CellMinerCDB

FDA Approved NSCs

Show status changed drugs only Clinical Trial NSCs
NSC Name Mechanism Current Status Previous Status
740 METHOTREXATE Df|DHFR FDA approved FDA approved
750 Busulfan A7|AlkAg FDA approved FDA approved
752 6-THIOGUANINE Ds|IMPDH2|IMPDH FDA approved FDA approved
755 6-MERCAPTOPURINE Ds|PPAT FDA approved FDA approved
762 Nitrogen mustard A7|AlkAg FDA approved FDA approved
1390 Allopurinol AM|XDH FDA approved FDA approved
3053 Actinomycin D Db FDA approved FDA approved
3088 Chlorambucil A7|AlkAg FDA approved FDA approved
3590 CALCIUM LEUCOVORIN Df FDA approved FDA approved
6396 Thiotepa A7|AlkAg FDA approved FDA approved
8806 Melphalan A7|AlkAg FDA approved FDA approved
9706 Triethylenemelamine A7|AlkAg FDA approved FDA approved
10023 Prednisone Ho FDA approved FDA approved
10973 Ethinyl estradiol Ho FDA approved FDA approved
12198 Dromostanolone Propionate Ho FDA approved FDA approved
13875 Altretamine Db|AlkAg FDA approved FDA approved
14229 Acrichine Db|AP FDA approved FDA approved
18509 Aminolevulinic acid AM FDA approved FDA approved
19893 Fluorouracil Ds|Rs|TYMS FDA approved FDA approved
23162 Nandrolone phenpropionate Ho|NonCan:Ste FDA approved FDA approved
23759 TESTOLACTONE Ho FDA approved FDA approved
24559 Mithramycin Db|Rs FDA approved FDA approved
25154 Pipobroman A7|AlkAg FDA approved FDA approved
26271 Cyclophosphamide A7|AlkAg FDA approved FDA approved
26980 Mitomycin A2 FDA approved FDA approved
27640 Floxuridine Ds|TYMS FDA approved FDA approved
32065 Hydroxyurea AM|Dr FDA approved FDA approved
34462 Uracil mustard A7|AlkAg FDA approved FDA approved
34521 Dexamethasone Decadron Ho FDA approved FDA approved
38721 Mitotane A7|Ho|AlkAg|anti-Ho|CYP11A1 FDA approved FDA approved
45388 DACARBAZINE A7|AlkAg FDA approved FDA approved
45923 Methoxsalen Db FDA approved FDA approved
49842 Vinblastine TUBB|Tu-frag FDA approved FDA approved
59687 Acetalax NonCan:Cath FDA approved FDA approved
63878 Cytarabine Ds FDA approved FDA approved
66847 Thalidomide Ang|Immunomodulatory FDA approved FDA approved
67574 Vincristine TUBB|Tu-frag FDA approved FDA approved
71423 Megestrol acetate Ho|PGR FDA approved FDA approved
75520 tfdu TYMS FDA approved FDA approved
77213 Procarbazine A7|AlkAg FDA approved FDA approved
79037 Lomustine A6|AlkAg FDA approved FDA approved
79269 Vistonuridine TUBB|FU-Antidote FDA approved FDA approved
82151 Daunorubicin TOP2 FDA approved FDA approved
83142 Daunorubicin TOP2 FDA approved FDA approved
85998 STREPTOZOCIN A7|AlkAg FDA approved FDA approved
88536 Calusterone Ho FDA approved FDA approved
89201 Estramustine A7|TUBB|AlkAg FDA approved FDA approved
90636 Vinblastine TUBB|Tu-frag FDA approved FDA approved
92339 Fluphenazine NonCan:Psy FDA approved FDA approved
92859 Arsenic trioxide Apo FDA approved FDA approved
95100 Digoxin NonCan:CardG FDA approved FDA approved
102816 AZACITIDINE DNMT FDA approved FDA approved
105014 Cladribine Ds|ADA FDA approved FDA approved
105024 Mithramycin Db|Rs FDA approved FDA approved
109229 Asparaginase AM|Pi FDA approved FDA approved
109724 Ifosfamide A7|AlkAg FDA approved FDA approved
109929 Asparaginase AM|Pi FDA approved FDA approved
113891 Mesna FDA approved FDA approved
