Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity.
Mol Cancer Ther. 2009 Jul;8(7):1878-84. Epub 2009 Jul 7
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database.
Mol Cancer Ther. 2009 Jul;8(7):2057-66. Epub 2009 Jul 7
CellMiner: a relational database and query tool for the NCI-60 cancer cell lines.
BMC Bioinformatics. 2009 Jun 23;10:277
DNA fingerprinting of the NCI-60 cell line panel.
Mol Cancer Ther. 2009 Apr;8(4):713-24
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
Mol Cancer Ther. 2008 Oct;7(10):3123-8
SpliceCenter: a suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies.
BMC Bioinformatics. 2008 Jul 18;9:313
In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Mol Cancer Ther. 2008 Jun 4. [Epub ahead of print]
A Postgenomic Visual Icon.
Science. 2008 March 28;319(5871):1772
The EDGE hypothesis: Epigenetically directed genetic errors in repeat-containing proteins (RCPs) involved in evolution, neuroendocrine signaling, and cancer
Front Neuroendocrinol. 2008 Jan 8
VennMaster: Area-proportional Euler diagrams for functional GO analysis of microarrays.
BMC Bioinformatics. 2008 Jan 29;9(1):67
Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National CancerInstitute Anticancer Drug Screen.
Cancer Res. 2008 Jan 15;68(2):415-24.
Predicting cisplatin and trabectedin drug sensitivity in ovarian and colon cancers.
Mol Cancer Ther. 2008 Jan;7(1):10-8.
MicroRNAs modulate the chemosensitivity of tumor cells.
Mol Cancer Ther. 2008 Jan;7(1):1-9.
UPLC-ESI-TOFMS-Based Metabolomics and Gene Expression Dynamics Inspector Self-Organizing Metabolomic Maps as Tools for Understanding the Cellular Response to Ionizing Radiation.
Anal Chem. 2008 Jan 4
Opportunities and challenges in ovarian cancer research, a perspective from the 11th Ovarian cancer action/HHMT Forum, Lake Como, March 2007
Gynecol Oncol. 2007 Dec 19
The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data
Genome Biol. 2007 Sep 10;8(9):R187
A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
Proc Natl Acad Sci U S A. 2007 Jul 31
AffyProbeMiner: a web resource for computing or retrieving accurately redefined Affymetrix probe sets
Bioinformatics. 2007 Jul 27
Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition
Oncogene. 2007 Jul 9
MicroRNA expression profiles for the NCI-60 cancer cell panel
Mol Cancer Ther 2007;6(5):1483-91
Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
Mol Cancer Ther 2007;6(3):820-32
Multiplexing siRNAs to compress RNAi-based screen size in human cells
Nucleic Acids Res. 2007 Mar 28
SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis
BMC Bioinformatics. 2007 Mar 5;8(1):75
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells
Mol Cancer Ther. 2007 Feb;6(2):391-403.
Spotlight on molecular profiling: 'integromic' analysis of the NCI-60 cancer cell lines
Mol Cancer Ther. 2006;5:2601-2605
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
Mol Cancer Ther. 2006;5:2606-2612
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells
Mol Cancer Ther. 2006;5:2613-2623
Depicting combinatorial complexity with the molecular interaction map notation
Mol Syst Biol. 2006;2:51. Epub 2006 Oct 3.
Activation of Aminoflavone (NSC 686288) by a Sulfotransferase Is Required for the Antiproliferative Effect of the Drug and for Induction of Histone γ-H2AX
Cancer Res. 2006 Oct 1;66(19):9656-64.
Cancers as Wounds that Do Not Heal: Differences and Similarities between Renal Regeneration/Repair and Renal Cell Carcinoma
Cancer Res. 2006 Jul 15;66(14):7216-24.
Agile methods in biomedical software development: a multi-site experience report
BMC Bioinformatics. 2006 May 30;7(1):273
Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling.
Genome Res. 2006 Jun;16(6):796-803.
Chk2 Molecular Interaction Map and Rationale for Chk2 Inhibitors
Clin Cancer Res. 2006 May 1;12(9):2657-61.
Selective Toxicity of NSC73306 in MDR1-Positive Cells as a New Strategy to Circumvent Multidrug Resistance in Cancer
Cancer Res. 2006 May 1;66(9):4808-4815.
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel
Mol Cancer Ther. 2006 Apr;5(4):853-67.
AbMiner: A bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies
BMC Bioinformatics 2006, 7:192 doi:10.1186/1471-2105-7-192
Comparison of methods for sequential screening of large compound sets
Comb Chem High Throughput Screen. 2006 Feb;9(2):115-22.
Biomarkers in Cancer Staging, Prognosis and Treatment Selection
Nature Reviews Cancer 5, 845-856 (2005)
The p53 Tumor Suppressor Network Is a Key Responder to Microenvironmental Components of Chronic Inflammatory Stress
Cancer Res. 2005 Nov 15;65(22):10255-10264.
Molecular Interaction Maps of Bioregulatory Networks: A General Rubric for Systems Biology
Mol Biol Cell. 2005 Nov 2; [Epub ahead of print]
Nova regulates brain-specific splicing to shape the ynapse
Nat Genet. 2005 Aug;37(8):844-52. Epub 2005 Jul 24
High-Throughput GoMiner, an 'industrial-strength' integrative Gene Ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID)
BMC Bioinformatics. 2005 Jul 5;6(1):168.
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
BMC Bioinformatics. 2005 Jul 1;6(1):166.
Three microarray platforms: an analysis of their concordance in profiling gene expression
BMC Genomics. 2005 May 5;6(1):63.
Workshop on Cancer Biometrics: Identifying Biomarkers and Surrogates of Cancer in Patients: A Meeting Held at the Masur Auditorium, National Institutes of Health.
J Immunother. 2005 March/April;28(2):79-119.
Karyotypic "state" as a potential determinant for anticancer drug discovery
Proc Natl Acad Sci U S A. 2005 Feb 9; [Epub ahead of print]
Identification of non-cross-resistant platinum compounds with novel cytotoxicity profiles using the NCI anticancer drug screen and clustered image map visualizations
Crit Rev Oncol Hematol. 2005 Jan;53(1):25-34.