GoMiner    Application Build: 457     Database Build: 2011-01     Genomics and Bioinformatics Group GBG Logo

GoMiner™ is a tool for biological interpretation of 'omic' data – including data from gene expression microarrays. Omic experiments often generate lists of dozens or hundreds of genes that differ in expression between samples, raising the question

What does it all mean biologically?

To answer this question, GoMiner leverages the Gene Ontology (GO) to identify the biological processes, functions and components represented in these lists. Instead of analyzing microarray results with a gene-by-gene approach, GoMiner classifies the genes into biologically coherent categories and assesses these categories. The insights gained through GoMiner can generate hypotheses to guide additional research.

We have updated our Getting Started section with guidance on chosing between GoMiner and High-Throughput GoMiner

New Features

  • Latest !!! Remove redundancy from CIMs. Read about how RedundancyMiner can clean up redundancy in your results.
  • Latest !!! We have updated the build of the GO database.
  • Automatically create Clustered Image Maps (CIMs) from HTGM.
  • New options for adjusting reports and calculations.
  • Other Recent GoMiner Highlights...

To get started using GoMiner

GoMiner displays the genes within the framework of the Gene Ontology hierarchy in two ways

In the form of a tree, similar to that in AmiGO In the form of a 'Directed Acyclic Graph' (DAG)

Size of the box is propotional log n

Thumbnail of GoMiner's Tree View.  Click to Enlarge Thumbnail of GoMiner's DAG View.  Click to Enlarge

Click image to view screenshot

The program also provides:

Quantitative and statistical analysis Seamless integration with important public databases
Thumbnail of GoMiner's Data Export Format.  Click to Enlarge Thumbnail of an external tool accessible from GoMiner. Click to see an image depicting a number of such resources

Click image to view screenshot

Receive Updates

If you would like to receive the latest news about GoMiner, and the other tools and content provided by the NCI/LMP Genomics and Bioinformatics group, sign up for our announcements mailing list.

GoMiner™ is a development of the Genomics and Bioinformatics Group, Developmental Therapeutics Branch (DTB), Developmental Therapeutics Program (DTP), Center for Cancer Research (CCR), National Cancer Institute (NCI). We would like to hear from you. You can reach the team via email.

GoMiner was originally developed jointly by the Genomics and Bioinformatics Group (GBG) of LMP, NCI, NIH and the Medical Informatics and Bioimaging group of BME, Georgia Tech/Emory University. It is now maintained and under continuing development by GBG.

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