Genomics and Bioinformatics Group Genomics and Bioinformatics Group Genomics and Bioinformatics Group
Genomics and Bioinformatics Group

2010 Publication

Genomics and Bioinformatics Group
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Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors.
Cancer Res 2010, 70(20):8055-8065.
Solier S, Barb J, Zeeberg BR, Varma S, Ryan MC, Kohn KW, Weinstein JN, Munson PJ, Pommier Y.

Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons.
Mol Cancer Ther. 2010 Dec;9(12):3105-14.
Gmeiner WH, Reinhold W, Pommier Y.

Ontogenomic study of the relationship between number of gene splice variants and GO categorization.
Bioinformatics. 2010 Aug 15;26(16):1945-9. Epub 2010 Jul 8.
Kahn AB, Zeeberg BR, Ryan MC, Jamison DC, Rockoff DM, Pommier Y, Weinstein JN.

mRNA and microRNA Expression Profiles of the NCI-60 Integrated with Drug Activities.
Mol Cancer Ther May 2010 9; 1080 [Epub ahead of print]
Liu H, D'Andrade P, Fulmer-Smentek S, Lorenzi P, Kohn K, Weinstein J, Pommier Y and Reinhold W.

Exon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.
Cancer Res. 2010 Mar 15;70(6):2191-203. Epub 2010 Mar 9.
Reinhold WC, Mergny JL, Liu H, Ryan M, Pfister TD, Kinders R, Parchment R, Doroshow J, Weinstein JN, Pommier Y.

Regulation of Human Skin Pigmentation in situ by Repetitive UV Exposure: Molecular Characterization of Responses to UVA and/or UVB.
J Invest Dermatol. 2010 Feb 11. [Epub ahead of print]
Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, Kolbe L, Hearing VJ.

Multifactorial regulation of E-cadherin expression: an integrative study.
Mol Cancer Ther. 2010 Jan;9(1):1-16. Epub 2010 Jan 6.
Reinhold WC, Reimers MA, Lorenzi P, Ho J, Shankavaram UT, Ziegler MS, Bussey KJ, Nishizuka S, Ikediobi O, Pommier YG, Weinstein JN.


Genomics and Pharmacology  Facility
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