CellMiner™ is a web application generated by the Genomics & Bioinformatics Group, LMP, CCR, NCI that facilitates systems biology through the retrieval and integration of the molecular and pharmacological data sets for the NCI-60 cell lines. The NCI-60, a panel of 60 diverse human cancer cell lines used by the Developmental Therapeutics Program of the U.S. National Cancer Institute to screen over 100,000 chemical compounds and natural products (since 1990).

To cite the tool, the primary literature references are (Shankavaram, BMC Genomic, 2009 and Reinhold, Cancer Res, 2012).

Press articles reviewing CellMiner may be accessed here (NCI featured newsCancer Discovery) (CCR Connections) (Slashdot) (NCI press release) (FierceBiotechIT).

Press articles reviewing the Exome data set may be accessed here (Time Magazine) (NPR) (Forbes) (Los Angeles Times) (U.S. News Health).

Subsequent builds will include additional molecular data sets and integrative capabilities.

How to find the information you need in CellMiner using the above tabs

Resources
For other bioinformatic tools and database resources from GBG go to the Discover website home page.
For additional drug, dataset and molecular target data see the NCI Developmental Therapeutics Program site.
For access to our Cytogenetics (spectral karyotyping) of the NCI-60, type 'NCI-60' in the NCBI's sky database search page.

CellMiner Development Team

Margot Sunshine, Sudhir Varma, William Reinhold and Yves Pommier prior contributors