telomere maintenance via telomerase; positive regulation of telomere maintenance; negative regulation of telomere maintenance; telomere assembly; negative regulation of protein ADP-ribosylation; telomere maintenance via telomere lengthening; telomere maintenance; protein localization to chromosome, telomeric region; negative regulation of epithelial cell proliferation | |
| TIPARP | hemopoiesis; nitrogen compound metabolic process; multicellular organismal metabolic process; protein ADP-ribosylation; post-embryonic development; female gonad development; estrogen metabolic process; androgen metabolic process; vasculogenesis; kidney development; face morphogenesis; palate development; smooth muscle tissue development; skeletal system morphogenesis; platelet-derived growth factor receptor signaling pathway | |
| TIRAP | positive regulation of interleukin-8 production; toll-like receptor 2 signaling pathway; innate immune response; cell surface receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; positive regulation of protein homodimerization activity; positive regulation of neutrophil chemotaxis; negative regulation of growth of symbiont in host; toll-like receptor 1 signaling pathway; positive regulation of tumor necrosis factor production; positive regulation of toll-like receptor 2 signaling pathway; positive regulation of interleukin-15 production; positive regulation of interleukin-12 production; MyD88-dependent toll-like receptor signaling pathway; Toll signaling pathway; cellular response to lipoteichoic acid; cellular response to bacterial lipopeptide; positive regulation of ERK1 and ERK2 cascade; 3'-UTR-mediated mRNA stabilization; positive regulation of toll-like receptor 3 signaling pathway; regulation of interferon-beta production; response to lipopolysaccharide; positive r | |
| TJP1 | blastocyst formation; apoptotic process; cellular component disassembly involved in apoptosis; cell-cell junction assembly | |
| TJP2 | apoptotic process; cellular component disassembly involved in apoptosis | |
| TJP3 | - | |
| TKFC | innate immune response; glycerol metabolic process | |
| TKTL2 | - | |
| TLDC1 | - | |
| TLDC2 | - | |
| TLE4 | negative regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway | |
| TLK1 | intracellular protein transport; intracellular signal transduction; protein phosphorylation; regulation of chromatin assembly or disassembly; response to DNA damage stimulus; cell cycle; chromatin modification | |
| TLL1 | skeletal system development; cell differentiation; proteolysis; multicellular organismal development | |
| TLL2 | proteolysis; multicellular organismal development; cell differentiation | |
| TLN1 | cell-cell junction assembly; endoplasmic reticulum unfolded protein response; cortical actin cytoskeleton organization; platelet activation; blood coagulation; axon guidance; cell adhesion; cell-substrate junction assembly; cytoskeletal anchoring at plasma membrane; activation of signaling protein activity involved in unfolded protein response; muscle contraction; cellular component movement; platelet degranulation | |
| TLN2 | cell adhesion; cell-cell junction assembly; cytoskeletal anchoring at plasma membrane | |
| TLR1 | immune response; toll-like receptor signaling pathway; microglial cell activation involved in immune response; inflammatory response; signal transduction; response to bacterial lipoprotein; macrophage activation; detection of triacyl bacterial lipopeptide; positive regulation of tumor necrosis factor biosynthetic process; defense response to bacterium; innate immune response; positive regulation of interleukin-6 biosynthetic process; pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; cellular response to triacyl bacterial lipopeptide | |
| TLR10 | MyD88-dependent toll-like receptor signaling pathway; inflammatory response; immune response; signal transduction; innate immune response | |
| TLR2 | toll-like receptor 4 signaling pathway; lipopolysaccharide-mediated signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of toll-like receptor signaling pathway; positive regulation of tumor necrosis factor production; positive regulation of interleukin-8 production; positive regulation of interleukin-6 production; positive regulation of interleukin-18 production; positive regulation of interleukin-12 production; positive regulation of interferon-beta production; positive regulation of chemokine production; positive regulation of NF-kappaB import into nucleus; detection of triacyl bacterial lipopeptide; detection of diacyl bacterial lipopeptide; innate immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of inflammatory response; positive regulation of NF-kappaB transcription factor activity; positive regulation of nitric-oxide synthase biosynthetic process; cellular response to bacterial li | |
| TLR4 | response to insulin stimulus; response to ethanol; positive regulation of nitric oxide biosynthetic process; positive regulation of interleukin-8 biosynthetic process; positive regulation of interferon-beta biosynthetic process; positive regulation of MHC class II biosynthetic process; innate immune response; positive regulation of interleukin-12 biosynthetic process; positive regulation of DNA binding; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; defense response to bacterium; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of NF-kappaB import into nucleus; macrophage activation; T-helper 1 type immune response; toll-like receptor 4 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; intestinal epithelial structure maintenance; cellular response to mechanical stimulus; cellular response to lipoteichoic acid; cellular response to lipopolysaccharide; response to fatty aci | |
| TLR5 | MyD88-dependent toll-like receptor signaling pathway; cellular response to mechanical stimulus; innate immune response; positive regulation of toll-like receptor signaling pathway; positive regulation of interleukin-8 production; signal transduction; inflammatory response | |
| TLR6 | signal transduction; toll-like receptor 2 signaling pathway; activation of NF-kappaB-inducing kinase activity; Toll signaling pathway; T-helper 1 type immune response; toll-like receptor 1 signaling pathway; detection of diacyl bacterial lipopeptide; defense response to bacterium; positive regulation of I-kappaB kinase/NF-kappaB cascade; immune response; inflammatory response; MyD88-dependent toll-like receptor signaling pathway; positive regulation of JUN kinase activity; innate immune response; positive regulation of interleukin-6 biosynthetic process; toll-like receptor signaling pathway; cellular response to diacyl bacterial lipopeptide; toll-like receptor 4 signaling pathway | |
| TLR7 | innate immune response; positive regulation of interleukin-8 production; positive regulation of interferon-gamma biosynthetic process; positive regulation of NF-kappaB import into nucleus; positive regulation of interleukin-6 production; response to chemical stimulus; toll-like receptor 7 signaling pathway; positive regulation of interferon-beta biosynthetic process; I-kappaB phosphorylation; defense response to virus; pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; signal transduction; microglial cell activation involved in immune response; positive regulation of chemokine production; positive regulation of inflammatory response; cellular response to mechanical stimulus; positive regulation of interleukin-8 biosynthetic process; positive regulation of interferon-alpha biosynthetic process | |
| TLR8 | positive regulation of interleukin-8 biosynthetic process; I-kappaB kinase/NF-kappaB cascade; inflammatory response; response to virus; signal transduction; positive regulation of interferon-gamma biosynthetic process; defense response to virus; positive regulation of interferon-beta biosynthetic process; cellular response to mechanical stimulus; positive regulation of interferon-alpha biosynthetic process; positive regulation of innate immune response; innate immune response; immunoglobulin mediated immune response | |
| TLR9 | positive regulation of chemokine production; positive regulation of toll-like receptor signaling pathway; positive regulation of interferon-beta production; positive regulation of NF-kappaB import into nucleus; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; positive regulation of interleukin-18 production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; negative regulation of toll-like receptor signaling pathway; positive regulation of tumor necrosis factor production; positive regulation of inflammatory response; negative regulation of interleukin-8 production; positive regulation of interferon-beta biosynthetic process; defense response to bacterium; negative regulation of interleukin-6 production; positive regulation of nitric-oxide synthase biosynthetic process; negative regulation of NF-kappaB transcription factor activity; maintenance of gastrointestinal epithelium; positive regulation of NF-kappaB tra | |
| TLX3 | central nervous system development; multicellular organismal development; regulation of respiratory gaseous exchange by neurological system process; neuron migration; respiratory gaseous exchange; negative regulation of neuron differentiation; neuron fate specification | |
| TM2D2 | - | |
| TM4SF19 | - | |
| TM6SF2 | - | |
| TM7SF3 | - | |
| TM9SF1 | autophagy | |
| TM9SF3 | - | |
| TM9SF4 | - | |
| TMBIM1 | - | |
| TMBIM6 | negative regulation of apoptotic process | |
| TMC1 | sensory perception of sound | |
| TMC2 | - | |
| TMC4 | - | |
| TMC5 | - | |
| TMC7 | - | |
| TMC8 | - | |
| TMCC1 | - | |
| TMCO1 | - | |
| TMCO2 | - | |
| TMCO3 | cation transport; transmembrane transport | |
| TMCO5A | - | |
| TMED3 | protein transport | |
| TMED9 | protein transport; protein exit from endoplasmic reticulum; early endosome to Golgi transport; positive regulation of organelle organization; Golgi organization; COPI coating of Golgi vesicle | |
| TMEFF2 | - | |
| TMEM101 | signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| TMEM104 | - | |
| TMEM11 | mitochondrion organization | |
| TMEM117 | - | |
| TMEM130 | - | |
| TMEM132B | - | |
| TMEM132D | negative regulation of phosphatase activity | |
| TMEM132E | - | |
| TMEM136 | - | |
| TMEM138 | - | |
| TMEM140 | - | |
| TMEM144 | - | |
| TMEM145 | - | |
| TMEM150A | catabolic process | |
| TMEM151A | - | |
| TMEM154 | - | |
| TMEM156 | - | |
| TMEM161B | - | |
| TMEM164 | - | |
| TMEM168 | - | |
| TMEM17 | smoothened signaling pathway; cell projection organization; cilium assembly | |
| TMEM171 | - | |
| TMEM173 | positive regulation of protein binding; activation of innate immune response; positive regulation of defense response to virus by host; apoptotic process; positive regulation of protein import into nucleus, translocation; cellular response to exogenous dsRNA; defense response to virus; positive regulation of transcription from RNA polymerase II promoter; innate immune response; positive regulation of transcription factor import into nucleus; interferon-beta production | |
| TMEM175 | - | |
| TMEM176A | - | |
| TMEM176B | organ morphogenesis; cell differentiation | |
| TMEM177 | - | |
| TMEM178A | - | |
| TMEM181 | pathogenesis | |
| TMEM184C | - | |
| TMEM186 | - | |
| TMEM187 | - | |
| TMEM192 | - | |
| TMEM196 | - | |
| TMEM198 | - | |
| TMEM199 | - | |
| TMEM2 | multicellular organismal development | |
| TMEM200A | - | |
| TMEM201 | - | |
| TMEM202 | - | |
| TMEM205 | - | |
| TMEM207 | - | |
| TMEM214 | - | |
| TMEM217 | - | |
| TMEM219 | - | |
| TMEM225 | negative regulation of phosphatase activity | |
| TMEM242 | - | |
| TMEM245 | - | |
| TMEM25 | - | |
| TMEM252 | - | |
| TMEM255A | - | |
| TMEM255B | - | |
| TMEM26 | - | |
| TMEM266 | - | |
| TMEM30B | positive regulation of protein exit from endoplasmic reticulum | |
| TMEM38A | ion transport; potassium ion transmembrane transport; potassium ion transport | |
| TMEM39A | - | |
| TMEM39B | - | |
| TMEM40 | - | |
| TMEM41A | - | |
| TMEM41B | - | |
| TMEM44 | - | |
| TMEM45A | - | |
| TMEM45B | - | |
| TMEM50B | - | |
| TMEM51 | - | |
| TMEM53 | - | |
| TMEM54 | - | |
| TMEM57 | brain development | |
| TMEM62 | - | |
| TMEM63A | - | |
| TMEM63B | - | |
| TMEM65 | - | |
| TMEM67 | cilium assembly; ER-associated protein catabolic process; branching morphogenesis of a tube; cilium morphogenesis; cell projection organization; negative regulation of centrosome duplication | |
| TMEM70 | mitochondrial proton-transporting ATP synthase complex assembly | |
| TMEM71 | - | |
| TMEM74B | - | |
| TMEM79 | - | |
| TMEM81 | - | |
| TMEM86A | - | |
| TMEM87B | - | |
| TMEM8A | cell adhesion | |
| TMEM8B | cell adhesion; cell-matrix adhesion; regulation of mitotic cell cycle; regulation of growth | |
| TMEM91 | response to biotic stimulus | |
| TMEM94 | - | |
| TMEM95 | - | |
| TMEM98 | - | |
| TMF1 | regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| TMIE | sensory perception of sound; inner ear morphogenesis | |
| TMIGD1 | - | |
| TMLHE | small molecule metabolic process; cellular nitrogen compound metabolic process; carnitine biosynthetic process; negative regulation of oxidoreductase activity | |
| TMOD2 | neuron-neuron synaptic transmission; learning or memory; positive regulation of G-protein coupled receptor protein signaling pathway; nervous system development | |
| TMPO | regulation of transcription, DNA-dependent | |
| TMPRSS11B | proteolysis | |
| TMPRSS11D | proteolysis; respiratory gaseous exchange; regulation of growth | |
| TMPRSS11F | proteolysis | |
| TMPRSS13 | proteolysis | |
| TMPRSS15 | proteolysis | |
| TMPRSS2 | proteolysis | |
| TMPRSS3 | cellular sodium ion homeostasis; proteolysis; sensory perception of sound | |
| TMPRSS4 | proteolysis | |
| TMPRSS9 | proteolysis | |
| TMTC1 | - | |
| TMTC2 | - | |
| TMUB1 | - | |
| TMX2 | cell redox homeostasis | |
| TMX3 | glycerol ether metabolic process; cell redox homeostasis | |
| TNC | prostate gland epithelium morphogenesis; mesenchymal-epithelial cell signaling involved in prostate gland development; peripheral nervous system axon regeneration; positive regulation of gene expression; response to wounding; positive regulation of cell proliferation; neuromuscular junction development; signal transduction; cell adhesion | |
| TNFAIP2 | angiogenesis; cell differentiation; multicellular organismal development | |
| TNFAIP3 | negative regulation of interleukin-6 production; B-1 B cell homeostasis; response to molecule of bacterial origin; regulation of germinal center formation; proteolysis; anti-apoptosis; protein deubiquitination; negative regulation of protein ubiquitination; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production; response to muramyl dipeptide; negative regulation of interleukin-1 beta production; negative regulation of interleukin-2 production; regulation of defense response to virus by host; cellular response to lipopolysaccharide; tolerance induction to lipopolysaccharide; negative regulation of osteoclast proliferation; protein K48-linked ubiquitination; protein K63-linked deubiquitination; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway; negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway; nucleotide-binding oligomerization domain containing signaling path | |
| TNFAIP6 | cell-cell signaling; inflammatory response; cell adhesion; signal transduction | |
| TNFAIP8L2 | innate immune response | |
| TNFAIP8L3 | - | |
| TNFRSF11A | ossification; response to lipopolysaccharide; adaptive immune response; monocyte chemotaxis; signal transduction; cell-cell signaling; positive regulation of cell proliferation; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling; TNFSF11-mediated signaling pathway; positive regulation of fever generation by positive regulation of prostaglandin secretion; response to interleukin-1; mammary gland alveolus development; circadian temperature homeostasis; positive regulation of NF-kappaB transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of JUN kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; response to tumor necrosis factor; response to cytokine stimulus; tumor necrosis factor-mediated signaling pathway; lymph node development; osteoclast differentiation; multicellular organismal development | |
| TNFRSF11B | apoptotic process; signal transduction; response to nutrient; extracellular matrix organization; response to magnesium ion; negative regulation of odontogenesis of dentin-containing tooth; response to drug; response to estrogen stimulus; negative regulation of bone resorption; response to arsenic-containing substance; skeletal system development | |
| TNFRSF13B | negative regulation of B cell proliferation; cell surface receptor signaling pathway; B cell homeostasis | |
| TNFRSF17 | multicellular organismal development; signal transduction; cell proliferation; tumor necrosis factor-mediated signaling pathway | |
| TNFRSF19 | apoptotic process; tumor necrosis factor-mediated signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; induction of apoptosis; hair follicle development; JNK cascade | |
| TNFRSF21 | neuron apoptosis; small molecule metabolic process; cellular lipid metabolic process; signal transduction | |
| TNFRSF25 | apoptotic process; induction of apoptosis; signal transduction; cell surface receptor signaling pathway; induction of apoptosis by extracellular signals; tumor necrosis factor-mediated signaling pathway; regulation of apoptotic process | |
| TNFRSF4 | negative regulation of T cell apoptosis; inflammatory response; positive regulation of immunoglobulin secretion; negative regulation of cytokine secretion; negative regulation of transcription, DNA-dependent; regulation of protein kinase activity; positive regulation of anti-apoptosis; negative regulation of sequence-specific DNA binding transcription factor activity; regulation of apoptotic process; T cell proliferation; tumor necrosis factor-mediated signaling pathway; positive regulation of B cell proliferation; cellular defense response; immune response | |
| TNFRSF6B | anti-apoptosis; apoptotic process | |
| TNFRSF8 | cellular response to mechanical stimulus; signal transduction; positive regulation of TRAIL biosynthetic process; tumor necrosis factor-mediated signaling pathway; negative regulation of cell proliferation; positive regulation of apoptotic process; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of NF-kappaB transcription factor activity | |
