Publications

Before 2000

Selected Articles from the Genomics and Pharmacology Facility: Pre-1999 (followed by full bibliography)

  1. MedMiner: An internet tool for filtering and organizing biomedical information, with application to gene expression profiling.
    BioTechniques. 1999; 27: 1210-1217
    by Tanabe, L., Smith, L.H., Lee, J.K., Scherf, U., Hunter, L., and Weinstein, J.N.

  2. The Complexity of Radiation Stress Responses: Analysis by Informatics and Functional Genomics Approaches
    Gene Expr 1999;7(4-6):387-400
    by Fornace AJ Jr, Amundson SA, Bittner M, Myers TG, Meltzer P, Weinsten JN, Trent J.

  3. Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin
    Mol Cell Biol 1999 Mar;19(3):1673-85
    by Carrier F, Georgel PT, Pourquier P, Blake M, Kontny HU, Antinore MJ, Gariboldi M, Myers TG, Weinstein JN, Pommier Y, Fornace AJ Jr.

  4. Molecular interaction map of the mammalian cell cycle control and DNA repair systems
    Mol Biol Cell. 1999 Aug;10(8):2703-34.
    by Kohn KW.

  5. Weinstein, J.N., Myers, T.G., O'Connor, P.M., Friend, S.H., Fornace, A.J., Kohn, K.W., Fojo, T., Bates, S.E., Rubinstein, L.V., Anderson, N.L., Buolamwini, J.K., van Osdol, W.W., Monks, A.P., Scudiero, D.A., Sausville, E.A., Zaharevitz, D.W., Bunow, B., Viswanadhan, V.N., Johnson, G.S., Wittes, R.E., and Paull, K.D. An information-intensive approach to the molecular pharmacology of cancer. Science 1997; 275:343-349. Abstract

  6. Weinstein, J.N., Fishing expeditions, Science 1998; 282: 627-628 ( in Genome issue). Abstract

  7. Shi, L.M., Fan, Y., Myers, T.G., and Weinstein, J.N. Genetic function approximation in the molecular pharmacology of cancer. Symp. Intl Congress on Neural Networks, 1997; 1.

  8. Li, G., Waltham, M., Unsworth, E., Treston, A., Anderson, N.L., and Weinstein, J.N. Rapid protein identification from two-dimensional polyacrylamide gels by MALDI mass spectrometry. Electrophoresis 1997; 18:391-402..

  9. Myers, T.G., Waltham, M., Li, G., Buolamwini, J.K., Scudiero, D.A., Rubinstein, L.V., Paull, K.D., Sausville, E.A., and Anderson, N.L., and Weinstein, J.N. A protein expression database for the molecular pharmacology of cancer. Electrophoresis 1997; 18:647-653.

  10. O'Connor, P.M., Jackman, J., Bae, I., Myers, T.G., Fan, S., Scudiero, D.A., Monks, A., Sausville, E.A., Weinstein, J.N., Friend, S., Fornace, A.J., Jr., and Kohn, K.W. Characterization of the p53 tumor suppressor pathway in the NCI anticancer drug screen cell lines and relationships with chemosensitivity, Cancer Research, 1997; 57: 4285-4300. Abstract

  11. Burke, H.B., Goodman, P.H., Rosen, D.B., Weinstein, J.N., Hellier, J.H., Winchester, D.P., Harrell, F.E., Marks, J.R., Bostwick, D.G., Osteen, R.T., Zincke, H., and Henson, D.E. Improving cancer survival prediction accuracy. Cancer 1997; 79: 857-862.

  12. Wosikowski, K., Schuurhuis, D., Johnson, K., Paull, K.D., Myers, T.G., Weinstein, J., and Bates, S.E. Use of EGF receptor, c-erbB2 and TGF a gene expression profiles in the National Cancer Institute anticancer drug screen to identify EGF receptor and c-erbB2 pathway inhibitors. J. Natl. Cancer Inst., 1997; 89: 1505-1515.

  13. Weinstein, J.N., Myers, T.G., O'Connor, P.M., Friend, S.H., Fornace, A.J., Kohn, K.W., Fojo, T., Bates, S.E., Rubinstein, L.V., Anderson, N.L., Buolamwini, J.K., van Osdol, W.W., Monks, A.P., Scudiero, D.A., Sausville, E.A., Zaharevitz, D.W., Bunow, B., Viswanadhan, V.N., Johnson, G.S., Wittes, R.E., and Paull, K.D. An information-intensive approach to the molecular pharmacology of cancer. Science 1997; 275:343-349.

  14. Shi, L.M., Fan, Y., Myers, T.G., Waltham, M., Paull, K.D., and Weinstein, J.N. Mining the anticancer activity database generated by the U.S. National Cancer Institute's drug discovery program using statistical and artificial intelligence techniques, Mathematical Modeling and Scientific Computing 1998; 38:189-199.

  15. Shi, L.M., Myers, T.G., Fan, Y., O'Connor, P.M., Paull, K.D., Friend, S.H., and Weinstein, J.N. Mining the NCI  anticancer drug discovery database: Cluster analysis of ellipticine analogs with p53-inverse and central nervous system-selective patterns of activity. Molecular Pharmacology 1998; 53: 241-251.

  16. Shi, L.M., Fan, Y., Myers, T.G., Paull, K.D., and Weinstein, J.N. Mining the NCI anticancer drug discovery databases: Genetic function approximation for the quantitative structure-activity relationship study of anticancer ellipticine analogs. J. Chem. Inf. Comput. Sci. 1998; 38: 189-199.

  17. Fan, Y., Weinstein, J.N., Kohn, K.W., Shi, L.M., and Pommier, Y. Molecular modeling studies of the DNA - topoisomerase I ternary cleavable complex with camptothecin. J. Med. Chem. 1998; 41: 2216-2226.