Lificguat

Key	Value
Synonyms:	LIFICGUAT 728165 170632-47-0 LIFICIGUAT YC 1 YC-1 LIFICGUAT, LIFICGUAT YC1 5-[1-(PHENYLMETHYL)-1H-INDAZOL-3-YL]-2-FURANMETHANOL 81560 HY-14927 LIFICIGUAT, YC-1 2-FURANMETHANOL, 5-[1-(PHENYLMETHYL)-1H-INDAZOL-3-YL]- 3-(5'-HYDROXYMETHYL-2'-FURYL)-1-BENZYLINDAZOLE 756879 728165
National Service Center# (NSC#):^1,2	756879, 728165
CAS#:	170632470
PubChem Substance#:	440807241
PubChem Compound#:	5712
Mechanism of Action:	HYP\|HIF1\|EPAS1
Status:	Clinical trial
Molecular Formula:	C19H16N2O2
Smiles:	OCc1oc(cc1)c2nn(Cc3ccccc3)c4ccccc24

Lificguat is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.

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Lificguat is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.

Click Here to Access CellMiner (NCI-60)

If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.

Available Data

Visit CellMinerCDB to interactively explore available pharmacogenomics data for Lificguat.

Visit CellMiner (NCI-60) to explore NCI-60 related analysis for Lificguat.

Lificguat is available in the following datasets
NCI60	HTS384 NCI60	GDSC-MGH-Sanger	GDSC1 drugs	GDSC2 drugs	CCLE-Broad-MIT	CTRP-Broad-MIT	NCI-DTP SCLC	PRISM-Broad-MIT	NCI60-DTP Almanac	NCATS IC50	NCATS AUC
728165 756879	756879	NA	NA	NA	NA	NA	756879	NA	NA	lificiguat	lificiguat

¹ NSC#: Originally known as Cancer Chemotherapy National Service Center number, the NSC# is an identifying number assigned by NCI-DTP to an agent or product (e.g. small molecule or biological agent).
² Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.