| TNFSF10 | positive regulation of extrinsic apoptotic signaling pathway; positive regulation of release of cytochrome c from mitochondria; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; activation of pro-apoptotic gene products; induction of apoptosis by extracellular signals; cell-cell signaling; signal transduction; immune response; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; apoptotic process | |
| TNFSF11 | positive regulation of I-kappaB kinase/NF-kappaB cascade; tumor necrosis factor-mediated signaling pathway; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling; TNFSF11-mediated signaling pathway; positive regulation of fever generation by positive regulation of prostaglandin secretion; ERK1 and ERK2 cascade; mammary gland alveolus development; positive regulation of protein kinase B signaling cascade; positive regulation of corticotropin-releasing hormone secretion; protein homooligomerization; positive regulation of NF-kappaB transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of T cell activation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of MAP kinase activity; positive regulation of homotypic cell-cell adhesion; mammary gland epithelial cell proliferation; positive regulation of phosphorylation; positive regulation of bone resorption; positive regulati | |
| TNFSF8 | induction of apoptosis; immune response; signal transduction; cell-cell signaling; cell proliferation | |
| TNIP1 | translation; negative regulation of viral genome replication; glycoprotein biosynthetic process; defense response | |
| TNIP3 | - | |
| TNK2 | endocytosis; regulation of clathrin-mediated endocytosis; positive regulation of peptidyl-tyrosine phosphorylation; protein ubiquitination; phosphorylation; small GTPase mediated signal transduction; cell surface receptor signaling pathway | |
| TNKS | regulation of telomere maintenance via telomerase; positive regulation of canonical Wnt receptor signaling pathway; protein auto-ADP-ribosylation; protein poly-ADP-ribosylation; protein localization to chromosome, telomeric region; spindle assembly; mRNA transport; negative regulation of DNA binding; positive regulation of telomere maintenance via telomerase; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; protein transport; mitotic spindle organization; protein ADP-ribosylation; protein polyubiquitination | |
| TNKS1BP1 | mRNA metabolic process; RNA metabolic process; gene expression; telomere maintenance via telomerase; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | |
| TNMD | endothelial cell morphogenesis; negative regulation of endothelial cell proliferation; negative regulation of angiogenesis | |
| TNN | cell-matrix adhesion; cell migration; signal transduction; cell growth; axonogenesis | |
| TNNT1 | skeletal muscle contraction; muscle filament sliding; slow-twitch skeletal muscle fiber contraction; negative regulation of muscle contraction | |
| TNNT2 | ATP catabolic process; regulation of heart contraction; muscle filament sliding; negative regulation of ATPase activity; positive regulation of ATPase activity; response to calcium ion; ventricular cardiac muscle tissue morphogenesis | |
| TNPO1 | mRNA metabolic process; interspecies interaction between organisms; RNA metabolic process; gene expression; protein import into nucleus, translocation | |
| TNPO3 | splicing factor protein import into nucleus; protein transport | |
| TNR | negative regulation of cell-cell adhesion; signal transduction; negative regulation of synaptic transmission; negative regulation of axon extension involved in regeneration; locomotory exploration behavior; extracellular matrix organization; telencephalon cell migration; negative regulation of neuron projection development; associative learning; axon guidance; neuron cell-cell adhesion; cell adhesion; synapse organization; neuromuscular process controlling balance; long-term synaptic potentiation; positive regulation of transmission of nerve impulse; positive regulation of synaptic transmission, glutamatergic | |
| TNRC6A | gene silencing by RNA; negative regulation of translation involved in gene silencing by miRNA; cellular response to starvation; regulation of translation | |
| TNS1 | fibroblast migration; cell-substrate junction assembly | |
| TNS2 | negative regulation of cell proliferation; intracellular signal transduction | |
| TNS3 | intracellular signal transduction; positive regulation of cell proliferation; cell migration; lung alveolus development | |
| TNS4 | apoptotic process; protein localization | |
| TOB1 | negative regulation of cell proliferation | |
| TOB2 | regulation of gene expression; female gamete generation; negative regulation of cell proliferation; negative regulation of osteoclast differentiation; positive regulation of ossification | |
| TOM1 | intracellular protein transport; endocytosis; endosome transport; protein transport | |
| TOM1L1 | intracellular protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; positive regulation of catalytic activity | |
| TOM1L2 | intracellular protein transport | |
| TOMM34 | protein targeting to mitochondrion | |
| TOP1MT | DNA topological change | |
| TOP3A | meiosis; DNA topological change | |
| TOP3B | DNA topological change; chromosome segregation | |
| TOPORS | protein ubiquitination; DNA damage response, signal transduction resulting in induction of apoptosis; regulation of cell proliferation; ubiquitin-dependent protein catabolic process; transcription, DNA-dependent; proteasomal ubiquitin-dependent protein catabolic process; response to DNA damage stimulus; apoptotic process; positive regulation of transcription, DNA-dependent; maintenance of protein location in nucleus; protein sumoylation; protein localization to nucleus | |
| TOR1AIP1 | - | |
| TOR1B | chaperone mediated protein folding requiring cofactor; response to unfolded protein | |
| TOR2A | chaperone mediated protein folding requiring cofactor | |
| TOX | - | |
| TOX2 | regulation of transcription, DNA-dependent | |
| TP53 | protein complex assembly; multicellular organismal development; apoptotic process; response to DNA damage stimulus; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; ER overload response; cell cycle arrest; Ras protein signal transduction; gastrulation; regulation of transcription, DNA-dependent; double-strand break repair; nucleotide-excision repair; base-excision repair; T cell lineage commitment; B cell lineage commitment; T cell proliferation involved in immune response; somitogenesis; in utero embryonic development; response to X-ray; cellular response to drug; multicellular organism growth; cellular response to UV; cellular protein localization; T cell differentiation in thymus; positive regulation of protein oligomerization; mitotic cell cycle G1/S transition DNA damage checkpoint; positive regulation of histone deacetylation; negative regulation | |
| TP53BP1 | positive regulation of transcription, DNA-dependent; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; double-strand break repair; DNA repair; double-strand break repair via homologous recombination | |
| TP53BP2 | apoptotic process; induction of apoptosis; signal transduction; central nervous system development; heart development; embryo development ending in birth or egg hatching; negative regulation of cell cycle; response to ionizing radiation | |
| TP53INP1 | apoptotic process; induction of apoptosis; response to stress; cell cycle arrest | |
| TP53INP2 | - | |
| TP53TG5 | intracellular signal transduction; negative regulation of cell growth | |
| TP63 | ectoderm and mesoderm interaction; hair follicle morphogenesis; polarized epithelial cell differentiation; prostate gland development; embryonic limb morphogenesis; response to gamma radiation; multicellular organismal aging; response to X-ray; proximal/distal pattern formation; organ morphogenesis; cell aging; mitotic cell cycle G1/S transition DNA damage checkpoint; pattern specification process; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; induction of apoptosis; anti-apoptosis; apoptotic process; epithelial cell development; positive regulation of mesenchymal cell proliferation; establishment of planar polarity; skeletal system development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; prostatic bud formation; cloacal septation; urinary bladder development; protein homotetramerization; female genitalia morphogenesis; smooth muscle tissue development; anatomical s | |
| TP73 | positive regulation of cell size; mitotic cell cycle G1/S transition DNA damage checkpoint; cerebrospinal fluid secretion; cellular response to UV; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; positive regulation of apoptotic process; negative regulation of JUN kinase activity; negative regulation of neuron apoptosis; negative regulation of neuron differentiation; activation of MAPK activity; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; digestive tract morphogenesis; neuron development; positive regulation of oligodendrocyte differentiation; protein tetramerization; negative regulation of transcription from RNA polymerase II promoter; hippocampus development; kidney development; release of cytochrome c from mitochondria; mismatch repair; regulation of transcription, DNA-dependent; inflammatory response; response to DNA damage stimulus; DNA damage response, signal transduction by | |
| TPBG | cell adhesion | |
| TPCN2 | transmembrane transport; regulation of calcium ion transport via voltage-gated calcium channel activity; ion transport; cellular calcium ion homeostasis; smooth muscle contraction; release of sequestered calcium ion into cytosol | |
| TPD52L1 | G2/M transition of mitotic cell cycle; DNA fragmentation involved in apoptotic nuclear change; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of MAP kinase activity; positive regulation of JNK cascade | |
| TPD52L3 | - | |
| TPGS1 | spermatogenesis; adult behavior; cell differentiation; sperm axoneme assembly; multicellular organismal development | |
| TPH1 | serotonin biosynthetic process; mammary gland alveolus development; bone remodeling; indolalkylamine biosynthetic process; small molecule metabolic process; response to stress; aromatic amino acid family metabolic process; cellular nitrogen compound metabolic process | |
| TPH2 | aromatic amino acid family metabolic process; circadian rhythm; response to stress; response to activity; response to nutrient levels; cellular nitrogen compound metabolic process; serotonin biosynthetic process; response to estrogen stimulus; small molecule metabolic process; indolalkylamine biosynthetic process; response to glucocorticoid stimulus; response to calcium ion; cellular response to lithium ion | |
| TPI1 | carbohydrate metabolic process; small molecule metabolic process; glyceraldehyde-3-phosphate metabolic process; embryo development; pentose-phosphate shunt; glycolysis; gluconeogenesis; glucose metabolic process | |
| TPK1 | vitamin metabolic process; water-soluble vitamin metabolic process; thiamine metabolic process; thiamine diphosphate biosynthetic process; thiamine-containing compound metabolic process; small molecule metabolic process | |
| TPM1 | cardiac muscle contraction; ventricular cardiac muscle tissue morphogenesis; positive regulation of stress fiber assembly; positive regulation of cell adhesion; sarcomere organization; wound healing; cellular response to reactive oxygen species; positive regulation of ATPase activity; negative regulation of cell migration; muscle filament sliding; regulation of heart contraction; cytoskeleton organization; regulation of muscle contraction; muscle contraction; cellular component movement; positive regulation of heart rate by epinephrine; ruffle organization | |
| TPM2 | muscle contraction; muscle filament sliding; regulation of ATPase activity | |
| TPM4 | cellular component movement; muscle contraction; response to oxidative stress; muscle filament sliding | |
| TPMT | nucleobase-containing compound metabolic process; xenobiotic metabolic process; methylation; small molecule metabolic process | |
| TPP1 | nervous system development; lipid metabolic process; activation of signaling protein activity involved in unfolded protein response; lysosome organization; proteolysis; protein catabolic process; cell death; endoplasmic reticulum unfolded protein response; peptide catabolic process; bone resorption; neuromuscular process controlling balance | |
| TPP2 | protein polyubiquitination; antigen processing and presentation of peptide antigen via MHC class I; proteolysis | |
| TPPP2 | - | |
| TPR | glucose transport; mitotic cell cycle spindle assembly checkpoint; protein import into nucleus; seryl-tRNA aminoacylation; carbohydrate metabolic process; hexose transport; regulation of glucose transport; protein transport; viral reproduction; cytokine-mediated signaling pathway; small molecule metabolic process; mRNA transport; transmembrane transport | |
| TPRN | sensory perception of sound | |
| TPST2 | peptidyl-tyrosine sulfation | |
| TPX2 | apoptotic process; cell cycle; mitosis; cell proliferation; activation of protein kinase activity; cell division; regulation of mitotic spindle organization | |
| TRA2B | nuclear mRNA splicing, via spliceosome; positive regulation of nuclear mRNA splicing, via spliceosome; response to reactive oxygen species; RNA splicing, via transesterification reactions; regulation of alternative nuclear mRNA splicing, via spliceosome | |
| TRABD | - | |
| TRADD | apoptotic process; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; signal transduction; induction of apoptosis by extracellular signals; activation of pro-apoptotic gene products; tumor necrosis factor-mediated signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of hair follicle development; extrinsic apoptotic signaling pathway | |
| TRAF1 | positive regulation of NF-kappaB transcription factor activity; protein complex assembly; signal transduction; regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| TRAF2 | regulation of apoptotic process; activation of pro-apoptotic gene products; activation of cysteine-type endopeptidase activity involved in apoptotic process; signal transduction; activation of NF-kappaB-inducing kinase activity; positive regulation of extrinsic apoptotic signaling pathway; protein K63-linked ubiquitination; protein homotrimerization; protein autoubiquitination; positive regulation of NF-kappaB transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; induction of apoptosis by extracellular signals; positive regulation of T cell activation; innate immune response; cellular protein complex assembly; positive regulation of JUN kinase activity; positive regulation of interleukin-2 production; tumor necrosis factor-mediated signaling pathway; apoptotic process; protein complex assembly; positive regulation of T cell cytokine production | |
| TRAF3 | regulation of defense response to virus; regulation of interferon-beta production; regulation of cytokine production; toll-like receptor signaling pathway; induction of apoptosis; signal transduction; regulation of proteolysis; negative regulation of NF-kappaB transcription factor activity; innate immune response; regulation of apoptotic process; tumor necrosis factor-mediated signaling pathway; negative regulation of type I interferon production | |
| TRAF3IP1 | - | |
| TRAF3IP2 | intracellular signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade | |
| TRAF3IP3 | - | |
| TRAF5 | signal transduction; positive regulation of NF-kappaB transcription factor activity; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; positive regulation of cell proliferation | |
| TRAF7 | regulation of transcription, DNA-dependent; activation of MAPKKK activity; apoptotic process; positive regulation of MAPK cascade; regulation of apoptotic process; protein ubiquitination | |
| TRAFD1 | negative regulation of innate immune response; response to cytokine stimulus | |
| TRAIP | induction of apoptosis; signal transduction; cell proliferation | |
| TRAK1 | endosome to lysosome transport; regulation of transcription from RNA polymerase II promoter; protein O-linked glycosylation; protein targeting | |
| TRAK2 | transport; protein O-linked glycosylation; protein targeting; regulation of transcription from RNA polymerase II promoter | |
| TRAM1L1 | protein transport | |
| TRAPPC10 | sodium ion export; vesicle-mediated transport; sodium ion transport | |
| TRAPPC11 | vesicle-mediated transport | |
| TRAPPC12 | vesicle-mediated transport | |
| TRAPPC3 | vesicle-mediated transport; ER to Golgi vesicle-mediated transport | |
| TRAPPC6A | vesicle-mediated transport | |
| TRAPPC8 | vesicle-mediated transport; ER to Golgi vesicle-mediated transport | |
| TRAPPC9 | cell differentiation | |
| TRAT1 | positive regulation of T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; positive regulation of calcium-mediated signaling; cellular defense response; T cell receptor signaling pathway; negative regulation of receptor recycling; negative regulation of transport | |
| TRDMT1 | tRNA processing; C-5 methylation of cytosine; DNA methylation; response to amphetamine | |
| TREML1 | platelet activation; calcium-mediated signaling; innate immune response | |
| TRERF1 | cholesterol catabolic process; regulation of hormone biosynthetic process; positive regulation of transcription, DNA-dependent; homeostatic process; multicellular organismal development; steroid biosynthetic process | |
| TREX1 | DNA recombination; mismatch repair; DNA repair; DNA replication; cell death; cellular response to interferon-beta | |
| TRHDE | proteolysis; signal transduction; cell-cell signaling | |
| TRHR | G-protein coupled receptor signaling pathway | |
| TRIB1 | negative regulation of smooth muscle cell migration; protein phosphorylation; negative regulation of protein kinase activity; JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of smooth muscle cell proliferation; negative regulation of sequence-specific DNA binding transcription factor activity; regulation of MAP kinase activity; response to lipopolysaccharide | |
| TRIM13 | signal transduction; anatomical structure morphogenesis; ER-associated protein catabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; protein autoubiquitination | |
| TRIM14 | - | |
| TRIM17 | protein autoubiquitination | |
| TRIM2 | neuroprotection; protein ubiquitination | |
| TRIM22 | interspecies interaction between organisms; regulation of transcription, DNA-dependent; immune response; response to virus; protein trimerization | |
