Regulation of hypoxia-responsive genesKurt W. Kohn, Joseph Riss, Mirit Aladjem and Yves Pommier Implemented by : Margot Sunshine, Hong Cao and David Kane To read the original paper describing this map and the symbols used, click here.This molecular interaction map depicts the regulatory network that inhibits transcription in the presence of normal oxygen levels and switches HIF-mediated transcription on when oxygen levels are reduced. An analysis of the hypoxia-induced regulatory switch can be accessed here A glossary of the molecules participating in the hypoxia-induced response is available here |
This website is a development of the Genomics and Pharmacology Facility, Developmental Therapeutics Branch (DTB), Center for Cancer Research (CCR), National Cancer Institute (NCI). |
If you have questions or comments about this site, please send them to: webadmin@discover.nci.nih.gov. |