Mission and Central activities:
The Genomic and Bioinformatics Group is run under the auspices of Dr. Yves Pommier. The site was originally developed by Dr. John Weinstein. It is currently being supervised by Mr. William Reinhold.
The GBG's mission is to manage and assess molecular interaction data obtained through multiple platforms,
increase the understanding of the effect of those interactions on the chemosensitivity of cancer, and create tools
that will facilitate that process. Translation of that information will be directed towards the recognition of
diagnostic and therapeutic cancer biomarkers, and directed cancer therapy.
Freely available for public use are our professional grade Miner Suite bioinformatics software package, as well as
our characterization and annalysis of the NCI-60 cancer cell lines, the DNA, RNA, protein, epigenetic and pharmacological
levels (accessible through CellMiner).