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CellMiner Address: https://discover.nci.nih.gov/cellminer/
CellMiner Database Version: 2.5
Human Genome Version: HG-19
Date: 01-26-2021
Table 5: Genes with protein function affecting genetic variant data
Gene symbolAnnotation
A1CFprotein stabilization; mRNA modification; cytidine to uridine editing; gene expression; mRNA processing
A2ML1negative regulation of peptidase activity; regulation of endopeptidase activity
A4GALTlipid biosynthetic process; plasma membrane organization; glycosphingolipid biosynthetic process
A4GNTglycoprotein biosynthetic process; protein O-linked glycosylation; carbohydrate metabolic process
AAAStransmembrane transport; regulation of nucleocytoplasmic transport; small molecule metabolic process; cytokine-mediated signaling pathway; viral reproduction; glucose transport; regulation of glucose transport; carbohydrate metabolic process; nucleocytoplasmic transport; learning; hexose transport; fertilization
AACSpositive regulation of insulin secretion; cellular response to testosterone stimulus; cellular response to glucose stimulus; adipose tissue development; white fat cell differentiation; response to ethanol; response to starvation; response to drug; response to oleic acid; response to purine-containing compound; response to organic nitrogen; response to nutrient; fatty acid metabolic process; cellular response to cholesterol; lipid metabolic process; liver development
AADACL2metabolic process
AADACL3metabolic process
AADACL4metabolic process
AADATglutamate metabolic process; 2-oxoglutarate metabolic process; lysine catabolic process; tryptophan catabolic process; biosynthetic process; tryptophan catabolic process to kynurenine; cellular nitrogen compound metabolic process; small molecule metabolic process; kynurenine metabolic process
AAMPangiogenesis; cell differentiation; smooth muscle cell migration; positive regulation of endothelial cell migration; multicellular organismal development
AAR2-
AARStRNA aminoacylation for protein translation; protein folding; neuromuscular process controlling balance; negative regulation of neuron apoptosis; response to amino acid stimulus; endoplasmic reticulum unfolded protein response; skin development; cerebellar Purkinje cell layer development; gene expression; alanyl-tRNA aminoacylation; tRNA processing; hair follicle development; tRNA modification
AARS2tRNA aminoacylation for protein translation; alanyl-tRNA aminoacylation; gene expression
AASDHPPTvitamin metabolic process; small molecule metabolic process; water-soluble vitamin metabolic process; macromolecule biosynthetic process; pantothenate metabolic process
AASSlysine catabolic process; L-lysine catabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process; protein tetramerization
AATFresponse to DNA damage stimulus; positive regulation of transcription from RNA polymerase II promoter; negative regulation of amyloid precursor protein biosynthetic process; ribosome biogenesis; embryonic cleavage; negative regulation of superoxide anion generation; induction of apoptosis by extracellular signals; regulation of mitotic cell cycle; cell adhesion; anti-apoptosis; apoptotic process; nerve growth factor receptor signaling pathway; negative regulation of reactive oxygen species metabolic process
ABCA1endosome transport; positive regulation of cAMP biosynthetic process; intracellular cholesterol transport; Cdc42 protein signal transduction; cholesterol efflux; phospholipid efflux; high-density lipoprotein particle assembly; cellular response to retinoic acid; response to laminar fluid shear stress; apolipoprotein A-I-mediated signaling pathway; lipoprotein metabolic process; cholesterol homeostasis; cellular response to lipopolysaccharide; platelet dense granule organization; response to low-density lipoprotein particle stimulus; phospholipid homeostasis; interleukin-1 beta secretion; phospholipid translocation; anion transport; small molecule metabolic process; cellular lipid metabolic process; reverse cholesterol transport; positive regulation of cholesterol efflux; peptide secretion; protein lipidation; lipid metabolic process; transport; phagocytosis, engulfment; G-protein coupled receptor signaling pathway; steroid metabolic process; cholesterol metabolic process; negative regulation of macrophage der
ABCA10transport
ABCA12cellular homeostasis; lipid transport; transport
ABCA2ATP catabolic process; regulation of transcription from RNA polymerase II promoter; lipid metabolic process; transport; regulation of intracellular cholesterol transport; response to drug; cholesterol homeostasis; response to steroid hormone stimulus
ABCA3response to drug; transport; transmembrane transport
ABCA4transmembrane transport; response to stimulus; photoreceptor cell maintenance; phospholipid transfer to membrane; transport; visual perception; phototransduction, visible light
ABCA5reverse cholesterol transport; transport; high-density lipoprotein particle remodeling; cholesterol efflux; negative regulation of macrophage derived foam cell differentiation
ABCA6transport
ABCA7phagocytosis; phospholipid efflux; transmembrane transport
ABCA8transport; transmembrane transport
ABCA9transport
ABCB1stem cell proliferation; transmembrane transport; response to drug; transport; G2/M transition of mitotic cell cycle
ABCB10transport; transmembrane transport
ABCB4lipid metabolic process; transport; response to drug; cellular lipid metabolic process; small molecule metabolic process; response to glucocorticoid stimulus; transmembrane transport
ABCB5transmembrane transport; regulation of membrane potential
ABCB6transport; porphyrin-containing compound biosynthetic process; cellular iron ion homeostasis; heme transport; transmembrane transport; cadmium ion transmembrane transport; detoxification of cadmium ion
ABCC1transmembrane transport; small molecule metabolic process; response to drug; leukotriene biosynthetic process; transport; prostanoid metabolic process; ATP catabolic process
ABCC10transmembrane transport
ABCC11transmembrane transport
ABCC12transmembrane transport
ABCC2transport; organic anion transport; transmembrane transport
ABCC3transport; bile acid metabolic process; transmembrane transport; small molecule metabolic process; bile acid and bile salt transport; organic anion transport
ABCC4platelet degranulation; transmembrane transport; platelet activation; blood coagulation; ion transport
ABCC6transmembrane transport; response to stimulus; response to drug; visual perception; transport
ABCC8carbohydrate metabolic process; potassium ion transmembrane transport; transmembrane transport; regulation of insulin secretion; negative regulation of insulin secretion; small molecule metabolic process; positive regulation of potassium ion transport; response to drug; response to lipopolysaccharide; response to zinc ion; response to pH; synaptic transmission; potassium ion transport; energy reserve metabolic process; response to insulin stimulus
ABCC9transmembrane transport; defense response to virus; potassium ion import; synaptic transmission; potassium ion transport
ABCD1peroxisomal long-chain fatty acid import; peroxisomal membrane transport; fatty acid beta-oxidation using acyl-CoA oxidase; cellular lipid metabolic process; peroxisome organization; small molecule metabolic process; transmembrane transport; ATP catabolic process
ABCD2transmembrane transport; positive regulation of fatty acid beta-oxidation; very long-chain fatty acid metabolic process
ABCD3ATP catabolic process; response to drug; transmembrane transport
ABCD4transmembrane transport
ABCG1glycoprotein transport; cholesterol metabolic process; detection of hormone stimulus; response to organic substance; negative regulation of macrophage derived foam cell differentiation; regulation of cholesterol esterification; positive regulation of cholesterol efflux; negative regulation of cholesterol storage; phospholipid transport; intracellular cholesterol transport; cholesterol efflux; phospholipid efflux; response to lipid; low-density lipoprotein particle remodeling; high-density lipoprotein particle remodeling; lipoprotein metabolic process; cholesterol homeostasis; amyloid precursor protein catabolic process; reverse cholesterol transport; small molecule metabolic process; positive regulation of cholesterol biosynthetic process; transmembrane transport; phospholipid homeostasis; response to high density lipoprotein particle stimulus; lipid metabolic process; regulation of transcription, DNA-dependent
ABCG2cellular iron ion homeostasis; transmembrane transport; heme transport; response to drug; urate metabolic process; transport
ABCG4cholesterol efflux; transmembrane transport
ABCG5cholesterol efflux; intestinal cholesterol absorption; response to drug; cholesterol homeostasis; excretion; response to nutrient; lipid metabolic process; ATP catabolic process; sterol transport; negative regulation of intestinal phytosterol absorption; response to ionizing radiation; transmembrane transport; small molecule metabolic process; negative regulation of intestinal cholesterol absorption
ABCG8ATP catabolic process; lipid metabolic process; transmembrane transport; negative regulation of intestinal cholesterol absorption; small molecule metabolic process; cholesterol homeostasis; cholesterol efflux; intestinal cholesterol absorption; sterol transport; phospholipid transport; negative regulation of intestinal phytosterol absorption; excretion
ABHD1-
ABHD12-
ABHD12B-
ABHD14A-
ABHD15-
ABHD16B-
ABHD2response to wounding; negative regulation of cell migration
ABHD6regulation of endocannabinoid signaling pathway; long term synaptic depression; negative regulation of cell migration
ABHD8-
ABI1negative regulation of cell proliferation; actin polymerization or depolymerization; cellular component movement; somitogenesis; peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
ABI2peptidyl-tyrosine phosphorylation; cellular component movement; cytoskeleton organization; actin polymerization or depolymerization; cell migration
ABL1regulation of transcription, DNA-dependent; regulation of transcription involved in S phase of mitotic cell cycle; regulation of response to DNA damage stimulus; regulation of actin cytoskeleton reorganization; regulation of cell motility; negative regulation of protein serine/threonine kinase activity; positive regulation of oxidoreductase activity; positive regulation of muscle cell differentiation; positive regulation of apoptotic process; signal transduction in response to DNA damage; muscle cell differentiation; regulation of cell adhesion; regulation of endocytosis; actin cytoskeleton organization; peptidyl-tyrosine phosphorylation; regulation of autophagy; DNA damage response, signal transduction resulting in induction of apoptosis; blood coagulation; axon guidance; DNA damage induced protein phosphorylation; protein modification process; mismatch repair
ABL2regulation of actin cytoskeleton reorganization; regulation of cell motility; cellular response to retinoic acid; regulation of cell adhesion; protein modification process; protein phosphorylation; signal transduction; axon guidance; positive regulation of oxidoreductase activity; regulation of autophagy; positive regulation of neuron projection development; peptidyl-tyrosine phosphorylation; regulation of endocytosis
ABLIM1cytoskeleton organization; axon guidance; visual perception; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter
ABLIM3positive regulation of transcription from RNA polymerase II promoter; axon guidance; cytoskeleton organization
ABRApositive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of Rho protein signal transduction; protein transport; protein import into nucleus, translocation
ABRACL-
ABTB1-
ABTB2regulation of cell growth
ACAA2anti-apoptosis; cholesterol biosynthetic process; fatty acid beta-oxidation; fatty acid metabolic process; lipid metabolic process; acetyl-CoA metabolic process
ACACAsmall molecule metabolic process; protein homotetramerization; lipid homeostasis; response to organic cyclic compound; cellular lipid metabolic process; response to drug; long-chain fatty-acyl-CoA biosynthetic process; tissue homeostasis; acetyl-CoA metabolic process; energy reserve metabolic process; fatty acid biosynthetic process; triglyceride biosynthetic process; positive regulation of cellular metabolic process; multicellular organismal protein metabolic process
ACACBprotein homotetramerization; regulation of fatty acid oxidation; small molecule metabolic process; cellular lipid metabolic process; positive regulation of cellular metabolic process; carnitine shuttle; fatty acid biosynthetic process; energy reserve metabolic process; acetyl-CoA metabolic process
ACAD10-
ACAD11fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACAD8small molecule metabolic process; cellular nitrogen compound metabolic process; branched chain family amino acid catabolic process; lipid metabolic process; regulation of transcription, DNA-dependent
ACADLtemperature homeostasis; regulation of cholesterol metabolic process; oxidation-reduction process; protein homotetramerization; negative regulation of fatty acid oxidation; small molecule metabolic process; negative regulation of fatty acid biosynthetic process; fatty acid metabolic process; fatty acid beta-oxidation; carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA dehydrogenase; carnitine catabolic process; long-chain fatty acid catabolic process; cellular lipid metabolic process; cellular lipid catabolic process
ACADMcarnitine biosynthetic process; medium-chain fatty acid metabolic process; medium-chain fatty acid catabolic process; oxidation-reduction process; fatty acid beta-oxidation; carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA dehydrogenase; small molecule metabolic process; cellular lipid metabolic process
ACADSsmall molecule metabolic process; response to glucocorticoid stimulus; protein homotetramerization; butyrate catabolic process; cellular lipid metabolic process; response to starvation; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation; fatty acid metabolic process
ACADSBcellular nitrogen compound metabolic process; lipid metabolic process; fatty acid metabolic process; acyl-CoA metabolic process; branched chain family amino acid catabolic process; small molecule metabolic process
ACADVLfatty acid beta-oxidation; temperature homeostasis; regulation of cholesterol metabolic process; negative regulation of fatty acid oxidation; negative regulation of fatty acid biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; very long-chain fatty acid catabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; endoplasmic reticulum unfolded protein response; energy derivation by oxidation of organic compounds; activation of signaling protein activity involved in unfolded protein response; fatty acid metabolic process
ACAP1lipid metabolic process; protein transport; regulation of ARF GTPase activity; intracellular signal transduction
ACAP3filopodium assembly; regulation of ARF GTPase activity; signal transduction
ACAT2lipid metabolic process
ACBD4-
ACBD5transport
ACBD6-
ACCSbiosynthetic process
ACEregulation of blood pressure; heart contraction; positive regulation of neurogenesis; positive regulation of inflammatory response; arachidonic acid secretion; peptide catabolic process; positive regulation of apoptotic process; eating behavior; hormone catabolic process; regulation of vasodilation; mononuclear cell proliferation; response to lipopolysaccharide; response to nutrient levels; sensory perception of pain; regulation of vasoconstriction; regulation of smooth muscle cell migration; proteolysis; regulation of systemic arterial blood pressure by renin-angiotensin; neutrophil mediated immunity; regulation of renal output by angiotensin; angiotensin catabolic process in blood; blood vessel remodeling; kidney development; response to hypoxia; hemopoietic stem cell differentiation
ACE2regulation of cytokine production; angiotensin catabolic process in blood; angiotensin-mediated drinking behavior; regulation of systemic arterial blood pressure by renin-angiotensin; proteolysis; response to virus; regulation of vasoconstriction; receptor biosynthetic process; regulation of cell proliferation; regulation of vasodilation; interspecies interaction between organisms; entry of virus into host cell; virion attachment, binding of host cell surface receptor; regulation of inflammatory response; positive regulation of reactive oxygen species metabolic process
ACER1ceramide catabolic process; small molecule metabolic process; sphingolipid biosynthetic process; sphingolipid metabolic process; regulation of lipid metabolic process
ACER2negative regulation of protein glycosylation in Golgi; sphingolipid biosynthetic process; response to retinoic acid; negative regulation of cell adhesion mediated by integrin; small molecule metabolic process; positive regulation of cell proliferation; ceramide metabolic process; sphingosine biosynthetic process; negative regulation of cell-matrix adhesion; lipid metabolic process; sphingolipid metabolic process
ACIN1positive regulation of monocyte differentiation; apoptotic chromosome condensation; erythrocyte differentiation; cellular component disassembly involved in apoptosis; apoptotic process; ATP catabolic process
ACKR2-
ACLYcellular carbohydrate metabolic process; small molecule metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; positive regulation of cellular metabolic process; triglyceride biosynthetic process; lipid biosynthetic process; ATP catabolic process; energy reserve metabolic process; citrate metabolic process; coenzyme A metabolic process
ACMSDsmall molecule metabolic process; tryptophan catabolic process; cellular nitrogen compound metabolic process; quinolinate metabolic process
ACO1response to iron(II) ion; intestinal absorption; regulation of gene expression; post-embryonic development; metabolic process; regulation of translation; citrate metabolic process; cellular iron ion homeostasis; tricarboxylic acid cycle
ACO2citrate metabolic process; tricarboxylic acid cycle; generation of precursor metabolites and energy; isocitrate metabolic process; small molecule metabolic process
ACOT11intracellular signal transduction; response to cold; response to temperature stimulus; fatty acid metabolic process
ACOT12acyl-CoA metabolic process; fatty acid metabolic process; lipid metabolic process; acetyl-CoA metabolic process
ACOT13protein homotetramerization
ACOT7lipid metabolic process
ACOT9acyl-CoA metabolic process
ACOX2fatty acid metabolic process; bile acid biosynthetic process; bile acid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; cellular lipid metabolic process; small molecule metabolic process
ACOX3small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid metabolic process
ACP2skeletal system development; lysosome organization; response to organic substance; dephosphorylation; autophagic cell death
ACPP-
ACPT-
ACRresponse to steroid hormone stimulus; response to biotic stimulus; penetration of zona pellucida; acrosome reaction; single fertilization; activation of adenylate cyclase activity; proteolysis; acrosome matrix dispersal
ACRBP-
ACRC-
ACRV1multicellular organismal development
ACSBG1myelination; lipid metabolic process; response to glucocorticoid stimulus; very long-chain fatty acid metabolic process; long-chain fatty acid metabolic process; ovarian follicle atresia
ACSBG2multicellular organismal development; cell differentiation; spermatogenesis; lipid metabolic process; fatty acid metabolic process
ACSF2lipid metabolic process; fatty acid metabolic process
ACSF3fatty acid biosynthetic process; lipid metabolic process; fatty acid metabolic process; malonate catabolic process
ACSL1fatty acid metabolic process; triglyceride biosynthetic process; long-chain fatty-acyl-CoA biosynthetic process; cellular lipid metabolic process; small molecule metabolic process; regulation of fatty acid oxidation
ACSL4positive regulation of cell growth; response to interleukin-15; dendritic spine development; embryonic process involved in female pregnancy; small molecule metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; response to nutrient; fatty acid metabolic process; lipid metabolic process
ACSL5cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; cellular response to insulin stimulus; triglyceride biosynthetic process; response to sucrose stimulus; fatty acid transport; positive regulation of triglyceride biosynthetic process; positive regulation of plasma membrane long-chain fatty acid transport; response to glucose stimulus; small molecule metabolic process; response to cholesterol; response to nutrient; fatty acid metabolic process
ACSL6acyl-CoA metabolic process; small molecule metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; neuroblast proliferation; fatty acid metabolic process
ACSM3lipid metabolic process; regulation of blood pressure; fatty acid biosynthetic process
ACSM6lipid metabolic process; fatty acid metabolic process
ACSS1propionate biosynthetic process; acetate biosynthetic process; xenobiotic metabolic process; acetyl-CoA biosynthetic process; ethanol oxidation; small molecule metabolic process
ACSS2small molecule metabolic process; lipid biosynthetic process; xenobiotic metabolic process; acetyl-CoA biosynthetic process; ethanol oxidation
ACSS3-
ACTA1muscle contraction; response to mechanical stimulus; response to extracellular stimulus; response to lithium ion; cell growth; muscle filament sliding; skeletal muscle thin filament assembly; skeletal muscle fiber adaptation; response to steroid hormone stimulus; skeletal muscle fiber development
ACTA2vascular smooth muscle contraction; glomerular mesangial cell development; response to virus; muscle contraction; regulation of blood pressure
ACTG2muscle contraction
ACTL6Aregulation of transcription from RNA polymerase II promoter; chromatin remodeling; DNA recombination; DNA repair; neural retina development; signal transduction; nervous system development; regulation of growth; histone H4 acetylation; histone H2A acetylation
ACTL6Bnervous system development; chromatin organization; chromatin remodeling; regulation of transcription from RNA polymerase II promoter
ACTL7A-
ACTL7B-
ACTL8-
ACTL9-
ACTN1platelet degranulation; blood coagulation; platelet activation; regulation of apoptotic process; focal adhesion assembly; actin filament bundle assembly; negative regulation of cellular component movement; cell junction assembly
ACTN2protein homotetramerization; focal adhesion assembly; regulation of apoptotic process; platelet activation; muscle filament sliding; microspike assembly; blood coagulation; synaptic transmission; cell adhesion; platelet degranulation
ACTR10microtubule-based movement
ACTR1Avesicle-mediated transport; G2/M transition of mitotic cell cycle; mitotic cell cycle
ACTR1B-
ACTR2cellular component movement
ACTRT1-
ACTRT2-
ACTRT3-
ACVR1cellular response to glucocorticoid stimulus; heart development; embryo development; negative regulation of signal transduction; regulation of ossification; positive regulation of bone mineralization; BMP signaling pathway; negative regulation of activin receptor signaling pathway; negative regulation of apoptotic process; positive regulation of osteoblast differentiation; positive regulation of transcription, DNA-dependent; regulation of skeletal muscle tissue development; smooth muscle cell differentiation; pharyngeal system development; patterning of blood vessels; determination of left/right symmetry; mesoderm development; G1/S transition of mitotic cell cycle; urogenital system development; in utero embryonic development; gastrulation with mouth forming second; mesoderm formation; neural crest cell migration; acute inflammatory response; protein phosphorylation; transmembrane receptor protein serine/threonine kinase signaling pathway; transforming growth factor beta receptor signaling pathway; germ cell
ACVR1Bprotein autophosphorylation; positive regulation of erythrocyte differentiation; positive regulation of activin receptor signaling pathway; activin receptor signaling pathway; negative regulation of cell growth; induction of apoptosis; peptidyl-threonine phosphorylation; signal transduction; protein phosphorylation; regulation of transcription, DNA-dependent; G1/S transition of mitotic cell cycle; transmembrane receptor protein serine/threonine kinase signaling pathway
ACVR2Aregulation of BMP signaling pathway; activin receptor signaling pathway; positive regulation of activin receptor signaling pathway; sperm ejaculation; penile erection; positive regulation of erythrocyte differentiation; positive regulation of osteoblast differentiation; positive regulation of follicle-stimulating hormone secretion; embryonic skeletal system development; regulation of nitric-oxide synthase activity; anterior/posterior pattern specification; Sertoli cell proliferation; positive regulation of bone mineralization; response to organic substance; BMP signaling pathway; mesoderm development; determination of left/right symmetry; spermatogenesis; transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of protein phosphorylation; gastrulation with mouth forming second
ACVR2Binsulin secretion; lung development; positive regulation of bone mineralization; BMP signaling pathway; pancreas development; activation of protein kinase activity; positive regulation of activin receptor signaling pathway; organ growth; odontogenesis of dentin-containing tooth; positive regulation of osteoblast differentiation; embryonic foregut morphogenesis; skeletal system morphogenesis; palate development; post-embryonic development; gastrulation with mouth forming second; kidney development; regulation of transcription, DNA-dependent; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; determination of left/right symmetry; pattern specification process; mesoderm development; heart development; response to glucose stimulus; anterior/posterior pattern specification
ACVRL1blood circulation; regulation of blood pressure; negative regulation of cell proliferation; negative regulation of focal adhesion assembly; negative regulation of endothelial cell migration; negative regulation of cell growth; negative regulation of cell migration; positive regulation of BMP signaling pathway; wound healing, spreading of epidermal cells; regulation of blood vessel endothelial cell migration; negative regulation of endothelial cell differentiation; positive regulation of endothelial cell differentiation; positive regulation of transcription, DNA-dependent; protein heterooligomerization; protein phosphorylation; transmembrane receptor protein serine/threonine kinase signaling pathway; signal transduction; negative regulation of cell adhesion; regulation of transcription, DNA-dependent; regulation of DNA replication; blood vessel endothelial cell proliferation involved in sprouting angiogenesis; blood vessel maturation; positive regulation of endothelial cell proliferation; negative regulation o
ACY1proteolysis; metabolic process; cellular amino acid metabolic process
ACY3metabolic process; interspecies interaction between organisms
ADAD1cell differentiation; spermatid development; spermatogenesis; multicellular organismal development; RNA processing
ADAD2RNA processing
ADALnucleotide metabolic process; inosine biosynthetic process; hypoxanthine salvage; purine ribonucleoside monophosphate biosynthetic process; adenosine catabolic process
ADAM10in utero embryonic development; protein phosphorylation; proteolysis; membrane protein ectodomain proteolysis; negative regulation of cell adhesion; epidermal growth factor receptor signaling pathway; Notch signaling pathway; integrin-mediated signaling pathway; cell-cell signaling; positive regulation of cell proliferation; positive regulation of T cell chemotaxis; positive regulation of cell growth; positive regulation of cell migration; response to tumor necrosis factor; monocyte activation; PMA-inducible membrane protein ectodomain proteolysis; constitutive protein ectodomain proteolysis; Notch receptor processing
ADAM11proteolysis; integrin-mediated signaling pathway
ADAM12myoblast fusion; epidermal growth factor receptor signaling pathway; cell adhesion; proteolysis
ADAM15cardiac epithelial to mesenchymal transition; angiogenesis; proteolysis; cell adhesion; cell-matrix adhesion; collagen catabolic process; tissue regeneration
ADAM17T cell differentiation in thymus; regulation of mast cell apoptosis; positive regulation of chemokine production; negative regulation of interleukin-8 production; response to lipopolysaccharide; positive regulation of cyclin-dependent protein kinase activity involved in G1/S; membrane protein intracellular domain proteolysis; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell migration; PMA-inducible membrane protein ectodomain proteolysis; positive regulation of cell growth; cell adhesion mediated by integrin; wound healing, spreading of epidermal cells; epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; response to drug; positive regulation of epidermal growth factor-activated receptor activity; nerve growth factor receptor signaling pathway; spleen development; cell motility; positive regulation of cellular component movement; response to high density lipoprotein particle stimulus; JAK-STAT
ADAM18cell differentiation; proteolysis; spermatogenesis; multicellular organismal development
ADAM19proteolysis
ADAM2proteolysis; cell adhesion; fusion of sperm to egg plasma membrane; visual learning; adult behavior
ADAM20single fertilization; proteolysis
ADAM23central nervous system development; cell adhesion; proteolysis
ADAM29proteolysis; spermatogenesis
ADAM30proteolysis
ADAM33proteolysis; integrin-mediated signaling pathway
ADAM7proteolysis
ADAMDEC1proteolysis; immune response; negative regulation of cell adhesion
ADAMTS1kidney development; ovulation from ovarian follicle; heart trabecula formation; negative regulation of cell proliferation; integrin-mediated signaling pathway; proteolysis
ADAMTS10proteolysis; integrin-mediated signaling pathway
ADAMTS12proteolysis
ADAMTS14proteolysis; collagen catabolic process
ADAMTS15proteolysis
ADAMTS16proteolysis
ADAMTS17proteolysis
ADAMTS18proteolysis
ADAMTS19proteolysis
ADAMTS2skin development; collagen catabolic process; lung development; collagen fibril organization; proteolysis; spermatogenesis; metabolic process; protein processing
ADAMTS4proteolysis; skeletal system development
ADAMTS5proteolysis
ADAMTS6proteolysis
ADAMTS8negative regulation of cell proliferation; proteolysis
ADAMTS9positive regulation of melanocyte differentiation; multicellular organismal development; glycoprotein catabolic process; regulation of developmental pigmentation; proteolysis
ADAMTSL1-
ADAMTSL2negative regulation of transforming growth factor beta receptor signaling pathway
ADAMTSL3-
ADAMTSL4extracellular matrix organization; positive regulation of apoptotic process
ADAP2heart development; positive regulation of GTPase activity; regulation of ARF GTPase activity
ADARgene expression; type I interferon-mediated signaling pathway; negative regulation of apoptotic process; gene silencing by RNA; cytokine-mediated signaling pathway; mRNA modification; base conversion or substitution editing; mRNA processing; adenosine to inosine editing
ADARB1base conversion or substitution editing; mRNA modification; gene expression; RNA processing; adenosine to inosine editing; mRNA processing
ADARB2RNA processing; mRNA processing
ADAT1RNA processing; tRNA processing
ADCK1-
ADCK2-
ADCK3cell death
ADCK4-
ADCY1long-term memory; cellular response to glucagon stimulus; transmembrane transport; nerve growth factor receptor signaling pathway; small molecule metabolic process; response to drug; intracellular signal transduction; activation of protein kinase A activity; response to lithium ion; fibroblast growth factor receptor signaling pathway; circadian rhythm; axonogenesis; activation of phospholipase C activity; energy reserve metabolic process; cAMP biosynthetic process; GTP catabolic process; water transport; signal transduction; epidermal growth factor receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; synaptic transmission
ADCY2activation of protein kinase A activity; transmembrane transport; nerve growth factor receptor signaling pathway; small molecule metabolic process; intracellular signal transduction; cellular response to glucagon stimulus; fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of phospholipase C activity; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; inhibition of adenylate cyclase activity by G-protein signaling pathway
ADCY3activation of phospholipase C activity; response to stimulus; synaptic transmission; sensory perception of smell; fibroblast growth factor receptor signaling pathway; activation of protein kinase A activity; intracellular signal transduction; small molecule metabolic process; nerve growth factor receptor signaling pathway; transmembrane transport; cellular response to glucagon stimulus; activation of adenylate cyclase activity by G-protein signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; energy reserve metabolic process; cAMP biosynthetic process; GTP catabolic process; water transport; female meiosis; signal transduction; epidermal growth factor receptor signaling pathway
ADCY4inhibition of adenylate cyclase activity by G-protein signaling pathway; fibroblast growth factor receptor signaling pathway; activation of protein kinase A activity; synaptic transmission; intracellular signal transduction; small molecule metabolic process; nerve growth factor receptor signaling pathway; transmembrane transport; epidermal growth factor receptor signaling pathway; signal transduction; cellular response to glucagon stimulus; water transport; GTP catabolic process; cAMP biosynthetic process; activation of phospholipase C activity; activation of adenylate cyclase activity by G-protein signaling pathway; energy reserve metabolic process; G-protein signaling, coupled to cAMP nucleotide second messenger
ADCY5cellular response to glucagon stimulus; transmembrane transport; nerve growth factor receptor signaling pathway; small molecule metabolic process; intracellular signal transduction; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of adenylate cyclase activity by G-protein signaling pathway; activation of phospholipase C activity; inhibition of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process
ADCY6transmembrane transport; nerve growth factor receptor signaling pathway; cellular response to glucagon stimulus; small molecule metabolic process; intracellular signal transduction; activation of protein kinase A activity; fibroblast growth factor receptor signaling pathway; synaptic transmission; activation of phospholipase C activity; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; inhibition of adenylate cyclase activity by G-protein signaling pathway
ADCY7fibroblast growth factor receptor signaling pathway; synaptic transmission; positive regulation of cAMP biosynthetic process; activation of protein kinase A activity; intracellular signal transduction; small molecule metabolic process; nerve growth factor receptor signaling pathway; transmembrane transport; cellular response to ethanol; cellular response to glucagon stimulus; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; epidermal growth factor receptor signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; activation of phospholipase C activity
ADCY8transmembrane transport; synaptic transmission; learning or memory; fibroblast growth factor receptor signaling pathway; cellular response to glucagon stimulus; cAMP-mediated signaling; activation of protein kinase A activity; intracellular signal transduction; small molecule metabolic process; nerve growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process; activation of phospholipase C activity
ADCY9activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; activation of protein kinase A activity; intracellular signal transduction; small molecule metabolic process; nerve growth factor receptor signaling pathway; transmembrane transport; cellular response to glucagon stimulus; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; signal transduction; water transport; GTP catabolic process; cAMP biosynthetic process; energy reserve metabolic process
ADCYAP1negative regulation of cell cycle; nerve growth factor receptor signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; female pregnancy; cell-cell signaling; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; activation of adenylate cyclase activity
ADCYAP1R1cell differentiation; positive regulation of inositol phosphate biosynthetic process; negative regulation of cell death; nerve growth factor receptor signaling pathway; development of primary female sexual characteristics; response to ethanol; response to drug; multicellular organismal response to stress; response to estradiol stimulus; positive regulation of cAMP biosynthetic process; cAMP-mediated signaling; positive regulation of calcium ion transport into cytosol; spermatogenesis; multicellular organismal development; activation of phospholipase C activity; activation of adenylate cyclase activity; transmembrane receptor protein tyrosine kinase signaling pathway; cell surface receptor signaling pathway
ADD1endoplasmic reticulum unfolded protein response; actin filament bundle assembly; barbed-end actin filament capping; positive regulation of protein binding; actin cytoskeleton organization; cellular component disassembly involved in apoptosis; apoptotic process; activation of signaling protein activity involved in unfolded protein response
ADD2ion transport; actin cytoskeleton organization; hemopoiesis; positive regulation of protein binding; barbed-end actin filament capping; actin filament bundle assembly
ADD3response to drug
ADGRA2regulation of chemotaxis; endothelial cell migration; regulation of angiogenesis; central nervous system development; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; sprouting angiogenesis
ADGRA3G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRB2G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; negative regulation of angiogenesis
ADGRB3G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; negative regulation of angiogenesis
ADGRD1G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRE1G-protein coupled receptor signaling pathway; cell adhesion; neuropeptide signaling pathway
ADGRE5cellular component movement; inflammatory response; immune response; cell adhesion; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; cell-cell signaling
ADGRF1neuropeptide signaling pathway; G-protein coupled receptor signaling pathway
ADGRF2G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRF4G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRG1brain development; cell-cell signaling; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; cell adhesion
ADGRG2neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; spermatogenesis
ADGRG3neuropeptide signaling pathway
ADGRG4G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRG5G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRG7neuropeptide signaling pathway; G-protein coupled receptor signaling pathway
ADGRL1neuropeptide signaling pathway; brain development; G-protein coupled receptor signaling pathway
ADGRL2G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADGRL4G-protein coupled receptor signaling pathway; neuropeptide signaling pathway
ADH6response to ethanol; small molecule metabolic process; xenobiotic metabolic process; ethanol oxidation
ADH7oxidation-reduction process; retinoid metabolic process; ethanol oxidation; xenobiotic metabolic process; response to bacterium; negative regulation of signal transduction; fatty acid omega-oxidation; small molecule metabolic process; response to ethanol
ADIPOR2fatty acid oxidation; hormone-mediated signaling pathway; lipid metabolic process
ADNPneuroprotection; nitric oxide homeostasis; estrous cycle phase; positive regulation of synapse assembly; negative regulation of synaptic transmission; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of axon extension; response to carbohydrate stimulus; short-term memory; negative regulation of neuron apoptosis; activation of protein kinase activity; negative regulation of protein binding; cellular response to extracellular stimulus; positive regulation of cGMP biosynthetic process; positive regulation of neuron projection development; regulation of protein ADP-ribosylation; negative regulation of gene expression; response to inorganic substance
ADNP2neuron differentiation; positive regulation of cell growth; cellular response to retinoic acid; negative regulation of cell death; cellular response to oxidative stress
ADORA1negative regulation of glutamate secretion; negative regulation of blood pressure; positive regulation of epidermal growth factor-activated receptor activity; positive regulation of blood pressure; positive regulation of potassium ion transport; negative regulation of apoptotic process; negative regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of renal sodium excretion; positive regulation of protein dephosphorylation; positive regulation of nucleoside transport; negative regulation of synaptic transmission, GABAergic; negative regulation of neurotrophin production; negative regulation of heart contraction; negative regulation of vasodilation; negative regulation of hormone secretion; regulation of synaptic plasticity; cognition; detection of temperature stimulus involved in sensory perception of pain; negative regulation of lipid catabolic process; negative regulation of synaptic transmission, glutamatergic; negative regulation of cardiac muscle contraction; regulation of excitato
ADPGKglycolysis; carbohydrate metabolic process
ADPRHL2-
ADPRM-
ADRA1Acell-cell signaling; elevation of cytosolic calcium ion concentration; aging; intracellular protein kinase cascade; activation of phospholipase C activity; G-protein coupled receptor signaling pathway; signal transduction; response to stress; smooth muscle contraction; apoptotic process; response to hormone stimulus; positive regulation of protein kinase C signaling cascade; positive regulation of ERK1 and ERK2 cascade; positive regulation of cardiac muscle contraction; calcium ion transport into cytosol; positive regulation of vasoconstriction; positive regulation of action potential; response to drug; negative regulation of cell proliferation; negative regulation of Rho protein signal transduction; negative regulation of synaptic transmission, GABAergic
ADRA1BG-protein signaling, coupled to cAMP nucleotide second messenger; multicellular organismal development; cell-cell signaling; adult heart development; intracellular protein kinase cascade; blood vessel remodeling; response to amphetamine; vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure; positive regulation of heart rate by epinephrine-norepinephrine; positive regulation of the force of heart contraction by epinephrine-norepinephrine; G-protein coupled receptor signaling pathway; locomotory behavior; cell proliferation; visual learning; cell growth; organ growth; glucose homeostasis; response to morphine; negative regulation of glycogen catabolic process; positive regulation of glycogen catabolic process; behavioral response to cocaine
ADRA2Anegative regulation of norepinephrine secretion; intestinal absorption; negative regulation of lipid catabolic process; positive regulation of membrane protein ectodomain proteolysis; negative regulation of calcium ion transport via voltage-gated calcium channel activity; negative regulation of insulin secretion involved in cellular response to glucose stimulus; negative regulation of adrenergic receptor signaling pathway; inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway; activation of phospholipase C activity by adrenergic receptor signaling pathway; activation of MAPK activity by adrenergic receptor signaling pathway; positive regulation of wound healing; actin cytoskeleton organization; small molecule metabolic process; positive regulation of cell proliferation; blood coagulation; Rho protein signal transduction; Ras protein signal transduction; regulation of insulin secretion; negative regulation of insulin secretion; negative regulation of calcium ion-dependent exocytosis
ADRB1sensory perception of pain; positive regulation of heart rate by epinephrine-norepinephrine; diet induced thermogenesis; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; positive regulation of the force of heart contraction by norepinephrine; positive regulation of systemic arterial blood pressure; glycogen catabolic process; apoptotic process; activation of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity; Rho protein signal transduction; aging; memory; response to cold; positive regulation of cAMP biosynthetic process; heat generation; negative regulation of urine volume; negative regulation of multicellular organism growth; wound healing; fear response; negative regulation of smooth muscle contraction; positive regulation of saliva secretion; brown fat cell differentiation; positive regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of inhibitory postsynaptic memb
ADRB3diet induced thermogenesis; activation of adenylate cyclase activity; aging; response to cold; heat generation; negative regulation of multicellular organism growth; eating behavior; positive regulation of MAPK cascade; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; receptor-mediated endocytosis; energy reserve metabolic process; generation of precursor metabolites and energy; carbohydrate metabolic process; desensitization of G-protein coupled receptor protein signaling pathway by arrestin; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; brown fat cell differentiation
ADRBK1heart development; cardiac muscle contraction; nerve growth factor receptor signaling pathway; regulation of the force of heart contraction; desensitization of G-protein coupled receptor protein signaling pathway; negative regulation of the force of heart contraction by chemical signal; response to oxidative stress; signal transduction; epidermal growth factor receptor signaling pathway; activation of phospholipase C activity; G-protein coupled acetylcholine receptor signaling pathway; tachykinin receptor signaling pathway; aging; fibroblast growth factor receptor signaling pathway; response to organic cyclic compound; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; receptor internalization; positive regulation of catecholamine secretion; termination of G-protein coupled receptor signaling pathway; response to hydrogen peroxide; follicle-stimulating hormone signaling pathway; negative regulation of striated muscle contraction
ADRBK2protein phosphorylation; signal transduction; receptor internalization; termination of G-protein coupled receptor signaling pathway
ADRM1transcription elongation from RNA polymerase II promoter; positive regulation of endopeptidase activity; proteasome assembly
ADSLprotein tetramerization; nucleobase-containing small molecule metabolic process; small molecule metabolic process; purine ribonucleoside monophosphate biosynthetic process; aerobic respiration; response to nutrient; AMP biosynthetic process; purine nucleotide biosynthetic process; purine base metabolic process; response to hypoxia
ADTRP-
AEBP1regulation of transcription, DNA-dependent; muscle organ development; cell adhesion; proteolysis; skeletal system development
AENapoptotic process; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; response to DNA damage stimulus; response to ionizing radiation
AFAP1-
AFAP1L1-
AFAP1L2positive regulation of protein tyrosine kinase activity; positive regulation of transcription, DNA-dependent; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of interleukin-8 production; regulation of interleukin-6 production; regulation of mitotic cell cycle; inflammatory response
AFF1regulation of transcription, DNA-dependent
AFF2mRNA processing; brain development; regulation of RNA splicing; learning or memory
AFF3embryonic hindlimb morphogenesis; response to tumor necrosis factor; regulation of transcription, DNA-dependent
AFF4spermatid development; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
AFMvitamin transport
AFMIDsmall molecule metabolic process; tryptophan catabolic process; tryptophan catabolic process to kynurenine; cellular nitrogen compound metabolic process
AFPsexual reproduction; pancreas development; organ regeneration; progesterone metabolic process; SMAD protein signal transduction; response to organic substance; transport; liver development; ovulation from ovarian follicle
AFTPHprotein transport
AGAP2small GTPase mediated signal transduction; negative regulation of protein catabolic process; axon guidance; protein transport; negative regulation of neuron apoptosis; regulation of ARF GTPase activity
AGAP3signal transduction; small GTPase mediated signal transduction; regulation of ARF GTPase activity
AGBL2proteolysis
AGBL5protein deglutamylation; protein branching point deglutamylation; proteolysis
AGFG1regulation of ARF GTPase activity; cell differentiation; spermatogenesis; multicellular organismal development; transport; mRNA export from nucleus
AGGF1positive regulation of endothelial cell proliferation; vasculogenesis; RNA processing; cell adhesion; multicellular organismal development; positive regulation of angiogenesis
AGKceramide biosynthetic process; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; metabolic process
AGLglucose metabolic process; response to nutrient; response to hormone stimulus; small molecule metabolic process; response to glucocorticoid stimulus; glycogen catabolic process; glycogen biosynthetic process; carbohydrate metabolic process
AGMATcellular nitrogen compound metabolic process; small molecule metabolic process; agmatine biosynthetic process; polyamine metabolic process; putrescine biosynthetic process; spermidine biosynthetic process
AGMOmembrane lipid metabolic process; fatty acid biosynthetic process; ether lipid metabolic process
AGO2-
AGO4-
AGPAT3metabolic process; phospholipid biosynthetic process
AGR3-
AGRNpositive regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; plasma membrane organization; signal transduction; G-protein coupled acetylcholine receptor signaling pathway; clustering of voltage-gated sodium channels; synapse organization; multicellular organismal development; neurotransmitter receptor metabolic process; axon guidance; receptor clustering; cell differentiation; regulation of receptor activity; regulation of synaptic growth at neuromuscular junction; neuromuscular junction development; synapse assembly
AGRPneuropeptide signaling pathway; feeding behavior; adult feeding behavior; hormone-mediated signaling pathway; regulation of feeding behavior
AGTpositive regulation of endothelial cell migration; regulation of blood volume by renin-angiotensin; nitric oxide mediated signal transduction; activation of NF-kappaB-inducing kinase activity; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; ovarian follicle rupture; regulation of cell growth; blood vessel development; positive regulation of cytokine production; kidney development; blood vessel remodeling; angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure; renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure; cell-cell signaling; renin-angiotensin regulation of aldosterone production; regulation of renal output by angiotensin; regulation of blood vessel size by renin-angiotensin; angiotensin-mediated drinking behavior; positive regulation of extracellular matrix constituent secretion; cellular sodium ion homeostasis; indu
AGTPBP1neuromuscular process; eye photoreceptor cell differentiation; proteolysis; mitochondrion organization; cerebellar Purkinje cell layer development; cerebellar Purkinje cell differentiation; olfactory bulb development; C-terminal protein deglutamylation; protein side chain deglutamylation; neurotransmitter metabolic process; retina development in camera-type eye
AGTR1positive regulation of cellular protein metabolic process; G-protein coupled receptor signaling pathway; positive regulation of phospholipase A2 activity; positive regulation of NAD(P)H oxidase activity; low-density lipoprotein particle remodeling; regulation of renal sodium excretion; regulation of cell proliferation; regulation of vasodilation; regulation of inflammatory response; positive regulation of inflammatory response; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; cell chemotaxis; positive regulation of reactive oxygen species metabolic process; regulation of vasoconstriction; regulation of cell growth; kidney development; renin-angiotensin regulation of aldosterone production; regulation of blood vessel size by renin-angiotensin; regulation of systemic arterial blood pressure by renin-angiotensin; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; elevation
AGXTresponse to cAMP; response to glucocorticoid stimulus; oxalic acid secretion; glyoxylate metabolic process; small molecule metabolic process; L-alanine catabolic process; cellular nitrogen compound metabolic process; glycine biosynthetic process, by transamination of glyoxylate; glyoxylate catabolic process; pyruvate biosynthetic process; protein targeting to peroxisome
AGXT2glyoxylate metabolic process; nucleobase-containing small molecule metabolic process; pyrimidine nucleoside catabolic process; small molecule metabolic process; pyrimidine base metabolic process; cellular nitrogen compound metabolic process
AHCTF1nuclear pore complex assembly; mRNA transport; protein transport; cytokinesis; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle
AHCYxenobiotic metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; methylation; one-carbon metabolic process; sulfur amino acid metabolic process
AHCYL1regulation of anion transport; regulation of ion transmembrane transporter activity; regulation of mRNA 3'-end processing; positive regulation of sodium ion transport; one-carbon metabolic process; protein export from nucleus; mRNA polyadenylation
AHCYL2one-carbon metabolic process
AHDC1-
AHNAKnervous system development
AHRintracellular receptor mediated signaling pathway; embryonic hemopoiesis; response to estradiol stimulus; regulation of B cell proliferation; post-embryonic hemopoiesis; positive regulation of growth rate; camera-type eye development; T cell homeostasis; positive regulation of cell size; positive regulation of transcription, DNA-dependent; prostate gland development; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; negative regulation of vasoconstriction; blood vessel morphogenesis; spleen development; smooth muscle tissue development; regulation of blood vessel size; negative regulation of necrotic cell death; venous blood vessel development; kidney morphogenesis; common bile duct development; cellular response to glucocorticoid stimulus; glomerulus morphogenesis; blood vessel remodeling; regulation of gene expression; negative regulation of transcription from RNA polymerase II promoter; cell morphogenesis; ovarian follicle development; blood vessel development; patter
AHRRregulation of transcription, DNA-dependent
AHSA1positive regulation of ATPase activity; protein folding; response to stress
AHSA2response to stress
AHSPprotein stabilization; hemopoiesis; hemoglobin metabolic process; protein folding
AIFM1neuron apoptosis; cell redox homeostasis; activation of cysteine-type endopeptidase activity involved in apoptotic process; DNA fragmentation involved in apoptotic nuclear change; apoptosis in response to endoplasmic reticulum stress
AIFM2induction of apoptosis; apoptotic mitochondrial changes; chromosome condensation
AIG1-
AIM1-
AIM1L-
AIPxenobiotic metabolic process; signal transduction; regulation of protein kinase A signaling cascade; protein maturation by protein folding; negative regulation of cyclic-nucleotide phosphodiesterase activity; protein targeting to mitochondrion
AIPL1protein folding; retina homeostasis; response to stimulus; negative regulation of apoptotic process; regulation of cGMP metabolic process; protein farnesylation; phototransduction, visible light; visual perception
AIREimmune response; humoral immune response; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
AJUBAcell cycle; positive regulation of cellular biosynthetic process; cell adhesion; calcium-dependent cell-cell adhesion; lamellipodium assembly; regulation of cell migration; positive regulation of protein complex assembly; positive regulation of kinase activity; negative regulation of transcription from RNA polymerase II promoter; gene silencing by miRNA; wound healing, spreading of epidermal cells; regulation of GTPase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAP kinase activity; glycerophospholipid biosynthetic process; focal adhesion assembly; negative regulation of kinase activity; cellular protein localization
AK5ATP metabolic process; ADP biosynthetic process; dADP biosynthetic process; signal transduction; nucleotide biosynthetic process; pyrimidine ribonucleotide biosynthetic process; nucleobase-containing small molecule metabolic process; nucleobase-containing small molecule interconversion; small molecule metabolic process
AK7cell projection organization; nucleobase-containing compound metabolic process
AK9-
AKAP1cellular response to insulin stimulus; blood coagulation; cellular response to chemical stimulus; negative regulation of NFAT protein import into nucleus; negative regulation of protein dephosphorylation; negative regulation of cardiac muscle hypertrophy
AKAP10protein localization; signal transduction; blood coagulation; termination of G-protein coupled receptor signaling pathway
AKAP11intracellular protein kinase cascade; regulation of protein kinase A signaling cascade
AKAP12positive regulation of cAMP biosynthetic process; positive regulation of protein kinase A signaling cascade; G-protein coupled receptor signaling pathway; signal transduction; protein targeting
AKAP13small GTPase mediated signal transduction; apoptotic process; induction of apoptosis by extracellular signals; regulation of Rho protein signal transduction; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction
AKAP3cellular component movement; protein localization; acrosome reaction; transmembrane receptor protein serine/threonine kinase signaling pathway; single fertilization
AKAP4single fertilization; cellular component movement; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; sperm motility; protein localization; cell projection organization
AKAP5signal transduction; protein targeting; energy reserve metabolic process; synaptic transmission; positive regulation of protein kinase A signaling cascade; positive regulation of cAMP biosynthetic process; small molecule metabolic process; regulation of insulin secretion
AKAP6protein targeting; positive regulation of protein phosphatase type 2B activity; regulation of protein kinase A signaling cascade
AKAP7ion transport; protein localization; intracellular signal transduction; RNA metabolic process; regulation of protein kinase A signaling cascade
AKAP8mitosis; mitotic chromosome condensation; signal transduction
AKAP9transport; G2/M transition of mitotic cell cycle; mitotic cell cycle; signal transduction; synaptic transmission
AKNAregulation of transcription, DNA-dependent
AKNAD1-
AKR1A1glucose metabolic process; cellular aldehyde metabolic process; L-ascorbic acid biosynthetic process; D-glucuronate catabolic process; aldehyde catabolic process
AKR1D1bile acid biosynthetic process; cholesterol catabolic process; digestion; bile acid metabolic process; C21-steroid hormone metabolic process; androgen metabolic process; bile acid catabolic process; small molecule metabolic process; oxidation-reduction process
AKT3mitochondrial genome maintenance; protein phosphorylation; signal transduction
AKTIPpositive regulation of protein phosphorylation; apoptotic process; endosome to lysosome transport; endosome organization; lysosome organization; protein transport; early endosome to late endosome transport; positive regulation of protein binding
ALADporphyrin-containing compound metabolic process; heme biosynthetic process; small molecule metabolic process; protein homooligomerization
ALAS1tetrapyrrole biosynthetic process; cellular lipid metabolic process; small molecule metabolic process; heme biosynthetic process; biosynthetic process; porphyrin-containing compound metabolic process
ALAS2tetrapyrrole biosynthetic process; small molecule metabolic process; hemoglobin biosynthetic process; oxygen homeostasis; erythrocyte differentiation; biosynthetic process; cellular iron ion homeostasis; heme biosynthetic process; porphyrin-containing compound metabolic process; response to hypoxia
ALBresponse to mercury ion; positive regulation of circadian sleep/wake cycle, non-REM sleep; small molecule metabolic process; sodium-independent organic anion transport; negative regulation of programmed cell death; negative regulation of apoptotic process; lipoprotein metabolic process; platelet activation; hemolysis by symbiont of host erythrocytes; bile acid and bile salt transport; response to organic substance; cellular response to starvation; bile acid metabolic process; blood coagulation; response to nutrient; response to stress; transport; lipid metabolic process; platelet degranulation; maintenance of mitochondrion location; transmembrane transport; response to platinum ion
ALCAMcell adhesion; signal transduction; axon guidance; motor axon guidance
ALDH16A1-
ALDH18A1small molecule metabolic process; cellular nitrogen compound metabolic process; cellular amino acid biosynthetic process; proline biosynthetic process
ALDH1A1positive regulation of Ras GTPase activity; small molecule metabolic process; xenobiotic metabolic process; cellular aldehyde metabolic process; ethanol oxidation
ALDH1A2liver development; determination of bilateral symmetry; neuron differentiation; pituitary gland development; neural tube development; morphogenesis of embryonic epithelium; neural crest cell development; positive regulation of gene expression; proximal/distal pattern formation; anterior/posterior pattern specification; blood vessel development; negative regulation of cell proliferation; positive regulation of cell proliferation; midgut development; vitamin A metabolic process; heart morphogenesis; regulation of endothelial cell proliferation; kidney development; forebrain development; cellular response to retinoic acid; face development; embryonic digestive tract development; retinoic acid receptor signaling pathway; positive regulation of apoptotic process; 9-cis-retinoic acid biosynthetic process; retinal metabolic process; retinoic acid metabolic process; embryonic forelimb morphogenesis; response to cytokine stimulus; response to vitamin A; response to estradiol stimulus; embryonic camera-type eye develop
ALDH1B1carbohydrate metabolic process
ALDH1L1biosynthetic process; 10-formyltetrahydrofolate catabolic process
ALDH1L2biosynthetic process; 10-formyltetrahydrofolate catabolic process
ALDH2carbohydrate metabolic process; alcohol metabolic process; ethanol oxidation; xenobiotic metabolic process; synaptic transmission; neurotransmitter biosynthetic process; small molecule metabolic process
ALDH3A2oxidation-reduction process; cellular aldehyde metabolic process
ALDH4A1proline metabolic process; cellular nitrogen compound metabolic process; proline biosynthetic process; proline catabolic process; small molecule metabolic process
ALDH6A1valine metabolic process; branched chain family amino acid catabolic process; thymine metabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process
ALDH8A1retinoic acid metabolic process; 9-cis-retinoic acid biosynthetic process; retinal metabolic process
ALDH9A1kidney development; liver development; cellular aldehyde metabolic process; cellular nitrogen compound metabolic process; neurotransmitter biosynthetic process; hormone metabolic process; small molecule metabolic process; carnitine biosynthetic process; oxidation-reduction process
ALDOAglucose metabolic process; small molecule metabolic process; gluconeogenesis; glycolysis; ATP biosynthetic process; striated muscle contraction; actin filament organization; blood coagulation; fructose metabolic process; carbohydrate metabolic process; platelet degranulation; platelet activation; fructose 1,6-bisphosphate metabolic process; regulation of cell shape; muscle cell homeostasis; protein homotetramerization
ALDOBfructose 1,6-bisphosphate metabolic process; gluconeogenesis; glycolysis; glucose metabolic process; fructose catabolic process; fructose metabolic process; carbohydrate metabolic process; NADH oxidation; positive regulation of ATPase activity; small molecule metabolic process; vacuolar proton-transporting V-type ATPase complex assembly
ALDOCgluconeogenesis; response to hypoxia; carbohydrate metabolic process; fructose metabolic process; protein heterotetramerization; protein homotetramerization; organ regeneration; fructose 1,6-bisphosphate metabolic process; glucose metabolic process; response to organic cyclic compound; glycolysis; apoptotic process; response to organic nitrogen; aging; small molecule metabolic process
ALG11dolichol-linked oligosaccharide biosynthetic process; biosynthetic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process
ALG2response to calcium ion; dolichol-linked oligosaccharide biosynthetic process; biosynthetic process; protein N-linked glycosylation via asparagine; cellular protein metabolic process; protein glycosylation in endoplasmic reticulum; post-translational protein modification
ALG9protein N-linked glycosylation via asparagine; dolichol-linked oligosaccharide biosynthetic process; cellular protein metabolic process; GPI anchor biosynthetic process; post-translational protein modification
ALKtransmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of NF-kappaB transcription factor activity; neuron development; protein autophosphorylation; regulation of apoptotic process; NIK/NF-kappaB cascade; phosphorylation; cell proliferation; signal transduction; activation of MAPK activity
ALKBH2oxidative DNA demethylation; DNA repair; DNA demethylation; oxidative demethylation; DNA dealkylation involved in DNA repair
ALKBH7-
ALKBH8response to DNA damage stimulus; tRNA methylation
ALMS1sensory perception of sound; epithelial cell proliferation; G2/M transition of mitotic cell cycle; mitotic cell cycle; lipid metabolic process; triglyceride metabolic process; apoptotic process; developmental growth; retinal rod cell development; regulation of fat cell differentiation; cholesterol homeostasis; glucose homeostasis; cilium assembly; calcium-mediated signaling; spermatid development
ALOX12negative regulation of cell killing; positive regulation of cell growth; positive regulation of mitochondrial depolarization; fatty acid oxidation; positive regulation of cell killing; superoxide anion generation; positive regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of endothelial cell differentiation; positive regulation of cell adhesion; reactive oxygen species metabolic process; positive regulation of gene expression; positive regulation of endothelial cell migration; positive regulation of cell proliferation; cellular component movement; anti-apoptosis; leukotriene biosynthetic process
ALOX12Bleukotriene biosynthetic process; epidermis development; lipid metabolic process
ALOXE3leukotriene biosynthetic process
ALPIphosphorylation
ALPK1protein phosphorylation
ALPK2protein phosphorylation
ALPK3heart development; multicellular organismal development; protein phosphorylation
ALPLresponse to lipopolysaccharide; response to vitamin D; response to antibiotic; response to glucocorticoid stimulus; cellular response to organic cyclic compound; cementum mineralization; skeletal system development; biomineral tissue development
ALS2positive regulation of Rac GTPase activity; in utero embryonic development; endosome organization; axonogenesis; cell death; positive regulation of Rac protein signal transduction; regulation of Rho protein signal transduction; positive regulation of protein kinase activity; neuron projection morphogenesis; regulation of endosome size; positive regulation of protein serine/threonine kinase activity
ALS2CLendosome organization; regulation of Rho protein signal transduction
ALS2CR11-
ALX1negative regulation of transcription from RNA polymerase II promoter; cartilage condensation; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; multicellular organismal development; brain development; positive regulation of transcription, DNA-dependent
ALX3multicellular organismal development
ALX4palate development; embryonic skeletal system morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of apoptotic process; embryonic digit morphogenesis; embryonic hindlimb morphogenesis; embryonic forelimb morphogenesis; limb morphogenesis; anterior/posterior pattern specification; post-embryonic development; skeletal system development; digestive tract development; hair follicle development; muscle organ development; pattern specification process
AMBNcell adhesion; cell proliferation; bone mineralization; odontogenesis of dentin-containing tooth
AMBRA1multicellular organismal development; nervous system development; autophagy; cell differentiation
AMDHD2N-acetylglucosamine metabolic process; carbohydrate metabolic process
AMER1-
AMER3-
AMHcell-cell signaling; positive regulation of NF-kappaB transcription factor activity; response to drug; cell differentiation; response to organic cyclic compound; positive regulation of gene expression; aging; sex determination; gonadal mesoderm development; Mullerian duct regression; urogenital system development; preantral ovarian follicle growth; sex differentiation
AMHR2Mullerian duct regression; signal transduction; transforming growth factor beta receptor signaling pathway; sex differentiation
AMIGO1myelination; positive regulation of axonogenesis; cell differentiation; axonal fasciculation; nervous system development; multicellular organismal development; heterophilic cell-cell adhesion; homophilic cell adhesion; cell adhesion
AMIGO2heterophilic cell-cell adhesion; homophilic cell adhesion; negative regulation of programmed cell death; anti-apoptosis; cell adhesion
AMOThippo signaling cascade; negative regulation of vascular permeability; positive regulation of blood vessel endothelial cell migration; cell migration involved in gastrulation; positive regulation of cell size; positive regulation of embryonic development; positive regulation of stress fiber assembly; negative regulation of angiogenesis; in utero embryonic development; gastrulation with mouth forming second; vasculogenesis; chemotaxis; cell-cell junction assembly; actin cytoskeleton organization; regulation of cell migration; cellular protein localization
AMOTL2-
AMPD1nucleotide metabolic process; nucleobase-containing small molecule metabolic process; small molecule metabolic process; purine-containing compound salvage; IMP biosynthetic process; purine base metabolic process
AMPD2purine base metabolic process; purine nucleotide metabolic process; IMP biosynthetic process; purine-containing compound salvage; small molecule metabolic process; nucleobase-containing small molecule metabolic process
AMPD3purine-containing compound salvage; small molecule metabolic process; nucleobase-containing small molecule metabolic process; nucleotide metabolic process; IMP biosynthetic process; purine base metabolic process; AMP catabolic process
AMPHendocytosis; synaptic transmission; learning; positive regulation of GTPase activity; positive regulation of endocytosis; synaptic vesicle endocytosis
AMTglycine catabolic process
AMZ1proteolysis
ANAPC11regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell cycle checkpoint; mitotic cell cycle; mitosis; mitotic cell cycle spindle assembly checkpoint; protein ubiquitination; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination
ANAPC5negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; cell division; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; mitotic cell cycle spindle assembly checkpoint; ubiquitin-dependent protein catabolic process; mitotic cell cycle; mitotic anaphase; G2/M transition of mitotic cell cycle; cell cycle checkpoint
ANGEL1-
ANGEL2-
ANGPT1regulation of satellite cell proliferation; positive regulation of endothelial cell migration; blood coagulation; multicellular organismal development; activation of transmembrane receptor protein tyrosine kinase activity; signal transduction; negative regulation of cell adhesion; anti-apoptosis; positive regulation of receptor internalization; sprouting angiogenesis; regulation of endothelial cell proliferation; negative regulation of endothelial cell apoptosis; negative regulation of vascular permeability; negative regulation of apoptotic process; protein localization at cell surface; positive regulation of protein ubiquitination; heparin biosynthetic process; cell differentiation; Tie receptor signaling pathway; positive regulation of peptidyl-tyrosine phosphorylation; leukocyte migration; positive chemotaxis; positive regulation of protein kinase B signaling cascade; positive regulation of ERK1 and ERK2 cascade; positive regulation of blood vessel endothelial cell migration
ANGPT2response to activity; response to organic cyclic compound; negative regulation of angiogenesis; cell differentiation; organ regeneration; negative regulation of blood vessel endothelial cell migration; positive regulation of angiogenesis; Tie receptor signaling pathway; leukocyte migration; negative regulation of positive chemotaxis; maternal process involved in female pregnancy; negative regulation of cell-substrate adhesion; response to glucose stimulus; response to mechanical stimulus; response to radiation; blood coagulation; germ cell development; multicellular organismal development; signal transduction; response to hypoxia
ANGPTL1transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction
ANGPTL2signal transduction; multicellular organismal development
ANGPTL3triglyceride homeostasis; glycerol metabolic process; phospholipid homeostasis; acylglycerol homeostasis; lipid homeostasis; negative regulation of lipoprotein lipase activity; positive regulation of lipid catabolic process; artery morphogenesis; positive regulation of angiogenesis; negative regulation of catalytic activity; cholesterol homeostasis; positive regulation of cell migration; lipid storage; negative regulation of phospholipase activity; response to hormone stimulus; phospholipid catabolic process; cholesterol metabolic process; integrin-mediated signaling pathway; signal transduction; cell-matrix adhesion; phospholipid metabolic process; fatty acid metabolic process
ANGPTL5signal transduction
ANK1exocytosis; cytoskeleton organization; signal transduction; axon guidance; maintenance of epithelial cell apical/basal polarity
ANK2signal transduction; axon guidance
ANK3signal transduction; establishment of protein localization
ANKAR-
ANKEF1-
ANKFN1-
ANKFY1-
ANKHskeletal system development; transport; locomotory behavior; regulation of bone mineralization; inorganic diphosphate transport
ANKLE2-
ANKMY1-
ANKMY2-
ANKRD11head morphogenesis; skeletal system morphogenesis; multicellular organism growth; tissue homeostasis; bone development; in utero embryonic development
ANKRD12-
ANKRD13B-
ANKRD13D-
ANKRD16-
ANKRD17interspecies interaction between organisms
ANKRD2muscle organ development; muscle contraction
ANKRD22-
ANKRD26-
ANKRD27early endosome to late endosome transport
ANKRD34A-
ANKRD34B-
ANKRD35-
ANKRD44-
ANKRD46-
ANKRD50-
ANKRD53-
ANKRD55-
ANKRD7male gonad development
ANKRD9-
ANKS1Aephrin receptor signaling pathway; substrate-dependent cell migration; neuron remodeling
ANKS3-
ANKS4B-
ANKS6-
ANKZF1-
ANLNregulation of exit from mitosis; cytokinesis; septin ring assembly; cell cycle; mitosis
ANO10ion transport; cell death
ANO3ion transport
ANO4ion transport
ANO5ion transport
ANO6activation of blood coagulation via clotting cascade; ion transport; phosphatidylserine exposure on blood platelet
ANO7ion transport
ANO9ion transport
ANP32Enegative regulation of catalytic activity
ANPEPinterspecies interaction between organisms; negative regulation of renal sodium excretion; cell differentiation; metabolic process; multicellular organismal development; cellular aromatic compound metabolic process; proteolysis; angiogenesis
ANTXR1actin cytoskeleton reorganization; substrate adhesion-dependent cell spreading
ANXA10-
ANXA4anti-apoptosis; signal transduction; negative regulation of coagulation
ANXA7hemostasis; cell proliferation; regulation of cell shape; response to salt stress; cellular water homeostasis; social behavior; cellular calcium ion homeostasis
ANXA9cell-cell adhesion
AOAHlipid metabolic process; inflammatory response; lipopolysaccharide metabolic process; negative regulation of inflammatory response
AOC1-
AOC2catecholamine metabolic process; visual perception; amine metabolic process
AOX1inflammatory response; reactive oxygen species metabolic process
AP1ARprotein transport
AP1B1intracellular protein transport; post-Golgi vesicle-mediated transport; endocytosis; viral reproduction; cellular membrane organization; regulation of defense response to virus by virus
AP1G1regulation of defense response to virus by virus; intracellular protein transport; post-Golgi vesicle-mediated transport; endocytosis; viral reproduction; cellular membrane organization
AP1M1cellular membrane organization; interspecies interaction between organisms; endosome to melanosome transport; melanosome organization; vesicle-mediated transport; regulation of defense response to virus by virus; viral reproduction; post-Golgi vesicle-mediated transport; intracellular protein transport
AP2M1synaptic transmission; regulation of defense response to virus by virus; nerve growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; vesicle-mediated transport; cellular membrane organization; viral reproduction; axon guidance; epidermal growth factor receptor signaling pathway; intracellular protein transport; transport
AP2S1protein transport; transport; intracellular protein transport; epidermal growth factor receptor signaling pathway; axon guidance; synaptic transmission; viral reproduction; vesicle-mediated transport; regulation of endocytosis; negative regulation of epidermal growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; clathrin coat assembly; regulation of defense response to virus by virus
AP3B1endocytosis; antigen processing and presentation; melanosome organization; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; positive regulation of NK T cell differentiation; intracellular protein transport; protein targeting to lysosome; blood coagulation
AP3M1protein targeting to lysosome; intracellular protein transport; vesicle-mediated transport
AP3M2vesicle-mediated transport; intracellular protein transport
AP3S1insulin receptor signaling pathway; vesicle-mediated transport; intracellular protein transport; transport
AP4B1vesicle-mediated transport; intracellular protein transport; transport
AP4E1vesicle-mediated transport; intracellular protein transport
AP4M1vesicle-mediated transport; intracellular protein transport
AP5M1vesicle-mediated transport; intracellular protein transport
APAF1regulation of apoptotic process; intrinsic apoptotic signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; induction of apoptosis by intracellular signals; nervous system development; defense response; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process
APBA1locomotory behavior; protein complex assembly; intracellular protein transport; cell adhesion; synaptic transmission; in utero embryonic development; nervous system development; axon cargo transport; regulation of gene expression; glutamate secretion; gamma-aminobutyric acid secretion; multicellular organism growth
APBA2nervous system development; protein transport
APBB1IPplatelet activation; blood coagulation; signal transduction
APBB2cell cycle arrest; negative regulation of cell growth; regulation of transcription, DNA-dependent; intracellular signal transduction; negative regulation of S phase of mitotic cell cycle
APBB3intracellular signal transduction
APCnegative regulation of epithelial cell proliferation involved in prostate gland development; regulation of microtubule-based process; tight junction assembly; regulation of osteoblast differentiation; skin development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of MAPK cascade; negative regulation of apoptotic process; positive regulation of apoptotic process; response to drug; negative regulation of odontogenesis; somatic stem cell maintenance; T cell differentiation in thymus; canonical Wnt receptor signaling pathway; retina development in camera-type eye; regulation of attachment of spindle microtubules to kinetochore; positive regulation of cell division; regulation of cell cycle; chromosome organization; regulation of nitrogen compound metabolic process; thymus development; muscle cell homeostasis; positive regulation of cell adhesion; negative regulation of cyclin-dependent protein kinase activity; positive regulation of protein catabolic process; regulation of
APC2negative regulation of canonical Wnt receptor signaling pathway; negative regulation of catenin import into nucleus; Wnt receptor signaling pathway
APCDD1hair follicle development; negative regulation of Wnt receptor signaling pathway
APCSprotein folding; chaperone-mediated protein complex assembly; acute-phase response
APEHproteolysis
APEX2cell cycle; DNA repair; DNA recombination
API5apoptotic process; anti-apoptosis
APLFsingle strand break repair; double-strand break repair; response to DNA damage stimulus
APLNRG-protein coupled receptor signaling pathway; regulation of body fluid levels
APLP1apoptotic process; negative regulation of cAMP biosynthetic process; forebrain development; cellular response to norepinephrine stimulus; extracellular matrix organization; organ morphogenesis; cell death; mRNA polyadenylation; regulation of translation; endocytosis; cell adhesion; inhibition of adenylate cyclase activity by G-protein signaling pathway; nervous system development
APMAP-
APOA1cholesterol homeostasis; blood vessel endothelial cell migration; reverse cholesterol transport; lipoprotein biosynthetic process; lipoprotein metabolic process; high-density lipoprotein particle remodeling; high-density lipoprotein particle clearance; cellular lipid metabolic process; small molecule metabolic process; negative regulation of interleukin-1 beta secretion; protein stabilization; positive regulation of hydrolase activity; negative regulation of hydrolase activity; positive regulation of transferase activity; transmembrane transport; cholesterol import; high-density lipoprotein particle assembly; regulation of protein phosphorylation; endothelial cell proliferation; platelet degranulation; negative regulation of cytokine secretion involved in immune response; lipid metabolic process; phospholipid metabolic process; phosphatidylcholine biosynthetic process; cholesterol biosynthetic process; G-protein coupled receptor signaling pathway; blood coagulation; steroid metabolic process; cholesterol meta
APOA4multicellular organismal lipid catabolic process; reverse cholesterol transport; hydrogen peroxide catabolic process; cholesterol homeostasis; phospholipid efflux; lipoprotein metabolic process; small molecule metabolic process; positive regulation of fatty acid biosynthetic process; phosphatidylcholine metabolic process; positive regulation of lipoprotein lipase activity; lipid homeostasis; protein-lipid complex assembly; negative regulation of plasma lipoprotein particle oxidation; innate immune response in mucosa; lipid metabolic process; transport; lipid transport; response to lipid hydroperoxide; leukocyte cell-cell adhesion; cholesterol metabolic process; positive regulation of cholesterol esterification; positive regulation of triglyceride catabolic process; removal of superoxide radicals; regulation of intestinal cholesterol absorption; regulation of cholesterol transport; cholesterol efflux; chylomicron remodeling; very-low-density lipoprotein particle remodeling; high-density lipoprotein particle re
APOBvery-low-density lipoprotein particle assembly; sperm motility; response to lipopolysaccharide; low-density lipoprotein particle remodeling; positive regulation of cholesterol storage; cholesterol transport; triglyceride catabolic process; lipid catabolic process; regulation of cholesterol biosynthetic process; low-density lipoprotein particle clearance; lipoprotein metabolic process; lipoprotein biosynthetic process; lipoprotein catabolic process; cholesterol homeostasis; lipoprotein transport; small molecule metabolic process; transport; positive regulation of lipid storage; positive regulation of macrophage derived foam cell differentiation; response to selenium ion; post-embryonic development; response to carbohydrate stimulus; response to virus; fertilization; cholesterol metabolic process; steroid metabolic process; blood coagulation; nervous system development; spermatogenesis; receptor-mediated endocytosis; in utero embryonic development; lipid metabolic process; triglyceride mobilization; leukocyte m
APOBEC2mRNA modification; mRNA processing; cytidine deamination; DNA demethylation
APOBEC3Gpositive regulation of defense response to virus by host; innate immune response; negative regulation of retroviral genome replication; negative regulation of viral reproduction; DNA cytosine deamination; negative regulation of viral genome replication; interspecies interaction between organisms; base conversion or substitution editing; response to virus; cytidine deamination; negative regulation of transposition; viral reproduction
APOC3Cdc42 protein signal transduction; cholesterol efflux; phospholipid efflux; high-density lipoprotein particle remodeling; very-low-density lipoprotein particle assembly; chylomicron remnant clearance; lipoprotein metabolic process; cholesterol homeostasis; reverse cholesterol transport; transport; small molecule metabolic process; negative regulation of fatty acid biosynthetic process; negative regulation of lipid metabolic process; triglyceride homeostasis; negative regulation of cholesterol import; negative regulation of lipoprotein lipase activity; negative regulation of lipid catabolic process; negative regulation of receptor-mediated endocytosis; negative regulation of low-density lipoprotein particle clearance; triglyceride catabolic process; lipid metabolic process; triglyceride metabolic process; triglyceride mobilization; lipid transport; G-protein coupled receptor signaling pathway; cholesterol metabolic process; negative regulation of triglyceride catabolic process; negative regulation of very-low-
APOL1lipid transport; steroid metabolic process; cholesterol metabolic process; cytolysis; killing of cells of other organism; lipoprotein metabolic process; innate immune response; chloride transport; transport
APOL3signal transduction; lipoprotein metabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; transport; inflammatory response; lipid transport
APOL5lipoprotein metabolic process; transport; lipid metabolic process; lipid transport
APOPT1positive regulation of smooth muscle cell apoptosis; induction of apoptosis by intracellular signals; positive regulation of release of cytochrome c from mitochondria; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
APPplatelet activation; extracellular matrix organization; forebrain development; neuron projection development; ionotropic glutamate receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; regulation of multicellular organism growth; innate immune response; negative regulation of neuron differentiation; positive regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; collateral sprouting in absence of injury; regulation of synapse structure and activity; neuromuscular process controlling balance; synaptic growth at neuromuscular junction; neuron apoptosis; smooth endoplasmic reticulum calcium ion homeostasis; regulation of gene expression; cell adhesion; dendrite development; suckling behavior; platelet degranulation; mRNA polyadenylation; regulation of translation; protein phosphorylation; cellular copper ion homeostasis; endocytosis; induction of apoptosis; regulation of epidermal growth factor-activated
APPBP2intracellular protein transport; intracellular transport
APPL1regulation of establishment of protein localization in plasma membrane; cell cycle; signal transduction; cell proliferation; insulin receptor signaling pathway; regulation of apoptotic process; regulation of glucose import; apoptotic process
APPL2cell proliferation; signal transduction; cell cycle
APRTgrooming behavior; nucleobase-containing small molecule metabolic process; small molecule metabolic process; purine-containing compound salvage; nucleoside metabolic process; adenine salvage; purine ribonucleoside salvage; purine base metabolic process; lactation
AQP1response to drug; negative regulation of apoptotic process; positive regulation of angiogenesis; positive regulation of saliva secretion; positive regulation of fibroblast proliferation; multicellular organismal water homeostasis; transmembrane transport; cellular response to hydrogen peroxide; cellular response to inorganic substance; cellular response to mechanical stimulus; cellular response to copper ion; cellular response to mercury ion; cellular response to retinoic acid; cellular response to cAMP; cellular response to hypoxia; potassium ion transport; cellular response to salt stress; cellular hyperosmotic response; cellular response to dexamethasone stimulus; cellular response to nitric oxide; potassium ion transmembrane transport; maintenance of symbiont-containing vacuole via substance secreted by host; carbon dioxide transmembrane transport; odontogenesis; renal water transport; cGMP biosynthetic process; water transport; cell volume homeostasis; carbon dioxide transport; ammonium transport; glycer
AQP11ion transport; protein homooligomerization; endosomal lumen acidification; urea transport; glycerol transport; water transport; kidney development
AQP5transmembrane transport; camera-type eye morphogenesis; saliva secretion; odontogenesis; pancreatic juice secretion; excretion; carbon dioxide transport; water transport
AQP8transmembrane transport; canalicular bile acid transport; water transport; transport; cellular response to cAMP
AQRnuclear mRNA splicing, via spliceosome; RNA splicing
ARnegative regulation of epithelial cell proliferation; male genitalia morphogenesis; organ formation; regulation of developmental growth; male sex differentiation; positive regulation of transcription from RNA polymerase III promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of integrin biosynthetic process; regulation of establishment of protein localization in plasma membrane; negative regulation of integrin biosynthetic process; regulation of catalytic activity; positive regulation of NF-kappaB transcription factor activity; activation of prostate induction by androgen receptor signaling pathway; morphogenesis of an epithelial fold; lateral sprouting involved in mammary gland duct morphogenesis; regulation of prostatic bud formation; prostate gland growth; prostate gland epithelium morphogenesis; epithelial cell differentiation involved in prostate gland development; tertiary branching involved in mammary g
ARAP1negative regulation of stress fiber assembly; actin filament reorganization involved in cell cycle; regulation of cellular component movement; regulation of ARF GTPase activity; regulation of cell shape; small GTPase mediated signal transduction; signal transduction; positive regulation of Cdc42 GTPase activity; regulation of small GTPase mediated signal transduction; positive regulation of filopodium assembly
ARAP2small GTPase mediated signal transduction; regulation of ARF GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction
ARAP3negative regulation of Rho protein signal transduction; positive regulation of Rho GTPase activity; negative regulation of Rac protein signal transduction; regulation of ARF GTPase activity; cytoskeleton organization; negative regulation of cell migration; vesicle-mediated transport; regulation of cell shape; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction
ARCanterior/posterior pattern specification; cell migration; endocytosis; cytoskeleton organization; multicellular organismal development; endoderm development; regulation of cell morphogenesis; regulation of neuronal synaptic plasticity; learning
ARCN1COPI coating of Golgi vesicle; vesicle-mediated transport; cellular membrane organization; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; transport
AREL1-
ARF1regulation of defense response to virus by virus; GTP catabolic process; cellular copper ion homeostasis; retrograde vesicle-mediated transport, Golgi to ER; post-Golgi vesicle-mediated transport; small GTPase mediated signal transduction; protein transport; viral reproduction; cellular membrane organization; vesicle-mediated transport; COPI coating of Golgi vesicle
ARFGAP1COPI coating of Golgi vesicle; regulation of ARF GTPase activity; endoplasmic reticulum unfolded protein response; vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; activation of signaling protein activity involved in unfolded protein response; protein transport; cellular membrane organization
ARFGAP2protein transport; vesicle-mediated transport; regulation of ARF GTPase activity
ARFGAP3vesicle-mediated transport; protein secretion; regulation of ARF GTPase activity; intracellular protein transport
ARFGEF2vesicle-mediated transport; regulation of ARF protein signal transduction; intracellular signal transduction; exocytosis
ARFIP2ruffle organization; actin cytoskeleton organization; lamellipodium assembly; small GTPase mediated signal transduction; cellular component movement
ARFRP1protein localization in Golgi apparatus; retrograde transport, endosome to Golgi; Golgi to plasma membrane protein transport; gastrulation; small GTPase mediated signal transduction; signal transduction; GTP catabolic process
ARGFX-
ARHGAP10regulation of small GTPase mediated signal transduction; filopodium assembly; regulation of apoptotic process; small GTPase mediated signal transduction; signal transduction; cytoskeleton organization; apoptotic process
ARHGAP11Aregulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction
ARHGAP12regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction
ARHGAP15small GTPase mediated signal transduction; positive regulation of Rac GTPase activity; signal transduction; regulation of small GTPase mediated signal transduction; regulation of cell shape