117186 Acetalax NonCan:Cath FDA approved FDA approved
118218 Fludarabine Ds|AM|Dr|STAT1 FDA approved FDA approved
119875 Cisplatin A7|AlkAg FDA approved FDA approved
122758 Isotretinoin Ho|RXR|Differentiator FDA approved FDA approved
122819 Teniposide TOP2 FDA approved FDA approved
123127 Doxorubicin TOP2 FDA approved FDA approved
124463 Fludarabine Ds|AM|Dr|STAT1 FDA approved FDA approved
125066 Bleomycin Db FDA approved FDA approved
125973 Paclitaxel TUBB|Tu-stab FDA approved FDA approved
127716 DECITABINE AM|DNMT FDA approved FDA approved
134727 Mitomycin A2 FDA approved FDA approved
138783 Bendamustine A2|A6|AlkAg FDA approved FDA approved
141540 Etoposide TOP2 FDA approved FDA approved
141633 Homoharringtonine Apo|Ang|Pi FDA approved FDA approved
143020 Mithramycin Db|Rs FDA approved FDA approved
148958 Tegafur Df FDA approved FDA approved
157035 Parthenolide Apo FDA approved FDA approved
169780 Dexrazoxane TOP2|NonCan:Cardioprotective FDA approved FDA approved
177023 Levamisole hydrochloride FDA approved FDA approved
180973 Tamoxifen Ho|SERM FDA approved FDA approved
218321 PENTOSTATIN Ds|AM|ADA FDA approved FDA approved
226080 RAPAMYCIN PK:STK,MTOR FDA approved FDA approved
241240 Carboplatin A7|AlkAg FDA approved FDA approved
246131 Valrubicin TOP2 FDA approved FDA approved
256439 Idarubicin TOP2 FDA approved FDA approved
256942 Epirubicin TOP2 FDA approved FDA approved
266046 Oxaliplatin A7|AlkAg FDA approved FDA approved
279836 MITOXANTRONE TOP2 FDA approved FDA approved
287459 Cytarabine Ds FDA approved FDA approved
296961 Amifostine RP FDA approved FDA approved
301739 Mitoxantrone TOP2 FDA approved FDA approved
312887 Fludarabine Ds|AM|Dr|STAT1 FDA approved FDA approved
362856 Temozolomide A7|AlkAg FDA approved FDA approved
369100 Imiquimod AM|TLR7|ImmuneResMod FDA approved FDA approved
409962 Carmustine A7|AlkAg FDA approved FDA approved
526598 Mithramycin Db|Rs FDA approved FDA approved
606698 Rapamycin PK:STK,MTOR FDA approved FDA approved
606869 Clofarabine Ds FDA approved FDA approved
608000 Tamibarotene RXR FDA approved FDA approved
608210 Vinorelbine TUBB|Tu-frag FDA approved FDA approved
609699 Topotecan TOP1 FDA approved FDA approved
613327 Gemcitabine Ds FDA approved FDA approved
613680 Toremifene Ho FDA approved FDA approved
614826 Bisacodyl, active ingredient of Viraplex NonCan:Cath FDA approved FDA approved
616348 Irinotecan TOP1 FDA approved FDA approved
628503 Docetaxel TUBB|Tu-stab FDA approved FDA approved
630176 Depsipeptide HDAC FDA approved FDA approved
632307 Cetuximab Ab FDA approved FDA approved
633782 Simvastatin AM|NonCan:Chol FDA approved FDA approved
639186 Raltitrexed Ds|DHFR|TYMS FDA approved FDA approved
648766 Trabectedin A2 FDA approved FDA approved
656576 Midostaurin PK:PRKCA,STK FDA approved FDA approved
673596 7-Ethyl-10-hydroxycamptothecin TOP1 FDA approved FDA approved
676879 Phenothiazine, 2-azido-10-[4-(4-methyl-1-piperazinyl)butyl]-, difumarate NonCan:Psy FDA approved FDA approved
681239 Bortezomib PSM FDA approved FDA approved
683863 Irofulven Apo|AlkAg|RDI FDA approved FDA approved
683864 Temsirolimus PK:STK,MTOR FDA approved FDA approved
685701 Flurbiprofen FDA approved FDA approved
