Docetaxel

Key	Value
Synonyms:	114977-28-5 DOCETAXEL DOCETAXEL ANHYDROUS DOCETAXOL TAXOTERE 759850 628503
National Service Center# (NSC#):^1,2	759850, 628503
CAS#:	148408666
PubChem Substance#:	144076180
PubChem Compound#:	9877265
Mechanism of Action:	TUBB\|Tu-stab
Status:	FDA approved
Molecular Formula:	C43H53NO14
Smiles:	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]3(C)C2[C@H](OC(=O)c4ccccc4)[C@]5(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c6ccccc6)C(=C([C@@H](O)C3=O)C5(C)C)C

Docetaxel is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.

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Docetaxel is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.

Click Here to Access CellMiner (NCI-60)

If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.

Available Data

Visit CellMinerCDB to interactively explore available pharmacogenomics data for Docetaxel.

Visit CellMiner (NCI-60) to explore NCI-60 related analysis for Docetaxel.

Docetaxel is available in the following datasets
NCI60	HTS384 NCI60	GDSC-MGH-Sanger	GDSC1 drugs	GDSC2 drugs	CCLE-Broad-MIT	CTRP-Broad-MIT	NCI-DTP SCLC	PRISM-Broad-MIT	NCI60-DTP Almanac	NCATS IC50	NCATS AUC
759850 628503	NA	Docetaxel Docetaxel_NSC_628503	Docetaxel	Docetaxel_1007 Docetaxel_1819	NA	docetaxel	628503	docetaxel	Available	docetaxel	docetaxel

¹ NSC#: Originally known as Cancer Chemotherapy National Service Center number, the NSC# is an identifying number assigned by NCI-DTP to an agent or product (e.g. small molecule or biological agent).
² Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.