ARHGAP17regulation of small GTPase mediated signal transduction; calcium ion-dependent exocytosis; small GTPase mediated signal transduction; signal transduction; actin filament organization
ARHGAP19regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction
ARHGAP21signal transduction
ARHGAP22signal transduction; regulation of small GTPase mediated signal transduction; cell differentiation; multicellular organismal development; small GTPase mediated signal transduction; regulation of transcription, DNA-dependent; angiogenesis
ARHGAP24cell differentiation; angiogenesis; multicellular organismal development; signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction
ARHGAP25regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction
ARHGAP28regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction
ARHGAP29Rho protein signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; positive regulation of Rho GTPase activity
ARHGAP30signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction
ARHGAP31regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction
ARHGAP32signal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
ARHGAP33protein transport; signal transduction
ARHGAP36signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction
ARHGAP39signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction; axon guidance
ARHGAP4regulation of small GTPase mediated signal transduction; apoptotic process; cytoskeleton organization; signal transduction; small GTPase mediated signal transduction; Rho protein signal transduction; induction of apoptosis by extracellular signals; positive regulation of Rho GTPase activity; nerve growth factor receptor signaling pathway
ARHGAP6actin filament organization; signal transduction; activation of phospholipase C activity; small GTPase mediated signal transduction; Rho protein signal transduction; positive regulation of phospholipase activity; actin filament polymerization; positive regulation of Rho GTPase activity; regulation of GTPase activity; regulation of small GTPase mediated signal transduction; negative regulation of stress fiber assembly; negative regulation of focal adhesion assembly
ARHGAP9small GTPase mediated signal transduction; signal transduction; regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity
ARHGDIBsmall GTPase mediated signal transduction; actin cytoskeleton organization; negative regulation of cell adhesion; Rho protein signal transduction; multicellular organismal development; immune response; cellular component movement; regulation of small GTPase mediated signal transduction
ARHGDIGregulation of small GTPase mediated signal transduction; Rho protein signal transduction; regulation of protein localization; regulation of catalytic activity; negative regulation of cell adhesion; small GTPase mediated signal transduction
ARHGEF1Rho protein signal transduction; termination of G-protein coupled receptor signaling pathway; regulation of Rho protein signal transduction; negative regulation of axonogenesis; nerve growth factor receptor signaling pathway; cell proliferation; regulation of axonogenesis
ARHGEF10myelination in peripheral nervous system; spindle assembly involved in mitosis; positive regulation of stress fiber assembly; centrosome duplication; regulation of Rho protein signal transduction; positive regulation of GTP catabolic process
ARHGEF10Lpositive regulation of stress fiber assembly; positive regulation of transcription via sterol regulatory element binding; regulation of Rho protein signal transduction; positive regulation of Rho GTPase activity
ARHGEF11Rho protein signal transduction; apoptotic process; regulation of cell growth; cytokinesis; cellular component movement; striated muscle contraction; small GTPase mediated signal transduction; actin cytoskeleton organization; regulation of Rho protein signal transduction; termination of G-protein coupled receptor signaling pathway; positive regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction; establishment of cell polarity; induction of apoptosis by extracellular signals; axon guidance; G-protein coupled receptor signaling pathway
ARHGEF12apoptotic process; G-protein coupled receptor signaling pathway; small GTPase mediated signal transduction; axon guidance; induction of apoptosis by extracellular signals; regulation of Rho protein signal transduction; termination of G-protein coupled receptor signaling pathway; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction
ARHGEF15regulation of catalytic activity; regulation of Rho protein signal transduction; positive regulation of stress fiber assembly; negative regulation of synapse maturation
ARHGEF16positive regulation of establishment of protein localization in plasma membrane; nerve growth factor receptor signaling pathway; apoptotic process; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals; regulation of Rho protein signal transduction; activation of Cdc42 GTPase activity; regulation of small GTPase mediated signal transduction; activation of Rac GTPase activity; cell chemotaxis
ARHGEF17regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; small GTPase mediated signal transduction; apoptotic process; actin cytoskeleton organization
ARHGEF18regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; apoptotic process; small GTPase mediated signal transduction; regulation of cell shape; induction of apoptosis by extracellular signals; actin cytoskeleton organization; regulation of Rho protein signal transduction
ARHGEF19regulation of Rho protein signal transduction; wound healing; positive regulation of Rho GTPase activity; regulation of actin cytoskeleton organization
ARHGEF2induction of apoptosis by extracellular signals; regulation of cell proliferation; intracellular signal transduction; regulation of Rho protein signal transduction; nerve growth factor receptor signaling pathway; negative regulation of neurogenesis; regulation of small GTPase mediated signal transduction; positive regulation of NF-kappaB transcription factor activity; cell division; establishment of mitotic spindle orientation; cell morphogenesis; intracellular protein transport; small GTPase mediated signal transduction; mitosis; cell cycle; negative regulation of microtubule depolymerization; apoptotic process; actin filament organization
ARHGEF3nerve growth factor receptor signaling pathway; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; apoptotic process; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; Rho protein signal transduction
ARHGEF37regulation of Rho protein signal transduction
ARHGEF38regulation of Rho protein signal transduction
ARHGEF4regulation of Rho protein signal transduction; apoptotic process; small GTPase mediated signal transduction; induction of apoptosis by extracellular signals; lamellipodium assembly; intracellular signal transduction; filopodium assembly; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction
ARHGEF40regulation of Rho protein signal transduction
ARHGEF6induction of apoptosis by extracellular signals; nerve growth factor receptor signaling pathway; positive regulation of GTPase activity; regulation of Rho protein signal transduction; cell junction assembly; regulation of small GTPase mediated signal transduction; apoptotic process; JNK cascade; small GTPase mediated signal transduction
ARHGEF7positive regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; regulation of Rho protein signal transduction; nervous system development; induction of apoptosis by extracellular signals; epidermal growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction; apoptotic process
ARID1Achromatin-mediated maintenance of transcription; chromatin organization; nucleosome disassembly; intracellular estrogen receptor signaling pathway; nervous system development; regulation of transcription from RNA polymerase II promoter; androgen receptor signaling pathway; nucleosome mobilization; glucocorticoid receptor signaling pathway; positive regulation of transcription, DNA-dependent; chromatin remodeling
ARID1Bregulation of transcription, DNA-dependent; nervous system development; chromatin modification; chromatin-mediated maintenance of transcription
ARID2nucleosome disassembly; regulation of transcription, DNA-dependent; chromatin modification
ARID3Aregulation of transcription, DNA-dependent
ARID3Cregulation of transcription, DNA-dependent
ARID4Anegative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter
ARID4Bregulation of transcription, DNA-dependent
ARID5Anegative regulation of transcription, DNA-dependent
ARID5Bmuscle organ morphogenesis; positive regulation of sequence-specific DNA binding transcription factor activity; kidney development; liver development; nitrogen compound metabolic process; male gonad development; female gonad development; post-embryonic development; fibroblast migration; adrenal gland development; multicellular organism growth; skeletal system morphogenesis; palate development; adipose tissue development; face morphogenesis; fat pad development; negative regulation of transcription, DNA-dependent; platelet-derived growth factor receptor signaling pathway; cell development; fat cell differentiation
ARIH1ubiquitin-dependent protein catabolic process; protein ubiquitination; cytokine-mediated signaling pathway
ARIH2protein K63-linked ubiquitination; protein K48-linked ubiquitination; hemopoietic stem cell proliferation; developmental cell growth; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; multicellular organismal development; protein polyubiquitination
ARL11small GTPase mediated signal transduction
ARL2positive regulation of microtubule polymerization; centrosome organization; maintenance of protein location in nucleus; negative regulation of GTPase activity; tight junction assembly; regulation of microtubule polymerization; acetylcholine transport; small GTPase mediated signal transduction; cell cycle; tubulin complex assembly; GTP catabolic process; positive regulation of cell-substrate adhesion
ARL3small GTPase mediated signal transduction; cilium morphogenesis; photoreceptor cell development; protein transport; cell cycle; kidney development; cytokinesis
ARL4Cendocytic recycling; small GTPase mediated signal transduction; transport; GTP catabolic process
ARL5Asmall GTPase mediated signal transduction
ARL6IP5negative regulation of transport; L-glutamate transport
ARL8Acell division; GTP catabolic process; cell cycle; chromosome segregation; mitosis; small GTPase mediated signal transduction
ARMC12-
ARMC3-
ARMC4-
ARMC5-
ARMC6-
ARMC9-
ARMCX1-
ARMCX2-
ARMCX3-
ARMCX5-
ARNTresponse to hypoxia; embryonic placenta development; positive regulation of endothelial cell proliferation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation vascular endothelial growth factor production; cell differentiation; positive regulation of vascular endothelial growth factor receptor signaling pathway; mRNA transcription from RNA polymerase II promoter; positive regulation of protein sumoylation; positive regulation of hormone biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of glycolysis; positive regulation of erythrocyte differentiation; regulation of transcription from RNA polymerase II promoter in response to oxidative stress
ARNT2response to hypoxia; in utero embryonic development; regulation of transcription, DNA-dependent; central nervous system development; positive regulation of cell proliferation; response to estradiol stimulus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process
ARNTLcircadian rhythm; positive regulation of transcription from RNA polymerase II promoter
ARNTL2regulation of transcription, DNA-dependent; entrainment of circadian clock; circadian rhythm; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter
ARPC1Aregulation of actin filament polymerization; actin cytoskeleton organization
ARPC1Bregulation of actin filament polymerization; cellular component movement
ARPP21cellular response to heat
ARRB1post-Golgi vesicle-mediated transport; negative regulation of signal transduction; blood coagulation; cellular membrane organization; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; G-protein coupled receptor internalization; protein transport; protein ubiquitination; positive regulation of ERK1 and ERK2 cascade; positive regulation of transcription from RNA polymerase II promoter; histone H4 acetylation; positive regulation of GTPase activity; proteasomal ubiquitin-dependent protein catabolic process; stress fiber assembly; negative regulation of catalytic activity; positive regulation of histone acetylation; positive regulation of Rho protein signal transduction; negative regulation of interleukin-8 production; negative regulation of interleukin-6 production; negative regulation of NF-kappaB transcription factor activity; negative regulation of protein ubiquitination; platelet activation
ARRDC1-AS1-
ARRDC2-
ARRDC3signal transduction
ARSD-
ARSF-
ARSGsulfur compound metabolic process
ARSH-
ARSI-
ARSJ-
ARSK-
ARV1sphingolipid metabolic process; lipid metabolic process
ARVCFcell adhesion; multicellular organismal development
ARXcell proliferation in forebrain; positive regulation of organ growth; regulation of cell proliferation; cell differentiation; neuron migration; multicellular organismal development; nervous system development; axon guidance; globus pallidus development; olfactory bulb development; cerebral cortex tangential migration; embryonic olfactory bulb interneuron precursor migration; cerebral cortex GABAergic interneuron migration
ASAH2small molecule metabolic process; sphingolipid metabolic process; lipid metabolic process; glycosphingolipid metabolic process; ceramide metabolic process; apoptotic process; signal transduction
ASAP2positive regulation of catalytic activity; regulation of ARF GTPase activity
ASAP3regulation of ARF GTPase activity
ASB11intracellular signal transduction
ASB14intracellular signal transduction
ASB15intracellular signal transduction
ASB17intracellular signal transduction
ASB2intracellular signal transduction; signal transduction
ASB4intracellular signal transduction
ASB5intracellular signal transduction
ASB9protein ubiquitination; intracellular signal transduction; positive regulation of protein catabolic process
ASCC2regulation of transcription, DNA-dependent
ASCC3regulation of transcription, DNA-dependent
ASCL3regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
ASCL4skin development; regulation of transcription from RNA polymerase II promoter
ASGR1receptor-mediated endocytosis; cellular response to extracellular stimulus
ASGR2regulation of protein stability; lipid homeostasis; bone mineralization; glycoprotein metabolic process; cell surface receptor signaling pathway; endocytosis
ASH1Lregulation of transcription, DNA-dependent; DNA packaging; transcription from RNA polymerase II promoter; cell-cell signaling; chromatin modification
ASH2Lpositive regulation of transcription from RNA polymerase II promoter; histone H3-K4 methylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; response to DNA damage stimulus; positive regulation of cell proliferation; chromatin modification; hemopoiesis; response to estrogen stimulus
ASIC1signal transduction; response to pH; calcium ion transport; sodium ion transport; ion transport; transport
ASIC3transport; ion transport; signal transduction; sensory perception; sodium ion transmembrane transport
ASIC5ion transport
ASIPmelanosome transport; genetic imprinting; pigmentation; regulation of molecular function, epigenetic; melanin biosynthetic process; melanosome organization; hormone-mediated signaling pathway; adult feeding behavior; cell-cell signaling; signal transduction; generation of precursor metabolites and energy
ASLcellular response to dexamethasone stimulus; cellular response to hypoxia; cellular response to glucagon stimulus; cellular response to tumor necrosis factor; cellular response to interferon-gamma; cellular response to cAMP; cellular response to ammonium ion; diaphragm development; response to growth hormone stimulus; response to steroid hormone stimulus; small molecule metabolic process; response to drug; arginine biosynthetic process via ornithine; response to lipopolysaccharide; urea cycle; argininosuccinate metabolic process; response to acid; kidney development; liver development; internal protein amino acid acetylation; arginine catabolic process; midgut development; aging; response to nutrient; locomotory behavior; cellular amino acid biosynthetic process; post-embryonic development; response to zinc ion; response to amine stimulus; ammonia assimilation cycle; cellular nitrogen compound metabolic process
ASNA1detoxification of arsenic-containing substance; transport; arsenite transport
ASNSD1asparagine biosynthetic process; glutamine metabolic process; cellular amino acid biosynthetic process
ASPHpattern specification process; palate development; peptidyl-aspartic acid hydroxylation; limb morphogenesis; peptidyl-amino acid modification; negative regulation of cell proliferation; face morphogenesis; muscle contraction
ASPHD1peptidyl-amino acid modification
ASPMcell division; cell cycle; mitosis; forebrain neuroblast division; negative regulation of neuron differentiation; negative regulation of asymmetric cell division; maintenance of centrosome location
ASPNbone mineralization; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of tooth mineralization
ASPRV1skin development; proteolysis; protein processing
ASPSCR1intracellular protein transport; glucose homeostasis; regulation of glucose import
ASTE1DNA repair
ASTLproteolysis
ASTN1cell migration; neuron cell-cell adhesion; cell adhesion
ASTN2-
ASUNregulation of mitotic cell cycle; sperm motility; cell division; regulation of fertilization; cell cycle; mitosis
ASXL1regulation of transcription, DNA-dependent; chromatin modification
ATAD2regulation of transcription, DNA-dependent
ATE1protein arginylation
ATF5negative regulation of astrocyte differentiation; negative regulation of neurogenesis; regulation of transcription from RNA polymerase II promoter; anti-apoptosis
ATF6regulation of transcription from RNA polymerase II promoter; protein folding; response to stress; endoplasmic reticulum unfolded protein response; signal transduction; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; activation of signaling protein activity involved in unfolded protein response; response to unfolded protein
ATF7IPinterspecies interaction between organisms; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; DNA methylation; regulation of RNA polymerase II transcriptional preinitiation complex assembly; negative regulation of transcription from RNA polymerase II promoter
ATF7IP2regulation of transcription, DNA-dependent
ATG16L1autophagic vacuole assembly; autophagy; protein transport; protein homooligomerization
ATG16L2autophagy; protein transport
ATG2A-
ATG2B-
ATG4Aproteolysis; autophagy; protein transport
ATG7neurological system process; negative regulation of apoptotic process; response to starvation; cardiac muscle cell development; central nervous system neuron axonogenesis; pyramidal neuron development; cerebral cortex development; protein catabolic process; neuron projection development; regulation of protein ubiquitination; positive regulation of protein modification process; protein modification by small protein conjugation; cerebellar Purkinje cell layer development; protein modification process; protein transport; adult walking behavior; organelle organization; cellular membrane fusion; autophagy; cellular amino acid metabolic process; protein lipidation; liver development; post-embryonic development
ATHL1carbohydrate metabolic process
ATICsmall molecule metabolic process; organ regeneration; purine ribonucleoside monophosphate biosynthetic process; purine nucleotide biosynthetic process; purine base metabolic process; nucleobase-containing compound metabolic process; nucleobase-containing small molecule metabolic process
ATL1endoplasmic reticulum organization; GTP catabolic process; protein homooligomerization; cell death; axonogenesis
ATL2GTP catabolic process; protein homooligomerization; Golgi organization; ER to Golgi vesicle-mediated transport; endoplasmic reticulum organization
ATMresponse to ionizing radiation; peptidyl-serine phosphorylation; negative regulation of B cell proliferation; female gamete generation; G2/M transition DNA damage checkpoint; DNA damage response, signal transduction resulting in induction of apoptosis; cell death; heart development; brain development; DNA repair; phosphatidylinositol-3-phosphate biosynthetic process; lipoprotein catabolic process; positive regulation of apoptotic process; negative regulation of apoptotic process; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of neuron apoptosis; protein autophosphorylation; regulation of cell cycle; histone mRNA catabolic process; cellular response to gamma radiation; reciprocal meiotic recombination; replicative senescence; cell cycle checkpoint; double-strand break repair via homologous recombination; response to hypoxia; somitogenesis; pre-B cell allelic exclusion; double-strand break repair; response to DNA damage stimulus; DNA damage induced pr
ATN1cell migration; maintenance of cell polarity; regulation of neuron differentiation; toxin metabolic process; cell death; central nervous system development; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; neuron apoptosis
ATOH1transcription from RNA polymerase II promoter; axon guidance; multicellular organismal development; apoptotic process; auditory receptor cell fate determination; central nervous system development; brain development; cerebral cortex development; inner ear morphogenesis; auditory receptor cell fate specification; regulation of transcription, DNA-dependent; neuron migration; positive regulation of auditory receptor cell differentiation; positive regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter
ATP10Atransmembrane transport; cation transport; phospholipid translocation; ion transmembrane transport; regulation of cell shape
ATP10Bphospholipid translocation; cation transport
ATP10Dion transmembrane transport; phospholipid translocation; transmembrane transport; cation transport
ATP11Acation transport; phospholipid translocation
ATP11Bion transmembrane transport; phospholipid translocation; transmembrane transport; aminophospholipid transport; ion transport; cation transport
ATP11Cphospholipid translocation; ion transmembrane transport; cation transport; transmembrane transport
ATP12Apotassium ion transport; transmembrane transport; ion transmembrane transport; proton transport; ATP biosynthetic process
ATP13A2cation transport
ATP13A3cation transport
ATP13A4cation transport; ATP biosynthetic process
ATP13A5cation transport; ATP biosynthetic process
ATP1A2regulation of vasoconstriction; ATP hydrolysis coupled proton transport; regulation of blood pressure; visual learning; adult locomotory behavior; negative regulation of striated muscle contraction; ion transmembrane transport; locomotion; negative regulation of heart contraction; transmembrane transport; reduction of cytosolic calcium ion concentration; regulation of smooth muscle contraction; sodium ion transport; potassium ion transport; ATP biosynthetic process; regulation of respiratory gaseous exchange by neurological system process; regulation of the force of heart contraction; neurotransmitter uptake; regulation of striated muscle contraction
ATP1A3visual learning; transmembrane transport; response to drug; ionotropic glutamate receptor signaling pathway; ion transmembrane transport; adult locomotory behavior; memory; potassium ion transport; sodium ion transport; ATP biosynthetic process
ATP1A4transmembrane transport; ion transmembrane transport; regulation of cellular pH; sperm motility; ATP hydrolysis coupled proton transport; sodium ion transport; potassium ion transport; ATP biosynthetic process
ATP1B1response to hypoxia; ATP biosynthetic process; transport; potassium ion transport; sodium ion transport; leukocyte migration; ion transmembrane transport; blood coagulation; transmembrane transport
ATP1B4regulation of transcription, DNA-dependent; transport; potassium ion transport; sodium ion transport; monovalent inorganic cation transport; ATP metabolic process
ATP2A1blood coagulation; reduction of endoplasmic reticulum calcium ion concentration; elevation of endoplasmic reticulum calcium ion concentration; positive regulation of fast-twitch skeletal muscle fiber contraction; apoptotic mitochondrial changes; ATP catabolic process; ATP biosynthetic process; cation transport; calcium ion transport; regulation of striated muscle contraction; ion transmembrane transport; response to endoplasmic reticulum stress; negative regulation of striated muscle contraction; elevation of mitochondrial calcium ion concentration; maintenance of mitochondrion location; transmembrane transport; apoptosis in response to endoplasmic reticulum stress; calcium ion import; relaxation of skeletal muscle
ATP2A2ATP biosynthetic process; ion transmembrane transport; transport; cation transport; cell adhesion; blood coagulation; epidermis development; transmembrane transport; sarcoplasmic reticulum calcium ion transport
ATP2A3transport; transmembrane transport; ion transmembrane transport; blood coagulation; calcium ion transport; cation transport; ATP biosynthetic process
ATP2B1calcium ion transmembrane transport; transmembrane transport; ion transmembrane transport; blood coagulation; cation transport; transport; ATP biosynthetic process
ATP2B2blood coagulation; cation transport; calcium ion transport; organelle organization; brain development; lactation; cell morphogenesis; sensory perception of sound; locomotory behavior; regulation of cell size; cerebellum development; cerebellar Purkinje cell layer morphogenesis; cerebellar Purkinje cell differentiation; cerebellar granule cell differentiation; neuron differentiation; ion transmembrane transport; locomotion; serotonin metabolic process; inner ear morphogenesis; ATP biosynthetic process; cochlea development; calcium ion transmembrane transport; inner ear receptor cell differentiation; auditory receptor cell stereocilium organization; transmembrane transport; positive regulation of calcium ion transport; cytosolic calcium ion homeostasis; detection of mechanical stimulus involved in sensory perception of sound; neuromuscular process controlling balance; synapse organization; regulation of synaptic plasticity; cGMP metabolic process; otolith mineralization; neural retina development; ATP catabolic
ATP2B3transport; ATP biosynthetic process; cation transport; blood coagulation; ion transmembrane transport; transmembrane transport; calcium ion transmembrane transport
ATP2B4neural retina development; ATP biosynthetic process; transport; cation transport; blood coagulation; ion transmembrane transport; transmembrane transport; calcium ion transmembrane transport
ATP2C1signal transduction; Golgi calcium ion transport; ion transmembrane transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; transmembrane transport; Golgi calcium ion homeostasis; manganese ion transport; calcium ion transport; cation transport; ATP biosynthetic process; cellular calcium ion homeostasis; epidermis development; calcium-dependent cell-cell adhesion; cellular manganese ion homeostasis; actin cytoskeleton reorganization
ATP5Bgeneration of precursor metabolites and energy; angiogenesis; small molecule metabolic process; mitochondrial ATP synthesis coupled proton transport; respiratory electron transport chain; proton transport; ATP hydrolysis coupled proton transport; regulation of intracellular pH; negative regulation of cell adhesion involved in substrate-bound cell migration; receptor-mediated endocytosis; ion transport; transport; ATP biosynthetic process; lipid metabolic process; ATP catabolic process; ADP biosynthetic process
ATP5C1oxidative phosphorylation; ATP catabolic process; ATP biosynthetic process; ion transport; small molecule metabolic process; mitochondrial ATP synthesis coupled proton transport; respiratory electron transport chain; proton transport
ATP5G2transport; ion transport; ATP synthesis coupled proton transport; ATP hydrolysis coupled proton transport
ATP5G3ATP hydrolysis coupled proton transport; response to ethanol; ATP synthesis coupled proton transport; aging; ion transport; transport
ATP5JATP catabolic process; transport; ion transport; mitochondrial ATP synthesis coupled proton transport; respiratory electron transport chain; small molecule metabolic process
ATP5Sproton transport; ATP biosynthetic process; ion transport
ATP5SL-
ATP6AP1ion transport; proton transport; ATP hydrolysis coupled proton transport; cell death; aging
ATP6V0A1ion transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; transmembrane transport; transferrin transport
ATP6V0A2transmembrane transport; transferrin transport; insulin receptor signaling pathway; immune response; cellular iron ion homeostasis; ion transport; ATP hydrolysis coupled proton transport
ATP6V0A4insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; transmembrane transport; sensory perception of sound; excretion; regulation of pH; cellular iron ion homeostasis; ion transport; ossification
ATP6V0Bion transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; transmembrane transport
ATP6V0CATP hydrolysis coupled proton transport; transmembrane transport; interspecies interaction between organisms; transferrin transport; proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; ion transport
ATP6V0D1proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; brain development; activation of signaling protein activity involved in unfolded protein response; cellular iron ion homeostasis; ATP catabolic process; transmembrane transport; ion transmembrane transport; transferrin transport; endoplasmic reticulum unfolded protein response
ATP6V0D2ion transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; transferrin transport; transmembrane transport
ATP6V1B1transmembrane transport; calcium ion homeostasis; ATP metabolic process; insulin receptor signaling pathway; pH reduction; inner ear morphogenesis; ion transmembrane transport; transferrin transport; sensory perception of sound; excretion; regulation of pH; cellular iron ion homeostasis; ossification; proton transport; ATP hydrolysis coupled proton transport
ATP6V1B2transmembrane transport; ATP metabolic process; transferrin transport; proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; ion transport
ATP6V1C1insulin receptor signaling pathway; transmembrane transport; ion transmembrane transport; ATP catabolic process; transport; cellular iron ion homeostasis; ATP hydrolysis coupled proton transport; proton transport; transferrin transport
ATP6V1C2ATP catabolic process; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; transferrin transport; ion transmembrane transport; transmembrane transport
ATP6V1E1ion transport; transferrin transport; proton transport; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; transmembrane transport
ATP6V1E2transferrin transport; cellular iron ion homeostasis; insulin receptor signaling pathway; ATP hydrolysis coupled proton transport; proton transport; ion transport; transmembrane transport
ATP6V1G1transmembrane transport; ion transmembrane transport; proton transport; insulin receptor signaling pathway; cellular iron ion homeostasis; transferrin transport
ATP7AT-helper cell differentiation; epinephrine metabolic process; norepinephrine metabolic process; peptidyl-lysine modification; dopamine metabolic process; hindlimb morphogenesis; ion transmembrane transport; hair follicle morphogenesis; collagen fibril organization; extracellular matrix organization; metal ion transport; central nervous system neuron development; pyramidal neuron development; cerebellar Purkinje cell differentiation; removal of superoxide radicals; elastin biosynthetic process; norepinephrine biosynthetic process; serotonin metabolic process; positive regulation of catalytic activity; pigmentation; neuroprotection; skin development; ATP metabolic process; elastic fiber assembly; lung alveolus development; negative regulation of metalloenzyme activity; positive regulation of metalloenzyme activity; neuron projection morphogenesis; dendrite morphogenesis; cartilage development; positive regulation of oxidoreductase activity; regulation of gene expression; copper ion export; transmembrane transpo
ATP7BATP catabolic process; ATP biosynthetic process; copper ion transport; cellular copper ion homeostasis; cellular zinc ion homeostasis; lactation; copper ion import; intracellular copper ion transport; metal ion transport; ion transmembrane transport; response to copper ion; sequestering of calcium ion; transmembrane transport; copper ion export
ATP8A1ion transmembrane transport; cation transport; aminophospholipid transport; phospholipid translocation; transmembrane transport
ATP8A2phospholipid transport; negative regulation of cell proliferation; cation transport
ATP8B1transmembrane transport; ATP catabolic process; cation transport; bile acid metabolic process; bile acid and bile salt transport; ion transmembrane transport; phospholipid translocation; negative regulation of transcription, DNA-dependent
ATP8B2transmembrane transport; ATP catabolic process; cation transport; phospholipid transport; ion transmembrane transport
ATP8B4phospholipid transport; cation transport
ATP9Aphospholipid translocation; cation transport
ATP9Bestablishment of protein localization in Golgi; cation transport; aminophospholipid transport; phospholipid translocation
ATRcell cycle checkpoint; regulation of protein binding; positive regulation of DNA damage response, signal transduction by p53 class mediator; protein autophosphorylation; replicative senescence; cellular response to UV; cellular response to gamma radiation; DNA damage checkpoint; peptidyl-serine phosphorylation; negative regulation of DNA replication; multicellular organismal development; cell cycle; response to DNA damage stimulus; protein phosphorylation; DNA repair; DNA replication
ATRIPDNA repair; DNA replication; DNA damage checkpoint; cell cycle checkpoint
ATRNpigmentation; inflammatory response; response to oxidative stress; regulation of multicellular organism growth
ATRNL1G-protein coupled receptor signaling pathway
ATRXDNA duplex unwinding; forebrain development; regulation of transcription, DNA-dependent; DNA recombination; DNA methylation; DNA repair
ATXN1adult locomotory behavior; regulation of excitatory postsynaptic membrane potential; nuclear export; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of phosphorylation; visual learning; cell death; RNA processing
ATXN2homeostasis of number of cells; RNA transport; neuromuscular process; neuron projection morphogenesis; negative regulation of multicellular organism growth; stress granule assembly; cerebellar Purkinje cell differentiation; RNA metabolic process; regulation of translation; cell death; cytoplasmic mRNA processing body assembly
ATXN2L-
ATXN7L2-
ATXN7L3histone deubiquitination; chromatin modification; positive regulation of transcription, DNA-dependent
AUHmRNA catabolic process; branched chain family amino acid catabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process
AUP1-
AURKAphosphatidylinositol-mediated signaling; protein autophosphorylation; regulation of centrosome cycle; positive regulation of mitosis; response to estradiol stimulus; regulation of protein stability; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell projection organization; mitosis; spindle organization; cell cycle; protein phosphorylation; mitotic cell cycle; cell division
AURKAIP1positive regulation of proteolysis; negative regulation of mitosis
AUTS2-
AVENanti-apoptosis; apoptotic process
AVILresponse to stress; cytoskeleton organization; nervous system development; positive regulation of neuron projection development; actin filament capping; cilium morphogenesis
AVL9-
AVPI1activation of MAPK activity; cell cycle
AVPR1AG-protein coupled receptor signaling pathway; response to stress; positive regulation of vasoconstriction; generation of precursor metabolites and energy; calcium-mediated signaling; penile erection; sperm ejaculation; maternal behavior; cellular response to water deprivation; positive regulation of renal sodium excretion; social behavior; positive regulation of cellular pH reduction; positive regulation of prostaglandin biosynthetic process; positive regulation of cell growth; telencephalon development; activation of phospholipase C activity; myotube differentiation; positive regulation of glutamate secretion; positive regulation of heart rate; response to inorganic substance; response to organic substance; positive regulation of cell proliferation; blood circulation; grooming behavior; negative regulation of female receptivity; elevation of cytosolic calcium ion concentration; maternal aggressive behavior; regulation of systemic arterial blood pressure by vasopressin; response to corticosterone stimulus; ne
AVPR1Bpositive regulation of cellular pH reduction; positive regulation of blood pressure; hyperosmotic salinity response; positive regulation of glutamate secretion; positive regulation of heart rate; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor signaling pathway; response to stress; regulation of systemic arterial blood pressure by vasopressin
AVPR2positive regulation of systemic arterial blood pressure; water transport; G-protein signaling, coupled to cAMP nucleotide second messenger; activation of adenylate cyclase activity; I-kappaB kinase/NF-kappaB cascade; excretion; hemostasis; positive regulation of cell proliferation; positive regulation of gene expression; telencephalon development; response to cytokine stimulus; negative regulation of urine volume; negative regulation of renal sodium excretion; transmembrane transport; interferon-gamma production
AWAT1lipid biosynthetic process
AXDND1-
AXIN1cytoplasmic microtubule organization; protein polyubiquitination; in utero embryonic development; optic placode formation; positive regulation of protein phosphorylation; nucleocytoplasmic transport; apoptotic process; signal transduction; activation of JUN kinase activity; erythrocyte homeostasis; positive regulation of peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; activation of protein kinase activity; positive regulation of protein ubiquitination; cell death; olfactory placode formation; positive regulation of transforming growth factor beta receptor signaling pathway; multicellular organismal development; determination of left/right symmetry; negative regulation of Wnt receptor signaling pathway; sensory perception of sound; positive regulation of protein catabolic process; Wnt receptor signaling pathway involved in forebrain neuron fate commitment; forebrain anterior/posterior pattern specification; hemoglobin metabolic process; positiv
AXLprotein kinase B signaling cascade; apoptotic cell clearance; ovulation cycle; substrate adhesion-dependent cell spreading; erythrocyte homeostasis; secretion by cell; negative regulation of tumor necrosis factor production; cellular response to extracellular stimulus; platelet activation; cell differentiation; forebrain cell migration; spermatogenesis; enzyme linked receptor protein signaling pathway; signal transduction; inflammatory response; blood vessel remodeling; natural killer cell differentiation; neuron migration; innate immune response; negative regulation of lymphocyte activation; vagina development; negative regulation of neuron apoptosis
AZIN2small molecule metabolic process; ornithine metabolic process; polyamine metabolic process; polyamine biosynthetic process; spermatogenesis; agmatine biosynthetic process; cellular nitrogen compound metabolic process; positive regulation of catalytic activity
AZU1macrophage chemotaxis; positive regulation of cell adhesion; positive regulation of MHC class II biosynthetic process; cellular extravasation; regulation of vascular permeability; positive regulation of tumor necrosis factor biosynthetic process; monocyte activation; glial cell migration; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; inflammatory response; chemotaxis; anti-apoptosis; proteolysis; microglial cell activation; positive regulation of fractalkine biosynthetic process; positive regulation of phagocytosis; defense response to Gram-negative bacterium; induction of positive chemotaxis; positive regulation of interleukin-1 beta biosynthetic process
B2Mantigen processing and presentation of exogenous peptide antigen via MHC class I; interferon-gamma-mediated signaling pathway; regulation of immune response; regulation of defense response to virus by virus; cytokine-mediated signaling pathway; viral reproduction; immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I
B3GALNT1oligosaccharide biosynthetic process; protein glycosylation
B3GALT1protein glycosylation; oligosaccharide biosynthetic process; lipid glycosylation
B3GALT5protein glycosylation
B3GAT1metabolic process; carbohydrate metabolic process
B3GAT2-
B3GNT2protein glycosylation; axon guidance; sensory perception of smell; O-glycan processing; post-translational protein modification; cellular protein metabolic process
B3GNT4O-glycan processing; post-translational protein modification; cellular protein metabolic process; protein glycosylation
B3GNT8post-translational protein modification; cellular protein metabolic process; protein glycosylation; O-glycan processing; poly-N-acetyllactosamine biosynthetic process
B4GALNT2UDP-N-acetylglucosamine metabolic process; protein glycosylation; UDP-N-acetylgalactosamine metabolic process; negative regulation of cell-cell adhesion; lipid glycosylation
B4GALNT3-
B4GALNT4-
B4GALT1post-translational protein modification; development of secondary sexual characteristics; mammary gland development; extracellular matrix organization; protein N-linked glycosylation via asparagine; oligosaccharide biosynthetic process; negative regulation of cell proliferation; penetration of zona pellucida; binding of sperm to zona pellucida; cell adhesion; protein glycosylation; galactose metabolic process; lactose biosynthetic process; carbohydrate metabolic process; acute inflammatory response; epithelial cell development; branching morphogenesis of a tube; leukocyte migration; regulation of cellular component movement; regulation of acrosome reaction; positive regulation of epithelial cell proliferation involved in wound healing; angiogenesis involved in wound healing; positive regulation of apoptosis involved in mammary gland involution; cellular protein metabolic process
B4GALT2cellular protein metabolic process; post-translational protein modification; carbohydrate metabolic process; protein N-linked glycosylation via asparagine
B4GALT3carbohydrate metabolic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process
B4GALT6cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine; carbohydrate metabolic process
B4GALT7negative regulation of fibroblast proliferation; carbohydrate metabolic process; fibril organization; glycosaminoglycan biosynthetic process; protein modification process; proteoglycan metabolic process
B9D2M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; cell projection organization; cilium assembly
BAALC-
BAATliver development; bile acid conjugation; glycine metabolic process; lipid metabolic process; fatty acid metabolic process; acyl-CoA metabolic process; bile acid biosynthetic process; bile acid metabolic process; taurine metabolic process; organ regeneration; small molecule metabolic process; bile acid and bile salt transport
BACE1proteolysis; membrane protein ectodomain proteolysis; beta-amyloid metabolic process
BACH1regulation of transcription involved in G1/S phase of mitotic cell cycle; regulation of transcription involved in G2/M-phase of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to hypoxia
BACH2-
BAG1anti-apoptosis; response to stress; cell surface receptor signaling pathway; response to lithium ion; response to nicotine; response to drug; positive regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; chaperone cofactor-dependent protein refolding; neuron differentiation
BAG2protein folding; protein metabolic process
BAG3brain development; spinal cord development; protein folding; anti-apoptosis
BAG4cellular response to tumor necrosis factor; protein folding; anti-apoptosis
BAG5neuron death; negative regulation of protein refolding; negative regulation of ubiquitin-protein ligase activity; negative regulation of protein ubiquitination; protein folding; regulation of inclusion body assembly
BAHD1negative regulation of transcription, DNA-dependent; heterochromatin assembly; chromatin modification
BAIAP2response to bacterium; filopodium assembly; signal transduction; axonogenesis; insulin receptor signaling pathway; regulation of actin cytoskeleton organization
BAIAP2L1positive regulation of actin filament polymerization; filopodium assembly; response to bacterium; signal transduction; positive regulation of actin cytoskeleton reorganization
BAIAP3neurotransmitter secretion; G-protein coupled receptor signaling pathway
BANK1B cell activation
BAP1ubiquitin-dependent protein catabolic process; negative regulation of cell proliferation; protein K48-linked deubiquitination; regulation of cell cycle; monoubiquitinated histone H2A deubiquitination; protein deubiquitination; chromatin modification; regulation of cell growth; protein modification process; proteolysis
BARD1protein K6-linked ubiquitination; negative regulation of protein export from nucleus; positive regulation of protein catabolic process; negative regulation of apoptotic process; positive regulation of apoptotic process; regulation of phosphorylation; negative regulation of mRNA 3'-end processing; protein ubiquitination; spermatogenesis; cell cycle arrest; response to DNA damage stimulus; DNA repair; tissue homeostasis
BARHL2nervous system development; positive regulation of translation; regulation of axon extension; neuron differentiation; regulation of transcription from RNA polymerase II promoter; neuron migration; cell fate determination
BARX2myotube differentiation; catagen; negative regulation of transcription from RNA polymerase II promoter; cartilage condensation; positive regulation of transcription from RNA polymerase II promoter
BATFregulation of transcription, DNA-dependent
BAZ1Aregulation of transcription, DNA-dependent; transcription, DNA-dependent; chromatin remodeling; DNA-dependent DNA replication
BAZ1Bdouble-strand break repair; nucleosome disassembly; transcription, DNA-dependent; chromatin assembly or disassembly; heart morphogenesis; chromatin-mediated maintenance of transcription; regulation of transcription, DNA-dependent; response to DNA damage stimulus; histone phosphorylation; DNA replication-dependent nucleosome disassembly; regulation of gene expression, epigenetic; ATP-dependent chromatin remodeling
BAZ2Bregulation of transcription, DNA-dependent; transcription, DNA-dependent
BBOX1cellular nitrogen compound metabolic process; small molecule metabolic process; carnitine biosynthetic process
BBS10response to stimulus; chaperone-mediated protein complex assembly; nonmotile primary cilium assembly; photoreceptor cell maintenance; cellular protein metabolic process; retina homeostasis
BBS12cellular protein metabolic process; chaperone-mediated protein complex assembly
BBS2cilium morphogenesis; response to stimulus; brain morphogenesis; photoreceptor cell maintenance; fat cell differentiation; Golgi to plasma membrane protein transport; negative regulation of multicellular organism growth; protein localization to organelle; leptin-mediated signaling pathway; melanosome transport; negative regulation of appetite; adult behavior; cerebral cortex development; hippocampus development; striatum development; protein localization; sperm axoneme assembly; regulation of cilium beat frequency involved in ciliary motility
BBS4microtubule anchoring at centrosome; microtubule cytoskeleton organization; nonmotile primary cilium assembly; cilium assembly; fat cell differentiation; photoreceptor cell maintenance; positive regulation of flagellum assembly; retinal rod cell development; intracellular transport; brain morphogenesis; sensory processing; response to stimulus; centrosome organization; maintenance of protein location in nucleus; pigment granule aggregation in cell center; convergent extension involved in gastrulation; cilium morphogenesis; regulation of cilium beat frequency involved in ciliary motility; leptin-mediated signaling pathway; neural tube closure; retina homeostasis; heart looping; spermatid development; sensory perception of smell; dendrite development; regulation of lipid metabolic process; striatum development; cerebral cortex development; adult behavior; negative regulation of appetite; melanosome transport; regulation of cytokinesis; cell cycle cytokinesis; protein localization to organelle; hippocampus devel
BBS7digestive tract morphogenesis; cilium morphogenesis; pigment granule aggregation in cell center; response to stimulus; heart looping; determination of left/right symmetry; visual perception; melanosome transport; fat cell differentiation
BCAMcell adhesion; cell-matrix adhesion; signal transduction
BCANregulation of neuronal synaptic plasticity; hippocampus development; cell adhesion
BCAP29intracellular protein transport; apoptotic process; vesicle-mediated transport
BCAR3response to drug; signal transduction; small GTPase mediated signal transduction
BCAS1-
BCAS2RNA splicing, via transesterification reactions; mRNA processing; RNA splicing
BCAS3-
BCAS4-
BCDIN3D-
BCHEsynaptic transmission, cholinergic; response to folic acid; response to glucocorticoid stimulus; negative regulation of synaptic transmission; cocaine metabolic process; response to alkaloid; response to drug; choline metabolic process; metabolic process; learning; response to nutrient
BCKDHBcellular nitrogen compound metabolic process; response to cAMP; response to glucocorticoid stimulus; branched chain family amino acid catabolic process; response to nutrient; small molecule metabolic process
BCKDKphosphorylation; peptidyl-histidine phosphorylation; branched chain family amino acid catabolic process; cellular amino acid catabolic process
BCL11Anegative regulation of protein homooligomerization; negative regulation of gene expression; negative regulation of dendrite development; regulation of dendrite development; positive regulation of collateral sprouting; negative regulation of collateral sprouting; positive regulation of transcription from RNA polymerase II promoter; negative regulation of axon extension; B cell differentiation; T cell differentiation; hemopoiesis; protein sumoylation; negative regulation of neuron projection development; positive regulation of neuron projection development; regulation of transcription, DNA-dependent
BCL11Bnegative regulation of apoptotic process; keratinocyte development; alpha-beta T cell differentiation; thymus development; positive regulation of transcription from RNA polymerase II promoter; epithelial cell morphogenesis; regulation of lipid metabolic process; regulation of keratinocyte proliferation; central nervous system neuron differentiation; post-embryonic camera-type eye development; striatal medium spiny neuron differentiation; T cell differentiation in thymus; T cell receptor V(D)J recombination; odontogenesis of dentin-containing tooth; regulation of transcription, DNA-dependent; positive T cell selection; skin development; negative regulation of cell proliferation; axonogenesis
BCL2L1nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; growth; positive regulation of apoptotic process; negative regulation of apoptotic process; negative regulation of neuron apoptosis; innate immune response; positive regulation of anti-apoptosis; response to cycloheximide; regulation of mitochondrial membrane permeability; regulation of mitochondrial membrane potential; cellular process regulating host cell cycle in response to virus; cellular response to amino acid stimulus; cellular response to alkaloid; cellular response to gamma radiation; mitotic cell cycle G2/M transition checkpoint; negative regulation of establishment of protein localization in plasma membrane; response to cytokine stimulus; fertilization; response to radiation; apoptotic mitochondrial changes; negative regulation of survival gene product expression; induction of apoptosis by intracellular signals; male gonad development; positive regulation of cell proliferation; spermatogenesis; germ cell developme
BCL2L11thymus development; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of release of cytochrome c from mitochondria; cellular process regulating host cell cycle in response to virus; post-embryonic organ morphogenesis; spleen development; regulation of developmental pigmentation; nerve growth factor receptor signaling pathway; regulation of organ growth; ear development; activation of cysteine-type endopeptidase activity involved in apoptotic process; cell-matrix adhesion; spermatogenesis; male gonad development; induction of apoptosis by extracellular signals; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; post-embryonic development; positive regulation of cell cycle; induction of apoptosis; apoptotic process; myeloid cell homeostasis; mammary gland development; positive regulation of neuron apoptosis; kidney development; B cell apoptosis; B cell homeostasis; positive regulation of protein homooligomerization; tube formation; odontog
BCL2L12apoptotic process
BCL2L13regulation of apoptotic process; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process
BCL6Bnegative regulation of transcription from RNA polymerase II promoter
BCL7Anegative regulation of transcription, DNA-dependent
BCL9regulation of transforming growth factor beta receptor signaling pathway; Wnt receptor signaling pathway
BCL9Lnegative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; regulation of cell morphogenesis; positive regulation of epithelial to mesenchymal transition; regulation of transcription, DNA-dependent
BCLAF1induction of apoptosis; positive regulation of apoptotic process; regulation of DNA-dependent transcription in response to stress; positive regulation of transcription initiation, DNA-dependent; positive regulation of response to DNA damage stimulus; negative regulation of transcription, DNA-dependent; positive regulation of intrinsic apoptotic signaling pathway
BCO2retinal metabolic process; carotene metabolic process; retinoic acid metabolic process
BCORheart development; negative regulation of histone H3-K36 methylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of bone mineralization; histone H2A monoubiquitination; odontogenesis; negative regulation of transcription, DNA-dependent; negative regulation of histone H3-K4 methylation; palate development; specification of axis polarity; negative regulation of tooth mineralization; chromatin modification
BCORL1regulation of transcription, DNA-dependent; chromatin modification
BCRinner ear morphogenesis; protein phosphorylation; signal transduction; small GTPase mediated signal transduction; brain development; actin cytoskeleton organization; negative regulation of cell migration; response to lipopolysaccharide; regulation of Rho protein signal transduction; negative regulation of neutrophil degranulation; positive regulation of GTPase activity; negative regulation of inflammatory response; positive regulation of phagocytosis; neuromuscular process controlling balance; regulation of small GTPase mediated signal transduction; regulation of cell cycle
BCS1Lmitochondrion organization; mitochondrial respiratory chain complex I assembly; mitochondrial respiratory chain complex IV assembly; mitochondrial respiratory chain complex III assembly
BDKRB1response to lipopolysaccharide; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of blood pressure; negative regulation of cell growth; negative regulation of protein phosphorylation; positive regulation of leukocyte migration; inflammatory response; elevation of cytosolic calcium ion concentration; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; cell migration; sensory perception of pain
BDKRB2regulation of vasoconstriction; smooth muscle contraction; inflammatory response; cell surface receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; arachidonic acid secretion; regulation of vascular permeability; blood circulation
BDNFinner ear development; feeding behavior; regulation of synaptic plasticity; regulation of retinal cell programmed cell death; positive regulation of neuron differentiation; negative regulation of neuron apoptosis; fear response; response to drug; nerve development; ureteric bud development; anti-apoptosis; nervous system development; negative regulation of neuroblast proliferation; axon guidance; axon target recognition; mechanoreceptor differentiation; regulation of metabolic process; dendrite development; glutamate secretion; neuron recognition; learning or memory
BDP1regulation of transcription, DNA-dependent; gene expression; transcription from RNA polymerase III promoter
BECN1anti-apoptosis; positive regulation of macroautophagy; response to virus; negative regulation of cell proliferation; cell cycle; cellular defense response; autophagy; cytokinesis; autophagic vacuole assembly
BEND2-
BEND3-
BEND5-
BEND6-
BEST1ion transport; transepithelial chloride transport; visual perception; chloride transport; response to stimulus
BEST2chloride transport; sensory perception of smell; membrane depolarization; ion transport
BEST3ion transmembrane transport; negative regulation of ion transport
BEST4ion transport
BEX5-
BFSP2cell maturation; response to stimulus; intermediate filament cytoskeleton organization; lens fiber cell development; visual perception
BHLHE40negative regulation of sequence-specific DNA binding transcription factor activity; entrainment of circadian clock by photoperiod; circadian regulation of gene expression; response to light stimulus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; regulation of neuronal synaptic plasticity
BHLHE41negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; circadian rhythm; cell proliferation; organ morphogenesis; negative regulation of myotube differentiation; negative regulation of transcription by competitive promoter binding; cell differentiation
BHMTcellular nitrogen compound metabolic process; methionine biosynthetic process; protein methylation; sulfur amino acid metabolic process; regulation of homocysteine metabolic process; small molecule metabolic process
BHMT2methionine biosynthetic process
BICC1multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway
BICD2transport; microtubule anchoring at microtubule organizing center; minus-end-directed organelle transport along microtubule
BIN1positive regulation of endocytosis; cell proliferation; muscle cell differentiation; positive regulation of GTPase activity; multicellular organismal development; interspecies interaction between organisms
BIN2-
BIRC2regulation of innate immune response; protein polyubiquitination; placenta development; apoptotic process; anti-apoptosis; cellular component disassembly involved in apoptosis; cell surface receptor signaling pathway; regulation of toll-like receptor signaling pathway; NIK/NF-kappaB cascade; regulation of RIG-I signaling pathway; regulation of cell proliferation; negative regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; proteasomal ubiquitin-dependent protein catabolic process; regulation of cysteine-type endopeptidase activity; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of cell cycle; regulation of inflammatory response; regulation of cell differentiation
BIRC3regulation of RIG-I signaling pathway; regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; NIK/NF-kappaB cascade; regulation of toll-like receptor signaling pathway; cell surface receptor signaling pathway; anti-apoptosis; regulation of innate immune response; regulation of inflammatory response; regulation of nucleotide-binding oligomerization domain containing signaling pathway; regulation of cysteine-type endopeptidase activity
BIRC5G2/M transition of mitotic cell cycle; establishment of chromosome localization; cell division; positive regulation of mitotic cell cycle; negative regulation of transcription, DNA-dependent; regulation of apoptotic process; cytokinesis; protein phosphorylation; anti-apoptosis; chromosome segregation; mitosis; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of cell proliferation; protein complex localization; positive regulation of exit from mitosis; spindle checkpoint
BLKpositive regulation of insulin secretion; B cell receptor signaling pathway; intracellular protein kinase cascade
BLMnegative regulation of cell division; chromosome organization; protein oligomerization; regulation of binding; replication fork protection; positive regulation of alpha-beta T cell proliferation; alpha-beta T cell differentiation; negative regulation of mitotic recombination; negative regulation of DNA recombination; positive regulation of transcription, DNA-dependent; G2/M transition DNA damage checkpoint; regulation of cyclin-dependent protein kinase activity; G2 phase of mitotic cell cycle; telomere maintenance; double-strand break repair via homologous recombination; DNA strand renaturation; ATP catabolic process; DNA replication; response to DNA damage stimulus; response to X-ray; replication fork processing; cellular metabolic process; DNA recombination; DNA repair
BLNKintracellular signal transduction; inflammatory response; humoral immune response; transmembrane receptor protein tyrosine kinase signaling pathway; B cell differentiation
BLOC1S6-
BLZF1Golgi to plasma membrane protein transport; protein transport; cell proliferation; Golgi organization; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of cell growth; vesicle-mediated transport
BMFactivation of pro-apoptotic gene products; induction of apoptosis by intracellular signals; apoptotic process; regulation of apoptotic process; positive regulation of release of cytochrome c from mitochondria; positive regulation of protein homooligomerization
BMP1positive regulation of cartilage development; small molecule metabolic process; lipoprotein metabolic process; cell differentiation; multicellular organismal development; lipid metabolic process; proteolysis; ossification; cartilage condensation; skeletal system development
BMP10ventricular cardiac muscle cell development; adult heart development; positive regulation of pathway-restricted SMAD protein phosphorylation; negative regulation of cell growth; negative regulation of cell migration; BMP signaling pathway; activin receptor signaling pathway; growth; sarcomere organization; positive regulation of transcription, DNA-dependent; atrial cardiac muscle tissue morphogenesis; Notch signaling pathway; multicellular organismal development; negative regulation of endothelial cell migration; positive regulation of cardiac muscle hypertrophy; negative regulation of cardiac muscle hypertrophy; ventricular cardiac muscle tissue morphogenesis; cardiac muscle cell proliferation; positive regulation of cardiac muscle cell proliferation; pathway-restricted SMAD protein phosphorylation; heart trabecula formation
BMP15granulosa cell development; female gamete generation; ovarian follicle development
BMP2positive regulation of apoptotic process; cellular response to growth factor stimulus; cellular response to organic cyclic compound; mesenchymal cell proliferation involved in ureteric bud development; positive regulation of ossification; positive regulation of osteoblast differentiation; positive regulation of neuron differentiation; positive regulation of fat cell differentiation; cell fate commitment; positive regulation of cartilage development; ovulation cycle; regulation of odontogenesis of dentin-containing tooth; positive regulation of odontogenesis; odontogenesis of dentin-containing tooth; bone mineralization involved in bone maturation; embryonic heart tube anterior/posterior pattern specification; cardiac cell differentiation; positive regulation of osteoblast proliferation; cardiac muscle tissue morphogenesis; negative regulation of cell cycle; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA po
BMP2Kregulation of bone mineralization; regulation of catalytic activity
BMP4negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; negative regulation of phosphorylation; monocyte differentiation; macrophage differentiation; positive regulation of bone mineralization; BMP signaling pathway; positive regulation of BMP signaling pathway; positive regulation of collagen biosynthetic process; negative regulation of T cell differentiation in thymus; negative regulation of immature T cell proliferation in thymus; protein localization to nucleus; tendon cell differentiation; deltoid tuberosity development; growth; telencephalon development; odontogenesis; positive regulation of apoptotic process; negative regulation of apoptotic process; steroid hormone mediated signaling pathway; negative regulation of MAP kinase activity; negative regulation of myoblast differentiation; positive regulation of osteoblast differentiation; positive regulation of ossification; negative regulation of cell cycle; negative regulation of mitosis; negative regulat
BMP5cell differentiation; cartilage development; growth; male genitalia development; pattern specification process; ossification; skeletal system development
BMP6positive regulation of transcription from RNA polymerase II promoter; SMAD protein signal transduction; cartilage development; positive regulation of osteoblast differentiation; positive regulation of neuron differentiation; positive regulation of endothelial cell differentiation; growth; positive regulation of aldosterone biosynthetic process; male genitalia development; BMP signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of bone mineralization; skeletal system development; eye development; kidney development; positive regulation of endothelial cell proliferation; endochondral ossification; inflammatory response; immune response; multicellular organismal development
BMP7negative regulation of Notch signaling pathway; negative regulation of neurogenesis; neuron projection morphogenesis; mesenchymal cell differentiation; cartilage development; branching morphogenesis of a tube; anatomical structure formation involved in morphogenesis; embryonic camera-type eye morphogenesis; cell development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of mitosis; negative regulation of cell cycle; positive regulation of apoptotic process; embryonic skeletal joint morphogenesis; pathway-restricted SMAD protein phosphorylation; SMAD protein signal transduction; branching involved in salivary gland morphogenesis; mesenchyme development; negative regulation of cell death; negative regulation of prostatic bud formation; regulation of branching involved in prostate gland morphogenesis; monocyte aggregation; cellular response to hypoxia; negative reg
BMPERnegative regulation of BMP signaling pathway; regulation of endothelial cell migration; blood vessel endothelial cell proliferation involved in sprouting angiogenesis; ureteric bud development; endothelial cell activation; regulation of pathway-restricted SMAD protein phosphorylation; positive regulation of ERK1 and ERK2 cascade
BMPR1Bovarian cumulus expansion; positive regulation of osteoblast differentiation; positive regulation of cell differentiation; ovulation cycle; limb morphogenesis; BMP signaling pathway; positive regulation of bone mineralization; transmembrane receptor protein serine/threonine kinase signaling pathway; protein phosphorylation; eye development; cartilage condensation; skeletal system development
BMPR2positive regulation of pathway-restricted SMAD protein phosphorylation; negative regulation of cell growth; regulation of lung blood pressure; positive regulation of bone mineralization; BMP signaling pathway; positive regulation of BMP signaling pathway; regulation of cell proliferation; positive regulation of osteoblast differentiation; negative regulation of vasoconstriction; retina development in camera-type eye; lung alveolus development; vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; anterior/posterior pattern specification; positive regulation of epithelial cell migration; mesoderm formation; positive regulation of endothelial cell proliferation; negative regulation of systemic arterial blood pressure; transmembrane receptor protein serine/threonine kinase signaling pathway; brain development; cellular response to starvation; transcription from RNA polymerase II promoter
BMXintracellular signal transduction; protein autophosphorylation; mesoderm development; signal transduction; cell adhesion; response to stress; apoptotic process; protein phosphorylation; cellular component disassembly involved in apoptosis
BNC1epidermis development; positive regulation of cell proliferation; regulation of transcription, DNA-dependent
BNC2regulation of transcription, DNA-dependent
BNIP3Linduction of apoptosis; negative regulation of survival gene product expression; mitochondrial protein catabolic process; negative regulation of apoptotic process; interspecies interaction between organisms; defense response to virus
BNIPLapoptotic process; regulation of growth rate; negative regulation of cell proliferation; induction of apoptosis
BOCpositive regulation of myoblast differentiation; positive regulation of muscle cell differentiation; muscle cell differentiation; cell adhesion
BOKinduction of apoptosis; apoptotic process; signal transduction by p53 class mediator resulting in induction of apoptosis; oligodendrocyte differentiation; male gonad development; cell proliferation; brain development; activation of cysteine-type endopeptidase activity involved in apoptotic process
BOLLpositive regulation of translational initiation; cell differentiation; spermatogenesis; multicellular organismal development; meiosis; regulation of translation
BORAregulation of mitosis; cell division; regulation of mitotic spindle organization; regulation of protein localization; cell cycle
BORCS5-
BPGMcarbohydrate metabolic process; glycolysis; respiratory gaseous exchange; erythrocyte development
BPHLcellular amino acid metabolic process; response to toxin
BPIFA1innate immune response
BPIFA3-
BPIFB2-
BPIFB4-
BPIFB6-
BPIFC-
BPTFnegative regulation of transcription from RNA polymerase II promoter; chromatin remodeling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; brain development; positive regulation of transcription, DNA-dependent
BRAFnerve growth factor receptor signaling pathway; activation of MAPKK activity; protein phosphorylation; anti-apoptosis; small GTPase mediated signal transduction; synaptic transmission; fibroblast growth factor receptor signaling pathway; organ morphogenesis; positive regulation of peptidyl-serine phosphorylation; positive regulation of ERK1 and ERK2 cascade; response to cAMP; negative regulation of neuron apoptosis; negative regulation of apoptotic process; positive regulation of gene expression; response to peptide hormone stimulus
BRAPprotein ubiquitination; MAPK cascade; Ras protein signal transduction; negative regulation of signal transduction
BRAT1response to ionizing radiation
BRCA1positive regulation of histone H4-K20 methylation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of centriole replication; positive regulation of histone H3-K4 methylation; negative regulation of histone H3-K4 methylation; negative regulation of histone H3-K9 methylation; positive regulation of histone H3-K9 methylation; protein autoubiquitination; positive regulation of cell cycle arrest; protein K6-linked ubiquitination; regulation of cell motility; positive regulation of histone H3-K9 acetylation; positive regulation of histone H4-K16 acetylation; cellular response to indole-3-methanol; regulation of transcription from RNA polymerase II promoter; response to nutrient; brain development; centrosome cycle; chromosome segregation; cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; response to DNA damage stimulus; apoptotic process; regulatio
BRCA2DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; multicellular organism growth; negative regulation of mammary gland epithelial cell proliferation; cell cycle cytokinesis; regulation of cytokinesis; response to estradiol stimulus; homologous chromosome orientation involved in meiotic metaphase I plate congression; mammary gland development; hemopoiesis; chordate embryonic development; histone H3 acetylation; histone H4 acetylation; positive regulation of transcription, DNA-dependent; positive regulation of mitotic cell cycle; replication fork protection; inner cell mass cell proliferation; chromosome organization; centrosome duplication; response to UV-C; double-strand break repair via homologous recombination; oocyte maturation; DNA repair; nucleotide-excision repair; double-strand break repair; DNA recombination; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; cell cycle; regulation of S phase
BRD1chromatin modification; histone H3 acetylation
BRD3-
BRD4regulation of transcription involved in G1 phase of mitotic cell cycle; positive regulation of DNA binding; histone H4-K12 acetylation; histone H3-K14 acetylation; interspecies interaction between organisms; positive regulation of transcription elongation from RNA polymerase II promoter; inner cell mass cell proliferation; positive regulation of G2/M transition of mitotic cell cycle; protein phosphorylation; chromosome segregation
BRD7negative regulation of G1/S transition of mitotic cell cycle; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of histone acetylation; regulation of transcription from RNA polymerase II promoter; cell cycle; Wnt receptor signaling pathway; negative regulation of cell proliferation
BRD8regulation of growth; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; signal transduction; cell surface receptor signaling pathway; chromatin modification; histone H4 acetylation; histone H2A acetylation
BRDTchromatin remodeling; regulation of transcription, DNA-dependent
BRF2transcription initiation, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase III promoter; gene expression
BRICD5-
BRINP1negative regulation of cell cycle; cell death; cell cycle arrest
BRINP2nervous system development; negative regulation of cell cycle
BRINP3negative regulation of cell cycle; nervous system development
BRIP1regulation of transcription from RNA polymerase II promoter; double-strand break repair; nucleobase-containing compound metabolic process; DNA damage checkpoint
BRIX1ribosome biogenesis
BRMS1negative regulation of anti-apoptosis; negative regulation of transcription, DNA-dependent; positive regulation of protein deacetylation; positive regulation of anoikis; apoptotic process; negative regulation of NF-kappaB transcription factor activity
BRPF1positive regulation of transcription, DNA-dependent; chromatin modification; histone H3 acetylation
BRPF3platelet degranulation; blood coagulation; chromatin modification; platelet activation; histone H3 acetylation
BRS3bombesin receptor signaling pathway; glucose metabolic process; regulation of blood pressure; adult feeding behavior
BRSK1axonogenesis; cell cycle; response to UV; response to DNA damage stimulus; protein phosphorylation; nervous system development; response to ionizing radiation; establishment of cell polarity; neuron differentiation; G2/M transition DNA damage checkpoint; centrosome duplication; neurotransmitter secretion
BRWD1cytoskeleton organization; regulation of transcription from RNA polymerase II promoter; regulation of cell shape
BRWD3regulation of cell shape; cytoskeleton organization
BSCL2cell death
BSDC1-
BSGpyruvate metabolic process; cell surface receptor signaling pathway; response to cAMP; leukocyte migration; decidualization; response to mercury ion; embryo implantation; small molecule metabolic process; response to peptide hormone stimulus; odontogenesis of dentin-containing tooth; lactate transmembrane transport; blood coagulation
BSNsynaptic transmission
BSNDchloride transport
BSPRYcalcium ion transport; ion transport
BST1multicellular organismal development; humoral immune response
BST2defense response to virus; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; B cell activation; cell proliferation; humoral immune response; multicellular organismal development; cell-cell signaling; signal transduction
BTAF1negative regulation of transcription, DNA-dependent
BTBD10-
BTBD11-
BTBD16-
BTBD17-
BTBD2-
BTBD3-
BTBD7-
BTBD8-
BTBD9cell adhesion
BTF3L4-
BTG3negative regulation of cell proliferation; negative regulation of mitotic cell cycle
BTG4neuron differentiation; negative regulation of mitotic cell cycle; negative regulation of cell proliferation; cell cycle arrest
BTN1A1negative regulation of cytokine secretion; negative regulation of activated T cell proliferation; negative regulation of cellular metabolic process
BTN2A1lipid metabolic process
BTN3A1lipid metabolic process
BTN3A2-
BTNL9-
BTRCpositive regulation of transcription, DNA-dependent; regulation of proteasomal protein catabolic process; cellular response to organic cyclic compound; protein catabolic process; negative regulation of sequence-specific DNA binding transcription factor activity; interspecies interaction between organisms; positive regulation of proteolysis; negative regulation of smoothened signaling pathway; negative regulation of transcription, DNA-dependent; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of circadian rhythm; mammary gland epithelial cell proliferation; protein destabilization; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; branching involved in mammary gland duct morphogenesis; protein ubiquitination; Wnt receptor signaling pathway; viral reprod
BUB1interspecies interaction between organisms; spindle assembly checkpoint; regulation of chromosome segregation; cell division; embryo development; cell proliferation; mitotic cell cycle spindle assembly checkpoint; mitotic cell cycle checkpoint; regulation of sister chromatid cohesion; apoptotic process; protein phosphorylation; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle
BUB1Bcell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell division; protein localization to kinetochore; cell cycle checkpoint; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; protein phosphorylation; apoptotic process; spindle organization; mitosis; mitotic metaphase/anaphase transition; mitotic cell cycle checkpoint; mitotic cell cycle spindle assembly checkpoint; cell proliferation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; phosphatidylinositol-mediated signaling
BVESregulation of Cdc42 GTPase activity; muscle organ development; multicellular organismal development; cell adhesion; positive regulation of receptor recycling; substrate adhesion-dependent cell spreading; regulation of Rac GTPase activity; vesicle-mediated transport; epithelial cell-cell adhesion; regulation of cell shape; positive regulation of locomotion
BYSLribosome biogenesis; female pregnancy; cell adhesion
BZRAP1-
C10orf10-
C10orf120-
C10orf2DNA unwinding involved in replication; transcription from mitochondrial promoter; cell death; protein hexamerization; protein homooligomerization; mitochondrial DNA replication; DNA replication
C10orf35-
C10orf76-
C10orf82-
C10orf88-
C10orf90mitotic cell cycle G2/M transition DNA damage checkpoint; response to DNA damage stimulus; protein stabilization; negative regulation of cell growth; response to ionizing radiation; response to UV
C11orf40-
C11orf53-
C11orf65-
C11orf70-
C11orf84-
C11orf87-
C12orf10pigmentation
C12orf29-
C12orf4-
C12orf40-
C12orf50-
C12orf60-
C12orf65translational termination
C14orf105-
C14orf159-
C14orf180-
C14orf2-
C14orf28-
C14orf37-
C14orf39regulation of sequence-specific DNA binding transcription factor activity; multicellular organismal development
C14orf79-
C14orf93-
C15orf32-
C15orf39-
C15orf40-
C15orf54-
C15orf59-
C16orf45-
C16orf46-
C16orf59-
C16orf62-
C16orf71-
C16orf78-
C16orf91-
C17orf47-
C17orf53-
C17orf74-
C17orf80-
C17orf98-
C18orf25-
C19orf18-
C19orf44-
C19orf45-
C19orf53-
C19orf70-
C19orf73-
C1Dnegative regulation of transcription, DNA-dependent; maturation of 5.8S rRNA; apoptotic process
C1GALT1C1O-glycan processing; post-translational protein modification; cellular protein metabolic process
C1orf100-
C1orf101-
C1orf106-
C1orf111-
C1orf116-
C1orf127-
C1orf131-
C1orf141-
C1orf168-
C1orf189-
C1orf21-
C1orf216-
C1orf222-
C1orf50-
C1orf64-
C1orf87-
C1orf95-
C1QAcomplement activation, classical pathway; innate immune response; cell-cell signaling; complement activation
C1QBaging; complement activation, classical pathway; complement activation; brain development; response to glucocorticoid stimulus; innate immune response; response to organic substance
C1QBPinterspecies interaction between organisms; blood coagulation, intrinsic pathway; blood coagulation; immune response
C1QCnegative regulation of granulocyte differentiation; complement activation, classical pathway; immune response; complement activation; negative regulation of macrophage differentiation; innate immune response
C1QL3-
C1QL4-
C1QTNF1protein homooligomerization
C1QTNF3negative regulation of gluconeogenesis
C1QTNF4-
C1QTNF6-
C1Scomplement activation, classical pathway; glial cell differentiation; innate immune response; response to cAMP; complement activation; proteolysis
C20orf141-
C20orf194-
C20orf27-
C20orf96-
C21orf2cytoskeleton organization; regulation of cell shape
C21orf33-
C21orf91-
C22orf29-
C22orf31-
C22orf42-
C2CD2-
C2CD2L-
C2CD3-
C2CD4A-
C2CD5-
C2orf15-
C2orf16-
C2orf40cyclin catabolic process; G1 to G0 transition; cellular senescence
C2orf42-
C2orf44-
C2orf49embryonic morphogenesis
C2orf54-
C2orf57-
C2orf66-
C2orf70-
C2orf76-
C2orf83transport
C3immune response; regulation of immune response; positive regulation of phagocytosis; positive regulation of angiogenesis; innate immune response; positive regulation vascular endothelial growth factor production; G-protein coupled receptor signaling pathway; signal transduction; complement activation, classical pathway; complement activation, alternative pathway; complement activation; inflammatory response; positive regulation of activation of membrane attack complex; positive regulation of type IIa hypersensitivity
C3AR1chemotaxis; positive regulation of neutrophil chemotaxis; complement receptor mediated signaling pathway; tolerance induction to nonself antigen; inflammatory response; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; blood circulation; regulation of blood pressure; positive regulation vascular endothelial growth factor production; positive regulation of macrophage chemotaxis; positive regulation of cell migration; positive regulation of angiogenesis
C3orf14-
C3orf17-
C3orf20-
C3orf22-
C3orf30-
C3orf58-
C3orf62-
C3orf67-
C3orf70-
C4orf17-
C4orf22-
C4orf26-
C5induction of apoptosis; cellular calcium ion homeostasis; leukocyte migration involved in inflammatory response; in utero embryonic development; chemotaxis; response to stress; inflammatory response; activation of MAPK activity; complement activation, alternative pathway; negative regulation of norepinephrine secretion; negative regulation of macrophage chemotaxis; cytolysis; negative regulation of dopamine secretion; glucose homeostasis; innate immune response; positive regulation of angiogenesis; positive regulation of chemotaxis; positive regulation of chemokine secretion; complement activation; positive regulation vascular endothelial growth factor production; G-protein coupled receptor signaling pathway; cell surface receptor signaling pathway; complement activation, classical pathway
C5AR2-
C5orf15-
C5orf22-
C5orf28-
C5orf42-
C5orf51-
C6positive regulation of angiogenesis; innate immune response; cytolysis; complement activation, classical pathway; complement activation; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; positive regulation of activation of membrane attack complex; in utero embryonic development
C6orf106-
C6orf118-
C6orf201-
C6orf203-
C6orf58-
C7orf25-
C7orf34-
C7orf43-
C7orf50-
C7orf62-
C8Aimmune response; innate immune response; cytolysis; complement activation, classical pathway; complement activation, alternative pathway; complement activation
C8Bimmune response; complement activation; complement activation, alternative pathway; complement activation, classical pathway; cytolysis; innate immune response
C8orf31-
C8orf33-
C8orf34signal transduction
C8orf44-
C9activation of cysteine-type endopeptidase activity involved in apoptotic process; innate immune response; hemolysis by symbiont of host erythrocytes; cytolysis; blood coagulation; complement activation, classical pathway; complement activation, alternative pathway; induction of apoptosis
C9orf116-
C9orf131-
C9orf135-
C9orf3proteolysis; leukotriene biosynthetic process
C9orf43-
C9orf47-
C9orf64-
C9orf72cell death
C9orf78-
C9orf84-
C9orf85-
C9orf9-
C9orf91-
CA1one-carbon metabolic process
CA10brain development
CA11-
CA12one-carbon metabolic process
CA14-
CA2response to stress; kidney development; morphogenesis of an epithelium; one-carbon metabolic process; response to pH; response to organic substance; response to zinc ion; positive regulation of cellular pH reduction; odontogenesis of dentin-containing tooth; carbon dioxide transport; response to estrogen stimulus; positive regulation of osteoclast differentiation; positive regulation of bone resorption; secretion
CA3one-carbon metabolic process; response to oxidative stress
CA5Bone-carbon metabolic process; metabolic process
CA9secretion; morphogenesis of an epithelium; one-carbon metabolic process
CAAP1apoptotic process
CAB39protein heterooligomerization; positive regulation of protein phosphorylation; cell cycle arrest; insulin receptor signaling pathway; regulation of fatty acid oxidation
CABIN1cell surface receptor signaling pathway; chromatin modification; negative regulation of cell death
CABLES1nervous system development; blood coagulation; regulation of cell division; regulation of cell cycle
CABP1negative regulation of catalytic activity
CABP4phototransduction; visual perception; signal transduction; photoreceptor cell morphogenesis; retinal cone cell development; retinal bipolar neuron differentiation
CABP7-
CACFD1synaptic vesicle endocytosis
CACHD1calcium ion transport; ion transport
CACNA1Daxon guidance; small molecule metabolic process; regulation of insulin secretion; regulation of calcium ion transport via voltage-gated calcium channel activity; transmembrane transport; energy reserve metabolic process; ion transport; calcium ion transport
CACNA1Fregulation of calcium ion transport via voltage-gated calcium channel activity; cellular calcium ion homeostasis; axon guidance; visual perception; dendrite morphogenesis; response to stimulus; detection of light stimulus involved in visual perception; transmembrane transport; retina development in camera-type eye; ion transport
CACNA1Smuscle cell development; transmembrane transport; regulation of calcium ion transport via voltage-gated calcium channel activity; skeletal muscle adaptation; neuromuscular junction development; myoblast fusion; axon guidance; striated muscle contraction; muscle contraction; calcium ion transport; ion transport; endoplasmic reticulum organization; extraocular skeletal muscle development; skeletal system development
CACNA2D1ion transport; calcium ion transport; regulation of calcium ion transport via voltage-gated calcium channel activity
CACNA2D2regulation of multicellular organism growth; neuromuscular junction development; positive regulation of organ growth; muscle fiber development; regulation of insulin secretion; small molecule metabolic process; rhythmic synaptic transmission; ion transport; energy reserve metabolic process
CACNB2transport; ion transport; calcium ion transport; synaptic transmission; calcium ion transmembrane transport; regulation of calcium ion transport via voltage-gated calcium channel activity; visual perception; neuromuscular junction development; axon guidance
CACNG3calcium ion transport; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; regulation of calcium ion transport via voltage-gated calcium channel activity; synaptic transmission; ion transport
CACNG4membrane depolarization; regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; synaptic transmission; ion transport; transport
CACNG5regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; transport; ion transmembrane transport
CACNG8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; regulation of calcium ion transport via voltage-gated calcium channel activity; calcium ion transport; ion transport; synaptic transmission
CACUL1-
CADresponse to caffeine; nitrogen compound metabolic process; glutamine catabolic process; glutamine metabolic process; cellular amino acid metabolic process; pyrimidine nucleotide biosynthetic process; 'de novo' pyrimidine base biosynthetic process; pyrimidine base metabolic process; female pregnancy; embryo development; response to amine stimulus; drug metabolic process; peptidyl-threonine phosphorylation; organ regeneration; response to testosterone stimulus; small molecule metabolic process; pyrimidine nucleoside biosynthetic process; protein autophosphorylation; nucleobase-containing small molecule metabolic process; carbamoyl phosphate biosynthetic process
CADM1detection of stimulus; activated T cell proliferation; positive regulation of cytokine secretion; positive regulation of natural killer cell mediated cytotoxicity; cell-cell junction organization; susceptibility to natural killer cell mediated cytotoxicity; adherens junction organization; cell junction assembly; cell differentiation; cell recognition; spermatogenesis; multicellular organismal development; heterophilic cell-cell adhesion; homophilic cell adhesion; cell adhesion; apoptotic process; T cell mediated cytotoxicity
CADPScatecholamine secretion; positive regulation of calcium ion-dependent exocytosis; synaptic vesicle priming; exocytosis; protein transport; vesicle organization
CALB1locomotory behavior; learning or memory; retina layer formation; metanephric ureteric bud development; regulation of synaptic plasticity; retina development in camera-type eye; metanephric collecting duct development; metanephric distal convoluted tubule development; metanephric connecting tubule development
CALCAcell-cell signaling; neuropeptide signaling pathway; elevation of cytosolic calcium ion concentration; activation of adenylate cyclase activity; activation of adenylate cyclase activity by G-protein signaling pathway; leukocyte cell-cell adhesion; positive regulation of macrophage differentiation; cellular calcium ion homeostasis; embryo implantation; aging; feeding behavior; regulation of blood pressure; response to heat; negative regulation of calcium ion transport into cytosol; negative regulation of ossification; positive regulation of cAMP biosynthetic process; receptor internalization; negative regulation of neurological system process; activation of protein kinase activity; positive regulation of interleukin-1 alpha production; positive regulation of interleukin-8 production; endothelial cell migration; monocyte chemotaxis; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; cytosolic calcium ion homeostasis; detection of temperature stimulu
CALCOCO1Wnt receptor signaling pathway; positive regulation of transcription, DNA-dependent; intracellular steroid hormone receptor signaling pathway; signal transduction; transcription, DNA-dependent
CALCOCO2response to interferon-gamma; viral reproduction
CALCRactivation of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity; activation of phospholipase C activity; elevation of cytosolic calcium ion concentration; protein transport; positive regulation of cAMP biosynthetic process; receptor internalization; positive regulation of adenylate cyclase activity; response to glucocorticoid stimulus; protein localization in plasma membrane
CALCRLG-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of smooth muscle cell proliferation; regulation of muscle contraction; calcium ion transport; negative regulation of inflammatory response; cellular response to sucrose stimulus; angiogenesis; positive regulation of cAMP biosynthetic process; protein transport; cAMP biosynthetic process; heart development; activation of adenylate cyclase activity by G-protein signaling pathway; receptor internalization
CALD1cellular component movement; muscle contraction; positive regulation of protein binding; actin filament bundle assembly
CALHM1ion transport
CALHM2-
CALML3-
CALML5epidermis development; signal transduction
CALML6-
CALN1-
CALRpositive regulation of cell proliferation; spermatogenesis; cell cycle arrest; activation of signaling protein activity involved in unfolded protein response; cellular calcium ion homeostasis; glucocorticoid receptor signaling pathway; protein export from nucleus; positive regulation of gene expression; negative regulation of translation; protein N-linked glycosylation via asparagine; protein maturation by protein folding; cortical actin cytoskeleton organization; endoplasmic reticulum unfolded protein response; response to estradiol stimulus; negative regulation of intracellular steroid hormone receptor signaling pathway; response to testosterone stimulus; protein localization to nucleus; regulation of meiosis; response to drug; antigen processing and presentation of exogenous peptide antigen via MHC class I; cellular senescence; positive regulation of cell cycle; cellular response to organic substance; cellular response to lithium ion; cardiac muscle cell differentiation; sequestering of calcium ion; protei
CALR3cell differentiation; spermatogenesis; protein folding
CALUplatelet activation; blood coagulation; platelet degranulation
CAMK1Dpositive regulation of neuron projection development; positive regulation of neutrophil chemotaxis; nervous system development; regulation of granulocyte chemotaxis; positive regulation of respiratory burst; regulation of dendrite development; inflammatory response; positive regulation of phagocytosis; regulation of apoptotic process; positive regulation of CREB transcription factor activity
CAMK1G-
CAMK2Ainterferon-gamma-mediated signaling pathway; positive regulation of NF-kappaB transcription factor activity; cytokine-mediated signaling pathway; synaptic transmission; protein phosphorylation