686673 Nelarabine Ds FDA approved FDA approved
688097 Trastuzumab Ab FDA approved FDA approved
697979 Denileukin Diftitox Ontak IL FDA approved FDA approved
698037 Pemetrexed Df|AM|GARTF|DHFR FDA approved FDA approved
701852 Vorinostat HDAC FDA approved FDA approved
702294 Estramustine A7|TUBB|AlkAg FDA approved FDA approved
706363 Arsenic trioxide Apo FDA approved FDA approved
707389 Eribulin mesilate TUBB FDA approved FDA approved
712807 Capecitabine Ds|TYMS FDA approved FDA approved
713563 Exemestane Ho|CYP19A1 FDA approved FDA approved
715055 Gefitinib PK:YK,EGFR FDA approved FDA approved
718781 Erlotinib PK:YK,EGFR FDA approved FDA approved
719276 Fulvestrant AM|Ho|ESR|SERM FDA approved FDA approved
719344 Anastrozole Ho|CYP19A1 FDA approved FDA approved
719345 Letrozole Ho|CYP19A1 FDA approved FDA approved
719627 Celecoxib AM|PTGS2|COX2|NonCan:NSAID FDA approved FDA approved
721517 Zoledronate AM|NonCan:Anti-bone resorp FDA approved FDA approved
722664 Nelfinavir PSM FDA approved FDA approved
724772 Sorafenib PK:YK,PDGFR,BRAF,KIT,VEGFR,Multikinase FDA approved FDA approved
726630 Belinostat HDAC FDA approved FDA approved
727989 Lapatinib PK:STK,YK,MET,EGFR,ERBB2,KIT,RAF,VEGFR FDA approved FDA approved
728073 Irinotecan TOP1 FDA approved FDA approved
732517 Dasatinib BCR-ABL|PK:YK,PDGFR,KIT FDA approved FDA approved
733504 Everolimus PK:STK,MTOR FDA approved FDA approved
737754 Pazopanib PK:YK,PDGFR,FGFR,KIT,VEGFR FDA approved FDA approved
741078 Selumetinib PK:STK,YK,MAP2K,MAP2K1,MAP2K2 FDA approved FDA approved
741485 Finasteride FDA approved FDA approved
743414 Imatinib BCR-ABL|PK:YK FDA approved FDA approved
744009 Sildenafil FDA approved FDA approved
745750 Lapatinib PK:STK,YK,MET,EGFR,ERBB2,KIT,RAF,VEGFR FDA approved FDA approved
746847 Leuprolide Ho FDA approved FDA approved
747167 Nelfinavir PSM FDA approved FDA approved
747599 Nilotinib BCR-ABL|PK:YK FDA approved FDA approved
747856 Olaparib PARP|PARP1 FDA approved FDA approved
747971 Sorafenib PK:YK,PDGFR,BRAF,KIT,VEGFR,Multikinase FDA approved FDA approved
747972 Lenalidomide FT|Immunomodulatory FDA approved FDA approved
747973 Ixabepilone TUBB|Tu-stab FDA approved FDA approved
747974 Raloxifene Ho|SERM FDA approved FDA approved
749226 Abiraterone Ho|CYP17A1 FDA approved FDA approved
749227 Abiraterone Ho|CYP17A1 FDA approved FDA approved
750690 Sunitinib PK:YK,PDGFR,KIT,VEGFR,Multikinase FDA approved FDA approved
750691 Afatinib PK:YK,EGFR FDA approved FDA approved
752782 Pazopanib PK:YK,PDGFR,FGFR,KIT,VEGFR FDA approved FDA approved
753686 Olaparib PARP|PARP1 FDA approved FDA approved
754143 Depsipeptide HDAC FDA approved FDA approved
754230 pralatrexate Df|CTNNB1|DHFR FDA approved FDA approved
754355 Niraparib PARP|PARP1 FDA approved FDA approved
754363 Plerixafor CXCR4 FDA approved FDA approved
755384 Pemetrexed Df|AM|GARTF|DHFR FDA approved FDA approved
755389 Bosutinib STAT|BCR-ABL|STAT5A/B|PK:YK,LYN,SRC,HCK FDA approved FDA approved
755401 Golotimod STAT|STAT3 FDA approved FDA approved
755404 Flurbiprofen FDA approved FDA approved
755605 Enzalutamide Ho|AR FDA approved FDA approved
755764 Fluphenazine NonCan:Psy FDA approved FDA approved
755767 Tacrolimus FDA approved FDA approved