| TRIM23 | protein ADP-ribosylation; GTP catabolic process; small GTPase mediated signal transduction; protein ubiquitination; interspecies interaction between organisms; positive regulation of catalytic activity | |
| TRIM24 | regulation of protein stability; transcription from RNA polymerase II promoter; negative regulation of cell proliferation; protein ubiquitination; protein catabolic process; regulation of apoptotic process; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; protein autophosphorylation; calcium ion homeostasis; regulation of vitamin D receptor signaling pathway; cellular response to estrogen stimulus | |
| TRIM28 | protein oligomerization; protein autophosphorylation; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; epithelial to mesenchymal transition; DNA repair; gene expression; protein ubiquitination; positive regulation of DNA repair; protein sumoylation | |
| TRIM29 | transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| TRIM3 | nervous system development; protein transport | |
| TRIM32 | positive regulation of neurogenesis; positive regulation of cell cycle; positive regulation of cell migration; positive regulation of protein catabolic process; response to tumor necrosis factor; positive regulation of neuron differentiation; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of cell motility; positive regulation of NF-kappaB transcription factor activity; fat cell differentiation; negative regulation of fibroblast proliferation; negative regulation of apoptotic process; positive regulation of cell growth; protein ubiquitination; response to UV; protein polyubiquitination; innate immune response; positive regulation of proteolysis | |
| TRIM33 | negative regulation of transcription, DNA-dependent; negative regulation of BMP signaling pathway; regulation of transforming growth factor beta receptor signaling pathway; protein ubiquitination | |
| TRIM35 | positive regulation of apoptotic process; induction of apoptosis; negative regulation of cell proliferation; negative regulation of mitotic cell cycle | |
| TRIM36 | acrosome reaction | |
| TRIM37 | - | |
| TRIM4 | protein trimerization | |
| TRIM41 | - | |
| TRIM42 | - | |
| TRIM46 | - | |
| TRIM47 | - | |
| TRIM55 | signal transduction | |
| TRIM56 | defense response to virus; response to type I interferon; interferon-beta production; protein K63-linked ubiquitination | |
| TRIM58 | - | |
| TRIM59 | - | |
| TRIM6 | protein trimerization | |
| TRIM60 | - | |
| TRIM62 | - | |
| TRIM63 | signal transduction; proteasomal ubiquitin-dependent protein catabolic process | |
| TRIM65 | - | |
| TRIM68 | protein autoubiquitination; regulation of androgen receptor signaling pathway | |
| TRIM69 | apoptotic process | |
| TRIM7 | - | |
| TRIM71 | multicellular organismal development; cellular response to organic substance | |
| TRIM72 | transport; protein homooligomerization; muscle organ development; exocytosis; muscle system process; plasma membrane repair | |
| TRIM9 | protein ubiquitination; proteasomal ubiquitin-dependent protein catabolic process | |
| TRIO | nerve growth factor receptor signaling pathway; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; regulation of small GTPase mediated signal transduction; apoptotic process; transmembrane receptor protein tyrosine phosphatase signaling pathway; axon guidance; small GTPase mediated signal transduction | |
| TRIOBP | barbed-end actin filament capping; actin modification | |
| TRIP10 | endocytosis; cell communication; signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; actin cytoskeleton organization | |
| TRIP11 | transcription from RNA polymerase II promoter; protein targeting to Golgi | |
| TRIP12 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein ubiquitination; protein modification process | |
| TRIP4 | positive regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| TRIP6 | focal adhesion assembly; positive regulation of cell migration; regulation of transcription, DNA-dependent; cell adhesion; release of cytoplasmic sequestered NF-kappaB | |
| TRMO | interspecies interaction between organisms | |
| TRMT10A | - | |
| TRMT10B | - | |
| TRMT13 | - | |
| TRMT1L | tRNA processing; behavior | |
| TRMT2A | RNA processing | |
| TRMT2B | tRNA processing | |
| TRMT61A | tRNA methylation; tRNA processing | |
| TRMU | tRNA metabolic process; tRNA processing | |
| TRNT1 | tRNA 3'-end processing; protein targeting to mitochondrion; RNA processing | |
| TRO | negative regulation of cell growth; cell adhesion; homophilic cell adhesion; embryo implantation | |
| TROAP | cell adhesion | |
| TROVE2 | transcription from RNA polymerase III promoter | |
| TRPA1 | response to drug; response to cold; ion transport; response to hydrogen peroxide; response to pain; response to stimulus; thermoception; detection of mechanical stimulus involved in sensory perception of pain; detection of chemical stimulus involved in sensory perception of pain | |
| TRPC1 | ion transport; calcium ion transport; axon guidance; positive regulation of release of sequestered calcium ion into cytosol; cytosolic calcium ion homeostasis; calcium ion transmembrane transport; transmembrane transport; response to calcium ion | |
| TRPC3 | calcium ion transport; axon guidance; blood coagulation; phototransduction; calcium ion transmembrane transport; transmembrane transport; ion transport; platelet activation | |
| TRPC4 | transmembrane transport; axon guidance; calcium ion transport; ion transport; calcium ion import | |
| TRPC5 | ion transport; nervous system development; axon guidance; transmembrane transport; calcium ion transport; calcium ion transmembrane transport | |
| TRPC6 | axon guidance; cation transport; elevation of cytosolic calcium ion concentration; blood coagulation; platelet activation; positive regulation of ion transmembrane transporter activity; positive regulation of calcium ion transport via store-operated calcium channel activity | |
| TRPM1 | calcium ion transmembrane transport; transport; ion transport; visual perception; response to stimulus; transmembrane transport; cellular response to light stimulus | |
| TRPM2 | transmembrane transport; calcium ion transmembrane transport; response to hydroperoxide; calcium ion transport; ion transport | |
| TRPM3 | cation transport; transmembrane transport | |
| TRPM4 | protein sumoylation; positive regulation of cell proliferation; ion transport; regulation of T cell cytokine production; transmembrane transport; positive regulation of canonical Wnt receptor signaling pathway; dendritic cell chemotaxis | |
| TRPM5 | ion transport | |
| TRPM6 | protein phosphorylation; ion transport; response to toxin; metal ion transport; transmembrane transport | |
| TRPM7 | calcium-dependent cell-matrix adhesion; transmembrane transport; actomyosin structure organization; protein autophosphorylation; cell death; ion transport | |
| TRPM8 | transmembrane transport; response to stimulus; protein homotetramerization; thermoception; ion transport; cellular calcium ion homeostasis; response to cold; protein homotrimerization | |
| TRPS1 | regulation of chondrocyte differentiation; NLS-bearing substrate import into nucleus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; skeletal system development; negative regulation of transcription from RNA polymerase II promoter | |
| TRPT1 | tRNA splicing, via endonucleolytic cleavage and ligation | |
| TRPV2 | ion transmembrane transport; sensory perception; positive regulation of calcium ion import; transport; positive regulation of axon extension; response to temperature stimulus; response to heat | |
| TRPV3 | response to temperature stimulus; cation transport | |
| TRPV4 | actin filament organization; calcium ion import; calcium ion transport; ion transport; osmosensory signaling pathway; calcium ion transmembrane transport; response to mechanical stimulus; negative regulation of neuron projection development; cellular hypotonic response; positive regulation of microtubule depolymerization; actin cytoskeleton reorganization; cell death; transmembrane transport; elevation of cytosolic calcium ion concentration; cellular calcium ion homeostasis; cell volume homeostasis; cell-cell junction assembly; cortical microtubule organization; microtubule polymerization | |
| TRPV5 | calcium ion transmembrane transport; protein tetramerization; transmembrane transport; calcium ion transport; ion transport | |
| TRPV6 | calcium ion transport; regulation of calcium ion-dependent exocytosis; calcium ion transmembrane transport; ion transport; transmembrane transport | |
| TRRAP | histone H2A acetylation; regulation of transcription, DNA-dependent; chromatin modification; histone acetylation; histone deubiquitination; histone H4 acetylation | |
| TRUB1 | tRNA processing; RNA processing; pseudouridine synthesis | |
| TRUB2 | pseudouridine synthesis; RNA processing; tRNA processing | |
| TSC1 | negative regulation of translation; cell-matrix adhesion; nervous system development; negative regulation of cell proliferation; cell cycle arrest; potassium ion transport; regulation of translation; activation of Rho GTPase activity; insulin receptor signaling pathway; embryo development; regulation of cell-matrix adhesion; hippocampus development; cerebral cortex development; cell projection organization; negative regulation of TOR signaling cascade; rRNA export from nucleus; response to insulin stimulus; kidney development; neural tube closure; regulation of actin cytoskeleton organization; cardiac muscle cell differentiation; positive regulation of focal adhesion assembly; regulation of stress fiber assembly; protein heterooligomerization; protein stabilization; synapse organization; regulation of protein kinase activity; negative regulation of cell size; regulation of phosphoprotein phosphatase activity; myelination | |
| TSC2 | insulin receptor signaling pathway; protein kinase B signaling cascade; negative regulation of MAP kinase activity; negative regulation of TOR signaling cascade; positive regulation of GTPase activity; negative regulation of Wnt receptor signaling pathway; regulation of endocytosis; cell projection organization; vesicle-mediated transport; negative regulation of phosphatidylinositol 3-kinase cascade; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; establishment of protein localization; negative regulation of cell size; regulation of insulin receptor signaling pathway; insulin-like growth factor receptor signaling pathway; negative regulation of protein kinase B signaling cascade; regulation of cell cycle; protein heterooligomerization; protein homooligomerization; regulation of small GTPase mediated signal transduction; positive chemotaxis; negative regulation of epithelial cell proliferation; phosphatidylinositol-mediated signaling; protein localization; n | |
| TSC22D2 | response to osmotic stress | |
| TSC22D3 | body fluid secretion; regulation of transcription, DNA-dependent | |
| TSC22D4 | response to osmotic stress; negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| TSEN15 | tRNA processing; mRNA processing | |
| TSEN2 | tRNA splicing, via endonucleolytic cleavage and ligation; mRNA processing | |
| TSEN34 | tRNA-type intron splice site recognition and cleavage; mRNA processing | |
| TSEN54 | mRNA processing; tRNA splicing, via endonucleolytic cleavage and ligation | |
| TSGA10 | cell projection assembly; spermatogenesis | |
| TSHR | cell-cell signaling; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway; positive regulation of multicellular organism growth; regulation of locomotion; B cell differentiation; adult locomotory behavior; positive regulation of cell proliferation; activation of adenylate cyclase activity by G-protein signaling pathway | |
| TSHZ1 | soft palate development; middle ear morphogenesis; multicellular organismal development; anterior/posterior pattern specification | |
| TSHZ2 | multicellular organismal development | |
| TSHZ3 | negative regulation of transcription, DNA-dependent; multicellular organismal development; regulation of respiratory gaseous exchange by neurological system process | |
| TSKS | negative regulation of phosphatase activity | |
| TSKU | - | |
| TSNAXIP1 | multicellular organismal development; cell differentiation; spermatogenesis | |
| TSPAN1 | - | |
| TSPAN13 | - | |
| TSPAN14 | - | |
| TSPAN16 | - | |
| TSPAN18 | - | |
| TSPAN2 | brain development | |
| TSPAN3 | - | |
| TSPAN31 | positive regulation of cell proliferation | |
| TSPAN33 | - | |
| TSPAN5 | - | |
| TSPAN7 | interspecies interaction between organisms | |
| TSPEAR | cell adhesion | |
| TSPO2 | transport | |
| TSPYL1 | nucleosome assembly | |
| TSR1 | ribosome assembly | |
| TSSC1 | - | |
| TSSC4 | - | |
| TSSK2 | cell differentiation; spermatogenesis; spermatid development; protein autophosphorylation; protein phosphorylation; multicellular organismal development | |
| TSSK6 | protein phosphorylation; multicellular organismal development; spermatogenesis; cell differentiation; sperm chromatin condensation | |
| TST | rRNA transport; sulfide oxidation, using sulfide:quinone oxidoreductase; small molecule metabolic process; rRNA import into mitochondrion; cellular nitrogen compound metabolic process; cyanate catabolic process; sulfur amino acid catabolic process; sulfur amino acid metabolic process | |
| TTBK1 | - | |
| TTBK2 | cell death; peptidyl-serine phosphorylation | |
| TTC12 | - | |
| TTC13 | - | |
| TTC14 | - | |
| TTC16 | - | |
| TTC19 | cell cycle; mitochondrial respiratory chain complex III assembly; cytokinesis | |
| TTC21A | - | |
| TTC21B | - | |
| TTC22 | - | |
| TTC23 | - | |
| TTC26 | - | |
| TTC3 | ubiquitin-dependent protein catabolic process; negative regulation of cell morphogenesis involved in differentiation; negative regulation of neuron differentiation; protein K48-linked ubiquitination | |
| TTC31 | - | |
| TTC32 | - | |
| TTC33 | - | |
| TTC37 | - | |
| TTC38 | - | |
| TTC39B | - | |
| TTC39C | - | |
| TTC7A | hemopoiesis; cellular iron ion homeostasis | |
| TTC7B | - | |
| TTC8 | cell projection organization; cilium assembly; establishment of anatomical structure orientation; sensory processing | |
| TTF1 | regulation of transcription, DNA-dependent; transcription termination, DNA-dependent; chromatin remodeling; transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; negative regulation of DNA replication; gene expression | |
| TTF2 | termination of RNA polymerase II transcription; transcription termination, DNA-dependent; regulation of transcription, DNA-dependent; mRNA processing; RNA splicing | |
| TTK | spindle organization; mitotic spindle organization; mitotic cell cycle spindle assembly checkpoint; positive regulation of cell proliferation; positive regulation of pathway-restricted SMAD protein phosphorylation | |
| TTLL1 | protein polyglutamylation; protein modification process | |
| TTLL10 | protein polyglycylation | |
| TTLL12 | protein modification process | |
| TTLL13P | protein modification process | |
| TTLL4 | protein modification process; protein polyglutamylation | |
| TTLL5 | protein modification process; transcription, DNA-dependent | |
| TTLL7 | protein modification process; multicellular organismal development; cell differentiation; nervous system development | |
| TTLL9 | protein modification process | |
| TTN | regulation of protein kinase activity; platelet degranulation; muscle contraction; striated muscle contraction; mitotic chromosome condensation; blood coagulation; platelet activation; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; response to calcium ion; regulation of catalytic activity; sarcomerogenesis; cardiac muscle fiber development; sarcomere organization; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; muscle filament sliding | |
| TTYH1 | iron ion transmembrane transport; cell adhesion; iron ion transport; ion transport | |
| TTYH2 | ion transport | |
| TTYH3 | chloride transport; ion transport | |
| TUB | response to stimulus; positive regulation of phagocytosis | |
| TUBA1C | microtubule-based movement; protein folding; microtubule-based process; cytoskeleton-dependent intracellular transport; cell division; cellular protein metabolic process; protein polymerization; 'de novo' posttranslational protein folding | |
| TUBA4A | G2/M transition of mitotic cell cycle; mitotic cell cycle; platelet degranulation; protein folding; microtubule-based movement; blood coagulation; platelet activation; cellular protein metabolic process; 'de novo' posttranslational protein folding; protein polymerization | |
| TUBAL3 | microtubule-based movement; protein polymerization | |
| TUBB2B | mitosis; microtubule-based movement; neuron differentiation; cellular protein metabolic process; 'de novo' posttranslational protein folding; protein polymerization; neuron migration; protein folding | |
| TUBB4A | protein folding; microtubule-based movement; cellular protein metabolic process; 'de novo' posttranslational protein folding; protein polymerization; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| TUBB6 | protein folding; microtubule-based movement; cellular protein metabolic process; 'de novo' posttranslational protein folding; protein polymerization | |
| TUBGCP2 | microtubule nucleation; protein complex assembly; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| TUBGCP3 | mitotic cell cycle; microtubule nucleation; single fertilization; G2/M transition of mitotic cell cycle | |
| TUBGCP4 | microtubule nucleation; G2/M transition of mitotic cell cycle; protein complex assembly; mitotic cell cycle | |
| TUBGCP5 | G2/M transition of mitotic cell cycle; mitotic cell cycle; microtubule nucleation | |
| TUBGCP6 | microtubule nucleation; mitotic cell cycle; G2/M transition of mitotic cell cycle | |
| TULP1 | phototransduction; visual perception; G-protein coupled receptor signaling pathway; retina development in camera-type eye; response to stimulus; positive regulation of phagocytosis; photoreceptor cell maintenance; eye photoreceptor cell development; dendrite development | |
| TULP2 | visual perception | |
| TULP3 | regulation of transcription, DNA-dependent; multicellular organismal development; G-protein coupled receptor signaling pathway | |
| TULP4 | response to nutrient; intracellular signal transduction; regulation of transcription, DNA-dependent | |
| TUSC2 | cell cycle; cell-cell signaling; cell proliferation | |
| TUSC3 | protein N-linked glycosylation; cognition; cell redox homeostasis; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; magnesium ion transport; transport | |