CAMK2Bpeptidyl-serine phosphorylation; regulation of calcium ion transport; regulation of skeletal muscle adaptation; positive regulation of neuron projection development; nervous system development; multicellular organismal development; synaptic transmission; signal transduction; protein phosphorylation; positive regulation of synapse maturation; cytokine-mediated signaling pathway; cell differentiation; induction of apoptosis in response to chemical stimulus; regulation of synaptic transmission, cholinergic; response to cadmium ion; protein autophosphorylation; regulation of long-term neuronal synaptic plasticity; neuromuscular process controlling balance; regulation of synapse structural plasticity; activation of meiosis involved in egg activation; regulation of dendritic spine development; positive regulation of dendritic spine morphogenesis; interferon-gamma-mediated signaling pathway; inhibitory G-protein coupled receptor phosphorylation; G1/S transition of mitotic cell cycle
CAMK2Dcardiac muscle contraction; protein autophosphorylation; cytokine-mediated signaling pathway; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; positive regulation of cardiac muscle hypertrophy; regulation of heart contraction; synaptic transmission; calcium ion transport; protein phosphorylation; regulation of cell growth; G1/S transition of mitotic cell cycle; regulation of ryanodine-sensitive calcium-release channel activity; regulation of cellular localization; interferon-gamma-mediated signaling pathway
CAMK2Gmulticellular organismal development; interferon-gamma-mediated signaling pathway; regulation of calcium ion transport; cell differentiation; insulin secretion; cytokine-mediated signaling pathway; regulation of skeletal muscle adaptation; nervous system development; synaptic transmission; protein phosphorylation
CAMK2N1negative regulation of phosphorylation; negative regulation of catalytic activity
CAMK4myeloid dendritic cell cytokine production; protein phosphorylation; inflammatory response; signal transduction; epidermal growth factor receptor signaling pathway; synaptic transmission; activation of phospholipase C activity; fibroblast growth factor receptor signaling pathway; regulation of T cell differentiation in thymus; myeloid dendritic cell differentiation; regulation of osteoclast differentiation; positive regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; long-term memory
CAMKK1synaptic transmission
CAMKK2protein autophosphorylation; positive regulation of transcription, DNA-dependent; regulation of protein kinase activity; calcium-mediated signaling; protein phosphorylation; MAPK cascade
CAMKV-
CAMLGreceptor recycling; defense response; signal transduction; epidermal growth factor receptor signaling pathway
CAMSAP3negative regulation of phosphatase activity; microtubule anchoring; epithelial cell-cell adhesion; regulation of microtubule cytoskeleton organization; zonula adherens maintenance
CAMTA1regulation of transcription, DNA-dependent
CAMTA2positive regulation of transcription from RNA polymerase II promoter; cardiac muscle hypertrophy in response to stress; regulation of transcription from RNA polymerase II promoter
CAND1regulation of transcription, DNA-dependent; protein ubiquitination; negative regulation of catalytic activity; cell differentiation
CAND2positive regulation of transcription, DNA-dependent
CAPGprotein complex assembly; cell projection assembly; barbed-end actin filament capping
CAPN12proteolysis
CAPN15-
CAPN3sarcomere organization; regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptotic process; response to drug; negative regulation of protein sumoylation; myofibril assembly; positive regulation of proteolysis; response to muscle activity; cellular response to calcium ion; protein localization in membrane; cellular response to salt stress; muscle structure development; response to calcium ion; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of NF-kappaB transcription factor activity; regulation of catalytic activity; muscle cell homeostasis; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; muscle organ development; signal transduction; apoptotic process; proteolysis; protein complex assembly; autolysis; positive regulation of satellite cell activation involved in skeletal muscle regeneration
CAPN6regulation of cytoskeleton organization; microtubule bundle formation; proteolysis
CAPN7proteolysis
CAPRIN1negative regulation of translation; cell differentiation; positive regulation of dendrite morphogenesis; positive regulation of dendritic spine morphogenesis
CAPRIN2cell differentiation; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of dendritic spine morphogenesis; positive regulation of dendrite morphogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of cell growth; positive regulation of protein binding; positive regulation of peptidyl-serine phosphorylation; negative regulation of translation; regulation of growth
CAPS2-
CAPZA2actin filament capping; innate immune response; actin cytoskeleton organization; cellular component movement; blood coagulation; protein complex assembly
CAPZA3spermatid development; actin filament capping; actin cytoskeleton organization
CAPZBcellular component movement; cytoskeleton organization; blood coagulation; regulation of cell morphogenesis; cell projection organization; lamellipodium assembly; actin cytoskeleton organization; actin filament capping
CARD11positive regulation of cytokine production; positive regulation of NF-kappaB transcription factor activity; T cell receptor signaling pathway; regulation of immune response; regulation of T cell differentiation; regulation of B cell differentiation; positive regulation of interleukin-2 biosynthetic process; thymic T cell selection; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; positive regulation of T cell proliferation; T cell costimulation; positive regulation of B cell proliferation; signal transduction
CARD14positive regulation of protein phosphorylation; activation of NF-kappaB-inducing kinase activity; regulation of apoptotic process
CARD16regulation of apoptotic process
CARD6regulation of apoptotic process
CARD8activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of apoptotic process; positive regulation of interleukin-1 beta secretion; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade
CARF-
CARKD-
CARM1peptidyl-arginine N-methylation; regulation of growth plate cartilage chondrocyte proliferation; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; chromatin modification; histone methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; intracellular steroid hormone receptor signaling pathway; negative regulation of protein binding; regulation of intracellular estrogen receptor signaling pathway; histone H3-R2 methylation; histone H3-R17 methylation; endochondral bone morphogenesis; cellular lipid metabolic process; small molecule metabolic process; pathogenesis; interspecies interaction between organisms; positive regulation of fat cell differentiation; response to cAMP
CARNMT1-
CARSgene expression; cysteinyl-tRNA aminoacylation; tRNA aminoacylation for protein translation
CASC1-
CASC5chromosome segregation; M phase of mitotic cell cycle; mitotic prometaphase; spindle assembly checkpoint; mitotic cell cycle; cell division; CenH3-containing nucleosome assembly at centromere; negative regulation of phosphatase activity; acrosome assembly; nucleosome assembly; attachment of spindle microtubules to kinetochore
CASKnegative regulation of cellular response to growth factor stimulus; negative regulation of cell-matrix adhesion; cell adhesion; negative regulation of keratinocyte proliferation; negative regulation of wound healing
CASKIN1signal transduction
CASKIN2-
CASP1nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; signal transduction; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; proteolysis; regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; cellular response to mechanical stimulus; cellular response to organic substance
CASP10innate immune response; apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; induction of apoptosis by extracellular signals; induction of apoptosis; proteolysis
CASP2apoptotic signaling pathway; execution phase of apoptosis; cellular response to mechanical stimulus; nerve growth factor receptor signaling pathway; positive regulation of neuron apoptosis; positive regulation of apoptotic process; protein processing; induction of apoptosis by extracellular signals; aging; metabolic process; luteolysis; neural retina development; proteolysis; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; brain development
CASP3regulation of apoptotic process; response to UV; response to wounding; protein processing; keratinocyte differentiation; nuclear fragmentation involved in apoptotic nuclear change; negative regulation of B cell proliferation; response to tumor necrosis factor; negative regulation of phosphorylation; T cell homeostasis; negative regulation of apoptotic process; positive regulation of neuron apoptosis; cell fate commitment; negative regulation of cyclin-dependent protein kinase activity; negative regulation of activated T cell proliferation; nerve growth factor receptor signaling pathway; induction of apoptosis by oxidative stress; B cell homeostasis; release of cytochrome c from mitochondria; DNA fragmentation involved in apoptotic nuclear change; proteolysis; apoptotic process; induction of apoptosis; cellular component disassembly involved in apoptosis; response to DNA damage stimulus; heart development; sensory perception of sound; induction of apoptosis by extracellular signals; induction of apoptosis via
CASP5proteolysis; apoptotic process; regulation of apoptotic process; cellular response to mechanical stimulus
CASP7induction of apoptosis; positive regulation of neuron apoptosis; protein processing; response to UV; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; induction of apoptosis by intracellular signals; aging; heart development; cellular component disassembly involved in apoptosis; apoptotic process; proteolysis; release of cytochrome c from mitochondria
CASP8angiogenesis; neural tube formation; proteolysis; apoptotic process; cellular component disassembly involved in apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; extrinsic apoptotic signaling pathway; cellular response to mechanical stimulus; nucleotide-binding oligomerization domain containing signaling pathway; proteolysis involved in cellular protein catabolic process; protein heterooligomerization; response to antibiotic; response to ethanol; innate immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; response to lipopolysaccharide; heart development; metabolic process; induction of apoptosis by extracellular signals; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; response to cold; macrophage differentiation; response to cobalt ion; response to estradiol stimulus; response to tumo
CASP9regulation of apoptotic process; cellular response to dexamethasone stimulus; phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; positive regulation of neuron apoptosis; response to UV; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; fibroblast growth factor receptor signaling pathway; proteolysis; epidermal growth factor receptor signaling pathway; response to DNA damage stimulus; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; induction of apoptosis by intracellular signals
CASQ2striated muscle contraction; heart development
CASRcellular calcium ion homeostasis; calcium ion import; calcium-mediated signaling; anatomical structure morphogenesis; chemosensory behavior; G-protein coupled receptor signaling pathway; detection of calcium ion; ossification
CASS4cell adhesion
CASTnegative regulation of endopeptidase activity
CASZ1regulation of transcription, DNA-dependent
CATIP-
CATSPER1multicellular organismal development; sperm motility; transmembrane transport; cell differentiation; fusion of sperm to egg plasma membrane; spermatogenesis; ion transport; ciliary or flagellar motility
CATSPER3ion transport; multicellular organismal development; spermatogenesis; cell differentiation; transmembrane transport
CATSPER4transmembrane transport; cell differentiation; spermatogenesis; multicellular organismal development; ion transport
CATSPERBspermatogenesis; cell differentiation; multicellular organismal development
CATSPERD-
CATSPERGmulticellular organismal development; spermatogenesis; cell differentiation
CAV2vesicle docking; caveola assembly; positive regulation of dopamine receptor signaling pathway; protein oligomerization; skeletal muscle fiber development; vesicle organization; synaptic transmission; regulation of mitosis; endoplasmic reticulum organization; mitochondrion organization; vesicle fusion; negative regulation of endothelial cell proliferation; negative regulation of cell proliferation
CAV3T-tubule organization; regulation of membrane potential; glucose homeostasis; cholesterol homeostasis; negative regulation of MAP kinase activity; negative regulation of MAPK cascade; negative regulation of cell size; muscle cell homeostasis; negative regulation of nitric-oxide synthase activity; regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of cardiac muscle contraction; negative regulation of sarcomere organization; regulation of ventricular cardiomyocyte membrane repolarization; positive regulation of microtubule polymerization; membrane raft organization; negative regulation of protein kinase activity; triglyceride metabolic process; endocytosis; elevation of cytosolic calcium ion concentration; muscle organ development; protein localization; negative regulation of cardiac muscle hypertrophy; regulation of skeletal muscle contraction; cell growth; cell differentiation; regulation of heart contraction
CBARP-
CBFA2T2epithelial cell differentiation; positive regulation of neuron projection development; negative regulation of neuron projection development; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
CBFA2T3granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; cell proliferation
CBLpositive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of receptor-mediated endocytosis; negative regulation of apoptotic process; negative regulation of epidermal growth factor receptor signaling pathway; regulation of signaling; protein ubiquitination; regulation of transcription, DNA-dependent; cell surface receptor signaling pathway; fibroblast growth factor receptor signaling pathway; epidermal growth factor receptor signaling pathway
CBLBregulation of signaling; negative regulation of T cell receptor signaling pathway; negative regulation of alpha-beta T cell proliferation; positive regulation of protein catabolic process; T cell activation; intracellular signal transduction; response to hormone stimulus; response to gravity; cell surface receptor signaling pathway; signal transduction; immune response; NLS-bearing substrate import into nucleus; positive regulation of T cell anergy
CBLCnegative regulation of epidermal growth factor-activated receptor activity; regulation of signaling; negative regulation of epidermal growth factor receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; cell surface receptor signaling pathway; negative regulation of MAP kinase activity
CBLL1negative regulation of cell adhesion; positive regulation of endocytosis; cell-cell adhesion; protein ubiquitination; positive regulation of cell migration
CBLN1synaptic transmission; nervous system development
CBLN2-
CBR3phylloquinone catabolic process
CBR4fatty acid biosynthetic process; antibiotic metabolic process; protein homotetramerization
CBSregulation of blood vessel size; hydrogen sulfide biosynthetic process; cartilage development involved in endochondral bone morphogenesis; maternal process involved in female pregnancy; response to folic acid; homocysteine metabolic process; small molecule metabolic process; regulation of JUN kinase activity; homocysteine catabolic process; cellular nitrogen compound metabolic process; response to nutrient levels; regulation of cGMP metabolic process; L-cysteine catabolic process; cerebellum morphogenesis; sulfur amino acid metabolic process; endochondral ossification; blood vessel remodeling; cysteine biosynthetic process from serine; L-serine metabolic process; L-serine catabolic process; superoxide metabolic process; cellular amino acid biosynthetic process; cysteine biosynthetic process via cystathionine; transsulfuration
CBX2chromatin modification; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; development of primary sexual characteristics; cell differentiation
CBX5negative regulation of transcription, DNA-dependent; blood coagulation; interspecies interaction between organisms
CBX6regulation of transcription, DNA-dependent; chromatin modification; negative regulation of transcription from RNA polymerase II promoter
CBX8negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; chromatin modification; histone ubiquitination
CC2D1Aregulation of transcription, DNA-dependent; signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade
CC2D2B-
CCAR1RNA splicing; apoptotic process; cell cycle; regulation of transcription, DNA-dependent; nuclear mRNA splicing, via spliceosome; gene expression
CCAR2apoptotic process; positive regulation of apoptotic process; negative regulation of catalytic activity
CCBE1lymphangiogenesis; sprouting angiogenesis; multicellular organismal development; venous blood vessel morphogenesis
CCBL2cellular amino acid metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; biosynthetic process; tryptophan catabolic process; kynurenine metabolic process
CCDC102A-
CCDC102B-
CCDC110-
CCDC114-
CCDC115-
CCDC116-
CCDC117-
CCDC120-
CCDC125-
CCDC13-
CCDC130response to virus
CCDC138-
CCDC141-
CCDC148-
CCDC151-
CCDC153-
CCDC157-
CCDC158-
CCDC170-
CCDC171-
CCDC172-
CCDC178-
CCDC18-
CCDC181-
CCDC185-
CCDC186-
CCDC189-
CCDC191-
CCDC22-
CCDC27-
CCDC28B-
CCDC34-
CCDC36-
CCDC38-
CCDC40ciliary cell motility; flagellar cell motility; epithelial cilium movement involved in determination of left/right asymmetry; axonemal dynein complex assembly
CCDC47post-embryonic development; calcium ion homeostasis; embryo development; ER overload response
CCDC50-
CCDC62-
CCDC65-
CCDC68-
CCDC69-
CCDC7-
CCDC70-
CCDC73-
CCDC77-
CCDC80positive regulation of cell-substrate adhesion; extracellular matrix organization
CCDC81-
CCDC83-
CCDC86interspecies interaction between organisms
CCDC87-
CCDC88Aregulation of cell proliferation; microtubule cytoskeleton organization; regulation of protein phosphorylation; regulation of DNA replication; nervous system development; regulation of neuron projection development; cellular membrane organization; cell migration; lamellipodium assembly; TOR signaling cascade; activation of protein kinase B activity; regulation of actin cytoskeleton organization
CCDC88Bmicrotubule cytoskeleton organization
CCDC9-
CCDC91protein transport
CCDC93-
CCDC96-
CCDC97-
CCER1-
CCINcell differentiation; spermatogenesis; multicellular organismal development
CCKARregulation of hormone secretion; actin cytoskeleton reorganization; regulation of potassium ion transport; response to starvation; cellular response to hormone stimulus; response to lipopolysaccharide; feeding behavior; response to radiation; response to heat; insulin secretion; pancreatic juice secretion; forebrain development; pancreas development; organ regeneration; response to steroid hormone stimulus; response to glucocorticoid stimulus; positive regulation of calcium ion transport via voltage-gated calcium channel activity; positive regulation of somatostatin secretion; digestion; response to nutrient; axonogenesis; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; reduction of food intake in response to dietary excess; neuron migration; gastric acid secretion; temperature homeostasis
CCKBRpositive regulation of somatostatin secretion; sensory perception; histamine secretion; positive regulation of cell proliferation; behavioral defense response; apoptotic process; cell surface receptor signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; elevation of cytosolic calcium ion concentration; digestion; feeding behavior; positive regulation of synaptic transmission, GABAergic; response to insulin stimulus; regulation of sensory perception of pain; positive regulation of synaptic transmission, glutamatergic; estrous cycle phase; ERK1 and ERK2 cascade; cell proliferation
CCL17chemotaxis; inflammatory response; immune response; G-protein coupled receptor signaling pathway; cell-cell signaling; multicellular organismal development
CCL23cell-cell signaling; monocyte chemotaxis; cellular calcium ion homeostasis; chemotaxis; inflammatory response; immune response; signal transduction; G-protein coupled receptor signaling pathway; negative regulation of C-C chemokine binding; negative regulation of cell proliferation
CCL24positive regulation of Rac GTPase activity; positive regulation of inflammatory response; eosinophil chemotaxis; positive regulation of angiogenesis; positive regulation of actin filament polymerization; positive regulation of cell migration; regulation of cell shape; cell-cell signaling; signal transduction; cytoskeleton organization; immune response; inflammatory response; chemotaxis; positive regulation of endothelial cell proliferation
CCM2vasculogenesis; integrin-mediated signaling pathway; endothelial tube morphogenesis; stress-activated MAPK cascade; multicellular organismal development
CCM2L-
CCNA1regulation of transcription involved in G1/S phase of mitotic cell cycle; male meiosis I; spermatogenesis; regulation of cyclin-dependent protein kinase activity; G2/M transition of mitotic cell cycle; mitotic cell cycle; mitosis; G1/S transition of mitotic cell cycle; cell division
CCNB1IP1organ growth; spermatid development; meiotic metaphase I; chiasma assembly; blastocyst formation; apoptotic process
CCNB2mitosis; growth; T cell homeostasis; thymus development; cell division; regulation of G2/M transition of mitotic cell cycle; in utero embryonic development; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; cell cycle checkpoint
CCNB3cell division; regulation of G2/M transition of mitotic cell cycle; meiosis; cell cycle; regulation of cyclin-dependent protein kinase activity
CCND1response to iron ion; cellular response to organic substance; mitotic cell cycle G1/S transition DNA damage checkpoint; organ regeneration; endoplasmic reticulum unfolded protein response; negative regulation of epithelial cell differentiation; negative regulation of Wnt receptor signaling pathway; response to organic cyclic compound; response to organic nitrogen; response to X-ray; liver development; re-entry into mitotic cell cycle; mitotic cell cycle; S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; G1 phase of mitotic cell cycle; positive regulation of cell proliferation; positive regulation of protein phosphorylation; response to DNA damage stimulus; lactation; response to estrogen stimulus; response to magnesium ion; response to vitamin E; Leydig cell differentiation; positive regulation of mammary gland epithelial cell proliferation; regulation of phosphorylation; response to drug; response to UV-A; fat cell differentiation; response to ethanol; positive regulation of cyclin-depend
CCND2cellular response to insulin stimulus; response to testosterone stimulus; response to peptide hormone stimulus; response to ethanol; regulation of neuron differentiation; positive regulation of cyclin-dependent protein kinase activity; response to cAMP; response to estradiol stimulus; response to organic cyclic compound; spermatogenesis; positive regulation of protein phosphorylation; liver development; ovarian follicle development; positive regulation of epithelial cell proliferation; cell division
CCNE2cell division; mitotic cell cycle; G1/S transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; cell cycle checkpoint
CCNFmitosis; cell division; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; negative regulation of centrosome duplication; cell cycle; placenta development; re-entry into mitotic cell cycle
CCNJ-
CCNL1RNA processing; regulation of cyclin-dependent protein kinase activity; regulation of transcription, DNA-dependent
CCNL2RNA processing; regulation of transcription, DNA-dependent; regulation of cyclin-dependent protein kinase activity
CCNT1regulation of cyclin-dependent protein kinase activity; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; protein phosphorylation; cell cycle; gene expression; viral reproduction; cell division; positive regulation of viral transcription; interspecies interaction between organisms
CCNT2interspecies interaction between organisms; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of cyclin-dependent protein kinase activity; transcription elongation from RNA polymerase II promoter; cell cycle; cell division; gene expression; viral reproduction
CCP110G2/M transition of mitotic cell cycle; mitotic cell cycle; centriole replication; regulation of cytokinesis; centrosome duplication
CCPG1cell cycle
CCR2T-helper 17 cell chemotaxis; cytokine-mediated signaling pathway; cellular homeostasis; positive regulation of cell migration; positive regulation of interferon-gamma production; positive regulation of interleukin-2 production; JAK-STAT cascade; monocyte extravasation; positive regulation of immune complex clearance by monocytes and macrophages; positive regulation of T cell activation; positive regulation of T cell extravasation; positive regulation of monocyte chemotaxis; chemokine-mediated signaling pathway; positive regulation of tumor necrosis factor biosynthetic process; negative regulation of eosinophil degranulation; astrocyte cell migration; interspecies interaction between organisms; innate immune response; positive regulation of alpha-beta T cell proliferation; positive regulation of inflammatory response; elevation of cytosolic calcium ion concentration; positive regulation of T cell chemotaxis; regulation of vascular endothelial growth factor production; response to wounding; blood vessel remodel
CCR3eosinophil chemotaxis; chemotaxis; mast cell chemotaxis; positive regulation of endothelial cell proliferation; positive regulation of angiogenesis; inflammatory response; interspecies interaction between organisms; elevation of cytosolic calcium ion concentration; G-protein signaling, coupled to cAMP nucleotide second messenger; cellular defense response; ERK1 and ERK2 cascade; cell adhesion
CCR4elevation of cytosolic calcium ion concentration; immune response; inflammatory response; chemotaxis; tolerance induction; neuron migration
CCR5cellular defense response; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; cell surface receptor signaling pathway; immune response; inflammatory response; chemotaxis; calcium ion transport; dendritic cell chemotaxis; MAPK cascade; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; viral reproduction; initiation of viral infection; calcium-mediated signaling; signaling; entry into host cell; interspecies interaction between organisms; response to cholesterol; cellular response to lipopolysaccharide; cell-cell signaling
CCR6chemotaxis; cellular defense response; humoral immune response; immune response; cellular component movement; dendritic cell chemotaxis; signal transduction; innate immune response; elevation of cytosolic calcium ion concentration
CCR7positive regulation of dendritic cell antigen processing and presentation; activation of Rho GTPase activity; positive regulation of interleukin-12 production; regulation of interferon-gamma production; response to lipopolysaccharide; ruffle organization; T cell costimulation; positive regulation of pseudopodium assembly; dendritic cell chemotaxis; myeloid dendritic cell chemotaxis; positive regulation of glycoprotein biosynthetic process; positive regulation of humoral immune response; chemotaxis; inflammatory response; immune response; positive regulation of actin filament polymerization; positive regulation of hypersensitivity; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; release of sequestered calcium ion into cytosol; positive regulation of cell motility; negative regulation of leukocyte apoptosis; lymphocyte migration into lymph node; positive regulation of neutrophil chemotaxis; interleukin-12 secretion; response to nitric oxide; positive regulation of
CCR9chemotaxis; immune response; cellular defense response; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway
CCRL2-
CCSsuperoxide metabolic process; intracellular copper ion transport; oxidation-reduction process; copper ion transmembrane transport; metal ion transport; removal of superoxide radicals
CCSER2-
CCT2protein folding; chaperone-mediated protein complex assembly; cellular protein metabolic process; 'de novo' posttranslational protein folding
CCT3'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding
CCT4protein folding; cellular protein metabolic process; 'de novo' posttranslational protein folding
CCT5'de novo' posttranslational protein folding; cellular protein metabolic process; response to virus; protein folding
CCT6Bspermatogenesis; protein transport; chaperone-mediated protein complex assembly; protein folding
CCT8'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding
CD101cell surface receptor signaling pathway
CD109-
CD14cell surface receptor signaling pathway; inflammatory response; Toll signaling pathway; response to heat; positive regulation of tumor necrosis factor production; innate immune response; positive regulation of cytokine secretion; cellular response to lipopolysaccharide; cellular response to lipoteichoic acid; apoptotic process; phagocytosis
CD151cell junction assembly; cell adhesion; hemidesmosome assembly
CD163acute-phase response; inflammatory response
CD163L1-
CD164heterophilic cell-cell adhesion; signal transduction; hemopoiesis; negative regulation of cell proliferation; muscle organ development; immune response; cell adhesion; multicellular organismal development; negative regulation of cell adhesion
CD164L2-
CD180inflammatory response; innate immune response
CD1Aantigen processing and presentation; immune response
CD1Bantigen processing and presentation; immune response
CD1Cimmune response; T cell activation involved in immune response; antigen processing and presentation
CD1Dantigen processing and presentation, endogenous lipid antigen via MHC class Ib; positive regulation of innate immune response; T cell selection; positive regulation of T cell proliferation; heterotypic cell-cell adhesion; antigen processing and presentation; detection of bacterium; interspecies interaction between organisms
CD1Eantigen processing and presentation; immune response
CD200R1interspecies interaction between organisms; regulation of immune response
CD22cell adhesion
CD226positive regulation of mast cell activation; signal transduction; cell adhesion; positive regulation of immunoglobulin mediated immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; cytokine production; cell recognition; positive regulation of Fc receptor mediated stimulatory signaling pathway; regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity
CD244signal transduction; blood coagulation; leukocyte migration
CD247regulation of defense response to virus by virus; regulation of immune response; T cell costimulation; viral reproduction; cell surface receptor signaling pathway; T cell receptor signaling pathway; interspecies interaction between organisms
CD248-
CD28T cell activation; positive regulation of viral genome replication; negative thymic T cell selection; regulation of defense response to virus by virus; positive regulation of isotype switching to IgG isotypes; positive regulation of alpha-beta T cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of mitosis; positive regulation of anti-apoptosis; positive regulation of translation; positive regulation of interleukin-2 biosynthetic process; positive regulation of T cell proliferation; cytokine biosynthetic process; T cell costimulation; viral reproduction; induction of apoptosis by extracellular signals; cell surface receptor signaling pathway; humoral immune response; immune response; positive regulation of inflammatory response to antigenic stimulus; regulatory T cell differentiation
CD2APsignal transduction; mitosis; cell cycle; cell division; substrate-dependent cell migration, cell extension; protein complex assembly
CD2BP2nuclear mRNA splicing, via spliceosome; assembly of spliceosomal tri-snRNP; negative regulation of phosphatase activity; gene expression; RNA splicing
CD300Ccellular defense response
CD300LG-
CD36positive regulation of cell-matrix adhesion; pattern recognition receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of reactive oxygen species metabolic process; positive regulation of blood microparticle formation; negative regulation of gene expression; positive regulation of interleukin-6 production; positive regulation of interleukin-12 production; cholesterol transport; positive regulation of blood coagulation; platelet activation; cGMP-mediated signaling; lipid storage; plasma membrane long-chain fatty acid transport; positive regulation of cholesterol storage; positive regulation of macrophage derived foam cell differentiation; cellular response to hydroperoxide; blood coagulation; nitric oxide mediated signal transduction; cell surface receptor signaling pathway; cell adhesion; phagocytosis, recognition; transport; lipid metabolic process; platelet degranulation; antigen processing and presentation of exogenous peptide antigen via MHC
CD3Enegative regulation of smoothened signaling pathway; positive regulation of alpha-beta T cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; regulation of immune response; positive regulation of calcium-mediated signaling; T cell receptor signaling pathway; positive regulation of interleukin-2 biosynthetic process; negative thymic T cell selection; regulation of apoptotic process; T cell activation; positive regulation of T cell proliferation; positive regulation of interleukin-4 production; positive regulation of interferon-gamma production; T cell costimulation; induction of apoptosis by extracellular signals; response to nutrient; G-protein coupled receptor signaling pathway; positive regulation of T cell anergy; protein complex assembly; cell surface receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; T cell differentiation in thymus; signal complex assembly
CD3EAPrRNA transcription; transmembrane receptor protein tyrosine kinase signaling pathway
CD40positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein phosphorylation; positive regulation of endothelial cell apoptosis; positive regulation of protein kinase C signaling cascade; cellular response to mechanical stimulus; defense response to virus; positive regulation of NF-kappaB transcription factor activity; regulation of immunoglobulin secretion; regulation of immune response; positive regulation of isotype switching to IgG isotypes; positive regulation of MAP kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of Cdc42 GTPase activity; B cell proliferation; immune response-regulating cell surface receptor signaling pathway; protein complex assembly; cellular calcium ion homeostasis; inflammatory response; signal transduction; platelet activation; positive regulation of B cell proliferation; positive regulation of interleukin-12 production; positive regulation of Rac GTPase activity; positive regulation of tyrosine
CD40LGimmune response; positive regulation of endothelial cell apoptosis; regulation of immunoglobulin secretion; regulation of immune response; positive regulation of MHC class II biosynthetic process; isotype switching; B cell proliferation; positive regulation of interleukin-12 production; positive regulation of interleukin-10 production; positive regulation of B cell proliferation; B cell differentiation; platelet activation; leukocyte cell-cell adhesion; positive regulation of interferon-gamma production; inflammatory response; anti-apoptosis; positive regulation of immune response to tumor cell
CD47cell adhesion; integrin-mediated signaling pathway; blood coagulation; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; positive regulation of T cell activation; leukocyte migration
CD48leukocyte migration; mast cell activation; T cell activation; blood coagulation; defense response; signal transduction
CD5T cell costimulation; induction of apoptosis by extracellular signals; cell proliferation; cell recognition
CD55complement activation, classical pathway; elevation of cytosolic calcium ion concentration; innate immune response; respiratory burst
CD58cell adhesion; blood coagulation; cell-cell adhesion; leukocyte migration
CD5Lcellular defense response; apoptotic process
CD6cell adhesion
CD68-
CD7T cell activation; homeostasis of number of cells within a tissue; transmembrane receptor protein tyrosine kinase signaling pathway; immune response
CD79AB cell receptor signaling pathway; B cell activation; B cell proliferation; B cell differentiation; cell surface receptor signaling pathway
CD83positive regulation of CD4-positive, alpha-beta T cell differentiation; defense response; humoral immune response; signal transduction; response to organic cyclic compound; negative regulation of interleukin-4 production; positive regulation of interleukin-10 production; positive regulation of interleukin-2 production
CD9oligodendrocyte development; platelet degranulation; cellular component movement; cell adhesion; fusion of sperm to egg plasma membrane; brain development; blood coagulation; negative regulation of cell proliferation; paranodal junction assembly; platelet activation; response to water deprivation
CD96regulation of immune response; cell adhesion; immune response
CD99L2cell adhesion
CDAN1-
CDC14Acell proliferation; cell cycle; cell division
CDC16anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; mitosis; regulation of mitosis; mitotic cell cycle spindle assembly checkpoint; cell proliferation; mitotic cell cycle; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell cycle checkpoint; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination
CDC20B-
CDC23G1 phase of mitotic cell cycle; mitotic cell cycle spindle assembly checkpoint; regulation of exit from mitosis; protein ubiquitination; regulation of mitotic metaphase/anaphase transition; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell cycle checkpoint; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; protein K11-linked ubiquitination; mitotic metaphase/anaphase transition; mitotic metaphase plate congression; mitosis; cell cycle; ubiquitin-dependent protein catabolic process; mitotic cell cycle
CDC25ADNA replication; mitotic cell cycle; cell cycle checkpoint; regulation of cyclin-dependent protein kinase activity; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; cell division; cellular response to UV; response to radiation; cell proliferation; mitosis
CDC25Bpositive regulation of protein kinase activity; positive regulation of cell cycle cytokinesis; cell division; positive regulation of mitotic cell cycle; peptidyl-tyrosine dephosphorylation; positive regulation of cell proliferation; female meiosis I; mitosis; protein phosphorylation; oocyte maturation; mitotic cell cycle; G2/M transition of mitotic cell cycle
CDC25Cregulation of cyclin-dependent protein kinase activity; regulation of cell cycle; cell division; interspecies interaction between organisms; peptidyl-tyrosine dephosphorylation; cell proliferation; traversing start control point of mitotic cell cycle; regulation of mitosis; DNA replication; mitotic cell cycle; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; cell cycle checkpoint
CDC26mitosis; protein K11-linked ubiquitination; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell cycle checkpoint; cell division; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of mitotic metaphase/anaphase transition; mitotic cell cycle spindle assembly checkpoint; mitotic cell cycle
CDC37regulation of cyclin-dependent protein kinase activity; protein targeting; regulation of interferon-gamma-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway
CDC42BPAintracellular signal transduction; protein phosphorylation; cell migration; actin cytoskeleton reorganization; actomyosin structure organization
CDC42BPBintracellular signal transduction; actomyosin structure organization; cell migration; signal transduction; establishment or maintenance of cell polarity; cytoskeleton organization; protein phosphorylation; actin cytoskeleton reorganization
CDC42BPGintracellular signal transduction; protein phosphorylation; actin cytoskeleton reorganization
CDC42EP1positive regulation of pseudopodium assembly; regulation of cell shape
CDC42EP2actin cytoskeleton organization; positive regulation of actin filament polymerization; positive regulation of pseudopodium assembly; positive regulation of protein complex assembly; positive regulation of Rho GTPase activity; regulation of cell shape; actin filament organization
CDC45DNA replication checkpoint; cell cycle checkpoint; G1/S transition of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; S phase of mitotic cell cycle; M/G1 transition of mitotic cell cycle; DNA replication; DNA-dependent DNA replication initiation; DNA strand elongation involved in DNA replication; mitotic cell cycle
CDC6regulation of mitotic anaphase; positive regulation of cell cycle cytokinesis; positive regulation of chromosome segregation; cell division; negative regulation of cell proliferation; negative regulation of DNA replication; traversing start control point of mitotic cell cycle; mitosis; DNA replication; mitotic cell cycle; M/G1 transition of mitotic cell cycle; S phase of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity; DNA replication checkpoint; cell cycle checkpoint
CDC7phosphorylation; cell cycle checkpoint; G1/S transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; positive regulation of cell proliferation; regulation of S phase; cell division
CDC73transcription, DNA-dependent; negative regulation of epithelial cell proliferation; negative regulation of fibroblast proliferation; histone H2B ubiquitination; protein destabilization; histone monoubiquitination; cell cycle; negative regulation of transcription from RNA polymerase II promoter
CDCA2mitosis; cell cycle; cell division
CDCA3cell division; mitosis; cell cycle
CDCA5double-strand break repair; cell cycle; regulation of cohesin localization to chromatin; G1/S transition of mitotic cell cycle; mitotic sister chromatid cohesion; mitosis; mitotic chromosome condensation; mitotic metaphase plate congression; cell division; interphase of mitotic cell cycle
CDCA7Lpositive regulation of cell proliferation; regulation of transcription, DNA-dependent
CDCP2-
CDH1apoptotic process; cellular response to lithium ion; cellular response to indole-3-methanol; cellular component disassembly involved in apoptosis; cell adhesion; homophilic cell adhesion; synapse assembly; response to toxin; response to organic substance; cell-cell adhesion; pituitary gland development; neuron projection development; cell junction assembly; adherens junction organization; response to drug; positive regulation of transcription factor import into nucleus; cell-cell junction organization; positive regulation of transcription, DNA-dependent; regulation of immune response; negative regulation of cell-cell adhesion
CDH10cell-cell junction organization; homophilic cell adhesion; cell-cell adhesion; cell junction assembly; adherens junction organization
CDH11cell-cell junction organization; adherens junction organization; cell junction assembly; cell-cell adhesion; homophilic cell adhesion; cell adhesion; ossification; skeletal system development
CDH12cell-cell junction organization; adherens junction organization; cell junction assembly; cell-cell adhesion; homophilic cell adhesion
CDH15muscle cell differentiation; positive regulation of muscle cell differentiation; cell-cell junction organization; cell junction assembly; homophilic cell adhesion; cell adhesion; adherens junction organization
CDH16cell adhesion; homophilic cell adhesion
CDH18cell adhesion; homophilic cell adhesion; cell junction assembly; adherens junction organization; cell-cell junction organization
CDH19cell-cell adhesion; homophilic cell adhesion; cell adhesion
CDH2regulation of axonogenesis; adherens junction organization; cell junction assembly; regulation of protein localization; regulation of myelination; cell migration; calcium-dependent cell-cell adhesion; synapse assembly; heterophilic cell-cell adhesion; homophilic cell adhesion; cell adhesion; regulation of Rho protein signal transduction; muscle cell differentiation; positive regulation of MAPK cascade; cell-cell junction organization; blood vessel morphogenesis; striated muscle cell differentiation; positive regulation of muscle cell differentiation; negative regulation of canonical Wnt receptor signaling pathway
CDH20homophilic cell adhesion; cell-cell adhesion
CDH22homophilic cell adhesion; cell adhesion
CDH24cell junction assembly; cell-cell adhesion; homophilic cell adhesion; adherens junction organization; cell-cell junction organization
CDH26cell adhesion; homophilic cell adhesion
CDH3adherens junction organization; cell adhesion; cell-cell junction organization; response to stimulus; homophilic cell adhesion; visual perception; cell junction assembly
CDH4cell adhesion; homophilic cell adhesion; heterophilic cell-cell adhesion; axon guidance; cell-cell junction organization; cell junction assembly; adherens junction organization; positive regulation of axon extension
CDH5blood vessel maturation; cell adhesion; homophilic cell adhesion; negative regulation of cell proliferation; cell junction assembly; adherens junction organization; cell-cell junction organization; regulation of establishment of cell polarity
CDH6cell junction assembly; cell-cell junction organization; adherens junction organization; homophilic cell adhesion; cell adhesion
CDH7homophilic cell adhesion; cell-cell adhesion; cell junction assembly; adherens junction organization; cell-cell junction organization
CDH8cell adhesion; homophilic cell adhesion; cell junction assembly; adherens junction organization; cell-cell junction organization
CDH9cell-cell junction organization; adherens junction organization; cell junction assembly; cell-cell adhesion; homophilic cell adhesion
CDHR1photoreceptor cell maintenance; homophilic cell adhesion; cell adhesion
CDHR2cell adhesion; homophilic cell adhesion; negative regulation of cell growth
CDHR5calcium-dependent cell-cell adhesion; cell adhesion; homophilic cell adhesion
CDK1response to drug; positive regulation of gene expression; protein localization to kinetochore; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; positive regulation of protein import into nucleus, translocation; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; organ regeneration; chromosome condensation; cell migration; response to activity; response to amine stimulus; response to organic cyclic compound; regulation of Schwann cell differentiation; TRIF-dependent toll-like receptor signaling pathway; innate immune response; response to ethanol; positive regulation of DNA replication; positive regulation of mitotic cell cycle; regulation of embryonic development; response to cadmium ion; response to copper ion; nerve growth factor receptor signaling pathway; response to axon injury; cell division; stress-activated MAPK cascade; positive regulation of ubiqu
CDK12mRNA processing; regulation of MAP kinase activity; phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; RNA splicing
CDK13phosphorylation of RNA polymerase II C-terminal domain; hemopoiesis; interspecies interaction between organisms; positive regulation of cell proliferation; multicellular organismal development; regulation of mitosis; protein phosphorylation; mRNA processing; alternative nuclear mRNA splicing, via spliceosome; RNA splicing
CDK14regulation of canonical Wnt receptor signaling pathway; cell division; Wnt receptor signaling pathway; G2/M transition of mitotic cell cycle; cell cycle
CDK2potassium ion transport; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; histone phosphorylation; phosphorylation; cell cycle checkpoint; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2 phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; M/G1 transition of mitotic cell cycle; mitotic cell cycle; DNA replication; regulation of DNA replication; DNA repair; protein phosphorylation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cell cycle; mitosis; traversing start control point of mitotic cell cycle; meiosis; Ras protein signal transduction; cell division; blood coagulation; positive regulation of cell proliferation; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; centrosome duplication; positive regulation of transcription, DNA-dependent; mitotic cell cycle G1/S transition DNA damage checkpoint; regulation of gene silencing; cellular response t
CDK20cell division; multicellular organismal development
CDK3G1/S transition of mitotic cell cycle; mitosis; cell proliferation; G0 to G1 transition; cell division
CDK4positive regulation of fibroblast proliferation; regulation of cell cycle; cell division; response to drug; regulation of gene expression; positive regulation of cell proliferation; signal transduction; protein phosphorylation; mitotic cell cycle; S phase of mitotic cell cycle; cell cycle; G1/S transition of mitotic cell cycle; G1 phase of mitotic cell cycle
CDK5R1negative regulation of transcription, DNA-dependent; regulation of neuron differentiation; positive regulation of neuron apoptosis; ionotropic glutamate receptor signaling pathway; regulation of actin cytoskeleton organization; ephrin receptor signaling pathway; regulation of dendritic spine morphogenesis; neuron migration; regulation of microtubule cytoskeleton organization; neuron projection development; neuron differentiation; cerebral cortex radially oriented cell migration; peptidyl-threonine phosphorylation; peptidyl-serine phosphorylation; phosphorylation; embryo development; cell proliferation; brain development; axonal fasciculation; axon guidance; G-protein coupled acetylcholine receptor signaling pathway; protein phosphorylation; regulation of cyclin-dependent protein kinase activity; neuron cell-cell adhesion; positive regulation of protein serine/threonine kinase activity
CDK5R2regulation of cyclin-dependent protein kinase activity
CDK5RAP2microtubule bundle formation; regulation of spindle checkpoint; centrosome organization; chromosome segregation; negative regulation of centriole replication; positive regulation of transcription, DNA-dependent; negative regulation of neuron differentiation; G2/M transition of mitotic cell cycle; regulation of neuron differentiation; establishment of mitotic spindle orientation; neurogenesis; brain development; microtubule cytoskeleton organization; mitotic cell cycle
CDK5RAP3regulation of neuron differentiation; brain development; regulation of cyclin-dependent protein kinase activity
CDK7transcription from RNA polymerase II promoter; mRNA capping; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; protein phosphorylation; cell cycle arrest; cell proliferation; gene expression; viral reproduction; androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; cell division; transcription elongation from RNA polymerase I promoter; regulation of cyclin-dependent protein kinase activity; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; mitotic cell cycle; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; nucleotide-ex
CDK8gene expression; protein phosphorylation; regulation of transcription, DNA-dependent
CDK9regulation of DNA repair; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; protein phosphorylation; cell cycle; gene expression; viral reproduction; regulation of histone modification; replication fork arrest; positive regulation of viral transcription; negative regulation of cell cycle arrest; cellular response to cytokine stimulus; cell proliferation
CDKAL1RNA modification
CDKL2protein phosphorylation; signal transduction; sex differentiation
CDKL4-
CDKL5neuron migration; protein phosphorylation; positive regulation of Rac GTPase activity; positive regulation of axon extension; positive regulation of dendrite morphogenesis; regulation of dendrite development; protein autophosphorylation
CDKN1Apositive regulation of programmed cell death; negative regulation of cell growth; negative regulation of apoptotic process; response to drug; negative regulation of phosphorylation; regulation of protein import into nucleus, translocation; cellular response to extracellular stimulus; organ regeneration; positive regulation of B cell proliferation; response to organic nitrogen; negative regulation of cyclin-dependent protein kinase activity; positive regulation of anti-apoptosis; response to arsenic-containing substance; positive regulation of fibroblast proliferation; response to corticosterone stimulus; response to hyperoxia; cellular response to ionizing radiation; cellular senescence; stress-induced premature senescence; regulation of DNA biosynthetic process; positive regulation of reactive oxygen species metabolic process; response to organic cyclic compound; cell cycle checkpoint; regulation of cyclin-dependent protein kinase activity; G1 phase of mitotic cell cycle; G1/S transition of mitotic cell cycl
CDKN2Anegative regulation of B cell proliferation; protein destabilization; negative regulation of cell growth; regulation of G2/M transition of mitotic cell cycle; apoptotic mitochondrial changes; negative regulation of cell proliferation; Ras protein signal transduction; cell cycle arrest; cell cycle; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; negative regulation of protein kinase activity; rRNA processing; DNA fragmentation involved in apoptotic nuclear change; negative regulation of cell-matrix adhesion; mitotic cell cycle; protein polyubiquitination; G1/S transition of mitotic cell cycle; G1 phase of mitotic cell cycle; cell cycle checkpoint; negative regulation of NF-kappaB transcription factor activity; positive regulation of cellular senescence; positive regulation of macrophage apoptosis; replicative senescence; cellular senescence; positive regulation of cell cycle arrest; protein K63-linked ubiquitination; negative regulation of ubiquitin-pro
CDO1response to amino acid stimulus; oxidation-reduction process; inflammatory response; cysteine metabolic process; sulfur amino acid catabolic process; sulfur amino acid biosynthetic process; sulfur amino acid metabolic process; response to cAMP; response to glucocorticoid stimulus; response to ethanol; small molecule metabolic process; taurine biosynthetic process; cellular nitrogen compound metabolic process; response to glucagon stimulus; L-cysteine catabolic process; response to organic nitrogen; lactation
CDONpositive regulation of muscle cell differentiation; muscle cell differentiation; cell adhesion
CDRT4-
CDS1CDP-choline pathway; phosphatidylinositol biosynthetic process; signal transduction; phototransduction; phospholipid biosynthetic process; CDP-diacylglycerol biosynthetic process
CDT1DNA replication checkpoint; M/G1 transition of mitotic cell cycle; G1/S transition of mitotic cell cycle; regulation of DNA-dependent DNA replication initiation; regulation of S phase of mitotic cell cycle; DNA replication; mitotic cell cycle; S phase of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle
CDX2organ morphogenesis; pattern specification process; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; placenta development; trophectodermal cell differentiation; blastocyst development; blood vessel development; negative regulation of transcription from RNA polymerase II promoter; somatic stem cell maintenance; positive regulation of cell differentiation; anterior/posterior pattern specification; labyrinthine layer development
CEACAM1cell migration; integrin-mediated signaling pathway; homophilic cell adhesion; angiogenesis
CEACAM7-
CEACAM8immune response
CEBPZregulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter
CECR1hypoxanthine salvage; inosine biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; multicellular organismal development; adenosine catabolic process
CECR5metabolic process
CECR6-
CELA1post-embryonic development; exocrine pancreas development; multicellular organism growth; negative regulation of transcription from RNA polymerase II promoter; proteolysis; regulation of cell proliferation; regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; pancreas morphogenesis; inflammatory response; Wnt receptor signaling pathway
CELF1mRNA processing; mRNA splice site selection; germ cell development; embryo development; RNA interference; regulation of RNA splicing
CELF2regulation of heart contraction; mRNA processing; RNA processing
CELF3nuclear mRNA splicing, via spliceosome; spermatogenesis; RNA splicing; sperm motility; positive regulation of nuclear mRNA splicing, via spliceosome; regulation of alternative nuclear mRNA splicing, via spliceosome
CELF6mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome
CELSR1anterior/posterior pattern specification; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; establishment of body hair planar orientation; apical protein localization; inner ear morphogenesis; establishment of planar polarity of embryonic epithelium; wound healing; regulation of actin cytoskeleton organization; establishment of planar polarity; locomotory behavior; central nervous system development; multicellular organismal development; Rho protein signal transduction; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; homophilic cell adhesion; cell adhesion; hair follicle development; neural tube closure; neuron migration; lateral sprouting involved in lung morphogenesis; planar cell polarity pathway involved in neural tube closure; protein localization involved in establishment of planar polarity; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
CELSR2neuron migration; regulation of transcription, DNA-dependent; cell adhesion; homophilic cell adhesion; G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; spermatogenesis; Wnt receptor signaling pathway; neural plate anterior/posterior regionalization; multicellular organismal development; regulation of cell-cell adhesion; dendrite morphogenesis
CELSR3axonal fasciculation; multicellular organismal development; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; homophilic cell adhesion; cell adhesion; neuron migration
CEMIP-
CENPBregulation of transcription, DNA-dependent
CENPEmitotic cell cycle spindle assembly checkpoint; positive regulation of attachment of spindle microtubules to kinetochore; multicellular organismal development; kinetochore assembly; cell division; regulation of developmental process; positive regulation of protein kinase activity; positive regulation of mitotic metaphase/anaphase transition; establishment of protein localization; blood coagulation; mitotic metaphase plate congression; regulation of mitosis; microtubule-based movement; mitotic cell cycle; mitotic prometaphase; mitotic metaphase; M phase of mitotic cell cycle; mitotic chromosome movement towards spindle pole
CENPFG2 phase of mitotic cell cycle; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; DNA replication; chromosome segregation; mitotic cell cycle spindle assembly checkpoint; multicellular organismal development; muscle organ development; cell proliferation; regulation of G2/M transition of mitotic cell cycle; protein transport; regulation of striated muscle tissue development; response to drug; negative regulation of transcription, DNA-dependent; cell division; metaphase plate congression; kinetochore assembly; cell differentiation
CENPJmicrotubule polymerization; G2/M transition of mitotic cell cycle; mitotic cell cycle; microtubule nucleation; centriole replication; regulation of centriole replication; cell division
CENPLM phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle
CENPNM phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; nucleosome assembly; CenH3-containing nucleosome assembly at centromere
CENPOCenH3-containing nucleosome assembly at centromere; M phase of mitotic cell cycle; mitotic prometaphase; mitotic cell cycle; nucleosome assembly; chromosome segregation; cell division
CENPQnucleosome assembly; CenH3-containing nucleosome assembly at centromere; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle
CENPTmitotic prometaphase; M phase of mitotic cell cycle; mitotic cell cycle
CEP104-
CEP112-
CEP126-
CEP128-
CEP131spermatogenesis; multicellular organismal development; cell differentiation; mitotic cell cycle; G2/M transition of mitotic cell cycle
CEP135G2/M transition of mitotic cell cycle; mitotic cell cycle; centriole replication; centriole-centriole cohesion
CEP152G2/M transition of mitotic cell cycle; mitotic cell cycle; centrosome duplication
CEP164DNA repair; G2/M transition of mitotic cell cycle; mitotic cell cycle; mitosis; cell division
CEP250G2/M transition of mitotic cell cycle; mitotic cell cycle; protein localization; centriole-centriole cohesion; regulation of centriole-centriole cohesion
CEP41G2/M transition of mitotic cell cycle; protein polyglutamylation; mitotic cell cycle; cilium assembly
CEP70mitotic cell cycle; G2/M transition of mitotic cell cycle
CEP72mitotic cell cycle; G2/M transition of mitotic cell cycle; spindle organization; gamma-tubulin complex localization
CEP83-
CEP85-
CEP85L-
CEP89-
CEP97-
CEPT1phospholipid biosynthetic process; lipid metabolic process
CER1negative regulation of BMP signaling pathway by extracellular sequestering of BMP; negative regulation of mesoderm development; cellular response to BMP stimulus; negative regulation of activin receptor signaling pathway; BMP signaling pathway; ureteric bud development; growth plate cartilage chondrocyte proliferation; negative regulation of Wnt receptor signaling pathway; bone mineralization
CERCAMlipopolysaccharide biosynthetic process; leukocyte cell-cell adhesion; cell adhesion; cellular component movement
CERKLactivation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; anti-apoptosis
CERS4ceramide biosynthetic process; sphingolipid metabolic process; lipid biosynthetic process; sphingolipid biosynthetic process; small molecule metabolic process
CERS5sphingolipid metabolic process; lipid biosynthetic process; sphingolipid biosynthetic process; small molecule metabolic process; ceramide biosynthetic process
CERS6sphingolipid metabolic process; ceramide biosynthetic process; small molecule metabolic process; sphingolipid biosynthetic process; lipid biosynthetic process
CES2catabolic process
CES3-
CES4A-
CES5A-
CETN2G2/M transition of mitotic cell cycle; mitotic cell cycle; nucleotide-excision repair; mitosis; centriole replication; spermatogenesis; regulation of cytokinesis; cell division
CFAP100-
CFAP126-
CFAP157-
CFAP206-
CFAP221-
CFAP43-
CFAP44-
CFAP45-
CFAP46-
CFAP52-
CFAP53-
CFAP58-
CFAP61-
CFAP69-
CFAP70-
CFAP77-
CFHcomplement activation, alternative pathway; complement activation
CFHR5complement activation, alternative pathway
CFIinnate immune response; complement activation, classical pathway; proteolysis
CFPimmune response; complement activation; complement activation, alternative pathway; defense response to bacterium; innate immune response
CFTRpositive regulation of vasodilation; transport; transmembrane transport; response to estrogen stimulus; response to peptide hormone stimulus; response to drug; response to cytokine stimulus; cellular response to hormone stimulus; lung development; transepithelial chloride transport; cholesterol transport; iodide transport; bicarbonate transport; respiratory gaseous exchange; water transport; chloride transport; ion transport; cholesterol biosynthetic process
CGAthyroid gland development; thyroid hormone generation; signal transduction; cell-cell signaling; gonad development; peptide hormone processing; luteinizing hormone secretion; cellular response to hormone stimulus; cellular nitrogen compound metabolic process; small molecule metabolic process; negative regulation of organ growth; follicle-stimulating hormone secretion; developmental growth
CGN-
CGNL1-
CGREF1negative regulation of cell proliferation; cell adhesion; cell cycle arrest; cell cycle; response to stress
CH25Hfatty acid biosynthetic process; bile acid biosynthetic process; cholesterol metabolic process; bile acid metabolic process; sterol biosynthetic process; small molecule metabolic process; lipid metabolic process
CHADregulation of cell growth
CHAF1Acell cycle; protein complex assembly; regulation of transcription, DNA-dependent; DNA replication-dependent nucleosome assembly; chromatin assembly; DNA repair; DNA replication
CHAF1BDNA replication-dependent nucleosome assembly; DNA repair; DNA replication; regulation of transcription, DNA-dependent; protein complex assembly; cell cycle; chromatin assembly
CHAMP1sister chromatid biorientation; attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; protein localization to microtubule; protein localization to kinetochore
CHCHD6-
CHCHD7-
CHD1chromatin remodeling; regulation of transcription from RNA polymerase II promoter
CHD1Lchromatin remodeling; response to DNA damage stimulus; ATP catabolic process; DNA repair
CHD2regulation of transcription from RNA polymerase II promoter
CHD3regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; spindle organization; chromatin modification; centrosome organization
CHD4regulation of transcription from RNA polymerase II promoter; chromatin modification
CHD5chromatin modification; regulation of transcription, DNA-dependent
CHD6regulation of transcription, DNA-dependent; chromatin remodeling; nervous system development
CHDHalcohol metabolic process
CHEK2response to gamma radiation; DNA damage response, signal transduction resulting in induction of apoptosis; double-strand break repair; regulation of protein catabolic process; signal transduction in response to DNA damage; cellular protein catabolic process; positive regulation of transcription, DNA-dependent; protein autophosphorylation; cell division; signal transduction involved in intra-S DNA damage checkpoint; spindle assembly involved in mitosis; replicative senescence; DNA damage induced protein phosphorylation; cell cycle checkpoint; DNA damage checkpoint; G2/M transition of mitotic cell cycle; regulation of transcription, DNA-dependent; apoptotic process; response to DNA damage stimulus; cell cycle
CHERPpositive regulation of NFAT protein import into nucleus; release of sequestered calcium ion into cytosol; negative regulation of cell proliferation; nervous system development; cellular calcium ion homeostasis; RNA processing
CHGAregulation of blood pressure
CHI3L1positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein kinase B signaling cascade; interleukin-8 secretion; cellular response to tumor necrosis factor; cartilage development; positive regulation of angiogenesis; response to tumor necrosis factor; lung development; response to mechanical stimulus; activation of NF-kappaB-inducing kinase activity; inflammatory response; carbohydrate metabolic process; cellular response to interleukin-1; response to interleukin-6; response to interleukin-1; positive regulation of ERK1 and ERK2 cascade; chitin catabolic process
CHI3L2carbohydrate metabolic process; chitin catabolic process
CHIAdigestion; production of molecular mediator involved in inflammatory response; response to fungus; positive regulation of chemokine secretion; chitin metabolic process; carbohydrate metabolic process; chitin catabolic process; cell wall chitin metabolic process; apoptotic process; response to acid; polysaccharide catabolic process; immune response
CHID1carbohydrate metabolic process; chitin catabolic process; innate immune response
CHIT1chitin catabolic process; response to bacterium; immune response; carbohydrate metabolic process; polysaccharide catabolic process
CHKAlipid metabolic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; CDP-choline pathway; lipid transport; signal transduction; phospholipid biosynthetic process; choline metabolic process
CHKBphospholipid biosynthetic process; muscle organ development; phosphatidylethanolamine biosynthetic process; CDP-choline pathway
CHL1multicellular organismal development; signal transduction; nervous system development; axon guidance; cell differentiation; cell adhesion
CHMprotein geranylgeranylation; visual perception; intracellular protein transport; blood vessel development; response to stimulus
CHMP2Aendosome transport; cellular membrane organization; protein transport
CHMP7protein transport; cellular membrane organization; endosome transport; late endosome to vacuole transport
CHN2regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity; small GTPase mediated signal transduction; acrosome assembly
CHODLmuscle organ development
CHORDC1negative regulation of Rho-dependent protein serine/threonine kinase activity; regulation of response to stress; chaperone-mediated protein folding; regulation of centrosome duplication
CHP2-
CHPF-
CHPF2-
CHPT1platelet activating factor biosynthetic process; regulation of cell growth; phospholipid biosynthetic process; CDP-choline pathway; phosphatidylcholine biosynthetic process; lipid metabolic process
CHRDL1ossification; multicellular organismal development; nervous system development; cell differentiation; BMP signaling pathway
CHRDL2multicellular organismal development; cartilage development; cell differentiation; ossification
CHRM2G-protein coupled receptor signaling pathway; regulation of smooth muscle contraction; G-protein signaling, coupled to cAMP nucleotide second messenger; activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway; synaptic transmission; nervous system development; regulation of heart contraction; response to virus; G-protein signaling, coupled to cyclic nucleotide second messenger
CHRM3digestion; regulation of insulin secretion; positive regulation of smooth muscle contraction; small molecule metabolic process; cell proliferation; nervous system development; G-protein coupled acetylcholine receptor signaling pathway; G-protein coupled receptor signaling pathway; signal transduction; protein modification process; energy reserve metabolic process; regulation of vascular smooth muscle contraction
CHRM5cell proliferation; inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway; G-protein coupled acetylcholine receptor signaling pathway; dopamine transport; transmission of nerve impulse; regulation of phosphatidylinositol dephosphorylation
CHRNA1regulation of action potential in neuron; neuron homeostasis; neuromuscular process; musculoskeletal movement; skeletal muscle tissue growth; muscle cell homeostasis; regulation of membrane potential; neuromuscular junction development; neuromuscular synaptic transmission; synaptic transmission; signal transduction; ion transport; transport; skeletal muscle contraction
CHRNA4calcium ion transport; ion transport; DNA repair; response to hypoxia; regulation of action potential; regulation of inhibitory postsynaptic membrane potential; cognition; response to oxidative stress; signal transduction; synaptic transmission; synaptic transmission, cholinergic; locomotory behavior; regulation of dopamine secretion; sensory perception of pain; response to nicotine; behavioral response to nicotine; B cell activation; regulation of membrane potential; neurological system process; membrane depolarization
CHRNA6membrane depolarization; signal transduction; synaptic transmission; regulation of dopamine secretion; ion transmembrane transport; transport; cation transport
CHRNA7memory; cognition; activation of MAPK activity; response to hypoxia; ion transport; calcium ion transport; cellular calcium ion homeostasis; signal transduction; synaptic transmission; positive regulation of angiogenesis; response to chemical stimulus; response to nicotine; negative regulation of tumor necrosis factor production; positive regulation of cell proliferation
CHRNB1regulation of membrane potential; muscle fiber development; behavioral response to nicotine; ion transmembrane transport; neuromuscular synaptic transmission; synaptic transmission, cholinergic; signal transduction; muscle contraction; cation transport; postsynaptic membrane organization; neurological system process
CHRNB2regulation of synapse assembly; vestibulocochlear nerve development; membrane depolarization; cognition; neurological system process; regulation of dendrite morphogenesis; negative regulation of action potential; response to ethanol; regulation of circadian sleep/wake cycle, non-REM sleep; regulation of circadian sleep/wake cycle, REM sleep; response to cocaine; B cell activation; regulation of dopamine metabolic process; social behavior; behavioral response to nicotine; response to nicotine; ion transmembrane transport; positive regulation of dopamine secretion; positive regulation of synaptic transmission, dopaminergic; regulation of synaptic transmission, dopaminergic; positive regulation of B cell proliferation; central nervous system projection neuron axonogenesis; lateral geniculate nucleus development; optic nerve morphogenesis; locomotory behavior; calcium ion transport; smooth muscle contraction; signal transduction; synaptic transmission; synaptic transmission, cholinergic; visual perception; sensor
CHRNB3transport; synaptic transmission, cholinergic; synaptic transmission; signal transduction; ion transport
CHRNB4regulation of neurotransmitter secretion; ion transport; regulation of smooth muscle contraction; signal transduction; synaptic transmission; synaptic transmission, cholinergic; locomotory behavior; behavioral response to nicotine; synaptic transmission involved in micturition; regulation of action potential
CHRNDregulation of membrane potential; transport; cation transport; muscle contraction; signal transduction; synaptic transmission; ion transmembrane transport; skeletal muscle tissue growth; musculoskeletal movement; neuromuscular process
CHRNGregulation of membrane potential; ion transmembrane transport; synaptic transmission; signal transduction; muscle contraction; cation transport; transport
CHST14dermatan sulfate proteoglycan metabolic process; carbohydrate biosynthetic process
CHST15hexose biosynthetic process
CHST2multicellular organismal development; metabolic process; inflammatory response; sulfur compound metabolic process; carbohydrate metabolic process; N-acetylglucosamine metabolic process
CHST3positive regulation of cellular component movement; peripheral nervous system axon regeneration; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; T cell homeostasis; sulfur compound metabolic process
CHST4protein sulfation; N-acetylglucosamine metabolic process; carbohydrate metabolic process; sulfur compound metabolic process; cellular component movement; cell-cell signaling; cell adhesion; immune response; inflammatory response
CHST5carbohydrate metabolic process; sulfur compound metabolic process; protein sulfation; N-acetylglucosamine metabolic process
CHST6keratan sulfate biosynthetic process; sulfur compound metabolic process; N-acetylglucosamine metabolic process; carbohydrate metabolic process
CHST8proteoglycan biosynthetic process; sulfur compound metabolic process; central nervous system development; carbohydrate biosynthetic process; hormone biosynthetic process
CHST9proteoglycan biosynthetic process; hormone biosynthetic process; glycosaminoglycan metabolic process; carbohydrate biosynthetic process; metabolic process; sulfur compound metabolic process
CHSY1negative regulation of ossification; response to nutrient levels; chondroitin sulfate biosynthetic process
CHSY3-
CHUKpositive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 4 signaling pathway; fibroblast growth factor receptor signaling pathway; anatomical structure morphogenesis; osteoclast differentiation; nucleotide-binding oligomerization domain containing signaling pathway; mammary gland alveolus development; mammary gland epithelial cell proliferation; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; response to virus; TRIF-dependent toll-like receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; odontogenesis of dentin-containing tooth; innate immune response; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; T cell receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; immune response; morphogenesis of an epithelial sheet; toll-like receptor signaling pathway; MyD88-dependent toll-like recep
CIART-
CIB2integrin-mediated signaling pathway
CIB3-
CICregulation of transcription, DNA-dependent
CIDEBinduction of apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; apoptotic process
CIITAnegative regulation of collagen biosynthetic process; interferon-gamma-mediated signaling pathway; response to antibiotic; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of MHC class II biosynthetic process; positive regulation of MHC class I biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; immune response; cytokine-mediated signaling pathway; response to interferon-gamma
CILPnegative regulation of insulin-like growth factor receptor signaling pathway
CILP2-
CIPC-
CIR1mRNA processing; regulation of transcription, DNA-dependent; RNA splicing; negative regulation of transcription, DNA-dependent
CIRBPresponse to cold; response to UV; negative regulation of translation; stress granule assembly; positive regulation of translation; mRNA stabilization
CITspermatogenesis; cytokinesis; cell cycle; mitosis; mitotic metaphase/anaphase transition; multicellular organismal development; dendrite development; nervous system development; cell differentiation; mitotic sister chromatid segregation; cell cycle cytokinesis; intracellular signal transduction; generation of neurons; negative regulation of dendrite morphogenesis; cell division
CKAP2cytokinesis after mitosis; positive regulation of transcription from RNA polymerase II promoter; cell cycle; apoptotic process
CKAP2L-
CKAP5mitotic cell cycle; spindle organization; establishment or maintenance of microtubule cytoskeleton polarity; mitotic prometaphase; RNA transport; cell division; centrosome organization; M phase of mitotic cell cycle; G2/M transition of mitotic cell cycle
CKMT2muscle contraction; creatine metabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process
CLASRPRNA splicing; mRNA processing
CLCA1calcium ion transport; chloride transport; cellular response to hypoxia; ion transport; transport
CLCA2ion transmembrane transport; cell adhesion; chloride transport; transport
CLCA4transport; chloride transport
CLCC1-
CLCF1negative regulation of apoptotic process; positive regulation of astrocyte differentiation; positive regulation of isotype switching to IgE isotypes; negative regulation of neuron apoptosis; positive regulation of immunoglobulin production; cell surface receptor signaling pathway; JAK-STAT cascade; positive regulation of cell proliferation; cytokine-mediated signaling pathway; B cell differentiation; positive regulation of B cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein
CLCN1transport; ion transport; chloride transport; muscle contraction; neuronal action potential propagation; transmembrane transport
CLCN3transport; transmembrane transport; endosomal lumen acidification; regulation of pH; chloride transport; ion transport
CLCN4transport; ion transport; chloride transport; transmembrane transport
CLCN5transport; ion transport; chloride transport; endocytosis; excretion; transmembrane transport
CLCN6cell volume homeostasis; transmembrane transport; signal transduction; chloride transport; ion transport
CLCN7ion transport; chloride transport; response to pH; transmembrane transport; transport
CLDN1cell adhesion; interspecies interaction between organisms; calcium-independent cell-cell adhesion
CLDN11calcium-independent cell-cell adhesion; axon ensheathment; spermatogenesis; cell adhesion
CLDN14protein complex assembly; calcium-independent cell-cell adhesion; cell junction assembly; cell-cell junction organization; tight junction assembly
CLDN15calcium-independent cell-cell adhesion; cell junction assembly; cell-cell junction organization; tight junction assembly
CLDN16excretion; cellular metal ion homeostasis; ion transport; calcium-independent cell-cell adhesion; magnesium ion transport
CLDN2calcium-independent cell-cell adhesion
CLDN3calcium-independent cell-cell adhesion; response to hypoxia
CLDN5calcium-independent cell-cell adhesion
CLDN7calcium-independent cell-cell adhesion
CLDN8calcium-independent cell-cell adhesion
CLDND1-
CLEC10Ainnate immune response; endocytosis
CLEC12A-
CLEC12B-
CLEC14A-
CLEC1Adefense response; cell surface receptor signaling pathway
CLEC2B-
CLEC4Acell surface receptor signaling pathway; innate immune response; cell adhesion
CLEC4Epositive regulation of cytokine secretion; immune response
CLEC6Apositive regulation of I-kappaB kinase/NF-kappaB cascade; innate immune response; positive regulation of cytokine secretion; defense response to fungus
CLECL1-
CLGNbinding of sperm to zona pellucida; single fertilization; protein complex assembly; protein folding
CLHC1-
CLIC2signal transduction; chloride transport; ion transport; transport
CLIC3ion transport; chloride transport; signal transduction
CLIC4cell differentiation; establishment or maintenance of apical/basal cell polarity; negative regulation of cell migration; keratinocyte differentiation; chloride transport; ion transport; regulation of cytoskeleton organization; cellular response to calcium ion
CLIC6ion transport
CLIP1mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle; positive regulation of microtubule polymerization; mitosis; transport; microtubule bundle formation
CLIP2-
CLIP4-
CLK2protein phosphorylation; response to ionizing radiation; regulation of RNA splicing; negative regulation of gluconeogenesis; protein autophosphorylation
CLLU1-
CLMN-
CLMP-
CLOCKentrainment of circadian clock; circadian rhythm; photoperiodism; DNA damage checkpoint; regulation of transcription from RNA polymerase II promoter; signal transduction; circadian regulation of gene expression; positive regulation of transcription from RNA polymerase II promoter; cellular response to ionizing radiation
CLPBcellular response to heat
CLPTM1multicellular organismal development; regulation of T cell differentiation in thymus; cell differentiation
CLPTM1Lapoptotic process
CLRN1sensory perception of sound; photoreceptor cell maintenance; response to stimulus; sensory perception of light stimulus; equilibrioception
CLRN3-
CLSPNDNA damage checkpoint; DNA replication; mitotic cell cycle DNA replication checkpoint; activation of protein kinase activity; G2/M transition DNA damage checkpoint; peptidyl-serine phosphorylation; cell cycle; cellular component disassembly involved in apoptosis; apoptotic process; DNA repair; cell cycle checkpoint
CLSTN2homophilic cell adhesion; cell adhesion
CLSTN3cell adhesion; homophilic cell adhesion
CLTBintracellular protein transport; vesicle-mediated transport
CLTCpost-Golgi vesicle-mediated transport; nerve growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; transferrin transport; receptor internalization; vesicle-mediated transport; cellular membrane organization; axon guidance; epidermal growth factor receptor signaling pathway; mitosis; receptor-mediated endocytosis; intracellular protein transport
CLUAP1-
CLVS2lysosome organization
CLYBLcellular aromatic compound metabolic process
CMA1regulation of inflammatory response; proteolysis; interleukin-1 beta biosynthetic process
CMASlipopolysaccharide biosynthetic process
CMBL-
CMPK2pyrimidine nucleotide biosynthetic process; dTDP biosynthetic process; cellular response to lipopolysaccharide
CMTM1chemotaxis
CMTR1mRNA capping; mRNA methylation
CMTR2-
CNBD2-
CNBPpositive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cholesterol biosynthetic process; positive regulation of cell proliferation; regulation of transcription, DNA-dependent
CNDP1proteolysis; metabolic process
CNFNkeratinization
CNGA1transmembrane transport; response to stimulus; visual perception; ion transport; transport
CNGA2response to stimulus; sensory perception of smell; ion transmembrane transport
CNGA3transport; ion transport; cation transport; signal transduction; response to stimulus; visual perception; ion transmembrane transport; retinal cone cell development; transmembrane transport
CNGB1transport; response to stimulus; photoreceptor cell maintenance; sensory perception of smell; phototransduction; ion transport; visual perception
CNGB3ion transmembrane transport; visual perception; response to stimulus; signal transduction; cation transport; transport
CNIH2regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; synaptic transmission, glutamatergic; intracellular signal transduction; regulation of membrane potential; localization within membrane
CNIH4intracellular signal transduction
CNKSR1Rho protein signal transduction; Ras protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
CNKSR2regulation of signal transduction
CNKSR3negative regulation of ERK1 and ERK2 cascade; negative regulation of peptidyl-serine phosphorylation; positive regulation of sodium ion transport; regulation of signal transduction
CNN1regulation of smooth muscle contraction; actomyosin structure organization
CNN2negative regulation of cell migration; hemopoiesis; positive regulation of gene expression; cytoskeleton organization; actomyosin structure organization; regulation of actin filament-based process; wound healing; regulation of cell proliferation; negative regulation of phagocytosis; cellular response to mechanical stimulus
CNN3actomyosin structure organization; smooth muscle contraction; negative regulation of ATPase activity
CNNM3ion transport
CNNM4biomineral tissue development; response to stimulus; ion transport; visual perception
CNOT1nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; regulation of transcription, DNA-dependent; gene expression; RNA metabolic process; mRNA metabolic process
CNOT10nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; RNA metabolic process; gene expression; mRNA metabolic process
CNOT11-
CNOT2nuclear-transcribed mRNA poly(A) tail shortening; gene expression; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; regulation of transcription from RNA polymerase II promoter; mRNA metabolic process; RNA metabolic process
CNOT4protein autoubiquitination; mRNA metabolic process; RNA metabolic process; gene expression; regulation of transcription, DNA-dependent; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
CNPmicrotubule cytoskeleton organization; synaptic transmission; axonogenesis; adult locomotory behavior; cyclic nucleotide catabolic process; response to toxin; RNA metabolic process
CNPPD1regulation of cyclin-dependent protein kinase activity
CNPY2-
CNPY3innate immune response
CNPY4-
CNR1response to morphine; negative regulation of ion transport; memory; response to ethanol; negative regulation of action potential; negative regulation of blood pressure; positive regulation of blood pressure; regulation of insulin secretion; negative regulation of nitric-oxide synthase activity; regulation of synaptic transmission, glutamatergic; maternal process involved in female pregnancy; regulation of feeding behavior; regulation of penile erection; response to cocaine; positive regulation of neuron projection development; behavior; response to nutrient; aging; regulation of lipid metabolic process; sensory perception of pain; positive regulation of fever generation; negative regulation of fatty acid beta-oxidation; regulation of synaptic transmission, GABAergic; spermatogenesis; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; response to stress; positive regulation of acute inflammatory response to antigenic stimulus; r
CNR2G-protein signaling, coupled to cyclic nucleotide second messenger; immune response; behavior; sensory perception of pain; negative regulation of synaptic transmission, GABAergic; response to lipopolysaccharide; negative regulation of mast cell activation; negative regulation of action potential; negative regulation of inflammatory response; negative regulation of nitric-oxide synthase activity; response to amphetamine
CNRIP1-
CNSTnegative regulation of phosphatase activity; positive regulation of Golgi to plasma membrane protein transport
CNTFpositive regulation of cell proliferation; membrane hyperpolarization; regulation of resting membrane potential; signal transduction; multicellular organismal development; nervous system development; positive regulation of axon regeneration; positive regulation of phosphatidylinositol 3-kinase cascade; cell differentiation; positive regulation of cell growth; growth; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of MAPK cascade; negative regulation of neuron apoptosis; neuroprotection; positive regulation of JAK-STAT cascade; negative regulation of photoreceptor cell differentiation; regulation of retinal cell programmed cell death; positive regulation of hormone secretion; astrocyte activation; muscle organ morphogenesis; neuron development; ciliary neurotrophic factor-mediated signaling pathway
CNTFRsuckling behavior; brainstem development; signal transduction; nervous system development; sex differentiation; positive regulation of cell proliferation; negative regulation of neuron apoptosis; skeletal muscle organ development; ciliary neurotrophic factor-mediated signaling pathway
CNTLN-
CNTN1cell adhesion; Notch signaling pathway; axon guidance
CNTN2microtubule cytoskeleton organization; establishment of protein localization to juxtaparanode region of axon; positive regulation of adenosine receptor signaling pathway; regulation of astrocyte differentiation; regulation of neuronal synaptic plasticity; negative regulation of neuron differentiation; clustering of voltage-gated potassium channels; neuron projection development; neuron migration; cell adhesion; cell-matrix adhesion; axon guidance; axonal fasciculation; learning; adult walking behavior; regulation of cell morphogenesis involved in differentiation; positive regulation of protein processing; cerebral cortex GABAergic interneuron migration; central nervous system myelination; regulation of axon diameter; cellular protein localization; receptor internalization
CNTN3cell adhesion; nervous system development
CNTN4brain development; nervous system development; axonogenesis; axon guidance; axonal fasciculation; neuron projection development; negative regulation of neuron differentiation; regulation of synaptic plasticity; cell adhesion; neuron cell-cell adhesion
CNTN6cell adhesion; Notch signaling pathway; axon guidance; central nervous system development
CNTNAP1neuromuscular process controlling posture; signal transduction; cell adhesion; cytoskeleton organization; protein localization to paranode region of axon; axon guidance; neuromuscular process controlling balance; neuron projection morphogenesis; axon cargo transport; paranodal junction assembly
CNTNAP2transmission of nerve impulse; striatum development; neuron recognition; behavior; brain development; protein localization to juxtaparanode region of axon; limbic system development; thalamus development; cerebral cortex development; vocalization behavior; neuron projection development; cell adhesion; superior temporal gyrus development; signal transduction; cellular protein localization; clustering of voltage-gated potassium channels
CNTRLmitotic cell cycle; G2/M transition of mitotic cell cycle; cell division
CNTROBcentrosome separation; cytokinesis; cell cycle; centriole replication
COA4-
COA6-
COA7-
COASYcoenzyme biosynthetic process; coenzyme A biosynthetic process; pantothenate metabolic process; small molecule metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; biosynthetic process
COBLneural tube closure
COBLL1-
COCHsensory perception of sound
COG1intra-Golgi vesicle-mediated transport; Golgi organization; protein transport
COG2oligosaccharide biosynthetic process; protein glycosylation; intracellular protein transport; intra-Golgi vesicle-mediated transport; Golgi organization; protein transport
COG4protein transport; Golgi vesicle prefusion complex stabilization; Golgi organization; retrograde vesicle-mediated transport, Golgi to ER
COG5protein transport; intra-Golgi vesicle-mediated transport
COG6intra-Golgi vesicle-mediated transport; protein transport
COG7protein stabilization; retrograde vesicle-mediated transport, Golgi to ER; protein localization in Golgi apparatus; protein localization to organelle; protein glycosylation; intracellular protein transport
COG8protein transport
COL10A1skeletal system development
COL11A1embryonic skeletal system morphogenesis; cartilage condensation; ossification; chondrocyte development; heart morphogenesis; proteoglycan metabolic process; cell adhesion; visual perception; sensory perception of sound; extracellular matrix organization; collagen fibril organization; inner ear morphogenesis; detection of mechanical stimulus involved in sensory perception of sound; ventricular cardiac muscle tissue morphogenesis
COL12A1collagen fibril organization; cell adhesion; skeletal system development
COL14A1extracellular matrix organization; cell-cell adhesion; collagen fibril organization
COL15A1cell differentiation; multicellular organismal development; signal transduction; cell adhesion; angiogenesis
COL16A1cellular response to amino acid stimulus; female pregnancy; integrin-mediated signaling pathway; cell adhesion
COL17A1cell-matrix adhesion; epidermis development; hemidesmosome assembly; cell junction assembly
COL18A1negative regulation of cell proliferation; organ morphogenesis; visual perception; cell adhesion
COL19A1skeletal system development; cell adhesion; multicellular organismal development; muscle organ development; skeletal muscle tissue development; cell-cell adhesion; cell differentiation; extracellular matrix organization
COL1A1response to inorganic substance; sensory perception of sound; visual perception; blood coagulation; response to nutrient; axon guidance; endochondral ossification; intramembranous ossification; osteoblast differentiation; blood vessel development; embryonic skeletal system development; skeletal system development; negative regulation of cell-substrate adhesion; leukocyte migration; response to cAMP; face morphogenesis; bone trabecula formation; cartilage development involved in endochondral bone morphogenesis; protein heterotrimerization; cellular response to amino acid stimulus; cellular response to mechanical stimulus; cellular response to retinoic acid; cellular response to growth factor stimulus; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of epithelial to mesenchymal transition; protein transport; platelet activation; collagen fibril organization; positive regulation of cell migration; response to corticosteroid
COL22A1cell adhesion
COL23A1protein homotrimerization
COL24A1cell adhesion
COL25A1-
COL27A1cell adhesion
COL28A1cell adhesion