755768 Fluphenazine NonCan:Psy FDA approved FDA approved
755809 Vismodegib SMO|PK:YK FDA approved FDA approved
755841 Actinomycin D Db FDA approved FDA approved
755880 Mitomycin A2 FDA approved FDA approved
755980 Lenvatinib PK:YK,PDGFR,FGFR,VEGFR,RET FDA approved FDA approved
755984 Pralatrexate Df|CTNNB1|DHFR FDA approved FDA approved
755985 Nelarabine Ds FDA approved FDA approved
755986 Vismodegib SMO|PK:YK FDA approved FDA approved
756644 Rucaparib PARP|PARP1 FDA approved FDA approved
756645 Crizotinib PK:YK,MET,ALK FDA approved FDA approved
756655 Bortezomib PSM FDA approved FDA approved
756661 Chlorpromazine NonCan:Psy FDA approved FDA approved
756689 Chlorpromazine NonCan:Psy FDA approved FDA approved
756714 Cytarabine Ds FDA approved FDA approved
756717 DAUNORUBICIN TOP2 FDA approved FDA approved
756738 DIGOXIN NonCan:CardG FDA approved FDA approved
757027 ETHINYL ESTRADIOL Ho FDA approved FDA approved
757036 Fluorouracil Ds|Rs|TYMS FDA approved FDA approved
757087 Nitrogen mustard A7|AlkAg FDA approved FDA approved
757098 Melphalan A7|AlkAg FDA approved FDA approved
757307 Acrichine Db|AP FDA approved FDA approved
757345 Tamoxifen Ho|SERM FDA approved FDA approved
757348 6-Thioguanine Ds|IMPDH2|IMPDH FDA approved FDA approved
757363 TYROTHRICIN NonCan:Ant FDA approved FDA approved
757384 Vinblastine TUBB|Tu-frag FDA approved FDA approved
757436 Cabozantinib PK:YK,MET,AXL,KIT,VEGFR,FLT3,RET FDA approved FDA approved
757439 Neratinib PK:YK,EGFR,ERBB2 FDA approved FDA approved
757441 Axitinib PK:YK,PDGFR,VEGFR FDA approved FDA approved
757443 Finasteride FDA approved FDA approved
757804 Etoposide TOP2 FDA approved FDA approved
757816 Fluphenazine NonCan:Psy FDA approved FDA approved
758186 Azacitidine DNMT FDA approved FDA approved
758230 Floxuridine Ds|TYMS FDA approved FDA approved
758244 tepotinib PK:YK,MET FDA approved FDA approved
758246 Trametinib PK:STK,MAP2K,MAP2K1,MAP2K2 FDA approved FDA approved
758247 Palbociclib PK:STK,CDK,CDK4,CDK6 FDA approved FDA approved
758252 Carfilzomib PSM FDA approved FDA approved
758253 Homoharringtonine Apo|Ang|Pi FDA approved FDA approved
758254 Ixazomib citrate PSM FDA approved FDA approved
758255 Teniposide TOP2 FDA approved FDA approved
758487 Ponatinib BCR-ABL|PK:YK FDA approved FDA approved
758612 Bleomycin Db FDA approved FDA approved
758645 Paclitaxel TUBB|Tu-stab FDA approved FDA approved
758664 Rapamycin PK:STK,MTOR FDA approved FDA approved
758667 Teniposide TOP2 FDA approved FDA approved
758706 Simvastatin AM|NonCan:Chol FDA approved FDA approved
758774 Belinostat HDAC FDA approved FDA approved
759155 Doxorubicin TOP2 FDA approved FDA approved
759174 Vincristine TUBB|Tu-frag FDA approved FDA approved
759178 Pipamperone NonCan:Psy FDA approved FDA approved
759195 Epirubicin TOP2 FDA approved FDA approved
759224 Idelalisib PK:PIK3 FDA approved FDA approved
759263 Topotecan TOP1 FDA approved FDA approved
759274 ARSENIC TRIOXIDE Apo FDA approved FDA approved
759614 6-Mercaptopurine Ds|PPAT FDA approved FDA approved
759850 Docetaxel TUBB|Tu-stab FDA approved FDA approved
759852 Vorinostat HDAC FDA approved FDA approved
759856 Gefitinib PK:YK,EGFR FDA approved FDA approved
759857 Clofarabine Ds FDA approved FDA approved
