XK-469

Key	Value
Synonyms:	157435-10-4 NSC 697887 NSC697887 XK-469 656889 697887 698215
National Service Center# (NSC#):^1,2	656889, 697887, 698215
CAS#:	157434996
PubChem Substance#:	507364
PubChem Compound#:	54608963
Mechanism of Action:	TOP2
Status:	Clinical trial
Molecular Formula:	C17H13ClN2O4.Na
Smiles:	CC(Oc1ccc(Oc2cnc3ccc(Cl)cc3n2)cc1)C(=O)O

XK-469 is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.

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XK-469 is in CellMiner (NCI-60),a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines.

Click Here to Access CellMiner (NCI-60)

If you use content from this page, CellMinerCDB or CellMiner (NCI-60), please cite: Luna A et al. 2021. PMID: 33196823, Rajapakse VN et al. 2018. PMID: 30553813, Luna et al. 2016., PMID: 26635141, and Reinhold et al. 2012., PMID: 22802077.

Available Data

Visit CellMinerCDB to interactively explore available pharmacogenomics data for XK-469.

Visit CellMiner (NCI-60) to explore NCI-60 related analysis for XK-469.

XK-469 is available in the following datasets
NCI60	HTS384 NCI60	GDSC-MGH-Sanger	GDSC1 drugs	GDSC2 drugs	CCLE-Broad-MIT	CTRP-Broad-MIT	NCI-DTP SCLC	PRISM-Broad-MIT	NCI60-DTP Almanac	NCATS IC50	NCATS AUC
656889 697887 698215	698215	NA	NA	NA	NA	NA	698215	NA	NA	NA	NA

¹ NSC#: Originally known as Cancer Chemotherapy National Service Center number, the NSC# is an identifying number assigned by NCI-DTP to an agent or product (e.g. small molecule or biological agent).
² Most structures have a unique NSC number but over the years a small percentage of structures or agents may have been assigned more than one NSC number. In the case of salts, different salt forms (e.g. HCl, HOAc) are designated with separate NSC numbers.