| TUT1 | histone mRNA catabolic process; snRNA processing; mRNA cleavage; mRNA polyadenylation | |
| TWF2 | sequestering of actin monomers; positive regulation of axon extension; regulation of actin cytoskeleton organization; positive regulation of neuron projection development; regulation of microvillus length; cellular response to retinoic acid; positive regulation of lamellipodium assembly; negative regulation of actin filament polymerization; barbed-end actin filament capping; cellular response to growth factor stimulus | |
| TWISTNB | - | |
| TXK | positive regulation of interferon-gamma-mediated signaling pathway; positive regulation of interferon-gamma production; interleukin-4 production; activation of phospholipase C activity; protein autophosphorylation; T cell receptor signaling pathway; cytokine production; NK T cell differentiation; adaptive immune response; regulation of transcription from RNA polymerase II promoter; protein phosphorylation | |
| TXLNA | cell proliferation; exocytosis | |
| TXLNB | - | |
| TXLNG | regulation of transcription, DNA-dependent; regulation of cell cycle process; regulation of bone mineralization; regulation of cell cycle | |
| TXNDC16 | cell redox homeostasis | |
| TXNDC2 | cell redox homeostasis; cell differentiation; spermatogenesis; multicellular organismal development; glycerol ether metabolic process; protein thiol-disulfide exchange | |
| TXNDC5 | post-Golgi vesicle-mediated transport; cell redox homeostasis; cellular membrane organization; anti-apoptosis; glycerol ether metabolic process | |
| TXNDC8 | cell redox homeostasis; glycerol ether metabolic process; multicellular organismal development; spermatogenesis; cell differentiation | |
| TXNIP | positive regulation of apoptotic process; cell cycle; innate immune response; response to hydrogen peroxide; platelet-derived growth factor receptor signaling pathway; response to calcium ion; regulation of cell proliferation; negative regulation of cell division; response to mechanical stimulus; cellular response to tumor cell; response to drug; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; protein import into nucleus; response to oxidative stress; response to glucose stimulus; keratinocyte differentiation; response to estradiol stimulus; response to progesterone stimulus; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | |
| TXNL4B | RNA splicing; mitosis; cell cycle; mRNA processing | |
| TYK2 | intracellular protein kinase cascade; protein phosphorylation; cytokine-mediated signaling pathway; type I interferon-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway | |
| TYMP | pyrimidine base metabolic process; DNA replication; pyrimidine nucleotide metabolic process; angiogenesis; mitochondrial genome maintenance; nucleobase-containing small molecule metabolic process; pyrimidine nucleoside catabolic process; small molecule metabolic process; pyrimidine nucleoside salvage; cell differentiation; multicellular organismal development; chemotaxis | |
| TYMS | response to glucocorticoid stimulus; cartilage development; nucleobase-containing small molecule metabolic process; intestinal epithelial cell maturation; developmental growth; phosphatidylinositol-mediated signaling; response to organophosphorus; pyrimidine nucleoside biosynthetic process; dUMP metabolic process; small molecule metabolic process; response to drug; organ regeneration; immortalization of host cell by virus; nucleotide biosynthetic process; deoxyribonucleoside monophosphate biosynthetic process; aging; DNA repair; DNA replication; dTMP biosynthetic process; pyrimidine base metabolic process; nucleobase-containing compound metabolic process; mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle | |
| TYR | visual perception; cell proliferation; pigmentation; thymus development; melanin biosynthetic process from tyrosine; eye pigment biosynthetic process | |
| TYRP1 | pigmentation; melanocyte differentiation; melanin biosynthetic process; acetoacetic acid metabolic process; melanosome organization | |
| TYW5 | tRNA processing; wybutosine biosynthetic process | |
| U2AF1 | mRNA 3'-end processing; gene expression; RNA splicing; mRNA export from nucleus; mRNA processing; termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome | |
| U2AF2 | mRNA processing; gene expression; RNA splicing; mRNA export from nucleus; termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA 3'-end processing; negative regulation of nuclear mRNA splicing, via spliceosome | |
| UACA | - | |
| UAP1 | UDP-N-acetylglucosamine biosynthetic process; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; metabolic process; dolichol-linked oligosaccharide biosynthetic process | |
| UAP1L1 | metabolic process | |
| UBA3 | regulation of cell cycle; negative regulation of transcription, DNA-dependent; protein neddylation; endomitotic cell cycle; proteolysis; protein modification process | |
| UBA6 | protein ubiquitination; ubiquitin-dependent protein catabolic process; protein modification process | |
| UBA7 | innate immune response; negative regulation of type I interferon production; ISG15-protein conjugation; modification-dependent protein catabolic process; cytokine-mediated signaling pathway; protein modification process | |
| UBAC2 | - | |
| UBALD1 | - | |
| UBAP1 | - | |
| UBAP2 | - | |
| UBAP2L | binding of sperm to zona pellucida | |
| UBASH3A | negative regulation of T cell receptor signaling pathway; regulation of cytokine production | |
| UBASH3B | - | |
| UBE2D3 | innate immune response; protein polyubiquitination; DNA repair; protein modification process; ubiquitin-dependent protein catabolic process; protein monoubiquitination; apoptotic process; transforming growth factor beta receptor signaling pathway; protein ubiquitination; BMP signaling pathway; negative regulation of type I interferon production; proteasomal ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein K11-linked ubiquitination | |
| UBE2E2 | ISG15-protein conjugation; protein K11-linked ubiquitination; protein K48-linked ubiquitination; protein K63-linked ubiquitination | |
| UBE2F | protein neddylation | |
| UBE2J1 | - | |
| UBE2J2 | response to unfolded protein | |
| UBE2M | positive regulation of neuron apoptosis; protein modification process; protein ubiquitination; protein neddylation | |
| UBE2O | - | |
| UBE2Q1 | - | |
| UBE2Q2 | protein K48-linked ubiquitination | |
| UBE2U | - | |
| UBE2V2 | cell proliferation; protein ubiquitination; regulation of DNA repair; DNA double-strand break processing; protein polyubiquitination | |
| UBE3A | positive regulation of transcription from RNA polymerase II promoter; protein K48-linked ubiquitination; prostate gland growth; interspecies interaction between organisms; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; androgen receptor signaling pathway; sperm entry; positive regulation of phosphatidylinositol 3-kinase cascade; brain development; ovarian follicle development; protein modification process; proteolysis; ubiquitin-dependent protein catabolic process | |
| UBE3B | protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process | |
| UBE3C | protein modification process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein polyubiquitination | |
| UBE4A | ubiquitin-dependent protein catabolic process | |
| UBE4B | neuron projection development; response to UV; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; cellular protein catabolic process; apoptotic process; response to endoplasmic reticulum stress; ventricular trabecula myocardium morphogenesis; protein polyubiquitination | |
| UBIAD1 | vitamin K biosynthetic process; menaquinone biosynthetic process | |
| UBL3 | - | |
| UBL7 | - | |
| UBN1 | chromatin modification; interspecies interaction between organisms; negative regulation of phosphatase activity; regulation of transcription from RNA polymerase II promoter | |
| UBN2 | - | |
| UBP1 | negative regulation of transcription, DNA-dependent; viral genome replication; regulation of transcription from RNA polymerase II promoter; angiogenesis | |
| UBQLN3 | - | |
| UBQLNL | - | |
| UBR1 | ubiquitin-dependent protein catabolic process; protein catabolic process; negative regulation of TOR signaling cascade; cellular response to leucine | |
| UBR2 | histone H2A ubiquitination; male meiosis I; protein catabolic process; negative regulation of TOR signaling cascade; spermatogenesis; ubiquitin-dependent protein catabolic process; chromatin silencing; cellular response to leucine | |
| UBR4 | interspecies interaction between organisms | |
| UBR5 | positive regulation of canonical Wnt receptor signaling pathway; protein polyubiquitination; progesterone receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of catenin import into nucleus; positive regulation of protein import into nucleus, translocation; protein ubiquitination; cell proliferation; response to DNA damage stimulus; ubiquitin-dependent protein catabolic process; protein modification process | |
| UBTF | transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; gene expression; positive regulation of transcription from RNA polymerase I promoter; regulation of transcription from RNA polymerase I promoter; chromatin silencing at rDNA | |
| UBXN1 | negative regulation of protein ubiquitination; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process | |
| UBXN11 | - | |
| UBXN2B | - | |
| UBXN4 | response to unfolded protein | |
| UBXN7 | - | |
| UCHL1 | protein deubiquitination; cell proliferation; metabolic process; adult walking behavior; axon target recognition; response to stress; ubiquitin-dependent protein catabolic process; proteolysis; cell death; axon transport of mitochondrion; eating behavior; negative regulation of MAP kinase activity; neuromuscular process | |
| UCHL5 | regulation of proteasomal protein catabolic process; negative regulation of endopeptidase activity; ubiquitin-dependent protein catabolic process; DNA repair; DNA recombination; regulation of transcription, DNA-dependent; forebrain morphogenesis; midbrain development; lateral ventricle development; proteolysis; protein deubiquitination | |
| UCK1 | pyrimidine base metabolic process; metabolic process; nucleotide biosynthetic process; pyrimidine nucleoside salvage; small molecule metabolic process; nucleobase-containing small molecule metabolic process | |
| UCK2 | pyrimidine base metabolic process; cellular response to oxygen levels; nucleobase-containing small molecule metabolic process; response to axon injury; small molecule metabolic process; pyrimidine nucleoside salvage; nucleotide biosynthetic process; feeding behavior | |
| UCKL1 | metabolic process; interspecies interaction between organisms | |
| UCMA | negative regulation of osteoblast differentiation | |
| UCP2 | cellular response to insulin stimulus; mitochondrial transport; anion transport; transport; response to hypoxia; response to superoxide; response to glucose stimulus; proton transport; respiratory electron transport chain; cellular response to hormone stimulus; small molecule metabolic process; response to fatty acid | |
| UFC1 | protein ufmylation | |
| UFL1 | protein ufmylation; negative regulation of NF-kappaB transcription factor activity; negative regulation of protein ubiquitination | |
| UFM1 | protein ufmylation | |
| UGCG | sphingolipid metabolic process; small molecule metabolic process; lipid biosynthetic process; glucosylceramide biosynthetic process; glycosphingolipid metabolic process; glycosphingolipid biosynthetic process; epidermis development | |
| UGDH | UDP-glucose metabolic process; glycosaminoglycan biosynthetic process; UDP-glucuronate biosynthetic process; xenobiotic metabolic process; small molecule metabolic process; gastrulation with mouth forming second | |
| UGGT1 | post-translational protein modification; protein folding; 'de novo' posttranslational protein folding; protein glycosylation; cellular protein metabolic process; protein N-linked glycosylation via asparagine | |
| UGGT2 | post-translational protein modification; protein folding; cellular protein metabolic process; protein N-linked glycosylation via asparagine; protein glycosylation | |
| UGT1A6 | metabolic process; small molecule metabolic process; xenobiotic metabolic process | |
| UGT3A2 | metabolic process | |
| UGT8 | neuron projection morphogenesis; paranodal junction assembly; protein localization to paranode region of axon; cytoskeleton organization; axon cargo transport; central nervous system development; peripheral nervous system development; metabolic process | |
| UHRF1BP1 | - | |
| UHRF1BP1L | - | |
| UIMC1 | double-strand break repair; response to ionizing radiation; histone H2A K63-linked deubiquitination; negative regulation of transcription, DNA-dependent; positive regulation of DNA repair; G2/M transition DNA damage checkpoint; chromatin modification | |
| ULK1 | signal transduction; regulation of autophagy; protein localization; axonogenesis; positive regulation of autophagy; protein phosphorylation; neuron projection regeneration; neuron projection development; cellular response to nutrient levels; response to starvation; protein autophosphorylation | |
| ULK4 | - | |
| UMOD | chemical homeostasis; regulation of ion homeostasis; metanephric thick ascending limb development; metanephric distal convoluted tubule development; metanephric ascending thin limb development; response to organic substance; negative regulation of cell proliferation; excretion; cellular defense response | |
| UMODL1 | - | |
| UNC119B | cell projection organization; lipoprotein transport; cilium morphogenesis | |
| UNC13B | signal transduction; excretion; intracellular signal transduction; induction of apoptosis; exocytosis | |
| UNC13D | natural killer cell degranulation; regulation of mast cell degranulation; defense response to virus; phagocytosis; germinal center formation; granuloma formation; secretion; positive regulation of exocytosis | |
| UNC45A | multicellular organismal development; cell differentiation; muscle organ development | |
| UNC45B | cell differentiation; multicellular organismal development; muscle organ development | |
| UNC5B | axon guidance; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; multicellular organismal development; signal transduction; apoptotic process; regulation of apoptotic process | |
| UNC5C | brain development; axon guidance; regulation of cell migration; multicellular organismal development; netrin-activated signaling pathway; signal transduction; apoptotic process | |
| UNC5CL | signal transduction | |
| UNC5D | apoptotic process; multicellular organismal development; axon guidance; signal transduction | |
| UNC79 | - | |
| UNC80 | - | |
| UNKL | - | |
| UPB1 | nitrogen compound metabolic process; pyrimidine base metabolic process; small molecule metabolic process; pyrimidine nucleoside catabolic process; nucleobase-containing small molecule metabolic process | |
| UPF1 | mRNA metabolic process; histone mRNA catabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; DNA replication; DNA repair; mRNA export from nucleus; regulation of translational termination; cell cycle; gene expression; RNA metabolic process | |
| UPF2 | RNA metabolic process; gene expression; mRNA metabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; mRNA export from nucleus | |
| UPF3B | mRNA export from nucleus; nucleocytoplasmic transport; positive regulation of translation; transport; mRNA 3'-end processing; RNA splicing; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; gene expression; termination of RNA polymerase II transcription; RNA metabolic process; mRNA metabolic process | |
| UPK1A | protein oligomerization; epithelial cell differentiation | |
| UPK1B | epithelial cell differentiation | |
| UPP2 | pyrimidine nucleoside catabolic process; nucleotide catabolic process; nucleobase-containing small molecule metabolic process; uridine metabolic process; small molecule metabolic process; pyrimidine nucleoside salvage; nucleoside metabolic process; pyrimidine base metabolic process | |
| UPRT | - | |
| UQCC1 | - | |
| UQCC3 | - | |
| UQCR11 | small molecule metabolic process; proton transport; generation of precursor metabolites and energy; transport; ion transmembrane transport; respiratory electron transport chain | |
| UQCRC1 | response to alkaloid; oxidative phosphorylation; mitochondrial electron transport, ubiquinol to cytochrome c; proteolysis; transport; aerobic respiration; response to activity; respiratory electron transport chain; small molecule metabolic process; oxidation-reduction process | |
| URB2 | - | |
| URGCP | cell cycle | |
| URI1 | negative regulation of transcription from RNA polymerase II promoter; cellular response to steroid hormone stimulus; cellular response to growth factor stimulus; regulation of apoptotic process; negative regulation of phosphatase activity; response to virus; protein folding; regulation of transcription from RNA polymerase II promoter; regulation of cell growth | |
| UROC1 | cellular nitrogen compound metabolic process; histidine catabolic process; small molecule metabolic process | |
| USF1 | lipid homeostasis; regulation of transcription from RNA polymerase II promoter by glucose; positive regulation of transcription from RNA polymerase II promoter by glucose; response to hypoxia; glucose metabolic process; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; response to UV; late viral mRNA transcription; cellular response to insulin stimulus; positive regulation of transcription from RNA polymerase II promoter; carbon catabolite regulation of transcription; negative regulation of fibrinolysis; glucose homeostasis | |
| USF3 | - | |
| USH1C | sensory perception of light stimulus; G2/M transition of mitotic cell cycle; equilibrioception; neuromuscular process controlling balance; sensory perception of sound; parallel actin filament bundle assembly; photoreceptor cell maintenance; inner ear morphogenesis; auditory receptor cell differentiation | |
| USH2A | inner ear receptor cell differentiation; sensory perception of light stimulus; response to stimulus; maintenance of organ identity; photoreceptor cell maintenance; sensory perception of sound | |
| USHBP1 | - | |
| USP1 | protein deubiquitination; monoubiquitinated protein deubiquitination; response to UV; ubiquitin-dependent protein catabolic process; proteolysis; regulation of DNA repair; DNA repair | |
| USP11 | ubiquitin-dependent protein catabolic process; protein deubiquitination; proteolysis | |