759877 Dasatinib BCR-ABL|PK:YK,PDGFR,KIT FDA approved FDA approved
759878 Irinotecan TOP1 FDA approved FDA approved
760087 VINORELBINE TUBB|Tu-frag FDA approved FDA approved
760443 Copanlisib PK:PIK3 FDA approved FDA approved
760766 Vandetanib PK:STK,YK,PDGFR,EGFR,VEGFR,RET FDA approved FDA approved
761068 Cabozantinib PK:YK,MET,AXL,KIT,VEGFR,FLT3,RET FDA approved FDA approved
761190 Panobinostat HDAC FDA approved FDA approved
761191 brigatinib PK:YK,ALK,EGFR FDA approved FDA approved
761385 Sonidegib SMO|Hg-Smo FDA approved FDA approved
761386 Sonidegib SMO|Hg-Smo FDA approved FDA approved
761388 Plerixafor CXCR4 FDA approved FDA approved
761389 Raloxifene Ho|SERM FDA approved FDA approved
761431 Vemurafenib PK:YK,BRAF FDA approved FDA approved
761432 Cabazitaxel TUBB|Tu-stab FDA approved FDA approved
761910 Ibrutinib PK:YK,BTK FDA approved FDA approved
763371 Ruxolitinib PK:YK,JAK,JAK1,JAK2 FDA approved FDA approved
763932 Regorafenib GTPase|PK:STK,YK,PDGFR,FGFR,KIT,MAP2K,RAF,VEGFR,RET,Multikinase FDA approved FDA approved
764040 Alectinib PK:YK,ALK FDA approved FDA approved
764042 ARRY-162 PK:STK,MAP2K,MAP2K1,MAP2K2 FDA approved FDA approved
764134 Dabrafenib PK:BRAF FDA approved FDA approved
764778 Ivacaftor FDA approved FDA approved
764821 Alectinib PK:YK,ALK FDA approved FDA approved
765396 BMN-673 PARP1 FDA approved FDA approved
765694 Bosutinib STAT|BCR-ABL|STAT5A/B|PK:YK,LYN,SRC,HCK FDA approved FDA approved
765888 Dacomitinib PK:EGFR,ERBB2 FDA approved FDA approved
766270 ABT-199 BCL2 FDA approved FDA approved
767125 BMN-673 PARP1 FDA approved FDA approved
768068 Cobimetinib (isomer 1) PK:MAP2K,MAP2K1 FDA approved FDA approved
768069 Cobimetinib (isomer 1) PK:MAP2K,MAP2K1 FDA approved FDA approved
768073 LY-2835219 PK:CDK,CDK4,CDK6 FDA approved FDA approved
771649 ARN-509 AR FDA approved FDA approved
772469 IPI-145 PK:PIK3 FDA approved FDA approved
774769 NMS-E628 PK:ALK FDA approved FDA approved
775351 Pomalidomide Immunomodulatory FDA approved FDA approved
775772 PF-04449913 SMO FDA approved FDA approved
776422 LDK-378 PK:ALK FDA approved FDA approved
777193 LDK-378 PK:ALK FDA approved FDA approved
777878 TABRECTA PK:MET FDA approved FDA approved
778304 Encorafenib PK:BRAF FDA approved FDA approved
778590 Cobimetinib (isomer 1) PK:MAP2K,MAP2K1 FDA approved FDA approved
778909 LEE-011 PK:CDK,CDK4,CDK6 FDA approved FDA approved
779217 Osimertinib PK:EGFR FDA approved FDA approved
780108 PF-06463922 PK:ROS1,ALK FDA approved FDA approved
781556 JNJ-42756493 PK:FGFR,FGFR1,FGFR2,FGFR3,FGFR4 FDA approved FDA approved
785497 INCB-024360 IDO1 FDA approved FDA approved
785570 LOXO-101 PK:NTRK FDA approved FDA approved
787457 brigatinib PK:YK,ALK,EGFR FDA approved FDA approved
787846 gilteritinib PK:AXL,FLT3 FDA approved FDA approved
788120 Enasidenib IDH2 FDA approved FDA approved
788948 Vistonuridine TUBB|FU-Antidote FDA approved FDA approved
789102 ivosidenib IDH1 FDA approved FDA approved
791164 Acalabrutinib PK:BTK FDA approved FDA approved
797937 Sulfatinib PK:YK,FGFR FDA approved FDA approved
800405 umbralisib FDA approved FDA approved
809693 Copanlisib PK:PIK3 FDA approved FDA approved
813783 Trabectedin A2 FDA approved FDA approved