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WZ-4002

Key Value
Synonyms: 1213269-23-8
CHEBI:61400
UNII-6BQ432Z61M
WZ-4002
WZ4002
755927
National Service Center# (NSC#):1,2 755927
CAS#: 1213269238
PubChem Substance#: 440815479
PubChem Compound#: 44607530
Mechanism of Action: PK:YK,EGFR
Status: Clinical trial
Molecular Formula: C25H27ClN6O3
Smiles: COc1cc(ccc1Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)N4CCN(C)CC4

WZ-4002 is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.

Click Here to Access CellMinerCDB

WZ-4002 is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.

Click Here to Access CellMiner (NCI-60)

If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.

Available Data

Visit CellMinerCDB to interactively explore available pharmacogenomics data for WZ-4002.

Visit CellMiner (NCI-60) to explore NCI-60 related analysis for WZ-4002.

WZ-4002 is available in the following datasets
NCI60 HTS384 NCI60 GDSC-MGH-Sanger GDSC1 drugs GDSC2 drugs CCLE-Broad-MIT CTRP-Broad-MIT NCI-DTP SCLC PRISM-Broad-MIT NCI60-DTP Almanac NCATS IC50 NCATS AUC
NA 755927 NA NA NA NA NA 755927 WZ-4002 NA wz-4002 wz-4002
1 NSC#: Originally known as Cancer Chemotherapy National Service Center number, the NSC# is an identifying number assigned by NCI-DTP to an agent or product (e.g. small molecule or biological agent).
2 Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.

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