| USP12 | protein deubiquitination; protein modification process; proteolysis; ubiquitin-dependent protein catabolic process | |
| USP13 | proteolysis; ubiquitin-dependent protein catabolic process | |
| USP14 | proteolysis; ubiquitin-dependent protein catabolic process; synaptic transmission; negative regulation of endopeptidase activity; regulation of chemotaxis; regulation of proteasomal protein catabolic process | |
| USP16 | cell cycle; proteolysis; positive regulation of transcription, DNA-dependent; protein homotetramerization; ubiquitin-dependent protein catabolic process; chromatin modification; histone deubiquitination; mitosis; cell division | |
| USP19 | regulation of cellular response to hypoxia; response to endoplasmic reticulum stress; regulation of protein stability; ER-associated protein catabolic process; protein deubiquitination; negative regulation of skeletal muscle tissue development; skeletal muscle atrophy; ubiquitin-dependent protein catabolic process; proteolysis; positive regulation of cell cycle process | |
| USP2 | positive regulation of skeletal muscle tissue development; negative regulation of transcription from RNA polymerase II promoter; proteolysis; ubiquitin-dependent protein catabolic process; cell cycle; muscle organ development; protein deubiquitination; positive regulation of mitotic cell cycle; protein stabilization; negative regulation of skeletal muscle tissue development | |
| USP20 | ubiquitin-dependent protein catabolic process; endocytosis; proteolysis; regulation of G-protein coupled receptor protein signaling pathway; protein deubiquitination; protein K48-linked deubiquitination; protein K63-linked deubiquitination | |
| USP21 | proteolysis; protein modification process; chromatin modification; ubiquitin-dependent protein catabolic process; positive regulation of transcription, DNA-dependent; histone deubiquitination | |
| USP25 | proteolysis; protein K48-linked deubiquitination; protein K63-linked deubiquitination; ubiquitin-dependent protein catabolic process; protein modification process | |
| USP26 | ubiquitin-dependent protein catabolic process; proteolysis; protein deubiquitination | |
| USP28 | cell proliferation; response to ionizing radiation; protein deubiquitination; cellular response to UV; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; DNA damage checkpoint; DNA repair; proteolysis; response to DNA damage stimulus; ubiquitin-dependent protein catabolic process | |
| USP29 | protein modification process; proteolysis; ubiquitin-dependent protein catabolic process | |
| USP3 | histone deubiquitination; mitotic cell cycle; DNA repair; proteolysis; ubiquitin-dependent protein catabolic process; chromatin modification; regulation of protein stability | |
| USP30 | ubiquitin-dependent protein catabolic process; proteolysis | |
| USP31 | ubiquitin-dependent protein catabolic process; proteolysis | |
| USP33 | endocytosis; protein K63-linked deubiquitination; axon guidance; regulation of G-protein coupled receptor protein signaling pathway; cell migration; protein K48-linked deubiquitination; ubiquitin-dependent protein catabolic process; protein deubiquitination; proteolysis | |
| USP34 | ubiquitin-dependent protein catabolic process; proteolysis; Wnt receptor signaling pathway; protein K48-linked deubiquitination; positive regulation of canonical Wnt receptor signaling pathway | |
| USP35 | proteolysis; ubiquitin-dependent protein catabolic process | |
| USP36 | ubiquitin-dependent protein catabolic process; proteolysis | |
| USP37 | cell division; protein K48-linked deubiquitination; mitosis; G1/S transition of mitotic cell cycle; proteolysis; ubiquitin-dependent protein catabolic process; cell cycle; protein K11-linked deubiquitination | |
| USP38 | proteolysis; ubiquitin-dependent protein catabolic process | |
| USP4 | proteolysis; ubiquitin-dependent protein catabolic process; protein deubiquitination; regulation of protein stability; protein localization at cell surface; negative regulation of protein ubiquitination | |
| USP44 | ubiquitin-dependent protein catabolic process; proteolysis; cell cycle; mitosis; protein deubiquitination; cell division; anaphase; negative regulation of mitotic anaphase-promoting complex activity; regulation of spindle checkpoint | |
| USP45 | proteolysis; ubiquitin-dependent protein catabolic process | |
| USP48 | proteolysis; ubiquitin-dependent protein catabolic process | |
| USP49 | ubiquitin-dependent protein catabolic process; proteolysis | |
| USP5 | protein K48-linked deubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; proteolysis | |
| USP53 | ubiquitin-dependent protein catabolic process | |
| USP54 | ubiquitin-dependent protein catabolic process | |
| USP7 | proteolysis; protein deubiquitination; multicellular organismal development; induction of apoptosis; ubiquitin-dependent protein catabolic process; regulation of protein stability; interspecies interaction between organisms; regulation of sequence-specific DNA binding transcription factor activity | |
| USP9X | chromosome segregation; female gamete generation; protein deubiquitination; BMP signaling pathway; cell division; transforming growth factor beta receptor signaling pathway; mitosis; cell cycle; ubiquitin-dependent protein catabolic process; proteolysis | |
| USPL1 | ubiquitin-dependent protein catabolic process | |
| UST | protein sulfation | |
| UTP20 | rRNA processing; negative regulation of cell proliferation; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
| UTP23 | rRNA processing | |
| UTP4 | - | |
| UTP6 | rRNA processing; RNA processing | |
| UTRN | muscle organ development; muscle contraction; positive regulation of cell-matrix adhesion | |
| UTS2 | synaptic transmission; regulation of blood pressure; muscle contraction | |
| UTS2R | positive regulation of fibroblast proliferation; negative regulation of urine volume; negative regulation of renal sodium excretion; response to drug; positive regulation of angiogenesis; negative regulation of blood pressure; positive regulation of blood pressure; positive regulation of vasoconstriction; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of cell growth; positive regulation of circadian sleep/wake cycle, wakefulness; blood circulation; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; signal transduction; negative regulation of glomerular filtration | |
| UVRAG | positive regulation of autophagy; DNA repair | |
| VAC14 | signal transduction; interspecies interaction between organisms | |
| VAMP8 | vesicle fusion; cellular membrane organization; protein complex assembly; post-Golgi vesicle-mediated transport | |
| VANGL1 | multicellular organismal development | |
| VANGL2 | establishment or maintenance of epithelial cell apical/basal polarity; apical protein localization; anterior/posterior pattern specification; wound healing; cell migration involved in kidney development; nonmotile primary cilium assembly; somatic stem cell maintenance; regulation of actin cytoskeleton organization; convergent extension involved in neural plate elongation; establishment of planar polarity; somatic stem cell division; planar cell polarity pathway involved in neural tube closure; establishment of planar polarity involved in neural tube closure; cochlea morphogenesis; lateral sprouting involved in lung morphogenesis; establishment of body hair planar orientation; digestive tract morphogenesis; convergent extension involved in axis elongation; inner ear receptor stereocilium organization; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; muscular septum morphogene | |
| VASN | - | |
| VASP | actin cytoskeleton organization; actin polymerization or depolymerization; axon guidance; neural tube closure; cell junction assembly; T cell receptor signaling pathway; protein homotetramerization | |
| VAT1L | - | |
| VAV1 | regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; immune response; positive regulation of cell adhesion; regulation of GTPase activity; T cell activation; T cell costimulation; integrin-mediated signaling pathway; apoptotic process; phagocytosis; regulation of transcription, DNA-dependent; regulation of Rho protein signal transduction; small GTPase mediated signal transduction; blood coagulation; induction of apoptosis by extracellular signals; platelet activation | |
| VAV2 | regulation of catalytic activity; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction; positive regulation of phosphatidylinositol 3-kinase activity; regulation of Rho protein signal transduction; platelet activation; lamellipodium assembly; cell migration; induction of apoptosis by extracellular signals; blood coagulation; axon guidance; small GTPase mediated signal transduction; signal transduction; apoptotic process; angiogenesis | |
| VAV3 | regulation of Rho protein signal transduction; blood coagulation; positive regulation of B cell proliferation; small GTPase mediated signal transduction; response to drug; induction of apoptosis by extracellular signals; cell migration; regulation of catalytic activity; B cell receptor signaling pathway; angiogenesis; regulation of small GTPase mediated signal transduction; integrin-mediated signaling pathway; platelet activation; lamellipodium assembly; positive regulation of GTPase activity; positive regulation of phosphatidylinositol 3-kinase activity; response to DNA damage stimulus; positive regulation of cell adhesion; nerve growth factor receptor signaling pathway; apoptotic process; vesicle fusion | |
| VAX1 | multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; neuron migration; negative regulation of neuroblast proliferation; camera-type eye development; cell differentiation; axon guidance; palate development; brain development | |
| VAX2 | retina development in camera-type eye; axonogenesis; embryonic eye morphogenesis; ectoderm development; multicellular organismal development; visual perception; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; dorsal/ventral axis specification | |
| VCAN | cell adhesion; axon regeneration; response to wounding; glial cell migration; cell recognition; heart development; multicellular organismal development | |
| VCL | cell-matrix adhesion; adherens junction assembly; epithelial cell-cell adhesion; apical junction assembly; protein localization at cell surface; morphogenesis of an epithelium; platelet degranulation; cellular component movement; muscle contraction; cell adhesion; blood coagulation; lamellipodium assembly; platelet activation; regulation of cell migration; negative regulation of cell migration | |
| VCPIP1 | proteolysis; mitosis; endoplasmic reticulum membrane fusion; protein ubiquitination; Golgi reassembly | |
| VCPKMT | - | |
| VDAC1 | learning; behavioral fear response; anion transport; apoptotic process; regulation of ion transmembrane transport; transmembrane transport; interspecies interaction between organisms; regulation of anion transport; neuron-neuron synaptic transmission | |
| VDAC3 | adenine transport; regulation of anion transport; transmembrane transport | |
| VDR | positive regulation of transcription from RNA polymerase II promoter; regulation of calcidiol 1-monooxygenase activity; decidualization; negative regulation of transcription, DNA-dependent; positive regulation of keratinocyte differentiation; positive regulation of vitamin D 24-hydroxylase activity; negative regulation of keratinocyte proliferation; gene expression; negative regulation of cell proliferation; signal transduction; cell morphogenesis; negative regulation of transcription from RNA polymerase II promoter; vitamin D receptor signaling pathway; positive regulation of gene expression | |
| VEGFA | regulation of cell shape; in utero embryonic development; response to cold; positive regulation of endothelial cell migration; positive regulation of intracellular protein kinase cascade; platelet activation; monocyte differentiation; macrophage differentiation; positive regulation of cell migration; epithelial cell differentiation; positive regulation of vascular endothelial growth factor receptor signaling pathway; post-embryonic camera-type eye development; positive regulation of protein autophosphorylation; activation of protein kinase activity; artery morphogenesis; positive regulation of mast cell chemotaxis; mammary gland alveolus development; primitive erythrocyte differentiation; positive regulation of cell division; positive regulation of cellular component movement; induction of positive chemotaxis; positive regulation of positive chemotaxis; positive chemotaxis; positive regulation of peptidyl-tyrosine phosphorylation; cellular response to hypoxia; cardiac muscle fiber development; positive regula | |
| VEGFC | platelet activation; cell differentiation; morphogenesis of embryonic epithelium; organ morphogenesis; positive regulation of cell proliferation; blood coagulation; negative regulation of blood pressure; multicellular organismal development; regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of protein autophosphorylation; response to drug; positive regulation of blood vessel endothelial cell migration; vascular endothelial growth factor receptor signaling pathway; positive regulation of epithelial cell proliferation; positive regulation of protein secretion; positive chemotaxis; induction of positive chemotaxis; positive regulation of cell division; positive regulation of mast cell chemotaxis; substrate-dependent cell migration; platelet degranulation; positive regulation of neuroblast proliferation; angiogenesis; signal transduction | |
| VENTX | multicellular organismal development | |
| VEPH1 | - | |
| VGLL2 | regulation of transcription, DNA-dependent; skeletal muscle tissue development; positive regulation of transcription from RNA polymerase II promoter | |
| VGLL3 | regulation of transcription, DNA-dependent | |
| VHL | proteolysis; negative regulation of cell proliferation; protein stabilization; response to stress; anti-apoptosis; regulation of catecholamine metabolic process; positive regulation of transcription, DNA-dependent; cell morphogenesis; positive regulation of cell differentiation; response to ethanol; blood vessel endothelial cell migration; protein ubiquitination; protein catabolic process; neuron differentiation; extracellular matrix organization; response to hypoxia; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| VIL1 | regulation of actin nucleation; actin filament severing; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to hepatocyte growth factor stimulus; positive regulation of actin filament bundle assembly; positive regulation of cell migration; actin filament depolymerization; actin filament polymerization; negative regulation of endopeptidase activity; positive regulation of epithelial cell migration; response to bacterium; regulation of cell shape; epidermal growth factor receptor signaling pathway; cytoskeleton organization; protein complex assembly; actin filament capping; cytoplasmic actin-based contraction involved in cell motility; regulation of wound healing; cellular response to epidermal growth factor stimulus; regulation of lamellipodium morphogenesis | |
| VIM | apoptotic process; cellular component disassembly involved in apoptosis; muscle filament sliding; cellular component movement; interspecies interaction between organisms | |
| VIP | positive regulation of cell proliferation; body fluid secretion; G-protein coupled receptor signaling pathway | |
| VIPAS39 | - | |
| VIPR2 | signal transduction; G-protein coupled receptor signaling pathway; activation of adenylate cyclase activity; cell-cell signaling | |
| VIT | - | |
| VN1R1 | response to pheromone | |
| VNN1 | chronic inflammatory response; acute inflammatory response; positive regulation of T cell differentiation in thymus; innate immune response; cell-cell adhesion; pantothenate metabolic process; response to oxidative stress; inflammatory response; cellular component movement; anti-apoptosis; nitrogen compound metabolic process | |
| VNN2 | pantothenate metabolic process; cellular component movement; nitrogen compound metabolic process | |
| VPREB1 | immune response | |
| VPS13A | protein transport; Golgi to endosome transport; nervous system development; locomotory behavior; protein localization; social behavior | |
| VPS13B | protein transport; protein localization | |
| VPS13C | protein localization | |
| VPS13D | protein localization | |
| VPS16 | intracellular protein transport | |
| VPS18 | endosome organization; lysosome organization; vesicle-mediated transport; intracellular protein transport | |
| VPS25 | cellular membrane organization; protein transport; regulation of transcription, DNA-dependent; endosome transport | |
| VPS26B | protein transport; vacuolar transport | |
| VPS33A | protein transport; vesicle docking involved in exocytosis; melanosome localization; vesicle-mediated transport; platelet formation; regulation of developmental pigmentation; pigmentation; lysosome localization | |
| VPS33B | platelet alpha granule organization; vesicle docking involved in exocytosis; lysosome localization; melanosome localization; vesicle-mediated transport; cellular membrane fusion; protein transport | |
| VPS35 | retrograde transport, endosome to Golgi; protein transport; cell death | |
| VPS37D | endosome transport; viral reproduction; protein transport; cellular membrane organization; egress of virus within host cell | |
| VPS39 | protein transport | |
| VPS41 | Golgi vesicle transport; vesicle-mediated transport; intracellular protein transport | |
| VPS50 | - | |
| VPS51 | - | |
| VPS53 | protein transport | |
| VPS54 | protein transport; growth; retrograde transport, endosome to Golgi; homeostasis of number of cells within a tissue; musculoskeletal movement; neurofilament cytoskeleton organization | |
| VPS9D1 | - | |
| VRK3 | negative regulation of ERK1 and ERK2 cascade; positive regulation of phosphoprotein phosphatase activity | |
| VSIG4 | negative regulation of T cell proliferation; negative regulation of interleukin-2 production; complement activation, alternative pathway | |
| VSIG8 | - | |
| VSTM1 | - | |
| VSX2 | multicellular organismal development; visual perception; positive regulation of cell proliferation; negative regulation of cell proliferation; camera-type eye development; cell fate commitment; positive regulation of transcription from RNA polymerase II promoter; response to stimulus; retinal bipolar neuron differentiation | |
| VTA1 | endosome transport; protein transport; cellular membrane organization | |
