Cobimetinib (isomer 1)
| Key | Value |
|---|---|
| Synonyms: | COBIMETINIB (ISOMER 1) GDC-0623 HY-15610 GDC-0973 R-7420 RG-7420 XL-518 XL-518 (ISOMER 1) XL-518 (ISOMER 2) A-1180 COBIMETINIB (ISOMER 2) GDC-0973 RG-7421 RG-7421 XL-518 ENANTIOMER COBIMETINIB COBIMETINIB ENANTIOMER 778590 768068 |
| National Service Center# (NSC#):1,2 | 778590 |
| CAS#: | NA |
| PubChem#: | NA |
| Mechanism of Action: | PK:MAP2K,MAP2K1 |
| Status: | FDA approved |
| Molecular Formula: | C16H14FIN4O3 |
| Smiles: | OCCONC(=O)c1ccc2cncn2c1Nc3ccc(I)cc3F |
Cobimetinib (isomer 1) is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.
Click Here to Access CellMinerCDB
Cobimetinib (isomer 1) is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.
Click Here to Access CellMiner (NCI-60)
If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.
Available Data
Visit CellMinerCDB to interactively explore available pharmacogenomics data for Cobimetinib (isomer 1).
Visit CellMiner (NCI-60) to explore NCI-60 related analysis for Cobimetinib (isomer 1).
| NCI60 | GDSC-MGH-Sanger | GDSC1 drugs | GDSC2 drugs | CCLE-Broad-MIT | CTRP-Broad-MIT | NCI-DTP SCLC | PRISM-Broad-MIT | NCI60-DTP Almanac |
|---|---|---|---|---|---|---|---|---|
| 778590 | NA | NA | NA | NA | NA | NA | cobimetinib | NA |
2 Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.
