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Regulation of hypoxia-responsive genes
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Regulation of hypoxia-responsive genes

MIM of static hypoxia

Kurt W. Kohn, Joseph Riss, Mirit Aladjem and Yves Pommier

Implemented by : Margot Sunshine, Hong Cao and David Kane

To read the original paper describing this map and the symbols used, click

This molecular interaction map depicts the regulatory network that inhibits transcription in the presence of normal oxygen levels and switches HIF-mediated transcription on when oxygen levels are reduced. An analysis of the hypoxia-induced regulatory switch can be accessed here

A glossary of the molecules participating in the hypoxia-induced response is available here
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