COL2A1sensory perception of sound; cartilage development involved in endochondral bone morphogenesis; bone development; embryonic skeletal joint morphogenesis; limb bud formation; palate development; cartilage development; negative regulation of apoptotic process; inner ear morphogenesis; notochord development; collagen fibril organization; regulation of gene expression; otic vesicle development; visual perception; central nervous system development; axon guidance; proteoglycan metabolic process; heart morphogenesis; chondrocyte differentiation; endochondral ossification; tissue homeostasis; ossification; cartilage condensation; skeletal system development
COL3A1skeletal system development; cellular response to amino acid stimulus; negative regulation of immune response; digestive tract development; skin development; fibril organization; wound healing; response to cytokine stimulus; collagen biosynthetic process; collagen fibril organization; platelet activation; peptide cross-linking; response to radiation; heart development; axon guidance; integrin-mediated signaling pathway; transforming growth factor beta receptor signaling pathway; cell-matrix adhesion; blood vessel development
COL4A1neuromuscular junction development; epithelial cell differentiation; cellular response to amino acid stimulus; axon guidance; angiogenesis
COL4A2transcription, DNA-dependent; axon guidance; negative regulation of angiogenesis; extracellular matrix organization; cellular response to transforming growth factor beta stimulus
COL4A3glomerular basement membrane development; negative regulation of angiogenesis; response to glucose stimulus; negative regulation of cell proliferation; cell proliferation; blood circulation; sensory perception of sound; axon guidance; cell surface receptor signaling pathway; cell adhesion; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis
COL4A3BPER to Golgi ceramide transport; sphingolipid biosynthetic process; response to endoplasmic reticulum stress; small molecule metabolic process; lipid homeostasis; mitochondrion morphogenesis; cell proliferation; immune response; signal transduction; endoplasmic reticulum organization; muscle contraction; lipid transport; transport; ceramide metabolic process; sphingolipid metabolic process; protein phosphorylation; heart morphogenesis; in utero embryonic development; cell morphogenesis
COL4A4axon guidance; glomerular basement membrane development
COL4A5axon guidance
COL4A6cell adhesion; extracellular matrix organization; cellular response to amino acid stimulus
COL5A1skin development; regulation of cellular component organization; eye morphogenesis; integrin biosynthetic process; fibril organization; wound healing, spreading of epidermal cells; collagen biosynthetic process; cell migration; axon guidance; cell adhesion; heart morphogenesis; blood vessel development; collagen fibril organization
COL5A2collagen fibril organization; cellular response to amino acid stimulus; eye morphogenesis; skin development; axon guidance; skeletal system development
COL5A3cell adhesion; skin development; collagen fibril organization; cell-matrix adhesion
COL6A1cell adhesion; axon guidance; protein heterotrimerization; cellular response to amino acid stimulus
COL6A2extracellular matrix organization; protein heterotrimerization; cell-cell adhesion; response to glucose stimulus; axon guidance
COL6A3cell adhesion; axon guidance; muscle organ development; response to glucose stimulus
COL7A1cell adhesion; epidermis development
COL8A2cell-cell adhesion; epithelial cell proliferation; camera-type eye morphogenesis; extracellular matrix organization; angiogenesis
COL9A1tissue homeostasis; chondrocyte differentiation; growth plate cartilage development; cell adhesion; axon guidance; organ morphogenesis
COL9A2skeletal system development; axon guidance
COLEC10-
COLGALT2-
COLQneurotransmitter catabolic process; asymmetric protein localization; acetylcholine catabolic process in synaptic cleft
COMMD9-
COMPgrowth plate cartilage development; apoptotic process; anti-apoptosis; cell adhesion; organ morphogenesis; limb development; skeletal system development
COPAcellular membrane organization; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; pancreatic juice secretion; vesicle-mediated transport; COPI coating of Golgi vesicle
COPB1interspecies interaction between organisms; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; intra-Golgi vesicle-mediated transport; cellular membrane organization; COPI coating of Golgi vesicle; vesicle-mediated transport
COPB2retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; COPI coating of Golgi vesicle; vesicle-mediated transport; cellular membrane organization; intra-Golgi vesicle-mediated transport
COPG1retrograde vesicle-mediated transport, Golgi to ER; cellular membrane organization; vesicle-mediated transport; COPI coating of Golgi vesicle; intracellular protein transport
COPS2cullin deneddylation; signal transduction; transcription from RNA polymerase II promoter
COPS3in utero embryonic development; signal transduction; response to light stimulus; cullin deneddylation
COPS4cullin deneddylation
COPS5regulation of JNK cascade; translational initiation; translation; transcription from RNA polymerase II promoter; proteolysis; cullin deneddylation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; protein deneddylation
COPS6cullin deneddylation; interspecies interaction between organisms
COPS7Acullin deneddylation
COPS7Bcullin deneddylation
COPS8cullin deneddylation
COPZ1vesicle-mediated transport; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; intra-Golgi vesicle-mediated transport; cellular membrane organization; COPI coating of Golgi vesicle
COQ10A-
COQ10B-
COQ3metabolic process; ubiquinone biosynthetic process; glycerol metabolic process
COQ6ubiquinone biosynthetic process
CORINpeptide hormone processing; regulation of systemic arterial blood pressure by atrial natriuretic peptide; proteolysis
CORO1AT cell homeostasis; cell-substrate adhesion; response to cytokine stimulus; regulation of actin filament polymerization; positive regulation of T cell proliferation; uropod organization; innate immune response; leukocyte chemotaxis; positive regulation of cell migration; actin cytoskeleton organization; regulation of cell shape; actin filament organization; cellular component movement; phagocytosis; calcium ion transport; homeostasis of number of cells within a tissue; positive chemotaxis; negative regulation of actin nucleation; phagolysosome assembly
CORO1Bactin cytoskeleton organization
CORO2Aintracellular signal transduction; actin cytoskeleton organization
CORO2Bactin cytoskeleton organization
CORO6actin cytoskeleton organization
COX15respiratory gaseous exchange; oxidation-reduction process; cellular respiration; respiratory chain complex IV assembly; mitochondrial electron transport, cytochrome c to oxygen; heme a biosynthetic process
COX7B2-
COX8C-
CPtransmembrane transport; ion transport; cellular iron ion homeostasis; copper ion transport
CPA1proteolysis
CPA2vacuolar protein catabolic process; proteolysis
CPA5metabolic process; proteolysis
CPA6proteolysis
CPAMD8-
CPB1proteolysis
CPB2proteolysis; blood coagulation; metabolic process; response to heat; response to drug; negative regulation of fibrinolysis
CPDproteolysis; cellular response to interleukin-2
CPEinsulin processing; cardiac left ventricle morphogenesis; protein modification process; neuropeptide signaling pathway; metabolic process; protein localization in membrane; proteolysis
CPEB1regulation of translation; mRNA processing
CPEB2regulation of translation
CPEB3-
CPED1-
CPN1proteolysis; metabolic process; response to glucocorticoid stimulus
CPN2protein stabilization; regulation of catalytic activity
CPNE1lipid metabolic process; vesicle-mediated transport
CPNE2-
CPNE3lipid metabolic process; vesicle-mediated transport
CPNE4-
CPNE5-
CPNE7lipid metabolic process; transport
CPNE8-
CPOproteolysis
CPPED1-
CPQproteolysis; peptide metabolic process; tissue regeneration
CPS1cellular response to oleic acid; response to dexamethasone stimulus; cellular response to glucagon stimulus; cellular response to cAMP; glycogen catabolic process; response to amino acid stimulus; small molecule metabolic process; cellular response to fibroblast growth factor stimulus; positive regulation of vasodilation; nitric oxide metabolic process; response to steroid hormone stimulus; homocysteine metabolic process; anion homeostasis; response to growth hormone stimulus; hepatocyte differentiation; urea cycle; carbamoyl phosphate biosynthetic process; response to starvation; glutamine catabolic process; nitrogen compound metabolic process; midgut development; response to toxin; response to zinc ion; citrulline biosynthetic process; triglyceride catabolic process; response to food; response to lipopolysaccharide; cellular nitrogen compound metabolic process; response to drug
CPSF1nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA 3'-end processing; gene expression; RNA splicing; mRNA export from nucleus; mRNA processing; mRNA cleavage; mRNA polyadenylation; termination of RNA polymerase II transcription
CPSF2RNA splicing; gene expression; mRNA export from nucleus; histone mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription; nuclear mRNA splicing, via spliceosome; mRNA 3'-end processing; transcription from RNA polymerase II promoter
CPSF3mRNA export from nucleus; termination of RNA polymerase II transcription; mRNA polyadenylation; mRNA cleavage; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA 3'-end processing; RNA splicing; gene expression; histone mRNA 3'-end processing; mRNA processing
CPSF4modification by virus of host mRNA processing; interspecies interaction between organisms; viral infectious cycle; modulation by virus of host cellular process; virus-host interaction; mRNA processing
CPSF6mRNA polyadenylation; mRNA processing; protein tetramerization
CPSF7protein tetramerization; mRNA 3'-end processing; gene expression; RNA splicing; mRNA processing; nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; termination of RNA polymerase II transcription
CPT1Along-chain fatty acid metabolic process; protein homooligomerization; regulation of insulin secretion; regulation of fatty acid oxidation; small molecule metabolic process; cellular lipid metabolic process; eating behavior; response to drug; positive regulation of fatty acid beta-oxidation; response to organic cyclic compound; carnitine shuttle; transport; triglyceride metabolic process; fatty acid beta-oxidation; glucose metabolic process
CPT1Bfatty acid beta-oxidation; fatty acid metabolic process; transport; carnitine shuttle; cellular lipid metabolic process; small molecule metabolic process; regulation of fatty acid oxidation
CPT1Cfatty acid metabolic process; lipid metabolic process; carnitine metabolic process
CPT2regulation of fatty acid oxidation; fatty acid metabolic process; fatty acid beta-oxidation; transport; carnitine shuttle; cellular lipid metabolic process; small molecule metabolic process
CPTP-
CPXCR1-
CPXM1cell adhesion; proteolysis
CPXM2cell adhesion; proteolysis
CPZproteolysis; Wnt receptor signaling pathway
CR2immune response; complement activation, classical pathway; complement receptor mediated signaling pathway; innate immune response
CRACR2Bstore-operated calcium entry
CRATsmall molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; transport; fatty acid metabolic process
CRB1establishment or maintenance of cell polarity; cell-cell signaling; cellular membrane organization; eye photoreceptor cell development
CRB2-
CRBNproteolysis; protein ubiquitination; positive regulation of protein homodimerization activity; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ion transmembrane transport; negative regulation of protein homooligomerization
CREB3regulation of cell proliferation; interspecies interaction between organisms; negative regulation of cell cycle; positive regulation of transcription, DNA-dependent; induction of positive chemotaxis; positive regulation of calcium ion transport; positive regulation of cell migration; reactivation of latent virus; chemotaxis; transcription, DNA-dependent
CREB3L3response to unfolded protein
CREB5transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent
CREBBPnegative regulation of transcription from RNA polymerase II promoter; protein complex assembly; regulation of transcription, DNA-dependent; response to hypoxia; histone acetylation; signal transduction; Notch signaling pathway; cell proliferation; regulation of smoothened signaling pathway; gene expression; germ-line stem cell maintenance; regulation of S phase; homeostatic process; embryonic digit morphogenesis; cellular lipid metabolic process; small molecule metabolic process; interspecies interaction between organisms; innate immune response; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; N-terminal peptidyl-lysine acetylation
CREBRF-
CREBZFtranscription, DNA-dependent; response to virus; negative regulation of gene expression, epigenetic; negative regulation of transcription, DNA-dependent; regulation of sequence-specific DNA binding transcription factor activity
CREMcell differentiation; spermatogenesis; multicellular organismal development; signal transduction; regulation of transcription, DNA-dependent
CRHR2G-protein signaling, coupled to cAMP nucleotide second messenger; cellular response to corticotropin-releasing hormone stimulus
CRIM1nervous system development; insulin-like growth factor receptor signaling pathway; regulation of cell growth
CRIPAKregulation of cytoskeleton organization; response to estrogen stimulus; negative regulation of protein kinase activity; negative regulation of intracellular estrogen receptor signaling pathway
CRIPTcytoplasmic microtubule organization; establishment of protein localization
CRISP2-
CRISPLD2-
CRMP1nucleobase-containing compound metabolic process; pyrimidine base catabolic process; nervous system development; axon guidance
CRNKL1nuclear mRNA splicing, via spliceosome; RNA splicing; RNA processing; spliceosome assembly
CROCCcell cycle; protein localization; cell projection organization; centrosome organization
CROTfatty acid beta-oxidation using acyl-CoA oxidase; small molecule metabolic process; transport; fatty acid beta-oxidation; fatty acid metabolic process; cellular lipid metabolic process
CRTAC1-
CRTAMpositive regulation of cytokine secretion; T cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; detection of stimulus; activated T cell proliferation; regulation of immune response; detection of tumor cell; positive regulation of natural killer cell mediated cytotoxicity; cell recognition
CRTC1regulation of transcription, DNA-dependent; positive regulation of CREB transcription factor activity; interspecies interaction between organisms; positive regulation of transcription from RNA polymerase II promoter; protein homotetramerization
CRTC2protein homotetramerization; gluconeogenesis; regulation of transcription, DNA-dependent; interspecies interaction between organisms; glucose homeostasis; positive regulation of CREB transcription factor activity
CRTC3protein homotetramerization; interspecies interaction between organisms; positive regulation of CREB transcription factor activity; regulation of transcription, DNA-dependent
CRXpositive regulation of transcription from RNA polymerase II promoter; retina development in camera-type eye; response to stimulus; organ morphogenesis; visual perception; multicellular organismal development; regulation of transcription, DNA-dependent
CRY2negative regulation of transcription from RNA polymerase II promoter; photoreactive repair; DNA repair; regulation of transcription, DNA-dependent; protein import into nucleus; blue light signaling pathway; protein-chromophore linkage; regulation of circadian rhythm; response to stimulus
CRYABprotein folding; protein homooligomerization; negative regulation of intracellular transport; muscle contraction; anti-apoptosis
CRYBA2-
CRYGAlens development in camera-type eye; visual perception; eye development
CRYGDvisual perception; cellular response to reactive oxygen species; response to stimulus
CRYGSmorphogenesis of an epithelium; lens development in camera-type eye
CRYL1fatty acid metabolic process
CRYZvisual perception; xenobiotic catabolic process; protein homotetramerization
CSsmall molecule metabolic process; cellular carbohydrate metabolic process; citrate metabolic process; tricarboxylic acid cycle; acetyl-CoA metabolic process; oxaloacetate metabolic process; carbohydrate metabolic process
CSDC2mRNA processing; histone mRNA 3'-end processing; regulation of transcription, DNA-dependent
CSDE1male gonad development; regulation of transcription, DNA-dependent
CSF1positive regulation of multicellular organism growth; monocyte activation; odontogenesis; positive regulation of odontogenesis of dentin-containing tooth; positive regulation of macrophage differentiation; positive regulation of monocyte differentiation; positive regulation of osteoclast differentiation; positive regulation of protein kinase activity; positive regulation of Ras protein signal transduction; homeostasis of number of cells within a tissue; branching involved in mammary gland duct morphogenesis; mammary gland fat development; mammary duct terminal end bud growth; innate immune response; positive regulation of cellular protein metabolic process; positive regulation of cell-matrix adhesion; positive regulation of mononuclear cell proliferation; developmental process involved in reproduction; inflammatory response; cell proliferation; positive regulation of cell proliferation; positive regulation of gene expression; regulation of macrophage derived foam cell differentiation; hemopoiesis; cell differ
CSF1Rpositive regulation of tyrosine phosphorylation of Stat3 protein; innate immune response; regulation of bone resorption; cell-cell junction maintenance; phosphatidylinositol metabolic process; protein autophosphorylation; phosphatidylinositol-mediated signaling; mammary gland duct morphogenesis; positive regulation of protein tyrosine kinase activity; positive regulation of ERK1 and ERK2 cascade; cellular response to cytokine stimulus; positive regulation of protein serine/threonine kinase activity; positive regulation of chemokine secretion; positive regulation of cell motility; regulation of actin cytoskeleton reorganization; macrophage differentiation; ruffle organization; positive regulation of protein phosphorylation; inflammatory response; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; multicellular organismal development; cell proliferation; positive regulation of cell proliferation; regulation of cell shape; peptidyl-tyrosine phosphorylation; cytokine-mediated s
CSF2RBsignal transduction; respiratory gaseous exchange; cellular response to interleukin-3; interleukin-5-mediated signaling pathway
CSF3immune response; multicellular organismal development; positive regulation of cell proliferation; cytokine-mediated signaling pathway; granulocyte differentiation
CSF3Rdefense response; cell adhesion; signal transduction
CSGALNACT2dermatan sulfate proteoglycan biosynthetic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
CSKprotein phosphorylation; epidermal growth factor receptor signaling pathway; blood coagulation; negative regulation of cell proliferation; platelet activation; T cell costimulation; peptidyl-tyrosine dephosphorylation; T cell receptor signaling pathway
CSMD2-
CSMD3-
CSN2negative regulation of catalytic activity; calcium ion transport
CSN3lactation
CSNK1DG2/M transition of mitotic cell cycle; mitotic cell cycle; DNA repair; positive regulation of protein phosphorylation; protein phosphorylation; signal transduction; Wnt receptor signaling pathway; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; circadian regulation of gene expression; rhythmic process; spindle assembly; positive regulation of canonical Wnt receptor signaling pathway; regulation of circadian rhythm
CSNK1Epositive regulation of canonical Wnt receptor signaling pathway; cellular protein localization; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of Wnt receptor signaling pathway; signal transduction; protein phosphorylation; DNA repair; mitotic cell cycle; G2/M transition of mitotic cell cycle
CSNK1G2sphingolipid metabolic process; protein phosphorylation; signal transduction; Wnt receptor signaling pathway; sphingolipid biosynthetic process; small molecule metabolic process; protein autophosphorylation
CSNK2A2regulation of transcription, DNA-dependent; apoptotic process; axon guidance; Wnt receptor signaling pathway; regulation of cell cycle; mitotic cell cycle spindle checkpoint
CSPG4neuron remodeling; positive regulation of peptidyl-tyrosine phosphorylation; tissue remodeling; neuron fate commitment; intracellular signal transduction; cell differentiation; multicellular organismal development; angiogenesis
CSPP1positive regulation of cell cycle cytokinesis; positive regulation of cell division
CSRNP3negative regulation of phosphatase activity; positive regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter
CST9L-
CSTF2TmRNA processing
CSTF3mRNA 3'-end processing; gene expression; RNA splicing; mRNA processing; RNA processing; mRNA cleavage; mRNA polyadenylation; termination of RNA polymerase II transcription; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome
CSTL1-
CTAGE5positive regulation of catalytic activity
CTBP1oxidation-reduction process; negative regulation of transcription from RNA polymerase II promoter; protein phosphorylation; negative regulation of cell proliferation; viral genome replication; cell differentiation; positive regulation of histone deacetylation; regulation of transcription by chromatin organization; negative regulation of histone acetylation; interspecies interaction between organisms; negative regulation of transcription, DNA-dependent; white fat cell differentiation; regulation of cell cycle; negative regulation of histone H4 acetylation
CTBP2viral genome replication; negative regulation of cell proliferation; cell differentiation; negative regulation of transcription, DNA-dependent; oxidation-reduction process; white fat cell differentiation
CTBScarbohydrate metabolic process; chitin catabolic process; oligosaccharide catabolic process
CTC1telomere maintenance; positive regulation of DNA replication
CTCFregulation of gene expression by genetic imprinting; chromosome segregation; maintenance of DNA methylation; positive regulation of gene expression; chromatin modification; nucleosome positioning; regulation of histone methylation; regulation of histone acetylation; regulation of gene expression, epigenetic; regulation of molecular function, epigenetic; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of centromeric sister chromatid cohesion
CTCFLhistone methylation; DNA methylation involved in gamete generation; chromatin modification; positive regulation of gene expression; cell cycle; regulation of gene expression by genetic imprinting; positive regulation of transcription, DNA-dependent; regulation of histone H3-K4 methylation
CTDNEP1protein dephosphorylation; protein localization to nucleus; positive regulation of triglyceride biosynthetic process; nuclear envelope organization
CTDSP1negative regulation of neuron differentiation; protein dephosphorylation; regulation of transcription from RNA polymerase II promoter; negative regulation of neurogenesis
CTDSPL2-
CTGFpositive regulation of cell death; response to fatty acid; positive regulation of ERK1 and ERK2 cascade; response to organic cyclic compound; small molecule metabolic process; cellular lipid metabolic process; response to peptide hormone stimulus; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to amino acid stimulus; intracellular signal transduction; response to anoxia; positive regulation of collagen biosynthetic process; response to estradiol stimulus; lung development; extracellular matrix constituent secretion; positive regulation of gene expression; organ senescence; response to glucose stimulus; response to wounding; epidermis development; positive regulation of cell proliferation; cell adhesion; DNA replication; positive regulation of protein phosphorylation; regulation of cell growth; positive regulation of JNK cascade; positive regulation of cell activation; response to mineralocorticoid stimulus; positive regulation of stress fiber assembly; cyto
CTHnegative regulation of cell growth; sulfur amino acid metabolic process; sulfur amino acid catabolic process; cysteine metabolic process; glutathione metabolic process; negative regulation of cell proliferation; cellular amino acid biosynthetic process; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; cysteine biosynthetic process; transsulfuration; cellular nitrogen compound metabolic process; small molecule metabolic process; protein homotetramerization; hydrogen sulfide biosynthetic process
CTHRC1establishment of planar polarity involved in neural tube closure; cell migration; positive regulation of protein binding; Wnt receptor signaling pathway, planar cell polarity pathway; inner ear receptor stereocilium organization; negative regulation of canonical Wnt receptor signaling pathway; cochlea morphogenesis
CTNNA1aging; odontogenesis of dentin-containing tooth; regulation of cell proliferation; adherens junction organization; cell junction assembly; axon regeneration; gap junction assembly; response to organic cyclic compound; male gonad development; response to estrogen stimulus; negative regulation of neuroblast proliferation; establishment or maintenance of cell polarity; muscle cell differentiation; negative regulation of apoptotic process; apical junction assembly; cell-cell junction organization; positive regulation of smoothened signaling pathway; positive regulation of muscle cell differentiation; cellular response to indole-3-methanol; cell adhesion; ovarian follicle development
CTNNA2cell-cell adhesion; axonogenesis; prepulse inhibition; regulation of synapse structural plasticity; positive regulation of muscle cell differentiation; brain morphogenesis; dendrite morphogenesis; muscle cell differentiation; radial glia guided migration of Purkinje cell; multicellular organismal development
CTNNA3cell-cell adhesion
CTNNAL1Rho protein signal transduction; cell adhesion
CTNNB1cell maturation; oviduct development; synaptic vesicle transport; thymus development; embryonic hindlimb morphogenesis; oocyte development; embryonic foregut morphogenesis; regulation of smooth muscle cell proliferation; negative regulation of oligodendrocyte differentiation; synapse organization; smooth muscle cell differentiation; positive regulation of muscle cell differentiation; determination of dorsal/ventral asymmetry; regulation of fibroblast proliferation; response to cadmium ion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of anti-apoptosis; regulation of angiogenesis; positive regulation of fibroblast growth factor receptor signaling pathway; negative regulation of osteoclast differentiation; positive regulation of osteoblast differentiation; positive regulation of endothelial cell differentiation; bone resorption; canonical Wnt receptor signaling p
CTNNBL1somatic diversification of immunoglobulins; positive regulation of apoptotic process
CTNND2morphogenesis of a branching structure; regulation of transcription, DNA-dependent; cell adhesion; neuron cell-cell adhesion; signal transduction; multicellular organismal development; learning; regulation of synaptic plasticity
CTPS1pyrimidine nucleotide biosynthetic process; nucleobase-containing compound metabolic process; CTP biosynthetic process; glutamine metabolic process; nucleobase-containing small molecule interconversion; response to drug; small molecule metabolic process; nucleobase-containing small molecule metabolic process
CTPS2pyrimidine nucleotide metabolic process; pyrimidine nucleotide biosynthetic process; glutamine metabolic process; nucleobase-containing small molecule interconversion; small molecule metabolic process; nucleobase-containing small molecule metabolic process
CTR9histone monoubiquitination; histone H2B ubiquitination
CTSAsmall molecule metabolic process; positive regulation of catalytic activity; intracellular protein transport; glycosphingolipid metabolic process; sphingolipid metabolic process; proteolysis
CTSBproteolysis; autophagy; cellular response to thyroid hormone stimulus; response to interleukin-4; negative regulation of cell death; regulation of catalytic activity; response to ethanol; response to peptide hormone stimulus; regulation of apoptotic process; response to amine stimulus; response to organic cyclic compound; response to glucose stimulus; response to mechanical stimulus; response to wounding; skeletal muscle tissue development
CTSDproteolysis; cell death
CTSEdigestion; proteolysis; antigen processing and presentation of exogenous peptide antigen via MHC class II
CTSWproteolysis; immune response
CTTN-
CTTNBP2brain development
CTTNBP2NL-
CTU2tRNA processing; tRNA thio-modification; tRNA wobble uridine modification
CUBNcholesterol metabolic process; steroid metabolic process; hemoglobin import; lipoprotein metabolic process; vitamin D metabolic process; lipoprotein transport; small molecule metabolic process; protein homotrimerization; response to nutrient; receptor-mediated endocytosis; lipid metabolic process; tissue homeostasis; in utero embryonic development; cobalamin transport
CUL2protein catabolic process; G1/S transition of mitotic cell cycle; ubiquitin-dependent protein catabolic process; cell cycle arrest; negative regulation of cell proliferation; induction of apoptosis by intracellular signals; interspecies interaction between organisms
CUL3cell morphogenesis; anaphase; proteasomal ubiquitin-dependent protein catabolic process; stress fiber assembly; negative regulation of Rho protein signal transduction; protein ubiquitination; cell migration; Wnt receptor signaling pathway; positive regulation of cell proliferation; mitotic anaphase; G1/S transition of mitotic cell cycle; cytokinesis; in utero embryonic development; trophectodermal cellular morphogenesis; cell cycle arrest; gastrulation; induction of apoptosis by intracellular signals; cyclin catabolic process
CUL4Aregulation of protein metabolic process; positive regulation of S phase of mitotic cell cycle; interspecies interaction between organisms; induction of apoptosis by intracellular signals; negative regulation of cell proliferation; regulation of mitotic cell cycle; cell cycle arrest; ubiquitin-dependent protein catabolic process; DNA repair; G1/S transition of mitotic cell cycle
CUL4Bcell cycle; ubiquitin-dependent protein catabolic process; DNA repair
CUL5calcium ion transmembrane transport; G1/S transition of mitotic cell cycle; ubiquitin-dependent protein catabolic process; response to osmotic stress; cell cycle arrest; cell proliferation; negative regulation of cell proliferation; induction of apoptosis by intracellular signals; viral reproduction; interspecies interaction between organisms; cytosolic calcium ion homeostasis
CUL7activation of signaling protein activity involved in unfolded protein response; ubiquitin-dependent protein catabolic process; proteolysis; vasculogenesis; interspecies interaction between organisms; endoplasmic reticulum unfolded protein response
CUL9ubiquitin-dependent protein catabolic process
CUTCprotein tetramerization; copper ion transport; copper ion homeostasis
CUX1lung development; negative regulation of transcription from RNA polymerase II promoter; retrograde transport, vesicle recycling within Golgi; regulation of transcription from RNA polymerase II promoter; transport; intra-Golgi vesicle-mediated transport; multicellular organismal development; auditory receptor cell differentiation
CUX2negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent
CUZD1hormone-mediated signaling pathway; trypsinogen activation; cell division; substrate-dependent cell migration, cell attachment to substrate; cell cycle; cell adhesion; cell proliferation
CWC27nuclear mRNA splicing, via spliceosome; protein folding
CWH43GPI anchor biosynthetic process
CXCL8induction of positive chemotaxis; signal transduction; cell cycle arrest; activation of signaling protein activity involved in unfolded protein response; immune response; inflammatory response; chemotaxis; cellular component movement; positive regulation of neutrophil chemotaxis; cellular response to tumor necrosis factor; cellular response to interleukin-1; cellular response to lipopolysaccharide; negative regulation of cell proliferation; embryonic digestive tract development; negative regulation of G-protein coupled receptor protein signaling pathway; regulation of retroviral genome replication; cellular response to fibroblast growth factor stimulus; neutrophil activation; angiogenesis; response to molecule of bacterial origin; G-protein coupled receptor signaling pathway; calcium-mediated signaling; regulation of cell adhesion; neutrophil chemotaxis; endoplasmic reticulum unfolded protein response; receptor internalization; intracellular signal transduction
CXCR4response to virus; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; inflammatory response; apoptotic process; dendritic cell chemotaxis; viral reproduction; initiation of viral infection; calcium-mediated signaling; entry into host cell; myelin maintenance; interspecies interaction between organisms; positive regulation of oligodendrocyte differentiation; regulation of chemotaxis; response to hypoxia; activation of MAPK activity
CXCR6viral genome replication; G-protein coupled receptor signaling pathway
CXorf21-
CXorf22-
CXorf23-
CXorf36-
CXorf57-
CXorf65-
CXXC1endoplasmic reticulum unfolded protein response; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; histone H3-K4 methylation; activation of signaling protein activity involved in unfolded protein response
CYB561A3-
CYB561D1transport; electron transport chain
CYB561D2electron transport chain; transport
CYB5D1-
CYB5R1sterol biosynthetic process
CYB5R4cell development; response to antibiotic; glucose homeostasis; insulin secretion; superoxide metabolic process; oxidation-reduction process; detection of oxygen; generation of precursor metabolites and energy
CYC1response to glucagon stimulus; transport; respiratory electron transport chain; small molecule metabolic process
CYFIP1ruffle organization; multicellular organismal development; axon extension; regulation of cell shape; lamellipodium assembly; cell differentiation; nervous system development
CYHR1-
CYLC1multicellular organismal development; spermatogenesis; cell differentiation
CYLC2spermatogenesis; multicellular organismal development; cell differentiation
CYLDregulation of microtubule cytoskeleton organization; positive regulation of extrinsic apoptotic signaling pathway; protein K63-linked deubiquitination; negative regulation of canonical Wnt receptor signaling pathway; translation; proteolysis; ubiquitin-dependent protein catabolic process; induction of apoptosis; cell cycle; Wnt receptor signaling pathway; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; negative regulation of NF-kappaB import into nucleus; innate immune response; nucleotide-binding oligomerization domain containing signaling pathway; regulation of mitotic cell cycle
CYP11A1maternal process involved in female pregnancy; granulosa cell differentiation; response to corticosterone stimulus; fractalkine metabolic process; cellular response to fibroblast growth factor stimulus; small molecule metabolic process; response to estrogen stimulus; response to alkaloid; response to hydrogen peroxide; response to drug; vitamin D metabolic process; response to genistein; response to fungicide; testosterone biosynthetic process; cellular response to lipopolysaccharide; cellular response to antibiotic; cellular response to cadmium ion; cellular response to cAMP; cellular response to interleukin-1; cellular response to tumor necrosis factor; cellular response to follicle-stimulating hormone stimulus; cellular response to peptide hormone stimulus; cellular response to transforming growth factor beta stimulus; phthalate metabolic process; Leydig cell differentiation; response to acid; organic acid metabolic process; C21-steroid hormone biosynthetic process; progesterone biosynthetic process; estro
CYP1A1coumarin metabolic process; response to hypoxia; porphyrin-containing compound metabolic process; xenobiotic metabolic process; cell proliferation; response to wounding; amine metabolic process; hepatocyte differentiation; maternal process involved in parturition; oxidation-reduction process; response to hyperoxia; hydrogen peroxide biosynthetic process; digestive tract development; response to arsenic-containing substance; response to antibiotic; positive regulation of S phase of mitotic cell cycle; small molecule metabolic process; cellular lipid metabolic process; camera-type eye development; 9-cis-retinoic acid biosynthetic process; response to drug; response to vitamin A; response to virus; response to nematode; response to herbicide; embryo development ending in birth or egg hatching; flavonoid metabolic process; response to iron(III) ion; response to organic cyclic compound; drug metabolic process; dibenzo-p-dioxin catabolic process; response to food; response to lipopolysaccharide; developmental proce
CYP1A2methylation; monocarboxylic acid metabolic process; drug catabolic process; exogenous drug catabolic process; small molecule metabolic process; cellular respiration; heterocycle metabolic process; hydrogen peroxide biosynthetic process; oxidation-reduction process; oxidative demethylation; oxidative deethylation; porphyrin-containing compound metabolic process; dibenzo-p-dioxin metabolic process; steroid catabolic process; cellular aromatic compound metabolic process; lung development; xenobiotic metabolic process; toxin biosynthetic process; post-embryonic development; alkaloid metabolic process; regulation of gene expression; monoterpenoid metabolic process; drug metabolic process
CYP1B1retina vasculature development in camera-type eye; oxidation-reduction process; small molecule metabolic process; endothelial cell migration; endothelial cell-cell adhesion; response to toxin; toxin metabolic process; estrogen metabolic process; visual perception; xenobiotic metabolic process; cellular aromatic compound metabolic process; angiogenesis; response to organic substance
CYP20A1-
CYP24A1osteoblast differentiation; vitamin metabolic process; xenobiotic metabolic process; steroid metabolic process; response to vitamin D; vitamin D metabolic process; vitamin D catabolic process; vitamin D receptor signaling pathway; oxidation-reduction process; small molecule metabolic process
CYP26A1vitamin metabolic process; xenobiotic metabolic process; metabolic process; retinoic acid catabolic process; small molecule metabolic process; negative regulation of retinoic acid receptor signaling pathway
CYP26C1retinoic acid catabolic process; oxidation-reduction process; central nervous system development; anterior/posterior pattern specification; neural crest cell development; xenobiotic metabolic process; small molecule metabolic process; organelle fusion; vitamin metabolic process; negative regulation of retinoic acid receptor signaling pathway
CYP27A1small molecule metabolic process; bile acid metabolic process; cholesterol metabolic process; bile acid biosynthetic process; xenobiotic metabolic process
CYP27B1response to interferon-gamma; negative regulation of cell growth; regulation of bone mineralization; response to lipopolysaccharide; response to vitamin D; negative regulation of calcidiol 1-monooxygenase activity; response to tumor necrosis factor; vitamin D metabolic process; vitamin D biosynthetic process; vitamin D catabolic process; response to estrogen stimulus; bone mineralization; small molecule metabolic process; positive regulation of keratinocyte differentiation; decidualization; calcium ion homeostasis; positive regulation of vitamin D 24-hydroxylase activity; xenobiotic metabolic process; calcium ion transport; steroid metabolic process; negative regulation of cell proliferation; vitamin metabolic process; positive regulation of vitamin D receptor signaling pathway; G1 to G0 transition
CYP2C18xenobiotic metabolic process; small molecule metabolic process
CYP2C9urea metabolic process; monocarboxylic acid metabolic process; drug catabolic process; exogenous drug catabolic process; cellular amide metabolic process; small molecule metabolic process; oxidation-reduction process; oxidative demethylation; drug metabolic process; monoterpenoid metabolic process; steroid metabolic process; xenobiotic metabolic process
CYP2J2linoleic acid metabolic process; icosanoid metabolic process; xenobiotic metabolic process; regulation of heart contraction; epoxygenase P450 pathway; small molecule metabolic process
CYP2R1vitamin metabolic process; small molecule metabolic process; vitamin D metabolic process; response to ionizing radiation; response to cesium ion; steroid metabolic process; xenobiotic metabolic process
CYP2U1small molecule metabolic process; xenobiotic metabolic process
CYP2W1small molecule metabolic process; xenobiotic metabolic process
CYP39A1small molecule metabolic process; bile acid metabolic process; digestion; xenobiotic metabolic process; cholesterol catabolic process; bile acid biosynthetic process; bile acid catabolic process
CYP3A5xenobiotic metabolic process; oxidative demethylation; small molecule metabolic process; drug catabolic process; alkaloid catabolic process; steroid metabolic process
CYP46A1nervous system development; small molecule metabolic process; bile acid metabolic process; xenobiotic metabolic process; cholesterol catabolic process; bile acid biosynthetic process
CYP4B1small molecule metabolic process; xenobiotic metabolic process
CYP4F11inflammatory response; xenobiotic metabolic process; small molecule metabolic process; oxidation-reduction process
CYP4F22-
CYP4V2response to stimulus; fatty acid omega-oxidation; visual perception
CYP7B1xenobiotic metabolic process; bile acid biosynthetic process; memory; circadian rhythm; cholesterol metabolic process; prostate gland epithelium morphogenesis; response to cAMP; positive regulation of epithelial cell proliferation; small molecule metabolic process; response to drug; negative regulation of intracellular estrogen receptor signaling pathway; bile acid metabolic process; cell death
CYP8B1bile acid metabolic process; small molecule metabolic process; xenobiotic metabolic process; bile acid biosynthetic process
CYR61positive regulation of BMP signaling pathway; positive regulation of cell migration; positive regulation of osteoblast proliferation; positive regulation of apoptotic process; negative regulation of apoptotic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; wound healing, spreading of cells; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; atrial septum morphogenesis; chondroblast differentiation; positive regulation of cartilage development; chorio-allantoic fusion; labyrinthine layer blood vessel development; extracellular matrix organization; positive regulation of cell-substrate adhesion; positive regulation of phospholipase activity; anatomical structure morphogenesis; cell proliferation; chemotaxis; ventricular septum development; apoptosis involved in heart morphogenesis; atrioventricular valve morphogenesis; intussusceptive angiogene
CYTH1vesicle-mediated transport; regulation of cell adhesion; regulation of ARF protein signal transduction
CYTH2actin cytoskeleton organization; endocytosis; regulation of ARF protein signal transduction; regulation of cell adhesion
CYTH4regulation of cell adhesion; regulation of ARF protein signal transduction
CYTIPregulation of cell adhesion
CYYR1-
D2HGDHresponse to manganese ion; response to zinc ion; response to cobalt ion; response to magnesium ion; cellular protein metabolic process; small molecule metabolic process; response to calcium ion; 2-oxoglutarate metabolic process
DAB1multicellular organismal development; nervous system development; cell differentiation
DAB2positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; negative regulation of canonical Wnt receptor signaling pathway; cell morphogenesis involved in differentiation; in utero embryonic development; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; excretion; pinocytosis; receptor-mediated endocytosis; positive regulation of protein phosphorylation; cell proliferation; negative regulation of cell growth; negative regulation of protein binding
DAB2IPnegative regulation of protein serine/threonine kinase activity; cellular response to epidermal growth factor stimulus; positive regulation of protein serine/threonine kinase activity; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of NF-kappaB transcription factor activity; negative regulation of epithelial to mesenchymal transition; negative regulation of epithelial cell migration; positive regulation of signal transduction; activation of JUN kinase activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of Ras protein signal transduction; positive regulation of Ras GTPase activity; negative regulation of Ras GTPase activity; negative regulation of catenin import into nucleus; negative regulation of epidermal growth factor receptor signaling pathway; positive regulation of apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of MAP kinase activity; positive regulation of JUN kinase a
DACH1negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell migration; negative regulation of transcription by competitive promoter binding; multicellular organismal development; regulation of transcription, DNA-dependent
DACH2regulation of transcription, DNA-dependent; multicellular organismal development; development of primary female sexual characteristics
DACT1Wnt receptor signaling pathway; multicellular organismal development
DAG1membrane protein ectodomain proteolysis; NLS-bearing substrate import into nucleus; cytoskeletal anchoring at plasma membrane; virus-host interaction; negative regulation of protein kinase B signaling cascade; negative regulation of cell migration; microtubule anchoring; negative regulation of MAPK cascade; interspecies interaction between organisms
DAGLAblood coagulation; cell death; lipid catabolic process; platelet activation
DAGLBblood coagulation; lipid catabolic process; platelet activation
DALRD3arginyl-tRNA aminoacylation
DAOsmall molecule metabolic process; D-alanine catabolic process; glyoxylate metabolic process; D-serine catabolic process; cellular nitrogen compound metabolic process; proline catabolic process
DAPK1intracellular protein kinase cascade; regulation of N-methyl-D-aspartate selective glutamate receptor activity; regulation of apoptotic process; regulation of autophagy; induction of apoptosis by extracellular signals; signal transduction; induction of apoptosis; anti-apoptosis; apoptotic process; protein phosphorylation; protein autophosphorylation
DAPK2protein phosphorylation; induction of apoptosis; intracellular protein kinase cascade; regulation of autophagy; regulation of apoptotic process; anoikis; protein autophosphorylation
DAPK3chromatin modification; neuron differentiation; regulation of apoptotic process; protein autophosphorylation; positive regulation of canonical Wnt receptor signaling pathway; regulation of cell motility; regulation of actin cytoskeleton reorganization; intracellular protein kinase cascade; regulation of mitosis; regulation of smooth muscle contraction; induction of apoptosis; protein phosphorylation; cytokinesis; regulation of transcription, DNA-dependent; regulation of autophagy
DARSprotein complex assembly; gene expression; aspartyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; translation
DARS2mitochondrial asparaginyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; gene expression; tRNA aminoacylation
DAW1-
DAZAP1spermatogenesis; cell differentiation; multicellular organismal development
DBHfear response; maternal behavior; regulation of apoptotic process; response to peptide hormone stimulus; small molecule metabolic process; positive regulation of vasoconstriction; octopamine metabolic process; response to copper ion; behavioral response to ethanol; response to pain; leukocyte migration; sensory perception of taste; bone development; cellular response to manganese ion; cellular response to nicotine; homoiothermy; catecholamine biosynthetic process; synaptic transmission; blood vessel remodeling; response to amphetamine; leukocyte mediated immunity; glucose homeostasis; memory; locomotory behavior; visual learning; response to iron ion; response to ozone; response to organic cyclic compound; response to estradiol stimulus; cellular nitrogen compound metabolic process; social behavior; norepinephrine biosynthetic process; dopamine catabolic process; cytokine production; regulation of cell proliferation; multicellular organismal aging
DBN1regulation of neuronal synaptic plasticity; regulation of dendrite development; cell differentiation; nervous system development; multicellular organismal development; actin filament organization
DBNLcellular component disassembly involved in apoptosis; activation of JUN kinase activity; Rac protein signal transduction; apoptotic process; endocytosis
DBR1nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions
DBX2-
DCAF11protein ubiquitination
DCAF12L2-
DCAF15-
DCAF16protein ubiquitination
DCAF4L2-
DCAF5protein ubiquitination
DCAF8protein ubiquitination
DCAKDcoenzyme A biosynthetic process
DCCapoptotic process; negative regulation of dendrite development; positive regulation of ERK1 and ERK2 cascade; negative regulation of collateral sprouting; negative regulation of neuron projection development; positive regulation of neuron projection development; axon guidance; response to amphetamine; axonogenesis; multicellular organismal development; induction of apoptosis; regulation of apoptotic process
DCDC1intracellular signal transduction
DCDC2intracellular signal transduction; nervous system development; cellular defense response; neuron migration
DCHS2cell adhesion; homophilic cell adhesion
DCLK1response to virus; intracellular signal transduction; cell differentiation; endosome transport; central nervous system development; nervous system development; multicellular organismal development; protein phosphorylation
DCLK2intracellular signal transduction
DCLK3-
DCLRE1ADNA repair; cell cycle; mitosis; cell division
DCLRE1Btelomeric 3' overhang formation; protection from non-homologous end joining at telomere; telomeric loop formation; DNA repair; cell cycle checkpoint; telomere maintenance
DCNwound healing; response to lipopolysaccharide; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; organ morphogenesis; aging; skeletal muscle tissue development; placenta development; kidney development; response to mechanical stimulus
DCPSdeadenylation-dependent decapping of nuclear-transcribed mRNA; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; gene expression; RNA metabolic process; mRNA metabolic process; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
DCST1-
DCST2-
DCSTAMPosteoclast differentiation
DCTpositive regulation of neuroblast proliferation; melanin biosynthetic process from tyrosine; epidermis development; ventricular zone neuroblast division; developmental pigmentation; cell development
DCTN1mitotic cell cycle; endoplasmic reticulum unfolded protein response; cell death; nervous system development; mitosis; activation of signaling protein activity involved in unfolded protein response; transport; G2/M transition of mitotic cell cycle
DCTN4-
DCUN1D2-
DCXaxon guidance; response to electrical stimulus; dendrite morphogenesis; axon extension; intracellular signal transduction; cell differentiation; central nervous system projection neuron axonogenesis; brain development; neuron migration; multicellular organismal development; nervous system development; central nervous system development
DCXRD-xylose metabolic process; glucose metabolic process; NADP metabolic process; carbohydrate metabolic process; protein homotetramerization; xylulose metabolic process; oxidation-reduction process
DDB1cell cycle checkpoint; nucleotide-excision repair, DNA damage removal; DNA repair; nucleotide-excision repair; Wnt receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; interspecies interaction between organisms
DDHD1lipid catabolic process
DDHD2lipid catabolic process
DDI1proteolysis
DDIAScell cycle; apoptotic process; cell cycle arrest
DDIT4Lnegative regulation of signal transduction
DDOaspartate metabolic process; aspartate catabolic process; insemination; grooming behavior; hormone metabolic process
DDOSTresponse to cytokine stimulus; innate immune response; cellular protein metabolic process; post-translational protein modification; translation; protein N-linked glycosylation; T cell activation; protein N-linked glycosylation via asparagine; gene expression; SRP-dependent cotranslational protein targeting to membrane; protein glycosylation
DDR2chondrocyte proliferation; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; protein autophosphorylation; positive regulation of fibroblast proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of extracellular matrix disassembly; collagen-activated tyrosine kinase receptor signaling pathway; ossification; endochondral bone growth; cell adhesion; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of bone mineralization; peptidyl-tyrosine phosphorylation; positive regulation of fibroblast migration; regulation of extracellular matrix disassembly
DDX1spliceosome assembly; double-strand break repair; regulation of transcription, DNA-dependent; mRNA processing; regulation of translational initiation; multicellular organismal development; DNA duplex unwinding; nucleic acid phosphodiester bond hydrolysis
DDX17regulation of skeletal muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of intracellular estrogen receptor signaling pathway; RNA processing
DDX18-
DDX20spliceosomal snRNP assembly; negative regulation of transcription from RNA polymerase II promoter; assembly of spliceosomal tri-snRNP; RNA processing; mRNA processing; induction of apoptosis; RNA splicing; RNA metabolic process; ncRNA metabolic process; positive regulation of apoptotic process; gene expression
DDX24RNA metabolic process
DDX26B-
DDX28-
DDX39AmRNA export from nucleus; nuclear mRNA splicing, via spliceosome; RNA splicing
DDX3Xinterspecies interaction between organisms
DDX3Y-
DDX4multicellular organismal development; sperm motility
DDX41nuclear mRNA splicing, via spliceosome; RNA processing; apoptotic process; multicellular organismal development; RNA splicing
DDX42regulation of anti-apoptosis; protein localization
DDX43-
DDX46mRNA processing; RNA splicing
DDX47RNA splicing; apoptotic process; mRNA processing; rRNA processing
DDX49-
DDX51rRNA processing
DDX53-
DDX55-
DDX56rRNA processing
DDX58positive regulation of defense response to virus by host; detection of virus; negative regulation of type I interferon production; positive regulation of interferon-alpha production; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of interferon-beta production; positive regulation of transcription factor import into nucleus; innate immune response; positive regulation of transcription from RNA polymerase II promoter
DDX59-
DDX60response to virus
DEAF1regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; germ cell development; multicellular organismal development; neural tube closure; embryonic skeletal system development; regulation of mammary gland epithelial cell proliferation; anatomical structure morphogenesis; nervous system development
DECR1fatty acid beta-oxidation; cellular lipid metabolic process; small molecule metabolic process; protein homotetramerization
DEDDregulation of apoptotic process; negative regulation of transcription, DNA-dependent; induction of apoptosis via death domain receptors; spermatogenesis; induction of apoptosis
DEF6-
DEFA4defense response to fungus; innate immune response; defense response to bacterium; killing of cells of other organism
DEFB112defense response to bacterium
DEFB115defense response to bacterium
DEFB116defense response to bacterium
DEFB125defense response to bacterium
DEFB126defense response to bacterium
DEFB128defense response to bacterium
DEFB129defense response to bacterium
DEGS1small molecule metabolic process; sphingolipid biosynthetic process; sphingolipid metabolic process; unsaturated fatty acid biosynthetic process
DEKviral genome replication; chromatin modification; signal transduction; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
DENND1Asynaptic vesicle endocytosis
DENND1B-
DENND2A-
DENND2C-
DENND2D-
DENND3-
DENND4C-
DENND5A-
DENND6A-
DEPDC1Bsmall GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction
DEPDC4intracellular signal transduction
DEPDC5intracellular signal transduction
DEPDC7regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
DEPTORnegative regulation of TOR signaling cascade; negative regulation of protein kinase activity; regulation of apoptotic process; negative regulation of cell size; intracellular signal transduction
DERL3ER-associated protein catabolic process; endoplasmic reticulum unfolded protein response
DESregulation of heart contraction; muscle filament sliding; cytoskeleton organization; muscle contraction
DESI2-
DFNB31inner ear receptor stereocilium organization; sensory perception of light stimulus; sensory perception of sound; retina homeostasis
DFNB59sensory perception of sound
DGAT1glycerolipid metabolic process; diacylglycerol metabolic process; small molecule metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA metabolic process; very-low-density lipoprotein particle assembly; insulin secretion; lipid storage; triglyceride biosynthetic process; triglyceride metabolic process
DGAT2cholesterol homeostasis; cellular triglyceride homeostasis; cellular lipid metabolic process; small molecule metabolic process; diacylglycerol metabolic process; fat pad development; low-density lipoprotein particle clearance; lipid storage; triglyceride biosynthetic process; lipid biosynthetic process; cellular response to oleic acid; long-chain fatty-acyl-CoA metabolic process; glycerol metabolic process; fatty acid homeostasis; regulation of plasma lipoprotein particle levels
DGCR2cell adhesion; organ morphogenesis
DGCR8primary miRNA processing
DGKAactivation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; intracellular signal transduction; platelet activation; blood coagulation
DGKDprotein homooligomerization; diacylglycerol metabolic process; endocytosis; signal transduction; epidermal growth factor receptor signaling pathway; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; multicellular organismal development; blood coagulation; protein transport; cell growth; second-messenger-mediated signaling; platelet activation; response to organic substance
DGKEphospholipid biosynthetic process; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation; platelet activation; intracellular signal transduction
DGKGsignal transduction; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; blood coagulation; platelet activation; intracellular signal transduction; neuron development
DGKHactivation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; platelet activation; intracellular signal transduction; protein oligomerization; blood coagulation
DGKIplatelet activation; blood coagulation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; regulation of Rap GTPase activity; intracellular signal transduction; positive regulation of Ras protein signal transduction; negative regulation of catalytic activity
DGKQprotein kinase C signaling cascade; thrombin receptor signaling pathway; intracellular signal transduction; response to ATP; platelet activation; cAMP-mediated signaling; blood coagulation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; G-protein coupled receptor signaling pathway
DGKZblood coagulation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; lipid phosphorylation; negative regulation of Ras protein signal transduction; negative regulation of mitotic cell cycle; intracellular signal transduction; mitotic cell cycle G1/S transition DNA damage checkpoint; platelet activation; cell migration
DHCR7blood vessel development; cholesterol biosynthetic process; post-embryonic development; cell differentiation; lung development; multicellular organism growth; regulation of cell proliferation; small molecule metabolic process; regulation of cholesterol biosynthetic process
DHDHcarbohydrate metabolic process; D-xylose catabolic process
DHODHregulation of mitochondrial fission; nucleobase-containing small molecule metabolic process; pyrimidine nucleoside biosynthetic process; small molecule metabolic process; positive regulation of apoptotic process; pyrimidine nucleotide biosynthetic process; 'de novo' pyrimidine base biosynthetic process; pyrimidine base metabolic process; UMP biosynthetic process
DHRS1-
DHRS13-
DHRS2oxidation-reduction process; response to toxin; negative regulation of cell proliferation; C21-steroid hormone metabolic process; cellular response to oxidative stress; myeloid dendritic cell differentiation; negative regulation of apoptotic process
DHRS3visual perception; retinol metabolic process
DHRS7-
DHRS7B-
DHTKD1tricarboxylic acid cycle; glycolysis
DHX15RNA splicing; mRNA processing
DHX30-
DHX32-
DHX33positive regulation of transcription from RNA polymerase I promoter
DHX36-
DHX37-
DHX38nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; termination of RNA polymerase II transcription; mRNA export from nucleus; RNA splicing; gene expression; mRNA 3'-end processing
DHX40-
DHX57-
DHX58innate immune response
DHX8nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing
DHX9nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; cellular response to heat; CRD-mediated mRNA stabilization
DIAPH1cellular component organization; cellular response to histamine; cytoskeleton organization; sensory perception of sound; regulation of cell shape; actin cytoskeleton organization; actin filament polymerization; regulation of release of sequestered calcium ion into cytosol; protein localization to microtubule; regulation of microtubule-based process; neuron projection development
DIAPH2cytokinesis; oogenesis; cell differentiation; actin filament polymerization; actin cytoskeleton organization; cellular component organization; female gamete generation; multicellular organismal development
DIAPH3actin cytoskeleton organization; cellular component organization
DICER1olfactory bulb interneuron differentiation; gene silencing by RNA; post-embryonic development; hair follicle cell proliferation; targeting of mRNA for destruction involved in RNA interference; production of siRNA involved in RNA interference; lung development; cerebral cortex development; RNA processing; nerve development; stem cell maintenance; positive regulation of Schwann cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of gene expression; angiogenesis; negative regulation of Schwann cell proliferation; zygote asymmetric cell division; regulation of cell differentiation; hair follicle morphogenesis; positive regulation of myelination; peripheral nervous system myelin formation; embryonic hindlimb morphogenesis; production of miRNAs involved in gene silencing by miRNA; multicellular organism growth; regulation of enamel mineralization; intestinal epithelial cell development; regulation of odontogenesis of dentin-containing tooth; negative regul
DIDO1transcription, DNA-dependent; apoptotic process
DIO1thyroid hormone generation; cellular nitrogen compound metabolic process; hormone biosynthetic process; small molecule metabolic process
DIP2B-
DIP2C-
DIRAS1small GTPase mediated signal transduction; signal transduction
DIRAS3small GTPase mediated signal transduction; signal transduction; regulation of gene expression by genetic imprinting; regulation of cyclin-dependent protein kinase activity; GTP catabolic process
DIS3nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; CUT catabolic process; rRNA catabolic process; rRNA processing; gene expression; mRNA metabolic process; RNA metabolic process
DIS3LrRNA catabolic process
DIS3L2-
DISC1nervous system development; multicellular organismal development; microtubule cytoskeleton organization; neuron migration; positive regulation of neuroblast proliferation; positive regulation of Wnt receptor signaling pathway
DISP1diaphragm development; determination of left/right symmetry; protein homotrimerization; regulation of protein secretion; smoothened signaling pathway; embryonic pattern specification; dorsal/ventral pattern formation; peptide transport; patched ligand maturation
DISP2smoothened signaling pathway
DKK2positive regulation of canonical Wnt receptor signaling pathway; multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway
DKK3negative regulation of canonical Wnt receptor signaling pathway; negative regulation of transcription, DNA-dependent; negative regulation of cortisol biosynthetic process; multicellular organismal development; negative regulation of aldosterone biosynthetic process; adrenal gland development; anatomical structure morphogenesis
DKKL1positive regulation of fat cell differentiation; anatomical structure morphogenesis; signal transduction
DLC1positive regulation of Rho GTPase activity; signal transduction; activation of cysteine-type endopeptidase activity involved in apoptotic process; forebrain development; negative regulation of cell migration; activation of phospholipase C activity; small GTPase mediated signal transduction; negative regulation of cell proliferation; regulation of cell shape; hindbrain morphogenesis; actin cytoskeleton organization; induction of apoptosis; cellular response to insulin stimulus; regulation of actin cytoskeleton organization; heart morphogenesis; neural tube closure; negative regulation of Rho protein signal transduction; positive regulation of protein dephosphorylation; focal adhesion assembly; regulation of small GTPase mediated signal transduction; negative regulation of stress fiber assembly
DLDcellular nitrogen compound metabolic process; pyruvate metabolic process; tricarboxylic acid cycle; 2-oxoglutarate metabolic process; mitochondrial electron transport, NADH to ubiquinone; proteolysis; lysine catabolic process; gastrulation; aging; branched chain family amino acid catabolic process; lipoate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; regulation of membrane potential; small molecule metabolic process; cell redox homeostasis; sperm capacitation; dihydrolipoamide metabolic process
DLEC1negative regulation of cell proliferation
DLG1mitotic cell cycle G1/S transition checkpoint; interspecies interaction between organisms; negative regulation of mitotic cell cycle; tight junction assembly; protein localization in plasma membrane; cell-cell adhesion; axon guidance; synaptic transmission; establishment or maintenance of cell polarity; endothelial cell proliferation; actin filament organization; cortical actin cytoskeleton organization
DLG2synaptic transmission; negative regulation of phosphatase activity; sensory perception of pain; receptor clustering; neuronal ion channel clustering
DLG3negative regulation of cell proliferation; negative regulation of phosphatase activity; axon guidance; synaptic transmission
DLG5regulation of apoptotic process; intracellular signal transduction; cell-cell adhesion; negative regulation of cell proliferation; signal transduction
DLGAP1synaptic transmission
DLGAP3cell-cell signaling
DLGAP4cell-cell signaling
DLGAP5cell cycle; M phase of mitotic cell cycle; cell-cell signaling; cell proliferation; positive regulation of mitotic metaphase/anaphase transition; mitotic chromosome movement towards spindle pole
DLK1multicellular organismal development; embryo development; post-embryonic development; embryonic skeletal system development
DLK2regulation of fat cell differentiation
DLL1cell fate determination; somite specification; Notch signaling pathway; Notch receptor processing; cell-cell signaling; multicellular organismal development; compartment pattern specification; neuronal stem cell maintenance; loop of Henle development; proximal tubule development; regulation of neurogenesis; inner ear development; negative regulation of neuron differentiation; negative regulation of myeloid cell differentiation; negative regulation of auditory receptor cell differentiation; regulation of cell adhesion; cell differentiation; determination of left/right symmetry; hemopoiesis
DLL3tissue development; cell differentiation; negative regulation of neurogenesis; positive regulation of neurogenesis; negative regulation of astrocyte differentiation; paraxial mesoderm development; negative regulation of Notch signaling pathway; skeletal system development; somitogenesis; multicellular organismal development; compartment pattern specification; central nervous system development
DLSTsmall molecule metabolic process; cellular nitrogen compound metabolic process; metabolic process; NADH metabolic process; lysine catabolic process; 2-oxoglutarate metabolic process; tricarboxylic acid cycle; generation of precursor metabolites and energy
DLX1negative regulation of neuron apoptosis; negative regulation of oligodendrocyte differentiation; embryonic skeletal system development; odontogenesis of dentin-containing tooth; cell differentiation; cerebral cortex GABAergic interneuron fate commitment; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; forebrain neuron differentiation; hippocampus development; negative regulation of transcription from RNA polymerase II promoter; multicellular organismal development; proximal/distal pattern formation
DLX3placenta development; regulation of transcription, DNA-dependent; multicellular organismal development; blood vessel development
DLX5axon guidance; anatomical structure formation involved in morphogenesis; skeletal system development; embryonic limb morphogenesis; positive regulation of epithelial cell proliferation; palate development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of osteoblast differentiation; ear development; inner ear morphogenesis; specification of segmental identity, mandibular segment; epithelial cell differentiation; osteoblast differentiation; olfactory pit development; head development; face morphogenesis; bone morphogenesis; positive regulation of canonical Wnt receptor signaling pathway; cell proliferation; nervous system development; multicellular organismal development; endochondral ossification
DMAP1histone H4 acetylation; positive regulation of transcription factor import into nucleus; regulation of growth; chromatin modification; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; histone H2A acetylation; negative regulation of transcription, DNA-dependent
DMC1oocyte maturation; male meiosis I; spermatogenesis; spermatid development; pachytene; female gamete generation; reciprocal meiotic recombination; meiosis; cell cycle; DNA metabolic process; ovarian follicle development
DMDolfactory nerve structural organization; neuron projection morphogenesis; muscle cell homeostasis; neurotransmitter receptor metabolic process; peptide biosynthetic process; regulation of transcription, DNA-dependent; muscle organ development; skeletal muscle tissue development; muscle filament sliding
DMGDHcholine metabolic process; glycine metabolic process; glycine catabolic process
DMKN-
DMPKregulation of sodium ion transport; protein phosphorylation; cellular calcium ion homeostasis; nuclear envelope organization; regulation of heart contraction; muscle cell apoptosis; regulation of myotube differentiation; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
DMRT1sex determination; regulation of transcription, DNA-dependent; multicellular organismal development; sex differentiation; male gonad development; intracellular signal transduction; cell differentiation
DMRT3multicellular organismal development; sex differentiation; cell differentiation; regulation of transcription, DNA-dependent
DMRTA1regulation of transcription, DNA-dependent; sex differentiation; cell differentiation
DMTF1regulation of transcription, DNA-dependent; cell cycle
DMWDmeiosis
DMXL1-
DMXL2-
DNAAF1axonemal dynein complex assembly; cilium morphogenesis
DNAH14microtubule-based movement
DNAH2ciliary or flagellar motility; microtubule-based movement
DNAH3microtubule-based movement; ciliary or flagellar motility
DNAH5ciliary or flagellar motility; microtubule-based movement; metabolic process
DNAH6microtubule-based movement
DNAH7microtubule-based movement; ciliary or flagellar motility
DNAH8ciliary or flagellar motility; microtubule-based movement
DNAH9cell projection organization; spermatogenesis; microtubule-based movement; cellular component movement
DNAI2cell projection organization; cilium assembly
DNAJA3negative regulation of interferon-gamma-mediated signaling pathway; skeletal muscle acetylcholine-gated channel clustering; neuromuscular junction development; small GTPase mediated signal transduction; mitochondrion organization; activation-induced cell death of T cells; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; negative regulation of protein kinase activity; protein folding; mitochondrial DNA replication; negative regulation of transcription from RNA polymerase II promoter; cell aging; regulation of catalytic activity; cell death; negative regulation of cell proliferation; response to heat; embryo development; positive regulation of protein ubiquitination; negative regulation of NF-kappaB transcription factor activity; T cell differentiation in thymus; response to interferon-gamma; positive regulation of T cell proliferation; positive regulation of apoptotic process; negative regulation of apoptotic process; negative regulation of I-kappaB kinase/NF
DNAJA4response to heat; protein folding
DNAJB11activation of signaling protein activity involved in unfolded protein response; protein folding; mRNA modification; endoplasmic reticulum unfolded protein response
DNAJB12protein folding
DNAJB2negative regulation of cell growth; negative regulation of protein deubiquitination; protein folding; response to unfolded protein; negative regulation of cell proliferation; ER-associated protein catabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of inclusion body assembly; positive regulation of protein ubiquitination
DNAJB4response to heat; protein folding; response to unfolded protein
DNAJB5response to unfolded protein; negative regulation of transcription from RNA polymerase II promoter; protein folding
DNAJB8protein folding
DNAJB9endoplasmic reticulum unfolded protein response; ER-associated protein catabolic process; activation of signaling protein activity involved in unfolded protein response; protein folding
DNAJC11protein folding
DNAJC12protein folding
DNAJC13-
DNAJC16cell redox homeostasis; protein folding
DNAJC17protein folding
DNAJC2G2 phase of mitotic cell cycle; DNA replication; chromatin modification; negative regulation of cell growth; positive regulation of transcription, DNA-dependent; 'de novo' cotranslational protein folding
DNAJC21protein folding
DNAJC25protein folding
DNAJC28-
DNAJC6post-Golgi vesicle-mediated transport; cellular membrane organization
DNALI1cellular component movement; single fertilization
DNASE1DNA catabolic process; apoptotic process
DNASE1L2DNA metabolic process; DNA catabolic process
DNHD1microtubule-based movement
DNM1GTP catabolic process; receptor-mediated endocytosis; endosome organization; endocytosis
DNM1Lperoxisome fission; dynamin polymerization involved in mitochondrial fission; apoptotic process; cellular component disassembly involved in apoptosis; mitochondrial fragmentation involved in apoptosis; positive regulation of protein secretion; positive regulation of mitochondrial fission; membrane fission involved in mitochondrial fission; positive regulation of intrinsic apoptotic signaling pathway
DNM2synaptic vesicle transport; G2/M transition of mitotic cell cycle; GTP catabolic process; regulation of transcription, DNA-dependent; post-Golgi vesicle-mediated transport; endocytosis; signal transduction; cellular membrane organization; receptor internalization; transferrin transport; positive regulation of apoptotic process; positive regulation of transcription, DNA-dependent
DNMBPintracellular signal transduction; regulation of Rho protein signal transduction
DNMT1C-5 methylation of cytosine; cellular response to amino acid stimulus; negative regulation of histone H3-K9 methylation; positive regulation of histone H3-K4 methylation; regulation of cell proliferation; chromatin modification; gene silencing; positive regulation of gene expression; maintenance of DNA methylation; DNA methylation; negative regulation of transcription from RNA polymerase II promoter
DNMT3ADNA methylation; negative regulation of transcription from RNA polymerase II promoter; S-adenosylhomocysteine metabolic process; S-adenosylmethioninamine metabolic process; cellular response to amino acid stimulus; hypermethylation of CpG island; DNA methylation involved in gamete generation; DNA methylation involved in embryo development; chromatin modification; DNA methylation on cytosine within a CG sequence; spermatogenesis; regulation of gene expression by genetic imprinting; methylation-dependent chromatin silencing; C-5 methylation of cytosine
DNMT3Bnegative regulation of histone H3-K9 methylation; C-5 methylation of cytosine; cellular response to amino acid stimulus; response to drug; negative regulation of transcription from RNA polymerase II promoter; DNA methylation; methylation-dependent chromatin silencing; regulation of gene expression by genetic imprinting; response to ionizing radiation; DNA methylation on cytosine within a CG sequence; positive regulation of gene expression; protein complex localization; positive regulation of histone H3-K4 methylation; DNA methylation involved in embryo development; positive regulation of neuron differentiation; negative regulation of gene expression, epigenetic; S-adenosylhomocysteine metabolic process; S-adenosylmethioninamine metabolic process
DNPEPproteolysis; peptide metabolic process
DNTTDNA modification
DNTTIP1-
DOCK11regulation of catalytic activity; blood coagulation
DOCK2membrane raft polarization; establishment of T cell polarity; immunological synapse formation; chemotaxis; viral reproduction; actin cytoskeleton organization; positive thymic T cell selection; negative thymic T cell selection; alpha-beta T cell proliferation; regulation of defense response to virus by virus
DOCK7microtubule cytoskeleton organization; positive regulation of peptidyl-serine phosphorylation; multicellular organismal development; nervous system development; axonogenesis; establishment of neuroblast polarity; cell differentiation; neuron projection development; activation of Rac GTPase activity
DOCK8blood coagulation
DOK2leukocyte migration; blood coagulation; Ras protein signal transduction; signal transduction; cell surface receptor signaling pathway
DOK3Ras protein signal transduction
DOK5nervous system development; MAPK cascade; transmembrane receptor protein tyrosine kinase signaling pathway
DOK6-
DOK7positive regulation of protein tyrosine kinase activity
DOLKcellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; post-translational protein modification; dolichyl monophosphate biosynthetic process; protein N-linked glycosylation via asparagine; dolichyl diphosphate biosynthetic process
DOPEY1Golgi to endosome transport; endoplasmic reticulum organization; protein transport
DOPEY2Golgi to endosome transport; endoplasmic reticulum organization; multicellular organismal development; protein transport
DOT1Lchromatin modification; histone lysine methylation; regulation of JAK-STAT cascade; regulation of transcription regulatory region DNA binding
DPAGT1protein N-linked glycosylation; protein oligomerization; cellular protein metabolic process; post-translational protein modification; dolichol biosynthetic process; protein N-linked glycosylation via asparagine; metabolic process; dolichol-linked oligosaccharide biosynthetic process; UDP-N-acetylglucosamine metabolic process
DPCD-
DPEP1negative regulation of cell migration; cellular response to drug; negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; proteolysis; glutathione metabolic process; antibiotic metabolic process; cellular response to calcium ion; homocysteine metabolic process; cellular lactam catabolic process; cellular response to nitric oxide
DPEP2small molecule metabolic process; leukotriene biosynthetic process; prostanoid metabolic process; proteolysis
DPF2regulation of transcription, DNA-dependent; induction of apoptosis by extracellular signals; induction of apoptosis; apoptotic process
DPH1translation; cell proliferation; peptidyl-diphthamide biosynthetic process from peptidyl-histidine
DPH6-
DPM1protein N-linked glycosylation via asparagine; dolichol-linked oligosaccharide biosynthetic process; C-terminal protein lipidation; GPI anchor biosynthetic process; dolichol metabolic process; GDP-mannose metabolic process; protein mannosylation; protein O-linked mannosylation; post-translational protein modification; cellular protein metabolic process
DPP10proteolysis
DPP4cell adhesion; establishment of localization; endothelial cell migration; T cell activation; regulation of cell-cell adhesion mediated by integrin; T cell costimulation; negative regulation of extracellular matrix disassembly; positive regulation of cell proliferation; proteolysis; regulation of T cell mediated immunity; response to hypoxia
DPP7proteolysis
DPP8immune response; proteolysis
DPPA3embryonic cleavage
DPPA5multicellular organismal development
DPY19L4-
DPYDthymidine catabolic process; nucleobase-containing small molecule metabolic process; pyrimidine nucleoside catabolic process; small molecule metabolic process; UMP biosynthetic process; uracil catabolic process; thymine catabolic process; pyrimidine base catabolic process; pyrimidine base metabolic process; purine base catabolic process
DPYSnucleobase-containing small molecule metabolic process; protein homotetramerization; pyrimidine nucleoside catabolic process; small molecule metabolic process; uracil catabolic process; thymine catabolic process; pyrimidine base catabolic process; pyrimidine base metabolic process; beta-alanine metabolic process
DPYSL2positive regulation of glutamate secretion; synaptic vesicle transport; regulation of neuron differentiation; response to drug; response to cocaine; cell differentiation; olfactory bulb development; spinal cord development; brain development; axon guidance; nervous system development; multicellular organismal development; signal transduction; cytoskeleton organization; pyrimidine base catabolic process; nucleobase-containing compound metabolic process; response to amphetamine
DPYSL3axon guidance; cellular response to cytokine stimulus; actin crosslink formation; positive regulation of filopodium assembly; protein homooligomerization; actin filament bundle assembly; negative regulation of cell migration; negative regulation of neuron projection development; positive regulation of neuron projection development; pyrimidine base catabolic process; response to axon injury
DPYSL4pyrimidine base catabolic process; nervous system development; axon guidance
DQX1-
DRAM1autophagy; apoptotic process
DRAXIN-
DRC1-
DRC7spermatogenesis; ciliary or flagellar motility; cell differentiation
DRD1synaptic transmission, dopaminergic; behavioral fear response; conditioned taste aversion; temperature homeostasis; response to amphetamine; negative regulation of protein kinase activity; protein import into nucleus; intracellular protein transport; muscle contraction; G-protein signaling, coupled to cyclic nucleotide second messenger; activation of adenylate cyclase activity by G-protein signaling pathway; behavioral response to cocaine; operant conditioning; regulation of dopamine metabolic process; negative regulation of circadian sleep/wake cycle, sleep; dopamine metabolic process; response to drug; eating behavior; positive regulation of potassium ion transport; regulation of ion transport; glucose import; sensitization; activation of adenylate cyclase activity by dopamine receptor signaling pathway; regulation of long-term neuronal synaptic plasticity; positive regulation of release of sequestered calcium ion into cytosol; elevation of cytosolic calcium ion concentration involved in G-protein signaling
DRD2cerebral cortex GABAergic interneuron migration; Wnt receptor signaling pathway; regulation of dopamine secretion; response to iron ion; response to toxin; response to light stimulus; visual learning; associative learning; negative regulation of cell proliferation; protein localization; feeding behavior; adenohypophysis development; negative regulation of cell migration; peristalsis; regulation of cAMP metabolic process; forebrain development; auditory behavior; activation of protein kinase activity; regulation of synaptic transmission, GABAergic; circadian regulation of gene expression; response to histamine; response to nicotine; positive regulation of urine volume; G-protein signaling, coupled to cAMP nucleotide second messenger; temperature homeostasis; response to hypoxia; synaptic transmission, dopaminergic; response to amphetamine; neurological system process involved in regulation of systemic arterial blood pressure; regulation of heart rate; regulation of sodium ion transport; G-protein coupled recep
DRD3learning; positive regulation of transcription from RNA polymerase II promoter; positive regulation of mitosis; negative regulation of blood pressure; response to ethanol; regulation of circadian sleep/wake cycle, sleep; response to morphine; response to drug; dopamine metabolic process; response to cocaine; regulation of multicellular organism growth; acid secretion; behavioral response to cocaine; negative regulation of oligodendrocyte differentiation; arachidonic acid secretion; negative regulation of protein secretion; musculoskeletal movement, spinal reflex action; regulation of dopamine uptake; negative regulation of protein kinase B signaling cascade; prepulse inhibition; negative regulation of dopamine receptor signaling pathway; positive regulation of dopamine receptor signaling pathway; social behavior; negative regulation of transcription from RNA polymerase II promoter; synaptic transmission, dopaminergic; response to amphetamine; regulation of blood volume by renin-angiotensin; G-protein coupled
DRD4response to histamine; positive regulation of kinase activity; positive regulation of sodium:hydrogen antiporter activity; negative regulation of cAMP biosynthetic process; olfactory learning; adult locomotory behavior; short-term memory; dopamine receptor signaling pathway; inhibition of adenylate cyclase activity by dopamine receptor signaling pathway; negative regulation of adenylate cyclase activity; cellular calcium ion homeostasis; response to amphetamine; synaptic transmission, dopaminergic; behavioral fear response; activation of MAPK activity; regulation of dopamine metabolic process; social behavior; regulation of inhibitory postsynaptic membrane potential; negative regulation of calcium ion transport via voltage-gated calcium channel activity; positive regulation of dopamine uptake; regulation of calcium-mediated signaling; negative regulation of protein secretion; behavioral response to ethanol; behavioral response to cocaine; regulation of neurotransmitter secretion; fear response; dopamine metab
DRG2signal transduction
DRP2central nervous system development
DSC1cell adhesion; homophilic cell adhesion
DSC2cell adhesion; homophilic cell adhesion
DSC3cell adhesion; homophilic cell adhesion; protein stabilization
DSCAMdendrite self-avoidance; post-embryonic retina morphogenesis in camera-type eye; nervous system development; positive regulation of axon extension involved in axon guidance; dendrite morphogenesis; locomotory behavior; negative regulation of cell adhesion; cell adhesion; positive regulation of phosphorylation
DSCAML1dorsal/ventral pattern formation; embryonic skeletal system morphogenesis; dendrite self-avoidance; brain development; central nervous system development; axonogenesis; negative regulation of cell adhesion; cell fate determination; homophilic cell adhesion
DSCC1cell cycle; post-translational protein acetylation; maintenance of mitotic sister chromatid cohesion; regulation of DNA replication
DSEL-
DSG1apoptotic process; cellular component disassembly involved in apoptosis; cell-cell junction assembly; homophilic cell adhesion; cell-cell adhesion; calcium-dependent cell-cell adhesion; protein stabilization
DSG2cellular component disassembly involved in apoptosis; execution phase of apoptosis; homophilic cell adhesion; cell adhesion; apoptotic process
DSG3apoptotic process; cellular component disassembly involved in apoptosis; cell adhesion; homophilic cell adhesion
DSG4homophilic cell adhesion; cell adhesion
DSPepidermis development; skin development; wound healing; adherens junction organization; keratinocyte differentiation; cell-cell adhesion; cellular component disassembly involved in apoptosis; apoptotic process; peptide cross-linking
DSPPskeletal system development; ossification; multicellular organismal development; biomineral tissue development; cellular response to cell-matrix adhesion
DSTintermediate filament cytoskeleton organization; cell motility; intracellular transport; hemidesmosome assembly; cytoplasmic microtubule organization; regulation of microtubule polymerization or depolymerization; maintenance of cell polarity; cytoskeleton organization; cell cycle arrest; cell adhesion; integrin-mediated signaling pathway; axonogenesis; retrograde axon cargo transport; response to wounding; microtubule cytoskeleton organization
DSTYK-
DTNAneuromuscular synaptic transmission; synaptic transmission; signal transduction; striated muscle contraction
DTNBP1neuron projection morphogenesis; neuron projection development; cellular membrane organization; blood coagulation; organelle organization; post-Golgi vesicle-mediated transport; actin cytoskeleton reorganization; response to stimulus; platelet dense granule organization; regulation of dopamine receptor signaling pathway
DTX1transcription, DNA-dependent; transcription from RNA polymerase II promoter; cell surface receptor signaling pathway; regulation of Notch signaling pathway; glial cell differentiation; negative regulation of T cell differentiation; negative regulation of neuron differentiation
DTX3Lresponse to DNA damage stimulus; histone monoubiquitination; chromatin modification
DUOX1oxidation-reduction process; response to oxidative stress; cytokine-mediated signaling pathway; cuticle development; hormone biosynthetic process; superoxide anion generation; hydrogen peroxide catabolic process; hydrogen peroxide biosynthetic process; response to cAMP
DUOX2oxidation-reduction process; response to cAMP; adenohypophysis morphogenesis; inner ear development; hydrogen peroxide catabolic process; hormone biosynthetic process; thyroid hormone metabolic process; cuticle development; multicellular organism growth; thyroid gland development; bone mineralization; cytokine-mediated signaling pathway; response to virus; fertilization; response to oxidative stress
DUOXA1protein transport
DUOXA2protein transport
DUPD1protein dephosphorylation
DUS3LtRNA processing
DUSP10negative regulation of stress-activated MAPK cascade; negative regulation of respiratory burst involved in inflammatory response; negative regulation of JNK cascade; regulation of innate immune response; inactivation of MAPK activity; regulation of adaptive immune response; protein dephosphorylation; JNK cascade; negative regulation of JUN kinase activity; response to lipopolysaccharide; response to organic substance; response to stress
DUSP13protein dephosphorylation; meiosis; spermatogenesis
DUSP16protein dephosphorylation; inactivation of MAPK activity; dephosphorylation; MAPK phosphatase export from nucleus, leptomycin B sensitive; MAPK export from nucleus
DUSP21peptidyl-tyrosine dephosphorylation
DUSP22multicellular organismal development; cell proliferation; regulation of cell proliferation; positive regulation of JNK cascade; transforming growth factor beta receptor signaling pathway; apoptotic process; protein dephosphorylation; inactivation of MAPK activity
DUSP27protein dephosphorylation
DUSP3toll-like receptor 4 signaling pathway; positive regulation of mitotic cell cycle; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; Toll signaling pathway; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; in utero embryonic development; inactivation of MAPK activity; TRIF-dependent toll-like receptor signaling pathway; innate immune response; negative regulation of MAPK cascade; negative regulation of JNK cascade; nerve growth factor receptor signaling pathway; negative regulation of T cell receptor signaling pathway; negative regulation of T cell activation; stress-activated MAPK cascade; negative regulation of ERK1 and ERK2 cascade; peptidyl-tyrosine dephosphorylation
DUSP4nerve growth factor receptor signaling pathway; MAPK cascade; inactivation of MAPK activity; endoderm formation; toll-like receptor signaling pathway; stress-activated MAPK cascade; innate immune response; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; response to organic substance; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; protein dephosphorylation; Toll signaling pathway
DUSP5endoderm formation; negative regulation of transcription, DNA-dependent; peptidyl-tyrosine dephosphorylation; protein dephosphorylation; inactivation of MAPK activity
DUSP6nerve growth factor receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; regulation of fibroblast growth factor receptor signaling pathway; response to drug; regulation of endodermal cell fate specification; positive regulation of apoptotic process; innate immune response; negative regulation of protein phosphorylation; stress-activated MAPK cascade; response to nitrosative stress; regulation of heart growth; negative regulation of ERK1 and ERK2 cascade; response to growth factor stimulus; toll-like receptor 4 signaling pathway; peptidyl-tyrosine dephosphorylation; inactivation of MAPK activity; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; Toll signaling pathway; dorsal/ventral pattern formation; response to organic cyclic compound; cell differentiation; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway
