GBG logo CellMiner Build:1.0 Genomics and Bioinformatics Group

CellMiner™ is a web application that facilitates retreival and integration of the various molecular data sets generated by the Genomics & Bioinformatics Group, LMP, CCR, NCI and its many collaborators. Subsequent builds will include additional molecular data sets and integrative capabilities. Data included in CellMiner is from:
     •    The NCI-60, a panel of 60 diverse human cancer cell lines used by the Developmental Therapeutics Program of the U.S. National Cancer Institute to screen >100,000 compounds and natural products since 1990.
     •    The DU145/RC0.1 prostate cancer cell line pair. RC0.1 is a derivative of DU145 selected for resistance to the topoisomerase I inhibitor camptothecin.

CellMiner was developed as a companion for the Spotlight on Molecular Profiling series, which we launched with 3 articles in Molecular Cancer Therapeutics in November 2006.

New paper DNA fingerprinting of the NCI-60 cell line panel (Lorenzi et al, 2009) To download the DNA fingerprinting data for the NCI-60 click here or to learn how to compare your DNA fingerprints to those of the NCI-60, click here.

How to find the information you need in CellMiner

Links
For other bioinformatic tools and database resources from GBG go to the Discover website home page.
For additional drug, dataset and molecular target data see the NCI Developmental Therapeutics Program site.

CellMiner Development Team

Uma Shankavaram, William Reinhold, Margot Sunshine, Sudhir Varma, David Kane, Hong Cao, Ari Kahn, Gabriel Eichler, Sohana Chowdhury, Mike Walsh, John Weinstein


If you would like to receive the latest news about CellMiner, and the other tools and content provided by the NCI/LMP Genomics and Bioinformatics group, sign up for our announcements mailing list.

CellMiner™ is a development of the Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology (LMP), Center for Cancer Research (CCR), National Cancer Institute (NCI). Please email us with any problems, questions or feedback on the tool.

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