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CellMinerCDB

CellMinerCDB enables exploration and analysis of cancer cell line pharmacogenomic data across different sources. If publishing results based on this site, please cite: Luna A, Elloumi F, Varma S et al. Nucleic Acids Res. 2021 Jan 8.


Plot point tooltips provide additional information.

Data type Abbreviation Identifier ID
Drug activity act drug NSC or name
DNA Copy Number cop gene name
DNA Mutation mut gene name
DNA Methylation 450K met gene name
DNA Methylation 850K mth gene name
Body DNA Methylation 850K bmt gene name
DNA Methylation RRBS rrb gene name
Microarray RNA Expression using z-score exp gene name
Microarray RNA Expression using Avg.log2 xai gene name
RPLA Protein pro protein/gene name
MicroRNA mir microRNA ID
Miscellaneous phenotypic mda Miscellaneous phenotypic name
SWATH-MS Protein swa protein/gene name
RNA-seq Expression using log2.FPKM+1 xsq gene name
Crispr cri gene name
Metabolomics mtb metabolite
Histone H3K27ac his gene name
Histone H3K4me3 hs4 gene name
Surface Receptor Protein sur protein/gene name

Pattern comparison results are computed with respect to that data defined and shared by both the x and y-axis inputs.


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Table of Contents

Introduction

CellMinerCDB is an interactive web application that simplifies access and exploration of cancer cell line pharmacogenomic data across different sources (see Metadata section for more details). Navigation in the application is done using main menu tabs (see figure below). It includes 6 tabs: Univariate Analyses, Multivariate Analysis, Metadata, Search, Help and Video tutorial. Univariate Analyses is selected by default when entering the site. Each option includes a side bar menu (to choose input) and a user interface output to display results. Analysis options are available on the top for both the Univariant Analysis and Regression model tabs (see sub-menu on figure). The sub-menu first option result is displayed by default (Figure 1).