DUSP7stress-activated MAPK cascade; nerve growth factor receptor signaling pathway; toll-like receptor signaling pathway; innate immune response; negative regulation of MAP kinase activity; TRIF-dependent toll-like receptor signaling pathway; peptidyl-tyrosine dephosphorylation; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; Toll signaling pathway; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; inactivation of MAPK activity
DUTnucleobase-containing small molecule metabolic process; nucleobase-containing compound metabolic process; pyrimidine base metabolic process; DNA replication; nucleotide metabolic process; small molecule metabolic process; dUTP metabolic process; pyrimidine nucleoside biosynthetic process
DUXA-
DVL1receptor clustering; protein localization to microtubule; intracellular signal transduction; positive regulation of transcription, DNA-dependent; collateral sprouting; axon extension; dendrite morphogenesis; synapse organization; convergent extension; canonical Wnt receptor signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway; prepulse inhibition; skeletal muscle acetylcholine-gated channel clustering; cochlea morphogenesis; planar cell polarity pathway involved in neural tube closure; positive regulation of canonical Wnt receptor signaling pathway; regulation of neurotransmitter levels; protein localization to nucleus; negative regulation of protein phosphorylation; transcription from RNA polymerase II promoter; negative regulation of protein kinase activity; signal transduction; neurotransmitter secretion; multicellular organismal development; axon guidance; heart development; neuromuscular junction development; positive regulation of neuron projection development; neural tube dev
DYM-
DYNC1H1microtubule-based movement; mitotic spindle organization; stress granule assembly; cytoplasmic mRNA processing body assembly; G2/M transition of mitotic cell cycle; mitotic cell cycle; transport
DYNC1I1vesicle transport along microtubule; transport
DYNC1LI2transport
DYNC2LI1multicellular organismal development; determination of left/right symmetry; cell projection organization; cilium assembly
DYNLL1interspecies interaction between organisms; negative regulation of phosphorylation; actin cytoskeleton organization; microtubule-based process; apoptotic process; transport; regulation of transcription, DNA-dependent; mitotic cell cycle; G2/M transition of mitotic cell cycle; anatomical structure morphogenesis; activation of pro-apoptotic gene products; induction of apoptosis by intracellular signals; female gamete generation
DYNLRB2transport; microtubule-based movement
DYNLT3cell cycle; transport; cell division; regulation of mitotic cell cycle; mitosis
DYRK1Aprotein autophosphorylation; protein phosphorylation; peptidyl-tyrosine phosphorylation; mitotic cell cycle; nervous system development
DYRK1Bpositive regulation of transcription, DNA-dependent; myoblast fusion; protein phosphorylation
DYRK3protein phosphorylation; erythrocyte differentiation
DYRK4protein phosphorylation
DYSF-
DYX1C1nervous system development; regulation of proteasomal protein catabolic process; neuron migration; regulation of intracellular estrogen receptor signaling pathway
DZIP1multicellular organismal development; germ cell development; spermatogenesis; cell differentiation
DZIP1L-
DZIP3protein polyubiquitination
E2F2G1 phase of mitotic cell cycle; mitotic cell cycle; regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter; apoptotic process; regulation of cell cycle
E2F6regulation of transcription involved in G1/S phase of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; cell cycle
E2F7cell cycle; negative regulation of cell proliferation
E2F8cell cycle
E4F1cell proliferation; regulation of mitotic cell cycle, embryonic; embryo development; cell division; regulation of cell cycle process; regulation of growth; interspecies interaction between organisms; mitosis; cell cycle; regulation of transcription, DNA-dependent; DNA replication; negative regulation of transcription from RNA polymerase II promoter; mitotic cell cycle arrest
EAF1regulation of transcription, DNA-dependent
EAPPnegative regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of cell proliferation
EBF1multicellular organismal development; positive regulation of transcription, DNA-dependent
EBF2multicellular organismal development; regulation of transcription, DNA-dependent
EBNA1BP2ribosome biogenesis
ECDregulation of transcription, DNA-dependent; regulation of glycolysis; transcription from RNA polymerase II promoter
ECE2heart development; proteolysis; cell-cell signaling; brain development; cardioblast differentiation; peptide hormone processing
ECEL1intracellular signal transduction; proteolysis; neuropeptide signaling pathway; metabolic process
ECHDC1-
ECHDC2fatty acid metabolic process; lipid metabolic process
ECHS1fatty acid metabolic process; fatty acid beta-oxidation; cellular lipid metabolic process; small molecule metabolic process
ECI1fatty acid beta-oxidation; fatty acid metabolic process; cellular lipid metabolic process; small molecule metabolic process
ECM1ossification; positive regulation of endothelial cell proliferation; signal transduction; negative regulation of peptidase activity; negative regulation of bone mineralization; biomineral tissue development; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of angiogenesis
ECT2Lregulation of Rho protein signal transduction
EDA2Repidermis development; embryo development; cell differentiation; tumor necrosis factor-mediated signaling pathway; positive regulation of JNK cascade; positive regulation of NF-kappaB transcription factor activity
EDARhair follicle development; signal transduction; multicellular organismal development; epidermis development; cell differentiation; positive regulation of NF-kappaB import into nucleus; odontogenesis of dentin-containing tooth; pigmentation; apoptotic process; salivary gland cavitation
EDARADDcell differentiation; multicellular organismal development; signal transduction; hair follicle development; odontogenesis of dentin-containing tooth; trachea gland development
EDC4gene expression; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; RNA metabolic process; mRNA metabolic process; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
EDDM3Bspermatid development
EDEM1protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification; endoplasmic reticulum unfolded protein response; ER-associated protein catabolic process; protein folding; response to unfolded protein; activation of signaling protein activity involved in unfolded protein response
EDEM3protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process; proteasomal ubiquitin-dependent protein catabolic process; response to unfolded protein; protein folding; glycoprotein catabolic process
EDIL3multicellular organismal development; positive regulation of cell-substrate adhesion; cell adhesion
EDN3regulation of developmental pigmentation; peptide hormone secretion; neural crest cell migration; positive regulation of leukocyte chemotaxis; regulation of systemic arterial blood pressure by endothelin; signal transduction; cell surface receptor signaling pathway; cell-cell signaling; multicellular organismal development; blood circulation; positive regulation of cell proliferation; positive regulation of heart rate; artery smooth muscle contraction; vein smooth muscle contraction; regulation of vasoconstriction; neuron differentiation; melanocyte differentiation; regulation of cell migration; neutrophil chemotaxis; vasoconstriction; positive regulation of MAP kinase activity; positive regulation of mitosis; positive regulation of hormone secretion; negative regulation of hormone secretion; regulation of neurotransmitter secretion; inositol phosphate-mediated signaling
EDNRApositive regulation of protein phosphorylation; histamine secretion; response to hypoxia; in utero embryonic development; response to lipopolysaccharide; patterning of blood vessels; regulation of epithelial cell proliferation; positive regulation of neutrophil chemotaxis; cellular response to mechanical stimulus; positive regulation of ERK1 and ERK2 cascade; head development; maternal process involved in parturition; positive regulation of calcium ion transport; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of inflammatory response; smooth muscle contraction; smooth muscle cell proliferation; fibroblast proliferation; response to morphine; penile erection; negative regulation of apoptotic process; positive regulation of odontogenesis; vasoconstriction; specification of segmental identity, mandibular segment; negative regulation of cAMP biosynthetic pr
EEA1early endosome to late endosome transport; synaptic vesicle to endosome fusion; vesicle fusion; endocytosis
EEF1A2translation; anti-apoptosis; response to inorganic substance
EEF1Dtranslation; translational elongation; signal transduction; gene expression; positive regulation of I-kappaB kinase/NF-kappaB cascade; cellular protein metabolic process
EEF1E1tRNA aminoacylation for protein translation; positive regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of apoptotic process; gene expression; negative regulation of cell proliferation
EEFSECtranslational elongation; GTP catabolic process; selenocysteine incorporation
EEPD1DNA repair
EFCAB1-
EFCAB13-
EFCAB2-
EFCAB6regulation of transcription, DNA-dependent
EFEMP1epidermal growth factor receptor signaling pathway; regulation of transcription, DNA-dependent; visual perception; peptidyl-tyrosine phosphorylation; negative regulation of chondrocyte differentiation
EFEMP2blood coagulation
EFHC1-
EFHD1neuron projection development
EFNA3cell-cell signaling; ephrin receptor signaling pathway
EFNA4cell-cell signaling
EFNB3ephrin receptor signaling pathway; interspecies interaction between organisms; axon choice point recognition; cell differentiation; adult walking behavior; nervous system development; multicellular organismal development; cell-cell signaling
EFScell adhesion; intracellular signal transduction
EFTUD2nuclear mRNA splicing, via spliceosome; GTP catabolic process; mRNA processing; RNA splicing; gene expression
EGFLAMpeptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; positive regulation of cell-substrate adhesion; extracellular matrix organization
EGFRpositive regulation of fibroblast proliferation; protein autophosphorylation; positive regulation of DNA replication; positive regulation of DNA repair; positive regulation of nitric oxide biosynthetic process; positive regulation of MAP kinase activity; negative regulation of apoptotic process; activation of phospholipase A2 activity by calcium-mediated signaling; positive regulation of phosphorylation; digestive tract morphogenesis; positive regulation of epithelial cell proliferation; regulation of peptidyl-tyrosine phosphorylation; regulation of nitric-oxide synthase activity; protein insertion into membrane; positive regulation of protein kinase B signaling cascade; morphogenesis of an epithelial fold; response to UV-A; ossification; negative regulation of epidermal growth factor receptor signaling pathway; cell morphogenesis; embryonic placenta development; hair follicle development; response to stress; signal transduction; cell surface receptor signaling pathway; transmembrane receptor protein tyrosine
EGR1regulation of long-term neuronal synaptic plasticity; type I interferon-mediated signaling pathway; transcription from RNA polymerase II promoter; interleukin-1-mediated signaling pathway; cellular response to gamma radiation; cellular response to heparin; cellular response to mycophenolic acid; glomerular mesangial cell proliferation; positive regulation of glomerular metanephric mesangial cell proliferation; negative regulation of canonical Wnt receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; learning or memory; response to glucose stimulus; cytokine-mediated signaling pathway; T cell differentiation; BMP signaling pathway; response to insulin stimulus; regulation of protein sumoylation
EGR2Schwann cell differentiation; regulation of neuronal synaptic plasticity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; fat cell differentiation; myelination; brain segmentation; response to insulin stimulus; regulation of ossification; rhombomere 5 formation; rhombomere 3 formation; facial nerve structural organization; rhombomere 3 development; motor axon guidance; rhythmic behavior; learning or memory; peripheral nervous system development; brain development; protein export from nucleus; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
EGR4regulation of transcription, DNA-dependent; positive regulation of cell proliferation
EHBP1-
EHD1low-density lipoprotein particle clearance; endocytic recycling; positive regulation of cholesterol storage; blood coagulation; endocytosis; intracellular protein transport; cholesterol homeostasis; protein homooligomerization
EHMT1histone H3-K9 methylation; embryo development; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; chromatin modification; histone H3-K27 methylation; negative regulation of transcription, DNA-dependent; histone lysine methylation; peptidyl-lysine dimethylation; peptidyl-lysine monomethylation; histone methylation
EID2Bcell differentiation; regulation of transcription, DNA-dependent; multicellular organismal development; muscle organ development
EIF1AD-
EIF2AK1negative regulation of cell proliferation; response to external stimulus; negative regulation of hemoglobin biosynthetic process; negative regulation of translation; protein autophosphorylation; protoporphyrinogen IX metabolic process; negative regulation of translational initiation by iron; response to stress; regulation of eIF2 alpha phosphorylation by heme
EIF2AK3fat cell differentiation; protein autophosphorylation; bone mineralization; insulin-like growth factor receptor signaling pathway; protein homooligomerization; response to endoplasmic reticulum stress; SREBP-mediated signaling pathway; positive regulation of protein binding; negative regulation of translational initiation in response to stress; negative regulation of myelination; insulin secretion; endoplasmic reticulum unfolded protein response; endocrine pancreas development; positive regulation of signal transduction; activation of cysteine-type endopeptidase activity involved in apoptotic process; protein phosphorylation; calcium-mediated signaling; chondrocyte development; ossification; virus-infected cell apoptosis; response to stress; ER overload response; response to unfolded protein; skeletal system development; regulation of fatty acid metabolic process; endoplasmic reticulum organization; activation of signaling protein activity involved in unfolded protein response; lactation; negative regulation
EIF2AK4regulation of translational initiation; negative regulation of translation; cellular response to starvation; endoplasmic reticulum unfolded protein response; protein phosphorylation; regulation of translational initiation in response to stress
EIF2B1cellular response to stimulus; cellular protein metabolic process; cellular metabolic process; response to peptide hormone stimulus; oligodendrocyte development; gene expression; response to glucose stimulus; response to heat; translation; translational initiation; regulation of translational initiation
EIF2B2myelination; cellular protein metabolic process; cellular response to stimulus; ovarian follicle development; translation; translational initiation; regulation of translational initiation; central nervous system development; response to heat; oligodendrocyte development; response to peptide hormone stimulus; cellular metabolic process; response to glucose stimulus; gene expression
EIF2B4negative regulation of translational initiation; ovarian follicle development; translation; translational initiation; regulation of translation; response to heat; response to glucose stimulus; gene expression; oligodendrocyte development; negative regulation of translational initiation in response to stress; myelination; response to peptide hormone stimulus; cellular metabolic process; cellular protein metabolic process; cellular response to stimulus
EIF2Dtranslational initiation; intracellular protein transport
EIF2S1gene expression; protein autophosphorylation; cellular protein metabolic process; regulation of translational initiation in response to stress; endoplasmic reticulum unfolded protein response; activation of signaling protein activity involved in unfolded protein response; regulation of translation; translational initiation; translation
EIF3Acellular protein metabolic process; translational initiation; translation; formation of translation initiation complex; gene expression
EIF3Btranslation; translational initiation; regulation of translational initiation; gene expression; cellular protein metabolic process
EIF3Dcellular protein metabolic process; gene expression; translational initiation; translation; formation of translation initiation complex
EIF3Htranslation; translational initiation; regulation of translational initiation; gene expression; cellular protein metabolic process
EIF3Ltranslational initiation
EIF3Mtranslational initiation
EIF4A1cellular protein metabolic process; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; nuclear-transcribed mRNA poly(A) tail shortening; translation; translational initiation; gene expression; RNA metabolic process; mRNA metabolic process; cytokine-mediated signaling pathway; organ regeneration
EIF4ERNA metabolic process; gene expression; insulin receptor signaling pathway; regulation of translation; translational initiation; translation; mRNA export from nucleus; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; G1/S transition of mitotic cell cycle; mRNA metabolic process; cytokine-mediated signaling pathway; cellular protein metabolic process; interspecies interaction between organisms; positive regulation of mitotic cell cycle
EIF4E2regulation of translation; cytokine-mediated signaling pathway; translation
EIF4EBP1gene expression; G1/S transition of mitotic cell cycle; translation; translational initiation; insulin receptor signaling pathway; negative regulation of protein complex assembly; TOR signaling cascade; cellular protein metabolic process; positive regulation of mitotic cell cycle; negative regulation of translational initiation
EIF4G1cell death; cellular protein metabolic process; interspecies interaction between organisms; mRNA metabolic process; RNA metabolic process; gene expression; insulin receptor signaling pathway; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of translational initiation; translational initiation; translation; nuclear-transcribed mRNA poly(A) tail shortening; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; cytokine-mediated signaling pathway
EIF4G2cell death; cytokine-mediated signaling pathway; RNA metabolic process; regulation of translational initiation; translational initiation; translation; cell cycle arrest
EIF4G3interspecies interaction between organisms; cytokine-mediated signaling pathway; translation; regulation of translational initiation; RNA metabolic process
EIF5A2positive regulation of translational elongation; polyamine homeostasis; protein transport; post-translational protein modification; mRNA transport; cellular protein metabolic process; positive regulation of translational termination; positive regulation of cell proliferation; peptidyl-lysine modification to hypusine; translational frameshifting; spermatogenesis
EIF5Btranslation; translational initiation; regulation of translational initiation; gene expression; cellular protein metabolic process
ELAC1tRNA 3'-trailer cleavage; tRNA processing
ELAVL1gene expression; 3'-UTR-mediated mRNA stabilization; mRNA stabilization; positive regulation of translation; RNA metabolic process; multicellular organismal development; mRNA metabolic process
ELAVL3multicellular organismal development; nervous system development; cell differentiation
ELAVL4RNA processing; mRNA processing
ELF1positive regulation of transcription from RNA polymerase II promoter; negative regulation of T cell receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of cytokine production
ELF2regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent
ELF3mammary gland involution; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; epithelial cell differentiation; extracellular matrix organization; anatomical structure morphogenesis; epidermis development; multicellular organismal development; inflammatory response; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; blastocyst development; embryo development
ELF5transcription from RNA polymerase II promoter; ectoderm development; cell proliferation; mammary gland epithelial cell differentiation
ELFN2negative regulation of phosphatase activity
ELLregulation of transcription, DNA-dependent; in utero embryonic development; transcription from RNA polymerase II promoter; positive regulation of viral transcription; positive regulation of transcription elongation, DNA-dependent; viral reproduction; negative regulation of phosphatase activity; gene expression; transcription elongation from RNA polymerase II promoter
ELL3transcription elongation, DNA-dependent; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription elongation, DNA-dependent; regulation of transcription, DNA-dependent; transcription elongation from RNA polymerase II promoter
ELMO1cellular component movement; viral reproduction; apoptotic process; phagocytosis, engulfment; actin cytoskeleton organization; Rac protein signal transduction; regulation of defense response to virus by virus
ELMO3phagocytosis; apoptotic process
ELMOD3phagocytosis
ELNblood circulation; organ morphogenesis; cell proliferation; respiratory gaseous exchange
ELOVL4triglyceride biosynthetic process; fatty acid elongation, saturated fatty acid; long-chain fatty-acyl-CoA biosynthetic process; detection of visible light; fatty acid biosynthetic process; very long-chain fatty acid biosynthetic process; cellular lipid metabolic process; small molecule metabolic process
ELOVL7triglyceride biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; very long-chain fatty acid biosynthetic process; long-chain fatty-acyl-CoA biosynthetic process; fatty acid elongation, polyunsaturated fatty acid; fatty acid elongation, saturated fatty acid; fatty acid biosynthetic process
ELSPBP1single fertilization
EMC1-
EMCN-
EMILIN1extracellular matrix organization; positive regulation of cell-substrate adhesion; cell adhesion
EMILIN2cell adhesion
EMILIN3-
EML1-
EML2visual perception; sensory perception of sound
EML3-
EML4mitosis; microtubule-based process
EMP1multicellular organismal development; cell proliferation; epidermis development; cell growth
EMP2cell proliferation
EMSYDNA repair; chromatin modification; regulation of transcription, DNA-dependent
EN1pigmentation; positive regulation of transcription from RNA polymerase II promoter; neuron development; skeletal system development; multicellular organismal development; anatomical structure morphogenesis; dorsal/ventral pattern formation; proximal/distal pattern formation; midbrain development; hindbrain development; midbrain-hindbrain boundary development; embryonic forelimb morphogenesis
ENAMbone mineralization; odontogenesis
ENC1multicellular organismal development; nervous system development
ENDOGpositive regulation of apoptotic process; response to antibiotic; response to tumor necrosis factor; DNA fragmentation involved in apoptotic nuclear change; in utero embryonic development
ENDOUfemale pregnancy; immune response; proteolysis
ENGASEmetabolic process
ENKUR-
ENO1carbohydrate metabolic process; negative regulation of transcription, DNA-dependent; small molecule metabolic process; negative regulation of cell growth; response to virus; glycolysis; gluconeogenesis; glucose metabolic process; negative regulation of transcription from RNA polymerase II promoter
ENO2gluconeogenesis; glycolysis; small molecule metabolic process; carbohydrate metabolic process; glucose metabolic process
ENO3carbohydrate metabolic process; glucose metabolic process; gluconeogenesis; glycolysis; aging; response to drug; skeletal muscle tissue regeneration; small molecule metabolic process
ENOX1rhythmic process; electron transport chain; transport
ENPEPangiogenesis; angiotensin catabolic process in blood; regulation of systemic arterial blood pressure by renin-angiotensin; proteolysis; cell-cell signaling; metabolic process; cell proliferation; cell migration; glomerulus development
ENPP1riboflavin metabolic process; generation of precursor metabolites and energy; vitamin metabolic process; water-soluble vitamin metabolic process; cellular response to insulin stimulus; small molecule metabolic process; negative regulation of fat cell differentiation; negative regulation of glycogen biosynthetic process; negative regulation of glucose import; negative regulation of insulin receptor signaling pathway; bone remodeling; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; immune response; negative regulation of protein autophosphorylation; biomineral tissue development; sequestering of triglyceride; cellular phosphate ion homeostasis; inorganic diphosphate transport; regulation of bone mineralization; negative regulation of cell growth; negative regulation of ossification; nucleoside triphosphate catabolic process; phosphate-containing compound metabolic process
ENPP2immune response; phosphatidylcholine catabolic process; regulation of cell migration; lipid catabolic process; G-protein coupled receptor signaling pathway; chemotaxis; cellular component movement; phosphate-containing compound metabolic process
ENPP3phosphate-containing compound metabolic process; inorganic diphosphate transport; nucleoside triphosphate catabolic process; immune response
ENPP5cell communication
ENPP6choline metabolic process; lipid catabolic process
ENPP7negative regulation of cell proliferation; negative regulation of DNA replication; glycosphingolipid metabolic process; sphingomyelin metabolic process; sphingolipid metabolic process; small molecule metabolic process
ENTHD1-
ENTHD2-
ENTPD2G-protein coupled receptor signaling pathway; purine ribonucleoside diphosphate catabolic process; platelet activation
ENTPD4UDP catabolic process
ENTPD5cell growth; protein N-linked glycosylation; ATP metabolic process; 'de novo' posttranslational protein folding; regulation of phosphatidylinositol 3-kinase cascade; cell proliferation; metabolic process; glycolysis
ENTPD6response to calcium ion; response to magnesium ion
ENTPD7-
ENTPD8nucleoside diphosphate biosynthetic process; nucleoside monophosphate biosynthetic process
EOGT-
EOMESmesodermal to mesenchymal transition involved in gastrulation; endoderm formation; mesoderm formation; endodermal cell fate specification; blastocyst development; trophectodermal cell differentiation; CD8-positive, alpha-beta T cell differentiation involved in immune response; multicellular organismal development; brain development; cerebral cortex neuron differentiation; positive regulation of cell differentiation; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cell differentiation involved in embryonic placenta development
EP300response to calcium ion; response to glucocorticoid stimulus; regulation of angiotensin metabolic process; positive regulation of sarcomere organization; regulation of androgen receptor signaling pathway; protein-DNA complex assembly; cellular response to hydrogen peroxide; response to fatty acid; skeletal muscle tissue development; heart development; nervous system development; cell cycle; apoptotic process; regulation of transcription, DNA-dependent; positive regulation of protein phosphorylation; liver development; somitogenesis; response to hypoxia; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cellular metabolic process; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; response to drug; positive regulation of protein import into nucleus, translocation; positive regulation of collagen biosynthetic process; response to retinoic acid; positive regulation of protein binding; response to cobalt ion; positive regu
EP400regulation of transcription, DNA-dependent; histone H2A acetylation; histone H4 acetylation; chromatin modification
EPAS1embryonic placenta development; erythrocyte differentiation; hemopoiesis; visual perception; multicellular organismal development; signal transduction; mitochondrion organization; response to oxidative stress; transcription from RNA polymerase II promoter; regulation of heart rate; blood vessel remodeling; response to hypoxia; angiogenesis; myoblast cell fate commitment; cell maturation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; surfactant homeostasis; norepinephrine metabolic process; lung development; cell differentiation
EPB41positive regulation of protein binding; blood circulation; actin cytoskeleton organization; cortical actin cytoskeleton organization
EPB41L1synaptic transmission; cortical actin cytoskeleton organization
EPB41L3cortical actin cytoskeleton organization
EPB41L4A-
EPB41L4B-
EPB41L5-
EPB42regulation of cell shape; peptide cross-linking; erythrocyte maturation
EPC1negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; chromatin modification; regulation of growth; histone H4 acetylation; histone H2A acetylation; negative regulation of gene expression, epigenetic; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent
EPDR1cell-matrix adhesion
EPG5autophagy
EPHA1positive regulation of cell proliferation; activation of Rho GTPase activity; peptidyl-tyrosine phosphorylation; positive regulation of cell migration; negative regulation of cell migration; regulation of Rac GTPase activity; positive regulation of stress fiber assembly; protein autophosphorylation; positive regulation of angiogenesis; substrate adhesion-dependent cell spreading; cell adhesion; negative regulation of protein kinase activity; positive regulation of cell-matrix adhesion; cell surface receptor signaling pathway
EPHA10-
EPHA2blood vessel development; skeletal system development; positive regulation of establishment of protein localization in plasma membrane; response to growth factor stimulus; regulation of ERK1 and ERK2 cascade; lens fiber cell morphogenesis; branching involved in mammary gland duct morphogenesis; cell chemotaxis; notochord cell development; negative regulation of protein kinase B signaling cascade; axial mesoderm formation; ephrin receptor signaling pathway; bone remodeling; regulation of angiogenesis; regulation of blood vessel endothelial cell migration; protein kinase B signaling cascade; regulation of cell adhesion mediated by integrin; vasculogenesis; osteoblast differentiation; apoptotic process; cell adhesion; multicellular organismal development; regulation of lamellipodium assembly; notochord formation; neural tube development; neuron differentiation; keratinocyte differentiation; osteoclast differentiation; activation of Rac GTPase activity; mammary gland epithelial cell proliferation; tail morphogene
EPHA3cell migration; fasciculation of motor neuron axon; fasciculation of sensory neuron axon; cellular response to retinoic acid; fever generation; apoptotic process; cell adhesion; regulation of epithelial to mesenchymal transition; positive regulation of neuron projection development; regulation of Rho GTPase activity; response to lipopolysaccharide; regulation of microtubule cytoskeleton organization; regulation of focal adhesion assembly; ephrin receptor signaling pathway; response to cytokine stimulus; regulation of actin cytoskeleton organization
EPHA5nervous system development; regulation of insulin secretion involved in cellular response to glucose stimulus; dendritic spine morphogenesis; neuron development; ephrin receptor signaling pathway; regulation of actin cytoskeleton organization; positive regulation of CREB transcription factor activity; regulation of Rac GTPase activity; hippocampus development; cAMP-mediated signaling; axon guidance
EPHA7regulation of ERK1 and ERK2 cascade; multicellular organismal development; axon guidance; brain development; phosphorylation; regulation of cell-cell adhesion; retinal ganglion cell axon guidance; regulation of protein autophosphorylation; regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of neuron apoptosis; ephrin receptor signaling pathway; branching morphogenesis of a nerve; negative chemotaxis; regulation of peptidyl-tyrosine phosphorylation
EPHA8protein autophosphorylation; substrate-dependent cell migration; multicellular organismal development; nervous system development; axon guidance; neuron remodeling; regulation of cell adhesion; neuron projection development; regulation of cell adhesion mediated by integrin; positive regulation of MAPK cascade; positive regulation of phosphatidylinositol 3-kinase activity; ephrin receptor signaling pathway
EPHB2commissural neuron axon guidance; urogenital system development; dendritic spine morphogenesis; dendritic spine development; palate development; positive regulation of synapse assembly; regulation of body fluid levels; ephrin receptor signaling pathway; inner ear morphogenesis; corpus callosum development; peptidyl-tyrosine phosphorylation; phosphorylation; axonal fasciculation; axon guidance; nervous system development; multicellular organismal development; protein phosphorylation; angiogenesis
EPHB3signal transduction; angiogenesis; urogenital system development; multicellular organismal development; dendritic spine morphogenesis; dendritic spine development; palate development; positive regulation of synapse assembly; regulation of axonogenesis; digestive tract morphogenesis; thymus development; ephrin receptor signaling pathway; protein autophosphorylation; regulation of Cdc42 GTPase activity; regulation of Rac GTPase activity; retinal ganglion cell axon guidance; regulation of cell-cell adhesion; corpus callosum development; central nervous system projection neuron axonogenesis; cell migration; axonal fasciculation; axon guidance; nervous system development; substrate adhesion-dependent cell spreading
EPHB4multicellular organismal development; ephrin receptor signaling pathway; protein autophosphorylation; cell adhesion; cell migration involved in sprouting angiogenesis; angiogenesis; heart morphogenesis
EPHB6ephrin receptor signaling pathway
EPHX1aromatic compound catabolic process; response to organic cyclic compound; response to toxin
EPHX2drug metabolic process; xenobiotic metabolic process; cellular calcium ion homeostasis; inflammatory response; regulation of blood pressure; response to toxin; reactive oxygen species metabolic process; positive regulation of vasodilation; aromatic compound catabolic process
EPHX4-
EPN3-
EPORelevation of cytosolic calcium ion concentration; signal transduction; brain development; heart development; embryo development; cellular response to erythropoietin; decidualization
EPRStRNA aminoacylation for protein translation; glutamyl-tRNA aminoacylation; prolyl-tRNA aminoacylation; protein complex assembly; gene expression
EPS15clathrin coat assembly; epidermal growth factor receptor signaling pathway; protein transport; vesicle organization; endocytic recycling; negative regulation of epidermal growth factor receptor signaling pathway; cell proliferation
EPS15L1epidermal growth factor receptor signaling pathway; endocytosis; negative regulation of epidermal growth factor receptor signaling pathway
EPS8cell proliferation; epidermal growth factor receptor signaling pathway; signal transduction
EPS8L1-
EPS8L2-
EPS8L3-
EPSTI1-
EPXhydrogen peroxide catabolic process; response to oxidative stress
EPYCfemale pregnancy
EQTN-
ERAL1ribosomal small subunit assembly; ribosome biogenesis
ERAP2antigen processing and presentation of endogenous peptide antigen via MHC class I; regulation of blood pressure; proteolysis; antigen processing and presentation of peptide antigen via MHC class I
ERBB2protein autophosphorylation; phosphatidylinositol-mediated signaling; sympathetic nervous system development; response to axon injury; positive regulation of epithelial cell proliferation; mammary gland involution; estrus; regulation of ERK1 and ERK2 cascade; negative regulation of apoptotic process; motor axon guidance; positive regulation of Ras protein signal transduction; response to progesterone stimulus; regulation of microtubule-based process; negative regulation of immature T cell proliferation in thymus; wound healing; response to drug; myelination; positive regulation of Rho GTPase activity; mammary gland development; positive regulation of cell growth; signal transduction by phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase cascade; glial cell differentiation; cell proliferation; positive regulation of transcription from RNA polymerase III promoter; neuromuscular junction development; skeletal muscle tissue development; heart development; p
ERBB2IPcell growth; integrin-mediated signaling pathway; epidermal growth factor receptor signaling pathway; intermediate filament cytoskeleton organization; basal protein localization; signal transduction; cell adhesion; cell cycle; establishment or maintenance of epithelial cell apical/basal polarity
ERBB3positive regulation of glucose import; phosphatidylinositol 3-kinase cascade; positive regulation of phosphatidylinositol 3-kinase cascade; cranial nerve development; cellular response to insulin stimulus; wound healing; regulation of cell proliferation; odontogenesis; response to drug; negative regulation of neuron apoptosis; tongue development; mammary gland involution; negative regulation of secretion; neuron apoptosis; negative regulation of signal transduction; positive regulation of protein tyrosine kinase activity; endocardial cushion development; negative regulation of cell adhesion; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; axonogenesis; peripheral nervous system development; heart development; skeletal muscle tissue development; circadian rhythm; Schwann cell differentiation
ERBB4positive regulation of STAT protein import into nucleus; positive regulation of ERK1 and ERK2 cascade; cardiac muscle tissue regeneration; mammary gland alveolus development; positive regulation of cardiac muscle cell proliferation; mammary gland epithelial cell differentiation; lactation; central nervous system morphogenesis; telencephalon development; peptidyl-tyrosine phosphorylation; cell migration; embryonic pattern specification; negative regulation of cell proliferation; positive regulation of cell proliferation; cell proliferation; positive regulation of epithelial cell proliferation; heart development; nervous system development; multicellular organismal development; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; apoptotic process; positive regulation of protein phosphorylation; neural crest cell migration; regulation of cell migration; synapse maturation; protein autophosphorylation; positive regulation of glucose import; positive regulation of transcription,
ERC1positive regulation of NF-kappaB transcription factor activity; regulation of transcription, DNA-dependent; I-kappaB phosphorylation; multicellular organismal development; protein transport; retrograde transport, endosome to Golgi; positive regulation of anti-apoptosis
ERCC1multicellular organism growth; nucleotide-excision repair, DNA damage removal; chromosome organization; embryonic organ development; oogenesis; isotype switching; negative regulation of apoptotic process; post-embryonic hemopoiesis; negative regulation of telomere maintenance; multicellular organismal aging; response to X-ray; response to sucrose stimulus; UV protection; response to abiotic stimulus; male gonad development; cell proliferation; response to nutrient; germ cell development; pyrimidine dimer repair by nucleotide-excision repair; replicative cell aging; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; double-strand break repair; DNA recombination; mitotic recombination; syncytium formation; response to oxidative stress; spermatogenesis
ERCC2nucleotide-excision repair, DNA damage removal; hemopoietic stem cell differentiation; positive regulation of viral transcription; hair follicle maturation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; interspecies interaction between organisms; transcription initiation from RNA polymerase I promoter; response to oxidative stress; induction of apoptosis; protein phosphorylation; mRNA capping; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; positive regulation of DNA binding; transcription from RNA polymerase I promoter; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; nucleobase-containing compound metabolic process; in utero embryonic development; response to hypoxia; cell cyc
ERCC3transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; mRNA capping; protein phosphorylation; termination of RNA polymerase I transcription; transcription elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; induction of apoptosis; response to oxidative stress; protein localization; response to UV; UV protection; gene expression; viral reproduction; nucleotide-excision repair, DNA incision; hair cell differentiation; interspecies interaction between organisms; positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; DNA repair; DNA topological change; ATP catabolic process; response to hypoxia; nucleotide-excision repair, DNA damage removal; nucleotide-excision repair, DNA duplex
ERCC4nucleotide-excision repair, DNA damage removal; double-strand break repair via homologous recombination; telomere maintenance; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; response to UV; UV protection; telomere maintenance via telomere shortening; negative regulation of telomere maintenance; nucleotide-excision repair, DNA incision; meiotic mismatch repair; resolution of meiotic recombination intermediates
ERCC6photoreceptor cell maintenance; positive regulation of transcription elongation, DNA-dependent; regulation of transcription elongation, DNA-dependent; response to gamma radiation; response to UV-B; response to X-ray; response to UV; DNA damage response, signal transduction resulting in induction of apoptosis; activation of JUN kinase activity; activation of JNKK activity; response to toxin; response to oxidative stress; transcription from RNA polymerase II promoter; pyrimidine dimer repair; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; response to superoxide; base-excision repair
ERCC6Lcell division; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle
ERCC6L2DNA repair
ERCC8protein autoubiquitination; positive regulation of DNA repair; proteasomal ubiquitin-dependent protein catabolic process; response to X-ray; protein polyubiquitination; DNA repair; transcription-coupled nucleotide-excision repair; nucleotide-excision repair; response to DNA damage stimulus; response to oxidative stress; response to UV
ERGIC1vesicle-mediated transport; ER to Golgi vesicle-mediated transport
ERI2-
ERICH3-
ERICH6-
ERLEC1ER-associated protein catabolic process
ERLIN2ER-associated protein catabolic process
ERMAP-
ERMP1ovarian follicle development; proteolysis
ERO1Aoxidation-reduction process; endoplasmic reticulum unfolded protein response; protein folding; protein modification process; protein thiol-disulfide exchange; transport; response to temperature stimulus; electron transport chain; chaperone mediated protein folding requiring cofactor; brown fat cell differentiation
ERO1Belectron transport chain; oxidation-reduction process; protein thiol-disulfide exchange; protein folding; transport
ERP27-
ERP44protein folding; response to stress; response to unfolded protein; glycoprotein metabolic process; cell redox homeostasis
ESCO1regulation of DNA replication; cell cycle; post-translational protein acetylation
ESDmetabolic process
ESF1regulation of transcription, DNA-dependent
ESPL1chromosome segregation; apoptotic process; proteolysis; cytokinesis; meiotic spindle organization; mitotic sister chromatid segregation; metabolic process; establishment of mitotic spindle localization; homologous chromosome segregation; positive regulation of mitotic metaphase/anaphase transition; negative regulation of sister chromatid cohesion
ESR2positive regulation of apoptotic process; vagina development; intracellular receptor mediated signaling pathway; intracellular estrogen receptor signaling pathway; negative regulation of cell growth; gene expression; negative regulation of signal transduction; brain development; cell-cell signaling; signal transduction; regulation of transcription, DNA-dependent; neuron migration; ovarian follicle development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of epithelial cell proliferation; positive regulation of sequence-specific DNA binding transcription factor activity; uterus development; prostate gland epithelium morphogenesis; epithelial cell maturation involved in prostate gland development; negative regulation of androgen receptor signaling pathway; steroid hormone mediated signaling pathway
ESRP2mRNA processing; regulation of RNA splicing
ESRRGgene expression; positive regulation of transcription, DNA-dependent
ESX1labyrinthine layer blood vessel development; labyrinthine layer morphogenesis; regulation of cell cycle; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; blood vessel development
ESYT1-
ESYT2-
ESYT3-
ETAA1-
ETFBrespiratory electron transport chain; transport; small molecule metabolic process
ETFDHtransport; response to oxidative stress; electron transport chain; respiratory electron transport chain; fatty acid beta-oxidation using acyl-CoA dehydrogenase; small molecule metabolic process
ETHE1sulfur amino acid metabolic process; sulfide oxidation, using sulfide:quinone oxidoreductase; small molecule metabolic process; sulfur amino acid catabolic process; cellular nitrogen compound metabolic process
ETS1PML body organization; response to hypoxia; transcription from RNA polymerase II promoter; anti-apoptosis; induction of apoptosis; response to laminar fluid shear stress; response to estradiol stimulus; positive regulation of erythrocyte differentiation; positive regulation of cell migration; pituitary gland development; hypothalamus development; regulation of extracellular matrix disassembly; response to mechanical stimulus; response to wounding; negative regulation of cell proliferation; positive regulation of cell proliferation; female pregnancy; immune response; angiogenesis involved in wound healing; positive regulation of angiogenesis; negative regulation of cell cycle; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to antibiotic; cell motility; positive regulation of cellular component movement; response to interleukin-1; cellular response to hydrogen peroxide; estrous cycle phase
ETV4negative regulation of mammary gland epithelial cell proliferation; regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; stem cell differentiation; motor axon guidance; regulation of branching involved in mammary gland duct morphogenesis
ETV5male germ-line stem cell division; regulation of transcription, DNA-dependent; cellular response to oxidative stress; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; regulation of branching involved in mammary gland duct morphogenesis; positive regulation of glial cell proliferation
ETV6regulation of transcription, DNA-dependent
ETV7organ morphogenesis; transcription from RNA polymerase II promoter
EVA1A-
EVA1C-
EVI2A-
EVI5cell division; multicellular organismal development; cell cycle; cell proliferation
EVI5L-
EVLnervous system development; axon guidance; actin polymerization or depolymerization; actin filament organization; cell surface receptor signaling pathway; organ morphogenesis; protein homotetramerization
EVPLepidermis development; peptide cross-linking; keratinocyte differentiation; keratinization
EVX1multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; embryo development ending in birth or egg hatching; regulation of transcription, DNA-dependent
EVX2multicellular organismal development; limb morphogenesis
EXD1nucleobase-containing compound metabolic process
EXD2nucleobase-containing compound metabolic process
EXO1humoral immune response mediated by circulating immunoglobulin; DNA repair; mismatch repair; meiosis; somatic hypermutation of immunoglobulin genes; isotype switching; DNA recombination
EXOC2protein transport; exocytosis
EXOC3L1peptide hormone secretion; exocytosis
EXOC4oligodendrocyte differentiation; positive regulation of calcium-mediated signaling; regulation of protein transport; membrane biogenesis; establishment of cell polarity; Golgi to transport vesicle transport; synaptic transmission; vesicle docking involved in exocytosis; protein targeting to membrane
EXOC6protein transport; vesicle docking involved in exocytosis
EXOC7exocytosis; protein transport
EXOC8protein transport; exocytosis
EXOSC10nuclear retention of unspliced pre-mRNA at the site of transcription; nuclear-transcribed mRNA catabolic process; nucleobase-containing compound metabolic process; RNA processing; cellular metabolic process; CUT catabolic process; histone mRNA catabolic process; nuclear polyadenylation-dependent rRNA catabolic process; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; maturation of 5.8S rRNA; nuclear mRNA surveillance
EXPH5positive regulation of exocytosis; multivesicular body sorting pathway; intracellular protein transport; positive regulation of protein secretion
EXT1cellular polysaccharide biosynthetic process; olfactory bulb development; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparan sulfate proteoglycan biosynthetic process; mesoderm development; endoderm development; brain development; gastrulation; signal transduction; glycosaminoglycan biosynthetic process; ossification; skeletal system development; axon guidance
EXTL1skeletal system development
EXTL3activation of signaling protein activity involved in unfolded protein response; positive regulation of cell growth; endoplasmic reticulum unfolded protein response
EYA1histone dephosphorylation; peptidyl-tyrosine dephosphorylation; protein sumoylation; positive regulation of DNA repair; chromatin modification; response to ionizing radiation; sensory perception of sound; multicellular organismal development; regulation of transcription, DNA-dependent; double-strand break repair; anatomical structure morphogenesis
EYA2mesodermal cell fate specification; peptidyl-tyrosine dephosphorylation; histone dephosphorylation; chromatin modification; striated muscle tissue development; multicellular organismal development; apoptotic process; regulation of transcription, DNA-dependent; DNA repair
EYA3double-strand break repair; positive regulation of DNA repair; peptidyl-tyrosine dephosphorylation; histone dephosphorylation; chromatin modification; response to ionizing radiation; anatomical structure morphogenesis; visual perception; multicellular organismal development; regulation of transcription, DNA-dependent
EYA4chromatin modification; anatomical structure morphogenesis; visual perception; multicellular organismal development; regulation of transcription, DNA-dependent; DNA repair
EYSresponse to stimulus; visual perception
EZH1peptidyl-lysine methylation; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; anatomical structure morphogenesis; chromatin modification
EZRactin filament bundle assembly; epithelial cell differentiation; membrane to membrane docking; regulation of cell shape; axon guidance; establishment or maintenance of apical/basal cell polarity; cytoskeletal anchoring at plasma membrane; leukocyte cell-cell adhesion
F10peptidyl-glutamic acid carboxylation; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; post-translational protein modification; positive regulation of cell migration; blood coagulation, extrinsic pathway; blood coagulation, intrinsic pathway; blood coagulation; proteolysis
F11positive regulation of fibrinolysis; plasminogen activation; regulation of blood coagulation; blood coagulation, intrinsic pathway; blood coagulation; proteolysis
F12zymogen activation; Factor XII activation; plasma kallikrein-kinin cascade; proteolysis; blood coagulation; blood coagulation, intrinsic pathway; positive regulation of plasminogen activation; protein processing; protein autoprocessing; positive regulation of blood coagulation; innate immune response; response to misfolded protein; positive regulation of fibrinolysis
F13A1platelet degranulation; blood coagulation; peptide cross-linking; platelet activation
F13Bblood coagulation
F2positive regulation of blood coagulation; blood coagulation; multicellular organismal development; cell surface receptor signaling pathway; acute-phase response; proteolysis; positive regulation of protein phosphorylation; positive regulation of cell proliferation; regulation of blood coagulation; positive regulation of cell growth; positive regulation of collagen biosynthetic process; fibrinolysis; post-translational protein modification; cellular protein metabolic process; negative regulation of proteolysis; negative regulation of astrocyte differentiation; leukocyte migration; positive regulation of release of sequestered calcium ion into cytosol; cytosolic calcium ion homeostasis; negative regulation of fibrinolysis; positive regulation of reactive oxygen species metabolic process; platelet activation; peptidyl-glutamic acid carboxylation; positive regulation of phosphatidylinositol 3-kinase cascade; negative regulation of platelet activation; response to wounding; regulation of cell shape; blood coagulat
F2Rpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of interleukin-6 secretion; positive regulation of interleukin-8 secretion; thrombin receptor signaling pathway; STAT protein import into nucleus; regulation of blood coagulation; platelet activation; death; positive regulation of phosphatidylinositol 3-kinase cascade; anatomical structure morphogenesis; response to wounding; negative regulation of cell proliferation; positive regulation of cell proliferation; blood coagulation; establishment of synaptic specificity at neuromuscular junction; platelet dense granule organization; tyrosine phosphorylation of STAT protein; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; inflammatory response; activation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of glomerular filt
F2RL1negative regulation of tumor necrosis factor-mediated signaling pathway; positive regulation of interleukin-6 secretion; positive regulation of interleukin-8 secretion; mature dendritic cell differentiation; negative regulation of chemokine secretion; negative regulation of JNK cascade; chemokine (C-C motif) ligand 2 secretion; neutrophil activation; regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of eosinophil degranulation; innate immune response; positive regulation of vasodilation; positive regulation of transcription from RNA polymerase II promoter; regulation of JNK cascade; positive regulation of Rho protein signal transduction; positive regulation of JNK cascade; interleukin-1 beta secretion; leukocyte migration; positive regulation of chemotaxis; positive regulation of positive chemotaxis; defense response to virus; positive regulation of phagocytosis, engulfment; establishment of endothelial barrier; positive regulation o
F2RL2blood coagulation; response to wounding; platelet activation; thrombin receptor signaling pathway
F2RL3thrombin receptor signaling pathway; positive regulation of release of sequestered calcium ion into cytosol; platelet activation; response to wounding; platelet dense granule organization; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; signal transduction; blood coagulation
F3positive regulation of platelet-derived growth factor receptor signaling pathway; response to temperature stimulus; positive regulation of smooth muscle cell migration; positive regulation of cell migration; response to estradiol stimulus; response to lipopolysaccharide; response to fluid shear stress; positive regulation of angiogenesis; positive regulation of positive chemotaxis; positive regulation of protein kinase B signaling cascade; response to low-density lipoprotein particle stimulus; cellular response to hydrogen peroxide; response to wounding; positive regulation of endothelial cell proliferation; activation of plasma proteins involved in acute inflammatory response; activation of blood coagulation via clotting cascade; anti-apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; aging; blood coagulation; blood coagulation, extrinsic pathway; response to mechanical stimulus
F5platelet degranulation; cell adhesion; platelet activation; blood circulation; blood coagulation
F7blood coagulation, extrinsic pathway; blood coagulation; proteolysis; circadian rhythm; response to hormone stimulus; positive regulation of platelet-derived growth factor receptor signaling pathway; response to organic cyclic compound; peptidyl-glutamic acid carboxylation; positive regulation of blood coagulation; positive regulation of cell migration; organ regeneration; response to nutrient levels; response to vitamin K; response to estrogen stimulus; post-translational protein modification; cellular protein metabolic process; positive regulation of positive chemotaxis; positive regulation of protein kinase B signaling cascade; response to growth hormone stimulus; positive regulation of leukocyte chemotaxis; anti-apoptosis
F8platelet degranulation; acute-phase response; cell adhesion; blood coagulation; blood coagulation, intrinsic pathway; platelet activation
F9cellular protein metabolic process; post-translational protein modification; peptidyl-glutamic acid carboxylation; blood coagulation, extrinsic pathway; blood coagulation, intrinsic pathway; blood coagulation; proteolysis
FAAH2-
FAAP100DNA repair
FABP1positive regulation of hydrolase activity; intestinal absorption; positive regulation of cell proliferation; organ morphogenesis; positive regulation of fatty acid beta-oxidation; cellular lipid metabolic process; small molecule metabolic process
FABP3fatty acid metabolic process; phosphatidylcholine biosynthetic process; negative regulation of cell proliferation; response to insulin stimulus; response to drug; response to fatty acid
FABP4cholesterol homeostasis; brown fat cell differentiation; small molecule metabolic process; triglyceride catabolic process; lipid metabolic process; negative regulation of protein kinase activity; cytokine production; cellular response to lithium ion; white fat cell differentiation; positive regulation of inflammatory response; negative regulation of transcription, DNA-dependent
FABP6lipid metabolic process; bile acid metabolic process; negative regulation of cell proliferation; bile acid and bile salt transport; small molecule metabolic process
FADDapoptotic process; innate immune response; necrotic cell death; cellular response to mechanical stimulus; extrinsic apoptotic signaling pathway; positive regulation of extrinsic apoptotic signaling pathway; positive regulation of type I interferon-mediated signaling pathway; defense response to virus; positive regulation of transcription from RNA polymerase II promoter; interspecies interaction between organisms; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptotic process; positive regulation of tumor necrosis factor production; positive regulation of interleukin-8 production; activation of pro-apoptotic gene products; induction of apoptosis via death domain receptors; induction of apoptosis by extracellular signals; signal transduction; activation of cysteine-type endopeptidase activity involved in apoptotic process
FAF2response to unfolded protein
FAHsmall molecule metabolic process; cellular nitrogen compound metabolic process; aromatic amino acid family metabolic process; tyrosine catabolic process; L-phenylalanine catabolic process; arginine catabolic process
FAM102B-
FAM104B-
FAM107B-
FAM109Aretrograde transport, endosome to Golgi; endosome organization; receptor recycling
FAM110A-
FAM110B-
FAM110C-
FAM111A-
FAM111B-
FAM114A1-
FAM117B-
FAM118B-
FAM120A-
FAM120AOS-
FAM120Bregulation of transcription, DNA-dependent; cell differentiation
FAM120C-
FAM122B-
FAM122C-
FAM124A-
FAM124B-
FAM126Asignal transduction
FAM129Apositive regulation of translation; response to endoplasmic reticulum stress; response to stress; positive regulation of protein phosphorylation; negative regulation of protein phosphorylation
FAM129Bnegative regulation of apoptotic process
FAM131A-
FAM131B-
FAM134Bsensory perception of pain
FAM134C-
FAM135A-
FAM135B-
FAM13Asmall GTPase mediated signal transduction; signal transduction; regulation of small GTPase mediated signal transduction
FAM13Bsignal transduction; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
FAM13C-
FAM149A-
FAM151A-
FAM155A-
FAM160A2protein transport; lysosome organization; endosome organization; endosome to lysosome transport; early endosome to late endosome transport
FAM160B1-
FAM161Aresponse to stimulus; visual perception
FAM161B-
FAM162B-
FAM163A-
FAM166A-
FAM167A-
FAM167B-
FAM170A-
FAM171A1-
FAM171B-
FAM172A-
FAM174A-
FAM175B-
FAM179B-
FAM180A-
FAM181A-
FAM184A-
FAM186B-
FAM188Aapoptotic process
FAM189B-
FAM193A-
FAM196A-
FAM198B-
FAM199X-
FAM19A3-
FAM19A4-
FAM208A-
FAM208B-
FAM209B-
FAM20A-
FAM210A-
FAM213Aregulation of osteoclast differentiation; oxidation-reduction process
FAM217A-
FAM217B-
FAM219B-
FAM228A-
FAM229B-
FAM234A-
FAM234B-
FAM3Binsulin secretion; apoptotic process
FAM43A-
FAM45A-
FAM46A-
FAM46C-
FAM46D-
FAM47A-
FAM49A-
FAM49B-
FAM50Aspermatogenesis
FAM53A-
FAM53B-
FAM57B-
FAM63A-
FAM63B-
FAM65A-
FAM65C-
FAM71A-
FAM71B-
FAM71C-
FAM71F1-
FAM73A-
FAM73B-
FAM78A-
FAM83A-
FAM83B-
FAM83E-
FAM83F-
FAM83G-
FAM83Hbiomineral tissue development
FAM84A-
FAM84B-
FAM8A1-
FAM91A1-
FAN1nucleotide-excision repair, DNA incision; nucleotide-excision repair; DNA repair; double-strand break repair via homologous recombination
FANCAfemale gonad development; DNA repair; protein complex assembly; male meiosis; regulation of cell proliferation; male gonad development
FANCBDNA repair
FANCCremoval of superoxide radicals; germ cell development; protein complex assembly; nucleotide-excision repair; DNA repair; myeloid cell homeostasis
FANCD2cell cycle; response to gamma radiation; gamete generation; synapsis; DNA repair
FANCIcell cycle; DNA repair
FANCLprotein ubiquitination; DNA repair
FANCMresolution of meiotic recombination intermediates; DNA repair; replication fork processing
FAPendothelial cell migration; regulation of fibrinolysis; negative regulation of extracellular matrix disassembly; metabolic process; proteolysis
FAR1cellular lipid metabolic process; small molecule metabolic process; ether lipid biosynthetic process; lipid biosynthetic process; wax biosynthetic process
FARP1negative regulation of phosphatase activity; regulation of Rho protein signal transduction
FARP2axon guidance; neuron remodeling; Rac protein signal transduction; regulation of Rho protein signal transduction
FARS2tRNA processing; tRNA aminoacylation for protein translation; phenylalanyl-tRNA aminoacylation; gene expression; tRNA aminoacylation
FARSAtRNA aminoacylation for protein translation; phenylalanyl-tRNA aminoacylation; gene expression
FASNvitamin metabolic process; small molecule metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; positive regulation of cellular metabolic process; triglyceride biosynthetic process; water-soluble vitamin metabolic process; fatty acid biosynthetic process; fatty acid metabolic process; energy reserve metabolic process; pantothenate metabolic process
FASTKregulation of RNA splicing; protein phosphorylation; apoptotic process; induction of apoptosis by extracellular signals
FASTKD1cellular respiration
FASTKD2cellular respiration
FASTKD5cellular respiration
FAT2cell adhesion; homophilic cell adhesion; epithelial cell migration
FAT4homophilic cell adhesion; cell adhesion
FATE1-
FAXDC2-
FBLN1embryo implantation; extracellular matrix organization; interspecies interaction between organisms
FBLN5cell adhesion; cell-matrix adhesion; extracellular matrix organization; regulation of removal of superoxide radicals; elastic fiber assembly; protein localization at cell surface
FBLN7cell adhesion
FBN1skeletal system development; heart development; negative regulation of BMP signaling pathway by extracellular sequestering of BMP; negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta
FBN2anatomical structure morphogenesis; bone trabecula formation; positive regulation of osteoblast differentiation; negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta; positive regulation of bone mineralization; embryonic limb morphogenesis
FBN3-
FBXL13-
FBXL16-
FBXL17-
FBXL18-
FBXL2proteolysis; protein modification process; protein ubiquitination; interspecies interaction between organisms
FBXL3SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; rhythmic process; regulation of circadian rhythm; protein ubiquitination
FBXO11protein ubiquitination; peptidyl-arginine N-methylation; sensory perception of sound; ubiquitin-dependent protein catabolic process; protein modification process
FBXO16-
FBXO18-
FBXO22positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process; protein polyubiquitination; protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; nucleocytoplasmic transport; cellular response to starvation; regulation of myotube differentiation
FBXO24protein ubiquitination
FBXO3proteolysis; protein ubiquitination
FBXO30-
FBXO31response to DNA damage stimulus; cell cycle; cyclin catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; mitotic cell cycle G1/S transition DNA damage checkpoint
FBXO32muscle atrophy
FBXO33-
FBXO38-
FBXO40muscle cell differentiation
FBXO42-
FBXO43meiosis
FBXO44protein catabolic process
FBXO47-
FBXO48-
FBXO5regulation of transcription involved in G1/S phase of mitotic cell cycle; M phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; mitotic cell cycle; inhibition of mitotic anaphase-promoting complex activity; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; cell division; spindle assembly; microtubule polymerization; regulation of meiosis; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; vesicle organization; regulation of mitotic cell cycle; mitotic metaphase/anaphase transition; spindle assembly involved in female meiosis I; oocyte maturation; mitotic metaphase
FBXO7ubiquitin-dependent protein catabolic process; cell death; protein ubiquitination; regulation of protein stability
FBXO8regulation of ARF protein signal transduction; ubiquitin-dependent protein catabolic process
FBXW12-
FBXW2protein modification process; proteolysis; protein ubiquitination
FBXW5protein ubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; centrosome duplication
FBXW7positive regulation of epidermal growth factor-activated receptor activity; negative regulation of triglyceride biosynthetic process; regulation of lipid storage; protein ubiquitination; sister chromatid cohesion; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of DNA endoreduplication; regulation of protein localization; cellular response to UV; interspecies interaction between organisms; response to DNA damage stimulus; vasculature development; negative regulation of Notch signaling pathway; protein stabilization; lipid homeostasis; positive regulation of ERK1 and ERK2 cascade; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of hepatocyte proliferation; negative regulation of SREBP-mediated signaling pathway
FBXW8labyrinthine layer blood vessel development; spongiotrophoblast layer development
FCAMR-
FCARimmune response
FCER1Apositive regulation of mast cell degranulation; positive regulation of type I hypersensitivity; serotonin secretion; cell surface receptor signaling pathway; activation of JUN kinase activity; leukotriene biosynthetic process; positive regulation of interleukin-3 biosynthetic process; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of calcium-mediated signaling
FCGBP-
FCGR2A-
FCGR2Bimmune response; signal transduction; interspecies interaction between organisms; regulation of immune response
FCGRTimmune response; antigen processing and presentation; female pregnancy
FCHO1-
FCN3signal transduction; complement activation, lectin pathway
FCRL3-
FCRL4-
FCRL5-
FCRLAcell differentiation
FCRLB-
FDCSP-
FDFT1cholesterol biosynthetic process; farnesyl diphosphate metabolic process; small molecule metabolic process; cellular lipid metabolic process; isoprenoid biosynthetic process; steroid biosynthetic process
FDPScholesterol biosynthetic process; isoprenoid biosynthetic process; small molecule metabolic process; interspecies interaction between organisms
FDX1regulation of catalytic activity; cellular response to leptin stimulus; positive regulation of oxidoreductase activity; NADPH oxidation; cellular response to organic cyclic compound; response to gonadotropin stimulus; adrenal gland development; electron transport chain; transport; generation of precursor metabolites and energy; cellular response to epinephrine stimulus
FDX1Ltransport; electron transport chain
FDXRelectron transport chain; cholesterol metabolic process; transport; oxidation-reduction process; NADPH oxidation; steroid biosynthetic process; generation of precursor metabolites and energy
FECHporphyrin-containing compound metabolic process; protoporphyrinogen IX metabolic process; small molecule metabolic process; response to light stimulus; heme biosynthetic process; generation of precursor metabolites and energy
FEM1Bregulation of DNA damage checkpoint; epithelial cell maturation involved in prostate gland development; branching involved in prostate gland morphogenesis; regulation of ubiquitin-protein ligase activity; induction of apoptosis; protein ubiquitination; regulation of apoptotic process
FEM1C-
FERregulation of lamellipodium assembly; positive regulation of cell proliferation; positive regulation of NF-kappaB transcription factor activity; platelet-derived growth factor receptor signaling pathway; protein autophosphorylation; regulation of epidermal growth factor receptor signaling pathway; intracellular signal transduction; negative regulation of mast cell activation involved in immune response; positive regulation of actin filament polymerization; microtubule cytoskeleton organization; protein phosphorylation; chemotaxis; cell adhesion; positive regulation of cell migration; peptidyl-tyrosine phosphorylation
FER1L6-
FERMT1establishment of epithelial cell polarity; keratinocyte migration; keratinocyte proliferation; cell adhesion
FERMT2cell adhesion; regulation of cell shape; cell junction assembly; actin cytoskeleton organization
FETUB-
FEZF1olfactory bulb development; negative regulation of transcription from RNA polymerase II promoter; neuron migration; multicellular organismal development; nervous system development; axon guidance; negative regulation of cell proliferation; telencephalon development; forebrain anterior/posterior pattern specification; cell differentiation; positive regulation of neuron differentiation; positive regulation of transcription, DNA-dependent
FEZF2dendrite development; positive regulation of transcription, DNA-dependent; positive regulation of neuron differentiation; cell differentiation; forebrain anterior/posterior pattern specification; dentate gyrus development; telencephalon development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; locomotory behavior; multicellular organismal development; nervous system development; axon guidance; axonal fasciculation
FFAR2G-protein coupled receptor signaling pathway
FFAR4-
FGAblood coagulation; response to calcium ion; protein polymerization; platelet degranulation; signal transduction; platelet activation
FGD1apoptotic process; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; filopodium assembly; regulation of Cdc42 GTPase activity; regulation of Rho protein signal transduction; actin cytoskeleton organization; organ morphogenesis; induction of apoptosis by extracellular signals; regulation of cell shape; multicellular organismal development; small GTPase mediated signal transduction; signal transduction; cytoskeleton organization
FGD3actin cytoskeleton organization; small GTPase mediated signal transduction; regulation of cell shape; cytoskeleton organization; apoptotic process; induction of apoptosis by extracellular signals; regulation of Rho protein signal transduction; nerve growth factor receptor signaling pathway; filopodium assembly; regulation of Cdc42 GTPase activity; regulation of small GTPase mediated signal transduction
FGD6actin cytoskeleton organization; filopodium assembly; regulation of Cdc42 GTPase activity; regulation of Rho protein signal transduction; regulation of cell shape; cytoskeleton organization
FGF13MAPK cascade; positive regulation of protein phosphorylation; nervous system development; cell-cell signaling; signal transduction
FGF17positive regulation of cell proliferation; fibroblast growth factor receptor signaling pathway; signal transduction; cell-cell signaling; multicellular organismal development; nervous system development; insulin receptor signaling pathway
FGF18angiogenesis; positive regulation of ERK1 and ERK2 cascade; positive regulation of chondrocyte differentiation; positive regulation of vascular endothelial growth factor receptor signaling pathway; lung development; anatomical structure morphogenesis; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of cell proliferation; cell-cell signaling; signal transduction; chondrocyte development; endochondral ossification; intramembranous ossification; ossification
FGF3positive regulation of cell division; negative regulation of cardiac muscle tissue development; semicircular canal morphogenesis; thymus development; tail morphogenesis; cell differentiation; otic vesicle formation; insulin receptor signaling pathway; positive regulation of cell proliferation; multicellular organismal development; cell-cell signaling; signal transduction; fibroblast growth factor receptor signaling pathway; organ induction; anatomical structure morphogenesis
FGF4positive regulation of ERK1 and ERK2 cascade; chondroblast differentiation; apoptosis involved in morphogenesis; cranial suture morphogenesis; positive regulation of cell division; positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; embryonic hindlimb morphogenesis; stem cell maintenance; positive regulation of gene expression; mesenchymal cell proliferation; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; cartilage condensation; signal transduction; cell-cell signaling; multicellular organismal development; positive regulation of cell proliferation; odontogenesis of dentin-containing tooth
FGF5fibroblast growth factor receptor signaling pathway; positive regulation of cell division; signal transduction involved in regulation of gene expression; glial cell differentiation; insulin receptor signaling pathway; positive regulation of cell proliferation; cell proliferation; nervous system development; cell-cell signaling
FGF7surfactant homeostasis; positive regulation of epithelial cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive chemotaxis; positive regulation of keratinocyte migration; positive regulation of cell division; branching involved in salivary gland morphogenesis; positive regulation of epithelial cell proliferation involved in lung morphogenesis; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; secretion by lung epithelial cell involved in lung growth; protein localization at cell surface; ovarian follicle development; phosphatidylcholine biosynthetic process; signal transduction; positive regulation of cell proliferation; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; epidermis development; phospholipid biosynthetic process; response to wounding; mesenchymal cell proliferation; positive regulation of keratinocyte proliferation; lung development; hair follicle morphogenesis; actin cytos
FGF8mesonephros development; dopaminergic neuron differentiation; neuroepithelial cell differentiation; bone development; negative regulation of cardiac muscle tissue development; positive regulation of cell division; anatomical structure morphogenesis; fibroblast growth factor receptor signaling pathway; gonad development; insulin receptor signaling pathway; positive regulation of cell proliferation; gastrulation; multicellular organismal development; outflow tract septum morphogenesis; metanephros development; odontogenesis
FGF9inner ear morphogenesis; positive regulation of MAPK cascade; positive regulation of smoothened signaling pathway; regulation of timing of cell differentiation; embryonic digestive tract development; embryonic skeletal system development; positive regulation of epithelial cell proliferation; positive regulation of cell division; positive regulation of cardiac muscle cell proliferation; positive regulation of canonical Wnt receptor signaling pathway; lung-associated mesenchyme development; embryonic limb morphogenesis; angiogenesis; osteoblast differentiation; positive regulation of mesenchymal cell proliferation; chondrocyte differentiation; protein import into nucleus; signal transduction; cell-cell signaling; positive regulation of vascular endothelial growth factor receptor signaling pathway; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; male gonad development; positive regulation of gene expression; negative regulation of Wnt receptor signaling pathway; male sex
FGFBP3positive regulation of vascular permeability; positive regulation of fibroblast growth factor receptor signaling pathway
FGFR1positive regulation of phospholipase C activity; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of cell proliferation; axon guidance; protein phosphorylation; regulation of transcription, DNA-dependent; neuron migration; skeletal system development; MAPK cascade; positive regulation of phospholipase activity; cell migration; peptidyl-tyrosine phosphorylation; chordate embryonic development; positive regulation of MAP kinase activity; positive regulation of MAPK cascade; regulation of cell differentiation; positive regulation of neuron differentiation; protein autophosphorylation; phosphatidylinositol-mediated signaling; skeletal system morphogenesis; positive regulation of phosphatidylinositol 3-kinase cascade
FGFR1OP2response to wounding
FGFR2lung development; regulation of osteoblast proliferation; bone mineralization; positive regulation of Wnt receptor signaling pathway; gland morphogenesis; pyramidal neuron development; ventricular zone neuroblast division; orbitofrontal cortex development; peptidyl-tyrosine phosphorylation; morphogenesis of embryonic epithelium; epithelial cell differentiation; midbrain development; otic vesicle formation; hair follicle morphogenesis; lacrimal gland development; organ growth; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; multicellular organism growth; fibroblast growth factor receptor signaling pathway involved in hemopoiesis; axonogenesis; negative regulation of transcription from RNA polymerase II promoter; angiogenesis; ureteric bud development; in utero embryonic development; positive regulation of mesenchymal cell proliferation; outflow tract septum morphogenesis; membranous septum morphogenesis; apoptotic process; cell-cell signa
FGFR3MAPK cascade; skeletal system development; endochondral ossification; chondrocyte differentiation; positive regulation of phosphatidylinositol 3-kinase activity; bone maturation; positive regulation of ERK1 and ERK2 cascade; bone morphogenesis; negative regulation of developmental growth; protein autophosphorylation; endochondral bone growth; positive regulation of MAPK cascade; regulation of apoptotic process; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of tyrosine phosphorylation of Stat1 protein; chondrocyte proliferation; peptidyl-tyrosine phosphorylation; positive regulation of phospholipase activity; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; positive regulation of cell proliferation; JAK-STAT cascade
FGFR4positive regulation of cell proliferation; insulin receptor signaling pathway; fibroblast growth factor receptor signaling pathway; regulation of extracellular matrix disassembly; cell migration; peptidyl-tyrosine phosphorylation; regulation of lipid metabolic process; positive regulation of proteolysis; protein autophosphorylation; positive regulation of metalloenzyme activity; phosphate ion homeostasis; positive regulation of ERK1 and ERK2 cascade; regulation of bile acid biosynthetic process; regulation of cholesterol homeostasis; positive regulation of DNA biosynthetic process; glucose homeostasis
FGFRL1fibroblast growth factor receptor signaling pathway; heart valve morphogenesis; negative regulation of cell proliferation; protein phosphorylation; skeletal system development; regulation of cell growth; diaphragm development; ventricular septum morphogenesis
FGGplatelet activation; response to calcium ion; protein polymerization; blood coagulation; signal transduction; platelet degranulation
FGGYcell death; neuron homeostasis; carbohydrate metabolic process
FGL1signal transduction
FGL2signal transduction
FGRpositive regulation of phosphatidylinositol 3-kinase activity; defense response to Gram-positive bacterium; regulation of phagocytosis; positive regulation of cytokine secretion; protein autophosphorylation; regulation of protein kinase activity; regulation of innate immune response; positive regulation of mast cell degranulation; peptidyl-tyrosine phosphorylation; immune response-regulating cell surface receptor signaling pathway; positive regulation of phosphatidylinositol 3-kinase cascade; response to virus; regulation of cell shape; blood coagulation; integrin-mediated signaling pathway; protein phosphorylation; positive regulation of cell migration
FHtricarboxylic acid cycle; fumarate metabolic process; malate metabolic process; small molecule metabolic process; homeostasis of number of cells within a tissue
FHL1multicellular organismal development; muscle organ development; organ morphogenesis; negative regulation of G2/M transition of mitotic cell cycle; cell differentiation; negative regulation of cell growth; negative regulation of G1/S transition of mitotic cell cycle
FHL2heart trabecula formation; ventricular cardiac muscle cell development; atrial cardiac muscle cell development; positive regulation of transcription, DNA-dependent; small molecule metabolic process; negative regulation of apoptotic process; androgen receptor signaling pathway; response to hormone stimulus; osteoblast differentiation; negative regulation of transcription from RNA polymerase II promoter; cellular lipid metabolic process
FHL3muscle organ development; actin cytoskeleton organization
FHOD1positive regulation of transcription from RNA polymerase II promoter; actin cytoskeleton organization; cellular component organization; positive regulation of stress fiber assembly
FHOD3cellular component organization; actin cytoskeleton organization
FIBIN-
FIBPfibroblast growth factor receptor signaling pathway
FIG4locomotory behavior; phosphatidylinositol metabolic process; pigmentation; cell death; positive regulation of neuron projection development; neuron development; vacuole organization
FIGFpositive regulation of interleukin-6 production; response to interleukin-1; positive regulation of mast cell chemotaxis; positive regulation of cell division; induction of positive chemotaxis; positive chemotaxis; vascular endothelial growth factor receptor signaling pathway; regulation of vascular endothelial growth factor receptor signaling pathway; cell differentiation; positive regulation of cell proliferation; blood coagulation; multicellular organismal development; platelet degranulation; response to hypoxia; platelet activation; angiogenesis
FIGNlocomotory behavior
FIGNL1regulation of cell cycle; ATP metabolic process; osteoblast proliferation; osteoblast differentiation; negative regulation of apoptotic process
FILIP1-
FILIP1L-
FIP1L1mRNA processing
FIS1positive regulation of intrinsic apoptotic signaling pathway; reduction of endoplasmic reticulum calcium ion concentration; peroxisome fission; elevation of cytosolic calcium ion concentration; apoptotic process; mitochondrial fission; release of cytochrome c from mitochondria; elevation of mitochondrial calcium ion concentration; mitochondrial fragmentation involved in apoptosis; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; calcium-mediated signaling using intracellular calcium source; mitochondrion degradation
FITM2cellular triglyceride homeostasis; lipid particle organization; regulation of triglyceride biosynthetic process; regulation of cell morphogenesis; positive regulation of sequestering of triglyceride; cytoskeleton organization
FIZ1regulation of transcription, DNA-dependent
FKBP11protein peptidyl-prolyl isomerization; protein folding; peptidyl-proline modification
FKBP5peptidyl-proline modification; protein peptidyl-prolyl isomerization; protein folding
FKBP8interspecies interaction between organisms; intracellular signal transduction; peptidyl-proline modification; apoptotic process; protein folding; protein peptidyl-prolyl isomerization
FLAD1vitamin metabolic process; FAD biosynthetic process; small molecule metabolic process; Mo-molybdopterin cofactor biosynthetic process; water-soluble vitamin metabolic process; riboflavin metabolic process
FLCNregulation of protein phosphorylation
FLGkeratinocyte differentiation; multicellular organismal development
FLG2-
FLIIregulation of transcription, DNA-dependent; muscle contraction; multicellular organismal development
FLNApositive regulation of I-kappaB kinase/NF-kappaB cascade; receptor clustering; protein localization at cell surface; positive regulation of transcription factor import into nucleus; negative regulation of protein catabolic process; negative regulation of sequence-specific DNA binding transcription factor activity; early endosome to late endosome transport; establishment of protein localization; protein stabilization; cytoplasmic sequestering of protein; actin crosslink formation; spindle assembly involved in mitosis; platelet degranulation; inhibition of adenylate cyclase activity by dopamine receptor signaling pathway; blood coagulation; cell junction assembly; actin cytoskeleton reorganization; platelet activation
FLNBcell differentiation; actin cytoskeleton organization; cytokine-mediated signaling pathway; muscle organ development; multicellular organismal development; signal transduction; cytoskeletal anchoring at plasma membrane
FLNCmuscle fiber development; cell junction assembly
FLOT2epidermis development; cell adhesion
FLRT1cell adhesion
FLRT2cell adhesion
FLRT3cell adhesion
FLT1vascular endothelial growth factor receptor signaling pathway; blood vessel morphogenesis; embryonic morphogenesis; positive regulation of smooth muscle cell proliferation; positive regulation of angiogenesis; response to hypoxia; protein autophosphorylation; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of MAPK cascade; positive regulation of MAP kinase activity; vascular endothelial growth factor signaling pathway; cellular response to vascular endothelial growth factor stimulus; positive regulation of vascular endothelial growth factor receptor signaling pathway; intracellular receptor mediated signaling pathway; positive regulation of cell migration; cell differentiation; peptidyl-tyrosine phosphorylation; positive regulation of phosphatidylinositol 3-kinase cascade; activation of MAPKK activity; monocyte chemotaxis; chemotaxis; regulation of smooth muscle contraction; transmembrane receptor protein tyrosine kinase signaling pathway; cell migration; positive regulation
FLT3positive regulation of phosphatidylinositol 3-kinase cascade; pro-T cell differentiation; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; hemopoiesis; lymphocyte differentiation; vascular endothelial growth factor signaling pathway; positive regulation of tyrosine phosphorylation of STAT protein; regulation of apoptotic process; positive regulation of MAP kinase activity; negative regulation of cell proliferation; positive regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; pro-B cell differentiation; myeloid progenitor cell differentiation; cellular response to cytokine stimulus; protein autophosphorylation; negative regulation of B cell differentiation; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of MAPK cascade
FLT4positive regulation of ERK1 and ERK2 cascade; blood vessel morphogenesis; positive regulation of protein kinase C signaling cascade; positive regulation of protein phosphorylation; positive regulation of endothelial cell proliferation; vasculature development; lymphangiogenesis; sprouting angiogenesis; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell proliferation; positive regulation vascular endothelial growth factor production; positive regulation of endothelial cell migration; peptidyl-tyrosine phosphorylation; cellular response to vascular endothelial growth factor stimulus; vascular endothelial growth factor signaling pathway; negative regulation of apoptotic process; positive regulation of MAPK cascade; positive regulation of JNK cascade; protein autophosphorylation; vascular endothelial growth factor receptor signaling pathway; regulation of blood vessel remodeling
FLVCR2heme transport; transmembrane transport
FMN2polar body extrusion after meiotic divisions; establishment of meiotic spindle localization; oogenesis; meiotic metaphase I; multicellular organismal development; cellular component organization; meiotic chromosome movement towards spindle pole; actin cytoskeleton organization; intracellular signal transduction
FMNL1cortical actin cytoskeleton organization; substrate-dependent cell migration; regulation of cell shape; cellular process; cellular component organization
FMNL3actin cytoskeleton organization; cell migration; cellular component organization; regulation of cell shape; cytoskeleton organization
FMO1organic acid metabolic process; xenobiotic metabolic process; response to osmotic stress; toxin metabolic process; response to lipopolysaccharide; small molecule metabolic process; NADPH oxidation
FMO2organic acid metabolic process; NADP metabolic process; xenobiotic metabolic process; toxin metabolic process; drug metabolic process; small molecule metabolic process; NADPH oxidation; oxygen metabolic process
FMO3drug metabolic process; small molecule metabolic process; xenobiotic metabolic process
FMO5oxidation-reduction process
FMR1central nervous system development; mRNA transport; negative regulation of translational initiation; transport
FMR1NB-
FN1acute-phase response; leukocyte migration; substrate adhesion-dependent cell spreading; platelet activation; peptide cross-linking; cell migration; response to wounding; blood coagulation; cell adhesion; regulation of cell shape; platelet degranulation; angiogenesis
FN3KRP-
FNBP4-
FNDC3Afertilization; spermatid development; cell-cell adhesion; Sertoli cell development
FNDC9-
FNIP1regulation of protein phosphorylation
FNTApositive regulation of deacetylase activity; positive regulation of tubulin deacetylation; protein geranylgeranylation; protein farnesylation; transforming growth factor beta receptor signaling pathway; cellular component disassembly involved in apoptosis; apoptotic process
FOCAD-
FOSSMAD protein signal transduction; cellular response to calcium ion; response to cAMP; response to corticosterone stimulus; stress-activated MAPK cascade; regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; innate immune response; response to drug; TRIF-dependent toll-like receptor signaling pathway; cellular response to reactive oxygen species; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; response to cytokine stimulus; cellular response to hormone stimulus; response to progesterone stimulus; response to lipopolysaccharide; cellular response to extracellular stimulus; sleep; response to organic cyclic compound; response to mechanical stimulus; inflammatory response; transforming growth factor beta receptor signaling pathway; nervous system development; f
FOSL1cellular response to extracellular stimulus; cellular defense response; female pregnancy; learning; positive regulation of cell proliferation; negative regulation of cell proliferation; positive regulation of cell cycle; positive regulation of apoptotic process; response to hydrogen peroxide; response to drug; response to cytokine stimulus; response to progesterone stimulus; response to organic cyclic compound; positive regulation of transcription from RNA polymerase II promoter during mitosis; response to corticosterone stimulus; response to cAMP; chemotaxis; response to gravity; response to virus; response to mechanical stimulus; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
FOSL2positive regulation of fibroblast proliferation; cell death; regulation of transcription from RNA polymerase II promoter
FOXA3chromatin modification; embryo development; spermatogenesis; cellular response to starvation; positive regulation of hepatocyte differentiation; lung epithelial cell differentiation; epithelial tube branching involved in lung morphogenesis; regulation of sequence-specific DNA binding transcription factor activity; neuron fate specification; positive regulation of transcription from RNA polymerase II promoter; response to nutrient levels; endocrine pancreas development; cell differentiation; neural plate anterior/posterior regionalization; negative regulation of cell proliferation; brain development; regulation of transcription, DNA-dependent; cellular glucose homeostasis
FOXF2establishment of planar polarity of embryonic epithelium; extracellular matrix organization; tissue development; embryo development; pattern specification process; epithelial to mesenchymal transition; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; embryonic digestive tract development; genitalia development; regulation of sequence-specific DNA binding transcription factor activity; palate development
FOXG1multicellular organismal development; regulation of mitotic cell cycle; brain development; embryo development ending in birth or egg hatching; tissue development; dorsal/ventral pattern formation; axon midline choice point recognition; central nervous system neuron development; regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of cell cycle; negative regulation of neuron differentiation; nose development; inner ear morphogenesis; nonmotile primary cilium assembly; hindbrain development; positive regulation of neuroblast proliferation
FOXJ3pattern specification process; organ development; embryo development; positive regulation of transcription, DNA-dependent; tissue development; regulation of sequence-specific DNA binding transcription factor activity
FOXK1negative regulation of cell growth; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of sequence-specific DNA binding transcription factor activity; cell differentiation; tissue development; embryo development; muscle organ development; pattern specification process; regulation of transcription from RNA polymerase II promoter