| VTI1A | vesicle fusion with Golgi apparatus; retrograde transport, endosome to Golgi; vesicle-mediated transport; ER to Golgi vesicle-mediated transport; intracellular protein transport | |
| VTN | cell adhesion mediated by integrin; extracellular matrix organization; positive regulation of protein binding; positive regulation of vascular endothelial growth factor receptor signaling pathway; immune response; positive regulation of receptor-mediated endocytosis; positive regulation of peptidyl-tyrosine phosphorylation; smooth muscle cell-matrix adhesion; positive regulation of wound healing; negative regulation of blood coagulation; positive regulation of smooth muscle cell migration; negative regulation of endopeptidase activity; positive regulation of cell-substrate adhesion; cell-matrix adhesion; cell adhesion | |
| VWA3B | - | |
| VWA5A | - | |
| VWA8 | - | |
| VWCE | - | |
| VWF | blood coagulation; blood coagulation, intrinsic pathway; cell-substrate adhesion; hemostasis; response to wounding; platelet activation; cell adhesion; platelet degranulation; placenta development; liver development; protein homooligomerization | |
| WAPL | cell cycle; mitosis; negative regulation of DNA replication; response to toxin; negative regulation of chromatin binding; interspecies interaction between organisms; negative regulation of sister chromatid cohesion; cell division; regulation of cohesin localization to chromatin; protein localization to chromatin | |
| WARS | gene expression; tRNA aminoacylation for protein translation; tryptophanyl-tRNA aminoacylation; negative regulation of cell proliferation; translation; regulation of angiogenesis | |
| WASF2 | lamellipodium assembly; actin cytoskeleton organization; Rac protein signal transduction; actin filament-based movement; G-protein signaling, coupled to cAMP nucleotide second messenger; endocytosis; ameboidal cell migration; angiogenesis | |
| WASF3 | protein complex assembly; cytoskeleton organization; regulation of cell shape; actin filament polymerization | |
| WBP1L | - | |
| WBP2 | - | |
| WBP2NL | meiosis; egg activation; male pronucleus assembly | |
| WBP4 | nuclear mRNA cis splicing, via spliceosome; mRNA processing; RNA splicing | |
| WBSCR17 | - | |
| WBSCR22 | methylation; metabolic process | |
| WBSCR27 | - | |
| WDFY1 | - | |
| WDFY2 | - | |
| WDFY3 | metabolic process | |
| WDPCP | regulation of protein localization; cell projection organization; regulation of embryonic cell shape; septin cytoskeleton organization; cilium morphogenesis | |
| WDR11 | - | |
| WDR12 | rRNA processing; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal large subunit biogenesis; Notch signaling pathway; cell proliferation | |
| WDR17 | - | |
| WDR20 | - | |
| WDR24 | - | |
| WDR25 | - | |
| WDR26 | - | |
| WDR3 | - | |
| WDR31 | - | |
| WDR33 | spermatogenesis; mRNA processing; postreplication repair | |
| WDR35 | cell projection organization; cilium assembly | |
| WDR36 | rRNA processing; visual perception; response to stimulus | |
| WDR37 | - | |
| WDR38 | - | |
| WDR4 | tRNA modification | |
| WDR47 | - | |
| WDR48 | protein deubiquitination; interspecies interaction between organisms | |
| WDR49 | - | |
| WDR5 | histone H3 acetylation; skeletal system development; regulation of transcription, DNA-dependent; chromatin modification; histone H3-K4 methylation; histone H4-K16 acetylation; histone H4-K8 acetylation; histone H4-K5 acetylation | |
| WDR54 | - | |
| WDR55 | rRNA processing | |
| WDR59 | - | |
| WDR5B | - | |
| WDR6 | cell cycle arrest; negative regulation of cell proliferation; cell cycle | |
| WDR62 | neurogenesis; cerebral cortex development | |
| WDR63 | - | |
| WDR64 | - | |
| WDR66 | - | |
| WDR7 | - | |
| WDR72 | - | |
| WDR75 | - | |
| WDR81 | negative regulation of phosphatase activity | |
| WDR90 | - | |
| WDR91 | - | |
| WDSUB1 | - | |
| WEE2 | female meiosis; mitosis; meiotic prophase I; meiotic metaphase II; egg activation; female pronucleus assembly; regulation of meiosis I; negative regulation of oocyte development | |
| WFDC1 | negative regulation of epithelial cell proliferation; response to drug; response to estradiol stimulus; negative regulation of cell growth | |
| WFDC10A | - | |
| WFDC3 | - | |
| WFDC5 | - | |
| WFDC6 | - | |
| WFIKKN1 | - | |
| WFIKKN2 | transforming growth factor beta receptor signaling pathway | |
| WHSC1 | chromatin modification; anatomical structure morphogenesis; regulation of transcription, DNA-dependent | |
| WHSC1L1 | chromatin modification; histone lysine methylation; cell growth; regulation of transcription, DNA-dependent; cell differentiation; histone methylation | |
| WIF1 | Wnt receptor signaling pathway; positive regulation of fat cell differentiation; signal transduction; multicellular organismal development | |
| WIPF2 | - | |
| WIPI1 | macroautophagy; endoplasmic reticulum unfolded protein response; vesicle targeting, trans-Golgi to endosome; activation of signaling protein activity involved in unfolded protein response; autophagy | |
| WIPI2 | autophagic vacuole assembly; autophagic vacuole fusion; autophagy | |
| WISP1 | regulation of cell growth; cell adhesion; signal transduction; cell-cell signaling; Wnt receptor signaling pathway | |
| WISP2 | negative regulation of cell proliferation; cell-cell signaling; signal transduction; cell adhesion; regulation of cell growth | |
| WISP3 | regulation of cell growth; signal transduction; cell-cell signaling | |
| WLS | multicellular organismal development; Wnt receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of canonical Wnt receptor signaling pathway | |
| WNK1 | regulation of cellular process; neuron development; protein phosphorylation; negative regulation of phosphatase activity; ion transport; intracellular protein kinase cascade | |
| WNK3 | intracellular protein kinase cascade; anti-apoptosis; protein phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of sodium ion transport; positive regulation of ion transmembrane transporter activity; positive regulation of establishment of protein localization in plasma membrane; sodium ion export; regulation of ion homeostasis; positive regulation of sodium ion transmembrane transporter activity; positive regulation of rubidium ion transport; positive regulation of calcium ion transport; protein autophosphorylation; positive regulation of rubidium ion transmembrane transporter activity; rubidium ion transport | |
| WNT10B | protein stabilization; multicellular organismal development; negative regulation of epithelial cell proliferation; skeletal muscle fiber development; sensory perception of taste; regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of skeletal muscle tissue development; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; positive regulation of osteoblast differentiation; negative regulation of fat cell differentiation; tongue development; positive regulation of apoptotic process; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of protein metabolic process; positive regulation of anagen; canonical Wnt receptor signaling pathway; bone trabecula formation; fungiform papilla development; cellular response to retinoic acid; cellular response to cAMP; cellular response to parathyroid hormone stimulus; cellular response to organic cyclic compound; hemopoietic stem cell proliferation; cellular response t | |
| WNT11 | protein localization at cell surface; positive regulation of transforming growth factor beta2 production; positive regulation of Ras GTPase activity; negative regulation of cell migration; positive regulation of cell migration; adrenal gland development; negative regulation of cell growth; bone mineralization; neuron differentiation; embryonic skeletal system development; Wnt receptor signaling pathway; non-canonical Wnt receptor signaling pathway; positive regulation of apoptotic process; negative regulation of apoptotic process; negative regulation of transcription, DNA-dependent; mesonephric duct development; negative regulation of mesenchymal cell proliferation; positive regulation of protein kinase C signaling cascade; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of fibroblast growth factor production; positive regulation of transcription, DNA-dependent; neuroendocrine cell differentiation; artery morphogenesis; positive regulation of stress fiber assembly; palate | |
| WNT16 | keratinocyte differentiation; cardiac epithelial to mesenchymal transition; canonical Wnt receptor signaling pathway; positive regulation of JNK cascade; keratinocyte proliferation; negative regulation of cell death; positive regulation of gene expression; oxidative stress-induced premature senescence; positive regulation of phosphatidylinositol 3-kinase cascade; replicative senescence; optic cup formation involved in camera-type eye development; multicellular organismal development; axonogenesis; axis specification; anterior/posterior pattern specification | |
| WNT2B | male gonad development; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of branching involved in ureteric bud morphogenesis; hemopoietic stem cell proliferation; cornea development in camera-type eye; iris morphogenesis; mesenchymal-epithelial cell signaling; lung induction; neuron differentiation; forebrain regionalization; Wnt receptor signaling pathway; dorsal/ventral axis specification; multicellular organismal development; Wnt receptor signaling pathway, calcium modulating pathway; lens development in camera-type eye; chondrocyte differentiation | |
| WNT3A | embryonic pattern specification; positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation; axis specification; anatomical structure morphogenesis; positive regulation of cell proliferation; mesoderm development; axon guidance; axonogenesis; determination of left/right symmetry; multicellular organismal development; cell-cell signaling; Wnt receptor signaling pathway, calcium modulating pathway; negative regulation of heart induction by canonical Wnt receptor signaling pathway; positive regulation of receptor internalization; heart looping; positive regulation of protein phosphorylation; somitogenesis; in utero embryonic development; osteoblast differentiation; positive regulation of protein binding; paraxial mesodermal cell fate commitment; positive regulation of protein tyrosine kinase activity; canonical Wnt receptor signaling pathway; convergent extension; palate development; positive regulation of sequence-specific DNA binding transcripti | |
| WNT4 | epithelial to mesenchymal transition; embryonic epithelial tube formation; kidney development; renal vesicle induction; mesonephros development; thyroid-stimulating hormone-secreting cell differentiation; liver development; somatotropin secreting cell differentiation; branching involved in ureteric bud morphogenesis; mesenchymal to epithelial transition; tertiary branching involved in mammary gland duct morphogenesis; mammary gland epithelium development; positive regulation of dermatome development; paramesonephric duct development; metanephros development; negative regulation of testicular blood vessel morphogenesis; cellular response to estradiol stimulus; establishment of protein localization in plasma membrane; metanephric nephron morphogenesis; cellular response to hydrostatic pressure; cellular response to transforming growth factor beta stimulus; renal vesicle formation; negative regulation of cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of testosteron | |
| WNT5B | respiratory system development; negative regulation of canonical Wnt receptor signaling pathway; cellular response to retinoic acid; lens fiber cell development; angiogenesis; chondrocyte differentiation; Wnt receptor signaling pathway, calcium modulating pathway; multicellular organismal development; dorsal/ventral axis specification; anterior/posterior pattern specification; Wnt receptor signaling pathway; neuron differentiation; positive regulation of cell migration; endocrine pancreas development; cell migration involved in gastrulation; fat cell differentiation; positive regulation of fat cell differentiation; convergent extension involved in gastrulation; convergent extension involved in axis elongation | |
| WNT6 | cornea development in camera-type eye; positive regulation of tooth mineralization; cellular response to retinoic acid; nephron tubule formation; nephron tubule development; cell-cell signaling; branching involved in ureteric bud morphogenesis; positive regulation of transcription, DNA-dependent; branching morphogenesis of a tube; canonical Wnt receptor signaling pathway; epithelial-mesenchymal cell signaling; odontogenesis of dentin-containing tooth; neuron differentiation; positive regulation of gene expression; anterior/posterior pattern specification; axis specification; multicellular organismal development | |
| WNT7A | negative regulation of neurogenesis; skin morphogenesis; response to estrogen stimulus; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of JNK cascade; somatic stem cell division; skeletal system morphogenesis; stem cell development; negative regulation of apoptotic process; synapse organization; cartilage development; positive regulation of synapse assembly; palate development; positive regulation of epithelial cell proliferation involved in wound healing; uterus development; oviduct development; canonical Wnt receptor signaling pathway; limb development; uterus morphogenesis; lens fiber cell development; cellular response to transforming growth factor beta stimulus; positive regulation of canonical Wnt receptor signaling pathway; regulation of cell proliferation; embryonic digit morphogenesis; embryonic axis specification; skeletal system development; signal transduction; activation of JUN kinase activity; neurotr | |
| WNT7B | central nervous system vasculogenesis; neuron differentiation; lung development; oxygen homeostasis; odontogenesis of dentin-containing tooth; odontogenesis; cellular metabolic process; positive regulation of osteoblast differentiation; negative regulation of smoothened signaling pathway; positive regulation of JNK cascade; fibroblast proliferation; embryonic organ development; stem cell development; negative regulation of neurogenesis; synapse organization; smooth muscle cell differentiation; axonogenesis; homeostatic process; in utero embryonic development; vasculature development; metanephros morphogenesis; induction of apoptosis; activation of JUN kinase activity; cell-cell signaling; multicellular organismal development; forebrain regionalization; positive regulation of cell proliferation; axis specification; anterior/posterior pattern specification; positive regulation of gene expression; Wnt receptor signaling pathway; establishment or maintenance of polarity of embryonic epithelium; cell proliferation | |
| WNT8B | canonical Wnt receptor signaling pathway; determination of dorsal identity; otic placode formation; response to retinoic acid; response to estradiol stimulus; neuron differentiation; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway; cellular response to retinoic acid; Wnt receptor signaling pathway involved in forebrain neuron fate commitment; hypothalamus development; negative regulation of gene expression; positive regulation of gene expression; anterior/posterior pattern specification; axis specification; endoderm development; nervous system development; gastrulation; multicellular organismal development; signal transduction; eye development | |
| WNT9A | multicellular organismal development; cell-cell signaling; embryonic skeletal joint development; cellular response to retinoic acid; cornea development in camera-type eye; iris morphogenesis; canonical Wnt receptor signaling pathway; embryonic skeletal system morphogenesis; positive regulation of smoothened signaling pathway; negative regulation of chondrocyte differentiation; mitotic cell cycle G1/S transition checkpoint; neuron differentiation; anterior/posterior pattern specification; axis specification; negative regulation of cell proliferation; endoderm development; embryonic arm morphogenesis | |
| WRAP53 | telomere formation via telomerase; positive regulation of telomerase activity | |
| WRN | nucleobase-containing compound metabolic process; positive regulation of hydrolase activity; cellular metabolic process; regulation of apoptotic process; regulation of growth rate; DNA duplex unwinding; nucleolus to nucleoplasm transport; replication fork processing; multicellular organismal aging; response to UV-C; cellular response to starvation; cell aging; response to oxidative stress; aging; replicative cell aging; DNA synthesis involved in DNA repair; telomere maintenance; ATP catabolic process; DNA metabolic process; DNA replication; base-excision repair; DNA recombination; response to DNA damage stimulus | |
| WRNIP1 | DNA synthesis involved in DNA repair; ATP catabolic process; DNA replication; regulation of DNA-dependent DNA replication initiation | |
| WSB1 | intracellular signal transduction | |
| WSCD1 | - | |
| WSCD2 | - | |
| WT1 | negative regulation of metanephric glomerular mesangial cell proliferation; positive regulation of male gonad development; negative regulation of female gonad development; positive regulation of metanephric ureteric bud development; regulation of transcription, DNA-dependent; regulation of organ formation; mesonephros development; kidney development; branching involved in ureteric bud morphogenesis; ureteric bud development; vasculogenesis; negative regulation of transcription from RNA polymerase II promoter; metanephric S-shaped body morphogenesis; negative regulation of cell proliferation; glomerular basement membrane development; glomerulus development; regulation of transcription from RNA polymerase II promoter; induction of apoptosis; germ cell development; thorax and anterior abdomen determination; heart development; sex determination; adrenal cortex formation; RNA splicing; gonad development; male gonad development; tissue development; negative regulation of translation; negative regulation of cell gro | |
| WWC1 | regulation of hippo signaling cascade; cell migration; regulation of transcription, DNA-dependent; positive regulation of MAPK cascade | |
| WWP1 | interspecies interaction between organisms; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of transcription, DNA-dependent; entry of virus into host cell; central nervous system development; protein ubiquitination; protein modification process; signal transduction | |
