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BMN-673 enantiomer

Key Value
Synonyms: 1207456-01-6
BMN 673
BMN-673
TALAZOPARIB
UNII-9QHX048FRV
765396
727125
BMN-673 (RACEMATE)
LT-00673
BMN-673 (RACEMIC)
767125
National Service Center# (NSC#):1,2 767533, 767125, 765396
CAS#: NA
PubChem Substance#: 440798925
PubChem Compound#: 135742498
Mechanism of Action: PARP1
Status: Clinical trial
Molecular Formula: C19H14F2N6O
Smiles: Cn1ncnc1[C@H]2[C@@H](Nc3cc(F)cc4C(=O)NN=C2c34)c5ccc(F)cc5

BMN-673 enantiomer is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.

Click Here to Access CellMinerCDB

BMN-673 enantiomer is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.

Click Here to Access CellMiner (NCI-60)

If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.

Available Data

Visit CellMinerCDB to interactively explore available pharmacogenomics data for BMN-673 enantiomer.

Visit CellMiner (NCI-60) to explore NCI-60 related analysis for BMN-673 enantiomer.

BMN-673 enantiomer is available in the following datasets
NCI60 HTS384 NCI60 GDSC-MGH-Sanger GDSC1 drugs GDSC2 drugs CCLE-Broad-MIT CTRP-Broad-MIT NCI-DTP SCLC PRISM-Broad-MIT NCI60-DTP Almanac NCATS IC50 NCATS AUC
765396
727125
767125
765396
767125
BMN-673 Talazoparib Talazoparib NA NA 765396
767125
767533
talazoparib NA talazoparib talazoparib
1 NSC#: Originally known as Cancer Chemotherapy National Service Center number, the NSC# is an identifying number assigned by NCI-DTP to an agent or product (e.g. small molecule or biological agent).
2 Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.

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