FOXL2NB-
FOXM1positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; regulation of cell proliferation; negative regulation of stress-activated MAPK cascade; tissue development; embryo development; vasculogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of Ras protein signal transduction; positive regulation of double-strand break repair; regulation of reactive oxygen species metabolic process; negative regulation of cell aging; regulation of cell cycle arrest; regulation of sequence-specific DNA binding transcription factor activity; pattern specification process; cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; DNA repair; liver development; regulation of cell growth; negative regulation of transcription from RNA polymerase I
FOXN1keratinocyte differentiation; regulation of sequence-specific DNA binding transcription factor activity; epithelial cell proliferation; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; defense response; pattern specification process; epidermis development; embryo development; organ morphogenesis; thymus development
FOXP1in utero embryonic development; sarcomere organization; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; smooth muscle tissue development; regulation of sequence-specific DNA binding transcription factor activity; cardiac muscle cell differentiation; regulation of cardiac muscle cell proliferation; positive regulation of epithelial cell proliferation involved in lung morphogenesis; positive regulation of cardiac muscle cell differentiation; lung development; heart development; skeletal muscle tissue development; pattern specification process; pre-B cell differentiation; positive regulation of immunoglobulin production; positive regulation of mesenchymal cell proliferation; immunoglobulin V(D)J recombination; motor axon guidance; embryo development; ventral spinal cord development
FOXP2growth; skeletal muscle tissue development; positive regulation of epithelial cell proliferation involved in lung morphogenesis; righting reflex; regulation of sequence-specific DNA binding transcription factor activity; smooth muscle tissue development; lung alveolus development; negative regulation of transcription, DNA-dependent; camera-type eye development; vocal learning; caudate nucleus development; putamen development; cerebral cortex development; positive regulation of mesenchymal cell proliferation; pattern specification process; embryo development; post-embryonic development; cerebellum development
FOXP3growth; positive regulation of histone acetylation; negative regulation of histone acetylation; negative regulation of tumor necrosis factor production; negative regulation of cytokine biosynthetic process; T cell activation; negative regulation of T cell proliferation; vocal learning; camera-type eye development; T cell homeostasis; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of interferon-gamma biosynthetic process; negative regulation of T cell cytokine production; embryo development; response to virus; negative regulation of cell proliferation; skeletal muscle tissue development; pattern specification process; regulation of transcription, DNA-dependent; chromatin remodeling; positive regulation of peripheral T cell tolerance induction; post-embryonic development; negative regulation of chronic inflammatory response; positive regulation of T cell anergy; regulation of immunoglobulin production; tolerance induction to self antigen; T cell mediated
FOXP4pattern specification process; regulation of sequence-specific DNA binding transcription factor activity; embryonic foregut morphogenesis; tissue development; heart development
FOXQ1positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; DNA fragmentation involved in apoptotic nuclear change; pattern specification process; regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; hair follicle morphogenesis; embryo development
FOXR1pattern specification process; embryo development; tissue development; organ development; regulation of sequence-specific DNA binding transcription factor activity
FOXRED2ER-associated protein catabolic process
FOXS1negative regulation of transcription, DNA-dependent; ventricular cardiac muscle tissue morphogenesis; cardiac muscle cell proliferation; ossification; blood vessel development; patterning of blood vessels; vasculogenesis; metanephros development; ureteric bud development; somitogenesis; lymphangiogenesis; blood vessel remodeling; regulation of transcription, DNA-dependent; anti-apoptosis; Notch signaling pathway; multicellular organismal development; insulin receptor signaling pathway; collagen fibril organization; neural crest cell fate commitment; neuromuscular process controlling balance; regulation of blood vessel size; artery morphogenesis; embryonic viscerocranium morphogenesis; paraxial mesodermal cell fate commitment; vascular endothelial growth factor receptor signaling pathway; regulation of organ growth; positive regulation of transcription from RNA polymerase II promoter; negative regulation of sequence-specific DNA binding transcription factor activity; camera-type eye development; positive regul
FPGTfucose metabolic process
FPR1activation of MAPK activity; cellular component movement; chemotaxis; signal transduction; nitric oxide mediated signal transduction; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor signaling pathway
FPR2G-protein coupled receptor signaling pathway; cellular component movement; chemotaxis; inflammatory response; cell adhesion
FPR3cellular component movement; chemotaxis; signal transduction
FRA10AC1-
FREM2morphogenesis of an epithelium; cell communication; cell adhesion; homophilic cell adhesion; multicellular organismal development
FRKprotein phosphorylation; cell differentiation; negative regulation of cell proliferation
FRMD1-
FRMD4A-
FRMD5-
FRMD6-
FRMD7nervous system development; regulation of neuron projection development
FRMD8-
FRMPD1-
FRMPD2tight junction assembly
FRMPD4positive regulation of synapse structural plasticity
FRRS1electron transport chain; transport
FRRS1L-
FRS2insulin receptor signaling pathway; neuroblast proliferation; activation of phospholipase C activity; G-protein coupled receptor signaling pathway; activation of MAPK activity; fibroblast growth factor receptor signaling pathway; anterior/posterior axis specification, embryo; forebrain development; optic placode formation involved in camera-type eye formation; activation of MAPKK activity; nerve growth factor receptor signaling pathway; regulation of epithelial cell proliferation; gastrulation with mouth forming second; organ induction; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; transmembrane receptor protein tyrosine phosphatase signaling pathway; ventricular septum development
FRS3signal transduction; fibroblast growth factor receptor signaling pathway
FRYregulation of transcription, DNA-dependent
FRYLregulation of transcription, DNA-dependent
FSCBpeptidyl-serine phosphorylation
FSCN3-
FSD1cell cycle; cell division; mitosis
FSHRfollicle-stimulating hormone signaling pathway; G-protein coupled receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; spermatogenesis; female gamete generation; gonad development; male gonad development; female gonad development; regulation of chromosome organization; spermatogenesis, exchange of chromosomal proteins; transcytosis
FSIP1-
FSIP2-
FSThemopoietic progenitor cell differentiation; signal transduction; negative regulation of follicle-stimulating hormone secretion; positive regulation of hair follicle development; negative regulation of transcription from RNA polymerase II promoter; negative regulation of activin receptor signaling pathway
FSTL4-
FSTL5-
FTCDhistidine catabolic process; cytoskeleton organization; folic acid-containing compound metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process
FTMTpositive regulation of oxidoreductase activity; positive regulation of lyase activity; positive regulation of transferase activity; iron ion transport; cellular iron ion homeostasis; positive regulation of cell proliferation
FTOregulation of respiratory system process; DNA demethylation; oxidative demethylation; regulation of white fat cell proliferation; adipose tissue development; RNA repair; regulation of multicellular organism growth; oxidative single-stranded RNA demethylation; oxidative single-stranded DNA demethylation; temperature homeostasis; DNA dealkylation involved in DNA repair; regulation of lipid storage
FTSJ3RNA methylation; rRNA processing
FUBP3transcription, DNA-dependent; regulation of gene expression; positive regulation of transcription, DNA-dependent
FUCA1glycosaminoglycan catabolic process; fucose metabolic process; carbohydrate metabolic process
FUCA2carbohydrate metabolic process; fucose metabolic process
FUKmetabolic process
FURINpost-translational protein modification; positive regulation of membrane protein ectodomain proteolysis; regulation of endopeptidase activity; nerve growth factor receptor signaling pathway; signal peptide processing; proteolysis; Notch signaling pathway; cellular protein metabolic process; peptide biosynthetic process; regulation of protein catabolic process; secretion by cell; negative regulation of transforming growth factor beta1 production; negative regulation of nerve growth factor production; nerve growth factor production; negative regulation of low-density lipoprotein particle receptor catabolic process; nerve growth factor processing; positive regulation of transforming growth factor beta receptor signaling pathway; cell proliferation; protein processing; peptide hormone processing; peptidyl-glutamic acid carboxylation; viral assembly, maturation, egress, and release; positive regulation of cell migration; aging; transforming growth factor beta receptor signaling pathway
FUT1fucosylation; L-fucose catabolic process; protein glycosylation; carbohydrate metabolic process
FUT2carbohydrate metabolic process; protein glycosylation; fucosylation; L-fucose catabolic process
FUT8N-glycan processing; cellular protein metabolic process; post-translational protein modification; receptor metabolic process; L-fucose catabolic process; N-glycan fucosylation; protein glycosylation in Golgi; protein N-linked glycosylation via asparagine; cell migration; oligosaccharide biosynthetic process; respiratory gaseous exchange; integrin-mediated signaling pathway; transforming growth factor beta receptor signaling pathway; protein N-linked glycosylation; in utero embryonic development
FXR1cell differentiation; negative regulation of translation; muscle organ development; multicellular organismal development; apoptotic process
FXYD4ion transport
FXYD5negative regulation of calcium-dependent cell-cell adhesion; microvillus assembly; ion transport
FYCO1transport; plus-end-directed vesicle transport along microtubule
FYNblood coagulation; multicellular organismal development; axon guidance; leukocyte migration; T cell receptor signaling pathway; regulation of defense response to virus by virus; interspecies interaction between organisms; intracellular protein kinase cascade; protein phosphorylation; T cell costimulation; platelet activation; viral reproduction; feeding behavior; calcium ion transport; learning
FYTTD1mRNA export from nucleus; transport
FZD1canonical Wnt receptor signaling pathway involved in osteoblast differentiation; Wnt receptor signaling pathway, calcium modulating pathway; negative regulation of transcription, DNA-dependent; canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation; response to drug; autocrine signaling; lung alveolus development; positive regulation of sequence-specific DNA binding transcription factor activity; hard palate development; canonical Wnt receptor signaling pathway; regulation of osteoblast differentiation; embryo development; cellular response to vitamin D; cellular response to growth factor stimulus; cellular response to peptide hormone stimulus; negative regulation of canonical Wnt receptor signaling pathway; planar cell polarity pathway involved in neural tube closure; positive regulation of transcription, DNA-dependent; negative regulation of catenin import into nucleus; epithelial cell differentiation; negative regulation of BMP signaling pathway; neuron differentiation;
FZD10brain development; vasculature development; cellular response to retinoic acid; canonical Wnt receptor signaling pathway; positive regulation of JUN kinase activity; non-canonical Wnt receptor signaling pathway; negative regulation of Rho GTPase activity; regulation of actin cytoskeleton organization; positive regulation of Rac GTPase activity; neuron differentiation; embryo development; gonad development
FZD3neural tube closure; vasculature development; G-protein signaling, coupled to cGMP nucleotide second messenger; canonical Wnt receptor signaling pathway; multicellular organismal development; gonad development; facial nucleus development; neuron differentiation; cell proliferation in midbrain; inner ear morphogenesis; establishment of planar polarity; commissural neuron axon guidance
FZD4positive regulation of transcription, DNA-dependent; retinal blood vessel morphogenesis; blood vessel development; vasculogenesis; Wnt receptor signaling pathway, calcium modulating pathway; brain development; sensory perception of sound; embryo development; negative regulation of cell-substrate adhesion; Wnt receptor signaling pathway; neuron differentiation; regulation of vascular endothelial growth factor receptor signaling pathway; substrate adhesion-dependent cell spreading; extracellular matrix-cell signaling; progesterone secretion; positive regulation of sequence-specific DNA binding transcription factor activity; canonical Wnt receptor signaling pathway; retina vasculature morphogenesis in camera-type eye; cerebellum vasculature morphogenesis; cellular response to retinoic acid; locomotion involved in locomotory behavior
FZD5brain development; axonogenesis; multicellular organismal development; apoptotic process; angiogenesis; embryonic axis specification; Wnt receptor signaling pathway involved in dorsal/ventral axis specification; anterior/posterior axis specification, embryo; gonad development; Spemann organizer formation; neuron differentiation; embryonic camera-type eye development; post-embryonic camera-type eye development; positive regulation of interferon-gamma production; T cell differentiation in thymus; positive regulation of transcription from RNA polymerase II promoter; cellular response to molecule of bacterial origin; labyrinthine layer blood vessel development; canonical Wnt receptor signaling pathway
FZD6multicellular organismal development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of sequence-specific DNA binding transcription factor activity; inner ear morphogenesis; non-canonical Wnt receptor signaling pathway; cell proliferation in midbrain; gonad development; axonogenesis; G-protein signaling, coupled to cGMP nucleotide second messenger; neural tube closure; establishment of planar polarity; angiogenesis
FZD7negative regulation of cell-substrate adhesion; vasculature development; regulation of transcription, DNA-dependent; G-protein signaling, coupled to cGMP nucleotide second messenger; Wnt receptor signaling pathway, calcium modulating pathway; multicellular organismal development; axonogenesis; brain development; gonad development; cellular response to retinoic acid; mesenchymal to epithelial transition; canonical Wnt receptor signaling pathway; positive regulation of epithelial cell proliferation involved in wound healing; somatic stem cell division; positive regulation of JNK cascade; positive regulation of transcription, DNA-dependent; negative regulation of ectodermal cell fate specification; positive regulation of phosphorylation; non-canonical Wnt receptor signaling pathway; regulation of catenin import into nucleus; substrate adhesion-dependent cell spreading; T cell differentiation in thymus; neuron differentiation; stem cell maintenance; satellite cell maintenance involved in skeletal muscle regenerat
FZD9canonical Wnt receptor signaling pathway; vasculature development; nervous system development; neuroblast proliferation; gonad development; learning or memory; brain development; embryo development; B cell differentiation
FZR1anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; S phase of mitotic cell cycle; mitotic cell cycle; negative regulation of cell aging; protein K11-linked ubiquitination; lens fiber cell differentiation; DNA repair; activation of anaphase-promoting complex activity; mitosis; positive regulation of cell proliferation; cell division; positive regulation of protein catabolic process; regulation of meiosis; G2/M transition DNA damage checkpoint; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; phosphorylation; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
G2E3multicellular organismal development; protein modification process; blastocyst development; protein polyubiquitination; negative regulation of apoptotic process
G3BP2cytoplasmic sequestering of NF-kappaB; transport; regulation of small GTPase mediated signal transduction; mRNA transport; Ras protein signal transduction; small GTPase mediated signal transduction
G6PC3gluconeogenesis; carbohydrate metabolic process; transmembrane transport; glucose 6-phosphate metabolic process; glucose-6-phosphate transport; small molecule metabolic process; glucose transport; hexose transport; dephosphorylation
GAAlocomotory behavior; vacuolar sequestering; tissue development; glycogen catabolic process; tongue morphogenesis; muscle cell homeostasis; neuromuscular process controlling posture; neuromuscular process controlling balance; ventricular cardiac muscle tissue morphogenesis; cardiac muscle contraction; lysosome organization; glucose metabolic process; sucrose metabolic process; maltose metabolic process; regulation of the force of heart contraction; diaphragm contraction; heart morphogenesis; carbohydrate metabolic process; muscle organ development
GAB1epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; cell proliferation
GAB3-
GABARAPL1-
GABBR2G-protein coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; gamma-aminobutyric acid signaling pathway; synaptic transmission
GABPB1regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter
GABRA1transport; chloride transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; transmembrane transport
GABRA2transmembrane transport; ion transmembrane transport; synaptic transmission; gamma-aminobutyric acid signaling pathway; chloride transport; regulation of neurotransmitter levels; neurotransmitter transport
GABRA4transmembrane transport; ion transmembrane transport; synaptic transmission; chloride transport; transport; gamma-aminobutyric acid signaling pathway
GABRA6transport; chloride transport; signal transduction; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; transmembrane transport; synaptic transmission, GABAergic
GABRB1transmembrane transport; ion transmembrane transport; synaptic transmission; signal transduction; chloride transport; transport
GABRB2transmembrane transport; transport; chloride transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport
GABREgamma-aminobutyric acid signaling pathway; ion transport; transport
GABRG1synaptic transmission; gamma-aminobutyric acid signaling pathway; ion transport
GABRG2chloride transport; transmembrane transport; ion transmembrane transport; synaptic transmission; gamma-aminobutyric acid signaling pathway; transport
GABRPion transport
GABRR1transport; chloride transport; gamma-aminobutyric acid signaling pathway; synaptic transmission; ion transmembrane transport; transmembrane transport
GAD2response to drug; neurotransmitter biosynthetic process; carboxylic acid metabolic process; neurotransmitter secretion; synaptic transmission; glutamate decarboxylation to succinate
GADD45GIP1cell cycle; interspecies interaction between organisms
GADL1carboxylic acid metabolic process
GAKcell cycle
GAL3ST1sphingolipid metabolic process; myelination; small molecule metabolic process; biosynthetic process; spermatogenesis; glycosphingolipid metabolic process; protein N-linked glycosylation; galactosylceramide biosynthetic process
GAL3ST2biosynthetic process
GAL3ST4sulfur compound metabolic process; cell-cell signaling; proteoglycan biosynthetic process; biosynthetic process; glycoprotein metabolic process; oligosaccharide metabolic process
GALCcarbohydrate metabolic process; glycosphingolipid metabolic process; small molecule metabolic process; galactosylceramide catabolic process; sphingolipid metabolic process
GALK1carbohydrate phosphorylation; small molecule metabolic process; galactitol metabolic process; galactose catabolic process; galactose metabolic process; carbohydrate metabolic process
GALMhexose metabolic process; carbohydrate metabolic process
GALNS-
GALNT1O-glycan processing; post-translational protein modification; cellular protein metabolic process; protein O-linked glycosylation via threonine; protein O-linked glycosylation via serine; protein O-linked glycosylation
GALNT11carbohydrate metabolic process; O-glycan processing; post-translational protein modification; cellular protein metabolic process
GALNT12cellular protein metabolic process; post-translational protein modification; O-glycan processing
GALNT13O-glycan processing; post-translational protein modification; cellular protein metabolic process
GALNT14O-glycan processing; cellular protein metabolic process; carbohydrate metabolic process; post-translational protein modification
GALNT15-
GALNT16-
GALNT2cellular protein metabolic process; post-translational protein modification; protein O-linked glycosylation via threonine; protein O-linked glycosylation via serine; O-glycan processing; immunoglobulin biosynthetic process
GALNT3carbohydrate metabolic process; O-glycan processing; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine; post-translational protein modification; cellular protein metabolic process
GALNT5cellular protein metabolic process; post-translational protein modification; O-glycan processing; glycosaminoglycan biosynthetic process
GALNT6cellular protein metabolic process; post-translational protein modification; O-glycan processing; protein O-linked glycosylation
GALNT7post-translational protein modification; O-glycan processing; protein O-linked glycosylation; carbohydrate metabolic process; cellular protein metabolic process
GALNT8post-translational protein modification; cellular protein metabolic process; O-glycan processing
GALNT9cellular protein metabolic process; post-translational protein modification; O-glycan processing; protein O-linked glycosylation
GALNTL6-
GALR1digestion; neuropeptide signaling pathway; negative regulation of adenylate cyclase activity; activation of adenylate cyclase activity by G-protein signaling pathway
GALR2G-protein signaling, coupled to cAMP nucleotide second messenger; muscle contraction; cell surface receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; elevation of cytosolic calcium ion concentration; synaptic transmission; multicellular organismal development; digestion; learning or memory; feeding behavior; neuron projection development; inositol phosphate metabolic process; phosphatidylinositol metabolic process
GALR3learning or memory; negative regulation of adenylate cyclase activity; neuropeptide signaling pathway; synaptic transmission; feeding behavior
GAMTcreatine metabolic process; creatine biosynthetic process; muscle contraction; methylation; cellular nitrogen compound metabolic process; small molecule metabolic process
GANcell death
GANABprotein N-linked glycosylation via asparagine; carbohydrate metabolic process; protein folding; cellular protein metabolic process; post-translational protein modification
GANCcarbohydrate metabolic process
GAP43multicellular organismal development; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; nervous system development; response to wounding; cell differentiation; regulation of growth; regulation of filopodium assembly
GAPVD1endocytosis; signal transduction; regulation of small GTPase mediated signal transduction; regulation of protein transport
GARNL3regulation of small GTPase mediated signal transduction
GARTbiosynthetic process; 'de novo' IMP biosynthetic process; purine nucleotide biosynthetic process; purine base metabolic process; purine base biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; response to organic substance; response to inorganic substance; small molecule metabolic process; organ development; nucleobase-containing small molecule metabolic process
GAS2regulation of cell shape; apoptotic process; cellular component disassembly involved in apoptosis; cell cycle; cell cycle arrest
GAS2L2microtubule bundle formation; negative regulation of microtubule depolymerization; cell cycle arrest
GAS2L3cell cycle arrest
GAS7cell cycle arrest; multicellular organismal development; nervous system development; regulation of cell shape; actin filament polymerization; neuron differentiation; neuron projection morphogenesis; actin filament bundle assembly; regulation of transcription, DNA-dependent
GAS8negative regulation of cell proliferation; sperm motility
GATA1negative regulation of bone mineralization; dendritic cell differentiation; positive regulation of osteoblast proliferation; embryonic hemopoiesis; eosinophil fate commitment; negative regulation of apoptotic process; positive regulation of anti-apoptosis; positive regulation of transcription from RNA polymerase II promoter; erythrocyte development; positive regulation of peptidyl-tyrosine phosphorylation; Sertoli cell development; platelet aggregation; cellular response to cAMP; cellular response to follicle-stimulating hormone stimulus; transcriptional activation by promoter-enhancer looping; eosinophil differentiation; basophil differentiation; platelet formation; megakaryocyte differentiation; erythrocyte differentiation; regulation of definitive erythrocyte differentiation; regulation of glycoprotein biosynthetic process; male gonad development; negative regulation of cell proliferation; blood coagulation; cell-cell signaling; transcription from RNA polymerase II promoter; in utero embryonic development;
GATA2negative regulation of fat cell differentiation; negative regulation of neural precursor cell proliferation; negative regulation of fat cell proliferation; semicircular canal development; definitive hemopoiesis; positive regulation of phagocytosis; homeostasis of number of cells within a tissue; neuron fate commitment; cell maturation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; negative regulation of Notch signaling pathway; positive regulation of megakaryocyte differentiation; negative regulation of macrophage differentiation; positive regulation of erythrocyte differentiation; negative regulation of myeloid cell differentiation; inner ear morphogenesis; eosinophil fate commitment; regulation of histone acetylation; somatic stem cell maintenance; pituitary gland development; central nervous system neuron development; cell differentiation in hindbrain; ventral spinal cord interneuron differentiation; blood coagulation; transcription, DNA-dependen
GATA3ventricular septum development; cardiac right ventricle morphogenesis; negative regulation of cell motility; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; lymphocyte migration; aortic valve morphogenesis; mesonephros development; kidney development; cell fate determination; negative regulation of transcription from RNA polymerase II promoter; negative regulation of endothelial cell apoptosis; response to virus; negative regulation of fat cell differentiation; positive regulation of T cell differentiation; response to estrogen stimulus; ear development; norepinephrine biosynthetic process; defense response; signal transduction; blood coagulation; negative regulation of cell proliferation; male gonad development; negative regulation of cell cycle; anatomical structure morphogenesis; positive regulation of signal transduction; positive regulation of endothelial cell migration; phosphatidylinositol 3-kinase cascade; TOR signaling cascade; positive regulation of interle
GATA5intestinal epithelial cell differentiation; positive regulation of transcription from RNA polymerase II promoter; blood coagulation
GATA6outflow tract septum morphogenesis; liver development; type B pancreatic cell differentiation; pancreatic A cell differentiation; in utero embryonic development; negative regulation of transcription from RNA polymerase II promoter; response to cAMP; positive regulation of cardioblast differentiation; positive regulation of transcription from RNA polymerase II promoter; pancreas development; negative regulation of transforming growth factor beta1 production; negative regulation of transforming growth factor beta2 production; tube morphogenesis; odontogenesis of dentin-containing tooth; response to drug; positive regulation of apoptotic process; negative regulation of apoptotic process; response to estrogen stimulus; positive regulation of angiogenesis; negative regulation of transcription, DNA-dependent; epithelial cell differentiation; organ formation; smooth muscle cell differentiation; positive regulation of BMP signaling pathway; response to toxin; male gonad development; blood coagulation; endodermal cell
GATAD2B-
GATBtranslation; glutaminyl-tRNAGln biosynthesis via transamidation; mitochondrial translation
GBA2small molecule metabolic process; glycosphingolipid metabolic process; glucosylceramide catabolic process; O-glycoside catabolic process; lipid metabolic process; sphingolipid metabolic process; bile acid metabolic process
GBF1post-Golgi vesicle-mediated transport; COPI coating of Golgi vesicle; regulation of ARF protein signal transduction; cellular membrane organization; retrograde vesicle-mediated transport, Golgi to ER
GBP4-
GBP5cellular response to interferon-gamma
GBP6-
GBP7-
GBX1regulation of transcription, DNA-dependent
GCsmall molecule metabolic process; vitamin transport; vitamin D metabolic process; steroid metabolic process
GCC1protein targeting to Golgi
GCC2recycling endosome to Golgi transport; protein targeting to Golgi; protein targeting to lysosome; protein transport; microtubule organizing center organization; protein localization in Golgi apparatus; microtubule anchoring; late endosome to Golgi transport; retrograde transport, endosome to Golgi; Golgi to plasma membrane protein transport; Golgi ribbon formation; regulation of protein exit from endoplasmic reticulum
GCDHlysine catabolic process; acyl-CoA metabolic process; fatty acid oxidation; cellular nitrogen compound metabolic process; small molecule metabolic process; fatty-acyl-CoA biosynthetic process
GCFC2negative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent
GCH1protein homooligomerization; GTP catabolic process; protein complex assembly; tetrahydrobiopterin biosynthetic process; nitric oxide biosynthetic process; induction of apoptosis; regulation of blood pressure; regulation of lung blood pressure; response to interferon-gamma; protein heterooligomerization; dihydrobiopterin metabolic process; positive regulation of nitric-oxide synthase activity; regulation of nitric-oxide synthase activity; neuromuscular process controlling posture; response to pain; tetrahydrofolate biosynthetic process; nitric oxide metabolic process; negative regulation of blood pressure; small molecule metabolic process; pteridine-containing compound biosynthetic process; dopamine biosynthetic process; vasodilation; response to tumor necrosis factor; response to lipopolysaccharide
GCHFRprotein complex assembly; nitric oxide biosynthetic process; protein heterooligomerization; regulation of nitric-oxide synthase activity; nitric oxide metabolic process; small molecule metabolic process; negative regulation of GTP cyclohydrolase I activity; neurotransmitter metabolic process; negative regulation of biosynthetic process
GCKRregulation of glucose transport; positive regulation of gene expression; response to fructose stimulus; hexose transport; carbohydrate metabolic process; cellular glucose homeostasis; transmembrane transport; triglyceride homeostasis; protein import into nucleus, translocation; glucose transport; negative regulation of glucokinase activity; positive regulation of glucokinase activity; small molecule metabolic process; urate metabolic process
GCLMsmall molecule metabolic process; negative regulation of neuron apoptosis; response to drug; positive regulation of glutamate-cysteine ligase activity; cellular nitrogen compound metabolic process; response to oxidative stress; xenobiotic metabolic process; glutathione biosynthetic process; glutamate metabolic process; cysteine metabolic process; sulfur amino acid metabolic process; response to nitrosative stress; regulation of mitochondrial depolarization; regulation of blood vessel size
GCN1regulation of translation; translation
GCNT1protein O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification
GCNT2metabolic process; multicellular organismal development; glycosaminoglycan biosynthetic process
GCNT3carbohydrate metabolic process; protein O-linked glycosylation; O-glycan processing; post-translational protein modification; cellular protein metabolic process
GDAnucleobase-containing compound metabolic process; purine base metabolic process; nervous system development; small molecule metabolic process; nucleobase-containing small molecule metabolic process; purine nucleotide catabolic process
GDAP2response to retinoic acid
GDF10response to transforming growth factor beta stimulus; positive regulation of osteoblast differentiation; ovulation cycle; growth; regulation of ossification; cerebellum development; transforming growth factor beta receptor signaling pathway; skeletal system development
GDF15signal transduction; transforming growth factor beta receptor signaling pathway; cell-cell signaling
GDF3in utero embryonic development; skeletal system development; eye development; response to dietary excess; endoderm development; mesoderm development; notochord development; somite rostral/caudal axis specification; growth; formation of anatomical boundary; primitive streak formation
GDF5embryonic limb morphogenesis; positive regulation of chondrocyte differentiation; post-embryonic hindlimb morphogenesis; forelimb morphogenesis; growth; regulation of multicellular organism growth; regulation of apoptotic process; cartilage development; transforming growth factor beta receptor signaling pathway; cell-cell signaling
GDF6positive regulation of pathway-restricted SMAD protein phosphorylation; pathway-restricted SMAD protein phosphorylation; activin receptor signaling pathway; growth; positive regulation of neuron differentiation; BMP signaling pathway; positive regulation of transcription, DNA-dependent
GDF9oocyte growth; transforming growth factor beta receptor signaling pathway; female gamete generation; positive regulation of cell proliferation; negative regulation of cell growth; regulation of progesterone secretion
GDI1signal transduction; small GTPase mediated signal transduction; protein transport; regulation of small GTPase mediated signal transduction
GDI2protein transport; signal transduction; small GTPase mediated signal transduction; regulation of small GTPase mediated signal transduction
GDNFenteric nervous system development; axon guidance; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; positive regulation of ureteric bud formation; regulation of morphogenesis of a branching structure; regulation of dopamine uptake; organ induction; postsynaptic membrane organization; anti-apoptosis; signal transduction; nervous system development; metanephros development; adult locomotory behavior; postganglionic parasympathetic nervous system development; peristalsis; neuron projection development; positive regulation of monooxygenase activity; positive regulation of dopamine secretion; negative regulation of neuron apoptosis; positive regulation of transcription from RNA polymerase II promoter; mRNA stabilization; sympathetic nervous system development; ureteric bud development; branching involved in uret
GDPD2glycerol metabolic process; lipid metabolic process
GDPD3glycerol metabolic process; lipid metabolic process
GDPD4lipid metabolic process; glycerol metabolic process
GDPD5nervous system development; glycerol metabolic process; lipid metabolic process
GEMimmune response; signal transduction; cell surface receptor signaling pathway; small GTPase mediated signal transduction; GTP catabolic process
GEMIN5protein complex assembly; ncRNA metabolic process; RNA metabolic process; gene expression; RNA splicing; spliceosomal snRNP assembly; nuclear mRNA splicing, via spliceosome
GEN1DNA repair
GET4transport; tail-anchored membrane protein insertion into ER membrane
GFAPregulation of neurotransmitter uptake; long-term synaptic potentiation; Bergmann glial cell differentiation; intermediate filament organization; intermediate filament-based process; neuron projection regeneration; extracellular matrix organization; astrocyte development; negative regulation of neuron projection development; positive regulation of Schwann cell proliferation; response to wounding
GFERspermatogenesis; cell proliferation; oxidation-reduction process
GFI1Bpositive regulation of granulocyte differentiation; positive regulation of histone H3-K9 methylation; chromatin modification; cell proliferation; multicellular organismal development; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription involved in G1 phase of mitotic cell cycle; regulation of erythrocyte differentiation; negative regulation of histone H3-K4 methylation
GFM1GTP catabolic process; mitochondrial translational elongation
GFM2GTP catabolic process; mitochondrial translation; ribosome disassembly; mitochondrial translational elongation
GFOD1-
GFPT1protein N-linked glycosylation via asparagine; cellular protein metabolic process; post-translational protein modification; endoplasmic reticulum unfolded protein response; carbohydrate biosynthetic process; metabolic process; activation of signaling protein activity involved in unfolded protein response; glutamine metabolic process; dolichol-linked oligosaccharide biosynthetic process; energy reserve metabolic process; UDP-N-acetylglucosamine biosynthetic process; fructose 6-phosphate metabolic process
GFPT2fructose 6-phosphate metabolic process; UDP-N-acetylglucosamine biosynthetic process; energy reserve metabolic process; dolichol-linked oligosaccharide biosynthetic process; glutamine metabolic process; metabolic process; protein N-linked glycosylation via asparagine; carbohydrate biosynthetic process; post-translational protein modification; cellular protein metabolic process
GFRA1cell surface receptor signaling pathway; nervous system development; axon guidance; glial cell-derived neurotrophic factor receptor signaling pathway
GFRA3neuron migration; signal transduction; nervous system development; peripheral nervous system development; sympathetic nervous system development; neuron development
GGA1intracellular protein transport; vesicle-mediated transport
GGA2vesicle-mediated transport; intracellular protein transport
GGA3vesicle-mediated transport; intracellular protein transport
GGHresponse to zinc ion; response to ethanol; response to drug; response to insulin stimulus; glutamine metabolic process
GGNgamete generation; cell differentiation; protein localization; spermatogenesis; multicellular organismal development
GGPS1cholesterol biosynthetic process; isoprenoid metabolic process; isoprenoid biosynthetic process; small molecule metabolic process
GGT5small molecule metabolic process; leukotriene biosynthetic process; metabolic process; cellular amino acid metabolic process; inflammatory response; prostanoid metabolic process; glutathione metabolic process; glutathione biosynthetic process
GGT7glutathione metabolic process; glutathione biosynthetic process; leukotriene biosynthetic process
GHDC-
GHITMapoptotic process
GHRcreatinine metabolic process; JAK-STAT cascade; positive regulation of JAK-STAT cascade; positive regulation of cell differentiation; multicellular organismal metabolic process; neuroprotection; response to peptide hormone stimulus; response to morphine; activation of JAK2 kinase activity; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of multicellular organism growth; regulation of multicellular organism growth; cellular response to hormone stimulus; cellular response to insulin stimulus; response to estradiol stimulus; response to food; receptor internalization; taurine metabolic process; hormone-mediated signaling pathway; insulin-like growth factor receptor signaling pathway; activation of MAPK activity; allantoin metabolic process; citrate metabolic process; 2-oxoglutarate metabolic process; succinate metabolic process; oxaloacetate metabolic process; isoleucine metabolic process; valine metabolic pro
GHRHadenohypophysis development; elevation of cytosolic calcium ion concentration; cAMP-mediated signaling; growth hormone secretion; positive regulation of cAMP biosynthetic process; response to food; positive regulation of multicellular organism growth; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of circadian sleep/wake cycle, non-REM sleep; positive regulation of hormone secretion; positive regulation of growth hormone secretion; negative regulation of cardiac muscle cell apoptosis; positive regulation of cell proliferation; cell-cell signaling; activation of adenylate cyclase activity by G-protein signaling pathway
GHRHRcell maturation; positive regulation of multicellular organism growth; somatotropin secreting cell development; positive regulation of growth hormone secretion; response to glucocorticoid stimulus; regulation of protein metabolic process; multicellular organismal reproductive process; positive regulation of hormone secretion; response to estrogen stimulus; positive regulation of insulin-like growth factor receptor signaling pathway; hormone metabolic process; G-protein coupled receptor signaling pathway; regulation of intracellular steroid hormone receptor signaling pathway; cellular response to insulin stimulus; response to insulin stimulus; positive regulation of cAMP biosynthetic process; water homeostasis; adenohypophysis development; cAMP-mediated signaling; determination of adult lifespan; positive regulation of cell proliferation; activation of adenylate cyclase activity by G-protein signaling pathway; lactation
GHSRadult feeding behavior; regulation of synapse assembly; negative regulation of inflammatory response; decidualization; negative regulation of insulin secretion; positive regulation of fatty acid metabolic process; negative regulation of interleukin-6 biosynthetic process; positive regulation of insulin-like growth factor receptor signaling pathway; regulation of hindgut contraction; negative regulation of tumor necrosis factor biosynthetic process; positive regulation of multicellular organism growth; cellular response to insulin stimulus; negative regulation of interleukin-1 beta production; positive regulation of appetite; response to food; growth hormone secretion; hormone-mediated signaling pathway; G-protein coupled receptor signaling pathway; actin polymerization or depolymerization; response to hormone stimulus
GIGYF1insulin-like growth factor receptor signaling pathway
GIGYF2cell death
GIMAP1T cell differentiation; B cell differentiation
GIMAP2-
GIMAP6-
GIMAP7-
GIMAP8-
GIN1DNA integration
GIPresponse to axon injury; energy reserve metabolic process; triglyceride homeostasis; positive regulation of glucagon secretion; long-term synaptic potentiation; digestive system development; regulation of insulin secretion; small molecule metabolic process; positive regulation of cAMP-mediated signaling; response to peptide hormone stimulus; response to amino acid stimulus; response to starvation; response to drug; positive regulation of insulin secretion; response to organic cyclic compound; positive regulation of glucose transport; response to selenium ion; response to glucose stimulus; response to carbohydrate stimulus; female pregnancy; signal transduction
GIPC1regulation of protein stability; regulation of synaptic plasticity; endothelial cell migration; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transforming growth factor beta receptor signaling pathway; glutamate secretion; synaptic transmission; G-protein coupled receptor signaling pathway; protein targeting
GIPC3-
GIPRactivation of adenylate cyclase activity; response to fatty acid; response to calcium ion; response to axon injury; positive regulation of insulin secretion; positive regulation of cAMP biosynthetic process; response to glucose stimulus; elevation of cytosolic calcium ion concentration; response to nutrient; activation of adenylate cyclase activity by G-protein signaling pathway; cell surface receptor signaling pathway; generation of precursor metabolites and energy; desensitization of G-protein coupled receptor protein signaling pathway
GIT1regulation of G-protein coupled receptor protein signaling pathway; regulation of ARF GTPase activity
GIT2regulation of ARF GTPase activity; regulation of G-protein coupled receptor protein signaling pathway
GJA10transmembrane transport; detection of light stimulus involved in visual perception; response to light stimulus; synapse assembly; gamete generation; synaptic transmission; cell communication
GJA4transport; response to pain; cell-cell signaling; cell communication; cell-cell junction assembly; calcium ion transport; blood vessel development
GJA8lens development in camera-type eye; transport; cell communication; visual perception
GJA9cell communication
GJB1transport; protein oligomerization; gap junction assembly; cellular membrane organization; purine ribonucleotide transport; nervous system development; cell-cell signaling
GJB3in utero embryonic development; placenta development; cell communication; sensory perception of sound; skin development
GJB4cell communication; sensory perception of smell; olfactory behavior
GJB6ear morphogenesis; sensory perception of sound; cell communication
GJB7cell communication
GJC1cellular membrane organization; cardiac muscle tissue development; cell development; gap junction assembly; visual perception; synaptic transmission; cell-cell junction assembly; muscle contraction; transport; vasculogenesis
GJC2cell-cell signaling; response to toxin; cell death; transmembrane transport
GKglycerol metabolic process; carbohydrate metabolic process; triglyceride metabolic process; triglyceride biosynthetic process; cellular lipid metabolic process; glycerol-3-phosphate biosynthetic process; small molecule metabolic process
GK2glycerol-3-phosphate metabolic process; glycerol metabolic process; carbohydrate metabolic process
GKAP1signal transduction
GKN1digestion; positive regulation of cell division; positive regulation of cell proliferation
GKN2-
GLB1galactose catabolic process; small molecule metabolic process; glycosphingolipid metabolic process; sphingolipid metabolic process; carbohydrate metabolic process
GLB1Lcarbohydrate metabolic process
GLB1L2carbohydrate metabolic process
GLCEheparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process
GLDNnervous system development; cell differentiation; multicellular organismal development
GLG1bone morphogenesis; negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of chondrocyte differentiation
GLI1negative regulation of canonical Wnt receptor signaling pathway; digestive tract morphogenesis; osteoblast differentiation; smoothened signaling pathway; multicellular organismal development; positive regulation of cell proliferation; epidermal cell differentiation; positive regulation of DNA replication; positive regulation of smoothened signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of smoothened signaling pathway
GLI2embryonic digestive tract development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of DNA replication; positive regulation of neuron differentiation; odontogenesis of dentin-containing tooth; tube development; positive regulation of T cell differentiation in thymus; negative regulation of chondrocyte differentiation; hindbrain development; mammary gland development; developmental growth; neuron development; branching morphogenesis of a tube; notochord regression; head development; prostatic bud formation; mammary gland duct morphogenesis; smoothened signaling pathway involved in dorsal/ventral neural tube patterning; cellular response to organic cyclic compound; cochlea morphogenesis; embryonic digit morphogenesis; kidney development; heart development; hindgut morphogenesis; ventral midline development; axon guidance; skeletal system development; lung development; osteoblast differentiation; in utero embryonic
GLI3neuron fate commitment; anatomical structure formation involved in morphogenesis; camera-type eye morphogenesis; developmental growth; embryonic digestive tract development; embryonic digestive tract morphogenesis; negative regulation of alpha-beta T cell differentiation; positive regulation of alpha-beta T cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of smoothened signaling pathway; anterior semicircular canal development; positive regulation of osteoblast differentiation; embryonic skeletal system morphogenesis; oligodendrocyte differentiation; inner ear development; palate development; frontal suture morphogenesis; lambdoid suture morphogenesis; sagittal suture morphogenesis; mammary gland specification; smoothened signaling pathway involved in dorsal/ventral neural tube patterning; artery development; lateral semicircular canal develop
GLIS1positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
GLIS3negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
GLMPintracellular receptor mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; regulation of RNA biosynthetic process
GLRA1synaptic transmission, glycinergic; positive regulation of acrosome reaction; regulation of inhibitory postsynaptic membrane potential; righting reflex; negative regulation of transmission of nerve impulse; regulation of action potential; startle response; regulation of respiratory gaseous exchange by neurological system process; ion transport; chloride transport; muscle contraction; neuropeptide signaling pathway; synaptic transmission; visual perception; adult walking behavior; ion transmembrane transport; regulation of membrane potential; regulation of respiratory gaseous exchange; neuromuscular process controlling posture; transmembrane transport
GLRA3synaptic transmission; ion transmembrane transport; transmembrane transport
GLRA4ion transport
GLRX5cell redox homeostasis; hemopoiesis
GLS2cellular amino acid metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; glutamine metabolic process; glutamate secretion; cellular amino acid biosynthetic process; synaptic transmission; neurotransmitter secretion
GLT1D1biosynthetic process
GLT8D1-
GLT8D2-
GLTSCR1L-
GLUD2cellular amino acid metabolic process; glutamate metabolic process; glutamate biosynthetic process; glutamate catabolic process; oxidation-reduction process
GLYATresponse to toxin; xenobiotic metabolic process; acyl-CoA metabolic process; small molecule metabolic process
GLYATL1-
GLYCTKprotein phosphorylation
GLYR1pentose-phosphate shunt
GMEB2regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter
GMFBpositive regulation of catalytic activity; nervous system development; signal transduction; protein phosphorylation
GMLnegative regulation of cell proliferation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process
GMNNnegative regulation of transcription, DNA-dependent; negative regulation of cell cycle; organ morphogenesis; negative regulation of DNA replication; protein complex assembly; mitotic cell cycle; M/G1 transition of mitotic cell cycle
GMPPApost-translational protein modification; dolichol-linked oligosaccharide biosynthetic process; biosynthetic process; GDP-mannose biosynthetic process; protein N-linked glycosylation via asparagine; cellular protein metabolic process
GNA13activation of phospholipase D activity; Rho protein signal transduction; intracellular protein kinase cascade; activation of adenylate cyclase activity by G-protein signaling pathway; regulation of cell migration; platelet activation; cell differentiation; regulation of cell shape; blood coagulation; G-protein coupled receptor signaling pathway; signal transduction; cellular component movement; GTP catabolic process; in utero embryonic development; patterning of blood vessels
GNAI1signal transduction; cell cycle; GTP catabolic process; cell division; platelet activation; blood coagulation; synaptic transmission; inhibition of adenylate cyclase activity by G-protein signaling pathway; G-protein coupled receptor signaling pathway
GNALG-protein coupled receptor signaling pathway; response to caffeine; sensory perception of smell; synaptic transmission; inhibition of adenylate cyclase activity by G-protein signaling pathway; activation of adenylate cyclase activity by dopamine receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; signal transduction; GTP catabolic process; cAMP biosynthetic process; response to amphetamine
GNAO1dopamine receptor signaling pathway; negative regulation of calcium ion transport; positive regulation of GTPase activity; response to morphine; response to drug; GTP catabolic process; muscle contraction; G-protein signaling, coupled to cAMP nucleotide second messenger; aging; locomotory behavior; regulation of heart contraction; cellular process; response to organic nitrogen; response to organic cyclic compound; forebrain development; neuron projection development; response to cytokine stimulus; response to hydrogen peroxide
GNAQpost-embryonic development; activation of phospholipase C activity by dopamine receptor signaling pathway; protein stabilization; developmental pigmentation; regulation of melanocyte differentiation; positive regulation of GTPase activity; regulation of catenin import into nucleus; embryonic digit morphogenesis; behavior; blood coagulation; heart development; glutamate receptor signaling pathway; activation of phospholipase C activity; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein coupled receptor signaling pathway; negative regulation of protein kinase activity; GTP catabolic process; regulation of action potential; skeletal system development; neuron remodeling; forebrain neuron development; platelet activation; protein ADP-ribosylation
GNASsmall molecule metabolic process; response to drug; positive regulation of osteoblast differentiation; positive regulation of osteoclast differentiation; intracellular transport; embryonic cranial skeleton morphogenesis; regulation of insulin secretion; cartilage development; transmembrane transport; cellular response to glucagon stimulus; genetic imprinting; post-embryonic body morphogenesis; tissue homeostasis; endochondral ossification; energy reserve metabolic process; cAMP biosynthetic process; GTP catabolic process; DNA methylation; water transport; G-protein coupled receptor signaling pathway; activation of adenylate cyclase activity; activation of adenylate cyclase activity by dopamine receptor signaling pathway; female pregnancy; blood coagulation; sensory perception of chemical stimulus; sensory perception of smell; behavior; protein secretion; post-embryonic development; embryonic hindlimb morphogenesis; multicellular organism growth; skin development
GNAT2retinal cone cell development; rhodopsin mediated phototransduction; detection of visible light; response to light intensity; phototransduction; visual perception; elevation of cytosolic calcium ion concentration; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor signaling pathway; GTP catabolic process; detection of chemical stimulus involved in sensory perception of bitter taste; detection of light stimulus involved in visual perception; response to stimulus
GNB1cell proliferation; cellular response to glucagon stimulus; retina development in camera-type eye; sensory perception of taste; small molecule metabolic process; platelet activation; blood coagulation; synaptic transmission; Ras protein signal transduction; G-protein coupled acetylcholine receptor signaling pathway; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; signal transduction; GTP catabolic process; energy reserve metabolic process
GNB1Lsocial behavior; G-protein coupled receptor signaling pathway; intracellular signal transduction
GNB2small molecule metabolic process; energy reserve metabolic process; GTP catabolic process; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; synaptic transmission; cellular response to glucagon stimulus
GNB3cellular response to glucagon stimulus; energy reserve metabolic process; GTP catabolic process; G-protein coupled receptor signaling pathway; synaptic transmission; small molecule metabolic process; regulation of blood pressure
GNB4cellular response to glucagon stimulus; small molecule metabolic process; energy reserve metabolic process
GNB5G-protein coupled receptor signaling pathway; signal transduction; GTP catabolic process
GNEcarbohydrate metabolic process; UDP-N-acetylglucosamine metabolic process; N-acetylneuraminate metabolic process; cell adhesion; lipopolysaccharide biosynthetic process
GNGT1eye photoreceptor cell development; cellular response to hypoxia; cardiac muscle cell apoptosis; protein localization; phototransduction; synaptic transmission; G-protein coupled receptor signaling pathway; signal transduction; GTP catabolic process
GNL2ribosome biogenesis; GTP catabolic process
GNL3Lribosome biogenesis
GNPATresponse to nutrient; response to fatty acid; small molecule metabolic process; cellular lipid metabolic process; response to starvation; myelination; response to drug; paranodal junction assembly; cerebellum morphogenesis; cellular membrane organization; phospholipid biosynthetic process; ether lipid biosynthetic process; metabolic process; synapse assembly
GNPTABcell differentiation; carbohydrate phosphorylation; protein secretion
GNSglycosaminoglycan catabolic process; keratan sulfate catabolic process
GOLGA1protein targeting to Golgi
GOLGA2positive regulation of axonogenesis; Golgi localization
GOLGA3intra-Golgi vesicle-mediated transport
GOLGA4vesicle-mediated transport; protein targeting to Golgi; Golgi to plasma membrane protein transport
GOLGA5retrograde transport, vesicle recycling within Golgi; Golgi organization; Golgi vesicle transport
GOLGA7B-
GOLGB1Golgi organization
GOLIM4transport
GOLM1-
GON4Lregulation of transcription, DNA-dependent
GOPCcytoplasmic sequestering of CFTR protein; ER to Golgi vesicle-mediated transport; Golgi to plasma membrane transport; spermatid nucleus differentiation; protein homooligomerization; regulation of catalytic activity; apical protein localization; protein transport
GORASP1mitotic cell cycle; Golgi organization; protein transport; mitotic prophase; M phase of mitotic cell cycle
GORASP2organelle organization; Golgi organization
GOSR1retrograde transport, endosome to Golgi; vesicle-mediated transport; protein transport; intra-Golgi vesicle-mediated transport; ER to Golgi vesicle-mediated transport
GOT1glutamate metabolic process; aspartate catabolic process; aspartate biosynthetic process; aspartate metabolic process; glycerol biosynthetic process; oxaloacetate metabolic process; 2-oxoglutarate metabolic process; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process; sulfur amino acid metabolic process; fatty acid homeostasis; response to glucocorticoid stimulus; small molecule metabolic process; cellular nitrogen compound metabolic process; cellular response to insulin stimulus; glutamate catabolic process to 2-oxoglutarate; glutamate catabolic process to aspartate; L-methionine salvage from methylthioadenosine; biosynthetic process; cellular amino acid biosynthetic process; polyamine metabolic process
GP2-
GP5blood coagulation; cell-matrix adhesion; blood coagulation, intrinsic pathway; negative regulation of platelet activation; platelet activation; cell adhesion
GP6platelet activation; blood coagulation; enzyme linked receptor protein signaling pathway; leukocyte migration
GPA33-
GPAA1attachment of GPI anchor to protein; protein retention in ER lumen; cellular protein metabolic process; post-translational protein modification; C-terminal protein lipidation; protein complex assembly
GPALPP1-
GPAMglycerophospholipid metabolic process; fatty acid homeostasis; response to activity; phospholipid homeostasis; negative regulation of activation-induced cell death of T cells; response to nutrient levels; interleukin-2 secretion; fatty acid metabolic process; acyl-CoA metabolic process; triglyceride biosynthetic process; response to glucose stimulus; response to fructose stimulus; positive regulation of multicellular organism growth; cellular response to insulin stimulus; metabolic process; positive regulation of activated T cell proliferation; cellular lipid metabolic process; small molecule metabolic process; response to cadmium ion; regulation of cytokine secretion; phospholipid biosynthetic process; defense response to virus; positive regulation of triglyceride biosynthetic process
GPATCH2negative regulation of phosphatase activity
GPATCH2L-
GPATCH4-
GPATCH8-
GPBP1L1regulation of transcription, DNA-dependent
GPC1axon guidance
GPC2neuron differentiation
GPC3anatomical structure morphogenesis; mesenchymal cell proliferation involved in ureteric bud development
GPC4anatomical structure morphogenesis; cell proliferation
GPC5-
GPC6-
GPD1Lcarbohydrate metabolic process; glycerol-3-phosphate catabolic process
GPD2glycerol-3-phosphate metabolic process; gluconeogenesis; NADH metabolic process; cellular lipid metabolic process; small molecule metabolic process
GPHA2-
GPIglycolysis; gluconeogenesis; glucose metabolic process; carbohydrate metabolic process; angiogenesis; hemostasis; humoral immune response; small molecule metabolic process
GPLD1hematopoietic stem cell migration; positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of apoptotic process; positive regulation of cytolysis; phosphatidylcholine metabolic process; positive regulation of membrane protein ectodomain proteolysis; positive regulation of secretion; transepithelial transport; cellular response to calcium ion; cellular response to cholesterol; cellular response to triglyceride; cellular response to pH; hematopoietic stem cell migration to bone marrow; regulation of cellular response to insulin stimulus; cellular response to insulin stimulus; ossification; cell migration involved in sprouting angiogenesis; chondrocyte differentiation; complement receptor mediated signaling pathway; GPI anchor release; negative regulation of cell proliferation; insulin receptor signaling pathway; response to glucose stimulus; positive regulation of endothelial cell migration; positive regulation of alkaline phosphatase activity; positive re
GPN3-
GPNMBnegative regulation of cell proliferation; cell adhesion
GPR1G-protein coupled receptor signaling pathway
GPR101-
GPR107-
GPR108-
GPR135-
GPR137-
GPR137B-
GPR139synaptic transmission; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; G-protein coupled receptor signaling pathway
GPR142-
GPR146-
GPR148-
GPR149-
GPR15G-protein coupled receptor signaling pathway
GPR152-
GPR153-
GPR155transmembrane transport; intracellular signal transduction
GPR156-
GPR157-
GPR158-
GPR160-
GPR161multicellular organismal development
GPR162-
GPR17G-protein coupled receptor signaling pathway
GPR174-
GPR176synaptic transmission; G-protein coupled receptor signaling pathway
GPR179-
GPR18G-protein coupled receptor signaling pathway
GPR180-
GPR182cell surface receptor signaling pathway; response to hypoxia
GPR20G-protein coupled receptor signaling pathway
GPR26activation of adenylate cyclase activity by G-protein signaling pathway
GPR27G-protein coupled receptor signaling pathway; signal transduction
GPR34intracellular protein transport; G-protein coupled receptor signaling pathway
GPR35G-protein coupled receptor signaling pathway
GPR37G-protein coupled receptor signaling pathway
GPR37L1-
GPR39G-protein coupled receptor signaling pathway
GPR45-
GPR50cell-cell signaling; G-protein coupled receptor signaling pathway
GPR55activation of phospholipase C activity; G-protein coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; bone resorption; negative regulation of osteoclast differentiation; positive regulation of ERK1 and ERK2 cascade
GPR6elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway
GPR61-
GPR62-
GPR63-
GPR65immune response; apoptotic process; positive regulation of stress fiber assembly; activation of Rho GTPase activity; actin cytoskeleton reorganization; G-protein coupled receptor signaling pathway; multicellular organismal development; response to acidity; positive regulation of cAMP biosynthetic process
GPR68G-protein coupled receptor signaling pathway; inflammatory response
GPR75G-protein coupled receptor signaling pathway
GPR78activation of adenylate cyclase activity by G-protein signaling pathway
GPR84-
GPR85G-protein coupled receptor signaling pathway; signal transduction
GPR87-
GPRASP1-
GPRC5Asignal transduction; G-protein coupled receptor signaling pathway
GPRC5CG-protein coupled receptor signaling pathway
GPRC5D-
GPRC6Aresponse to amino acid stimulus; calcium-mediated signaling
GPRIN1neuron projection development
GPRIN3-
GPSM1cell differentiation; regulation of G-protein coupled receptor protein signaling pathway; nervous system development; multicellular organismal development; signal transduction
GPSM2G-protein coupled receptor signaling pathway; establishment of mitotic spindle orientation; signal transduction; regulation of G-protein coupled receptor protein signaling pathway; lung epithelial cell differentiation
GPTgluconeogenesis; small molecule metabolic process; cellular nitrogen compound metabolic process; biosynthetic process; cellular amino acid biosynthetic process; nitrogen compound metabolic process
GPX3response to molecule of fungal origin; response to drug; hydrogen peroxide catabolic process; protein homotetramerization; response to corticosterone stimulus; oxidation-reduction process; response to organic cyclic compound; response to selenium ion; female pregnancy; response to lipid hydroperoxide; response to oxidative stress; glutathione metabolic process
GPX4phospholipid metabolic process; response to oxidative stress; multicellular organismal development; oxidation-reduction process
GRAMD1A-
GRAMD1C-
GRAMD2-
GRAMD4apoptotic process
GRASPsignal transduction; protein localization
GRB10negative regulation of Wnt receptor signaling pathway; insulin-like growth factor receptor signaling pathway; negative regulation of insulin receptor signaling pathway; negative regulation of glucose import; negative regulation of glycogen biosynthetic process; positive regulation of phosphorylation; negative regulation of phosphorylation; response to insulin stimulus; signal transduction; insulin receptor signaling pathway; positive regulation of vascular endothelial growth factor receptor signaling pathway
GRB14signal transduction; blood coagulation; intracellular signal transduction; negative regulation of insulin receptor signaling pathway; leukocyte migration
GRB7signal transduction; epidermal growth factor receptor signaling pathway; negative regulation of translation; positive regulation of cell migration; stress granule assembly; leukocyte migration; blood coagulation
GREB1-
GRHL1small molecule metabolic process; cellular lipid metabolic process; multicellular organismal development; regulation of transcription, DNA-dependent
GRHL2-
GRHPRoxidation-reduction process; glyoxylate metabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; metabolic process; excretion
GRIA1synaptic transmission; receptor internalization; long-term memory; signal transduction; ion transport
GRIA2ion transport; signal transduction; synaptic transmission
GRIA3glutamate receptor signaling pathway; synaptic transmission; regulation of receptor recycling; transport; ion transport; response to fungicide; response to lithium ion
GRIA4response to fungicide; positive regulation of synaptic transmission, glutamatergic; regulation of synaptic transmission; synaptic transmission; glutamate receptor signaling pathway; ion transport; transport
GRID1ion transport
GRID2synaptic transmission, glutamatergic; transport; ion transport; glutamate receptor signaling pathway; regulation of neuron apoptosis; prepulse inhibition; regulation of excitatory postsynaptic membrane potential
GRIK1synaptic transmission; nervous system development; central nervous system development; positive regulation of gamma-aminobutyric acid secretion; adult behavior; negative regulation of synaptic transmission, GABAergic; positive regulation of synaptic transmission, GABAergic; regulation of short-term neuronal synaptic plasticity; behavioral response to pain; regulation of synaptic transmission, glutamatergic; glutamate receptor signaling pathway; negative regulation of synaptic transmission, glutamatergic; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential; signal transduction; ion transport; transport
GRIK2negative regulation of synaptic transmission, glutamatergic; neuron apoptosis; regulation of inhibitory postsynaptic membrane potential; positive regulation of synaptic transmission; regulation of synaptic transmission; regulation of excitatory postsynaptic membrane potential; regulation of long-term neuronal synaptic plasticity; signal transduction; intracellular protein transport; glutamate receptor signaling pathway; cellular calcium ion homeostasis; ion transport; regulation of short-term neuronal synaptic plasticity; transport; behavioral fear response; synaptic transmission; regulation of JNK cascade; negative regulation of neuron apoptosis; receptor clustering; regulation of action potential in neuron; regulation of membrane potential; induction of programmed cell death in response to chemical stimulus
GRIK3glutamate receptor signaling pathway; G-protein coupled glutamate receptor signaling pathway; synaptic transmission; ionotropic glutamate receptor signaling pathway; regulation of membrane potential; negative regulation of synaptic transmission, glutamatergic; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; ion transport
GRIK4synaptic transmission; response to corticosteroid stimulus; glutamate receptor signaling pathway; ion transport; transport
GRIN1cation transport; calcium ion transmembrane transport; regulation of excitatory postsynaptic membrane potential; calcium ion homeostasis; positive regulation of transcription from RNA polymerase II promoter; response to ethanol; regulation of membrane potential; ionotropic glutamate receptor signaling pathway; visual learning; synaptic transmission; ion transport
GRIN2Aresponse to amphetamine; neurogenesis; learning; startle response; regulation of action potential; transport; ion transport; signal transduction; glutamate receptor signaling pathway; synaptic transmission; spinal cord development; learning or memory; cerebral cortex development; memory; protein localization; visual learning; response to light stimulus; response to wounding; response to carbohydrate stimulus; positive regulation of cell death; response to organic cyclic compound; hippocampus development; directional locomotion; sleep; cellular response to lipid; cellular response to growth factor stimulus; cellular response to dsRNA; cellular response to zinc ion; cellular response to manganese ion; cellular response to magnesium ion; cellular response to amino acid stimulus; response to fungicide; response to ammonium ion; regulation of excitatory postsynaptic membrane potential; regulation of sensory perception of pain; response to other organism; response to calcium ion; negative regulation of protein cata
GRIN2Bcerebral cortex development; rhythmic process; regulation of long-term neuronal synaptic plasticity; positive regulation of synaptic transmission; response to ethanol; regulation of MAPK cascade; receptor clustering; response to cocaine; response to cytokine stimulus; response to carbohydrate stimulus; multicellular organismal response to stress; response to magnesium ion; response to calcium ion; response to methylmercury; response to electrical stimulus; response to other organism; response to growth hormone stimulus; response to fungicide; cellular response to amino acid stimulus; cellular response to manganese ion; cellular response to dsRNA; cellular response to growth factor stimulus; cellular response to lipid; cellular response to organic cyclic compound; positive regulation of glutamate secretion; hippocampus development; response to acid; regulation of action potential; response to amphetamine; transport; ion transport; glutamate receptor signaling pathway; synaptic transmission; learning or memory;
GRIN2Cdirectional locomotion; response to wounding; protein localization; synaptic transmission; glutamate receptor signaling pathway; signal transduction; cation transport; ion transport; transport; ion transmembrane transport; negative regulation of protein catabolic process; regulation of membrane potential; neuromuscular process controlling balance; regulation of excitatory postsynaptic membrane potential
GRIN2Dstartle response; ion transport; signal transduction; synaptic transmission; regulation of sensory perception of pain; synaptic transmission, glutamatergic; adult locomotory behavior
GRIN3Aion transport; calcium ion transport; signal transduction; prepulse inhibition; dendrite development; response to ethanol; rhythmic process
GRIN3Bregulation of calcium ion transport; protein insertion into membrane; ionotropic glutamate receptor signaling pathway; calcium ion transmembrane transport; synaptic transmission; ion transport
GRIP1androgen receptor signaling pathway; synaptic transmission; intracellular signal transduction; positive regulation of transcription, DNA-dependent
GRIPAP1-
GRK4termination of G-protein coupled receptor signaling pathway; receptor internalization; regulation of G-protein coupled receptor protein signaling pathway; signal transduction; G-protein coupled receptor internalization
GRK7signal transduction; response to stimulus; visual perception; termination of G-protein coupled receptor signaling pathway; protein autophosphorylation
GRM1activation of MAPKK activity; activation of MAPK activity; cellular response to electrical stimulus; regulation of synaptic transmission, glutamatergic; regulation of sensory perception of pain; regulation of MAPK cascade; calcium-mediated signaling; locomotory behavior; synaptic transmission; G-protein coupled receptor signaling pathway
GRM2negative regulation of adenylate cyclase activity; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; glutamate secretion; G-protein coupled receptor signaling pathway
GRM3regulation of synaptic transmission; synaptic transmission; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; negative regulation of adenylate cyclase activity; G-protein coupled receptor signaling pathway
GRM4inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; G-protein coupled receptor signaling pathway; activation of MAPK activity; neuroprotection; synaptic transmission; neurotransmitter secretion; positive regulation of MAPK cascade
GRM5positive regulation of long-term neuronal synaptic plasticity; desensitization of G-protein coupled receptor protein signaling pathway; regulation of transcription, DNA-dependent; protein phosphorylation; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; learning; locomotory behavior; negative regulation of locomotion; activation of MAPKKK activity
GRM6synaptic transmission; retina development in camera-type eye; response to stimulus; detection of visible light; locomotory behavior; visual perception; G-protein coupled glutamate receptor signaling pathway
GRM7negative regulation of adenylate cyclase activity; response to stimulus; multicellular organismal response to stress; calcium ion transmembrane transport; negative regulation of cAMP biosynthetic process; adult behavior; negative regulation of glutamate secretion; short-term memory; sensory perception of smell; sensory perception of sound; synaptic transmission; behavioral fear response; conditioned taste aversion
GRM8G-protein coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway; visual perception; sensory perception of smell; negative regulation of cAMP biosynthetic process; synaptic transmission, glutamatergic; regulation of neurotransmitter secretion; response to stimulus
GRPsignal transduction; neuropeptide signaling pathway
GRPEL1protein import into mitochondrial matrix; protein folding
GRTP1-
GRXCR1sensory perception of sound; negative regulation of phosphatase activity; auditory receptor cell differentiation; cell redox homeostasis; post-embryonic organ morphogenesis; inner ear development; vestibular receptor cell development; inner ear receptor stereocilium organization; inner ear receptor cell development
GSAP-
GSDMB-
GSDMD-
GSE1-
GSG1-
GSG1L-
GSK3Anegative regulation of glycogen biosynthetic process; positive regulation of protein catabolic process; positive regulation of heart contraction; positive regulation of transcription from RNA polymerase II promoter; negative regulation of glucose import; negative regulation of insulin receptor signaling pathway; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; negative regulation of transferase activity; negative regulation of cell growth involved in cardiac muscle cell development; cellular response to lithium ion; cellular response to organic cyclic compound; positive regulation of adrenergic receptor signaling pathway; negative regulation of canonical Wnt receptor signaling pathway; positive regulation of glycogen (starch) synthase activity; negative regulation of glycogen (starch) synthase activity; protein phosphorylation; negative regulation of type B pancreatic cell development; positive regulation of peptidyl-serine phosphorylation; glycogen metabolic process; r
GSK3Bregulation of microtubule-based process; intracellular signal transduction; negative regulation of apoptotic process; negative regulation of signal transduction; negative regulation of glycogen biosynthetic process; positive regulation of protein catabolic process; positive regulation of protein export from nucleus; nerve growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; negative regulation of NFAT protein import into nucleus; canonical Wnt receptor signaling pathway; superior temporal gyrus development; negative regulation of canonical Wnt receptor signaling pathway; negative regulation of type B pancreatic cell development; negative regulation of glycogen (starch) synthase activity; nervous system development; epithelial to mesenchymal transition; positive regulation of cell-matrix adhesion; carbohydrate metabolic process; glycogen metabolic process; protein phosphorylation; ER overload response; epidermal growth factor receptor signaling pathway; multicellular organismal de
GSKIP-
GSSaging; glutathione biosynthetic process; xenobiotic metabolic process; response to oxidative stress; nervous system development; small molecule metabolic process; response to cadmium ion; response to amino acid stimulus; response to tumor necrosis factor; response to nutrient levels; response to xenobiotic stimulus; cellular amino acid metabolic process
GSTA4small molecule metabolic process; metabolic process; xenobiotic metabolic process; glutathione metabolic process
GSTM2xenobiotic catabolic process; metabolic process; glutathione metabolic process
GSTO1oxidation-reduction process; metabolic process; xenobiotic metabolic process; cellular response to arsenic-containing substance; small molecule metabolic process; xenobiotic catabolic process; L-ascorbic acid biosynthetic process; L-ascorbic acid metabolic process
GSTP1negative regulation of leukocyte proliferation; cellular response to lipopolysaccharide; cellular response to epidermal growth factor stimulus; cellular response to glucocorticoid stimulus; cellular response to cell-matrix adhesion; negative regulation of monocyte chemotactic protein-1 production; negative regulation of MAPK cascade; positive regulation of superoxide anion generation; response to L-ascorbic acid; common myeloid progenitor cell proliferation; nitric oxide storage; regulation of phosphorylation; negative regulation of apoptotic process; negative regulation of I-kappaB kinase/NF-kappaB cascade; response to amino acid stimulus; negative regulation of MAP kinase activity; negative regulation of acute inflammatory response; negative regulation of JUN kinase activity; small molecule metabolic process; response to ethanol; negative regulation of fibroblast proliferation; negative regulation of nitric-oxide synthase biosynthetic process; negative regulation of necrotic cell death; regulation of ERK1 a
GSTZ1L-phenylalanine catabolic process; tyrosine catabolic process; glutathione metabolic process; aromatic amino acid family metabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process
GSX1neuron fate commitment; spinal cord association neuron differentiation; hypothalamus development; multicellular organismal development; adenohypophysis development; positive regulation of transcription from RNA polymerase II promoter
GSX2multicellular organismal development
GTDC1biosynthetic process
GTF2Bgene expression; interspecies interaction between organisms; viral reproduction; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
GTF2E1regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; gene expression; viral reproduction; interspecies interaction between organisms
GTF2E2transcription initiation from RNA polymerase II promoter; viral reproduction; gene expression; transcription elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
GTF2F1positive regulation of transcription from RNA polymerase II promoter; positive regulation of viral transcription; viral reproduction; gene expression; response to virus; RNA splicing; mRNA capping; transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; transcription elongation from RNA polymerase II promoter
GTF2F2transcription from RNA polymerase II promoter; positive regulation of viral transcription; positive regulation of transcription from RNA polymerase II promoter; viral reproduction; gene expression; RNA splicing; mRNA capping; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; nuclear mRNA splicing, via spliceosome
GTF2H3termination of RNA polymerase I transcription; nucleotide-excision repair, DNA damage removal; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; mRNA capping; translation; positive regulation of viral transcription; viral reproduction; gene expression; protein phosphorylation; transcription initiation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; regulation of transcription, DNA-dependent; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; DNA repair; transcription elongation from RNA polymerase I promoter
GTF3C1transcription from RNA polymerase III promoter; tRNA transcription; transcription, DNA-dependent; gene expression; 5S class rRNA transcription from RNA polymerase III type 1 promoter; tRNA transcription from RNA polymerase III promoter; rRNA transcription
GTF3C2transcription, DNA-dependent; transcription from RNA polymerase III promoter; gene expression; 5S class rRNA transcription from RNA polymerase III type 1 promoter; tRNA transcription from RNA polymerase III promoter
GTF3C4transcription initiation from RNA polymerase III promoter; gene expression; histone acetylation; 5S class rRNA transcription from RNA polymerase III type 1 promoter; transcription from RNA polymerase III promoter; transcription, DNA-dependent; positive regulation of catalytic activity; tRNA transcription from RNA polymerase III promoter
GTPBP2-
GTPBP4GTP catabolic process; negative regulation of DNA replication; negative regulation of cell proliferation; negative regulation of cell-cell adhesion; negative regulation of cell migration; negative regulation of protein ubiquitination; negative regulation of collagen binding; ribosome biogenesis; protein stabilization; regulation of cyclin-dependent protein kinase activity
GTSF1-
GUCA1Aresponse to stimulus; signal transduction; visual perception
GUCA1Csignal transduction; visual perception
GUCD1-
GUCY1A2cGMP biosynthetic process; signal transduction; blood coagulation; intracellular signal transduction
GUCY1A3cGMP biosynthetic process; nitric oxide mediated signal transduction; blood coagulation; intracellular signal transduction; blood circulation
GUCY2Cregulation of cell proliferation; intracellular signal transduction; response to toxin; receptor guanylyl cyclase signaling pathway; cGMP biosynthetic process
GUCY2Dreceptor guanylyl cyclase signaling pathway; visual perception; intracellular signal transduction; response to stimulus; cGMP biosynthetic process
GUCY2FcGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; visual perception; intracellular signal transduction; response to stimulus
GUF1translation
GXYLT1O-glycan processing
GYPAcytoskeletal anchoring at plasma membrane; interspecies interaction between organisms; regulation of response to osmotic stress
GYS1small molecule metabolic process; carbohydrate metabolic process; glycogen biosynthetic process; glucose metabolic process; heart development
GYS2carbohydrate metabolic process; glycogen biosynthetic process; glucose metabolic process; generation of precursor metabolites and energy; response to glucose stimulus; small molecule metabolic process
GZF1negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; branching involved in ureteric bud morphogenesis
GZMAcleavage of lamin; proteolysis involved in cellular protein catabolic process; negative regulation of oxidoreductase activity; negative regulation of DNA binding; positive regulation of apoptotic process; negative regulation of endodeoxyribonuclease activity; cytolysis; immune response; apoptotic process
GZMBproteolysis; apoptotic process; cleavage of lamin; induction of apoptosis by intracellular signals; activation of pro-apoptotic gene products; cytolysis
H1FNTsperm chromatin condensation; multicellular organismal development; spermatogenesis; spermatid nucleus elongation; cell differentiation; chromosome condensation
H1FOOmeiosis; nucleosome assembly
H6PDcarbohydrate metabolic process; glucose metabolic process; pentose-phosphate shunt; NADP metabolic process
HAAOneuron homeostasis; response to cadmium ion; small molecule metabolic process; tryptophan catabolic process; response to zinc ion; pyridine nucleotide biosynthetic process; quinolinate biosynthetic process; cellular nitrogen compound metabolic process
HABP2proteolysis; cell adhesion
HACD4fatty acid biosynthetic process
HACE1protein modification process; Rac protein signal transduction; regulation of cell migration; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; protein ubiquitination; cell cycle; cellular membrane fusion; regulation of transcription, DNA-dependent; Golgi organization
HADHfatty acid metabolic process; small molecule metabolic process; fatty acid beta-oxidation; response to hormone stimulus; response to activity; response to insulin stimulus; response to drug; cellular lipid metabolic process; negative regulation of insulin secretion
HADHAsmall molecule metabolic process; cellular lipid metabolic process; response to drug; response to insulin stimulus; fatty acid beta-oxidation; fatty acid metabolic process
HADHBfatty acid metabolic process; fatty acid beta-oxidation; small molecule metabolic process; oxidation-reduction process; cellular lipid metabolic process
HAMPdefense response to fungus; immune response; killing of cells of other organism; cellular iron ion homeostasis; defense response to bacterium
HAND1negative regulation of transcription from RNA polymerase II promoter; heart development; embryonic heart tube development; odontogenesis of dentin-containing tooth; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; ventricular cardiac muscle tissue morphogenesis; cardiac septum morphogenesis; mesenchyme development; trophoblast giant cell differentiation; cartilage morphogenesis; multicellular organismal development; transcription from RNA polymerase II promoter; cardiac right ventricle formation; cardiac left ventricle formation; heart looping; trophectodermal cell differentiation; blastocyst development; angiogenesis; mesoderm formation
HAO1glyoxylate metabolic process; glycolate catabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; response to oxidative stress; fatty acid alpha-oxidation
HAP1synaptic transmission; brain development; protein localization
HAPLN1cell adhesion
HAPLN3cell adhesion
HAPLN4cell adhesion
HARBI1-
HARS2gene expression; translation; tRNA aminoacylation for protein translation; histidyl-tRNA aminoacylation
HAS2hyaluronan biosynthetic process; positive regulation of urine volume; renal water absorption
HAS3carbohydrate metabolic process; hyaluronan biosynthetic process; positive regulation of transcription, DNA-dependent
HAUS3cell cycle; spindle assembly; centrosome organization; mitosis; cell division
HAUS4mitosis; cell cycle; centrosome organization; cell division; spindle assembly
HAUS7mitosis; cell division; cell cycle; centrosome organization; spindle assembly
HAVCR1interspecies interaction between organisms
HAVCR2-
HAX1-
HBS1Ltranslation; signal transduction
HCAR1response to estradiol stimulus
HCFC1negative regulation of transcription from RNA polymerase II promoter; protein stabilization; positive regulation of cell cycle; interspecies interaction between organisms; histone H4-K16 acetylation; histone H4-K8 acetylation; histone H4-K5 acetylation; regulation of protein complex assembly; reactivation of latent virus; positive regulation of gene expression; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
HCKleukocyte degranulation; negative regulation of apoptotic process; interspecies interaction between organisms; innate immune response; respiratory burst after phagocytosis; protein autophosphorylation; regulation of defense response to virus by virus; regulation of inflammatory response; regulation of phagocytosis; defense response to Gram-positive bacterium; regulation of sequence-specific DNA binding transcription factor activity; interferon-gamma-mediated signaling pathway; regulation of podosome assembly; positive regulation of actin cytoskeleton reorganization; lipopolysaccharide-mediated signaling pathway; leukocyte migration involved in immune response; innate immune response-activating signal transduction; protein phosphorylation; exocytosis; cell adhesion; integrin-mediated signaling pathway; mesoderm development; positive regulation of cell proliferation; regulation of cell shape; viral reproduction; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; positive regulation of actin
HCLS1regulation of transcription, DNA-dependent; positive regulation of cell proliferation; response to hormone stimulus; erythrocyte differentiation; intracellular signal transduction; positive regulation of tyrosine phosphorylation of STAT protein
HCN1transmembrane transport; ion transport; apical protein localization; retinal cone cell development; potassium ion transport; synaptic transmission; potassium ion transmembrane transport
HCN3transmembrane transport; ion transport; potassium ion transport; synaptic transmission
HCRTR1neuropeptide signaling pathway; synaptic transmission; feeding behavior
HCRTR2neuropeptide signaling pathway; feeding behavior; synaptic transmission; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
HCSTregulation of immune response
HDAC1negative regulation of apoptotic process; embryonic digit morphogenesis; negative regulation by host of viral transcription; interspecies interaction between organisms; negative regulation of cell cycle; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nerve growth factor receptor signaling pathway; negative regulation of androgen receptor signaling pathway; hair follicle placode formation; eyelid development in camera-type eye; fungiform papilla formation; histone H3 deacetylation; histone H4 deacetylation; odontogenesis of dentin-containing tooth; negative regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; chromatin remodeling; regulation of transcription, DNA-dependent; protein deacetylation; anti-apoptosis; blood coagulation; epidermal cell differentiation; negative regulation of myotube differentiation; positive regulation of receptor biosynthetic pr
HDAC10regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; oligodendrocyte development; protein deacetylation; negative regulation of transcription, DNA-dependent; histone deacetylation; chromatin modification
HDAC2embryonic digit morphogenesis; negative regulation of apoptotic process; negative regulation of MHC class II biosynthetic process; negative regulation of cell cycle; positive regulation of proteolysis; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; nerve growth factor receptor signaling pathway; hair follicle placode formation; eyelid development in camera-type eye; fungiform papilla formation; negative regulation of sequence-specific DNA binding transcription factor activity; positive regulation of collagen biosynthetic process; odontogenesis of dentin-containing tooth; histone deacetylation; dendrite development; negative regulation of neuron projection development; positive regulation of receptor biosynthetic process; epidermal cell differentiation; positive regulation of cell proliferation; blood coagulation; maintenance of chromatin silencing; chromatin remodeling; negative reg
HDAC4skeletal system development; osteoblast development; chromatin remodeling; negative regulation of transcription from RNA polymerase II promoter; inflammatory response; negative regulation of myotube differentiation; regulation of cardiac muscle contraction by calcium ion signaling; response to denervation involved in regulation of muscle adaptation; negative regulation of cell proliferation; B cell activation; positive regulation of cell proliferation; nervous system development; chromatin modification; histone H4 deacetylation; histone H3 deacetylation; response to interleukin-1; positive regulation of sequence-specific DNA binding transcription factor activity; regulation of skeletal muscle fiber development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of glycolysis; negative regulation of osteoblast differentiation; regulation of protein binding; negative r
HDAC5chromatin modification; negative regulation of transcription from RNA polymerase II promoter; regulation of protein binding; chromatin organization; chromatin remodeling; chromatin silencing; inflammatory response; regulation of myotube differentiation; negative regulation of myotube differentiation; positive regulation of sequence-specific DNA binding transcription factor activity; histone deacetylation; B cell differentiation; negative regulation of cell migration involved in sprouting angiogenesis; cellular response to insulin stimulus; B cell activation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