| WWP2 | negative regulation of sequence-specific DNA binding transcription factor activity; interspecies interaction between organisms; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of transporter activity; protein ubiquitination; negative regulation of gene expression; protein modification process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; entry of virus into host cell; negative regulation of protein transport; protein K63-linked ubiquitination | |
| WWTR1 | stem cell division; glomerulus development; positive regulation of epithelial to mesenchymal transition; positive regulation of cell proliferation; negative regulation of protein kinase activity; hippo signaling cascade; negative regulation of catenin import into nucleus; regulation of transcription, DNA-dependent; negative regulation of protein phosphorylation; osteoblast differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cilium morphogenesis; regulation of SMAD protein import into nucleus; negative regulation of canonical Wnt receptor signaling pathway | |
| XAF1 | apoptotic process; cytokine-mediated signaling pathway; type I interferon-mediated signaling pathway | |
| XCR1 | chemotaxis; release of sequestered calcium ion into cytosol; response to cytokine stimulus; elevation of cytosolic calcium ion concentration; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway; inflammatory response | |
| XDH | small molecule metabolic process; purine base metabolic process; purine nucleotide catabolic process; lactation; xanthine catabolic process; nucleobase-containing small molecule metabolic process; regulation of epithelial cell differentiation | |
| XIRP1 | cardiac muscle cell development; sarcomere organization; negative regulation of cell proliferation; actin cytoskeleton organization; regulation of membrane potential | |
| XIRP2 | actin cytoskeleton organization | |
| XKR6 | - | |
| XKR9 | - | |
| XPNPEP1 | proteolysis; bradykinin catabolic process; cellular process | |
| XPO1 | viral genome transport in host cell; mRNA transport; interspecies interaction between organisms; viral infectious cycle; mRNA metabolic process; RNA metabolic process; gene expression; intracellular protein transport; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle; viral reproduction | |
| XPO4 | protein transport; positive regulation of protein export from nucleus | |
| XPO6 | protein export from nucleus; intracellular protein transport | |
| XPOT | intracellular protein transport; transport; tRNA export from nucleus | |
| XRCC1 | base-excision repair; response to drug; response to organic substance; DNA repair; response to hypoxia; single strand break repair | |
| XRCC4 | central nervous system development; isotype switching; response to X-ray; response to gamma radiation; viral reproduction; provirus integration; initiation of viral infection; T cell differentiation in thymus; immunoglobulin V(D)J recombination; negative regulation of neuron apoptosis; double-strand break repair via nonhomologous end joining; DNA repair; pro-B cell differentiation; in utero embryonic development; positive regulation of fibroblast proliferation; positive regulation of neurogenesis; DNA ligation involved in DNA repair; positive regulation of ligase activity; double-strand break repair; cellular response to lithium ion | |
| XRCC5 | viral reproduction; provirus integration; initiation of viral infection; negative regulation of transcription, DNA-dependent; negative regulation of apoptotic process; cell proliferation; DNA recombination; double-strand break repair via nonhomologous end joining; double-strand break repair; DNA repair; telomere maintenance; positive regulation of neurogenesis; hemopoietic stem cell differentiation | |
| XRCC6 | negative regulation of transcription, DNA-dependent; viral reproduction; provirus integration; initiation of viral infection; V(D)J recombination; DNA repair; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neurogenesis; response to ionizing radiation; double-strand break repair via nonhomologous end joining; double-strand break repair; telomere maintenance; DNA ligation | |
| XRCC6BP1 | proteolysis; double-strand break repair via nonhomologous end joining | |
| XYLT1 | cellular response to heat; response to interleukin-1; negative regulation of axon regeneration; proteoglycan biosynthetic process; glycosaminoglycan biosynthetic process | |
| XYLT2 | glycosaminoglycan biosynthetic process | |
| YARS2 | tRNA aminoacylation for protein translation; translation; gene expression; tRNA aminoacylation; mitochondrial tyrosyl-tRNA aminoacylation | |
| YEATS2 | histone H3 acetylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent | |
| YIPF2 | - | |
| YKT6 | ER to Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; protein transport; vesicle docking involved in exocytosis; vesicle targeting | |
| YME1L1 | protein catabolic process; proteolysis | |
| YPEL2 | - | |
| YPEL5 | oxidation-reduction process | |
| YRDC | negative regulation of transport | |
| YTHDC2 | - | |
| YTHDF1 | - | |
| YWHAG | protein targeting; regulation of signal transduction; regulation of neuron differentiation; negative regulation of protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of synaptic plasticity | |
| YWHAH | glucocorticoid catabolic process; intracellular protein transport; glucocorticoid receptor signaling pathway; regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; regulation of synaptic plasticity; negative regulation of dendrite morphogenesis | |
| YY2 | regulation of transcription, DNA-dependent | |
| ZACN | response to zinc ion; ion transport | |
| ZADH2 | - | |
| ZAP70 | T cell differentiation; T cell receptor signaling pathway; T cell activation; B cell activation; positive thymic T cell selection; intracellular protein kinase cascade; immune response; positive regulation of T cell differentiation; T cell aggregation; protein phosphorylation; adaptive immune response; T cell migration | |
| ZAR1 | sodium ion transport; multicellular organismal development | |
| ZBBX | - | |
| ZBED4 | - | |
| ZBED8 | - | |
| ZBP1 | innate immune response | |
| ZBTB1 | regulation of transcription, DNA-dependent | |
| ZBTB11 | regulation of transcription, DNA-dependent | |
| ZBTB14 | - | |
| ZBTB16 | positive regulation of apoptotic process; forelimb morphogenesis; embryonic hindlimb morphogenesis; positive regulation of chondrocyte differentiation; myeloid cell differentiation; hemopoiesis; anterior/posterior pattern specification; positive regulation of fat cell differentiation; embryonic pattern specification; negative regulation of cell proliferation; mesonephros development; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; male germ-line stem cell division; cartilage development; positive regulation of cartilage development; positive regulation of ossification; apoptotic process; central nervous system development; negative regulation of myeloid cell differentiation | |
| ZBTB18 | - | |
| ZBTB2 | regulation of transcription, DNA-dependent | |
| ZBTB20 | regulation of transcription, DNA-dependent | |
| ZBTB21 | - | |
| ZBTB24 | regulation of transcription, DNA-dependent | |
| ZBTB25 | gene expression; regulation of transcription, DNA-dependent | |
| ZBTB26 | regulation of transcription, DNA-dependent | |
| ZBTB3 | regulation of transcription, DNA-dependent | |
| ZBTB32 | transcription from RNA polymerase II promoter; hemopoiesis; T cell proliferation; regulation of transcription, DNA-dependent; DNA repair; regulation of cytokine production; negative regulation of transcription from RNA polymerase II promoter | |
| ZBTB33 | regulation of transcription, DNA-dependent; Wnt receptor signaling pathway; intracellular signal transduction | |
| ZBTB39 | regulation of transcription, DNA-dependent | |
| ZBTB4 | regulation of transcription, DNA-dependent | |
| ZBTB40 | regulation of transcription, DNA-dependent; response to DNA damage stimulus; bone mineralization | |
| ZBTB41 | regulation of transcription, DNA-dependent | |
| ZBTB43 | regulation of transcription, DNA-dependent | |
| ZBTB48 | regulation of transcription, DNA-dependent | |
| ZBTB49 | regulation of transcription, DNA-dependent | |
| ZBTB6 | regulation of transcription, DNA-dependent | |
| ZBTB7B | transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; cell differentiation; multicellular organismal development; ectoderm development | |
| ZBTB7C | - | |
| ZC2HC1C | - | |
| ZC3H10 | - | |
| ZC3H13 | - | |
| ZC3H14 | - | |
| ZC3H18 | - | |
| ZC3H3 | regulation of mRNA export from nucleus; mRNA polyadenylation; poly(A)+ mRNA export from nucleus | |
| ZC3H4 | - | |
| ZC3H7A | - | |
| ZC3H7B | interspecies interaction between organisms | |
| ZC3HAV1 | response to virus; regulation of defense response to virus by host | |
| ZCCHC11 | RNA 3'-end processing; regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of NF-kappaB transcription factor activity; positive regulation of interleukin-6 production; gene silencing by RNA; interleukin-6-mediated signaling pathway; pre-miRNA processing; stem cell maintenance; miRNA catabolic process; miRNA metabolic process; cytokine production; histone mRNA catabolic process | |
| ZCCHC12 | regulation of transcription, DNA-dependent | |
| ZCCHC13 | - | |
| ZCCHC6 | RNA 3'-end processing; histone mRNA catabolic process | |
| ZCCHC7 | - | |
| ZCRB1 | RNA splicing; mRNA processing | |
| ZCWPW1 | - | |
| ZDHHC1 | protein palmitoylation | |
| ZDHHC11 | - | |
| ZDHHC14 | - | |
| ZDHHC19 | - | |
| ZDHHC21 | regulation of nitric-oxide synthase activity; nitric oxide metabolic process; small molecule metabolic process | |
| ZDHHC4 | - | |
| ZDHHC5 | - | |
| ZDHHC7 | - | |
| ZDHHC8 | - | |
| ZEB1 | regulation of transcription from RNA polymerase II promoter; immune response; response to activity; forebrain development; negative regulation of epithelial cell differentiation; cell differentiation; regulation of transforming growth factor beta receptor signaling pathway; response to nutrient levels; regulation of T cell differentiation in thymus; negative regulation of transcription from RNA polymerase II promoter; cellular response to transforming growth factor beta stimulus; cellular response to amino acid stimulus; cartilage development; regulation of smooth muscle cell differentiation; embryonic skeletal system morphogenesis; cell proliferation; positive regulation of neuron differentiation; negative regulation of transcription, DNA-dependent; pattern specification process; nervous system development; central nervous system development; negative regulation of cell proliferation; regulation of mesenchymal cell proliferation; positive regulation of transcription from RNA polymerase II promoter; embryonic | |
| ZEB2 | cell proliferation in forebrain; positive regulation of Wnt receptor signaling pathway; hippocampus development; central nervous system development; nervous system development; neural tube closure; somitogenesis; neural crest cell migration; positive regulation of JUN kinase activity; embryonic morphogenesis | |
| ZFAND1 | - | |
| ZFAND3 | - | |
| ZFAND4 | - | |
| ZFAT | regulation of transcription, DNA-dependent | |
| ZFC3H1 | RNA processing | |
| ZFP14 | regulation of transcription, DNA-dependent | |
| ZFP2 | regulation of transcription, DNA-dependent | |
| ZFP28 | regulation of transcription, DNA-dependent | |
| ZFP3 | regulation of transcription, DNA-dependent | |
| ZFP36 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; 3'-UTR-mediated mRNA stabilization; response to stress; RNA destabilization; negative regulation of inflammatory response; negative regulation of myeloid cell differentiation; regulation of mRNA stability; regulation of tumor necrosis factor production; mRNA metabolic process; RNA metabolic process; gene expression; intracellular protein kinase cascade; negative regulation of transcription from RNA polymerase II promoter; mRNA catabolic process | |
| ZFP37 | regulation of transcription, DNA-dependent; cell proliferation; cell differentiation | |
| ZFP41 | cell differentiation; regulation of transcription, DNA-dependent; multicellular organismal development; spermatogenesis | |
| ZFP42 | regulation of transcription, DNA-dependent; female gonad development; male gonad development; meiosis | |
| ZFP64 | regulation of transcription, DNA-dependent | |
| ZFP69B | - | |
| ZFP82 | regulation of transcription, DNA-dependent | |
| ZFP90 | positive regulation of transcription, DNA-dependent; negative regulation of DNA binding | |
| ZFP91 | protein K63-linked ubiquitination; activation of NF-kappaB-inducing kinase activity | |
| ZFPL1 | regulation of transcription, DNA-dependent; vesicle-mediated transport | |
| ZFPM1 | negative regulation of transcription from RNA polymerase II promoter; T-helper cell lineage commitment; negative regulation of protein binding; embryonic hemopoiesis; platelet formation; megakaryocyte differentiation; erythrocyte differentiation; positive regulation of interferon-gamma biosynthetic process; regulation of definitive erythrocyte differentiation; blood coagulation; heart development; regulation of transcription, DNA-dependent; tricuspid valve formation; mitral valve formation; atrioventricular valve morphogenesis; outflow tract morphogenesis; negative regulation of interleukin-4 biosynthetic process; negative regulation of fat cell differentiation; cardiac muscle tissue morphogenesis; primitive erythrocyte differentiation; negative regulation of mast cell differentiation; ventricular septum morphogenesis; atrial septum morphogenesis; transcriptional activation by promoter-enhancer looping | |
| ZFR | multicellular organismal development | |
| ZFYVE1 | negative regulation of phosphatase activity | |
| ZFYVE16 | endosome transport; vesicle organization; signal transduction; protein targeting to lysosome; regulation of endocytosis; BMP signaling pathway | |
| ZFYVE21 | - | |
| ZFYVE26 | DNA repair; cytokinesis; double-strand break repair via homologous recombination; cell death; cell cycle | |
| ZFYVE27 | protein localization in plasma membrane; nerve growth factor receptor signaling pathway; neuron projection development; cell death | |
| ZFYVE28 | negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor-activated receptor activity | |
| ZFYVE9 | endocytosis; transforming growth factor beta receptor signaling pathway; SMAD protein complex assembly; SMAD protein import into nucleus | |
| ZGPAT | negative regulation of epidermal growth factor-activated receptor activity; negative regulation of transcription, DNA-dependent | |
| ZHX1 | negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent | |
| ZHX3 | negative regulation of transcription, DNA-dependent; positive regulation of osteoblast differentiation | |
| ZIC1 | spinal cord development; cell differentiation; positive regulation of protein import into nucleus; regulation of smoothened signaling pathway; behavior; brain development; pattern specification process; regulation of transcription, DNA-dependent; inner ear morphogenesis; positive regulation of transcription, DNA-dependent | |
| ZIC2 | negative regulation of transcription, DNA-dependent; neural tube closure; multicellular organismal development; brain development; visual perception; cell differentiation; retinal ganglion cell axon guidance; positive regulation of transcription, DNA-dependent; developmental pigmentation; positive regulation of sequence-specific DNA binding transcription factor activity | |
| ZIC5 | multicellular organismal development; nervous system development; cell differentiation | |
| ZIK1 | regulation of transcription, DNA-dependent | |
| ZIM3 | regulation of transcription, DNA-dependent | |
| ZKSCAN1 | viral reproduction; regulation of transcription, DNA-dependent | |
| ZKSCAN2 | viral reproduction | |
| ZKSCAN4 | viral reproduction | |
| ZKSCAN5 | viral reproduction; regulation of transcription, DNA-dependent | |
| ZKSCAN7 | - | |
| ZKSCAN8 | - | |
| ZMAT4 | - | |
| ZMIZ1 | vasculogenesis; artery morphogenesis; in utero embryonic development; developmental growth; positive regulation of fibroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; cell aging; vitellogenesis; regulation of transcription, DNA-dependent; heart morphogenesis | |
| ZMIZ2 | positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| ZMPSTE24 | nuclear envelope organization; prenylated protein catabolic process; proteolysis; metabolic process | |
| ZMYM1 | - | |
| ZMYM3 | regulation of cell morphogenesis; multicellular organismal development; cytoskeleton organization | |
| ZMYM4 | cytoskeleton organization; multicellular organismal development; regulation of cell morphogenesis | |
| ZMYM5 | - | |
| ZMYM6 | regulation of cell morphogenesis; multicellular organismal development; cytoskeleton organization | |
| ZMYND10 | - | |
| ZMYND11 | regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; cell cycle; cell proliferation; negative regulation of I-kappaB kinase/NF-kappaB cascade; interspecies interaction between organisms; negative regulation of JNK cascade; negative regulation of extrinsic apoptotic signaling pathway | |
| ZMYND15 | cell differentiation; spermatogenesis; regulation of transcription, DNA-dependent | |
| ZMYND8 | negative regulation of transcription from RNA polymerase II promoter | |
| ZNF10 | regulation of transcription, DNA-dependent | |
| ZNF106 | - | |
| ZNF112 | regulation of transcription, DNA-dependent | |
| ZNF114 | regulation of transcription, DNA-dependent | |
| ZNF121 | regulation of transcription, DNA-dependent | |
| ZNF132 | regulation of transcription, DNA-dependent | |
| ZNF133 | regulation of transcription, DNA-dependent | |
| ZNF136 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter | |
| ZNF138 | regulation of transcription, DNA-dependent | |
| ZNF14 | regulation of transcription, DNA-dependent | |
| ZNF141 | anatomical structure morphogenesis; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent | |
| ZNF142 | regulation of transcription, DNA-dependent | |
| ZNF143 | gene expression; transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase III promoter; regulation of transcription from RNA polymerase II promoter | |
| ZNF146 | regulation of transcription, DNA-dependent | |
| ZNF148 | negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein complex assembly; cellular defense response; gamete generation; negative regulation of gene expression | |
| ZNF155 | regulation of transcription, DNA-dependent | |
| ZNF157 | negative regulation of transcription from RNA polymerase II promoter | |
