RG-7388

Key	Value
Synonyms:	RG-7388 IDASANUTLIN CT-RG7388 779404
National Service Center# (NSC#):^1,2	779404
CAS#:	1229705069
PubChem Substance#:	440796068
PubChem Compound#:	53358942
Mechanism of Action:	MDM2
Status:	Clinical trial
Molecular Formula:	C31H29Cl2F2N3O4
Smiles:	COc1cc(ccc1NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]2c3cccc(Cl)c3F)c4ccc(Cl)cc4F)C(=O)O

RG-7388 is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.

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RG-7388 is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.

Click Here to Access CellMiner (NCI-60)

If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.

Available Data

Visit CellMinerCDB to interactively explore available pharmacogenomics data for RG-7388.

Visit CellMiner (NCI-60) to explore NCI-60 related analysis for RG-7388.

RG-7388 is available in the following datasets
NCI60	HTS384 NCI60	GDSC-MGH-Sanger	GDSC1 drugs	GDSC2 drugs	CCLE-Broad-MIT	CTRP-Broad-MIT	NCI-DTP SCLC	PRISM-Broad-MIT	NCI60-DTP Almanac	NCATS IC50	NCATS AUC
779404	779404	NA	NA	NA	NA	NA	NA	idasanutlin	NA	idasanutlin	idasanutlin

¹ NSC#: Originally known as Cancer Chemotherapy National Service Center number, the NSC# is an identifying number assigned by NCI-DTP to an agent or product (e.g. small molecule or biological agent).
² Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.