HDAC6regulation of microtubule-based movement; cellular response to topologically incorrect protein; positive regulation of apoptotic process; protein polyubiquitination; protein deacetylation; negative regulation of protein complex disassembly; negative regulation of proteolysis; negative regulation of transcription, DNA-dependent; negative regulation of oxidoreductase activity; response to misfolded protein; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; regulation of androgen receptor signaling pathway; cellular response to hydrogen peroxide; aggresome assembly; polyubiquitinated misfolded protein transport; Hsp90 deacetylation; response to growth factor stimulus; cellular response to misfolded protein; positive regulation of chaperone-mediated protein complex assembly; tubulin deacetylation; lysosome localization; misfolded or incompletely synthesized protein catabolic process; intracellular protein transport; negative regulation of microtubule depolymerization; resp
HDChistamine metabolic process; small molecule metabolic process; catecholamine biosynthetic process; cellular nitrogen compound metabolic process; histidine catabolic process; histidine metabolic process; cellular amino acid metabolic process
HDGFregulation of transcription, DNA-dependent; activation of signaling protein activity involved in unfolded protein response; signal transduction; cell proliferation; cellular process; endoplasmic reticulum unfolded protein response
HDGFRP2-
HDGFRP3-
HDLBPcholesterol metabolic process; steroid metabolic process; transport; lipid transport
HDX-
HEATR1rRNA processing
HEATR3-
HEATR4-
HEATR5B-
HEATR6-
HECArespiratory tube development; multicellular organismal development
HECTD2protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process
HECTD3protein ubiquitination involved in ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; protein modification process
HECW1protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process
HECW2protein modification process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process
HELBDNA replication, synthesis of RNA primer; DNA replication
HELQ-
HELTmulticellular organism growth; suckling behavior; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; GABAergic neuron differentiation in basal ganglia; central nervous system development; multicellular organismal aging; post-embryonic development
HELZ-
HELZ2-
HEMGNmulticellular organismal development; cell differentiation; regulation of osteoblast differentiation
HEMK1DNA methylation
HEPACAMcell cycle arrest; cell adhesion; regulation of growth; cell cycle
HEPACAM2-
HEPHcellular iron ion homeostasis; erythrocyte differentiation; transmembrane transport; copper ion transport; ion transport
HERC2protein ubiquitination; spermatogenesis; intracellular protein transport; protein modification process; DNA repair; protein ubiquitination involved in ubiquitin-dependent protein catabolic process
HERC3protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein modification process
HERC5response to virus; regulation of cyclin-dependent protein kinase activity; cytokine-mediated signaling pathway; ISG15-protein conjugation; negative regulation of type I interferon production; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; innate immune response; regulation of defense response to virus
HERPUD1cellular calcium ion homeostasis; response to stress; response to unfolded protein; activation of signaling protein activity involved in unfolded protein response; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; endoplasmic reticulum unfolded protein response
HERPUD2response to unfolded protein; spermatogenesis
HES1regulation of fat cell differentiation; neural tube development; adenohypophysis development; lung development; positive regulation of BMP signaling pathway; midbrain development; endocrine pancreas development; somatic stem cell maintenance; positive regulation of T cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein; auditory receptor cell fate determination; positive regulation of DNA binding; cell fate commitment; trochlear nerve development; negative regulation of auditory receptor cell differentiation; positive regulation of Notch signaling pathway; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; lateral inhibition; positive regulation of JAK-STAT cascade; cell maturation; thymus development; outflow tract morphogenesis; positive regulation of cell proliferation; nervous system development; pattern specification process; STAT protein import into nucleus; smoothened signaling pathway; Notch signali
HES5comma-shaped body morphogenesis; cell maturation; negative regulation of transcription from RNA polymerase II promoter; auditory receptor cell differentiation; central nervous system myelination; protein complex assembly; cell adhesion; Notch signaling pathway; smoothened signaling pathway; multicellular organismal development; brain development; positive regulation of cell proliferation; oligodendrocyte development; telencephalon development; glial cell fate commitment; neural tube development; positive regulation of JAK-STAT cascade; positive regulation of BMP signaling pathway; regulation of myelination; chondrocyte differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein; auditory receptor cell fate determination; camera-type eye development; regulation of cell differentiation; negative regulation of neuron differentiation; positive regulation of Notch signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase I
HEXDCcarbohydrate metabolic process
HEXIM2negative regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cyclin-dependent protein kinase activity
HEYLpositive regulation of neuron differentiation; glomerulus development; proximal tubule development; multicellular organismal development; Notch signaling pathway; epithelial to mesenchymal transition involved in endocardial cushion formation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of androgen receptor signaling pathway; cellular response to BMP stimulus; negative regulation of androgen receptor activity
HFE2axon guidance
HFM1-
HGDtyrosine catabolic process; small molecule metabolic process; cellular nitrogen compound metabolic process; L-phenylalanine catabolic process; cellular amino acid metabolic process
HGFplatelet activation; positive regulation of DNA biosynthetic process; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; cell chemotaxis; myoblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; hepatocyte growth factor receptor signaling pathway; cellular response to hepatocyte growth factor stimulus; organ regeneration; blood coagulation; mitosis; anti-apoptosis; proteolysis; platelet degranulation; liver development; epithelial to mesenchymal transition; cell morphogenesis; activation of MAPK activity
HGSnegative regulation of JAK-STAT cascade; negative regulation of cell proliferation; endosome to lysosome transport; negative regulation of epidermal growth factor receptor signaling pathway; regulation of protein catabolic process; epidermal growth factor receptor signaling pathway; cellular membrane organization; endosome transport; intracellular protein transport; signal transduction
HHATmulticellular organismal development
HHATLnegative regulation of N-terminal protein palmitoylation
HHIPskeletal system morphogenesis; carbohydrate metabolic process; neuroblast proliferation; dorsal/ventral pattern formation; negative regulation of signal transduction; regulation of fibroblast growth factor receptor signaling pathway; negative regulation of smoothened signaling pathway; epithelial tube branching involved in lung morphogenesis
HHIPL2carbohydrate metabolic process
HHLA3-
HIBADHsmall molecule metabolic process; cellular nitrogen compound metabolic process; branched chain family amino acid catabolic process; valine metabolic process; pentose-phosphate shunt
HIC2negative regulation of transcription, DNA-dependent
HIF1Aregulation of transcription from RNA polymerase II promoter in response to oxidative stress; positive regulation of epithelial cell migration; mRNA transcription from RNA polymerase II promoter; glucose homeostasis; hemoglobin biosynthetic process; embryonic hemopoiesis; collagen metabolic process; regulation of transforming growth factor beta2 production; cellular response to insulin stimulus; positive regulation of chemokine production; oxygen homeostasis; positive regulation of vascular endothelial growth factor receptor signaling pathway; negative regulation of bone mineralization; neural fold elevation formation; response to muscle activity; positive regulation of receptor biosynthetic process; cell differentiation; positive regulation of smooth muscle cell proliferation; negative regulation of mesenchymal cell apoptosis; cellular response to hypoxia; cellular response to interleukin-1; positive regulation of chemokine-mediated signaling pathway; elastin metabolic process; cartilage development; positive
HIF1ANregulation of transcription, DNA-dependent; peptidyl-asparagine hydroxylation; oxidation-reduction process
HIF3Aresponse to hypoxia; positive regulation of transcription from RNA polymerase II promoter
HINFPDNA damage checkpoint; positive regulation of transcription, DNA-dependent; G1/S transition of mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; in utero embryonic development; DNA repair; regulation of transcription, DNA-dependent; regulation of gene expression; positive regulation of gene expression; negative regulation of gene expression; establishment of protein localization; myoblast differentiation; negative regulation of transcription, DNA-dependent
HINT2apoptotic process; steroid biosynthetic process
HIP1regulation of transcription, DNA-dependent; endocytosis; apoptotic process; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process; cell death; cell differentiation; regulation of apoptotic process; positive regulation of receptor-mediated endocytosis; clathrin coat assembly
HIP1Rreceptor-mediated endocytosis
HIPK1eye development; regulation of tumor necrosis factor-mediated signaling pathway; regulation of transcription, DNA-dependent; apoptotic process; positive regulation of angiogenesis; definitive hemopoiesis
HIPK3protein phosphorylation; apoptotic process; anti-apoptosis; mRNA transcription; peptidyl-serine phosphorylation; regulation of transcription, DNA-dependent; peptidyl-threonine phosphorylation; negative regulation of JUN kinase activity
HIPK4-
HIRAchromatin modification; anatomical structure morphogenesis; gastrulation; regulation of transcription from RNA polymerase II promoter
HIRIP3chromatin assembly or disassembly
HIST1H1Bnucleosome assembly
HIST1H1Cnucleosome positioning; nucleosome assembly
HIST1H1Tnucleosome assembly; multicellular organismal development; spermatogenesis; binding of sperm to zona pellucida; cell differentiation; sperm motility
HIST1H2ADnucleosome assembly
HIST1H2AGnucleosome assembly
HIST1H2AKnucleosome assembly
HIST1H2AM-
HIST1H2BBnucleosome assembly
HIST1H2BDnucleosome assembly
HIST1H2BI-
HIST1H3A-
HIST1H3C-
HIST1H3I-
HIST1H3J-
HIST1H4F-
HIST1H4Gnucleosome assembly
HIST1H4L-
HIST2H2ABnucleosome assembly
HIST3H3telomere maintenance; nucleosome assembly
HIVEP1negative regulation of transcription from RNA polymerase II promoter
HIVEP2regulation of transcription, DNA-dependent
HIVEP3positive regulation of transcription, DNA-dependent
HJURPregulation of DNA binding; regulation of protein complex assembly; nucleosome assembly; cell cycle; chromosome segregation; centromeric core chromatin assembly; CenH3-containing nucleosome assembly at centromere
HK2hexose transport; glucose transport; apoptotic mitochondrial changes; lactation; glycolysis; glucose metabolic process; carbohydrate metabolic process; small molecule metabolic process; regulation of glucose import; carbohydrate phosphorylation; transmembrane transport
HKDC1glycolysis; carbohydrate metabolic process
HKR1multicellular organismal development; regulation of transcription, DNA-dependent
HLA-DQB1B cell affinity maturation; T cell receptor signaling pathway; interferon-gamma-mediated signaling pathway; cellular response to interferon-gamma; antigen processing and presentation of peptide antigen; positive regulation of alpha-beta T cell activation; T cell costimulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokine-mediated signaling pathway; immune response; positive regulation of T-helper 1 type immune response; positive regulation of antigen processing and presentation; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
HLCScell proliferation; protein biotinylation; histone modification; response to biotin; histone biotinylation
HLFtranscription from RNA polymerase II promoter; multicellular organismal development; rhythmic process
HLTFchromatin modification; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent
HLXskeletal muscle tissue development; embryonic digestive tract morphogenesis; enteric nervous system development; positive regulation of organ growth; negative regulation of T-helper 2 cell differentiation; cell differentiation; positive regulation of cell proliferation; positive regulation of T-helper 1 cell differentiation; multicellular organismal development; liver development
HM13membrane protein proteolysis
HMBOX1positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent
HMCN1response to stimulus; visual perception
HMG20Achromatin modification; regulation of transcription, DNA-dependent; chromatin organization
HMGCLL1-
HMGCRcoenzyme A metabolic process; small molecule metabolic process; cellular lipid metabolic process; gonad development; germ cell migration; isoprenoid biosynthetic process; cholesterol biosynthetic process
HMGCS1cellular response to follicle-stimulating hormone stimulus; response to lipoprotein stimulus; response to tellurium ion; small molecule metabolic process; cellular lipid metabolic process; response to drug; response to gonadotropin stimulus; response to purine-containing compound; response to organic nitrogen; response to low light intensity stimulus; male gonad development; isoprenoid biosynthetic process; brain development; cholesterol biosynthetic process; lipid metabolic process; liver development; response to acid; response to vitamin E; cellular response to organic cyclic compound; cellular response to cholesterol
HMGCS2cellular response to hormone stimulus; small molecule metabolic process; multicellular organismal response to stress; response to testosterone stimulus; response to glucagon stimulus; response to triglyceride; response to monosaccharide stimulus; response to prostaglandin F stimulus; response to drug; response to starvation; cellular lipid metabolic process; response to ethanol; cellular ketone body metabolic process; ketone body biosynthetic process; response to cAMP; response to growth hormone stimulus; adipose tissue development; response to linoleic acid; cellular response to lipopolysaccharide; cellular response to amino acid stimulus; cellular response to glucocorticoid stimulus; cellular response to fatty acid; cellular response to organic cyclic compound; kidney development; lung development; response to metal ion; cellular response to insulin stimulus; liver development; cholesterol biosynthetic process; brain development; midgut development; response to nutrient; isoprenoid biosynthetic process; res
HMGN3regulation of insulin secretion involved in cellular response to glucose stimulus; chromatin modification; positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter
HMGN4-
HMGN5positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; chromatin modification
HMGXB4endosome to lysosome transport; negative regulation of Wnt receptor signaling pathway
HMHA1regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
HMOX1cellular iron ion homeostasis; response to oxidative stress; heme oxidation; porphyrin-containing compound metabolic process; negative regulation of leukocyte migration; wound healing involved in inflammatory response; endothelial cell proliferation; angiogenesis; smooth muscle hyperplasia; negative regulation of mast cell degranulation; positive regulation of I-kappaB kinase/NF-kappaB cascade; response to hydrogen peroxide; heme catabolic process; response to nicotine; low-density lipoprotein particle clearance; erythrocyte homeostasis; negative regulation of mast cell cytokine production; cellular response to nutrient; anti-apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; cell death; regulation of blood pressure; excretion; small GTPase mediated signal transduction; intracellular protein kinase cascade; signal transduction; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of DNA binding; response to stimulus; regu
HMX2multicellular organismal development; nervous system development; brain development; positive regulation of cell proliferation; cell differentiation; inner ear morphogenesis
HN1L-
HNF1Apositive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; glucose import; regulation of hormone secretion; paraxial mesoderm formation; reproductive structure development; regulation of insulin secretion; positive regulation of transcription initiation from RNA polymerase II promoter; SMAD protein signal transduction; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; placenta development; liver development; blastocyst development; regulation of pronephros size; insulin secretion; bile acid biosynthetic process; heme biosynthetic process; response to oxidative stress; protein localization; cholesterol metabolic process; response to glucose stimulus; bile acid and bile salt transport; fatty acid transport; fatty acid biosynthetic process; regulation of Wnt receptor signaling pathway; embryonic limb morphogenesis; endocrine pancreas development; renal glucose abso
HNF1Bhindbrain development; mesonephric duct formation; mesonephric duct development; regulation of branch elongation involved in ureteric bud branching; hepatoblast differentiation; ureteric bud elongation; epithelium development; positive regulation of transcription initiation from RNA polymerase II promoter; epithelial cell proliferation; genitalia development; pronephros development; branching morphogenesis of a tube; embryonic digestive tract morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; pronephric nephron tubule development; endocrine pancreas development; insulin secretion; anterior/posterior pattern specification; response to glucose stimulus; endoderm development; inner cell mass cell differentiation; regulation of Wnt receptor signaling pathway; kidney development; negative regulation of transcription from RNA polymerase II promoter; regulation of pronephros size; regulati
HNF4Aestablishment of tissue polarity; sex differentiation; phospholipid homeostasis; positive regulation of fatty acid biosynthetic process; positive regulation of transcription, DNA-dependent; negative regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; negative regulation of peptidyl-tyrosine phosphorylation; regulation of insulin secretion; response to cAMP; lipid homeostasis; blood coagulation; SMAD protein signal transduction; regulation of growth hormone receptor signaling pathway; triglyceride homeostasis; positive regulation of cholesterol homeostasis; xenobiotic metabolic process; acyl-CoA metabolic process; ornithine metabolic process; regulation of transcription from RNA polymerase II promoter; cell-cell junction organization; negative regulation of cell proliferation; response to glucose stimulus; gene expression; regulation of gastrulation; regulation of lipid metabolic process; signal transduction involved in regulation of gene expression; cell dif
HNF4Gpositive regulation of transcription, DNA-dependent; endocrine pancreas development; gene expression; regulation of transcription from RNA polymerase II promoter
HNMTresponse to tumor cell; response to interleukin-1; response to glucocorticoid stimulus; response to cocaine; response to amine stimulus; respiratory gaseous exchange; brain development; hyperosmotic response; response to stress
HNRNPA2B1RNA transport; gene expression; RNA splicing; mRNA processing; nuclear mRNA splicing, via spliceosome
HNRNPA3RNA splicing; nuclear mRNA splicing, via spliceosome; mRNA transport; gene expression
HNRNPABepithelial to mesenchymal transition; positive regulation of transcription, DNA-dependent
HNRNPCnuclear mRNA splicing, via spliceosome; gene expression; RNA splicing
HNRNPDnuclear mRNA splicing, via spliceosome; mRNA stabilization; positive regulation of transcription, DNA-dependent; mRNA metabolic process; RNA metabolic process; gene expression; RNA splicing; RNA catabolic process; RNA processing; regulation of transcription, DNA-dependent
HNRNPDL-
HNRNPFnuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing; regulation of RNA splicing; gene expression
HNRNPH3RNA splicing; RNA processing; nuclear mRNA splicing, via spliceosome
HNRNPMgene expression; RNA splicing; alternative nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome
HNRNPRmRNA processing; RNA splicing; gene expression; nuclear mRNA splicing, via spliceosome
HNRNPUL1gene expression; response to virus; RNA splicing; nuclear mRNA splicing, via spliceosome; RNA processing; regulation of transcription, DNA-dependent
HNRNPUL2-
HOMER1activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway; synaptic transmission; positive regulation of signal transduction; response to calcium ion; regulation of store-operated calcium entry; regulation of cation channel activity
HOOK1spermatid development; cell differentiation; protein transport; microtubule cytoskeleton organization; endosome organization; lysosome organization; multicellular organismal development; spermatogenesis; endosome to lysosome transport; early endosome to late endosome transport
HOOK2early endosome to late endosome transport; endocytosis; protein transport; endosome to lysosome transport; lysosome organization; endosome organization; microtubule cytoskeleton organization
HOOK3Golgi localization; endosome to lysosome transport; protein transport; interkinetic nuclear migration; protein localization to centrosome; cytoplasmic microtubule organization; negative regulation of neurogenesis; endosome organization; lysosome organization; early endosome to late endosome transport; microtubule anchoring at centrosome; microtubule anchoring
HOPXnegative regulation of cell differentiation; multicellular organismal development; trophectodermal cell differentiation
HOXA11embryonic limb morphogenesis; positive regulation of chondrocyte differentiation; embryonic digit morphogenesis; positive regulation of transcription, DNA-dependent; developmental growth; cartilage development involved in endochondral bone morphogenesis; positive regulation of cell development; proximal/distal pattern formation; dorsal/ventral pattern formation; anterior/posterior pattern specification; anatomical structure morphogenesis; mesodermal cell fate specification; multicellular organismal development; organ induction; branching involved in ureteric bud morphogenesis; metanephros development; skeletal system development
HOXA2negative regulation of neuron differentiation; cell fate determination; negative regulation of transcription from RNA polymerase II promoter; embryonic skeletal system morphogenesis; embryonic viscerocranium morphogenesis; positive regulation of transcription from RNA polymerase II promoter; middle ear morphogenesis; brain segmentation; rhombomere 3 morphogenesis; rhombomere 2 development; dorsal/ventral pattern formation; anterior/posterior pattern specification; motor axon guidance; segment specification; osteoblast development
HOXA3thyroid gland development; parathyroid gland development; cartilage development; embryonic skeletal system morphogenesis; organ formation; thymus development; specification of organ position; anterior/posterior pattern specification; positive regulation of cell proliferation; multicellular organismal development; blood vessel remodeling; angiogenesis; glossopharyngeal nerve morphogenesis
HOXA4multicellular organismal development; anatomical structure morphogenesis
HOXA5mammary gland alveolus development; lung alveolus development; embryonic skeletal system morphogenesis; bronchiole development; epithelial tube branching involved in lung morphogenesis; lung goblet cell differentiation; lung-associated mesenchyme development; trachea cartilage morphogenesis; intestinal epithelial cell maturation; mesenchymal-epithelial cell signaling; mammary gland epithelial cell differentiation; cell-cell signaling involved in mammary gland development; anterior/posterior pattern specification; negative regulation of erythrocyte differentiation; morphogenesis of an epithelium; respiratory system process; pattern specification process; positive regulation of receptor biosynthetic process; cell migration; negative regulation of angiogenesis; thyroid gland development; regulation of mammary gland epithelial cell proliferation; multicellular organism growth; positive regulation of apoptotic process; positive regulation of myeloid cell differentiation; positive regulation of transcription from R
HOXA6multicellular organismal development; anterior/posterior pattern specification; embryonic skeletal system morphogenesis
HOXA9mammary gland development; definitive hemopoiesis; embryonic skeletal system development; embryonic forelimb morphogenesis; proximal/distal pattern formation; anterior/posterior pattern specification; multicellular organismal development
HOXB1multicellular organismal development; embryonic skeletal system morphogenesis; anatomical structure formation involved in morphogenesis; positive regulation of transcription from RNA polymerase II promoter; facial nucleus development; facial nerve structural organization; rhombomere 5 development; rhombomere 4 development; anterior/posterior pattern specification; pattern specification process; regulation of transcription, DNA-dependent
HOXB2anterior/posterior pattern specification; neural nucleus development; embryonic skeletal system morphogenesis; facial nerve structural organization; rhombomere 4 development; dorsal/ventral pattern formation; blood circulation; multicellular organismal development; morphogenesis of an epithelial sheet; rhombomere 3 development
HOXB3definitive hemopoiesis; cartilage development; embryonic skeletal system morphogenesis; thyroid gland development; glossopharyngeal nerve morphogenesis; anterior/posterior pattern specification; multicellular organismal development; angiogenesis
HOXB7myeloid cell differentiation; positive regulation of branching involved in ureteric bud morphogenesis; embryonic skeletal system morphogenesis; anterior/posterior pattern specification; multicellular organismal development; regulation of transcription, DNA-dependent
HOXB8regulation of transcription, DNA-dependent; multicellular organismal development; grooming behavior; adult locomotory behavior; anterior/posterior pattern specification; sensory perception of pain; dorsal spinal cord development; embryonic skeletal system morphogenesis
HOXC11endoderm development; multicellular organismal development
HOXC9multicellular organismal development
HOXD1embryonic skeletal system development; multicellular organismal development
HOXD10forelimb morphogenesis; skeletal system development; multicellular organismal development; skeletal muscle tissue development; adult locomotory behavior; anterior/posterior pattern specification; proximal/distal pattern formation; spinal cord motor neuron cell fate specification; embryonic limb morphogenesis; hindlimb morphogenesis; positive regulation of transcription from RNA polymerase II promoter; embryonic skeletal system morphogenesis; peripheral nervous system neuron development; neuromuscular process
HOXD11regulation of transcription, DNA-dependent; cartilage development involved in endochondral bone morphogenesis; developmental growth; embryonic digit morphogenesis; positive regulation of chondrocyte differentiation; positive regulation of cell development; proximal/distal pattern formation; dorsal/ventral pattern formation; anterior/posterior pattern specification; pattern specification process; organ induction; branching involved in ureteric bud morphogenesis; metanephros development; skeletal system development
HOXD13embryonic hindgut morphogenesis; gland morphogenesis; anterior/posterior pattern specification; pattern specification process; multicellular organismal development; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; skeletal system development; regulation of branching involved in prostate gland morphogenesis; branch elongation of an epithelium; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; morphogenesis of an epithelial fold; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; regulation of cell proliferation; male genitalia development
HOXD3embryonic skeletal system morphogenesis; cartilage development; positive regulation of gene expression; positive regulation of neuron differentiation; thyroid gland development; transcription, DNA-dependent; cell-matrix adhesion; Notch signaling pathway; multicellular organismal development; anterior/posterior pattern specification
HOXD4stem cell differentiation; multicellular organismal development; anterior/posterior pattern specification; embryonic skeletal system morphogenesis; regulation of transcription, DNA-dependent
HOXD9skeletal muscle tissue development; peripheral nervous system neuron development; embryonic skeletal system morphogenesis; positive regulation of transcription from RNA polymerase II promoter; hindlimb morphogenesis; embryonic forelimb morphogenesis; mammary gland development; proximal/distal pattern formation; anterior/posterior pattern specification; adult locomotory behavior; multicellular organismal development
HP1BP3nucleosome assembly
HPDL-phenylalanine catabolic process; tyrosine catabolic process; aromatic amino acid family metabolic process; cellular nitrogen compound metabolic process; small molecule metabolic process
HPGDSlocomotory behavior; signal transduction; fatty acid biosynthetic process; prostaglandin biosynthetic process; prostaglandin metabolic process
HPNpositive regulation of hepatocyte proliferation; regulation of cell shape; positive regulation of thyroid hormone generation; pilomotor reflex; response to thyroid hormone stimulus; cochlea morphogenesis; potassium ion transmembrane transport; detection of mechanical stimulus involved in sensory perception of sound; negative regulation of epithelial cell proliferation; positive regulation by host of viral transcription; negative regulation of apoptotic process; basement membrane disassembly; positive regulation of cell growth; positive regulation of plasminogen activation; negative regulation of epithelial to mesenchymal transition; positive regulation of gene expression; proteolysis
HPS1secretion of lysosomal enzymes; organelle organization; lysosome organization; blood coagulation; visual perception; melanocyte differentiation; positive regulation of natural killer cell activation; pigmentation; eye pigmentation; response to stimulus; retina development in camera-type eye
HPS3pigmentation; organelle organization
HPS4protein stabilization; positive regulation of eye pigmentation; melanocyte differentiation; hemostasis; blood coagulation; lysosome organization; organelle organization; protein targeting
HPS5organelle organization; blood coagulation; pigmentation
HPS6blood coagulation; melanocyte differentiation; pigmentation; organelle organization
HPSEvascular wound healing; positive regulation of protein kinase B signaling cascade; cell-matrix adhesion; positive regulation of hair follicle development; regulation of hair follicle development; positive regulation of osteoblast proliferation; positive regulation of blood coagulation; positive regulation vascular endothelial growth factor production; carbohydrate metabolic process; cell adhesion; proteoglycan metabolic process
HPSE2carbohydrate metabolic process
HPXheme metabolic process; positive regulation of immunoglobulin production; positive regulation of humoral immune response mediated by circulating immunoglobulin; transport; cellular iron ion homeostasis; heme transport; hemoglobin metabolic process; positive regulation of tyrosine phosphorylation of Stat1 protein; interspecies interaction between organisms; regulation of protein metabolic process; positive regulation of interferon-gamma-mediated signaling pathway
HRprotein heterooligomerization; regulation of transcription, DNA-dependent; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription, DNA-dependent
HRAScellular senescence; positive regulation of DNA replication; MAPK cascade; activation of MAPKK activity; positive regulation of protein phosphorylation; endocytosis; apoptotic process; chemotaxis; cell cycle arrest; visual learning; positive regulation of JNK cascade; signal transduction; cell surface receptor signaling pathway; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction; Ras protein signal transduction; synaptic transmission; axon guidance; blood coagulation; positive regulation of cell proliferation; negative regulation of cell proliferation; insulin receptor signaling pathway; nerve growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; induction of apoptosis by intracellular signals; organ morphogenesis; actin cytoskeleton organization; mitotic cell cycle G1/S transition checkpoint; regulation of synaptic transmission, GABAergic; positive regulation of Rac protein signal transduction; social behavior; positive regul
HRASLS-
HRASLS5-
HRCmuscle contraction
HRH1positive regulation of vasoconstriction; positive regulation of nitric oxide biosynthetic process; negative regulation of steroid biosynthetic process; response to gravity; synaptic transmission; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; G-protein coupled receptor signaling pathway; inflammatory response
HRH2immune response; G-protein signaling, coupled to cyclic nucleotide second messenger
HRH3G-protein signaling, coupled to cyclic nucleotide second messenger; neurotransmitter secretion
HRH4inflammatory response
HRSP12regulation of translational termination
HS2ST1ureteric bud formation; heparin metabolic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
HS3ST2circadian rhythm
HS6ST3-
HSD17B11androgen catabolic process; steroid biosynthetic process
HSD17B12extracellular matrix organization; small molecule metabolic process; cellular lipid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; positive regulation of cell-substrate adhesion; steroid biosynthetic process
HSD17B13-
HSD17B14steroid catabolic process
HSD17B4sterol transport; small molecule metabolic process; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase; bile acid metabolic process; bile acid biosynthetic process; fatty acid metabolic process
HSD3B7regulation of cell growth; oxidation-reduction process; bile acid metabolic process; small molecule metabolic process; bile acid biosynthetic process; steroid biosynthetic process
HSF1embryonic process involved in female pregnancy; positive regulation of multicellular organism growth; negative regulation of tumor necrosis factor production; response to lipopolysaccharide; response to heat; negative regulation of cell proliferation; spermatogenesis; protein phosphorylation; regulation of transcription, DNA-dependent; embryonic placenta development
HSF2regulation of transcription, DNA-dependent; spermatogenesis; response to stress; transcription from RNA polymerase II promoter
HSF4positive regulation of cell proliferation; response to stress; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; histone H3-K9 demethylation; camera-type eye development; protein homotrimerization; cell development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation
HSF5-
HSP90AB1response to stress; regulation of type I interferon-mediated signaling pathway; placenta development; protein folding; response to unfolded protein; axon guidance; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; innate immune response; positive regulation of nitric oxide biosynthetic process; regulation of interferon-gamma-mediated signaling pathway
HSP90B1anti-apoptosis; response to stress; activation of signaling protein activity involved in unfolded protein response; protein transport; ER-associated protein catabolic process; endoplasmic reticulum unfolded protein response; actin rod assembly; regulation of phosphoprotein phosphatase activity; sequestering of calcium ion; cellular response to ATP; protein folding; response to hypoxia
HSPA12A-
HSPA12Bresponse to stress
HSPA14'de novo' cotranslational protein folding
HSPA2synaptonemal complex disassembly; positive regulation of protein phosphorylation; response to stress; response to unfolded protein; male meiosis; male meiosis I; spermatid development; positive regulation of cyclin-dependent protein kinase activity involved in G2/M
HSPA4Lprotein folding; response to unfolded protein; response to stress
HSPA5positive regulation of protein ubiquitination; ATP catabolic process; platelet degranulation; regulation of protein folding in endoplasmic reticulum; proteolysis involved in cellular protein catabolic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; cellular response to glucose starvation; endoplasmic reticulum unfolded protein response; negative regulation of transforming growth factor beta receptor signaling pathway; ER-associated protein catabolic process; platelet activation; cerebellar Purkinje cell layer development; cerebellum structural organization; blood coagulation; activation of signaling protein activity involved in unfolded protein response; ER overload response; anti-apoptosis
HSPA9protein folding; protein export from nucleus; anti-apoptosis
HSPG2small molecule metabolic process; cartilage development involved in endochondral bone morphogenesis; cardiac muscle tissue development; embryonic skeletal system morphogenesis; lipoprotein metabolic process; extracellular matrix organization; protein localization; brain development; lipid metabolic process; chondrocyte differentiation; endochondral ossification; angiogenesis
HSPH1response to stress; positive regulation of MHC class I biosynthetic process; chaperone mediated protein folding requiring cofactor; positive regulation of NK T cell activation; response to unfolded protein
HTR1Abehavior; regulation of feeding behavior; positive regulation of cell proliferation; serotonin receptor signaling pathway; inhibition of adenylate cyclase activity by serotonin receptor signaling pathway; G-protein coupled receptor signaling pathway
HTR1BG-protein signaling, coupled to cyclic nucleotide second messenger; response to cocaine; G-protein coupled receptor internalization; G-protein coupled receptor signaling pathway; response to drug; activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; serotonin receptor signaling pathway; synaptic transmission; response to toxin; regulation of dopamine secretion; negative regulation of cAMP biosynthetic process; negative regulation of synaptic transmission, GABAergic; drinking behavior; response to ethanol; bone remodeling; response to mineralocorticoid stimulus; negative regulation of synaptic transmission, glutamatergic; cellular response to temperature stimulus
HTR1EG-protein coupled receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor signaling pathway; synaptic transmission
HTR1Fserotonin receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission
HTR2Crelease of sequestered calcium ion into cytosol; cGMP biosynthetic process; phosphatidylinositol biosynthetic process; serotonin receptor signaling pathway; synaptic transmission; feeding behavior; response to drug; ERK1 and ERK2 cascade
HTR3Aserotonin receptor signaling pathway; transmembrane transport; ion transmembrane transport; digestion; synaptic transmission; ion transport; transport
HTR3Eion transmembrane transport; transmembrane transport
HTR4gamma-aminobutyric acid signaling pathway; positive regulation of cell proliferation; serotonin receptor signaling pathway; activation of adenylate cyclase activity by G-protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway
HTR5AG-protein coupled receptor signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor signaling pathway; brain development; cAMP-mediated signaling; hippocampus development; response to estradiol stimulus
HTRA1regulation of cell growth; negative regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; proteolysis
HTRA2proteolysis; cleavage of cytoskeletal proteins involved in apoptosis; response to stress; mitochondrion organization; cell cycle arrest; adult walking behavior; induction of apoptosis by intracellular signals; positive regulation of cell death; forebrain development; regulation of multicellular organism growth; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; neuron development; cellular response to growth factor stimulus; execution phase of apoptosis; positive regulation of intrinsic apoptotic signaling pathway; positive regulation of apoptotic process
HTRA4proteolysis; regulation of cell growth
HTTretrograde vesicle-mediated transport, Golgi to ER; establishment of mitotic spindle orientation; negative regulation of extrinsic apoptotic signaling pathway; organ development; vesicle transport along microtubule; regulation of protein phosphatase type 2A activity; cell death; Golgi organization; apoptotic process
HUNKmulticellular organismal development; signal transduction
HUWE1protein ubiquitination involved in ubiquitin-dependent protein catabolic process; cell differentiation; histone ubiquitination; protein monoubiquitination; protein modification process; protein polyubiquitination; base-excision repair
HVCN1ion transport; response to pH; response to zinc ion; proton transport; transmembrane transport
HYAL2cellular response to tumor necrosis factor; cellular response to UV-B; cellular response to transforming growth factor beta stimulus; cellular response to interleukin-1; renal water absorption; negative regulation of protein tyrosine kinase activity; negative regulation of protein kinase B signaling cascade; cartilage development; entry of virus into host cell; response to antibiotic; positive regulation of transcription from RNA polymerase II promoter; negative regulation of MAP kinase activity; positive regulation of apoptotic process; positive regulation of protein import into nucleus; positive regulation of urine volume; negative regulation of cell growth; hyaluronan catabolic process; transformation of host cell by virus; translocation of virus into host cell; response to virus; glycosaminoglycan catabolic process; carbohydrate metabolic process
HYDIN-
HYKK-
HYOU1response to hypoxia; response to stress; activation of signaling protein activity involved in unfolded protein response; endoplasmic reticulum unfolded protein response
IARStRNA aminoacylation for protein translation; isoleucyl-tRNA aminoacylation; gene expression
IARS2tRNA aminoacylation for protein translation; isoleucyl-tRNA aminoacylation; gene expression
IBSPcell adhesion; ossification; cellular response to growth factor stimulus; biomineral tissue development; extracellular matrix organization
IBTKrelease of sequestered calcium ion into cytosol; negative regulation of protein tyrosine kinase activity; negative regulation of protein phosphorylation
ICA1regulation of protein homodimerization activity; neurotransmitter transport
ICAM1positive regulation of vasoconstriction; response to ethanol; response to copper ion; virion attachment, binding of host cell surface receptor; regulation of immune response; leukocyte migration; positive regulation of NF-kappaB transcription factor activity; adhesion to symbiont; negative regulation of calcium ion transport; interferon-gamma-mediated signaling pathway; cellular response to lipopolysaccharide; cellular response to alkaloid; cellular response to glucose stimulus; cellular response to interleukin-1; cellular response to tumor necrosis factor; cellular response to hypoxia; heterophilic cell-cell adhesion; cell aging; regulation of leukocyte mediated cytotoxicity; response to amphetamine; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; T cell antigen processing and presentation; positive regulation of cellular extravasation; ovarian follicle development; positive regulation of nitric oxide biosynthetic process; cell adhesion; leukocyte
ICAM2cell-cell adhesion; regulation of immune response
ICAM5cell-cell adhesion
ICKprotein phosphorylation; signal transduction; intracellular protein kinase cascade; multicellular organismal development
ICOSimmune response; T cell costimulation
IDEinterspecies interaction between organisms; proteolysis involved in cellular protein catabolic process; protein heterooligomerization; protein homotetramerization; beta-amyloid metabolic process; negative regulation of proteolysis; hormone catabolic process; bradykinin catabolic process; sex differentiation; proteolysis; signal transduction
IDH1tricarboxylic acid cycle; small molecule metabolic process; cellular lipid metabolic process; response to oxidative stress; glutathione metabolic process; NADPH regeneration; 2-oxoglutarate metabolic process; isocitrate metabolic process; glyoxylate cycle
IDS-
IDUAlysosome organization; skeletal system morphogenesis; chemical homeostasis; limb morphogenesis; disaccharide metabolic process; cell morphogenesis; carbohydrate metabolic process
IER2-
IER5-
IFFO1-
IFI16DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; negative regulation of transcription, DNA-dependent; monocyte differentiation; myeloid cell differentiation; hemopoiesis; response to virus; cell proliferation; regulation of transcription, DNA-dependent
IFI27activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis by extracellular signals; activation of pro-apoptotic gene products; cytokine-mediated signaling pathway; type I interferon-mediated signaling pathway
IFI44response to virus
IFI44Lresponse to virus; immune response
IFIH1positive regulation of interferon-alpha production; positive regulation of interferon-beta production; regulation of apoptotic process; negative regulation of type I interferon production; interspecies interaction between organisms; detection of virus; innate immune response
IFIT1B-
IFIT5-
IFITM1cell surface receptor signaling pathway; type I interferon-mediated signaling pathway; regulation of immune response; innate immune response; cytokine-mediated signaling pathway; response to virus; response to biotic stimulus; negative regulation of cell proliferation
IFNA5blood coagulation; regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; innate immune response; cytokine-mediated signaling pathway; response to virus
IFNAR2regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; response to interferon-alpha; cytokine-mediated signaling pathway; response to virus; cell proliferation; JAK-STAT cascade; cell surface receptor signaling pathway; regulation of transcription from RNA polymerase II promoter
IFNB1cytokine-mediated signaling pathway; innate immune response; negative regulation of viral genome replication; defense response to bacterium; B cell proliferation; negative regulation of T-helper 2 cell cytokine production; negative regulation of viral transcription; natural killer cell activation; positive regulation of innate immune response; cellular response to exogenous dsRNA; regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; defense response to virus; negative regulation of virion penetration into host cell; positive regulation of transcription from RNA polymerase II promoter; negative regulation of T cell differentiation; cell surface receptor signaling pathway; regulation of MHC class I biosynthetic process; negative regulation of cell proliferation; blood coagulation; humoral immune response; activation of cysteine-type endopeptidase activity involved in apoptotic process; induction of apoptosis; adaptive immune response; response to virus
IFNEdefense response; response to virus
IFNGR1cytokine-mediated signaling pathway; signal transduction; interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; response to virus
IFNGR2interferon-gamma-mediated signaling pathway; cytokine-mediated signaling pathway; response to virus; cell surface receptor signaling pathway; regulation of interferon-gamma-mediated signaling pathway
IFNKresponse to virus; regulation of transcription, DNA-dependent; defense response; negative regulation of cell proliferation; cytokine-mediated signaling pathway; natural killer cell activation; positive regulation of innate immune response
IFNLR1-
IFNW1response to virus; defense response; cell cycle arrest
IFRD1multicellular organismal development; myoblast cell fate determination; adult somatic muscle development; muscle cell differentiation
IFT122cilium morphogenesis; embryonic heart tube development; cell projection organization; neural tube closure; camera-type eye morphogenesis; limb development; embryonic body morphogenesis; multicellular organismal development
IFT140-
IFT172smoothened signaling pathway; cilium assembly; protein processing; determination of left/right symmetry; neural tube formation; dorsal/ventral pattern formation; multicellular organismal development
IFT43cilium morphogenesis; intraflagellar retrograde transport; cell projection organization
IFT46flagellum assembly; intraflagellar transport; protein stabilization
IFT57regulation of apoptotic process; regulation of transcription, DNA-dependent; apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process
IFT74-
IGDCC3neuromuscular process controlling balance
IGDCC4-
IGF1Restablishment of cell polarity; male sex determination; positive regulation of cell migration; mammary gland development; exocrine pancreas development; neuron projection development; positive regulation of cytokinesis; response to vitamin E; negative regulation of apoptotic process; positive regulation of MAPK cascade; positive regulation of DNA replication; positive regulation of anti-apoptosis; regulation of JNK cascade; inactivation of MAPKK activity; protein autophosphorylation; insulin-like growth factor receptor signaling pathway; phosphatidylinositol-mediated signaling; protein tetramerization; protein heterooligomerization; organ morphogenesis; positive regulation of steroid hormone biosynthetic process; prostate gland epithelium morphogenesis; negative regulation of protein kinase B signaling cascade; positive regulation of protein kinase B signaling cascade; anti-apoptosis; immune response; signal transduction; axonogenesis; brain development; positive regulation of cell proliferation; insulin rece
IGF2BP2anatomical structure morphogenesis; negative regulation of translation; regulation of cytokine biosynthetic process
IGF2Rinsulin-like growth factor receptor signaling pathway; signal transduction; receptor-mediated endocytosis
IGFALSsignal transduction; cell adhesion
IGFBP2aging; signal transduction; female pregnancy; regulation of insulin-like growth factor receptor signaling pathway; response to nutrient; response to mechanical stimulus; response to lithium ion; response to estradiol stimulus; response to retinoic acid; cellular response to hormone stimulus; positive regulation of activated T cell proliferation; response to drug; response to stress; regulation of cell growth; response to glucocorticoid stimulus
IGFBPL1regulation of cell growth
IGFL3-
IGFLR1-
IGFN1-
IGHMBP2translation; regulation of transcription, DNA-dependent; DNA recombination; DNA repair; DNA replication; negative regulation of transcription from RNA polymerase II promoter; cell death; DNA duplex unwinding; protein homooligomerization
IGSF1signal transduction; regulation of transcription, DNA-dependent
IGSF10tissue regeneration; cell differentiation; multicellular organismal development; ossification
IGSF11regulation of growth; cell adhesion
IGSF21-
IGSF22-
IGSF3-
IGSF5-
IGSF8cell proliferation; cellular component movement; single fertilization; nervous system development; skeletal muscle tissue development
IKBIPresponse to X-ray; induction of apoptosis
IKBKAPI-kappaB phosphorylation; signal transduction; immune response; protein phosphorylation; protein complex assembly; transcription elongation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
IKBKEToll signaling pathway; response to DNA damage stimulus; immune response; protein phosphorylation; MyD88-independent toll-like receptor signaling pathway; innate immune response; DNA damage response, signal transduction resulting in induction of apoptosis; negative regulation of type I interferon production; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; TRIF-dependent toll-like receptor signaling pathway; NIK/NF-kappaB cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade
IKZF3regulation of B cell differentiation; regulation of transcription from RNA polymerase II promoter; mesoderm development; regulation of B cell proliferation; B cell activation; regulation of apoptotic process; regulation of lymphocyte differentiation
IL10RAsignal transduction
IL10RBimmune response; signal transduction; inflammatory response
IL12Acell cycle arrest; positive regulation of NK T cell activation; defense response to Gram-positive bacterium; positive regulation of lymphocyte proliferation; negative regulation of smooth muscle cell proliferation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of cell adhesion; defense response to protozoan; positive regulation of tyrosine phosphorylation of Stat4 protein; positive regulation of T cell proliferation; positive regulation of smooth muscle cell apoptosis; positive regulation of interferon-gamma production; positive regulation of T cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; immune response; positive regulation of natural killer cell activation; response to virus; response to UV-B; cell migration; response to lipopolysaccharide; negative regulation of interleukin-17 production
IL12RB2cell surface receptor signaling pathway; positive regulation of cell proliferation; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; response to lipopolysaccharide; positive regulation of interferon-gamma production; response to cytokine stimulus
IL13positive regulation of ion transport; response to ethanol; positive regulation of smooth muscle cell proliferation; positive regulation of protein secretion; positive regulation of macrophage activation; positive regulation of release of sequestered calcium ion into cytosol; cellular response to mechanical stimulus; cellular response to cytokine stimulus; negative regulation of transforming growth factor beta production; signal transduction; response to lipopolysaccharide; positive regulation of B cell proliferation; regulation of proton transport; cell-cell signaling; immune response; inflammatory response; cellular component movement; positive regulation of immunoglobulin production; response to nicotine
IL13RA1cell surface receptor signaling pathway
IL13RA2signal transduction; cytokine-mediated signaling pathway
IL15RAcytokine-mediated signaling pathway; positive regulation of natural killer cell differentiation; cell proliferation; signal transduction
IL16induction of positive chemotaxis; interspecies interaction between organisms; leukocyte chemotaxis; immune response; chemotaxis; regulation of transcription, DNA-dependent
IL17Acell death; fibroblast activation; cellular response to glucocorticoid stimulus; cellular response to interleukin-1; positive regulation of transcription from RNA polymerase II promoter; positive regulation of osteoclast differentiation; positive regulation of interleukin-23 production; protein glycosylation; apoptotic process; inflammatory response; immune response; cell-cell signaling
IL17Ccell-cell signaling; cell surface receptor signaling pathway; inflammatory response; neutrophil differentiation
IL17Dinflammatory response
IL17Fregulation of interleukin-6 biosynthetic process; regulation of interleukin-2 biosynthetic process; lymphotoxin A biosynthetic process; cytokine biosynthetic process; inflammatory response; proteoglycan metabolic process; negative regulation of angiogenesis; regulation of interleukin-8 biosynthetic process; regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; cartilage development; regulation of transforming growth factor beta receptor signaling pathway
IL17RAcell surface receptor signaling pathway; positive regulation of interleukin-23 production; fibroblast activation
IL17RE-
IL18R1innate immune response; signal transduction; immune response
IL18RAPcell surface receptor signaling pathway; signal transduction; immune response; innate immune response; inflammatory response
IL1Apositive regulation of cell division; fever generation; positive regulation of ERK1 and ERK2 cascade; regulation of sensory perception of pain; positive regulation of cytokine secretion; response to copper ion; positive regulation of JNK cascade; positive regulation of transcription from RNA polymerase II promoter; positive regulation of mitosis; positive regulation of angiogenesis; positive regulation of interleukin-2 biosynthetic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; wound healing; cellular response to heat; response to L-ascorbic acid; positive regulation of interleukin-6 production; response to lipopolysaccharide; cytokine-mediated signaling pathway; keratinization; response to hypoxia; apoptotic process; anti-apoptosis; inflammatory response; immune response; cell proliferation; response to ozone; response to organic nitrogen; response to gamma radiation; positive regulation vascular endothelial growth factor production; positive regulation of steroid biosynthetic process; re
IL1R2immune response
IL1RAPprotein complex assembly; inflammatory response; immune response; signal transduction; innate immune response
IL1RAPL1innate immune response; negative regulation of exocytosis; negative regulation of calcium ion transport via voltage-gated calcium channel activity; regulation of neuron projection development; signal transduction
IL1RAPL2signal transduction; central nervous system development; innate immune response
IL1RL1immune response; negative regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of macrophage activation; positive regulation of interleukin-5 production; negative regulation of interferon-gamma production; cytokine-mediated signaling pathway; innate immune response; negative regulation of T-helper 1 type immune response; signal transduction; positive regulation of inflammatory response; positive regulation of chemokine secretion
IL1RL2innate immune response; cellular defense response; signal transduction
IL20RA-
IL21positive regulation of natural killer cell cytokine production; positive regulation of tissue remodeling; positive regulation of inflammatory response; immune response; cell maturation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of interferon-gamma biosynthetic process; signal transduction; positive regulation of interleukin-10 production; positive regulation of interleukin-17 production; positive regulation of T cell proliferation; positive regulation of natural killer cell differentiation
IL21Rnatural killer cell activation
IL22inflammatory response; cell-cell signaling; acute-phase response
IL22RA1-
IL23Anegative regulation of interleukin-10 production; positive regulation of T-helper 17 cell lineage commitment; positive regulation of NF-kappaB import into nucleus; positive regulation of defense response to virus by host; positive regulation of T-helper 1 type immune response; response to virus; positive regulation of activation of JAK2 kinase activity; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interferon-gamma production; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; positive regulation of interleukin-17 production; positive regulation of tumor necrosis factor production; positive regulation of natural killer cell activation; positive regulation of natural killer cell proliferation; positive regulation of tissue remodeling; positive regulation of T cell proliferation; positive regulation of activated T cell proliferation; positive regulation of T cell mediated cytotoxicity; regulation of tyr
IL23Rpositive regulation of interleukin-17 production; positive regulation of interleukin-12 production; positive regulation of interferon-gamma production; positive regulation of granulocyte macrophage colony-stimulating factor production; negative regulation of interleukin-10 production; response to lipopolysaccharide; positive regulation of activation of JAK2 kinase activity; positive regulation of natural killer cell proliferation; response to interferon-gamma; positive regulation of T cell proliferation; positive regulation of activated T cell proliferation; defense response to Gram-negative bacterium; regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of T-helper 1 type immune response; positive regulation of defense response to virus by host; positive regulation of T cell mediated cytotoxicity; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of tyrosine phosphorylation of Stat4 protein; positive regulation of osteoclast differentiation; positiv
IL24apoptotic process
IL25inflammatory response to antigenic stimulus; response to fungus; response to nematode; eosinophil differentiation
IL27RApositive regulation of T-helper 1 type immune response; negative regulation of type 2 immune response; immune response; cell surface receptor signaling pathway; positive regulation of interferon-gamma production; regulation of isotype switching to IgG isotypes; defense response to Gram-positive bacterium
IL2RApositive regulation of activated T cell proliferation; negative regulation of immune response; negative regulation of inflammatory response; negative regulation of defense response to virus; regulation of T cell homeostatic proliferation; positive regulation of T cell differentiation; positive regulation of apoptotic process; negative regulation of T cell proliferation; cytokine-mediated signaling pathway; cell proliferation; cell surface receptor signaling pathway; immune response; activation-induced cell death of T cells; apoptotic process; inflammatory response to antigenic stimulus
IL34innate immune response; positive regulation of cell proliferation; inflammatory response; positive regulation of protein phosphorylation
IL36Bimmune response
IL37immune response
IL4positive regulation of tyrosine phosphorylation of Stat5 protein; response to drug; regulation of phosphorylation; positive regulation of activated T cell proliferation; positive regulation of T cell proliferation; type 2 immune response; T-helper 2 cell cytokine production; response to cytokine stimulus; positive regulation of interleukin-13 production; positive regulation of interleukin-10 production; positive regulation of B cell proliferation; B cell differentiation; response to organic cyclic compound; regulation of proton transport; positive regulation of cell proliferation; cholesterol metabolic process; response to nutrient; female pregnancy; cellular defense response; immune response; chemotaxis; negative regulation of chronic inflammatory response; negative regulation of acute inflammatory response; innate immune response in mucosa; negative regulation of apoptotic process; negative regulation of macrophage activation; regulation of inflammatory response; positive regulation of peptidyl-tyrosine pho
IL4I1-
IL4Rsignal transduction; production of molecular mediator involved in inflammatory response; positive regulation of chemokine secretion; positive regulation of T-helper 2 cell differentiation; negative regulation of T-helper 1 cell differentiation; response to estrogen stimulus; immune response; positive regulation of macrophage activation; regulation of cell proliferation; interleukin-4-mediated signaling pathway; ovulation
IL5RAinterleukin-5-mediated signaling pathway; cell proliferation; signal transduction
IL6cell redox homeostasis; regulation of angiogenesis; positive regulation of DNA replication; positive regulation of translation; negative regulation of gluconeogenesis; positive regulation of osteoblast differentiation; positive regulation of neuron differentiation; positive regulation of T-helper 2 cell differentiation; negative regulation of fat cell differentiation; positive regulation of nitric oxide biosynthetic process; regulation of circadian sleep/wake cycle, non-REM sleep; negative regulation of chemokine biosynthetic process; neuroprotection; positive regulation of MAPK cascade; positive regulation of B cell activation; response to amino acid stimulus; positive regulation of anti-apoptosis; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of JAK-STAT cascade; response to antibiotic; muscle cell homeostasis; bone remodeling; negative regulation of hormone secretion; negative regulation of muscle organ develop
IL6Rpositive regulation of JAK-STAT cascade; positive regulation of smooth muscle cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; positive regulation of NF-kappaB transcription factor activity; response to glucocorticoid stimulus; response to cytokine stimulus; response to cAMP; interleukin-6-mediated signaling pathway; ciliary neurotrophic factor-mediated signaling pathway; positive regulation of osteoblast differentiation; hepatic immune response; neutrophil mediated immunity; monocyte chemotaxis; positive regulation of leukocyte chemotaxis; acute-phase response; positive regulation of cell proliferation; response to gamma radiation; positive regulation of activation of Janus kinase activity; cell growth; cytokine-mediated signaling pathway; endocrine pancreas development; response to lipopolysaccharide; negative regulation of interleukin-8 production; positive regulation of chemokine producti
IL6STinterleukin-27-mediated signaling pathway; positive regulation of adaptive immune response; negative regulation of interleukin-6-mediated signaling pathway; ciliary neurotrophic factor-mediated signaling pathway; interleukin-6-mediated signaling pathway; reduction of cytosolic calcium ion concentration; leukemia inhibitory factor signaling pathway; positive regulation of anti-apoptosis; positive regulation of osteoblast differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of T cell proliferation; response to cytokine stimulus; cytokine-mediated signaling pathway; positive regulation of smooth muscle cell migration; positive regulation of cardiac muscle hypertrophy; positive regulation vascular endothelial growth factor production; positive regulation of cell proliferation; response to nutrient; positive regulation of acute inflammatory response; triglyceride mobilization; JAK-STAT cascade
ILDR1-
ILDR2cell differentiation; homeostasis of number of cells within a tissue; response to glucose stimulus; insulin secretion; pancreas development
ILF3positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; M phase
ILKcell cycle arrest; negative regulation of smooth muscle cell migration; negative regulation of protein kinase activity; protein phosphorylation; positive regulation of cell-matrix adhesion; branching involved in ureteric bud morphogenesis; regulation of cell growth; integrin-mediated signaling pathway; cell aging; cell proliferation; positive regulation of cell proliferation; regulation of signal transduction; negative regulation of cardiac muscle cell apoptosis; cell-matrix adhesion; peptidyl-serine phosphorylation; positive regulation of BMP signaling pathway; positive regulation of cell migration; positive regulation of canonical Wnt receptor signaling pathway; positive regulation of protein kinase B signaling cascade; protein heterooligomerization; positive regulation of dendrite morphogenesis; neuron projection morphogenesis; negative regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; positive regulation of axon extension; positive regulation of osteoblas
ILKAPregulation of S phase of mitotic cell cycle; protein dephosphorylation; negative regulation of cell cycle
ILVBL-
IMMP2Lovarian follicle development; ovulation; spermatogenesis; protein processing involved in protein targeting to mitochondrion; proteolysis
IMP4rRNA processing
IMPDH1purine nucleotide biosynthetic process; nucleobase-containing small molecule metabolic process; lymphocyte proliferation; small molecule metabolic process; purine ribonucleoside monophosphate biosynthetic process; GMP biosynthetic process; purine base metabolic process
IMPDH2nucleobase-containing small molecule metabolic process; lymphocyte proliferation; small molecule metabolic process; GMP biosynthetic process; purine ribonucleoside monophosphate biosynthetic process; purine base metabolic process; purine nucleotide biosynthetic process
IMPG1visual perception
IMPG2visual perception
INADLcell junction assembly; intracellular signal transduction; cell-cell junction organization; tight junction assembly
INF2cellular component organization; actin cytoskeleton organization
ING1regulation of cell death; positive regulation of transcription, DNA-dependent; negative regulation of cell growth; negative regulation of cell proliferation; cell cycle; protein import into nucleus
ING2regulation of response to DNA damage stimulus; regulation of cellular senescence; seminiferous tubule development; male germ-line stem cell division; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; regulation of growth; sperm motility; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of transcription, DNA-dependent; male meiosis I; signal transduction; spermatogenesis; spermatid development; chromatin modification
ING4negative regulation of cell proliferation; histone H3 acetylation; histone H4-K5 acetylation; positive regulation of apoptotic process; histone H4-K8 acetylation; histone H4-K12 acetylation; DNA replication; histone H4-K16 acetylation; negative regulation of transcription, DNA-dependent; negative regulation of growth; cell cycle arrest; cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; apoptotic process; protein acetylation; chromatin modification
ING5negative regulation of growth; negative regulation of cell proliferation; protein acetylation; chromatin modification; positive regulation of transcription, DNA-dependent; DNA replication; histone H3 acetylation
INHAnegative regulation of macrophage differentiation; negative regulation of B cell differentiation; negative regulation of interferon-gamma biosynthetic process; hemoglobin biosynthetic process; negative regulation of phosphorylation; regulation of cell proliferation; erythrocyte differentiation; cell differentiation; response to external stimulus; male gonad development; nervous system development; cell-cell signaling; cell surface receptor signaling pathway; signal transduction; cell cycle arrest; induction of apoptosis; ovarian follicle development; skeletal system development; positive regulation of follicle-stimulating hormone secretion; negative regulation of cell cycle; regulation of cell cycle; negative regulation of follicle-stimulating hormone secretion
INHBAhemoglobin biosynthetic process; G1/S transition of mitotic cell cycle; progesterone secretion; negative regulation of interferon-gamma biosynthetic process; negative regulation of B cell differentiation; positive regulation of erythrocyte differentiation; negative regulation of macrophage differentiation; negative regulation of cell cycle; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; regulation of follicle-stimulating hormone secretion; positive regulation of follicle-stimulating hormone secretion; negative regulation of follicle-stimulating hormone secretion; mesodermal cell differentiation; palate development; positive regulation of ovulation; eyelid development in camera-type eye; cellular response to follicle-stimulating hormone stimulus; cellular response to cholesterol; negative regulation of phosphorylation; ovarian follicle development; hair follicle development; hemopoietic progenitor cell differentiation; regulation of tr
INHBEgrowth
INO80cell division; spindle assembly; UV-damage excision repair; cellular response to UV; positive regulation of transcription from RNA polymerase II promoter; DNA duplex unwinding; positive regulation of cell growth; positive regulation of DNA replication involved in S phase; cell cycle; chromatin remodeling; DNA recombination; cellular response to ionizing radiation; regulation of G1/S transition of mitotic cell cycle; double-strand break repair; ATP catabolic process; double-strand break repair via homologous recombination; mitotic sister chromatid segregation
INO80Bregulation of transcription, DNA-dependent; DNA recombination; DNA repair
INPP4Bphosphatidylinositol-3-phosphate biosynthetic process; signal transduction
INPP5Acell communication; phosphatidylinositol phosphorylation
INPP5Bsignal transduction; regulation of small GTPase mediated signal transduction; phosphatidylinositol dephosphorylation; phosphatidylinositol phosphorylation; small GTPase mediated signal transduction
INPP5Edephosphorylation; phosphatidylinositol phosphorylation; positive regulation of neuron projection development; lipid metabolic process
INPP5F-
INPPL1negative regulation of platelet-derived growth factor receptor signaling pathway; negative regulation of neuron projection development; negative regulation of insulin receptor signaling pathway; response to insulin stimulus; inositol trisphosphate metabolic process; response to drug; negative regulation of MAP kinase activity; negative regulation of insulin-like growth factor receptor signaling pathway; phosphatidylinositol phosphorylation; cellular lipid metabolic process; glucose metabolic process; endocytosis; actin filament organization; cell adhesion; brain development; negative regulation of DNA replication; negative regulation of cell proliferation; post-embryonic development; negative regulation of gene expression
INSCestablishment of mitotic spindle orientation; multicellular organismal development; lung epithelial cell differentiation; cell differentiation; nervous system development
INSM2regulation of transcription, DNA-dependent
INSRG-protein coupled receptor signaling pathway; glucose homeostasis; positive regulation of phosphorylation; activation of MAPK activity; negative regulation of protein phosphorylation; positive regulation of protein phosphorylation; heart morphogenesis; carbohydrate metabolic process; regulation of transcription, DNA-dependent; positive regulation of MAPK cascade; positive regulation of glucose import; regulation of embryonic development; positive regulation of cell proliferation; positive regulation of mitosis; positive regulation of glycolysis; positive regulation of DNA replication; positive regulation of glycogen biosynthetic process; response to ethanol; fat cell differentiation; positive regulation of nitric oxide biosynthetic process; protein autophosphorylation; signal transduction by phosphorylation; transformation of host cell by virus; peptidyl-tyrosine phosphorylation; response to activity; negative regulation of gene expression; positive regulation of glycoprotein biosynthetic process; regulation
INSRRcellular response to alkalinity; protein autophosphorylation; actin cytoskeleton reorganization; male sex determination; transmembrane receptor protein tyrosine kinase signaling pathway
INTS10snRNA processing
INTS5snRNA processing
INTS6snRNA processing
INTS7DNA damage checkpoint; snRNA processing; cellular response to ionizing radiation
INTUlimb development; cilium assembly; regulation of smoothened signaling pathway; nervous system development
INVSkidney development; embryonic heart tube left/right pattern formation; post-embryonic development; negative regulation of canonical Wnt receptor signaling pathway; pancreas development; Wnt receptor signaling pathway
IP6K1phosphatidylinositol phosphorylation
IP6K2positive regulation of apoptotic process; negative regulation of cell growth; cytokine-mediated signaling pathway; phosphatidylinositol phosphorylation; type I interferon-mediated signaling pathway
IP6K3protein phosphorylation; inositol phosphate biosynthetic process; phosphatidylinositol metabolic process
IPCEF1response to oxidative stress; oxygen transport; positive regulation of GTP catabolic process
IPO11intracellular protein transport
IPO13protein import into nucleus; intracellular protein transport
IPO4protein transport; intracellular protein transport
IPO5interspecies interaction between organisms; NLS-bearing substrate import into nucleus; ribosomal protein import into nucleus; intracellular protein transport
IPO7intracellular protein transport; transport; protein import into nucleus; signal transduction; interspecies interaction between organisms
IPO8signal transduction; intracellular protein transport
IPO9protein import into nucleus; intracellular protein transport; protein transport
IPP-
IPPKinositol phosphorylation
IQCB1maintenance of organ identity; photoreceptor cell maintenance; cilium assembly
IQCC-
IQCD-
IQCE-
IQCG-
IQCH-
IQGAP1small molecule metabolic process; regulation of insulin secretion; regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity; signal transduction; energy reserve metabolic process; glomerular visceral epithelial cell development
IQGAP2signal transduction; regulation of small GTPase mediated signal transduction
IQGAP3Ras protein signal transduction; positive regulation of protein phosphorylation; activation of MAPK activity; negative regulation of gene expression; signal transduction; positive regulation of mammary gland epithelial cell proliferation; G1/S transition of mitotic cell cycle; regulation of small GTPase mediated signal transduction; ERK1 and ERK2 cascade; cellular response to organic substance; positive regulation of gene expression; regulation of cell size
IQSEC1regulation of ARF protein signal transduction
IQSEC3regulation of ARF protein signal transduction
IQUB-
IRAK1NIK/NF-kappaB cascade; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; protein phosphorylation; anti-apoptosis; JNK cascade; signal transduction; transmembrane receptor protein serine/threonine kinase signaling pathway; protein autophosphorylation; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; innate immune response; positive regulation of JUN kinase activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of NF-kappaB transcription factor activity; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; Toll signaling pathway; protein ubiquitination; lipopolysaccharide-mediated signaling pathway; activation of NF-kappaB-inducing kinase activity; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like rec
IRAK2activation of MAPK activity; regulation of cytokine-mediated signaling pathway; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; protein phosphorylation; inflammatory response; JNK cascade; signal transduction; Toll signaling pathway; response to interleukin-1; interleukin-1-mediated signaling pathway; nucleotide-binding oligomerization domain containing signaling pathway; stress-activated MAPK cascade; positive regulation of NF-kappaB transcription factor activity; innate immune response; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; negative regulation of NF-kappaB transcription factor activity; lipopolysaccharide-mediated signaling pathway; I-kappaB kinase/NF-k
IRAK3negative regulation of protein complex disassembly; negative regulation of interleukin-6 production; response to exogenous dsRNA; regulation of protein complex disassembly; protein phosphorylation; signal transduction; response to virus; positive regulation of macrophage tolerance induction; negative regulation of macrophage cytokine production; negative regulation of protein catabolic process; cytokine-mediated signaling pathway; negative regulation of NF-kappaB transcription factor activity; response to peptidoglycan; negative regulation of toll-like receptor signaling pathway; negative regulation of tumor necrosis factor production; response to lipopolysaccharide; negative regulation of interleukin-12 production; negative regulation of cytokine-mediated signaling pathway; response to interleukin-1; interleukin-1-mediated signaling pathway; MyD88-dependent toll-like receptor signaling pathway; positive regulation of NF-kappaB transcription factor activity; protein autophosphorylation; negative regulation of
IRAK4positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; innate immune response; signal transduction; Toll signaling pathway; cytokine-mediated signaling pathway; toll-like receptor 1 signaling pathway; JNK cascade; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; cytokine production; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; protein phosphorylation
IREB2osteoclast differentiation; intestinal absorption; erythrocyte homeostasis; regulation of gene expression; post-embryonic development; metabolic process; cellular iron ion homeostasis; iron ion transport; protoporphyrinogen IX biosynthetic process; regulation of translation
IRF1type I interferon-mediated signaling pathway; transcription from RNA polymerase II promoter; cellular response to peptide hormone stimulus; cellular response to dsRNA; cellular response to tumor necrosis factor; cellular response to interleukin-1; cellular response to retinoic acid; cellular response to mechanical stimulus; response to growth hormone stimulus; interferon-gamma-mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; CD8-positive, alpha-beta T cell differentiation; negative regulation of tyrosine phosphorylation of Stat1 protein; cytokine-mediated signaling pathway; positive regulation of cell death; response to heat; blood coagulation; female pregnancy; I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-12 biosynthetic process
IRF2BP1regulation of transcription, DNA-dependent
IRF2BP2regulation of transcription, DNA-dependent
IRF2BPL-
IRF3response to exogenous dsRNA; negative regulation of transcription from RNA polymerase II promoter; MyD88-independent toll-like receptor signaling pathway; transcription from RNA polymerase II promoter; Toll signaling pathway; response to virus; response to bacterium; cytokine-mediated signaling pathway; lipopolysaccharide-mediated signaling pathway; response to lipopolysaccharide; negative regulation of type I interferon production; cellular response to dsRNA; type I interferon-mediated signaling pathway; interferon-gamma-mediated signaling pathway; positive regulation of cytokine secretion; negative regulation of defense response to virus by host; negative regulation of interferon-beta biosynthetic process; type I interferon biosynthetic process; innate immune response; interspecies interaction between organisms; positive regulation of I-kappaB kinase/NF-kappaB cascade; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway
IRF6mammary gland epithelial cell differentiation; cell cycle arrest; type I interferon-mediated signaling pathway; interferon-gamma-mediated signaling pathway; cell development; positive regulation of transcription, DNA-dependent; keratinocyte proliferation; skin development; keratinocyte differentiation; cytokine-mediated signaling pathway; negative regulation of cell proliferation
IRF9regulation of transcription, DNA-dependent; type I interferon-mediated signaling pathway; interferon-gamma-mediated signaling pathway; type I interferon biosynthetic process; cytokine-mediated signaling pathway; response to virus; cell surface receptor signaling pathway; transcription from RNA polymerase II promoter
IRS1cellular response to insulin stimulus; positive regulation of phosphorylation; protein localization to nucleus; response to insulin stimulus; positive regulation of fatty acid beta-oxidation; mammary gland development; positive regulation of cell migration; lipid catabolic process; phosphatidylinositol 3-kinase cascade; positive regulation of glucose metabolic process; regulation of gene expression; insulin receptor signaling pathway; positive regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; positive regulation of mesenchymal cell proliferation; negative regulation of insulin receptor signaling pathway; glucose homeostasis; response to peptide hormone stimulus; protein kinase B signaling cascade; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of glycogen biosynthetic process; positive regulation of glucose import; negative regulation of somatostatin secretion; positive regulation of glucagon secretion;
IRS2regulation of lipid metabolic process; JAK-STAT cascade involved in growth hormone signaling pathway; positive regulation of cell migration; lipid homeostasis; phosphatidylinositol-mediated signaling; nerve growth factor receptor signaling pathway; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; negative regulation of kinase activity; cellular response to insulin stimulus; positive regulation of insulin secretion; positive regulation of fatty acid beta-oxidation; positive regulation of B cell proliferation; mammary gland development; negative regulation of plasma membrane long-chain fatty acid transport; positive regulation of mesenchymal cell proliferation; negative regulation of B cell apoptosis; glucose metabolic process; signal transduction; brain development; positive regulation of cell proliferation; positive regulation of glucose metabolic process; insulin receptor signaling pathway; response to glucose stimulus
IRS4signal transduction
IRX6-
ISG15response to virus; cell-cell signaling; innate immune response; cytokine-mediated signaling pathway; modification-dependent protein catabolic process; ISG15-protein conjugation; type I interferon-mediated signaling pathway; interspecies interaction between organisms; negative regulation of type I interferon production
ISG20L2ribosome biogenesis
ISL1pancreas development; axon regeneration; pituitary gland development; trigeminal nerve development; visceral motor neuron differentiation; spinal cord motor neuron differentiation; spinal cord motor neuron cell fate specification; positive regulation of cell proliferation; multicellular organismal development; regulation of secondary heart field cardioblast proliferation; cardiac right ventricle morphogenesis; endocardial cushion morphogenesis; outflow tract morphogenesis; outflow tract septum morphogenesis; secondary heart field specification; neural crest cell migration; negative regulation of transcription from RNA polymerase II promoter; retinal ganglion cell axon guidance; negative regulation of neuron differentiation; positive regulation of transcription from RNA polymerase II promoter; neuron fate specification; mesenchymal cell differentiation; sensory system development; peripheral nervous system neuron axonogenesis; ventricular cardiac muscle tissue morphogenesis; pharyngeal system development; card
ISL2multicellular organismal development; neuron development; peripheral nervous system neuron development
ISLR2multicellular organismal development; positive regulation of axon extension; nervous system development
ISM2-
ISX-
ISYNA1phospholipid biosynthetic process; inositol biosynthetic process
ITCHprotein K48-linked ubiquitination; regulation of cell growth; protein modification process; ubiquitin-dependent protein catabolic process; inflammatory response; response to virus; protein ubiquitination; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production; protein K29-linked ubiquitination; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of apoptotic process; interspecies interaction between organisms; innate immune response; negative regulation of JNK cascade; entry of virus into host cell; negative regulation of defense response to virus; nucleotide-binding oligomerization domain containing signaling pathway; protein K63-linked ubiquitination; regulation of protein deubiquitination
ITGA1muscle contraction; cell chemotaxis; neuron projection morphogenesis; cellular extravasation; positive regulation of neuron apoptosis; vasodilation; neutrophil chemotaxis; axon guidance; integrin-mediated signaling pathway; cell-matrix adhesion; activation of MAPK activity; cell adhesion
ITGA10cell-matrix adhesion; integrin-mediated signaling pathway; cell adhesion
ITGA2interspecies interaction between organisms; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; axon guidance; blood coagulation; organ morphogenesis
ITGA2Bcell-matrix adhesion; platelet activation; blood coagulation; axon guidance; integrin-mediated signaling pathway; cell adhesion; platelet degranulation
ITGA4leukocyte cell-cell adhesion; chorio-allantoic fusion; face development; leukocyte migration; regulation of immune response; B cell differentiation; blood coagulation; heart development; integrin-mediated signaling pathway; heterophilic cell-cell adhesion; cell adhesion; blood vessel remodeling
ITGA5heterophilic cell-cell adhesion; angiogenesis; cell-substrate junction assembly; cell adhesion; leukocyte cell-cell adhesion; integrin-mediated signaling pathway; axon guidance; blood coagulation; memory; positive regulation of vascular endothelial growth factor receptor signaling pathway; cell-cell adhesion mediated by integrin; wound healing, spreading of epidermal cells; interspecies interaction between organisms; positive regulation of peptidyl-tyrosine phosphorylation; leukocyte migration
ITGA6hemidesmosome assembly; cell junction assembly; positive regulation of phosphorylation; positive regulation of apoptotic process; negative regulation of apoptotic process; positive regulation of transcription from RNA polymerase II promoter; leukocyte migration; blood coagulation; integrin-mediated signaling pathway; cell adhesion; cell-substrate junction assembly
ITGA7cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; muscle organ development; regulation of cell shape
ITGA8cell-matrix adhesion; metanephros development; memory; nervous system development; multicellular organismal development; inner ear morphogenesis; positive regulation of transforming growth factor beta receptor signaling pathway; extracellular matrix organization; cell differentiation; cell projection organization; cell-cell adhesion; integrin-mediated signaling pathway
ITGA9axon guidance; cell adhesion; wound healing; integrin-mediated signaling pathway
ITGADcell-cell adhesion; immune response; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; activated T cell proliferation
ITGAEintegrin-mediated signaling pathway; cell adhesion
ITGALleukocyte migration; cell adhesion; positive regulation of calcium-mediated signaling; activated T cell proliferation; regulation of immune response; positive regulation of T cell proliferation; positive regulation of cell-cell adhesion; blood coagulation; integrin-mediated signaling pathway; signal transduction; leukocyte cell-cell adhesion; heterophilic cell-cell adhesion; inflammatory response; cellular component movement; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
ITGAVleukocyte migration; regulation of phagocytosis; interspecies interaction between organisms; negative regulation of low-density lipoprotein particle receptor biosynthetic process; positive regulation of cell adhesion; entry of virus into host cell; negative regulation of lipoprotein metabolic process; entry of symbiont into host cell by promotion of host phagocytosis; positive regulation of cell proliferation; negative regulation of apoptotic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; entry of bacterium into host cell; positive regulation of osteoblast proliferation; negative regulation of lipid transport; positive regulation of cell migration; negative regulation of lipid storage; negative regulation of macrophage derived foam cell differentiation; angiogenesis; blood coagulation; axon guidance; integrin-mediated signaling pathway; cell-matrix adhesion; cell adhesion; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependen
ITGAXcell adhesion; integrin-mediated signaling pathway; blood coagulation; organ morphogenesis; leukocyte migration; defense response to virus
ITGB2neutrophil chemotaxis; leukocyte migration; regulation of immune response; regulation of peptidyl-tyrosine phosphorylation; regulation of cell shape; blood coagulation; multicellular organismal development; integrin-mediated signaling pathway; cell-matrix adhesion; leukocyte cell-cell adhesion; cell-cell signaling; cell adhesion; inflammatory response; apoptotic process
ITGB5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; muscle contraction; antigen processing and presentation of peptide antigen via MHC class I; cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; multicellular organismal development; antigen processing and presentation of exogenous peptide antigen via MHC class I
ITGB6integrin-mediated signaling pathway; inflammatory response; cell adhesion; cell-matrix adhesion; multicellular organismal development; interspecies interaction between organisms
ITGB7cell adhesion; cell-matrix adhesion; integrin-mediated signaling pathway; multicellular organismal development; regulation of immune response
ITGB8cell-matrix adhesion; multicellular organismal development; placenta blood vessel development; ganglioside metabolic process; cell adhesion; integrin-mediated signaling pathway
ITGBL1integrin-mediated signaling pathway; cell-matrix adhesion; cell adhesion
ITIH1hyaluronan metabolic process; leukocyte activation
ITIH2negative regulation of endopeptidase activity; hyaluronan metabolic process
ITIH4negative regulation of endopeptidase activity; acute-phase response; hyaluronan metabolic process
ITIH5hyaluronan metabolic process
ITIH6hyaluronan metabolic process
ITM2Bapoptotic process; induction of apoptosis; nervous system development
ITPAmetabolic process; nucleotide metabolic process
ITPKBpositive regulation of alpha-beta T cell differentiation; positive regulation of Ras protein signal transduction; positive thymic T cell selection; T cell differentiation; cell surface receptor signaling pathway; signal transduction; MAPK cascade
ITPKC-
ITPR2nerve growth factor receptor signaling pathway; response to hypoxia; cellular response to cAMP; calcium ion transmembrane transport; transmembrane transport; regulation of insulin secretion; inositol phosphate-mediated signaling; small molecule metabolic process; platelet activation; fibroblast growth factor receptor signaling pathway; blood coagulation; activation of phospholipase C activity; epidermal growth factor receptor signaling pathway; signal transduction; ion transport; transport; energy reserve metabolic process
