2020-Current

2025

Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma
2025 June 21
Anjali Dhall, Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Lauren Escobedo, Yilun Sun, Mirit I. Aladjem, Christophe E. Redon, Nitin Roper, William C. Reinhold, Jaydira Del Rivero, and Yves Pommier

Beyond the Promoter: Total MGMT Gene Methylation Modulates Response to DNA-Alkylating Agents in Glioma
2025 June 4
Nicole J. Briceno, Jinkyu Jung, Aiguo Li, Chunzhang Yang, Mioara Larion, Lorinc S. Pongor, Fathi Elloumi, Sudhir Varma, William C. Reinhold, Yves Pommier, Mark R. Gilbert, and Orieta Celiku

2024

A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples
2024 August 20
Yasuhiro Arakawa, Fathi Elloumi, Sudhir Varma, Prashant Khandagale, Ukhyun Jo, Suresh Kumar, Nitin Roper, William C. Reinhold, Robert W. Robey, Naoko Takebe, Michael M. Gottesman, Craig J. Thomas, Valentina Boeva, Alfredo Berruti, Andrea Abate, Mariangela Tamburello, Sandra Sigala, Constanze Hantel, Isabel Weigand, Margaret E. Wierman, Katja Kiseljak-Vassiliades, Jaydira Del Rivero, and Yves Pommier

Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4
2024 July 23
Makito Mizunuma, Christophe E. Redon, Liton Kumar Saha, Andy D. Tran, Anjali Dhall, Robin Sebastian, Daiki Taniyama, Michael J. Kruhlak, William C. Reinhold, Naoko Takebe, and Yves Pommier

Sarcoma CellminerCDB: A tool to interrogate the genomic and functional characteristics of a comprehensive collection of sarcoma cell lines
2024 April 15
Camille Tlemsani; Christine M. Heske; Fathi Elloumi; Lorinc Pongor; Prashant Khandagale; Sudhir Varma; Paul S. Meltzer; Javed Khan; William C. Reinhold; Yves Pommier

Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
2024 January 24
Takashi Furusawa, Thorkell Andresson, Thomas J. Meyer, Yves Pommier, Renzo Cavero, William Reinhold, Oliver Hartmann,Yue Liu, Haojian Li, Xia Xu,Olivia White,Myriem Boufraqech, Markus E. Diefenbacher, and Urbain Weyemi

2023

Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets
2023 August 22
Rui Sun, Weigang Ge, Yi Zhu, Azin Sayad, Augustin Luna, Mengge Lyu, Shuang Liang, Luis Tobalina, Vinodh N. Rajapakse, Chenhuan Yu, Huanhuan Zhang, Jie Fang, Fang Wu, Hui Xie, Julio Saez-Rodriguez, Huazhong Ying, William C. Reinhold, Chris Sander, Yves Pommier, Benjamin G. Neel, Ruedi Aebersold, and Tiannan Guo

CellMinerCDB: NCATS is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations
2023 May 4
William C. Reinhold, Kelli Wilson, Fathi Elloumi, Katie R. Bradwell, Michele Ceribelli, Sudhir Varma, Yanghsin Wang, Damien Duveau, Nikhil Menon, Jane Trepel, Xiaohu Zhang, Carleen Klumpp-Thomas, Samuel Michael, Paul Shinn, Augustin Luna, Craig Thomas, and Yves Pommier

2022

Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation
2022 November 18
Lorinc S Pongor, Camille Tlemsani, Fathi Elloumi, Yasuhiro Arakawa, Ukhyun Jo, Jacob M Gross, Sara Mosavarpour, Sudhir Varma, Rahul K Kollipara, Nitin Roper, Beverly A Teicher, Mirit I Aladjem, William C. Reinhold, Anish Thomas, John D Minna, Jane E Johnson, Yves Pommier

Artificial intelligence platform, RADR®, aids in the discovery of DNA damaging agent for the ultra-rare cancer Atypical Teratoid Rhabdoid Tumors
2022 October 11
Joseph McDermott, Drew Sturtevant, Umesh Kathad, Sudhir Varma, Jianli Zhou, Aditya Kulkarni, Neha Biyani, Caleb Schimke, William C. Reinhold, Fathi Elloumi, Peter Carr, Yves Pommier and Kishor Bhatia

2021

CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics
2021 January 08
Nucleic Acids Research, Volume 49, Issue D1, 8 January 2021, Pages D1083-D1093
Augustin Luna, Fathi Elloumi, Sudhir Varma, Yanghsin Wang, Vinodh N Rajapakse, Mirit I Aladjem, Jacques Robert, Chris Sander, Yves Pommier, William C Reinhold

R-Loop-Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin
2021 May 28
Maryam Safari, Thomas Litman, Robert W. Robey, Andrés Aguilera, Arup R. Chakraborty, William C. Reinhold, Agnes Basseville, Lubov Petrukhin, Luigi Scotto, Owen A. O'Connor, Yves Pommier, Antonio T. Fojo, and Susan E. Bates

Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines
2021 March 06
Suleyman Vural, Alida Palmisano , William C. Reinhold, Yves Pommier, Beverly A. Teicher and Julia Krushkal

2020

Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets
2020 June 25
Julia Krushkal , Thomas Silvers, William C. Reinhold, Dmitriy Sonkin, Suleyman Vural, John Connelly, Sudhir Varma, Paul S. Meltzer, Mark Kunkel, Annamaria Rapisarda, David Evans, Yves Pommier and Beverly A. Teicher

Candidate biomarker assessment for pharmacological response
2020 July 8
William C. Reinhold, Fathi Elloumi, Sudhir Varma, Jacques Robert, Gordon B. Mills, Yves Pommier

Association of Independent Prognostic Factors and Treatment Modality With Survival and Recurrence Outcomes in Breast Cancer
2020 July 9
Dat Nguyen, John Yu, William C. Reinhold and Sherry X. Yang

Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
2020 September 3
Robin Sebastian, Eri K. Hosogane, Eric G. Sun, Andy D. Tran, William C. Reinhold, Sandra Burkett, David M. Sturgill, Prabhakar R. Gudla, Yves Pommier, Mirit I. Aladjem and Philipp Oberdoerffer

SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures
2020 October 20
Camille Tlemsani, Lorinc Pongor, Fathi Elloumi, Luc Girard, Kenneth E. Huffman, Nitin Roper, Sudhir Varma, Augustin Luna, Vinodh N. Rajapakse, Robin Sebastian, Kurt W. Kohn, Julia Krushkal, Mirit I. Aladjem, Beverly A. Teicher, Paul S. Meltzer, William C. Reinhold, John D. Minna, Anish Thomas and Yves Pommier