| ZNF16 | regulation of transcription, DNA-dependent | |
| ZNF160 | hemopoiesis; regulation of transcription, DNA-dependent | |
| ZNF165 | viral reproduction; regulation of transcription, DNA-dependent | |
| ZNF169 | regulation of transcription, DNA-dependent | |
| ZNF17 | regulation of transcription, DNA-dependent | |
| ZNF175 | regulation of transcription, DNA-dependent; response to virus | |
| ZNF18 | viral reproduction | |
| ZNF180 | regulation of transcription, DNA-dependent | |
| ZNF184 | regulation of transcription, DNA-dependent | |
| ZNF19 | regulation of transcription, DNA-dependent | |
| ZNF195 | regulation of transcription, DNA-dependent | |
| ZNF197 | regulation of transcription, DNA-dependent; viral reproduction | |
| ZNF2 | regulation of transcription, DNA-dependent | |
| ZNF200 | regulation of transcription, DNA-dependent | |
| ZNF202 | negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; lipid metabolic process; viral reproduction | |
| ZNF205 | regulation of transcription, DNA-dependent | |
| ZNF211 | regulation of transcription, DNA-dependent | |
| ZNF212 | regulation of transcription, DNA-dependent | |
| ZNF217 | transcription, DNA-dependent; regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent | |
| ZNF22 | regulation of transcription, DNA-dependent; odontogenesis | |
| ZNF221 | regulation of transcription, DNA-dependent | |
| ZNF222 | regulation of transcription, DNA-dependent | |
| ZNF223 | regulation of transcription, DNA-dependent | |
| ZNF224 | negative regulation of transcription, DNA-dependent | |
| ZNF229 | regulation of transcription, DNA-dependent | |
| ZNF23 | regulation of transcription, DNA-dependent | |
| ZNF233 | regulation of transcription, DNA-dependent | |
| ZNF236 | regulation of transcription, DNA-dependent; cellular response to glucose stimulus | |
| ZNF239 | regulation of transcription, DNA-dependent | |
| ZNF248 | regulation of transcription, DNA-dependent | |
| ZNF25 | regulation of transcription, DNA-dependent | |
| ZNF256 | multicellular organismal development; regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent | |
| ZNF263 | negative regulation of transcription, DNA-dependent; viral reproduction; regulation of transcription, DNA-dependent | |
| ZNF264 | regulation of transcription, DNA-dependent | |
| ZNF267 | regulation of transcription, DNA-dependent; multicellular organismal development | |
| ZNF276 | regulation of transcription, DNA-dependent | |
| ZNF28 | regulation of transcription, DNA-dependent | |
| ZNF280A | regulation of transcription, DNA-dependent | |
| ZNF280B | regulation of transcription, DNA-dependent | |
| ZNF280C | regulation of transcription, DNA-dependent | |
| ZNF280D | regulation of transcription, DNA-dependent | |
| ZNF281 | positive regulation of transcription, DNA-dependent; negative regulation of gene expression; negative regulation of transcription, DNA-dependent | |
| ZNF282 | regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent | |
| ZNF287 | regulation of cytokine biosynthetic process; positive regulation of transcription, DNA-dependent; viral reproduction | |
| ZNF296 | spermatogenesis; regulation of transcription, DNA-dependent | |
| ZNF3 | regulation of transcription, DNA-dependent; cell differentiation; multicellular organismal development; leukocyte activation | |
| ZNF300 | regulation of transcription, DNA-dependent | |
| ZNF317 | regulation of transcription, DNA-dependent | |
| ZNF318 | meiosis; regulation of transcription, DNA-dependent | |
| ZNF319 | regulation of transcription, DNA-dependent | |
| ZNF320 | regulation of transcription, DNA-dependent | |
| ZNF324 | regulation of transcription, DNA-dependent | |
| ZNF326 | regulation of transcription, DNA-dependent | |
| ZNF331 | regulation of transcription, DNA-dependent | |
| ZNF333 | regulation of transcription, DNA-dependent | |
| ZNF334 | regulation of transcription, DNA-dependent | |
| ZNF335 | regulation of transcription, DNA-dependent | |
| ZNF337 | regulation of transcription, DNA-dependent | |
| ZNF341 | regulation of transcription, DNA-dependent | |
| ZNF343 | regulation of transcription, DNA-dependent | |
| ZNF345 | negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter; regulation of transcription from RNA polymerase III promoter; transcription from RNA polymerase II promoter | |
| ZNF347 | regulation of transcription, DNA-dependent | |
| ZNF350 | negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| ZNF354C | regulation of transcription, DNA-dependent | |
| ZNF358 | regulation of transcription, DNA-dependent; stem cell maintenance; neural tube development; embryonic forelimb morphogenesis | |
| ZNF365 | - | |
| ZNF366 | response to estrogen stimulus; regulation of transcription, DNA-dependent; negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter | |
| ZNF367 | regulation of transcription from RNA polymerase II promoter | |
| ZNF382 | negative regulation of transcription, DNA-dependent | |
| ZNF383 | regulation of transcription, DNA-dependent | |
| ZNF385A | regulation of transcription, DNA-dependent | |
| ZNF394 | viral reproduction | |
| ZNF395 | regulation of transcription, DNA-dependent | |
| ZNF397 | viral reproduction | |
| ZNF398 | positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent | |
| ZNF408 | regulation of transcription, DNA-dependent | |
| ZNF41 | regulation of transcription, DNA-dependent | |
| ZNF415 | regulation of transcription, DNA-dependent | |
| ZNF416 | regulation of transcription, DNA-dependent | |
| ZNF418 | regulation of transcription, DNA-dependent | |
| ZNF420 | regulation of transcription, DNA-dependent | |
| ZNF423 | nervous system development; negative regulation of transcription, DNA-dependent; positive regulation of BMP signaling pathway; multicellular organismal development; positive regulation of transcription, DNA-dependent; cell differentiation; Notch signaling pathway | |
| ZNF425 | negative regulation of transcription, DNA-dependent | |
| ZNF426 | regulation of transcription, DNA-dependent | |
| ZNF43 | regulation of transcription, DNA-dependent | |
| ZNF431 | regulation of transcription, DNA-dependent | |
| ZNF436 | regulation of transcription, DNA-dependent | |
| ZNF438 | negative regulation of transcription, DNA-dependent | |
| ZNF439 | regulation of transcription, DNA-dependent | |
| ZNF441 | regulation of transcription, DNA-dependent | |
| ZNF445 | viral reproduction | |
| ZNF446 | viral reproduction | |
| ZNF449 | viral reproduction | |
| ZNF45 | regulation of transcription, DNA-dependent; multicellular organismal development; gene expression | |
| ZNF451 | regulation of transcription, DNA-dependent | |
| ZNF454 | regulation of transcription, DNA-dependent | |
| ZNF462 | regulation of transcription, DNA-dependent; negative regulation of DNA binding; positive regulation of transcription from RNA polymerase II promoter | |
| ZNF467 | regulation of transcription, DNA-dependent | |
| ZNF470 | regulation of transcription, DNA-dependent | |
| ZNF471 | regulation of transcription, DNA-dependent | |
| ZNF473 | gene expression; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; termination of RNA polymerase II transcription; mRNA processing; histone mRNA 3'-end processing; histone mRNA metabolic process | |
| ZNF474 | - | |
| ZNF48 | regulation of transcription, DNA-dependent | |
| ZNF480 | regulation of transcription, DNA-dependent | |
| ZNF483 | viral reproduction | |
| ZNF484 | regulation of transcription, DNA-dependent | |
| ZNF485 | regulation of transcription, DNA-dependent | |
| ZNF490 | regulation of transcription, DNA-dependent | |
| ZNF491 | regulation of transcription, DNA-dependent | |
| ZNF502 | regulation of transcription, DNA-dependent | |
| ZNF503 | regulation of transcription, DNA-dependent | |
| ZNF507 | regulation of transcription, DNA-dependent | |
| ZNF511 | regulation of transcription, DNA-dependent | |
| ZNF512 | regulation of transcription, DNA-dependent | |
| ZNF512B | regulation of transcription, DNA-dependent | |
| ZNF513 | regulation of transcription, DNA-dependent; retina development in camera-type eye; response to stimulus; visual perception | |
| ZNF514 | regulation of transcription, DNA-dependent | |
| ZNF517 | regulation of transcription, DNA-dependent | |
| ZNF518B | regulation of transcription, DNA-dependent | |
| ZNF521 | cell differentiation; multicellular organismal development; regulation of transcription, DNA-dependent | |
| ZNF524 | regulation of transcription, DNA-dependent | |
| ZNF526 | regulation of transcription, DNA-dependent | |
| ZNF527 | regulation of transcription, DNA-dependent | |
| ZNF528 | regulation of transcription, DNA-dependent | |
| ZNF530 | regulation of transcription, DNA-dependent | |
| ZNF536 | negative regulation of neuron differentiation; negative regulation of retinoic acid receptor signaling pathway; regulation of transcription, DNA-dependent | |
| ZNF540 | regulation of transcription, DNA-dependent | |
| ZNF544 | regulation of transcription, DNA-dependent | |
| ZNF546 | regulation of transcription, DNA-dependent | |
| ZNF547 | regulation of transcription, DNA-dependent | |
| ZNF549 | regulation of transcription, DNA-dependent | |
| ZNF551 | regulation of transcription, DNA-dependent | |
| ZNF554 | regulation of transcription, DNA-dependent | |
| ZNF555 | regulation of transcription, DNA-dependent | |
| ZNF556 | regulation of transcription, DNA-dependent | |
| ZNF557 | regulation of transcription, DNA-dependent | |
| ZNF559 | regulation of transcription, DNA-dependent | |
| ZNF560 | regulation of transcription, DNA-dependent | |
| ZNF564 | regulation of transcription, DNA-dependent | |
| ZNF565 | regulation of transcription, DNA-dependent | |
| ZNF566 | regulation of transcription, DNA-dependent | |
| ZNF567 | regulation of transcription, DNA-dependent | |
| ZNF568 | regulation of transcription, DNA-dependent | |
| ZNF569 | regulation of transcription, DNA-dependent | |
| ZNF570 | regulation of transcription, DNA-dependent | |
| ZNF571 | regulation of transcription, DNA-dependent | |
| ZNF572 | regulation of transcription, DNA-dependent | |
| ZNF573 | regulation of transcription, DNA-dependent | |
| ZNF574 | regulation of transcription, DNA-dependent | |
| ZNF577 | regulation of transcription, DNA-dependent | |
| ZNF581 | regulation of transcription, DNA-dependent | |
| ZNF582 | regulation of transcription, DNA-dependent | |
| ZNF584 | regulation of transcription, DNA-dependent | |
| ZNF585A | regulation of transcription, DNA-dependent | |
| ZNF585B | regulation of transcription, DNA-dependent | |
| ZNF586 | regulation of transcription, DNA-dependent | |
| ZNF589 | regulation of transcription, DNA-dependent | |
| ZNF592 | regulation of transcription, DNA-dependent; cell death | |
| ZNF594 | regulation of transcription, DNA-dependent | |
| ZNF599 | regulation of transcription, DNA-dependent | |
| ZNF606 | regulation of transcription, DNA-dependent | |
| ZNF607 | regulation of transcription, DNA-dependent | |
| ZNF608 | - | |
| ZNF609 | - | |
| ZNF610 | regulation of transcription, DNA-dependent | |
| ZNF615 | regulation of transcription, DNA-dependent | |
| ZNF616 | regulation of transcription, DNA-dependent | |
| ZNF619 | regulation of transcription, DNA-dependent | |
| ZNF621 | regulation of transcription, DNA-dependent | |
| ZNF622 | positive regulation of JNK cascade; positive regulation of MAPK cascade; positive regulation of apoptotic process; positive regulation of kinase activity; induction of apoptosis by oxidative stress | |
| ZNF623 | regulation of transcription, DNA-dependent | |
| ZNF625 | regulation of transcription, DNA-dependent | |
| ZNF627 | regulation of transcription, DNA-dependent | |
| ZNF630 | regulation of transcription, DNA-dependent | |
| ZNF638 | RNA splicing; regulation of transcription, DNA-dependent | |
| ZNF641 | regulation of transcription, DNA-dependent | |
| ZNF644 | regulation of transcription, DNA-dependent | |
| ZNF645 | - | |
| ZNF646 | regulation of transcription, DNA-dependent | |
| ZNF648 | regulation of transcription, DNA-dependent | |
| ZNF649 | regulation of transcription, DNA-dependent | |
| ZNF652 | regulation of transcription, DNA-dependent | |
| ZNF653 | regulation of transcription, DNA-dependent | |
| ZNF655 | G1 phase; regulation of mitotic cell cycle; regulation of transcription, DNA-dependent | |
| ZNF660 | regulation of transcription, DNA-dependent | |
| ZNF662 | regulation of transcription, DNA-dependent | |
| ZNF664 | regulation of transcription, DNA-dependent | |
| ZNF667 | regulation of transcription, DNA-dependent | |
| ZNF668 | regulation of transcription, DNA-dependent | |
| ZNF669 | regulation of transcription, DNA-dependent | |
| ZNF670 | regulation of transcription, DNA-dependent | |
| ZNF671 | regulation of transcription, DNA-dependent | |
| ZNF672 | regulation of transcription, DNA-dependent | |
| ZNF675 | regulation of transcription, DNA-dependent; bone resorption; negative regulation of JUN kinase activity; negative regulation of NF-kappaB transcription factor activity; cytokine-mediated signaling pathway; negative regulation of tumor necrosis factor-mediated signaling pathway; I-kappaB kinase/NF-kappaB cascade; negative regulation of JNK cascade; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription regulatory region DNA binding; negative regulation of interleukin-1-mediated signaling pathway; negative regulation of osteoclast differentiation | |
| ZNF677 | regulation of transcription, DNA-dependent | |
| ZNF678 | regulation of transcription, DNA-dependent | |
| ZNF682 | regulation of transcription, DNA-dependent | |
| ZNF684 | regulation of transcription, DNA-dependent | |
| ZNF687 | regulation of transcription, DNA-dependent | |
| ZNF691 | - | |
| ZNF696 | regulation of transcription, DNA-dependent | |
| ZNF699 | regulation of transcription, DNA-dependent | |
| ZNF7 | regulation of transcription, DNA-dependent; multicellular organismal development | |
| ZNF70 | regulation of transcription, DNA-dependent | |
| ZNF701 | regulation of transcription, DNA-dependent | |
| ZNF703 | negative regulation of homotypic cell-cell adhesion; mammary gland epithelial cell differentiation; positive regulation of mammary gland epithelial cell proliferation; positive regulation of cell migration; regulation of transforming growth factor beta receptor signaling pathway; positive regulation of epithelial to mesenchymal transition; positive regulation of cell proliferation; regulation of transcription, DNA-dependent; regulation of canonical Wnt receptor signaling pathway; adherens junction assembly; negative regulation of transcription, DNA-dependent; regulation of cell cycle | |
| ZNF704 | - | |
| ZNF71 | regulation of transcription, DNA-dependent | |
| ZNF710 | regulation of transcription, DNA-dependent | |
| ZNF711 | positive regulation of transcription, DNA-dependent | |
| ZNF713 | regulation of transcription, DNA-dependent | |
| ZNF74 | regulation of transcription, DNA-dependent; multicellular organismal development | |
| ZNF746 | neuron death; regulation of cell death; negative regulation of transcription, DNA-dependent | |
| ZNF750 | - | |
| ZNF76 | regulation of transcription from RNA polymerase III promoter; regulation of transcription from RNA polymerase II promoter | |
| ZNF764 | regulation of transcription, DNA-dependent | |
| ZNF774 | regulation of transcription, DNA-dependent | |
| ZNF775 | regulation of transcription, DNA-dependent | |
| ZNF777 | regulation of transcription, DNA-dependent | |
| ZNF780A | regulation of transcription, DNA-dependent | |
| ZNF785 | regulation of transcription, DNA-dependent | |
| ZNF787 | regulation of transcription, DNA-dependent | |
| ZNF791 | regulation of transcription, DNA-dependent | |
| ZNF8 | negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; BMP signaling pathway | |
| ZNF80 | regulation of transcription, DNA-dependent | |
| ZNF800 | regulation of transcription, DNA-dependent | |
| ZNF804A | - | |
| ZNF804B | - | |
| ZNF81 | regulation of transcription, DNA-dependent | |
| ZNF816 | regulation of transcription, DNA-dependent | |
| ZNF827 | regulation of transcription, DNA-dependent | |
| ZNF829 | regulation of transcription, DNA-dependent | |
| ZNF83 | regulation of transcription, DNA-dependent | |
| ZNF831 | - | |
| ZNF846 | regulation of transcription, DNA-dependent | |
| ZNF85 | regulation of transcription, DNA-dependent | |
| ZNF91 | regulation of transcription, DNA-dependent | |
| ZNF92 | regulation of transcription, DNA-dependent | |
| ZNFX1 | - | |
| ZNHIT3 | regulation of transcription, DNA-dependent | |
| ZNHIT6 | box C/D snoRNP assembly; ribosome biogenesis | |
| ZNRF2 | - | |
| ZNRF3 | - | |
| ZP2 | binding of sperm to zona pellucida; single fertilization; intracellular protein transport; manganese ion transport; regulation of acrosome reaction | |
| ZPLD1 | - | |
| ZPR1 | signal transduction; cell proliferation | |
| ZRANB1 | cytoskeleton organization; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; protein K63-linked deubiquitination; positive regulation of Wnt receptor signaling pathway; regulation of cell morphogenesis; cell migration; proteolysis | |
| ZSCAN10 | viral reproduction; negative regulation of transcription, DNA-dependent | |
| ZSCAN18 | viral reproduction | |
| ZSCAN2 | cell differentiation; viral reproduction; spermatogenesis; multicellular organismal development | |
| ZSCAN20 | viral reproduction | |
| ZSCAN21 | regulation of transcription, DNA-dependent; viral reproduction; positive regulation of transcription, DNA-dependent | |
| ZSCAN25 | - | |
| ZSCAN29 | viral reproduction | |
| ZSCAN30 | viral reproduction | |
| ZSCAN31 | - | |
| ZSCAN32 | - | |
| ZSCAN4 | viral reproduction; telomere maintenance via telomere lengthening | |
| ZSCAN9 | - | |
| ZSWIM1 | - | |
| ZSWIM3 | - | |
| ZSWIM4 | - | |
| ZSWIM5 | - | |
| ZW10 | protein complex assembly; cell division; protein localization to kinetochore; vesicle-mediated transport; protein transport; meiosis; regulation of exit from mitosis; mitotic cell cycle checkpoint; mitotic metaphase plate congression; ER to Golgi vesicle-mediated transport; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle; mitotic sister chromatid segregation; establishment of mitotic spindle orientation | |
| ZWILCH | cell division; mitotic cell cycle checkpoint; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle | |
| ZYG11B | - | |
| ZYX | interspecies interaction between organisms; cell-cell signaling; signal transduction; cell adhesion | |
| ZZEF1 | - | |