ITPR3activation of phospholipase C activity; energy reserve metabolic process; ion transport; signal transduction; epidermal growth factor receptor signaling pathway; G-protein coupled receptor signaling pathway; elevation of cytosolic calcium ion concentration; calcium ion transport into cytosol; transmembrane transport; response to calcium ion; protein heterooligomerization; protein homooligomerization; sensory perception of umami taste; sensory perception of sweet taste; sensory perception of bitter taste; regulation of insulin secretion; inositol phosphate-mediated signaling; nerve growth factor receptor signaling pathway; small molecule metabolic process; platelet activation; fibroblast growth factor receptor signaling pathway; blood coagulation
ITPRIPL1-
ITPRIPL2-
ITSN1regulation of small GTPase mediated signal transduction; positive regulation of protein kinase B signaling cascade; synaptic vesicle endocytosis; apoptotic process; nerve growth factor receptor signaling pathway; negative regulation of neuron apoptosis; positive regulation of catalytic activity; regulation of Rho protein signal transduction; induction of apoptosis by extracellular signals; small GTPase mediated signal transduction
ITSN2endocytosis; regulation of Rho protein signal transduction
IVNS1ABPtranscription from RNA polymerase III promoter; RNA splicing; response to virus; interspecies interaction between organisms
IZUMO1cell adhesion; fusion of sperm to egg plasma membrane
IZUMO2-
JADE1regulation of transcription, DNA-dependent; histone H4-K16 acetylation; apoptotic process; response to stress; negative regulation of cell growth; histone H3 acetylation; histone H4-K5 acetylation; histone H4-K12 acetylation; histone H4-K8 acetylation
JADE3histone H4-K16 acetylation; histone H4-K12 acetylation; histone H4-K8 acetylation; histone H3 acetylation; histone H4-K5 acetylation
JAG2regulation of apoptotic process; thymic T cell selection; odontogenesis of dentin-containing tooth; regulation of cell proliferation; regulation of cell migration; T cell differentiation; regulation of cell adhesion; cell differentiation; morphogenesis of embryonic epithelium; auditory receptor cell fate commitment; multicellular organismal development; Notch receptor processing; Notch signaling pathway; cell communication; cell cycle; respiratory system process; in utero embryonic development; skeletal system development; spermatogenesis
JAK1cytokine-mediated signaling pathway; regulation of type I interferon-mediated signaling pathway; type I interferon-mediated signaling pathway; regulation of interferon-gamma-mediated signaling pathway; interferon-gamma-mediated signaling pathway; response to antibiotic; intracellular signal transduction; peptidyl-tyrosine phosphorylation; intracellular protein kinase cascade; enzyme linked receptor protein signaling pathway; protein phosphorylation
JAK2positive regulation of phosphatidylinositol 3-kinase cascade; protein phosphorylation; apoptotic process; cellular component movement; signal transduction; enzyme linked receptor protein signaling pathway; intracellular protein kinase cascade; JAK-STAT cascade; positive regulation of tumor necrosis factor production; positive regulation of apoptotic process; activation of JAK2 kinase activity; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of tyrosine phosphorylation of Stat3 protein; interleukin-12-mediated signaling pathway; intracellular signal transduction; histone H3-Y41 phosphorylation; response to tumor necrosis factor; tumor necrosis factor-mediated signaling pathway; STAT protein import into nucleus; response to lipopolysaccharide; erythrocyte differentiation; cell differentiation; actin filament polymerization; cytokine-mediated signaling pathway; peptidyl-tyrosine phosphorylation; chromatin modification; positive regulation of cell-substrate adhesion; innate i
JAK3peptidyl-tyrosine phosphorylation; negative regulation of thymocyte apoptosis; positive regulation of activated T cell proliferation; tyrosine phosphorylation of Stat5 protein; regulation of apoptotic process; T cell homeostasis; innate immune response; negative regulation of FasL biosynthetic process; negative regulation of T-helper 1 cell differentiation; positive regulation of anti-apoptosis; positive regulation of transcription from RNA polymerase II promoter; protein autophosphorylation; positive regulation of immune response; negative regulation of T cell activation; positive regulation of calcium ion transport; JAK-STAT cascade involved in growth hormone signaling pathway; regulation of T cell apoptosis; response to interleukin-2; response to interleukin-4; response to interleukin-15; response to interleukin-9; negative regulation of interleukin-12 production; negative regulation of interleukin-10 production; B cell differentiation; cytokine-mediated signaling pathway; STAT protein import into nucleus;
JAKMIP1protein transport
JAKMIP2-
JAM3angiogenesis; cell adhesion; blood coagulation; leukocyte migration; regulation of neutrophil chemotaxis
JARID2stem cell differentiation; negative regulation of transcription from RNA polymerase II promoter; liver development; multicellular organismal development; central nervous system development; negative regulation of cell proliferation; chromatin modification; negative regulation of histone methylation; negative regulation of transcription, DNA-dependent; spleen development; thymus development; positive regulation of histone H3-K9 methylation
JCHAINimmune response
JMJD1Cchromatin modification; blood coagulation; regulation of transcription, DNA-dependent
JMYpositive regulation of apoptotic process; positive regulation of sequence-specific DNA binding transcription factor activity; 'de novo' actin filament nucleation; Arp2/3 complex-mediated actin nucleation; cell cycle arrest; regulation of transcription from RNA polymerase II promoter; DNA repair; actin polymerization-dependent cell motility; induction of apoptosis
JOSD2protein deubiquitination; proteolysis
JPH1muscle organ development; regulation of ryanodine-sensitive calcium-release channel activity; calcium ion transport into cytosol
JPH2regulation of cardiac muscle tissue development; calcium ion homeostasis; positive regulation of ryanodine-sensitive calcium-release channel activity; calcium ion transport into cytosol; regulation of ryanodine-sensitive calcium-release channel activity
JPH3memory; exploration behavior; locomotion; regulation of neuronal synaptic plasticity; calcium ion transport into cytosol; regulation of ryanodine-sensitive calcium-release channel activity
JPH4regulation of ryanodine-sensitive calcium-release channel activity; calcium ion transport into cytosol
JRKLregulation of transcription, DNA-dependent; central nervous system development
JTBregulation of cell proliferation; cell cycle cytokinesis; mitosis; cell cycle; negative regulation of apoptotic process; cell division; positive regulation of protein kinase activity
JUNBresponse to peptide hormone stimulus; positive regulation of cell differentiation; response to drug; response to cytokine stimulus; osteoblast proliferation; cellular response to hormone stimulus; response to progesterone stimulus; osteoclast differentiation; response to organic cyclic compound; cellular process; response to mechanical stimulus; response to light stimulus; regulation of transcription from RNA polymerase II promoter; trophectodermal cell differentiation; in utero embryonic development; osteoblast differentiation; vasculogenesis; positive regulation of transcription from RNA polymerase II promoter during mitosis; cellular response to calcium ion; labyrinthine layer blood vessel development; embryonic process involved in female pregnancy; regulation of cell cycle; response to cAMP; response to corticosterone stimulus; decidualization
JUPatrioventricular valve morphogenesis; negative regulation of Wnt receptor signaling pathway involved in heart development; cell-cell adhesion; cytoskeletal anchoring at plasma membrane; negative regulation of heart induction by canonical Wnt receptor signaling pathway; desmosome assembly; cell morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell migration; ectoderm development; cell junction assembly; adherens junction organization; positive regulation of protein import into nucleus; skin development; cell-cell junction organization; oocyte development; detection of mechanical stimulus; positive regulation of sequence-specific DNA binding transcription factor activity; endothelial cell-cell adhesion; cellular response to indole-3-methanol; positive regulation of canonical Wnt receptor signaling pathway; morphogenesis of embryonic epithelium; nervous system development; gastrulation
KALRNsignal transduction; apoptotic process; protein phosphorylation; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; intracellular signal transduction; induction of apoptosis by extracellular signals; nervous system development; small GTPase mediated signal transduction; vesicle-mediated transport; nerve growth factor receptor signaling pathway
KANK1negative regulation of actin filament polymerization
KANK2-
KANK3-
KANK4-
KANSL1L-
KARSgene expression; interspecies interaction between organisms; tRNA processing; lysyl-tRNA aminoacylation; tRNA aminoacylation for protein translation
KAT2Amidbrain development; neural tube closure; somitogenesis; in utero embryonic development; interspecies interaction between organisms; chromatin remodeling; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; nervous system development; cell proliferation; histone deubiquitination; telencephalon development; metencephalon development; multicellular organism growth; regulation of apoptotic process; histone H3 acetylation; histone H3-K14 acetylation
KAT2Bpositive regulation of transcription from RNA polymerase II promoter; chromatin remodeling; transcription from RNA polymerase I promoter; transcription initiation from RNA polymerase I promoter; protein acetylation; negative regulation of cyclin-dependent protein kinase activity; interspecies interaction between organisms; histone H3 acetylation; negative regulation of phosphorylation; cellular response to insulin stimulus; peptidyl-lysine acetylation; N-terminal peptidyl-lysine acetylation; gene expression; negative regulation of cell proliferation; Notch signaling pathway; cell cycle arrest; cell cycle
KAT5DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; positive regulation of transcription, DNA-dependent; chromatin modification; negative regulation of transcription, DNA-dependent; interspecies interaction between organisms; regulation of growth; histone acetylation; androgen receptor signaling pathway; negative regulation of interleukin-2 production; double-strand break repair; negative regulation of transcription from RNA polymerase II promoter
KAT6Apositive regulation of transcription, DNA-dependent; myeloid cell differentiation; histone H3 acetylation; histone acetylation; chromatin modification; nucleosome assembly; negative regulation of transcription, DNA-dependent; DNA packaging
KAT6Bregulation of transcription, DNA-dependent; histone acetylation; nucleosome assembly; chromatin modification; histone H3 acetylation; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent
KAT7chromatin modification; histone H4-K16 acetylation; histone H4-K12 acetylation; histone H4-K8 acetylation; histone H4-K5 acetylation; histone H3 acetylation; regulation of transcription, DNA-dependent; DNA replication
KATNA1microtubule severing; cell cycle; mitosis; neuron migration; protein localization; negative regulation of neuron projection development; interphase of mitotic cell cycle; cell division; cytoplasmic microtubule organization
KATNAL1-
KATNAL2-
KAZNkeratinization
KBTBD2-
KBTBD3-
KBTBD4-
KBTBD6-
KCNA1ion transport; potassium ion transport; synaptic transmission; transmembrane transport; potassium ion transmembrane transport
KCNA10transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNA2potassium ion transmembrane transport; synaptic transmission; ion transport; transmembrane transport; potassium ion transport
KCNA3transmembrane transport; regulation of ion transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNA4transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNA5response to hypoxia; ion transport; potassium ion transport; synaptic transmission; potassium ion homeostasis; transmembrane transport; reduction of cytosolic calcium ion concentration; negative regulation of potassium ion transport; protein oligomerization; regulation of membrane potential
KCNA7transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNAB1transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNAB2ion transport; synaptic transmission; potassium ion transport; transmembrane transport
KCNAB3potassium ion transport; ion transport; transmembrane transport; synaptic transmission
KCNB1energy reserve metabolic process; ion transport; potassium ion transport; synaptic transmission; small molecule metabolic process; regulation of insulin secretion; transmembrane transport
KCNB2ion transport; transmembrane transport; synaptic transmission; regulation of smooth muscle contraction; potassium ion transport
KCNC2regulation of insulin secretion; transmembrane transport; small molecule metabolic process; synaptic transmission; potassium ion transport; ion transport; energy reserve metabolic process
KCNC4synaptic transmission; ion transport; potassium ion transmembrane transport; transmembrane transport; regulation of neurotransmitter secretion; potassium ion transport
KCND1synaptic transmission; transmembrane transport; potassium ion transport; ion transport
KCND2transmembrane transport; protein heterooligomerization; synaptic transmission; potassium ion transport; ion transport; regulation of action potential
KCND3transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNE1potassium ion transport; potassium ion export; regulation of heart contraction; blood circulation; sensory perception of sound; muscle contraction; ion transport; epithelial cell maturation; membrane depolarization
KCNE4potassium ion transport; ion transport
KCNG2transmembrane transport; regulation of insulin secretion; small molecule metabolic process; regulation of heart contraction; synaptic transmission; potassium ion transport; ion transport; energy reserve metabolic process
KCNG3ion transport; potassium ion transport; synaptic transmission; transmembrane transport
KCNG4synaptic transmission; potassium ion transport; ion transport; transmembrane transport
KCNH1transmembrane transport; myoblast fusion; potassium ion transport; ion transport; regulation of transcription, DNA-dependent
KCNH2regulation of membrane potential; protein heterooligomerization; transmembrane transport; blood circulation; regulation of transcription, DNA-dependent; ion transport; potassium ion transport; muscle contraction; synaptic transmission; regulation of heart contraction
KCNH3synaptic transmission; transmembrane transport; regulation of transcription, DNA-dependent; ion transport; potassium ion transport
KCNH4ion transport; transmembrane transport; synaptic transmission; potassium ion transport; regulation of transcription, DNA-dependent
KCNH5transmembrane transport; synaptic transmission; regulation of transcription, DNA-dependent; potassium ion transport; ion transport
KCNH6transmembrane transport; protein heterooligomerization; synaptic transmission; signal transduction; potassium ion transport; ion transport; regulation of transcription, DNA-dependent
KCNH7synaptic transmission; regulation of transcription, DNA-dependent; ion transport; transmembrane transport; protein heterooligomerization; circadian rhythm; potassium ion transport
KCNH8negative regulation of apoptotic process; transmembrane transport; regulation of transcription, DNA-dependent; synaptic transmission; ion transport; potassium ion transport
KCNIP3negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; response to pain; regulation of neuron apoptosis; sensory perception of pain; behavior; signal transduction; apoptotic process; potassium ion transport; ion transport
KCNIP4potassium ion transport; ion transport
KCNJ1excretion; synaptic transmission; ion transport; potassium ion transport
KCNJ10response to blue light; membrane hyperpolarization; regulation of resting membrane potential; potassium ion homeostasis; glutamate uptake involved in synaptic transmission; regulation of sensory perception of pain; response to glucocorticoid stimulus; protein homotetramerization; regulation of long-term neuronal synaptic plasticity; central nervous system myelination; ion transport; potassium ion transport; inflammatory response; synaptic transmission; visual perception; adult walking behavior; potassium ion import; optic nerve development; response to mineralocorticoid stimulus
KCNJ11response to drug; neurological system process; regulation of insulin secretion; negative regulation of insulin secretion; small molecule metabolic process; regulation of membrane potential; response to testosterone stimulus; response to ATP; potassium ion import; synaptic transmission; potassium ion transport; ion transport; energy reserve metabolic process; glucose metabolic process
KCNJ14synaptic transmission; ion transport; potassium ion transport
KCNJ16ion transport; potassium ion transport; synaptic transmission
KCNJ3response to electrical stimulus; synaptic transmission; potassium ion transport; ion transport
KCNJ4ion transport; potassium ion transport; synaptic transmission
KCNJ5ion transport; potassium ion transport; synaptic transmission
KCNJ6synaptic transmission; response to electrical stimulus; thyroid hormone metabolic process; potassium ion transport; ion transport
KCNJ8heart development; defense response to virus; response to exogenous dsRNA; vasodilation; response to lipopolysaccharide; potassium ion import; response to pH; synaptic transmission; potassium ion transport; ion transport; kidney development
KCNK10signal transduction; synaptic transmission; transport; ion transport; potassium ion transport; potassium ion transmembrane transport
KCNK13potassium ion transmembrane transport; ion transport; potassium ion transport; synaptic transmission
KCNK2ion transport; potassium ion transport; G-protein coupled receptor signaling pathway; synaptic transmission; potassium ion transmembrane transport
KCNK3potassium ion transport; cochlea development; potassium ion transmembrane transport; cellular response to hypoxia; cellular response to zinc ion; reduction of cytosolic calcium ion concentration; response to drug; brain development; synaptic transmission; ion transport
KCNK4potassium ion transport; potassium ion transmembrane transport; synaptic transmission; ion transport
KCNK6synaptic transmission; potassium ion transport; ion transport
KCNK7ion transport; potassium ion transmembrane transport; synaptic transmission; potassium ion transport
KCNMA1micturition; transmembrane transport; potassium ion transmembrane transport; smooth muscle contraction involved in micturition; potassium ion transport; response to calcium ion; negative regulation of cell volume; positive regulation of apoptotic process; regulation of membrane potential; response to carbon monoxide; cellular potassium ion homeostasis; blood coagulation; synaptic transmission; ion transport; response to hypoxia; response to osmotic stress
KCNMB1blood coagulation; synaptic transmission; potassium ion transport; ion transport; response to calcium ion; potassium ion transmembrane transport
KCNMB2ion transport; potassium ion transport; synaptic transmission; blood coagulation; regulation of action potential in neuron; regulation of vasoconstriction; detection of calcium ion; regulation of action potential; potassium ion transmembrane transport
KCNMB3synaptic transmission; potassium ion transmembrane transport; potassium ion transport; regulation of action potential in neuron; ion transport; detection of calcium ion; regulation of action potential; blood coagulation
KCNMB4potassium ion transport; ion transport; detection of calcium ion; synaptic transmission; blood coagulation; regulation of action potential in neuron; regulation of vasoconstriction; regulation of neurotransmitter secretion; potassium ion transmembrane transport; regulation of action potential
KCNN2ion transport; potassium ion transport; synaptic transmission; potassium ion transmembrane transport
KCNN3ion transport; potassium ion transport; synaptic transmission; potassium ion transmembrane transport
KCNQ1negative regulation of insulin secretion; regulation of gene expression by genetic imprinting; blood circulation; regulation of heart contraction; gene silencing; response to chemical stimulus; transmembrane transport; regulation of membrane repolarization; potassium ion export; ion transport; synaptic transmission; sensory perception of sound; muscle contraction; potassium ion transport
KCNQ2potassium ion transmembrane transport; transmembrane transport; axon guidance; nervous system development; synaptic transmission; potassium ion transport; ion transport
KCNQ3potassium ion transmembrane transport; transmembrane transport; axon guidance; synaptic transmission; potassium ion transport; ion transport
KCNQ5protein complex assembly; transmembrane transport; synaptic transmission; potassium ion transport; ion transport
KCNRGpotassium ion transport
KCNS1potassium ion transport; transmembrane transport; ion transport; synaptic transmission
KCNS2potassium ion transport; transmembrane transport; ion transport; synaptic transmission
KCNS3regulation of insulin secretion; energy reserve metabolic process; ion transport; potassium ion transport; synaptic transmission; small molecule metabolic process; transmembrane transport
KCNT1potassium ion transport; potassium ion transmembrane transport; ion transport
KCNT2potassium ion transport; potassium ion transmembrane transport; ion transport
KCNV1ion transport; potassium ion transport; synaptic transmission; transmembrane transport
KCTD10potassium ion transport; protein ubiquitination; proteasomal ubiquitin-dependent protein catabolic process
KCTD13cell migration; potassium ion transport; proteasomal ubiquitin-dependent protein catabolic process; stress fiber assembly; DNA replication; protein ubiquitination; negative regulation of Rho protein signal transduction
KCTD16potassium ion transport
KCTD18potassium ion transport
KCTD19potassium ion transport
KCTD21potassium ion transport
KCTD3potassium ion transport
KCTD4potassium ion transport
KCTD8potassium ion transport
KDELC1-
KDELC2-
KDM1Anegative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of DNA binding; negative regulation of apoptotic process; histone H3-K4 demethylation; negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of sequence-specific DNA binding transcription factor activity; muscle cell development; oxidation-reduction process; blood coagulation; chromatin modification; multicellular organismal development; negative regulation of protein binding; histone H3-K9 demethylation; protein demethylation; regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
KDM1Bregulation of DNA methylation; DNA methylation involved in gamete generation; histone H3-K4 demethylation; regulation of transcription, DNA-dependent; multicellular organismal development; regulation of gene expression by genetic imprinting; chromatin modification
KDM2Bchromatin modification; midbrain-hindbrain boundary morphogenesis; fourth ventricle development; histone demethylation; lateral ventricle development; third ventricle development; initiation of neural tube closure; forebrain development; midbrain development; hindbrain development; histone H2A monoubiquitination; negative regulation of neuron apoptosis; embryonic camera-type eye morphogenesis; negative regulation of neural precursor cell proliferation; spermatogenesis; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
KDM3Aformaldehyde biosynthetic process; positive regulation of transcription, DNA-dependent; histone H3-K9 demethylation; androgen receptor signaling pathway; cell differentiation; chromatin modification; hormone-mediated signaling pathway; spermatogenesis
KDM3Bregulation of transcription, DNA-dependent; chromatin modification
KDM4Ahistone H3-K36 demethylation; chromatin modification; histone demethylation; interspecies interaction between organisms; negative regulation of transcription, DNA-dependent
KDM4Bchromatin modification; regulation of transcription, DNA-dependent
KDM4Chistone H3-K9 demethylation; chromatin modification; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter
KDM5Aregulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter; multicellular organismal development; chromatin modification; positive regulation of transcription, DNA-dependent
KDM5Bnegative regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; histone H3-K4 demethylation, trimethyl-H3-K4-specific; histone H3-K4 demethylation; chromatin modification
KDM5Cregulation of transcription, DNA-dependent; chromatin modification; histone H3-K4 demethylation
KDM6Ahistone H3-K4 methylation; chromatin modification
KDM6Binflammatory response; chromatin modification; histone demethylation; negative regulation of transcription from RNA polymerase II promoter
KDM7Achromatin modification; nervous system development; midbrain development; histone H3-K9 demethylation; histone H4-K20 demethylation; positive regulation of transcription, DNA-dependent; histone H3-K36 demethylation; histone H3-K27 demethylation
KDRpositive regulation of cell proliferation; lung alveolus development; vascular endothelial growth factor signaling pathway; surfactant homeostasis; positive regulation of MAPK cascade; interspecies interaction between organisms; cell fate commitment; endothelial cell differentiation; positive regulation of angiogenesis; protein autophosphorylation; vascular endothelial growth factor receptor signaling pathway; negative regulation of apoptotic process; cell maturation; negative regulation of endothelial cell apoptosis; positive regulation of ERK1 and ERK2 cascade; calcium ion homeostasis; positive regulation of focal adhesion assembly; positive regulation of nitric-oxide synthase biosynthetic process; branching morphogenesis of a tube; positive regulation of positive chemotaxis; multicellular organismal development; angiogenesis; ovarian follicle development; vasculogenesis; positive regulation of endothelial cell proliferation; lymph vessel development; positive regulation of mesenchymal cell proliferation; e
KEAP1regulation of transcription, DNA-dependent; in utero embryonic development; negative regulation of gene expression; cytoplasmic sequestering of transcription factor; regulation of epidermal cell differentiation
KELvasoconstriction; proteolysis
KERAvisual perception; response to stimulus
KHDRBS1mRNA processing; cell proliferation; negative regulation of transcription, DNA-dependent; regulation of RNA export from nucleus; cell surface receptor signaling pathway; signal transduction; cell cycle arrest; G2/M transition of mitotic cell cycle; cell cycle
KHKresponse to sucrose stimulus; carbohydrate metabolic process; fructose catabolic process; response to glucose stimulus; response to fructose stimulus; response to zinc ion; response to insulin stimulus; small molecule metabolic process
KHNYN-
KIAA0100-
KIAA0141regulation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process
KIAA0196cell death
KIAA0319neuron migration; multicellular organismal development; nervous system development; negative regulation of dendrite development
KIAA0319L-
KIAA0355-
KIAA0391tRNA processing
KIAA0430negative regulation of phosphatase activity
KIAA0513-
KIAA0556-
KIAA0753-
KIAA0825-
KIAA0895-
KIAA0907-
KIAA0922-
KIAA0930-
KIAA1024-
KIAA1033endosome transport
KIAA1109regulation of epithelial cell differentiation; regulation of cell growth
KIAA1211-
KIAA1211L-
KIAA1217embryonic skeletal system development; multicellular organismal development
KIAA1324positive regulation of autophagic vacuole assembly; positive regulation of vacuole organization; regulation of apoptotic process; macroautophagy
KIAA1324L-
KIAA1429mRNA processing; RNA splicing
KIAA1462cell adhesion
KIAA1468-
KIAA1522-
KIAA1524-
KIAA1551-
KIAA1614-
KIAA1683-
KIAA1715multicellular organismal development; blood coagulation; embryonic forelimb morphogenesis; embryonic digit morphogenesis; limb development
KIAA1755-
KIAA1804-
KIAA1841-
KIAA1919sodium ion transport; ion transport; carbohydrate transport; transmembrane transport
KIAA1958-
KIAA2022DNA replication, removal of RNA primer; regulation of mitotic cell cycle; nucleotide-excision repair, DNA gap filling; DNA replication proofreading; base-excision repair, gap-filling; S phase of mitotic cell cycle
KIDINS220nerve growth factor receptor signaling pathway; activation of MAPKK activity
KIF11microtubule-based movement; spindle assembly involved in mitosis; cell division; blood coagulation; mitotic centrosome separation; mitosis; mitotic spindle organization; spindle organization; cell cycle
KIF14microtubule-based movement
KIF15microtubule-based movement; mitosis; blood coagulation; cell proliferation
KIF16Bendoderm development; Golgi to endosome transport; receptor catabolic process; fibroblast growth factor receptor signaling pathway; early endosome to late endosome transport; epidermal growth factor receptor signaling pathway; cell communication; microtubule-based movement; transport; regulation of receptor recycling; formation of primary germ layer
KIF17metabolic process; vesicle-mediated transport; microtubule-based movement; protein transport; protein complex localization
KIF1BATP catabolic process; cytoskeleton-dependent intracellular transport; anterograde axon cargo transport; neuromuscular synaptic transmission; neuron-neuron synaptic transmission; microtubule-based movement; apoptotic process
KIF1Cmicrotubule-based movement; retrograde vesicle-mediated transport, Golgi to ER
KIF20AM phase of mitotic cell cycle; microtubule bundle formation; microtubule-based movement; protein transport; cytokinesis; mitotic cell cycle; vesicle-mediated transport
KIF20Bcell division; regulation of mitosis; cell cycle arrest; cell cycle; microtubule-based movement; ATP catabolic process; M phase of mitotic cell cycle
KIF21Amicrotubule-based movement
KIF21Bmicrotubule-based movement
KIF22DNA repair; microtubule-based movement; mitosis; blood coagulation
KIF23mitotic spindle elongation; M phase of mitotic cell cycle; mitotic cell cycle; cytokinesis; microtubule-based movement; positive regulation of cell cycle cytokinesis; spindle midzone assembly involved in mitosis; cell cycle cytokinesis; blood coagulation; mitosis
KIF25organelle organization; microtubule-based movement; mitotic sister chromatid segregation
KIF2Bregulation of chromosome segregation; cell division; blood coagulation; microtubule depolymerization; microtubule-based movement; mitotic cell cycle; mitotic prometaphase; M phase of mitotic cell cycle
KIF3Aorganelle organization; microtubule-based movement; blood coagulation; cell projection organization; cilium assembly; plus-end-directed vesicle transport along microtubule
KIF3Bdetermination of left/right symmetry; spindle assembly involved in mitosis; plus-end-directed vesicle transport along microtubule; anterograde axon cargo transport; blood coagulation; mitotic centrosome separation; mitotic spindle organization; microtubule-based movement
KIF3Cmicrotubule-based movement; blood coagulation
KIF4Aanterograde axon cargo transport; blood coagulation; axon guidance; microtubule-based movement; organelle organization
KIF5Acell death; microtubule-based movement; blood coagulation; synaptic transmission
KIF5Bmicrotubule-based movement; vesicle transport along microtubule; stress granule disassembly; cytoplasm organization
KIF6microtubule-based movement
KIF7positive regulation of smoothened signaling pathway; microtubule-based movement; negative regulation of smoothened signaling pathway
KIFAP3blood coagulation; protein localization; negative regulation of cell proliferation; microtubule-based movement; microtubule-based process; protein complex assembly; signal transduction; plus-end-directed vesicle transport along microtubule; positive regulation of calcium-dependent cell-cell adhesion
KIFC2microtubule-based movement
KIRRELexcretion
KISS1Rpositive regulation of synaptic transmission; positive regulation of stress fiber assembly; arachidonic acid secretion; positive regulation of hormone secretion; negative regulation of cell migration; calcium-mediated signaling; negative regulation of cell proliferation; behavior; neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; activation of MAPKK activity
KITmale gonad development; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phospholipase C activity; positive regulation of gene expression; response to radiation; hemopoiesis; peptidyl-tyrosine phosphorylation; cytokine-mediated signaling pathway; stem cell maintenance; signal transduction by phosphorylation; spermatid development; positive regulation of cell proliferation; spermatogenesis; intracellular protein kinase cascade; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; activation of MAPK activity; myeloid progenitor cell differentiation; lymphoid progenitor cell differentiation; glycosphingolipid metabolic process; mast cell proliferation; germ cell programmed cell death; positive regulation of phosphatidylinositol 3-kinase activity; positive regulation of JAK-STAT cascade; protein autophosphorylation; regulation of developmental pigmentation; positive regulation of sequence-specific DNA binding transcription factor activity; mast
KITLGnegative regulation of apoptotic process; ovarian follicle development; neural crest cell migration; positive regulation of myeloid leukocyte differentiation; cell adhesion; signal transduction; cell proliferation; positive regulation of cell proliferation; male gonad development; hemopoiesis; negative regulation of mast cell apoptosis; embryonic hemopoiesis; germ cell programmed cell death; positive regulation of mast cell proliferation; positive regulation of MAP kinase activity; positive regulation of melanocyte differentiation; positive regulation of DNA replication; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of Ras protein signal transduction
KLcarbohydrate metabolic process; positive regulation of bone mineralization; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; insulin receptor signaling pathway; aging; energy reserve metabolic process; acute inflammatory response
KLBinsulin receptor signaling pathway; positive regulation of cell proliferation; fibroblast growth factor receptor signaling pathway; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; carbohydrate metabolic process
KLC1microtubule-based movement; blood coagulation; stress granule disassembly
KLC3metabolic process
KLC4-
KLF12negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter
KLF3multicellular organismal development; regulation of transcription, DNA-dependent
KLF5microvillus assembly; positive regulation of transcription, DNA-dependent; angiogenesis; positive regulation of cell proliferation; transcription from RNA polymerase II promoter
KLF8regulation of transcription, DNA-dependent
KLF9cellular response to thyroid hormone stimulus; regulation of transcription from RNA polymerase II promoter; embryo implantation; progesterone receptor signaling pathway
KLHDC1-
KLHDC2-
KLHDC7A-
KLHDC7B-
KLHDC9-
KLHL1adult walking behavior; locomotory behavior; actin cytoskeleton organization; cerebellar Purkinje cell layer development; dendrite development
KLHL10cell morphogenesis; spermatid development; male gonad development; homeostasis of number of cells within a tissue; male genitalia morphogenesis; fertilization
KLHL11-
KLHL12Wnt receptor signaling pathway
KLHL13mitosis; cell cycle; cytokinesis; protein ubiquitination
KLHL14-
KLHL15-
KLHL17actin cytoskeleton organization; brain development
KLHL18-
KLHL2intracellular protein transport
KLHL20protein ubiquitination; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of apoptotic process; response to interferon-alpha; cytoskeleton organization
KLHL24-
KLHL25-
KLHL31regulation of transcription, DNA-dependent
KLHL34-
KLHL36-
KLHL38-
KLHL4-
KLHL41-
KLHL42-
KLHL5-
KLHL8-
KLHL9cell cycle; protein ubiquitination; cytokinesis; mitosis
KLK12proteolysis
KLK13protein processing; proteolysis
KLK14seminal clot liquefaction; epidermis morphogenesis; proteolysis; positive regulation of G-protein coupled receptor protein signaling pathway; negative regulation of G-protein coupled receptor protein signaling pathway; fertilization
KLK3proteolysis; negative regulation of angiogenesis
KLK5proteolysis; positive regulation of G-protein coupled receptor protein signaling pathway; epidermis development
KLK6tissue regeneration; hormone metabolic process; myelination; amyloid precursor protein metabolic process; collagen catabolic process; protein autoprocessing; response to wounding; positive regulation of G-protein coupled receptor protein signaling pathway; central nervous system development; proteolysis; regulation of cell differentiation
KLK7epidermis development; proteolysis
KLK8regulation of synapse organization; neuron projection morphogenesis; negative regulation of axon regeneration; keratinocyte proliferation; negative regulation of myelination; response to wounding; cell death; memory; proteolysis
KLK9proteolysis
KLKB1Factor XII activation; proteolysis; inflammatory response; blood coagulation; blood coagulation, intrinsic pathway; zymogen activation; plasminogen activation; positive regulation of fibrinolysis
KLRD1cell surface receptor signaling pathway; regulation of immune response
KLRG1cell surface receptor signaling pathway; cellular defense response; innate immune response; regulation of immune response; inflammatory response
KMT2A-
KMT2C-
KMT2E-
KMT5Anegative regulation of transcription, DNA-dependent; cell cycle; mitosis; negative regulation of transcription from RNA polymerase II promoter; regulation of DNA damage response, signal transduction by p53 class mediator; histone lysine methylation; cell division; peptidyl-lysine monomethylation; chromatin modification
KMT5Bregulation of transcription, DNA-dependent; histone lysine methylation; peptidyl-lysine methylation; chromatin modification
KMT5Cpeptidyl-lysine methylation; chromatin modification; regulation of transcription, DNA-dependent; histone methylation
KNDC1cerebellar granule cell differentiation; regulation of dendrite morphogenesis; regulation of small GTPase mediated signal transduction; protein phosphorylation; regulation of catalytic activity
KNG1negative regulation of blood coagulation; platelet degranulation; smooth muscle contraction; inflammatory response; negative regulation of cell adhesion; elevation of cytosolic calcium ion concentration; blood coagulation; blood coagulation, intrinsic pathway; platelet activation; positive regulation of urine volume; positive regulation of renal sodium excretion; vasodilation; positive regulation of apoptotic process
KPNA6NLS-bearing substrate import into nucleus
KPRP-
KPTNsensory perception of sound; cellular component movement; actin filament organization
KRASpositive regulation of nitric-oxide synthase activity; nerve growth factor receptor signaling pathway; regulation of long-term neuronal synaptic plasticity; leukocyte migration; positive regulation of NF-kappaB transcription factor activity; striated muscle cell differentiation; response to glucocorticoid stimulus; response to mineralocorticoid stimulus; positive regulation of MAP kinase activity; negative regulation of neuron apoptosis; MAPK cascade; activation of MAPKK activity; positive regulation of protein phosphorylation; signal transduction; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction; axon guidance; blood coagulation; positive regulation of cell proliferation; insulin receptor signaling pathway; visual learning; fibroblast growth factor receptor signaling pathway; Ras protein signal transduction; positive regulation of gene expression; cytokine-mediated signaling pathway; actin cytoskeleton organization; regulation of synaptic transmission, GABAergic;
KRI1-
KRIT1regulation of establishment of cell polarity; positive regulation of protein binding; negative regulation of angiogenesis; negative regulation of endothelial cell migration; small GTPase mediated signal transduction; negative regulation of endothelial cell proliferation; cell redox homeostasis; negative regulation of endothelial cell apoptosis
KRR1rRNA processing
KRT1epidermis development; fibrinolysis; regulation of angiogenesis; complement activation, lectin pathway; response to oxidative stress
KRT10epidermis development; keratinocyte differentiation; cellular response to calcium ion
KRT13epidermis development; response to radiation; tongue morphogenesis; cellular response to retinoic acid
KRT15epidermis development
KRT18anatomical structure morphogenesis; tumor necrosis factor-mediated signaling pathway; Golgi to plasma membrane CFTR protein transport; negative regulation of apoptotic process; interspecies interaction between organisms; cell cycle
KRT19cell differentiation involved in embryonic placenta development; interspecies interaction between organisms; sarcomere organization; response to estrogen stimulus
KRT2epidermis development; keratinization; keratinocyte activation; keratinocyte proliferation; keratinocyte migration
KRT23-
KRT24-
KRT25intermediate filament organization; hair follicle morphogenesis
KRT26-
KRT27hair follicle morphogenesis
KRT28-
KRT32epidermis development
KRT34epidermis development
KRT36regulation of keratinocyte differentiation
KRT4negative regulation of epithelial cell proliferation; epithelial cell differentiation; cytoskeleton organization
KRT40-
KRT5cell junction assembly; hemidesmosome assembly; epidermis development
KRT71hair follicle morphogenesis
KRT72-
KRT73-
KRT74-
KRT75-
KRT78-
KRT79-
KRT80-
KRT83epidermis development
KRT84regulation of keratinocyte differentiation; hair follicle development; nail development
KRT85epidermis development
KRT9spermatogenesis; epidermis development; skin development; intermediate filament organization
KRTAP1-5-
KRTAP11-1-
KRTAP12-3-
KRTAP13-3-
KRTAP13-4-
KRTAP24-1-
KRTAP27-1-
KRTAP3-1-
KRTAP4-3-
KRTCAP2-
KRTDAPcell differentiation
KTN1microtubule-based movement
L1CAMcell adhesion; leukocyte cell-cell adhesion; homophilic cell adhesion; heterophilic cell-cell adhesion; cell surface receptor signaling pathway; multicellular organismal development; nervous system development; axon guidance; blood coagulation; cell death; positive regulation of cell-cell adhesion; cell differentiation; neuron projection development; cell-cell adhesion mediated by integrin; homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; leukocyte migration; chemotaxis
L3HYPDH-
L3MBTL2chromatin modification; regulation of transcription, DNA-dependent
L3MBTL3regulation of transcription, DNA-dependent; chromatin modification
L3MBTL4chromatin modification
LACC1-
LACE1-
LACRTtear secretion; positive regulation of NFAT protein import into nucleus; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of secretion; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of epithelial cell proliferation; protein localization in Golgi apparatus; calcineurin-NFAT signaling cascade; calcium-mediated signaling; positive regulation of cell proliferation
LAD1-
LAIR1-
LALBAcell-cell signaling; induction of apoptosis; lactose biosynthetic process; signal transduction; defense response to bacterium
LAMA1retina development in camera-type eye; neuron projection development; establishment of epithelial cell apical/basal polarity; regulation of embryonic development; epithelial tube branching involved in lung morphogenesis; morphogenesis of an epithelial sheet; regulation of cell migration; regulation of cell adhesion; tissue development; cell surface receptor signaling pathway; axon guidance; branching involved in salivary gland morphogenesis; retinal blood vessel morphogenesis
LAMA2regulation of embryonic development; muscle organ development; regulation of cell adhesion; regulation of cell migration; positive regulation of synaptic transmission, cholinergic
LAMA3epidermis development; regulation of cell adhesion; regulation of cell migration; hemidesmosome assembly; cell junction assembly; regulation of embryonic development
LAMA4blood vessel development; regulation of cell adhesion; regulation of cell migration; regulation of embryonic development; brown fat cell differentiation
LAMA5regulation of embryonic development; odontogenesis of dentin-containing tooth; cell recognition; cell proliferation; embryo development; organ morphogenesis; morphogenesis of embryonic epithelium; cell migration; cell differentiation; regulation of cell adhesion; lung development; regulation of cell migration; substrate adhesion-dependent cell spreading; regulation of cell proliferation; cilium assembly; endothelial cell differentiation; focal adhesion assembly; branching involved in salivary gland morphogenesis; establishment of protein localization in plasma membrane; muscle organ development; integrin-mediated signaling pathway; cytoskeleton organization; hair follicle development; neural crest cell migration; morphogenesis of a polarized epithelium; branching involved in ureteric bud morphogenesis; angiogenesis
LAMB1embryo implantation; cell adhesion; negative regulation of cell adhesion; positive regulation of epithelial cell proliferation; odontogenesis; substrate adhesion-dependent cell spreading; neuron projection development; positive regulation of cell migration; axon guidance
LAMB2astrocyte development; retina development in camera-type eye; metanephric glomerular basement membrane development; metanephric glomerular visceral epithelial cell development; axon extension involved in regeneration; neuron projection development; Schwann cell development; visual perception; neuromuscular junction development; cell morphogenesis involved in differentiation; cell adhesion
LAMB3cell adhesion; epidermis development; hemidesmosome assembly; cell junction assembly; brown fat cell differentiation
LAMB4cell adhesion
LAMC1extracellular matrix disassembly; protein complex assembly; cell adhesion; axon guidance; endoderm development; cell migration; neuron projection development; hemidesmosome assembly; substrate adhesion-dependent cell spreading; positive regulation of epithelial cell proliferation
LAMC2hemidesmosome assembly; epidermis development; cell adhesion; cell junction assembly
LAMC3retina development in camera-type eye; astrocyte development; visual perception; cell adhesion; cell morphogenesis involved in differentiation
LAMP2platelet activation; blood coagulation; platelet degranulation
LAMP3cell proliferation
LANCL1G-protein coupled receptor signaling pathway
LANCL2negative regulation of transcription, DNA-dependent; positive regulation of abscisic acid mediated signaling pathway
LANCL3-
LAP3proteolysis; metabolic process
LAPTM4Atransport
LARP1-
LARP4cytoskeleton organization; regulation of cell morphogenesis
LARP4B-
LARP6regulation of translation; RNA processing
LARSleucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; gene expression
LARS2tRNA aminoacylation for protein translation; leucyl-tRNA aminoacylation; gene expression
LAS1LrRNA processing
LAT2calcium-mediated signaling; intracellular signal transduction; B cell activation; mast cell degranulation; B cell receptor signaling pathway
LATS1protein phosphorylation; sister chromatid segregation; cell cycle; G2/M transition of mitotic cell cycle; regulation of protein complex assembly; positive regulation of peptidyl-serine phosphorylation; hormone-mediated signaling pathway; regulation of actin filament polymerization; negative regulation of canonical Wnt receptor signaling pathway; cell division; cytoplasmic sequestering of protein; mitosis; hippo signaling cascade; negative regulation of cyclin-dependent protein kinase activity
LATS2regulation of organ growth; hormone-mediated signaling pathway; intracellular protein kinase cascade; mitosis; cell cycle; protein phosphorylation; G1/S transition of mitotic cell cycle; hippo signaling cascade; negative regulation of cyclin-dependent protein kinase activity; keratinocyte differentiation; cellular protein localization; negative regulation of canonical Wnt receptor signaling pathway; cell division
LAYN-
LBHD1-
LBPpositive regulation of tumor necrosis factor production; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of macrophage activation; negative regulation of growth of symbiont in host; innate immune response; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; positive regulation of respiratory burst involved in inflammatory response; cellular response to lipopolysaccharide; cellular response to lipoteichoic acid; lipid transport; positive regulation of neutrophil chemotaxis; positive regulation of interleukin-6 production; leukocyte chemotaxis involved in inflammatory response; macrophage activation involved in immune response; transport; acute-phase response; cellular defense response; Toll signaling pathway; opsonization; lipopolysaccharide-mediated signaling pathway; positive regulation of interleukin-8 production; positive regulation of chemokine production; negative re
LBRcholesterol biosynthetic process; small molecule metabolic process; oxidation-reduction process
LCA5protein transport
LCKpositive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of T cell receptor signaling pathway; response to hydrogen peroxide; interspecies interaction between organisms; positive regulation of gamma-delta T cell differentiation; protein autophosphorylation; regulation of defense response to virus by virus; T cell receptor signaling pathway; B cell receptor signaling pathway; positive regulation of T cell activation; leukocyte migration; release of sequestered calcium ion into cytosol; regulation of lymphocyte activation; positive regulation of uterine smooth muscle contraction; blood coagulation; response to drug; induction of apoptosis; cellular zinc ion homeostasis; activation of cysteine-type endopeptidase activity involved in apoptotic process; cell surface receptor signaling pathway; aging; response to mechanical stimulus; protein phosphorylation; response to zinc ion; viral reproduction; peptidyl-tyrosine phosphorylation; hemopoiesis; platelet activation; T cell differentiat
LCLAT1phospholipid biosynthetic process; metabolic process; multicellular organismal development
LCNL1-
LCORnegative regulation of transcription from RNA polymerase II promoter
LCP1T cell activation involved in immune response; organ regeneration; regulation of intracellular protein transport; actin filament bundle assembly
LCTresponse to drug; response to ethanol; small molecule metabolic process; polysaccharide digestion; response to estrogen stimulus; response to starvation; response to lead ion; response to nickel cation; response to sucrose stimulus; response to hormone stimulus; response to nutrient; carbohydrate metabolic process; response to hypoxia
LCTLcarbohydrate metabolic process
LDB1head development; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; gastrulation with mouth forming second; hair follicle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; Wnt receptor signaling pathway; positive regulation of hemoglobin biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cell adhesion; negative regulation of erythrocyte differentiation; anterior/posterior axis specification; cerebellum development; cerebellar Purkinje cell differentiation; cellular component assembly; neuron differentiation; epithelial structure maintenance; regulation of transcription elongation, DNA-dependent; somatic stem cell maintenance; histone H3-K4 acetylation
LDB2positive regulation of transcription from RNA polymerase II promoter; hair follicle development; epithelial structure maintenance; somatic stem cell maintenance; positive regulation of cellular component biogenesis
LDB3-
LDHApyruvate metabolic process; glycolysis; cellular carbohydrate metabolic process; small molecule metabolic process
LDHAL6Aglycolysis; cellular carbohydrate metabolic process
LDHCglycolysis; cellular carbohydrate metabolic process
LDLRinterspecies interaction between organisms; cholesterol import; small molecule metabolic process; cholesterol homeostasis; lipoprotein metabolic process; low-density lipoprotein particle clearance; cholesterol transport; phospholipid transport; lipid metabolic process; transport; endocytosis; receptor-mediated endocytosis; intestinal cholesterol absorption; cholesterol metabolic process; positive regulation of triglyceride biosynthetic process; regulation of phosphatidylcholine catabolic process; steroid metabolic process
LDLRAD2-
LDLRAD3-
LDLRAD4-
LDLRAP1receptor internalization; receptor-mediated endocytosis; positive regulation of cholesterol metabolic process; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; regulation of establishment of protein localization in plasma membrane; positive regulation of receptor-mediated endocytosis; regulation of protein binding; amyloid precursor protein metabolic process; cholesterol homeostasis; positive regulation of signal transduction; cholesterol metabolic process; steroid metabolic process; transport
LEAP2defense response to bacterium
LECT1cell differentiation; negative regulation of vascular endothelial growth factor receptor signaling pathway; cartilage development; multicellular organismal development; proteoglycan metabolic process; negative regulation of angiogenesis; skeletal system development; endothelial cell morphogenesis; negative regulation of endothelial cell proliferation
LEF1positive regulation by host of viral transcription; positive regulation of gene expression; response to lithium ion; negative regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; osteoblast differentiation; positive regulation of cell proliferation; brain development; histone H3 acetylation; skin development; tongue development; negative regulation of DNA binding; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; odontogenesis of dentin-containing tooth; B cell proliferation; T cell receptor V(D)J recombination; negative regulation of interleukin-5 production; histone H4 acetylation; T-helper 1 cell differentiation; negative regulation of striated muscle tissue development; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; alpha-beta T cell differentiation; eye pigmen
LEMD2skeletal muscle cell differentiation
LEMD3negative regulation of activin receptor signaling pathway; negative regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway
LENG8-
LENG9RNA metabolic process
LEO1histone H2B ubiquitination; histone monoubiquitination; regulation of transcription, DNA-dependent
LEPRnegative regulation of hydrolase activity; cholesterol metabolic process; multicellular organismal development; cell surface receptor signaling pathway; energy reserve metabolic process
LETM1cristae formation
LETM2-
LFNGovarian follicle development; female meiosis; compartment pattern specification; pattern specification process; organ morphogenesis
LGALS1cellular response to organic cyclic compound; negative regulation of neuron projection development; cellular response to glucose stimulus; response to axon injury; myoblast differentiation; positive regulation of I-kappaB kinase/NF-kappaB cascade; response to drug; positive regulation of erythrocyte aggregation; multicellular organismal response to stress; negative regulation of cell-substrate adhesion; signal transduction; apoptotic process; regulation of apoptotic process
LGALS3BPcellular defense response; signal transduction; cell adhesion
LGALS8-
LGI2-
LGI3regulation of exocytosis
LGR4epithelial cell proliferation; tube morphogenesis; canonical Wnt receptor signaling pathway involved in metanephric kidney development; cell differentiation involved in metanephros development; positive regulation of branching involved in ureteric bud morphogenesis; metanephric nephron tubule morphogenesis; metanephric glomerulus development; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; male genitalia development; G-protein coupled receptor signaling pathway
LGR5G-protein coupled receptor signaling pathway
LGSNnitrogen compound metabolic process; glutamine biosynthetic process
LHCGRseminiferous tubule development; regulation of steroid hormone biosynthetic process; uterus development; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of calcium-mediated signaling; arachidonic acid secretion; positive regulation of hormone biosynthetic process; development of secondary male sexual characteristics; response to drug; hormone-mediated signaling pathway; protein targeting to lysosome; G-protein coupled receptor signaling pathway; male genitalia development; G-protein signaling, coupled to cyclic nucleotide second messenger; ovarian follicle development; G-protein signaling, coupled to cAMP nucleotide second messenger; activation of adenylate cyclase activity; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; spermatogenesis; central nervous system development; male gonad development
LHFP-
LHFPL1-
LHFPL4-
LHFPL5auditory receptor cell stereocilium organization; sensory perception of sound
LHPPprotein dephosphorylation; phosphate-containing compound metabolic process; metabolic process
LHX1head development; uterine epithelium development; vagina development; cervix development; oviduct development; uterus development; embryonic retina morphogenesis in camera-type eye; retina development in camera-type eye; pronephros development; embryonic viscerocranium morphogenesis; anatomical structure formation involved in morphogenesis; positive regulation of transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; positive regulation of embryonic development; horizontal cell localization; nephric duct elongation; cellular response to fibroblast growth factor stimulus; epithelium development; paramesonephric duct development; comma-shaped body morphogenesis; S-shaped body morphogenesis; renal vesicle morphogenesis; mesonephric duct development; nephric duct morphogenesis; metanephric glomerulus development; metanephric comma-shaped body morphogenesis; metanephric renal vesicle morphogenesis; metanephric S-shaped body morphogenesis; primitive streak formation; positive regulation
LHX2neural tube closure; negative regulation of transcription regulatory region DNA binding; anatomical structure formation involved in morphogenesis; positive regulation of transcription from RNA polymerase II promoter; neuron differentiation; axon guidance; brain development; mesoderm development; dorsal/ventral pattern formation; telencephalon regionalization; neurogenesis; positive regulation of transcription, DNA-dependent
LHX3inner ear development; organ morphogenesis; positive regulation of transcription, DNA-dependent
LHX5spinal cord association neuron differentiation; cerebellum development; cerebellar Purkinje cell differentiation; hippocampus development; positive regulation of transcription, DNA-dependent; regulation of cell proliferation; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; forebrain neuron differentiation; cell proliferation in forebrain
LHX6forebrain neuron development; multicellular organismal development; cerebral cortex neuron differentiation; cell differentiation; cell maturation; forebrain neuron fate commitment; cerebral cortex GABAergic interneuron migration; cerebral cortex tangential migration; cerebral cortex radially oriented cell migration; nervous system development; regulation of transcription, DNA-dependent
LHX8odontogenesis of dentin-containing tooth; learning or memory; female gonad development; forebrain neuron development
LHX9motor axon guidance; cell proliferation; male gonad development; female gonad development; negative regulation of transcription, DNA-dependent; gonad morphogenesis
LIASresponse to lipopolysaccharide; inflammatory response; neural tube closure; response to oxidative stress; lipoate biosynthetic process
LIFretina development in camera-type eye; positive regulation of corticotropin secretion; positive regulation of peptidyl-tyrosine phosphorylation; leukemia inhibitory factor signaling pathway; positive regulation of astrocyte differentiation; neuron development; muscle organ morphogenesis; negative regulation of hormone secretion; lung alveolus development; maternal process involved in female pregnancy; transdifferentiation; lung vasculature development; lung lobe morphogenesis; trophoblast giant cell differentiation; spongiotrophoblast differentiation; negative regulation of ERK1 and ERK2 cascade; regulation of metanephric nephron tubule epithelial cell differentiation; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; positive regulation of transcription from RNA polymerase II promoter; decidualization; immune response; blood vessel remodeling; multicellular organismal development; embryo implantation; positive regulation of cell proliferation; negative regulat
LIFRcytokine-mediated signaling pathway; ciliary neurotrophic factor-mediated signaling pathway; leukemia inhibitory factor signaling pathway; neuron projection morphogenesis; positive regulation of anti-apoptosis; response to chemical stimulus; response to cytokine stimulus; organ regeneration; positive regulation of cell proliferation; cell surface receptor signaling pathway
LIG1transcription-coupled nucleotide-excision repair; cell division; DNA ligation involved in DNA repair; V(D)J recombination; telomere maintenance via semi-conservative replication; anatomical structure morphogenesis; DNA recombination; double-strand break repair; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair; base-excision repair; DNA repair; DNA strand elongation involved in DNA replication; DNA ligation; DNA replication; DNA metabolic process; double-strand break repair via homologous recombination; telomere maintenance; S phase of mitotic cell cycle; mitotic cell cycle; telomere maintenance via recombination
LIG3cell cycle; cell division; DNA ligation involved in DNA repair; V(D)J recombination; spermatogenesis; reciprocal meiotic recombination; DNA recombination; base-excision repair; DNA repair; DNA ligation; DNA replication
LIG4T cell differentiation in thymus; V(D)J recombination; T cell receptor V(D)J recombination; somatic stem cell maintenance; negative regulation of neuron apoptosis; isotype switching; positive regulation of fibroblast proliferation; positive regulation of neurogenesis; DNA ligation involved in DNA recombination; DNA ligation involved in DNA repair; chromosome organization; cell division; neuron apoptosis; cellular response to lithium ion; DNA repair; provirus integration; initiation of viral infection; single strand break repair; in utero embryonic development; pro-B cell differentiation; DNA replication; DNA ligation; nucleotide-excision repair, DNA gap filling; double-strand break repair; double-strand break repair via nonhomologous end joining; cell cycle; central nervous system development; cell proliferation; response to X-ray; response to gamma radiation; viral reproduction
LILRA5innate immune response
LILRB4negative regulation of osteoclast differentiation; signal transduction
LIM2lens development in camera-type eye; cell-cell junction assembly
LIMCH1actomyosin structure organization
LIMD1cytoplasmic mRNA processing body assembly; regulation of transcription, DNA-dependent; cytoskeleton organization; signal transduction; multicellular organismal development; regulation of cell shape; gene silencing by miRNA; negative regulation of transcription, DNA-dependent; cell migration
LIMK2regulation of phosphorylation; phosphorylation; spermatogenesis
LIN54mitotic cell cycle; regulation of transcription, DNA-dependent
LIN9DNA replication; mitotic cell cycle
LINC01565-
LINGO2-
LINGO4-
LINS1-
LIPElipid metabolic process; diacylglycerol catabolic process; small molecule metabolic process; response to drug; triglyceride catabolic process; lipid catabolic process; cholesterol metabolic process; steroid metabolic process; female pregnancy; protein phosphorylation
LIPFtriglyceride metabolic process; lipid catabolic process
LIPGpositive regulation of high-density lipoprotein particle clearance; lipid metabolic process; response to nutrient; lipid catabolic process; cell proliferation; phospholipid catabolic process; regulation of lipoprotein metabolic process; reverse cholesterol transport; cholesterol homeostasis; high-density lipoprotein particle remodeling; phospholipid homeostasis; positive regulation of cholesterol transport
LIPHlipid catabolic process
LIPIlipid catabolic process
LIPJlipid catabolic process
LKAAEAR1-
LLGL1maintenance of apical/basal cell polarity; exocytosis; cortical actin cytoskeleton organization; protein complex assembly
LLGL2cell division; regulation of establishment or maintenance of cell polarity; cell cycle; exocytosis
LLPH-
LMAN1blood coagulation; positive regulation of organelle organization; protein transport; vesicle-mediated transport; protein N-linked glycosylation via asparagine; protein exit from endoplasmic reticulum; early endosome to Golgi transport; post-translational protein modification; cellular protein metabolic process; Golgi organization; ER to Golgi vesicle-mediated transport; protein folding
LMAN2protein transport
LMAN2Lprotein transport; ER to Golgi vesicle-mediated transport; protein folding
LMBR1embryonic digit morphogenesis
LMBR1Lendocytosis
LMBRD2-
LMCD1regulation of cardiac muscle hypertrophy; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of calcineurin-NFAT signaling cascade
LMF2-
LMNAprotein localization to nucleus; cellular response to hypoxia; sterol regulatory element binding protein import into nucleus; apoptotic process; cellular component disassembly involved in apoptosis; activation of signaling protein activity involved in unfolded protein response; nuclear envelope organization; spermatogenesis; muscle organ development; regulation of cell migration; establishment or maintenance of microtubule cytoskeleton polarity; endoplasmic reticulum unfolded protein response; ventricular cardiac muscle cell development; positive regulation of cell aging; regulation of apoptotic process
LMNB1apoptotic process; cellular component disassembly involved in apoptosis
LMNB2-
LMNTD1cell proliferation
LMO7protein ubiquitination
LMTK2transferrin transport; receptor recycling; protein phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; endocytic recycling; protein autophosphorylation; early endosome to late endosome transport
LNP1-
LNPEPantigen processing and presentation of exogenous peptide antigen via MHC class I; protein polyubiquitination; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; proteolysis; cell-cell signaling; female pregnancy; protein catabolic process
LNX1protein homooligomerization; protein ubiquitination involved in ubiquitin-dependent protein catabolic process
LNX2protein homooligomerization
LOC81691-
LONP1protein homooligomerization; response to hypoxia; misfolded or incompletely synthesized protein catabolic process; mitochondrion organization; mitochondrial DNA metabolic process; cellular response to oxidative stress; proteolysis involved in cellular protein catabolic process; oxidation-dependent protein catabolic process; mitochondrial genome maintenance
LONP2misfolded or incompletely synthesized protein catabolic process; peroxisome organization; protein targeting to peroxisome; regulation of fatty acid beta-oxidation; response to organic cyclic compound; signal peptide processing; proteolysis
LONRF1proteolysis
LONRF2proteolysis
LOXL3oxidation-reduction process
LOXL4-
LPAlipid transport; transport; lipid metabolic process; proteolysis; receptor-mediated endocytosis; blood circulation; negative regulation of endopeptidase activity; lipoprotein metabolic process; small molecule metabolic process
LPAR1bleb assembly; neurogenesis; negative regulation of neuron projection development; positive regulation of cell death; elevation of cytosolic calcium ion concentration; activation of phospholipase C activity; G-protein coupled receptor signaling pathway; activation of MAPK activity; positive regulation of smooth muscle cell chemotaxis; positive regulation of Rho protein signal transduction; myelination; positive regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAPK cascade; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; positive regulation of dendritic spine development; cellular response to oxygen levels
LPAR2positive regulation of Rho protein signal transduction; activation of MAPK activity; G-protein coupled receptor signaling pathway; activation of phospholipase C activity; elevation of cytosolic calcium ion concentration; positive regulation of MAPK cascade
LPAR4G-protein coupled receptor signaling pathway
LPAR6G-protein coupled receptor signaling pathway
LPCAT1phospholipid biosynthetic process; retina development in camera-type eye; metabolic process
LPCAT3phospholipid biosynthetic process
LPCAT4phospholipid biosynthetic process; metabolic process
LPIN1cellular response to insulin stimulus; small molecule metabolic process; regulation of transcription, DNA-dependent; cellular lipid metabolic process; organ regeneration; triglyceride mobilization; fatty acid catabolic process; triglyceride biosynthetic process
LPIN3lipid metabolic process; fatty acid metabolic process; dephosphorylation
LPOresponse to oxidative stress; hydrogen peroxide catabolic process
LRBA-
LRCH1-
LRCH3-
LRCH4negative regulation of transcription, DNA-dependent; nervous system development
LRFN2-
LRFN3cell adhesion
LRFN4-
LRFN5-
LRG1brown fat cell differentiation
LRGUK-
LRIF1regulation of transcription, DNA-dependent
LRIG1-
LRIG2-
LRIT1-
LRIT2-
LRIT3-
LRP1activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; negative regulation of platelet-derived growth factor receptor-beta signaling pathway; positive regulation of protein transport; positive regulation of anti-apoptosis; apoptotic cell clearance; lipoprotein transport; lipoprotein metabolic process; aorta morphogenesis; regulation of actin cytoskeleton organization; regulation of cholesterol transport; positive regulation of lipid transport; negative regulation of Wnt receptor signaling pathway; negative regulation of smooth muscle cell migration; positive regulation of cholesterol efflux; cell proliferation; aging; regulation of phospholipase A2 activity; receptor-mediated endocytosis; multicellular organismal development
LRP10lipid transport; endocytosis; lipid metabolic process
LRP12regulation of growth; endocytosis; signal transduction
LRP1Breceptor-mediated endocytosis; protein transport
LRP2cell proliferation; steroid metabolic process; receptor-mediated endocytosis; endocytosis; vitamin metabolic process; lipid metabolic process; protein glycosylation; vitamin D metabolic process; small molecule metabolic process; forebrain development
LRP3receptor-mediated endocytosis
LRP4odontogenesis of dentin-containing tooth; negative regulation of canonical Wnt receptor signaling pathway; synaptic growth at neuromuscular junction; anatomical structure development; receptor clustering; embryonic digit morphogenesis; negative regulation of ossification; cell differentiation; proximal/distal pattern formation; dorsal/ventral pattern formation; protein localization; multicellular organismal development; endocytosis; hair follicle development; kidney development
LRP5endocytosis; glucose catabolic process; osteoblast development; positive regulation of mesenchymal cell proliferation; gastrulation with mouth forming second; negative regulation of protein serine/threonine kinase activity; regulation of blood pressure; positive regulation of transcription from RNA polymerase II promoter; multicellular organismal development; retinal blood vessel morphogenesis; positive regulation of cell proliferation; anterior/posterior pattern specification; Wnt receptor signaling pathway; embryonic limb morphogenesis; cholesterol homeostasis; Wnt receptor signaling pathway involved in dorsal/ventral axis specification; positive regulation of fat cell differentiation; negative regulation of osteoblast differentiation; positive regulation of mitosis; positive regulation of transcription, DNA-dependent; bone remodeling; bone marrow development; embryonic camera-type eye morphogenesis; retina morphogenesis in camera-type eye; embryonic retina morphogenesis in camera-type eye; canonical Wnt re
LRP6embryonic retina morphogenesis in camera-type eye; palate development; convergent extension; branching involved in mammary gland duct morphogenesis; canonical Wnt receptor signaling pathway; regulation of cell development; face morphogenesis; bone morphogenesis; positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification; response to folic acid; positive regulation of sequence-specific DNA binding transcription factor activity; negative regulation of epithelial cell proliferation; embryonic camera-type eye morphogenesis; bone remodeling; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of cell cycle; positive regulation of bone resorption; Wnt receptor signaling pathway involved in somitogenesis; midbrain-hindbrain boundary development; negative regulation of planar cell polarity pathway involved in neural tube closure; negative regulation of planar cell polarity pathway involv
LRPPRCregulation of transcription, DNA-dependent; transport; mitochondrion transport along microtubule; mRNA transport
LRR1-
LRRC1-
LRRC14-
LRRC15-
LRRC16B-
LRRC17bone marrow development; negative regulation of osteoclast differentiation; osteoblast proliferation; osteoblast differentiation
LRRC18-
LRRC19-
LRRC2-
LRRC23-
LRRC25-
LRRC28-
LRRC3-
LRRC30-
LRRC32-
LRRC34-
LRRC36-
LRRC39-
LRRC3B-
LRRC4-
LRRC41-
LRRC46-
LRRC49-
LRRC4B-
LRRC4Cregulation of axonogenesis
LRRC52-
LRRC6diplotene; male gonad development; pachytene
LRRC61-
LRRC66-
LRRC7-
LRRC73-
LRRC8Acell differentiation; pre-B cell differentiation
LRRC8D-
LRRC8E-
LRRFIP1regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
LRRFIP2Wnt receptor signaling pathway
LRRIQ1-
LRRIQ3-
LRRK1small GTPase mediated signal transduction
LRRK2negative regulation of branching morphogenesis of a nerve; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein phosphorylation; response to oxidative stress; small GTPase mediated signal transduction; negative regulation of neuroblast proliferation; neuromuscular junction development; determination of adult lifespan; positive regulation of autophagy; negative regulation of neuron maturation; peptidyl-serine phosphorylation; olfactory bulb development; tangential migration from the subventricular zone to the olfactory bulb; positive regulation of protein ubiquitination; positive regulation of cell death; regulation of kidney size; exploration behavior; regulation of locomotion; regulation of membrane potential; positive regulation of programmed cell death; positive regulation of GTPase activity; protein autophosphorylation; intracellular distribution of mitochondria; positive regulation of dopamine receptor signaling pathway; negative regulation of d
LRRN1-
LRRN2signal transduction; cell adhesion
LRRN3positive regulation of protein phosphorylation
LRRN4CL-
LRRTM1-
LRRTM3-
LRSAM1protein transport; protein catabolic process; protein polyubiquitination; negative regulation of endocytosis; non-lytic virus budding; protein autoubiquitination; ubiquitin-dependent endocytosis
LRTM2-
LSAMPcell adhesion; nervous system development
LSG1protein transport; nuclear export
LSRliver development; embryo development; regulation of lipid metabolic process
LSSsmall molecule metabolic process; sterol metabolic process; steroid metabolic process; cholesterol biosynthetic process; steroid biosynthetic process
LTA4HType I pneumocyte differentiation; small molecule metabolic process; response to peptide hormone stimulus; peptide catabolic process; leukotriene biosynthetic process; response to zinc ion; inflammatory response; prostanoid metabolic process; proteolysis
LTB4Rcellular component movement; muscle contraction; inflammatory response; immune response; G-protein coupled receptor signaling pathway; activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
LTB4R2chemotaxis; signal transduction; G-protein coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; keratinocyte migration
LTBP1negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta
LTBP2transforming growth factor beta receptor signaling pathway; protein secretion; protein targeting
LTBP3skeletal system development; transforming growth factor beta receptor signaling pathway; lung saccule development; bone morphogenesis; bone remodeling; positive regulation of bone resorption; negative regulation of chondrocyte differentiation; negative regulation of bone mineralization
LTBRinterspecies interaction between organisms; apoptotic process; signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; cellular response to mechanical stimulus; positive regulation of extrinsic apoptotic signaling pathway
LTFproteolysis; ion transport; iron ion transport; cellular iron ion homeostasis; humoral immune response; metabolic process; defense response to bacterium
LTKphosphatidylinositol 3-kinase cascade; cellular response to retinoic acid; positive regulation of neuron projection development; cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway; signal transduction; apoptotic process; protein phosphorylation
LTN1protein autoubiquitination
LUC7Lnegative regulation of striated muscle tissue development
LUC7L2-
LUMvisual perception; response to organic cyclic compound; collagen fibril organization; cartilage development; response to growth factor stimulus
LURAP1L-
LUZP1-
LUZP2-
LUZP4-
LY6K-
LY86apoptotic process; inflammatory response; humoral immune response; cell proliferation; innate immune response
LY9cell adhesion; immunoglobulin mediated immune response
LYAR-
LYG1metabolic process; peptidoglycan catabolic process; cell wall macromolecule catabolic process
LYL1blood vessel maturation; regulation of transcription, DNA-dependent; B cell differentiation; positive regulation of transcription, DNA-dependent; definitive hemopoiesis
LYNresponse to hormone stimulus; signal transduction by phosphorylation; peptidyl-tyrosine phosphorylation; response to organic cyclic compound; oligodendrocyte development; positive regulation of neuron projection development; negative regulation of intracellular protein kinase cascade; response to carbohydrate stimulus; lipopolysaccharide-mediated signaling pathway; regulation of apoptotic process; response to toxin; platelet activation; erythrocyte differentiation; T cell costimulation; cellular response to extracellular stimulus; response to insulin stimulus; regulation of mast cell activation; regulation of cell adhesion mediated by integrin; negative regulation of toll-like receptor 2 signaling pathway; negative regulation of toll-like receptor 4 signaling pathway; cellular response to heat; leukocyte migration; regulation of platelet aggregation; dendritic cell differentiation; regulation of monocyte chemotaxis; cellular response to retinoic acid; positive regulation of mast cell proliferation; negative r
LYNX1-
LYPD2-
LYPLA1lipid metabolic process; fatty acid metabolic process; small molecule metabolic process; nitric oxide metabolic process; regulation of nitric-oxide synthase activity
LYSMD1cell wall macromolecule catabolic process
LYSMD2cell wall macromolecule catabolic process
LYSMD3cell wall macromolecule catabolic process
LYSMD4cell wall macromolecule catabolic process
LYSTendosome to lysosome transport via multivesicular body sorting pathway; defense response to bacterium; defense response to protozoan; pigmentation; defense response to virus; mast cell secretory granule organization; melanosome organization; natural killer cell mediated cytotoxicity; leukocyte chemotaxis; protein transport
LYVE1cell adhesion; glycosaminoglycan catabolic process; transport; cellular component movement; cell-matrix adhesion; signal transduction; response to wounding; anatomical structure morphogenesis
LZICresponse to ionizing radiation
LZTFL1-
LZTR1regulation of transcription, DNA-dependent; anatomical structure morphogenesis
LZTS1cell cycle; regulation of transcription, DNA-dependent; transcription, DNA-dependent; transcription from RNA polymerase III promoter; transcription elongation from RNA polymerase III promoter; termination of RNA polymerase III transcription; regulation of dendrite morphogenesis; gene expression
M1AP-
M6PRendosome to lysosome transport; receptor-mediated endocytosis; transport
MAATS1-
MAB21L1multicellular organismal development; anatomical structure morphogenesis; positive regulation of cell proliferation; camera-type eye development; embryonic organ development
MAB21L2camera-type eye development; positive regulation of cell proliferation; embryonic body morphogenesis; nervous system development; multicellular organismal development
MAB21L3-
MACC1regulation of transcription, DNA-dependent; positive regulation of cell division
MACF1posttranslational protein targeting to membrane; ATP catabolic process; mesoderm formation; regulation of focal adhesion assembly; Golgi to plasma membrane protein transport; wound healing; regulation of microtubule-based process; positive regulation of Wnt receptor signaling pathway; cellular component movement; cell cycle arrest; establishment or maintenance of cell polarity; regulation of epithelial cell migration
MACROD2purine nucleoside metabolic process
MAD1L1mitotic cell cycle checkpoint; cell cycle checkpoint; M phase of mitotic cell cycle; mitotic metaphase; mitotic anaphase; mitotic telophase; mitotic prometaphase; mitotic cell cycle; mitotic cell cycle spindle assembly checkpoint; cell division
MAD2L2mitotic cell cycle spindle assembly checkpoint; DNA repair; double-strand break repair; regulation of cell growth; cell cycle; positive regulation of peptidyl-serine phosphorylation; negative regulation of protein catabolic process; DNA damage response, signal transduction resulting in transcription; positive regulation of transcription, DNA-dependent; cell division; negative regulation of mitotic anaphase-promoting complex activity; mitosis
MADCAM1embryo development; positive regulation of leukocyte migration; immune response; cell adhesion; signal transduction; aging; regulation of immune response
MADDregulation of apoptotic process; regulation of cell cycle; cell surface receptor signaling pathway; positive regulation of protein phosphorylation; activation of MAPK activity
MAEAcytoskeleton organization; cell cycle; cell adhesion; regulation of mitotic cell cycle; negative regulation of myeloid cell apoptosis; erythrocyte maturation; enucleate erythrocyte development; cell division
MAELmulticellular organismal development; synapsis; cell differentiation; negative regulation of gene expression; fertilization; spermatogenesis; male meiosis; negative regulation of apoptotic process; DNA methylation involved in gamete generation; piRNA metabolic process; gene silencing by RNA; cell morphogenesis; response to DNA damage stimulus; negative regulation of transcription from RNA polymerase II promoter; regulation of organ growth; meiotic prophase I
MAFtranscription from RNA polymerase II promoter
MAF1negative regulation of transcription from RNA polymerase III promoter; regulation of transcription, DNA-dependent
MAFAnitric oxide mediated signal transduction; positive regulation of transcription from RNA polymerase II promoter; insulin secretion; response to glucose stimulus; regulation of transcription, DNA-dependent
MAFBinner ear morphogenesis; negative regulation of erythrocyte differentiation; rhombomere 6 development; positive regulation of transcription from RNA polymerase II promoter; brain segmentation; segment specification; sensory organ development; respiratory gaseous exchange; rhombomere 5 development
MAFGin utero embryonic development; regulation of transcription, DNA-dependent; blood coagulation; adult behavior; regulation of cellular pH; regulation of cell proliferation; regulation of epidermal cell differentiation
MAGregulation of axonogenesis; negative regulation of axonogenesis; leukocyte migration; nerve growth factor receptor signaling pathway; cell adhesion; blood coagulation
MAGEA11-
MAGEB1-
MAGEB10-
MAGEB16-
MAGEB2-
MAGEB3-
MAGEB4-
MAGEC1-
MAGEC2-
MAGEC3-
MAGED1regulation of transcription, DNA-dependent; apoptotic process; induction of apoptosis by extracellular signals; regulation of apoptotic process; nerve growth factor receptor signaling pathway; negative regulation of epithelial cell proliferation
MAGED2-
MAGEE1-
MAGEE2-
MAGEF1-
MAGI1protein complex assembly; cell adhesion; cell surface receptor signaling pathway
MAGI2mitotic cell cycle arrest; positive regulation of receptor internalization; glomerular visceral epithelial cell development; SMAD protein signal transduction; negative regulation of protein kinase B signaling cascade; protein heterooligomerization; receptor clustering; negative regulation of activin receptor signaling pathway; planar cell polarity pathway involved in axis elongation; negative regulation of cell proliferation; negative regulation of cell migration; positive regulation of phosphoprotein phosphatase activity
MAGI3apoptotic process; intracellular signal transduction; interspecies interaction between organisms
MAGT1protein N-linked glycosylation; cognition; magnesium ion transport; transport
MALmembrane raft polarization; apical protein localization; myelination; cell differentiation; central nervous system development; induction of apoptosis
MALT1T cell receptor signaling pathway; positive regulation of T cell cytokine production; positive regulation of T cell activation; positive regulation of NF-kappaB transcription factor activity; positive regulation of I-kappaB kinase/NF-kappaB cascade; regulation of apoptotic process; positive regulation of phosphorylation; positive regulation of interleukin-2 production; positive regulation of protein ubiquitination; protein ubiquitination; protein oligomerization; proteolysis; anti-apoptosis; defense response; activation of NF-kappaB-inducing kinase activity; nuclear export
MAMDC2-
MAML1regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of muscle cell differentiation; protein phosphorylation; gene expression; positive regulation of myotube differentiation; myoblast differentiation; Notch signaling pathway
MAMLD1regulation of transcription, DNA-dependent; male gonad development
MAMSTRpositive regulation of myotube differentiation; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
MAN1A1metabolic process; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process
MAN1A2post-translational protein modification; cellular protein metabolic process; lung alveolus development; metabolic process; glycoprotein metabolic process; protein N-linked glycosylation via asparagine; N-glycan processing; respiratory gaseous exchange
MAN1B1protein folding; post-translational protein modification; protein N-linked glycosylation; metabolic process; protein N-linked glycosylation via asparagine; ER-associated protein catabolic process; oligosaccharide metabolic process; cellular protein metabolic process
MAN1C1metabolic process; cellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation; protein N-linked glycosylation via asparagine
MAN2A1lung alveolus development; mitochondrion organization; cellular protein metabolic process; in utero embryonic development; liver development; carbohydrate metabolic process; mannose metabolic process; N-glycan processing; post-translational protein modification; protein N-linked glycosylation via asparagine; respiratory gaseous exchange; vacuole organization
MAN2B1carbohydrate metabolic process; protein deglycosylation; protein modification process; learning or memory; mannose metabolic process
MAN2B2carbohydrate metabolic process; mannose metabolic process
MAN2C1mannose metabolic process; carbohydrate metabolic process
MANBAprotein modification process; carbohydrate metabolic process
MANEAcellular protein metabolic process; post-translational protein modification; protein N-linked glycosylation via asparagine
MANEAL-
MAOAcellular biogenic amine metabolic process; small molecule metabolic process; phenylethylamine metabolic process; serotonin metabolic process; dopamine catabolic process; neurotransmitter biosynthetic process; behavior; neurotransmitter secretion; synaptic transmission; xenobiotic metabolic process; catecholamine metabolic process; neurotransmitter catabolic process
MAOBresponse to selenium ion; response to corticosterone stimulus; response to steroid hormone stimulus; positive regulation of dopamine metabolic process; response to ethanol; small molecule metabolic process; response to drug; response to lipopolysaccharide; negative regulation of serotonin secretion; response to aluminum ion; response to toxin; xenobiotic metabolic process
MAP1A-
MAP1Bpositive regulation of axon extension; mitochondrion transport along microtubule; positive regulation of neuron differentiation; response to carbohydrate stimulus; response to mechanical stimulus; central nervous system development; synapse assembly; axonogenesis; negative regulation of microtubule depolymerization; microtubule bundle formation; neuron development; axon extension involved in development; response to axon injury; induction of synaptic plasticity by chemical substance; establishment of monopolar cell polarity; cellular process; response to insecticide; embryo development; response to peptide hormone stimulus; response to drug; response to vitamin A; negative regulation of intracellular transport; response to estradiol stimulus; response to nutrient levels; positive regulation of microtubule polymerization; developmental maturation; response to inorganic substance; dendrite development; peripheral nervous system axon regeneration
MAP1Smitochondrion transport along microtubule; nervous system development; brain development; neuron projection morphogenesis; apoptotic process; microtubule bundle formation
MAP2microtubule bundle formation; negative regulation of microtubule depolymerization; axonogenesis; central nervous system neuron development; peptidyl-threonine phosphorylation; neuron projection development; dendrite morphogenesis
MAP2K1negative regulation of cell proliferation; cell cycle arrest; mitosis; signal transduction; epidermal growth factor receptor signaling pathway; small GTPase mediated signal transduction; Ras protein signal transduction; axon guidance; Toll signaling pathway; regulation of vascular smooth muscle contraction; insulin receptor signaling pathway; response to oxidative stress; chemotaxis; cellular component movement; neuron differentiation; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; activation of MAPK activity; activation of MAPKK activity; MAPK cascade; placenta blood vessel development; TRIF-dependent toll-like receptor signaling pathway; cellular senescence; regulation of Golgi inheritance; labyrinthine layer development; stress-activated MAPK cascade; response to glucocorticoid stimulus; cell motility; neuron projection morphogenesis; response to axon injury; nerve growth factor receptor signaling pathway;
MAP2K3cardiac muscle contraction; stress-activated MAPK cascade; positive regulation of transcription, DNA-dependent; positive regulation of protein kinase activity; toll-like receptor 4 signaling pathway; innate immune response; regulation of cytokine biosynthetic process; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; Toll signaling pathway; signal transduction; inflammatory response; MyD88-independent toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; activation of MAPK activity
MAP2K4apoptotic process; cellular response to mechanical stimulus; stress-activated MAPK cascade; innate immune response; TRIF-dependent toll-like receptor signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; Toll signaling pathway; JNK cascade; signal transduction; response to stress; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; protein phosphorylation
MAP2K5negative regulation of transcription from RNA polymerase II promoter; activation of MAPK activity; protein phosphorylation; signal transduction; heart development; negative regulation of chemokine (C-X-C motif) ligand 2 production; negative regulation of cell migration involved in sprouting angiogenesis; cellular response to laminar fluid shear stress; cellular response to growth factor stimulus; ERK5 cascade; negative regulation of response to cytokine stimulus; positive regulation of protein metabolic process; positive regulation of epithelial cell proliferation; nerve growth factor receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; negative regulation of interleukin-8 biosynthetic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; negative regulation of heterotypic cell-cell adhesion; negative regulation of NF-kappaB transcription factor activity; positive regulation of
MAP2K7TRIF-dependent toll-like receptor signaling pathway; positive regulation of neuron apoptosis; innate immune response; stress-activated MAPK cascade; JNK cascade; toll-like receptor 3 signaling pathway; activation of MAPK activity; toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; apoptotic process; response to stress; signal transduction; activation of JUN kinase activity; Toll signaling pathway; toll-like receptor 1 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway
MAP3K1protein autophosphorylation; MAPK cascade; cellular response to mechanical stimulus; protein oligomerization; toll-like receptor 4 signaling pathway; positive regulation of viral transcription; wound healing; innate immune response; positive regulation of apoptotic process; camera-type eye development; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; toll-like receptor 2 signaling pathway; toll-like receptor 1 signaling pathway; negative regulation of actin filament bundle assembly; protein polyubiquitination; positive regulation of actin filament polymerization; regulation of cell migration; peptidyl-serine phosphorylation; apoptotic mitochondrial changes; Toll signaling pathway; transforming growth factor beta receptor signaling pathway; response to osmotic stress; activation of MAPKK activity; protein phosphorylation; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway
MAP3K11cell death; protein autophosphorylation; positive regulation of JNK cascade; positive regulation of neuron apoptosis; positive regulation of JUN kinase activity; cell proliferation; activation of JUN kinase activity; activation of JNKK activity; JNK cascade; microtubule-based process; protein phosphorylation; activation of MAPK activity; G1 phase of mitotic cell cycle
MAP3K12peptidyl-serine phosphorylation; protein phosphorylation; intracellular protein kinase cascade; JNK cascade; histone phosphorylation; peptidyl-threonine phosphorylation; protein autophosphorylation
MAP3K13JNK cascade; activation of MAPKK activity; positive regulation of NF-kappaB transcription factor activity; protein autophosphorylation